| Type of ceramics | Advantages | Disadvantages | References |
| HAP | Resembles mineral phase of bone | Poor mechanical properties | [27,29] |
| Can be doped with multiple ions to closely mimic bone mineral | Slow degradation rates in vivo |
| High biocompatibility can be used in a plethora of formulations |
| Osteoconductivity and osteoinductivity |
| TCP | Faster in vivo degradation | Poor mechanical properties | [33,34] |
| Osteoconductivity | Higher biodegradability |
| Can be doped with multiple ions to tune bioactivity and degradation |
| High biocompatibility |
| BCP | Bioresorbability | Low mechanical property | [36-38] |
| Osteoconductivity and osteoinductivity | Rapid degradability |
| High biocompatibility |
| BGs | Biocompatible | Suboptimal biodegradation | [40,41] |
| Enhanced bone integration | Poor mechanical properties |
| Improved biodegradation | Lower biodegradability |
", "page_width": 1191, "page_height": 1565, "role": "table_html", "role_confidence": 0.85, "evidence": ["media label: table"], "seed_role": "media_asset", "seed_confidence": 0.85, "seed_evidence": ["media label: table"], "span_metadata": [{"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 4, "page": 6, "raw_label": "table", "text": "| Type of ceramics | Advantages | Disadvantages | References |
| HAP | Resembles mineral phase of bone | Poor mechanical properties | [27,29] |
| Can be doped with multiple ions to closely mimic bone mineral | Slow degradation rates in vivo |
| High biocompatibility can be used in a plethora of formulations |
| Osteoconductivity and osteoinductivity |
| TCP | Faster in vivo degradation | Poor mechanical properties | [33,34] |
| Osteoconductivity | Higher biodegradability |
| Can be doped with multiple ions to tune bioactivity and degradation |
| High biocompatibility |
| BCP | Bioresorbability | Low mechanical property | [36-38] |
| Osteoconductivity and osteoinductivity | Rapid degradability |
| High biocompatibility |
| BGs | Biocompatible | Suboptimal biodegradation | [40,41] |
| Enhanced bone integration | Poor mechanical properties |
| Improved biodegradation | Lower biodegradability |
", "bbox": [90, 184, 1086, 558], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "| Type of ceramics | Advantages | Disadvantages | References |
| HAP | Resembles mineral phase of bone | Poor mechanical properties | [27,29] |
| Can be doped with multiple ions to closely mimic bone mineral | Slow degradation rates in vivo |
| High biocompatibility can be used in a plethora of formulations |
| Osteoconductivity and osteoinductivity |
| TCP | Faster in vivo degradation | Poor mechanical properties | [33,34] |
| Osteoconductivity | Higher biodegradability |
| Can be doped with multiple ions to tune bioactivity and degradation |
| High biocompatibility |
| BCP | Bioresorbability | Low mechanical property | [36-38] |
| Osteoconductivity and osteoinductivity | Rapid degradability |
| High biocompatibility |
| BGs | Biocompatible | Suboptimal biodegradation | [40,41] |
| Enhanced bone integration | Poor mechanical properties |
| Improved biodegradation | Lower biodegradability |
"}, "layout_signature": {"width": 996, "width_bucket": 1000, "height": 374, "left": 90, "top": 184, "right": 1086, "bottom": 558, "x_center": 588.0, "x_center_bucket": 600, "y_center": 371.0, "x_ratio": 0.4937, "y_ratio": 0.2371, "width_ratio": 0.8363, "height_ratio": 0.239, "line_count": 1}, "span_signature": {"font_size": 6.97, "font_size_median": 6.97, "font_size_bucket": 7.0, "font_family_norm": "ScalaSansPro-Regular", "bold": false, "italic": true, "span_count": 43}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_140", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.0, "decision": "body", "evidence": []}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"], "asset_family_hint": "table_like", "asset_family_confidence": 0.7, "asset_family_evidence": ["raw_label:table"]}
+{"paper_id": "2HEUD5P9", "page": 6, "block_id": 5, "raw_label": "text", "raw_order": 1, "bbox": [89, 609, 582, 1073], "text": "classified as natural or synthetic polymers. Natural polymers such as polysaccharides (chitosan, hyaluronic acid, cellulose, alginate, starch, carrageenan, and gellan gum) and proteins (collagen, gelatin, fibrin, and silk fibroin) are suitable for bone tissue regeneration because of their natural origin, good biocompatibility and biodegradability, and similarity to the structural native ECM of tissues. $ ^{[51,52]} $ Chitosan, alginate, hyaluronic acid, collagen, gelatin, and silk fibroin are commonly used in bone tissue engineering. Although bioactive natural polymers can interact with host tissues, they have drawbacks such as insufficient mechanical properties, batch variation, high degradation rates, and immunogenicity. $ ^{[53]} $ Synthetic polymers exhibit tailored structures and characteristics owing to the appropriate design of their functional groups. Polylactic acid (PLA), polyglycolic acid (PGA), polycaprolactone (PCL), polylactic-coglycolic acid (PLGA), and other synthetic polymers can be fabricated with different pore sizes, porosities, degradation rates, morphologies, and mechanical properties. However, synthetic polymers lack bioactivity and cell interactions and exhibit reduced osteoconductivity. Hence, synthetic polymers are often mixed with biomaterials for bone repair and regeneration.", "page_width": 1191, "page_height": 1565, "role": "body_paragraph", "role_confidence": 0.6, "evidence": ["default body_paragraph for text label"], "seed_role": "body_paragraph", "seed_confidence": 0.6, "seed_evidence": ["default body_paragraph for text label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 5, "page": 6, "raw_label": "text", "text": "classified as natural or synthetic polymers. Natural polymers such as polysaccharides (chitosan, hyaluronic acid, cellulose, alginate, starch, carrageenan, and gellan gum) and proteins (collagen, gelatin, fibrin, and silk fibroin) are suitable for bone tissue regeneration because of their natural origin, good biocompatibility and biodegradability, and similarity to the structural native ECM of tissues. $ ^{[51,52]} $ Chitosan, alginate, hyaluronic acid, collagen, gelatin, and silk fibroin are commonly used in bone tissue engineering. Although bioactive natural polymers can interact with host tissues, they have drawbacks such as insufficient mechanical properties, batch variation, high degradation rates, and immunogenicity. $ ^{[53]} $ Synthetic polymers exhibit tailored structures and characteristics owing to the appropriate design of their functional groups. Polylactic acid (PLA), polyglycolic acid (PGA), polycaprolactone (PCL), polylactic-coglycolic acid (PLGA), and other synthetic polymers can be fabricated with different pore sizes, porosities, degradation rates, morphologies, and mechanical properties. However, synthetic polymers lack bioactivity and cell interactions and exhibit reduced osteoconductivity. Hence, synthetic polymers are often mixed with biomaterials for bone repair and regeneration.", "bbox": [89, 609, 582, 1073], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "classified as natural or synthetic polymers. Natural polymers such as polysaccharides (chitosan, hyaluronic acid, cellulose, alginate, starch, carrageenan, and gellan gum) and proteins (collagen, gelatin, fibrin, and silk fibroin) are suitable for bone tissue regeneration because of their natural origin, good biocompatibility and biodegradability, and similarity to the structural native ECM of tissues. $ ^{[51,52]} $ Chitosan, alginate, hyaluronic acid, collagen, gelatin, and silk fibroin are commonly used in bone tissue engineering. Although bioactive natural polymers can interact with host tissues, they have drawbacks such as insufficient mechanical properties, batch variation, high degradation rates, and immunogenicity. $ ^{[53]} $ Synthetic polymers exhibit tailored structures and characteristics owing to the appropriate design of their functional groups. Polylactic acid (PLA), polyglycolic acid (PGA), polycaprolactone (PCL), polylactic-coglycolic acid (PLGA), and other synthetic polymers can be fabricated with different pore sizes, porosities, degradation rates, morphologies, and mechanical properties. However, synthetic polymers lack bioactivity and cell interactions and exhibit reduced osteoconductivity. Hence, synthetic polymers are often mixed with biomaterials for bone repair and regeneration."}, "layout_signature": {"width": 493, "width_bucket": 500, "height": 464, "left": 89, "top": 609, "right": 582, "bottom": 1073, "x_center": 335.5, "x_center_bucket": 325, "y_center": 841.0, "x_ratio": 0.2817, "y_ratio": 0.5374, "width_ratio": 0.4139, "height_ratio": 0.2965, "line_count": 1}, "span_signature": {"font_size": 8.86, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaPro-Regular", "bold": false, "italic": true, "span_count": 161}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_139", "display_cluster_candidate_id": "disp_27_0", "layout_region": "display_zone", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 6, "block_id": 6, "raw_label": "paragraph_title", "raw_order": 2, "bbox": [92, 1114, 269, 1136], "text": "2.2.1. Natural Polymers", "page_width": 1191, "page_height": 1565, "role": "sub_subsection_heading", "role_confidence": 0.85, "evidence": ["paragraph_title label with numbering: 2.2.1. Natural Polymers"], "seed_role": "sub_subsection_heading", "seed_confidence": 0.85, "seed_evidence": ["paragraph_title label with numbering: 2.2.1. Natural Polymers"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaSansPro-Italic", "flags": 6, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 6, "page": 6, "raw_label": "paragraph_title", "text": "2.2.1. Natural Polymers", "bbox": [92, 1114, 269, 1136], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "heading_numbered", "raw_marker": "2.2.1", "number": "2.2.1", "kind": "heading", "normalized_text": "2.2.1. Natural Polymers"}, "layout_signature": {"width": 177, "width_bucket": 175, "height": 22, "left": 92, "top": 1114, "right": 269, "bottom": 1136, "x_center": 180.5, "x_center_bucket": 175, "y_center": 1125.0, "x_ratio": 0.1516, "y_ratio": 0.7188, "width_ratio": 0.1486, "height_ratio": 0.0141, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaSansPro-Italic", "bold": false, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_140", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 6, "block_id": 7, "raw_label": "text", "raw_order": 3, "bbox": [89, 1157, 583, 1445], "text": "Chitosan is made up of glucosamine and N-acetyl glucosamine units that are linked together by $ \\beta(1-4) $ glycosidic bonds. Chitosan is a versatile natural polymer derived from the partial deacetylation of chitin. It has good biocompatibility and biodegradability, low toxicity, and antibacterial properties, and is extensively used in bone scaffolds. Chitosan can be degraded into absorbable, nontoxic, small-molecule polysaccharides and amino acids by chitosanolytic enzymes. $ ^{[54]} $ Considering its formulation and structure, chitosan can promote cell adhesion and proliferation of osteoblasts and MSCs, and enhance the formation of mineralized bone matrix. $ ^{[55,56]} $ Lei et al. fabricated strontium hydroxypatite (SrHAP)/chitosan nanohybrid scaffolds with interconnected macropores by a freeze-drying protocol. This composite with high stem cell affinity could promote cell proliferation, adhesion, and osteogenesis in vitro and upregulate the expression of osteogenic markers and alkaline phosphatase (ALP) activity. $ ^{[57]} $ Polycaprolactone/chitosan nanofibrous membrane by electrospinning could promote cell proliferation and adhesion, upregulate the expression of osteogenic genes, and induce ALP activity and calcium deposition in stem cells. $ ^{[58]} $ Jahan et al. developed chitosan-apatite hydrogels with an interconnected porous structure, and this scaffold could improve cell behavior and showed potential application for bone repair. $ ^{[59]} $ However, low mechanical strength and solubility, and allergic reactions are the main drawbacks of chitosan. Therefore, biopolymers, ceramics, and metals are often combined with chitosan for bone repair and regeneration. Furthermore, research on how to improve the bioactivity and biodegradability of chitosan by changing its physicochemical properties and constructing scaffold materials that deliver different bioactive substances is needed to be investigated.", "page_width": 1191, "page_height": 1565, "role": "body_paragraph", "role_confidence": 0.6, "evidence": ["default body_paragraph for text label"], "seed_role": "body_paragraph", "seed_confidence": 0.6, "seed_evidence": ["default body_paragraph for text label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "STIXMath-Italic", "flags": 6, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 7, "page": 6, "raw_label": "text", "text": "Chitosan is made up of glucosamine and N-acetyl glucosamine units that are linked together by $ \\beta(1-4) $ glycosidic bonds. Chitosan is a versatile natural polymer derived from the partial deacetylation of chitin. It has good biocompatibility and biodegradability, low toxicity, and antibacterial properties, and is extensively used in bone scaffolds. Chitosan can be degraded into absorbable, nontoxic, small-molecule polysaccharides and amino acids by chitosanolytic enzymes. $ ^{[54]} $ Considering its formulation and structure, chitosan can promote cell adhesion and proliferation of osteoblasts and MSCs, and enhance the formation of mineralized bone matrix. $ ^{[55,56]} $ Lei et al. fabricated strontium hydroxypatite (SrHAP)/chitosan nanohybrid scaffolds with interconnected macropores by a freeze-drying protocol. This composite with high stem cell affinity could promote cell proliferation, adhesion, and osteogenesis in vitro and upregulate the expression of osteogenic markers and alkaline phosphatase (ALP) activity. $ ^{[57]} $ Polycaprolactone/chitosan nanofibrous membrane by electrospinning could promote cell proliferation and adhesion, upregulate the expression of osteogenic genes, and induce ALP activity and calcium deposition in stem cells. $ ^{[58]} $ Jahan et al. developed chitosan-apatite hydrogels with an interconnected porous structure, and this scaffold could improve cell behavior and showed potential application for bone repair. $ ^{[59]} $ However, low mechanical strength and solubility, and allergic reactions are the main drawbacks of chitosan. Therefore, biopolymers, ceramics, and metals are often combined with chitosan for bone repair and regeneration. Furthermore, research on how to improve the bioactivity and biodegradability of chitosan by changing its physicochemical properties and constructing scaffold materials that deliver different bioactive substances is needed to be investigated.", "bbox": [89, 1157, 583, 1445], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "Chitosan is made up of glucosamine and N-acetyl glucosamine units that are linked together by $ \\beta(1-4) $ glycosidic bonds. Chitosan is a versatile natural polymer derived from the partial deacetylation of chitin. It has good biocompatibility and biodegradability, low toxicity, and antibacterial properties, and is extensively used in bone scaffolds. Chitosan can be degraded into absorbable, nontoxic, small-molecule polysaccharides and amino acids by chitosanolytic enzymes. $ ^{[54]} $ Considering its formulation and structure, chitosan can promote cell adhesion and proliferation of osteoblasts and MSCs, and enhance the formation of mineralized bone matrix. $ ^{[55,56]} $ Lei et al. fabricated strontium hydroxypatite (SrHAP)/chitosan nanohybrid scaffolds with interconnected macropores by a freeze-drying protocol. This composite with high stem cell affinity could promote cell proliferation, adhesion, and osteogenesis in vitro and upregulate the expression of osteogenic markers and alkaline phosphatase (ALP) activity. $ ^{[57]} $ Polycaprolactone/chitosan nanofibrous membrane by electrospinning could promote cell proliferation and adhesion, upregulate the expression of osteogenic genes, and induce ALP activity and calcium deposition in stem cells. $ ^{[58]} $ Jahan et al. developed chitosan-apatite hydrogels with an interconnected porous structure, and this scaffold could improve cell behavior and showed potential application for bone repair. $ ^{[59]} $ However, low mechanical strength and solubility, and allergic reactions are the main drawbacks of chitosan. Therefore, biopolymers, ceramics, and metals are often combined with chitosan for bone repair and regeneration. Furthermore, research on how to improve the bioactivity and biodegradability of chitosan by changing its physicochemical properties and constructing scaffold materials that deliver different bioactive substances is needed to be investigated."}, "layout_signature": {"width": 494, "width_bucket": 500, "height": 288, "left": 89, "top": 1157, "right": 583, "bottom": 1445, "x_center": 336.0, "x_center_bucket": 325, "y_center": 1301.0, "x_ratio": 0.2821, "y_ratio": 0.8313, "width_ratio": 0.4148, "height_ratio": 0.184, "line_count": 1}, "span_signature": {"font_size": 8.83, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaPro-Regular", "bold": false, "italic": true, "span_count": 135}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_139", "display_cluster_candidate_id": "disp_27_0", "layout_region": "display_zone", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 6, "block_id": 8, "raw_label": "text", "raw_order": 4, "bbox": [598, 609, 1093, 982], "text": "", "page_width": 1191, "page_height": 1565, "role": "ocr_text_missing", "role_confidence": 0.8, "evidence": ["ocr detected text region (raw_label=text) but no text extracted; no pdf backfill available"], "seed_role": "ocr_text_missing", "seed_confidence": 0.8, "seed_evidence": ["ocr detected text region (raw_label=text) but no text extracted; no pdf backfill available"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 8, "page": 6, "raw_label": "text", "text": "", "bbox": [598, 609, 1093, 982], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "empty", "raw_marker": null, "number": null, "kind": null, "normalized_text": ""}, "layout_signature": {"width": 495, "width_bucket": 500, "height": 373, "left": 598, "top": 609, "right": 1093, "bottom": 982, "x_center": 845.5, "x_center_bucket": 850, "y_center": 795.5, "x_ratio": 0.7099, "y_ratio": 0.5083, "width_ratio": 0.4156, "height_ratio": 0.2383, "line_count": 1}, "span_signature": {"font_size": 8.74, "font_size_median": 8.97, "font_size_bucket": 8.5, "font_family_norm": "ScalaPro-Regular", "bold": false, "italic": true, "span_count": 120}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": "pdf_text_layer_fallback_rejected", "_ocr_raw_status": "missing_text_rejected", "_ocr_raw_error_type": "backfill_overlaps_existing_text_block", "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "_needs_pdf_fallback": true, "reading_band_id": "band_140", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 6, "block_id": 9, "raw_label": "text", "raw_order": 5, "bbox": [598, 982, 1093, 1445], "text": "Alginate is a linear polysaccharide that contains β-D-mannuronate (M) and α-L-guluronate (G) residues, which are linked together in a (1, 4) configuration. Alginate extracted from brown seaweed possesses attractive properties, including high abundance, low cost, biocompatibility, biodegradability, non-toxicity, and non-immunity.[60] The mechanical strength, cell affinity, biodegradability, and gel-forming properties of alginate can be finely tuned through various physicochemical modifications. Moreover, various hydrogels, microcapsules, microspheres, fibers, foams, and sponges can be fabricated using alginate.[61] A variety of crosslinking protocols have been applied to obtain alginate and its composites for bone repair and regeneration.[61] It has been reported that alginate-based scaffolds with bone regeneration properties have the potential for use in bone tissue engineering applications. HAP combined with alginate enhanced the mechanical strength of the scaffold, and the composite significantly promoted osteogenic differentiation.[62] Luo et al. developed 3D porous alginate scaffolds composited with bone-forming peptide-1, and the data revealed that the scaffold promoted bioactivity and osteogenic differentiation in vitro and bone regenerative capability in vivo, and could sustainably", "page_width": 1191, "page_height": 1565, "role": "body_paragraph", "role_confidence": 0.6, "evidence": ["default body_paragraph for text label"], "seed_role": "body_paragraph", "seed_confidence": 0.6, "seed_evidence": ["default body_paragraph for text label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "STIXMath-Italic", "flags": 6, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "STIXMath-Italic", "flags": 6, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "STIXMath-Italic", "flags": 6, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "STIXMath-Italic", "flags": 6, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 9, "page": 6, "raw_label": "text", "text": "Alginate is a linear polysaccharide that contains β-D-mannuronate (M) and α-L-guluronate (G) residues, which are linked together in a (1, 4) configuration. Alginate extracted from brown seaweed possesses attractive properties, including high abundance, low cost, biocompatibility, biodegradability, non-toxicity, and non-immunity.[60] The mechanical strength, cell affinity, biodegradability, and gel-forming properties of alginate can be finely tuned through various physicochemical modifications. Moreover, various hydrogels, microcapsules, microspheres, fibers, foams, and sponges can be fabricated using alginate.[61] A variety of crosslinking protocols have been applied to obtain alginate and its composites for bone repair and regeneration.[61] It has been reported that alginate-based scaffolds with bone regeneration properties have the potential for use in bone tissue engineering applications. HAP combined with alginate enhanced the mechanical strength of the scaffold, and the composite significantly promoted osteogenic differentiation.[62] Luo et al. developed 3D porous alginate scaffolds composited with bone-forming peptide-1, and the data revealed that the scaffold promoted bioactivity and osteogenic differentiation in vitro and bone regenerative capability in vivo, and could sustainably", "bbox": [598, 982, 1093, 1445], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "Alginate is a linear polysaccharide that contains β-D-mannuronate (M) and α-L-guluronate (G) residues, which are linked together in a (1, 4) configuration. Alginate extracted from brown seaweed possesses attractive properties, including high abundance, low cost, biocompatibility, biodegradability, non-toxicity, and non-immunity.[60] The mechanical strength, cell affinity, biodegradability, and gel-forming properties of alginate can be finely tuned through various physicochemical modifications. Moreover, various hydrogels, microcapsules, microspheres, fibers, foams, and sponges can be fabricated using alginate.[61] A variety of crosslinking protocols have been applied to obtain alginate and its composites for bone repair and regeneration.[61] It has been reported that alginate-based scaffolds with bone regeneration properties have the potential for use in bone tissue engineering applications. HAP combined with alginate enhanced the mechanical strength of the scaffold, and the composite significantly promoted osteogenic differentiation.[62] Luo et al. developed 3D porous alginate scaffolds composited with bone-forming peptide-1, and the data revealed that the scaffold promoted bioactivity and osteogenic differentiation in vitro and bone regenerative capability in vivo, and could sustainably"}, "layout_signature": {"width": 495, "width_bucket": 500, "height": 463, "left": 598, "top": 982, "right": 1093, "bottom": 1445, "x_center": 845.5, "x_center_bucket": 850, "y_center": 1213.5, "x_ratio": 0.7099, "y_ratio": 0.7754, "width_ratio": 0.4156, "height_ratio": 0.2958, "line_count": 1}, "span_signature": {"font_size": 8.81, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaPro-Regular", "bold": false, "italic": true, "span_count": 229}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_138", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 6, "block_id": 10, "raw_label": "footer", "raw_order": null, "bbox": [94, 1487, 283, 1505], "text": "Small Methods 2024, 8, 2301283", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["footer label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["footer label"], "span_metadata": [{"size": 6.973800182342529, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 10, "page": 6, "raw_label": "footer", "text": "Small Methods 2024, 8, 2301283", "bbox": [94, 1487, 283, 1505], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "Small Methods 2024, 8, 2301283"}, "layout_signature": {"width": 189, "width_bucket": 200, "height": 18, "left": 94, "top": 1487, "right": 283, "bottom": 1505, "x_center": 188.5, "x_center_bucket": 200, "y_center": 1496.0, "x_ratio": 0.1583, "y_ratio": 0.9559, "width_ratio": 0.1587, "height_ratio": 0.0115, "line_count": 1}, "span_signature": {"font_size": 6.97, "font_size_median": 6.97, "font_size_bucket": 7.0, "font_family_norm": "ScalaSansPro-Italic", "bold": true, "italic": true, "span_count": 5}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_141", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "hard", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 6, "block_id": 11, "raw_label": "number", "raw_order": null, "bbox": [525, 1484, 658, 1507], "text": "2301283 (6 of 27)", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["page number label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["page number label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaSansPro-Bold", "flags": 20, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 11, "page": 6, "raw_label": "number", "text": "2301283 (6 of 27)", "bbox": [525, 1484, 658, 1507], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_dot", "raw_marker": "2301283", "number": 2301283, "kind": "reference", "normalized_text": "2301283 (6 of 27)"}, "layout_signature": {"width": 133, "width_bucket": 125, "height": 23, "left": 525, "top": 1484, "right": 658, "bottom": 1507, "x_center": 591.5, "x_center_bucket": 600, "y_center": 1495.5, "x_ratio": 0.4966, "y_ratio": 0.9556, "width_ratio": 0.1117, "height_ratio": 0.0147, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaSansPro-Bold", "bold": true, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_142", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 6, "block_id": 12, "raw_label": "footer", "raw_order": null, "bbox": [931, 1487, 1090, 1506], "text": "© 2024 Wiley-VCH GmbH", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["footer label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["footer label"], "span_metadata": [{"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 12, "page": 6, "raw_label": "footer", "text": "© 2024 Wiley-VCH GmbH", "bbox": [931, 1487, 1090, 1506], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "© 2024 Wiley-VCH GmbH"}, "layout_signature": {"width": 159, "width_bucket": 150, "height": 19, "left": 931, "top": 1487, "right": 1090, "bottom": 1506, "x_center": 1010.5, "x_center_bucket": 1000, "y_center": 1496.5, "x_ratio": 0.8484, "y_ratio": 0.9562, "width_ratio": 0.1335, "height_ratio": 0.0121, "line_count": 1}, "span_signature": {"font_size": 6.97, "font_size_median": 6.97, "font_size_bucket": 7.0, "font_family_norm": "ScalaSansPro-Regular", "bold": false, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_142", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 6, "block_id": 13, "raw_label": "aside_text", "raw_order": null, "bbox": [1154, 30, 1171, 1534], "text": "23699608, 2024, 8, Downloaded from https://onlinelibrary.wiley.com/doi/10.1002/smkt.202301283 by Shandong University Library, Wiley Online Library on [18/02/2026]. See the Terms and Conditions (https://onlinelibrary.wiley.com/terms-and-conditions) on Wiley Online Library for rules of use; OA articles are governed by the applicable Creative Commons License.", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.95, "evidence": ["margin-band narrow/tall geometry; treated as noise"], "seed_role": "noise", "seed_confidence": 0.95, "seed_evidence": ["margin-band narrow/tall geometry; treated as noise"], "span_metadata": [{"size": 5.03000020980835, "font": "Times-Roman", "flags": 4, "color": 0, "dir": [0.0, 1.0], "wmode": 0}], "raw_observation": {"block_id": 13, "page": 6, "raw_label": "aside_text", "text": "23699608, 2024, 8, Downloaded from https://onlinelibrary.wiley.com/doi/10.1002/smkt.202301283 by Shandong University Library, Wiley Online Library on [18/02/2026]. See the Terms and Conditions (https://onlinelibrary.wiley.com/terms-and-conditions) on Wiley Online Library for rules of use; OA articles are governed by the applicable Creative Commons License.", "bbox": [1154, 30, 1171, 1534], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "23699608, 2024, 8, Downloaded from https://onlinelibrary.wiley.com/doi/10.1002/smkt.202301283 by Shandong University Library, Wiley Online Library on [18/02/2026]. See the Terms and Conditions (https://onlinelibrary.wiley.com/terms-and-conditions) on Wiley Online Library for rules of use; OA articles are governed by the applicable Creative Commons License."}, "layout_signature": {"width": 17, "width_bucket": 25, "height": 1504, "left": 1154, "top": 30, "right": 1171, "bottom": 1534, "x_center": 1162.5, "x_center_bucket": 1150, "y_center": 782.0, "x_ratio": 0.9761, "y_ratio": 0.4997, "width_ratio": 0.0143, "height_ratio": 0.961, "line_count": 1}, "span_signature": {"font_size": 5.03, "font_size_median": 5.03, "font_size_bucket": 5.0, "font_family_norm": "Times-Roman", "bold": false, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_family_anchor", "reading_band_id": "band_136", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 7, "block_id": 0, "raw_label": "header", "raw_order": null, "bbox": [98, 46, 345, 117], "text": "ADVANCED\nSCIENCE NEWS\nwww.advancedsciencenews.com", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["header label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["header label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaSansPro-Bold", "flags": 20, "color": 255, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 0, "page": 7, "raw_label": "header", "text": "ADVANCED\nSCIENCE NEWS\nwww.advancedsciencenews.com", "bbox": [98, 46, 345, 117], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "ADVANCED\nSCIENCE NEWS\nwww.advancedsciencenews.com"}, "layout_signature": {"width": 247, "width_bucket": 250, "height": 71, "left": 98, "top": 46, "right": 345, "bottom": 117, "x_center": 221.5, "x_center_bucket": 225, "y_center": 81.5, "x_ratio": 0.186, "y_ratio": 0.0521, "width_ratio": 0.2074, "height_ratio": 0.0454, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaSansPro-Bold", "bold": true, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 7, "block_id": 1, "raw_label": "header", "raw_order": null, "bbox": [1003, 37, 1095, 97], "text": "small methods", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["header label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["header label"], "span_metadata": null, "raw_observation": {"block_id": 1, "page": 7, "raw_label": "header", "text": "small methods", "bbox": [1003, 37, 1095, 97], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "short_fragment", "raw_marker": "small methods", "number": null, "kind": "short_fragment", "normalized_text": "small methods"}, "layout_signature": {"width": 92, "width_bucket": 100, "height": 60, "left": 1003, "top": 37, "right": 1095, "bottom": 97, "x_center": 1049.0, "x_center_bucket": 1050, "y_center": 67.0, "x_ratio": 0.8808, "y_ratio": 0.0428, "width_ratio": 0.0772, "height_ratio": 0.0383, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": true, "_container_bbox": [1005.7522789906125, 37.836628863963085, 1084.0337389451988, 91.04600210547972], "_container_text": "small methods", "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_142", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.6, "decision": "structured_insert_candidate", "evidence": ["visual_container", "narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 7, "block_id": 2, "raw_label": "header", "raw_order": null, "bbox": [902, 97, 1096, 117], "text": "www.small-methods.com", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["header label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["header label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaSansPro-Bold", "flags": 20, "color": 255, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 2, "page": 7, "raw_label": "header", "text": "www.small-methods.com", "bbox": [902, 97, 1096, 117], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "www.small-methods.com"}, "layout_signature": {"width": 194, "width_bucket": 200, "height": 20, "left": 902, "top": 97, "right": 1096, "bottom": 117, "x_center": 999.0, "x_center_bucket": 1000, "y_center": 107.0, "x_ratio": 0.8388, "y_ratio": 0.0684, "width_ratio": 0.1629, "height_ratio": 0.0128, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaSansPro-Bold", "bold": true, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_142", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 7, "block_id": 3, "raw_label": "text", "raw_order": 1, "bbox": [95, 149, 588, 633], "text": "deliver bone-forming peptide-1. $ ^{[63]} $ A thermo-sensitive alginate/ $ \\beta $-TCP/aspirin hydrogel with an interconnected porous microstructure fabricated by Fang et al. was implanted into the periosteum of rat cranial bone, and the results suggested that the formation of new bone was promoted. $ ^{[64]} $ Furthermore, alginate has been combined with other polymers and ceramics, such as collagen, gelatin, and BGs, to enhance its osteogenic differentiation ability, cell adhesion, and mechanical strength. Nevertheless, current research indicates that Alginate has some drawbacks in bone regeneration and repair. For example, alginate has low bioactivity, which is not conducive to the proliferation and differentiation of bone cells. In addition, alginate has a slow degradation rate, which may affect bone tissue regeneration and repair. Modifying alginate's physicochemical properties and constructing scaffold materials that deliver different bioactive substances can improve its performance and enhance its application prospects in clinical settings. For instance, adjusting alginate's molecular weight, structure, and chemical modification can enhance its bioactivity and biodegradability; blending alginate with other biomaterials or combining alginate with drugs or other bioactive substances also can improve its bioactivity and biodegradability.", "page_width": 1191, "page_height": 1565, "role": "body_paragraph", "role_confidence": 0.6, "evidence": ["default body_paragraph for text label"], "seed_role": "body_paragraph", "seed_confidence": 0.6, "seed_evidence": ["default body_paragraph for text label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "STIXMath-Italic", "flags": 6, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 3, "page": 7, "raw_label": "text", "text": "deliver bone-forming peptide-1. $ ^{[63]} $ A thermo-sensitive alginate/ $ \\beta $-TCP/aspirin hydrogel with an interconnected porous microstructure fabricated by Fang et al. was implanted into the periosteum of rat cranial bone, and the results suggested that the formation of new bone was promoted. $ ^{[64]} $ Furthermore, alginate has been combined with other polymers and ceramics, such as collagen, gelatin, and BGs, to enhance its osteogenic differentiation ability, cell adhesion, and mechanical strength. Nevertheless, current research indicates that Alginate has some drawbacks in bone regeneration and repair. For example, alginate has low bioactivity, which is not conducive to the proliferation and differentiation of bone cells. In addition, alginate has a slow degradation rate, which may affect bone tissue regeneration and repair. Modifying alginate's physicochemical properties and constructing scaffold materials that deliver different bioactive substances can improve its performance and enhance its application prospects in clinical settings. For instance, adjusting alginate's molecular weight, structure, and chemical modification can enhance its bioactivity and biodegradability; blending alginate with other biomaterials or combining alginate with drugs or other bioactive substances also can improve its bioactivity and biodegradability.", "bbox": [95, 149, 588, 633], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "deliver bone-forming peptide-1. $ ^{[63]} $ A thermo-sensitive alginate/ $ \\beta $-TCP/aspirin hydrogel with an interconnected porous microstructure fabricated by Fang et al. was implanted into the periosteum of rat cranial bone, and the results suggested that the formation of new bone was promoted. $ ^{[64]} $ Furthermore, alginate has been combined with other polymers and ceramics, such as collagen, gelatin, and BGs, to enhance its osteogenic differentiation ability, cell adhesion, and mechanical strength. Nevertheless, current research indicates that Alginate has some drawbacks in bone regeneration and repair. For example, alginate has low bioactivity, which is not conducive to the proliferation and differentiation of bone cells. In addition, alginate has a slow degradation rate, which may affect bone tissue regeneration and repair. Modifying alginate's physicochemical properties and constructing scaffold materials that deliver different bioactive substances can improve its performance and enhance its application prospects in clinical settings. For instance, adjusting alginate's molecular weight, structure, and chemical modification can enhance its bioactivity and biodegradability; blending alginate with other biomaterials or combining alginate with drugs or other bioactive substances also can improve its bioactivity and biodegradability."}, "layout_signature": {"width": 493, "width_bucket": 500, "height": 484, "left": 95, "top": 149, "right": 588, "bottom": 633, "x_center": 341.5, "x_center_bucket": 350, "y_center": 391.0, "x_ratio": 0.2867, "y_ratio": 0.2498, "width_ratio": 0.4139, "height_ratio": 0.3093, "line_count": 1}, "span_signature": {"font_size": 8.89, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaPro-Regular", "bold": false, "italic": true, "span_count": 228}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_139", "display_cluster_candidate_id": "disp_27_0", "layout_region": "display_zone", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 7, "block_id": 4, "raw_label": "text", "raw_order": 2, "bbox": [96, 633, 587, 1268], "text": "Hyaluronic acid (HA) is an important component of the ECM in the human body, and its interaction with cluster of differentiation 44 (CD44) may regulate cell motility and adhesion. $ ^{[65]} $ Bioactive proteins or drugs can bind to HA through covalent binding or reverse-charged interactions, and HA can be used as a coating material on metal surfaces. $ ^{[66]} $ Various HA-based scaffolds have been investigated to improve stem cell proliferation, adhesion, viability, vascularization, and osteogenic differentiation, indicating that HA plays an important role in bone repair and regeneration. Although HA has a limited role in promoting bone formation, its synergy with other biomaterials or bioactive factors is widely employed in bone tissue engineering. For instance, 3D-printed gelatin/HA/HAP composite scaffold could facilitate cell proliferation and osteogenic differentiation, and the biomineralized composite scaffolds significantly affected cell biological activity. $ ^{[67]} $ The combination of CaP cement with HA also improved the viability and growth rate of human bone marrow MSCs suitable for bone substitution. $ ^{[68]} $ HAP/HA hydrogels loaded with BMP-2 could sustainably deliver osteogenic factors, further facilitating the formation of the bone matrix and inducing bone maturation. $ ^{[69]} $ Low bioactivity and slow degradation rate influence its role in bone repair. Novel strategies need to be explored to improve the performance of HA and enhance its application prospects in bone regeneration and repair. For instance, developing novel HA-based composite materials to enhance their bioactivity and biodegradability; exploring the possibility of using HA-based hydrogels as exosome delivery systems for osteogenic differentiation; in addition, investigating the use of HA-based hydrogels as scaffolds for bone tissue engineering.", "page_width": 1191, "page_height": 1565, "role": "body_paragraph", "role_confidence": 0.6, "evidence": ["default body_paragraph for text label"], "seed_role": "body_paragraph", "seed_confidence": 0.6, "seed_evidence": ["default body_paragraph for text label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 4, "page": 7, "raw_label": "text", "text": "Hyaluronic acid (HA) is an important component of the ECM in the human body, and its interaction with cluster of differentiation 44 (CD44) may regulate cell motility and adhesion. $ ^{[65]} $ Bioactive proteins or drugs can bind to HA through covalent binding or reverse-charged interactions, and HA can be used as a coating material on metal surfaces. $ ^{[66]} $ Various HA-based scaffolds have been investigated to improve stem cell proliferation, adhesion, viability, vascularization, and osteogenic differentiation, indicating that HA plays an important role in bone repair and regeneration. Although HA has a limited role in promoting bone formation, its synergy with other biomaterials or bioactive factors is widely employed in bone tissue engineering. For instance, 3D-printed gelatin/HA/HAP composite scaffold could facilitate cell proliferation and osteogenic differentiation, and the biomineralized composite scaffolds significantly affected cell biological activity. $ ^{[67]} $ The combination of CaP cement with HA also improved the viability and growth rate of human bone marrow MSCs suitable for bone substitution. $ ^{[68]} $ HAP/HA hydrogels loaded with BMP-2 could sustainably deliver osteogenic factors, further facilitating the formation of the bone matrix and inducing bone maturation. $ ^{[69]} $ Low bioactivity and slow degradation rate influence its role in bone repair. Novel strategies need to be explored to improve the performance of HA and enhance its application prospects in bone regeneration and repair. For instance, developing novel HA-based composite materials to enhance their bioactivity and biodegradability; exploring the possibility of using HA-based hydrogels as exosome delivery systems for osteogenic differentiation; in addition, investigating the use of HA-based hydrogels as scaffolds for bone tissue engineering.", "bbox": [96, 633, 587, 1268], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "Hyaluronic acid (HA) is an important component of the ECM in the human body, and its interaction with cluster of differentiation 44 (CD44) may regulate cell motility and adhesion. $ ^{[65]} $ Bioactive proteins or drugs can bind to HA through covalent binding or reverse-charged interactions, and HA can be used as a coating material on metal surfaces. $ ^{[66]} $ Various HA-based scaffolds have been investigated to improve stem cell proliferation, adhesion, viability, vascularization, and osteogenic differentiation, indicating that HA plays an important role in bone repair and regeneration. Although HA has a limited role in promoting bone formation, its synergy with other biomaterials or bioactive factors is widely employed in bone tissue engineering. For instance, 3D-printed gelatin/HA/HAP composite scaffold could facilitate cell proliferation and osteogenic differentiation, and the biomineralized composite scaffolds significantly affected cell biological activity. $ ^{[67]} $ The combination of CaP cement with HA also improved the viability and growth rate of human bone marrow MSCs suitable for bone substitution. $ ^{[68]} $ HAP/HA hydrogels loaded with BMP-2 could sustainably deliver osteogenic factors, further facilitating the formation of the bone matrix and inducing bone maturation. $ ^{[69]} $ Low bioactivity and slow degradation rate influence its role in bone repair. Novel strategies need to be explored to improve the performance of HA and enhance its application prospects in bone regeneration and repair. For instance, developing novel HA-based composite materials to enhance their bioactivity and biodegradability; exploring the possibility of using HA-based hydrogels as exosome delivery systems for osteogenic differentiation; in addition, investigating the use of HA-based hydrogels as scaffolds for bone tissue engineering."}, "layout_signature": {"width": 491, "width_bucket": 500, "height": 635, "left": 96, "top": 633, "right": 587, "bottom": 1268, "x_center": 341.5, "x_center_bucket": 350, "y_center": 950.5, "x_ratio": 0.2867, "y_ratio": 0.6073, "width_ratio": 0.4123, "height_ratio": 0.4058, "line_count": 1}, "span_signature": {"font_size": 8.79, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaPro-Regular", "bold": false, "italic": true, "span_count": 248}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_140", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 7, "block_id": 5, "raw_label": "text", "raw_order": 3, "bbox": [95, 1266, 588, 1445], "text": "Collagen is the most abundant protein in bone ECM, and type I collagen is the most ubiquitous among $ \\approx $29 types of collagen, especially in bone tissues. $ ^{[70]} $ Collagen is a fibrous protein that is the main component of connective tissue in mammals. Collagen is the most extensively used bone biomaterial owing to its inferior antigenicity and excellent physicochemical properties. Collagen can be modified by crosslinking its functional groups with biomolecules to fabricate various bone materials with specific mechanical and biological properties. Collagen can be applied to bone tissue engineering in different physical forms, such as scaffolds, hydrogels, sponges, films, micro-and nanospheres, and composites, to promote stem cell attachment, proliferation, motility, differentiation, and osteogenesis. Heo et al. found that MSC/human umbilical vein endothelial cell spheroids encapsulated in a collagen/fibrin hydrogel significantly improved cell viability and proliferation, promoted osteogenic differentiation, induced pre-vascular formation, and increased bone mineral deposition compared with an MSC-suspension. $ ^{[71]} $ Chen et al. reported that dexamethasone incorporated into collagen/BCP scaffolds was released sustainably, and the composite exhibited enhanced osteogenic differentiation of MSCs in vitro and promoted the formation of new bone tissue in vivo. $ ^{[72]} $ Furthermore, However, weak mechanical strength, high costs of manufacturing, rapid degradability, and risk of infection limit the clinical applications of collagen. Although collagen has some disadvantages, it is still an indispensable part of bone regeneration and repair. Researchers are working hard to find ways to solve these problems so that the advantages of collagen can be better utilized while minimizing the impact of its disadvantages. Degradation rate of collagen can be adjusted by changing its physical and chemical properties to improve its effect in bone repair. In addition, collagen can be used in combination with other biomaterials to further improve its effect in bone repair. For example, collagen can be combined with inorganic substances such as HAP to manufacture bone repair materials with better mechanical properties.", "page_width": 1191, "page_height": 1565, "role": "body_paragraph", "role_confidence": 0.6, "evidence": ["default body_paragraph for text label"], "seed_role": "body_paragraph", "seed_confidence": 0.6, "seed_evidence": ["default body_paragraph for text label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "STIX-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "STIX-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 5, "page": 7, "raw_label": "text", "text": "Collagen is the most abundant protein in bone ECM, and type I collagen is the most ubiquitous among $ \\approx $29 types of collagen, especially in bone tissues. $ ^{[70]} $ Collagen is a fibrous protein that is the main component of connective tissue in mammals. Collagen is the most extensively used bone biomaterial owing to its inferior antigenicity and excellent physicochemical properties. Collagen can be modified by crosslinking its functional groups with biomolecules to fabricate various bone materials with specific mechanical and biological properties. Collagen can be applied to bone tissue engineering in different physical forms, such as scaffolds, hydrogels, sponges, films, micro-and nanospheres, and composites, to promote stem cell attachment, proliferation, motility, differentiation, and osteogenesis. Heo et al. found that MSC/human umbilical vein endothelial cell spheroids encapsulated in a collagen/fibrin hydrogel significantly improved cell viability and proliferation, promoted osteogenic differentiation, induced pre-vascular formation, and increased bone mineral deposition compared with an MSC-suspension. $ ^{[71]} $ Chen et al. reported that dexamethasone incorporated into collagen/BCP scaffolds was released sustainably, and the composite exhibited enhanced osteogenic differentiation of MSCs in vitro and promoted the formation of new bone tissue in vivo. $ ^{[72]} $ Furthermore, However, weak mechanical strength, high costs of manufacturing, rapid degradability, and risk of infection limit the clinical applications of collagen. Although collagen has some disadvantages, it is still an indispensable part of bone regeneration and repair. Researchers are working hard to find ways to solve these problems so that the advantages of collagen can be better utilized while minimizing the impact of its disadvantages. Degradation rate of collagen can be adjusted by changing its physical and chemical properties to improve its effect in bone repair. In addition, collagen can be used in combination with other biomaterials to further improve its effect in bone repair. For example, collagen can be combined with inorganic substances such as HAP to manufacture bone repair materials with better mechanical properties.", "bbox": [95, 1266, 588, 1445], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "Collagen is the most abundant protein in bone ECM, and type I collagen is the most ubiquitous among $ \\approx $29 types of collagen, especially in bone tissues. $ ^{[70]} $ Collagen is a fibrous protein that is the main component of connective tissue in mammals. Collagen is the most extensively used bone biomaterial owing to its inferior antigenicity and excellent physicochemical properties. Collagen can be modified by crosslinking its functional groups with biomolecules to fabricate various bone materials with specific mechanical and biological properties. Collagen can be applied to bone tissue engineering in different physical forms, such as scaffolds, hydrogels, sponges, films, micro-and nanospheres, and composites, to promote stem cell attachment, proliferation, motility, differentiation, and osteogenesis. Heo et al. found that MSC/human umbilical vein endothelial cell spheroids encapsulated in a collagen/fibrin hydrogel significantly improved cell viability and proliferation, promoted osteogenic differentiation, induced pre-vascular formation, and increased bone mineral deposition compared with an MSC-suspension. $ ^{[71]} $ Chen et al. reported that dexamethasone incorporated into collagen/BCP scaffolds was released sustainably, and the composite exhibited enhanced osteogenic differentiation of MSCs in vitro and promoted the formation of new bone tissue in vivo. $ ^{[72]} $ Furthermore, However, weak mechanical strength, high costs of manufacturing, rapid degradability, and risk of infection limit the clinical applications of collagen. Although collagen has some disadvantages, it is still an indispensable part of bone regeneration and repair. Researchers are working hard to find ways to solve these problems so that the advantages of collagen can be better utilized while minimizing the impact of its disadvantages. Degradation rate of collagen can be adjusted by changing its physical and chemical properties to improve its effect in bone repair. In addition, collagen can be used in combination with other biomaterials to further improve its effect in bone repair. For example, collagen can be combined with inorganic substances such as HAP to manufacture bone repair materials with better mechanical properties."}, "layout_signature": {"width": 493, "width_bucket": 500, "height": 179, "left": 95, "top": 1266, "right": 588, "bottom": 1445, "x_center": 341.5, "x_center_bucket": 350, "y_center": 1355.5, "x_ratio": 0.2867, "y_ratio": 0.8661, "width_ratio": 0.4139, "height_ratio": 0.1144, "line_count": 1}, "span_signature": {"font_size": 8.89, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaPro-Regular", "bold": false, "italic": true, "span_count": 111}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_139", "display_cluster_candidate_id": "disp_27_0", "layout_region": "display_zone", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 7, "block_id": 6, "raw_label": "text", "raw_order": 4, "bbox": [604, 148, 1099, 742], "text": "", "page_width": 1191, "page_height": 1565, "role": "ocr_text_missing", "role_confidence": 0.8, "evidence": ["ocr detected text region (raw_label=text) but no text extracted; no pdf backfill available"], "seed_role": "ocr_text_missing", "seed_confidence": 0.8, "seed_evidence": ["ocr detected text region (raw_label=text) but no text extracted; no pdf backfill available"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 6, "page": 7, "raw_label": "text", "text": "", "bbox": [604, 148, 1099, 742], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "empty", "raw_marker": null, "number": null, "kind": null, "normalized_text": ""}, "layout_signature": {"width": 495, "width_bucket": 500, "height": 594, "left": 604, "top": 148, "right": 1099, "bottom": 742, "x_center": 851.5, "x_center_bucket": 850, "y_center": 445.0, "x_ratio": 0.7149, "y_ratio": 0.2843, "width_ratio": 0.4156, "height_ratio": 0.3796, "line_count": 1}, "span_signature": {"font_size": 8.87, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaPro-Regular", "bold": false, "italic": true, "span_count": 191}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": "pdf_text_layer_fallback_rejected", "_ocr_raw_status": "missing_text_rejected", "_ocr_raw_error_type": "backfill_overlaps_existing_text_block", "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "_needs_pdf_fallback": true, "reading_band_id": "band_140", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 7, "block_id": 7, "raw_label": "text", "raw_order": 5, "bbox": [604, 742, 1098, 1311], "text": "Gelatin is derived from the degradation of type I collagen. Gelatin has biologically functional arginine–glycine–aspartate-binding sequences that improve cell adhesion, differentiation, and proliferation. $ ^{[73,74]} $ The porous surface of the HA-loaded gelatin/alginate hydrogel with high order, homogeneity, and size restriction provided an osteogenic platform for the interaction and cooperation between bone marrow-derived stem cells and macrophages. Effective communication between the macrophages and bone marrow-derived stem cells accounted for the remarkable performance of the composite in healing critical-sized skull bone defects. $ ^{[75]} $ Gelatin–chitosan–BG composite scaffolds prepared by Dasgupta et al. could promote the proliferation and osteogenic differentiation of MSCs and accelerate new bone formation in a rabbit tibia model. $ ^{[76]} $ A macroporous composite scaffold comprising of gelatin and BGs fabricated by Thomas et al. displayed a good apatite-forming capability, cell adhesion properties, and enhanced compressive strength and osteogenesis. $ ^{[77]} $ While gelatin possesses good biocompatibility, biodegradability, and low antigenicity, its poor mechanical properties and high degradability limit its application in bone tissue engineering. However, gelatin can be chemically modified to achieve better therapeutic effects in bone repair. It has been reported that gelatin hydrogels loaded with growth factors could promote bone repair and regeneration. $ ^{[78]} $ Physical and chemical properties of collagen can be changed to adjust its degradation rate, thereby improving its effect in bone repair.", "page_width": 1191, "page_height": 1565, "role": "body_paragraph", "role_confidence": 0.6, "evidence": ["default body_paragraph for text label"], "seed_role": "body_paragraph", "seed_confidence": 0.6, "seed_evidence": ["default body_paragraph for text label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 7, "page": 7, "raw_label": "text", "text": "Gelatin is derived from the degradation of type I collagen. Gelatin has biologically functional arginine–glycine–aspartate-binding sequences that improve cell adhesion, differentiation, and proliferation. $ ^{[73,74]} $ The porous surface of the HA-loaded gelatin/alginate hydrogel with high order, homogeneity, and size restriction provided an osteogenic platform for the interaction and cooperation between bone marrow-derived stem cells and macrophages. Effective communication between the macrophages and bone marrow-derived stem cells accounted for the remarkable performance of the composite in healing critical-sized skull bone defects. $ ^{[75]} $ Gelatin–chitosan–BG composite scaffolds prepared by Dasgupta et al. could promote the proliferation and osteogenic differentiation of MSCs and accelerate new bone formation in a rabbit tibia model. $ ^{[76]} $ A macroporous composite scaffold comprising of gelatin and BGs fabricated by Thomas et al. displayed a good apatite-forming capability, cell adhesion properties, and enhanced compressive strength and osteogenesis. $ ^{[77]} $ While gelatin possesses good biocompatibility, biodegradability, and low antigenicity, its poor mechanical properties and high degradability limit its application in bone tissue engineering. However, gelatin can be chemically modified to achieve better therapeutic effects in bone repair. It has been reported that gelatin hydrogels loaded with growth factors could promote bone repair and regeneration. $ ^{[78]} $ Physical and chemical properties of collagen can be changed to adjust its degradation rate, thereby improving its effect in bone repair.", "bbox": [604, 742, 1098, 1311], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "Gelatin is derived from the degradation of type I collagen. Gelatin has biologically functional arginine–glycine–aspartate-binding sequences that improve cell adhesion, differentiation, and proliferation. $ ^{[73,74]} $ The porous surface of the HA-loaded gelatin/alginate hydrogel with high order, homogeneity, and size restriction provided an osteogenic platform for the interaction and cooperation between bone marrow-derived stem cells and macrophages. Effective communication between the macrophages and bone marrow-derived stem cells accounted for the remarkable performance of the composite in healing critical-sized skull bone defects. $ ^{[75]} $ Gelatin–chitosan–BG composite scaffolds prepared by Dasgupta et al. could promote the proliferation and osteogenic differentiation of MSCs and accelerate new bone formation in a rabbit tibia model. $ ^{[76]} $ A macroporous composite scaffold comprising of gelatin and BGs fabricated by Thomas et al. displayed a good apatite-forming capability, cell adhesion properties, and enhanced compressive strength and osteogenesis. $ ^{[77]} $ While gelatin possesses good biocompatibility, biodegradability, and low antigenicity, its poor mechanical properties and high degradability limit its application in bone tissue engineering. However, gelatin can be chemically modified to achieve better therapeutic effects in bone repair. It has been reported that gelatin hydrogels loaded with growth factors could promote bone repair and regeneration. $ ^{[78]} $ Physical and chemical properties of collagen can be changed to adjust its degradation rate, thereby improving its effect in bone repair."}, "layout_signature": {"width": 494, "width_bucket": 500, "height": 569, "left": 604, "top": 742, "right": 1098, "bottom": 1311, "x_center": 851.0, "x_center_bucket": 850, "y_center": 1026.5, "x_ratio": 0.7145, "y_ratio": 0.6559, "width_ratio": 0.4148, "height_ratio": 0.3636, "line_count": 1}, "span_signature": {"font_size": 8.82, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaPro-Regular", "bold": false, "italic": true, "span_count": 303}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_139", "display_cluster_candidate_id": "disp_27_0", "layout_region": "display_zone", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 7, "block_id": 8, "raw_label": "text", "raw_order": 6, "bbox": [604, 1310, 1098, 1445], "text": "Silk fibroin is a sustainable and biocompatible fibrous polymer with high mechanical strength that is suitable for use as a bone biomaterial. The degradation rate of silk fibroin-based biomaterials can be controlled to match bone regeneration. $ ^{[79]} $ Silk fibroin has been molded into hydrogels, composite scaffolds, and films for bone-regenerative applications. Although the low", "page_width": 1191, "page_height": 1565, "role": "body_paragraph", "role_confidence": 0.6, "evidence": ["default body_paragraph for text label"], "seed_role": "body_paragraph", "seed_confidence": 0.6, "seed_evidence": ["default body_paragraph for text label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 8, "page": 7, "raw_label": "text", "text": "Silk fibroin is a sustainable and biocompatible fibrous polymer with high mechanical strength that is suitable for use as a bone biomaterial. The degradation rate of silk fibroin-based biomaterials can be controlled to match bone regeneration. $ ^{[79]} $ Silk fibroin has been molded into hydrogels, composite scaffolds, and films for bone-regenerative applications. Although the low", "bbox": [604, 1310, 1098, 1445], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "Silk fibroin is a sustainable and biocompatible fibrous polymer with high mechanical strength that is suitable for use as a bone biomaterial. The degradation rate of silk fibroin-based biomaterials can be controlled to match bone regeneration. $ ^{[79]} $ Silk fibroin has been molded into hydrogels, composite scaffolds, and films for bone-regenerative applications. Although the low"}, "layout_signature": {"width": 494, "width_bucket": 500, "height": 135, "left": 604, "top": 1310, "right": 1098, "bottom": 1445, "x_center": 851.0, "x_center_bucket": 850, "y_center": 1377.5, "x_ratio": 0.7145, "y_ratio": 0.8802, "width_ratio": 0.4148, "height_ratio": 0.0863, "line_count": 1}, "span_signature": {"font_size": 8.87, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaPro-Regular", "bold": false, "italic": true, "span_count": 91}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_140", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 7, "block_id": 9, "raw_label": "footer", "raw_order": null, "bbox": [99, 1487, 289, 1505], "text": "Small Methods 2024, 8, 2301283", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["footer label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["footer label"], "span_metadata": [{"size": 6.973800182342529, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 9, "page": 7, "raw_label": "footer", "text": "Small Methods 2024, 8, 2301283", "bbox": [99, 1487, 289, 1505], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "Small Methods 2024, 8, 2301283"}, "layout_signature": {"width": 190, "width_bucket": 200, "height": 18, "left": 99, "top": 1487, "right": 289, "bottom": 1505, "x_center": 194.0, "x_center_bucket": 200, "y_center": 1496.0, "x_ratio": 0.1629, "y_ratio": 0.9559, "width_ratio": 0.1595, "height_ratio": 0.0115, "line_count": 1}, "span_signature": {"font_size": 6.97, "font_size_median": 6.97, "font_size_bucket": 7.0, "font_family_norm": "ScalaSansPro-Italic", "bold": true, "italic": true, "span_count": 5}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_138", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 7, "block_id": 10, "raw_label": "footer", "raw_order": null, "bbox": [530, 1484, 665, 1508], "text": "2301283 (7 of 27)", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["footer label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["footer label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaSansPro-Bold", "flags": 20, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 10, "page": 7, "raw_label": "footer", "text": "2301283 (7 of 27)", "bbox": [530, 1484, 665, 1508], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_dot", "raw_marker": "2301283", "number": 2301283, "kind": "reference", "normalized_text": "2301283 (7 of 27)"}, "layout_signature": {"width": 135, "width_bucket": 125, "height": 24, "left": 530, "top": 1484, "right": 665, "bottom": 1508, "x_center": 597.5, "x_center_bucket": 600, "y_center": 1496.0, "x_ratio": 0.5017, "y_ratio": 0.9559, "width_ratio": 0.1134, "height_ratio": 0.0153, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaSansPro-Bold", "bold": true, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_141", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "hard", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 7, "block_id": 11, "raw_label": "footer", "raw_order": null, "bbox": [937, 1487, 1096, 1506], "text": "© 2024 Wiley-VCH GmbH", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["footer label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["footer label"], "span_metadata": [{"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 11, "page": 7, "raw_label": "footer", "text": "© 2024 Wiley-VCH GmbH", "bbox": [937, 1487, 1096, 1506], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "© 2024 Wiley-VCH GmbH"}, "layout_signature": {"width": 159, "width_bucket": 150, "height": 19, "left": 937, "top": 1487, "right": 1096, "bottom": 1506, "x_center": 1016.5, "x_center_bucket": 1025, "y_center": 1496.5, "x_ratio": 0.8535, "y_ratio": 0.9562, "width_ratio": 0.1335, "height_ratio": 0.0121, "line_count": 1}, "span_signature": {"font_size": 6.97, "font_size_median": 6.97, "font_size_bucket": 7.0, "font_family_norm": "ScalaSansPro-Regular", "bold": false, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_142", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 7, "block_id": 12, "raw_label": "aside_text", "raw_order": null, "bbox": [1154, 31, 1171, 1534], "text": "23699608, 2024, 8, Downloaded from https://onlinelibrary.wiley.com/doi/10.1002/smld.202301283 by Shandong University Library, Wiley Online Library on [18/02/2026]. See the Terms and Conditions (https://onlinelibrary.wiley.com/terms-and-conditions) on Wiley Online Library for rules of use; OA articles are governed by the applicable Creative Commons License", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.95, "evidence": ["margin-band narrow/tall geometry; treated as noise"], "seed_role": "noise", "seed_confidence": 0.95, "seed_evidence": ["margin-band narrow/tall geometry; treated as noise"], "span_metadata": [{"size": 5.03000020980835, "font": "Times-Roman", "flags": 4, "color": 0, "dir": [0.0, 1.0], "wmode": 0}], "raw_observation": {"block_id": 12, "page": 7, "raw_label": "aside_text", "text": "23699608, 2024, 8, Downloaded from https://onlinelibrary.wiley.com/doi/10.1002/smld.202301283 by Shandong University Library, Wiley Online Library on [18/02/2026]. See the Terms and Conditions (https://onlinelibrary.wiley.com/terms-and-conditions) on Wiley Online Library for rules of use; OA articles are governed by the applicable Creative Commons License", "bbox": [1154, 31, 1171, 1534], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "23699608, 2024, 8, Downloaded from https://onlinelibrary.wiley.com/doi/10.1002/smld.202301283 by Shandong University Library, Wiley Online Library on [18/02/2026]. See the Terms and Conditions (https://onlinelibrary.wiley.com/terms-and-conditions) on Wiley Online Library for rules of use; OA articles are governed by the applicable Creative Commons License"}, "layout_signature": {"width": 17, "width_bucket": 25, "height": 1503, "left": 1154, "top": 31, "right": 1171, "bottom": 1534, "x_center": 1162.5, "x_center_bucket": 1150, "y_center": 782.5, "x_ratio": 0.9761, "y_ratio": 0.5, "width_ratio": 0.0143, "height_ratio": 0.9604, "line_count": 1}, "span_signature": {"font_size": 5.03, "font_size_median": 5.03, "font_size_bucket": 5.0, "font_family_norm": "Times-Roman", "bold": false, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_family_anchor", "reading_band_id": "band_142", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 8, "block_id": 0, "raw_label": "header", "raw_order": null, "bbox": [92, 46, 339, 116], "text": "ADVANCED\nSCIENCE NEWS\nwww.advancedsciencenews.com", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["header label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["header label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaSansPro-Bold", "flags": 20, "color": 255, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 0, "page": 8, "raw_label": "header", "text": "ADVANCED\nSCIENCE NEWS\nwww.advancedsciencenews.com", "bbox": [92, 46, 339, 116], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "ADVANCED\nSCIENCE NEWS\nwww.advancedsciencenews.com"}, "layout_signature": {"width": 247, "width_bucket": 250, "height": 70, "left": 92, "top": 46, "right": 339, "bottom": 116, "x_center": 215.5, "x_center_bucket": 225, "y_center": 81.0, "x_ratio": 0.1809, "y_ratio": 0.0518, "width_ratio": 0.2074, "height_ratio": 0.0447, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaSansPro-Bold", "bold": true, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 8, "block_id": 1, "raw_label": "header_image", "raw_order": null, "bbox": [997, 37, 1089, 97], "text": "", "page_width": 1191, "page_height": 1565, "role": "unknown_structural", "role_confidence": 0.2, "evidence": ["unrecognized label 'header_image'"], "seed_role": "unknown_structural", "seed_confidence": 0.2, "seed_evidence": ["unrecognized label 'header_image'"], "span_metadata": null, "raw_observation": {"block_id": 1, "page": 8, "raw_label": "header_image", "text": "", "bbox": [997, 37, 1089, 97], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "empty", "raw_marker": null, "number": null, "kind": null, "normalized_text": ""}, "layout_signature": {"width": 92, "width_bucket": 100, "height": 60, "left": 997, "top": 37, "right": 1089, "bottom": 97, "x_center": 1043.0, "x_center_bucket": 1050, "y_center": 67.0, "x_ratio": 0.8757, "y_ratio": 0.0428, "width_ratio": 0.0772, "height_ratio": 0.0383, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": true, "zone": "body_zone", "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_142", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["non-structural role accepted"]}
+{"paper_id": "2HEUD5P9", "page": 8, "block_id": 2, "raw_label": "header", "raw_order": null, "bbox": [897, 97, 1090, 116], "text": "www.small-methods.com", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["header label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["header label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaSansPro-Bold", "flags": 20, "color": 255, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 2, "page": 8, "raw_label": "header", "text": "www.small-methods.com", "bbox": [897, 97, 1090, 116], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "www.small-methods.com"}, "layout_signature": {"width": 193, "width_bucket": 200, "height": 19, "left": 897, "top": 97, "right": 1090, "bottom": 116, "x_center": 993.5, "x_center_bucket": 1000, "y_center": 106.5, "x_ratio": 0.8342, "y_ratio": 0.0681, "width_ratio": 0.162, "height_ratio": 0.0121, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaSansPro-Bold", "bold": true, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_142", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 8, "block_id": 3, "raw_label": "text", "raw_order": 1, "bbox": [90, 149, 582, 678], "text": "osteogenesis of silk fibroin limits its application in bone repair, it can promote new bone formation when combined with other biomaterials. For instance, a silk fibroin/chitosan/HAP composite combined with autologous concentrated growth factors significantly promoted the adhesion, proliferation, and osteogenic differentiation of bone marrow MSCs and efficiently repaired bone defects in a rabbit radius-critical bone defect model. $ ^{[80]} $ The 3D-printed mesoporous BG/silk fibroin composite scaffold showed good biocompatibility, superior compressive strength, and stimulated bone regeneration compared with mesoporous BG/PCL composite scaffolds. $ ^{[81]} $ In recent years, researchers have improved silk fibroin's mechanical properties and bioactivity by modifying and compounding it, thereby expanding its application in bone tissue engineering. For instance, researchers can compound silk fibroin with other materials such as hydroxyapatite and nanocarbon fibers to prepare composite materials with excellent mechanical properties and bioactivity for bone regeneration and repair. Additionally, researchers can regulate silk fibroin's mechanical properties and bioactivity by changing its structure and morphology, such as its molecular weight and cross-linking. Overall, silk fibroin has potential application value in bone regeneration and repair, but further research and improvement are needed to meet the mechanical demands and bioactivity of bone tissue.", "page_width": 1191, "page_height": 1565, "role": "body_paragraph", "role_confidence": 0.6, "evidence": ["default body_paragraph for text label"], "seed_role": "body_paragraph", "seed_confidence": 0.6, "seed_evidence": ["default body_paragraph for text label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 3, "page": 8, "raw_label": "text", "text": "osteogenesis of silk fibroin limits its application in bone repair, it can promote new bone formation when combined with other biomaterials. For instance, a silk fibroin/chitosan/HAP composite combined with autologous concentrated growth factors significantly promoted the adhesion, proliferation, and osteogenic differentiation of bone marrow MSCs and efficiently repaired bone defects in a rabbit radius-critical bone defect model. $ ^{[80]} $ The 3D-printed mesoporous BG/silk fibroin composite scaffold showed good biocompatibility, superior compressive strength, and stimulated bone regeneration compared with mesoporous BG/PCL composite scaffolds. $ ^{[81]} $ In recent years, researchers have improved silk fibroin's mechanical properties and bioactivity by modifying and compounding it, thereby expanding its application in bone tissue engineering. For instance, researchers can compound silk fibroin with other materials such as hydroxyapatite and nanocarbon fibers to prepare composite materials with excellent mechanical properties and bioactivity for bone regeneration and repair. Additionally, researchers can regulate silk fibroin's mechanical properties and bioactivity by changing its structure and morphology, such as its molecular weight and cross-linking. Overall, silk fibroin has potential application value in bone regeneration and repair, but further research and improvement are needed to meet the mechanical demands and bioactivity of bone tissue.", "bbox": [90, 149, 582, 678], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "osteogenesis of silk fibroin limits its application in bone repair, it can promote new bone formation when combined with other biomaterials. For instance, a silk fibroin/chitosan/HAP composite combined with autologous concentrated growth factors significantly promoted the adhesion, proliferation, and osteogenic differentiation of bone marrow MSCs and efficiently repaired bone defects in a rabbit radius-critical bone defect model. $ ^{[80]} $ The 3D-printed mesoporous BG/silk fibroin composite scaffold showed good biocompatibility, superior compressive strength, and stimulated bone regeneration compared with mesoporous BG/PCL composite scaffolds. $ ^{[81]} $ In recent years, researchers have improved silk fibroin's mechanical properties and bioactivity by modifying and compounding it, thereby expanding its application in bone tissue engineering. For instance, researchers can compound silk fibroin with other materials such as hydroxyapatite and nanocarbon fibers to prepare composite materials with excellent mechanical properties and bioactivity for bone regeneration and repair. Additionally, researchers can regulate silk fibroin's mechanical properties and bioactivity by changing its structure and morphology, such as its molecular weight and cross-linking. Overall, silk fibroin has potential application value in bone regeneration and repair, but further research and improvement are needed to meet the mechanical demands and bioactivity of bone tissue."}, "layout_signature": {"width": 492, "width_bucket": 500, "height": 529, "left": 90, "top": 149, "right": 582, "bottom": 678, "x_center": 336.0, "x_center_bucket": 325, "y_center": 413.5, "x_ratio": 0.2821, "y_ratio": 0.2642, "width_ratio": 0.4131, "height_ratio": 0.338, "line_count": 1}, "span_signature": {"font_size": 8.9, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaPro-Regular", "bold": false, "italic": true, "span_count": 270}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_139", "display_cluster_candidate_id": "disp_27_0", "layout_region": "display_zone", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 8, "block_id": 4, "raw_label": "paragraph_title", "raw_order": 2, "bbox": [92, 720, 279, 743], "text": "2.2.2. Synthetic Polymers", "page_width": 1191, "page_height": 1565, "role": "sub_subsection_heading", "role_confidence": 0.85, "evidence": ["paragraph_title label with numbering: 2.2.2. Synthetic Polymers"], "seed_role": "sub_subsection_heading", "seed_confidence": 0.85, "seed_evidence": ["paragraph_title label with numbering: 2.2.2. Synthetic Polymers"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaSansPro-Italic", "flags": 6, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 4, "page": 8, "raw_label": "paragraph_title", "text": "2.2.2. Synthetic Polymers", "bbox": [92, 720, 279, 743], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "heading_numbered", "raw_marker": "2.2.2", "number": "2.2.2", "kind": "heading", "normalized_text": "2.2.2. Synthetic Polymers"}, "layout_signature": {"width": 187, "width_bucket": 175, "height": 23, "left": 92, "top": 720, "right": 279, "bottom": 743, "x_center": 185.5, "x_center_bucket": 175, "y_center": 731.5, "x_ratio": 0.1558, "y_ratio": 0.4674, "width_ratio": 0.157, "height_ratio": 0.0147, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaSansPro-Italic", "bold": false, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_140", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 8, "block_id": 5, "raw_label": "text", "raw_order": 3, "bbox": [90, 763, 581, 895], "text": "Polycaprolactone (PCL), polyglycolic acid (PGA), polylactic acid (PLA), and their copolymers are US Food and Drug Administration (FDA) approved polyesters that are extensively used in bone repair and regeneration. Lactic acid and glycolic acid are degradation products of these synthetic polymers in the human body and are therefore excreted by natural metabolism.", "page_width": 1191, "page_height": 1565, "role": "body_paragraph", "role_confidence": 0.6, "evidence": ["default body_paragraph for text label"], "seed_role": "body_paragraph", "seed_confidence": 0.6, "seed_evidence": ["default body_paragraph for text label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 5, "page": 8, "raw_label": "text", "text": "Polycaprolactone (PCL), polyglycolic acid (PGA), polylactic acid (PLA), and their copolymers are US Food and Drug Administration (FDA) approved polyesters that are extensively used in bone repair and regeneration. Lactic acid and glycolic acid are degradation products of these synthetic polymers in the human body and are therefore excreted by natural metabolism.", "bbox": [90, 763, 581, 895], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "Polycaprolactone (PCL), polyglycolic acid (PGA), polylactic acid (PLA), and their copolymers are US Food and Drug Administration (FDA) approved polyesters that are extensively used in bone repair and regeneration. Lactic acid and glycolic acid are degradation products of these synthetic polymers in the human body and are therefore excreted by natural metabolism."}, "layout_signature": {"width": 491, "width_bucket": 500, "height": 132, "left": 90, "top": 763, "right": 581, "bottom": 895, "x_center": 335.5, "x_center_bucket": 325, "y_center": 829.0, "x_ratio": 0.2817, "y_ratio": 0.5297, "width_ratio": 0.4123, "height_ratio": 0.0843, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaPro-Regular", "bold": false, "italic": true, "span_count": 36}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_139", "display_cluster_candidate_id": "disp_27_0", "layout_region": "display_zone", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 8, "block_id": 6, "raw_label": "text", "raw_order": 4, "bbox": [89, 895, 582, 1446], "text": "PLA is characterized by cytocompatibility, non-toxic degradation products, and thermal stability. $ ^{[82,83]} $ Grémare et al. reported that the cell viability and metabolic activity of human bone marrow stromal cells cultured on 3D-printed PLA scaffolds with different pore sizes, biodegradability, and sufficient mechanical integrity were not affected. $ ^{[84]} $ The composites of PLA and other polymers or ceramics exhibit both osteoconductivity and osteoinductivity. A 3D-printed PLA/HAP scaffold with microvascular mimicking channels and bone-formation-supporting structures showed enhanced cell proliferation, adhesion, osteogenesis, and vascular cell growth. $ ^{[85]} $ Electrospun nanofibrous meshes comprising PLA and gelatin enhanced the osteogenic differentiation of MSCs sheets and increased new calcified bone formation within rat cranial defects. $ ^{[86]} $ Meng et al. synthesized a biomimetic reinforced composite scaffold combining the poly L-lactic acid (PLLA) lattice with gelatin/genipin/bioglass hydrogel, the composite scaffold shows excellent interconnectivity, high storage modulus and improved storage modulus (Figure 3A–C). $ ^{[87]} $ However, the slow biodegradation rate of PLA may lead to chronic inflammation and tissue necrosis. To overcome these issues, researchers have begun exploring PLA modification and compounding. For example, researchers have successfully compounded PLA with other materials such as hydroxyapatite and nanocarbon fibers to improve its bioactivity and mechanical properties. Additionally, researchers can regulate PLA's biodegradation rate and mechanical properties by changing its structure and morphology, such as its molecular weight and cross-linking.", "page_width": 1191, "page_height": 1565, "role": "body_paragraph", "role_confidence": 0.6, "evidence": ["default body_paragraph for text label"], "seed_role": "body_paragraph", "seed_confidence": 0.6, "seed_evidence": ["default body_paragraph for text label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Bold", "flags": 20, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Bold", "flags": 20, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 6, "page": 8, "raw_label": "text", "text": "PLA is characterized by cytocompatibility, non-toxic degradation products, and thermal stability. $ ^{[82,83]} $ Grémare et al. reported that the cell viability and metabolic activity of human bone marrow stromal cells cultured on 3D-printed PLA scaffolds with different pore sizes, biodegradability, and sufficient mechanical integrity were not affected. $ ^{[84]} $ The composites of PLA and other polymers or ceramics exhibit both osteoconductivity and osteoinductivity. A 3D-printed PLA/HAP scaffold with microvascular mimicking channels and bone-formation-supporting structures showed enhanced cell proliferation, adhesion, osteogenesis, and vascular cell growth. $ ^{[85]} $ Electrospun nanofibrous meshes comprising PLA and gelatin enhanced the osteogenic differentiation of MSCs sheets and increased new calcified bone formation within rat cranial defects. $ ^{[86]} $ Meng et al. synthesized a biomimetic reinforced composite scaffold combining the poly L-lactic acid (PLLA) lattice with gelatin/genipin/bioglass hydrogel, the composite scaffold shows excellent interconnectivity, high storage modulus and improved storage modulus (Figure 3A–C). $ ^{[87]} $ However, the slow biodegradation rate of PLA may lead to chronic inflammation and tissue necrosis. To overcome these issues, researchers have begun exploring PLA modification and compounding. For example, researchers have successfully compounded PLA with other materials such as hydroxyapatite and nanocarbon fibers to improve its bioactivity and mechanical properties. Additionally, researchers can regulate PLA's biodegradation rate and mechanical properties by changing its structure and morphology, such as its molecular weight and cross-linking.", "bbox": [89, 895, 582, 1446], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "PLA is characterized by cytocompatibility, non-toxic degradation products, and thermal stability. $ ^{[82,83]} $ Grémare et al. reported that the cell viability and metabolic activity of human bone marrow stromal cells cultured on 3D-printed PLA scaffolds with different pore sizes, biodegradability, and sufficient mechanical integrity were not affected. $ ^{[84]} $ The composites of PLA and other polymers or ceramics exhibit both osteoconductivity and osteoinductivity. A 3D-printed PLA/HAP scaffold with microvascular mimicking channels and bone-formation-supporting structures showed enhanced cell proliferation, adhesion, osteogenesis, and vascular cell growth. $ ^{[85]} $ Electrospun nanofibrous meshes comprising PLA and gelatin enhanced the osteogenic differentiation of MSCs sheets and increased new calcified bone formation within rat cranial defects. $ ^{[86]} $ Meng et al. synthesized a biomimetic reinforced composite scaffold combining the poly L-lactic acid (PLLA) lattice with gelatin/genipin/bioglass hydrogel, the composite scaffold shows excellent interconnectivity, high storage modulus and improved storage modulus (Figure 3A–C). $ ^{[87]} $ However, the slow biodegradation rate of PLA may lead to chronic inflammation and tissue necrosis. To overcome these issues, researchers have begun exploring PLA modification and compounding. For example, researchers have successfully compounded PLA with other materials such as hydroxyapatite and nanocarbon fibers to improve its bioactivity and mechanical properties. Additionally, researchers can regulate PLA's biodegradation rate and mechanical properties by changing its structure and morphology, such as its molecular weight and cross-linking."}, "layout_signature": {"width": 493, "width_bucket": 500, "height": 551, "left": 89, "top": 895, "right": 582, "bottom": 1446, "x_center": 335.5, "x_center_bucket": 325, "y_center": 1170.5, "x_ratio": 0.2817, "y_ratio": 0.7479, "width_ratio": 0.4139, "height_ratio": 0.3521, "line_count": 1}, "span_signature": {"font_size": 8.78, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaPro-Regular", "bold": true, "italic": true, "span_count": 242}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_140", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 8, "block_id": 7, "raw_label": "text", "raw_order": 5, "bbox": [600, 149, 1091, 214], "text": "", "page_width": 1191, "page_height": 1565, "role": "ocr_text_missing", "role_confidence": 0.8, "evidence": ["ocr detected text region (raw_label=text) but no text extracted; no pdf backfill available"], "seed_role": "ocr_text_missing", "seed_confidence": 0.8, "seed_evidence": ["ocr detected text region (raw_label=text) but no text extracted; no pdf backfill available"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 7, "page": 8, "raw_label": "text", "text": "", "bbox": [600, 149, 1091, 214], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "empty", "raw_marker": null, "number": null, "kind": null, "normalized_text": ""}, "layout_signature": {"width": 491, "width_bucket": 500, "height": 65, "left": 600, "top": 149, "right": 1091, "bottom": 214, "x_center": 845.5, "x_center_bucket": 850, "y_center": 181.5, "x_ratio": 0.7099, "y_ratio": 0.116, "width_ratio": 0.4123, "height_ratio": 0.0415, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaPro-Regular", "bold": false, "italic": true, "span_count": 33}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": "pdf_text_layer_fallback_rejected", "_ocr_raw_status": "missing_text_rejected", "_ocr_raw_error_type": "backfill_overlaps_existing_text_block", "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "_needs_pdf_fallback": true, "reading_band_id": "band_139", "display_cluster_candidate_id": "disp_27_0", "layout_region": "display_zone", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 8, "block_id": 8, "raw_label": "text", "raw_order": 6, "bbox": [598, 213, 1093, 1049], "text": "PGA has a high tensile modulus and porosity and can be easily manipulated and manufactured into various shapes. $ ^{[88]} $ However, its rapid degradation rate, low mechanical strength, and acidic degradation products, which lead to a severe inflammatory response, restrict its bone regenerative applications. $ ^{[89]} $ PGA is often used in combination with PLGA for bone repair. PLGA is the most widespread synthetic polymer biomaterial and has good biocompatibility and degradation rate tunability by varying the proportion of copolymers. The in situ tissue engineering scaffold (iTE-scaffold) effectively promoted the angiogenesis of periodontal ligament stem cells (PDLSCs) and induced macrophage polarization into pro-healing M2 phenotype to modulate inflammation (Figure 3D,E). $ ^{[90]} $ PLGA/HAP composite fibrous scaffolds exhibit enhanced hydrophilicity via polydopamine modification, and the polydopamine coating effectively immobilized BMP-2 on the composites. PLGA/HAP composite fibrous scaffolds promoted cell proliferation and attachment and increased ALP activity and calcium deposition. $ ^{[91]} $ PLGA-HAP porous scaffolds printed in a reproductive manner are biocompatible, have high cell viability, and promote osteogenic differentiation in vitro. Moreover, there was limited inflammation after implantation of 3D-printed PLGA-HAP porous scaffolds in vivo. $ ^{[92]} $ PLGA/chitosan microspheres possessed stronger compressive strength, more sustained drug release, and increased cell proliferation and mineralization than PLGA alone. $ ^{[93]} $ However, its suboptimal mechanical properties, poor cell adhesion, and osteoinductivity limit its application in bone tissue engineering. Furthermore, PLGA's degradation products are acidic, which may cause acidification of surrounding tissues and affect bone repair and regeneration. The degradation rate of PLGA is affected by various factors, such as molecular weight, copolymer ratio, crystallinity, etc., which may lead to its unstable degradation rate. The preparation methods of PLGA are subject to certain limitations, such as the solvent evaporation method only being applicable to prepare films, while the melt extrusion method is applicable to prepare 3D scaffolds. Future research should focus on addressing these shortcomings to further improve the application of PLGA in bone tissue engineering.", "page_width": 1191, "page_height": 1565, "role": "body_paragraph", "role_confidence": 0.6, "evidence": ["default body_paragraph for text label"], "seed_role": "body_paragraph", "seed_confidence": 0.6, "seed_evidence": ["default body_paragraph for text label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 8, "page": 8, "raw_label": "text", "text": "PGA has a high tensile modulus and porosity and can be easily manipulated and manufactured into various shapes. $ ^{[88]} $ However, its rapid degradation rate, low mechanical strength, and acidic degradation products, which lead to a severe inflammatory response, restrict its bone regenerative applications. $ ^{[89]} $ PGA is often used in combination with PLGA for bone repair. PLGA is the most widespread synthetic polymer biomaterial and has good biocompatibility and degradation rate tunability by varying the proportion of copolymers. The in situ tissue engineering scaffold (iTE-scaffold) effectively promoted the angiogenesis of periodontal ligament stem cells (PDLSCs) and induced macrophage polarization into pro-healing M2 phenotype to modulate inflammation (Figure 3D,E). $ ^{[90]} $ PLGA/HAP composite fibrous scaffolds exhibit enhanced hydrophilicity via polydopamine modification, and the polydopamine coating effectively immobilized BMP-2 on the composites. PLGA/HAP composite fibrous scaffolds promoted cell proliferation and attachment and increased ALP activity and calcium deposition. $ ^{[91]} $ PLGA-HAP porous scaffolds printed in a reproductive manner are biocompatible, have high cell viability, and promote osteogenic differentiation in vitro. Moreover, there was limited inflammation after implantation of 3D-printed PLGA-HAP porous scaffolds in vivo. $ ^{[92]} $ PLGA/chitosan microspheres possessed stronger compressive strength, more sustained drug release, and increased cell proliferation and mineralization than PLGA alone. $ ^{[93]} $ However, its suboptimal mechanical properties, poor cell adhesion, and osteoinductivity limit its application in bone tissue engineering. Furthermore, PLGA's degradation products are acidic, which may cause acidification of surrounding tissues and affect bone repair and regeneration. The degradation rate of PLGA is affected by various factors, such as molecular weight, copolymer ratio, crystallinity, etc., which may lead to its unstable degradation rate. The preparation methods of PLGA are subject to certain limitations, such as the solvent evaporation method only being applicable to prepare films, while the melt extrusion method is applicable to prepare 3D scaffolds. Future research should focus on addressing these shortcomings to further improve the application of PLGA in bone tissue engineering.", "bbox": [598, 213, 1093, 1049], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "PGA has a high tensile modulus and porosity and can be easily manipulated and manufactured into various shapes. $ ^{[88]} $ However, its rapid degradation rate, low mechanical strength, and acidic degradation products, which lead to a severe inflammatory response, restrict its bone regenerative applications. $ ^{[89]} $ PGA is often used in combination with PLGA for bone repair. PLGA is the most widespread synthetic polymer biomaterial and has good biocompatibility and degradation rate tunability by varying the proportion of copolymers. The in situ tissue engineering scaffold (iTE-scaffold) effectively promoted the angiogenesis of periodontal ligament stem cells (PDLSCs) and induced macrophage polarization into pro-healing M2 phenotype to modulate inflammation (Figure 3D,E). $ ^{[90]} $ PLGA/HAP composite fibrous scaffolds exhibit enhanced hydrophilicity via polydopamine modification, and the polydopamine coating effectively immobilized BMP-2 on the composites. PLGA/HAP composite fibrous scaffolds promoted cell proliferation and attachment and increased ALP activity and calcium deposition. $ ^{[91]} $ PLGA-HAP porous scaffolds printed in a reproductive manner are biocompatible, have high cell viability, and promote osteogenic differentiation in vitro. Moreover, there was limited inflammation after implantation of 3D-printed PLGA-HAP porous scaffolds in vivo. $ ^{[92]} $ PLGA/chitosan microspheres possessed stronger compressive strength, more sustained drug release, and increased cell proliferation and mineralization than PLGA alone. $ ^{[93]} $ However, its suboptimal mechanical properties, poor cell adhesion, and osteoinductivity limit its application in bone tissue engineering. Furthermore, PLGA's degradation products are acidic, which may cause acidification of surrounding tissues and affect bone repair and regeneration. The degradation rate of PLGA is affected by various factors, such as molecular weight, copolymer ratio, crystallinity, etc., which may lead to its unstable degradation rate. The preparation methods of PLGA are subject to certain limitations, such as the solvent evaporation method only being applicable to prepare films, while the melt extrusion method is applicable to prepare 3D scaffolds. Future research should focus on addressing these shortcomings to further improve the application of PLGA in bone tissue engineering."}, "layout_signature": {"width": 495, "width_bucket": 500, "height": 836, "left": 598, "top": 213, "right": 1093, "bottom": 1049, "x_center": 845.5, "x_center_bucket": 850, "y_center": 631.0, "x_ratio": 0.7099, "y_ratio": 0.4032, "width_ratio": 0.4156, "height_ratio": 0.5342, "line_count": 1}, "span_signature": {"font_size": 8.78, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaPro-Regular", "bold": false, "italic": true, "span_count": 282}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_140", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 8, "block_id": 9, "raw_label": "text", "raw_order": 7, "bbox": [598, 1049, 1093, 1446], "text": "PCL is an aliphatic polymer, consisting of hexanoate units, and has high crystallinity, easily manipulable mechanical characteristics, and good biocompatibility. Lin et al. reported that the PCL/cobalt-substituted HAP composite decreased the crystallinity of the PCL membrane, which led to greater degradation, promoted cell proliferation of osteoblasts, and increased calcium deposition compared to pure PCL membranes. $ ^{[94]} $ Torres et al. found that PCL scaffolds with an average roughness of 0.93 $ \\mu $m promoted the expression of the osteogenic markers and mineralization in the absence of dexamethasone. $ ^{[95]} $ Jang et al. entrapped HA in PCL/HA hybrid microspheres, and the data revealed that PCL/HA hybrid microspheres promoted the proliferation and osteogenic differentiation of human periosteum-derived cells and accelerated bone regeneration in vivo. $ ^{[96]} $ The fabricated bioactive calcium silicate nanowires reinforced poly (e-caprolactone) (CS-PCL) composite electrospun fibrous membranes (EFMs) could promote bone regeneration both in vitro and in vivo (Figure 3F–K). $ ^{[97]} $ However, its relatively slow", "page_width": 1191, "page_height": 1565, "role": "body_paragraph", "role_confidence": 0.6, "evidence": ["default body_paragraph for text label"], "seed_role": "body_paragraph", "seed_confidence": 0.6, "seed_evidence": ["default body_paragraph for text label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "STIX-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 9, "page": 8, "raw_label": "text", "text": "PCL is an aliphatic polymer, consisting of hexanoate units, and has high crystallinity, easily manipulable mechanical characteristics, and good biocompatibility. Lin et al. reported that the PCL/cobalt-substituted HAP composite decreased the crystallinity of the PCL membrane, which led to greater degradation, promoted cell proliferation of osteoblasts, and increased calcium deposition compared to pure PCL membranes. $ ^{[94]} $ Torres et al. found that PCL scaffolds with an average roughness of 0.93 $ \\mu $m promoted the expression of the osteogenic markers and mineralization in the absence of dexamethasone. $ ^{[95]} $ Jang et al. entrapped HA in PCL/HA hybrid microspheres, and the data revealed that PCL/HA hybrid microspheres promoted the proliferation and osteogenic differentiation of human periosteum-derived cells and accelerated bone regeneration in vivo. $ ^{[96]} $ The fabricated bioactive calcium silicate nanowires reinforced poly (e-caprolactone) (CS-PCL) composite electrospun fibrous membranes (EFMs) could promote bone regeneration both in vitro and in vivo (Figure 3F–K). $ ^{[97]} $ However, its relatively slow", "bbox": [598, 1049, 1093, 1446], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "PCL is an aliphatic polymer, consisting of hexanoate units, and has high crystallinity, easily manipulable mechanical characteristics, and good biocompatibility. Lin et al. reported that the PCL/cobalt-substituted HAP composite decreased the crystallinity of the PCL membrane, which led to greater degradation, promoted cell proliferation of osteoblasts, and increased calcium deposition compared to pure PCL membranes. $ ^{[94]} $ Torres et al. found that PCL scaffolds with an average roughness of 0.93 $ \\mu $m promoted the expression of the osteogenic markers and mineralization in the absence of dexamethasone. $ ^{[95]} $ Jang et al. entrapped HA in PCL/HA hybrid microspheres, and the data revealed that PCL/HA hybrid microspheres promoted the proliferation and osteogenic differentiation of human periosteum-derived cells and accelerated bone regeneration in vivo. $ ^{[96]} $ The fabricated bioactive calcium silicate nanowires reinforced poly (e-caprolactone) (CS-PCL) composite electrospun fibrous membranes (EFMs) could promote bone regeneration both in vitro and in vivo (Figure 3F–K). $ ^{[97]} $ However, its relatively slow"}, "layout_signature": {"width": 495, "width_bucket": 500, "height": 397, "left": 598, "top": 1049, "right": 1093, "bottom": 1446, "x_center": 845.5, "x_center_bucket": 850, "y_center": 1247.5, "x_ratio": 0.7099, "y_ratio": 0.7971, "width_ratio": 0.4156, "height_ratio": 0.2537, "line_count": 1}, "span_signature": {"font_size": 8.83, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaPro-Regular", "bold": false, "italic": true, "span_count": 263}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_138", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 8, "block_id": 10, "raw_label": "footer", "raw_order": null, "bbox": [94, 1487, 283, 1505], "text": "Small Methods 2024, 8, 2301283", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["footer label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["footer label"], "span_metadata": [{"size": 6.973800182342529, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 10, "page": 8, "raw_label": "footer", "text": "Small Methods 2024, 8, 2301283", "bbox": [94, 1487, 283, 1505], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "Small Methods 2024, 8, 2301283"}, "layout_signature": {"width": 189, "width_bucket": 200, "height": 18, "left": 94, "top": 1487, "right": 283, "bottom": 1505, "x_center": 188.5, "x_center_bucket": 200, "y_center": 1496.0, "x_ratio": 0.1583, "y_ratio": 0.9559, "width_ratio": 0.1587, "height_ratio": 0.0115, "line_count": 1}, "span_signature": {"font_size": 6.97, "font_size_median": 6.97, "font_size_bucket": 7.0, "font_family_norm": "ScalaSansPro-Italic", "bold": true, "italic": true, "span_count": 5}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_141", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "hard", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 8, "block_id": 11, "raw_label": "number", "raw_order": null, "bbox": [524, 1484, 658, 1507], "text": "2301283 (8 of 27)", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["page number label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["page number label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaSansPro-Bold", "flags": 20, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 11, "page": 8, "raw_label": "number", "text": "2301283 (8 of 27)", "bbox": [524, 1484, 658, 1507], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_dot", "raw_marker": "2301283", "number": 2301283, "kind": "reference", "normalized_text": "2301283 (8 of 27)"}, "layout_signature": {"width": 134, "width_bucket": 125, "height": 23, "left": 524, "top": 1484, "right": 658, "bottom": 1507, "x_center": 591.0, "x_center_bucket": 600, "y_center": 1495.5, "x_ratio": 0.4962, "y_ratio": 0.9556, "width_ratio": 0.1125, "height_ratio": 0.0147, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaSansPro-Bold", "bold": true, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_142", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 8, "block_id": 12, "raw_label": "footer", "raw_order": null, "bbox": [931, 1487, 1090, 1506], "text": "© 2024 Wiley-VCH GmbH", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["footer label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["footer label"], "span_metadata": [{"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 12, "page": 8, "raw_label": "footer", "text": "© 2024 Wiley-VCH GmbH", "bbox": [931, 1487, 1090, 1506], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "© 2024 Wiley-VCH GmbH"}, "layout_signature": {"width": 159, "width_bucket": 150, "height": 19, "left": 931, "top": 1487, "right": 1090, "bottom": 1506, "x_center": 1010.5, "x_center_bucket": 1000, "y_center": 1496.5, "x_ratio": 0.8484, "y_ratio": 0.9562, "width_ratio": 0.1335, "height_ratio": 0.0121, "line_count": 1}, "span_signature": {"font_size": 6.97, "font_size_median": 6.97, "font_size_bucket": 7.0, "font_family_norm": "ScalaSansPro-Regular", "bold": false, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_142", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 8, "block_id": 13, "raw_label": "aside_text", "raw_order": null, "bbox": [1154, 30, 1171, 1533], "text": "23699608, 2024, 8, Downloaded from https://onlinelibrary.wiley.com/doi/10.1002/smkt.202301283 by Shandong University Library, Wiley Online Library on [18/02/2026]. See the Terms and Conditions (https://onlinelibrary.wiley.com/terms-and-conditions) on Wiley Online Library for rules of use; OA articles are governed by the applicable Creative Commons License.", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.95, "evidence": ["margin-band narrow/tall geometry; treated as noise"], "seed_role": "noise", "seed_confidence": 0.95, "seed_evidence": ["margin-band narrow/tall geometry; treated as noise"], "span_metadata": [{"size": 5.03000020980835, "font": "Times-Roman", "flags": 4, "color": 0, "dir": [0.0, 1.0], "wmode": 0}], "raw_observation": {"block_id": 13, "page": 8, "raw_label": "aside_text", "text": "23699608, 2024, 8, Downloaded from https://onlinelibrary.wiley.com/doi/10.1002/smkt.202301283 by Shandong University Library, Wiley Online Library on [18/02/2026]. See the Terms and Conditions (https://onlinelibrary.wiley.com/terms-and-conditions) on Wiley Online Library for rules of use; OA articles are governed by the applicable Creative Commons License.", "bbox": [1154, 30, 1171, 1533], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "23699608, 2024, 8, Downloaded from https://onlinelibrary.wiley.com/doi/10.1002/smkt.202301283 by Shandong University Library, Wiley Online Library on [18/02/2026]. See the Terms and Conditions (https://onlinelibrary.wiley.com/terms-and-conditions) on Wiley Online Library for rules of use; OA articles are governed by the applicable Creative Commons License."}, "layout_signature": {"width": 17, "width_bucket": 25, "height": 1503, "left": 1154, "top": 30, "right": 1171, "bottom": 1533, "x_center": 1162.5, "x_center_bucket": 1150, "y_center": 781.5, "x_ratio": 0.9761, "y_ratio": 0.4994, "width_ratio": 0.0143, "height_ratio": 0.9604, "line_count": 1}, "span_signature": {"font_size": 5.03, "font_size_median": 5.03, "font_size_bucket": 5.0, "font_family_norm": "Times-Roman", "bold": false, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_family_anchor", "reading_band_id": "band_136", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 9, "block_id": 0, "raw_label": "header", "raw_order": null, "bbox": [98, 45, 345, 117], "text": "ADVANCED\nSCIENCE NEWS\nwww.advancedsciencenews.com", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["header label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["header label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaSansPro-Bold", "flags": 20, "color": 255, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 0, "page": 9, "raw_label": "header", "text": "ADVANCED\nSCIENCE NEWS\nwww.advancedsciencenews.com", "bbox": [98, 45, 345, 117], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "ADVANCED\nSCIENCE NEWS\nwww.advancedsciencenews.com"}, "layout_signature": {"width": 247, "width_bucket": 250, "height": 72, "left": 98, "top": 45, "right": 345, "bottom": 117, "x_center": 221.5, "x_center_bucket": 225, "y_center": 81.0, "x_ratio": 0.186, "y_ratio": 0.0518, "width_ratio": 0.2074, "height_ratio": 0.046, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaSansPro-Bold", "bold": true, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 9, "block_id": 1, "raw_label": "header", "raw_order": null, "bbox": [901, 36, 1097, 117], "text": "small methods\nwww.small-methods.com", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["header label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["header label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaSansPro-Bold", "flags": 20, "color": 255, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 1, "page": 9, "raw_label": "header", "text": "small methods\nwww.small-methods.com", "bbox": [901, 36, 1097, 117], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "small methods\nwww.small-methods.com"}, "layout_signature": {"width": 196, "width_bucket": 200, "height": 81, "left": 901, "top": 36, "right": 1097, "bottom": 117, "x_center": 999.0, "x_center_bucket": 1000, "y_center": 76.5, "x_ratio": 0.8388, "y_ratio": 0.0489, "width_ratio": 0.1646, "height_ratio": 0.0518, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaSansPro-Bold", "bold": true, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_142", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 9, "block_id": 2, "raw_label": "figure_title", "raw_order": null, "bbox": [103, 155, 137, 181], "text": "(A)", "page_width": 1191, "page_height": 1565, "role": "figure_inner_text", "role_confidence": 0.9, "evidence": ["panel label / figure inner text: (A)"], "seed_role": "figure_inner_text", "seed_confidence": 0.9, "seed_evidence": ["panel label / figure inner text: (A)"], "span_metadata": null, "raw_observation": {"block_id": 2, "page": 9, "raw_label": "figure_title", "text": "(A)", "bbox": [103, 155, 137, 181], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "panel_label", "raw_marker": "(A)", "number": null, "kind": "panel_label", "normalized_text": "(A)"}, "layout_signature": {"width": 34, "width_bucket": 25, "height": 26, "left": 103, "top": 155, "right": 137, "bottom": 181, "x_center": 120.0, "x_center_bucket": 125, "y_center": 168.0, "x_ratio": 0.1008, "y_ratio": 0.1073, "width_ratio": 0.0285, "height_ratio": 0.0166, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "display_zone", "style_family": "legend_like", "style_family_authority": "figure_marker", "reading_band_id": "band_142", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 9, "block_id": 3, "raw_label": "image", "raw_order": null, "bbox": [149, 158, 346, 306], "text": "", "page_width": 1191, "page_height": 1565, "role": "figure_asset", "role_confidence": 0.85, "evidence": ["media label: image"], "seed_role": "media_asset", "seed_confidence": 0.85, "seed_evidence": ["media label: image"], "span_metadata": null, "raw_observation": {"block_id": 3, "page": 9, "raw_label": "image", "text": "", "bbox": [149, 158, 346, 306], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "empty", "raw_marker": null, "number": null, "kind": null, "normalized_text": ""}, "layout_signature": {"width": 197, "width_bucket": 200, "height": 148, "left": 149, "top": 158, "right": 346, "bottom": 306, "x_center": 247.5, "x_center_bucket": 250, "y_center": 232.0, "x_ratio": 0.2078, "y_ratio": 0.1482, "width_ratio": 0.1654, "height_ratio": 0.0946, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_139", "display_cluster_candidate_id": "disp_27_0", "layout_region": "display_zone", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"], "asset_family_hint": "figure_like", "asset_family_confidence": 0.7, "asset_family_evidence": ["raw_label:image"]}
+{"paper_id": "2HEUD5P9", "page": 9, "block_id": 4, "raw_label": "image", "raw_order": null, "bbox": [340, 157, 575, 315], "text": "", "page_width": 1191, "page_height": 1565, "role": "figure_asset", "role_confidence": 0.85, "evidence": ["media label: image"], "seed_role": "media_asset", "seed_confidence": 0.85, "seed_evidence": ["media label: image"], "span_metadata": null, "raw_observation": {"block_id": 4, "page": 9, "raw_label": "image", "text": "", "bbox": [340, 157, 575, 315], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "empty", "raw_marker": null, "number": null, "kind": null, "normalized_text": ""}, "layout_signature": {"width": 235, "width_bucket": 225, "height": 158, "left": 340, "top": 157, "right": 575, "bottom": 315, "x_center": 457.5, "x_center_bucket": 450, "y_center": 236.0, "x_ratio": 0.3841, "y_ratio": 0.1508, "width_ratio": 0.1973, "height_ratio": 0.101, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_140", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"], "asset_family_hint": "figure_like", "asset_family_confidence": 0.7, "asset_family_evidence": ["raw_label:image"]}
+{"paper_id": "2HEUD5P9", "page": 9, "block_id": 5, "raw_label": "image", "raw_order": null, "bbox": [569, 155, 834, 328], "text": "", "page_width": 1191, "page_height": 1565, "role": "figure_asset", "role_confidence": 0.85, "evidence": ["media label: image"], "seed_role": "media_asset", "seed_confidence": 0.85, "seed_evidence": ["media label: image"], "span_metadata": null, "raw_observation": {"block_id": 5, "page": 9, "raw_label": "image", "text": "", "bbox": [569, 155, 834, 328], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "empty", "raw_marker": null, "number": null, "kind": null, "normalized_text": ""}, "layout_signature": {"width": 265, "width_bucket": 275, "height": 173, "left": 569, "top": 155, "right": 834, "bottom": 328, "x_center": 701.5, "x_center_bucket": 700, "y_center": 241.5, "x_ratio": 0.589, "y_ratio": 0.1543, "width_ratio": 0.2225, "height_ratio": 0.1105, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_139", "display_cluster_candidate_id": "disp_27_0", "layout_region": "display_zone", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"], "asset_family_hint": "figure_like", "asset_family_confidence": 0.7, "asset_family_evidence": ["raw_label:image"]}
+{"paper_id": "2HEUD5P9", "page": 9, "block_id": 6, "raw_label": "image", "raw_order": null, "bbox": [846, 157, 1080, 351], "text": "", "page_width": 1191, "page_height": 1565, "role": "figure_asset", "role_confidence": 0.85, "evidence": ["media label: image"], "seed_role": "media_asset", "seed_confidence": 0.85, "seed_evidence": ["media label: image"], "span_metadata": null, "raw_observation": {"block_id": 6, "page": 9, "raw_label": "image", "text": "", "bbox": [846, 157, 1080, 351], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "empty", "raw_marker": null, "number": null, "kind": null, "normalized_text": ""}, "layout_signature": {"width": 234, "width_bucket": 225, "height": 194, "left": 846, "top": 157, "right": 1080, "bottom": 351, "x_center": 963.0, "x_center_bucket": 975, "y_center": 254.0, "x_ratio": 0.8086, "y_ratio": 0.1623, "width_ratio": 0.1965, "height_ratio": 0.124, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_140", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"], "asset_family_hint": "figure_like", "asset_family_confidence": 0.7, "asset_family_evidence": ["raw_label:image"]}
+{"paper_id": "2HEUD5P9", "page": 9, "block_id": 7, "raw_label": "image", "raw_order": null, "bbox": [142, 329, 826, 586], "text": "", "page_width": 1191, "page_height": 1565, "role": "figure_asset", "role_confidence": 0.85, "evidence": ["media label: image"], "seed_role": "media_asset", "seed_confidence": 0.85, "seed_evidence": ["media label: image"], "span_metadata": null, "raw_observation": {"block_id": 7, "page": 9, "raw_label": "image", "text": "", "bbox": [142, 329, 826, 586], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "empty", "raw_marker": null, "number": null, "kind": null, "normalized_text": ""}, "layout_signature": {"width": 684, "width_bucket": 675, "height": 257, "left": 142, "top": 329, "right": 826, "bottom": 586, "x_center": 484.0, "x_center_bucket": 475, "y_center": 457.5, "x_ratio": 0.4064, "y_ratio": 0.2923, "width_ratio": 0.5743, "height_ratio": 0.1642, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_139", "display_cluster_candidate_id": "disp_27_0", "layout_region": "display_zone", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.0, "decision": "body", "evidence": []}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"], "asset_family_hint": "figure_like", "asset_family_confidence": 0.7, "asset_family_evidence": ["raw_label:image"]}
+{"paper_id": "2HEUD5P9", "page": 9, "block_id": 8, "raw_label": "figure_title", "raw_order": null, "bbox": [850, 155, 881, 180], "text": "(B)", "page_width": 1191, "page_height": 1565, "role": "figure_inner_text", "role_confidence": 0.9, "evidence": ["panel label / figure inner text: (B)"], "seed_role": "figure_inner_text", "seed_confidence": 0.9, "seed_evidence": ["panel label / figure inner text: (B)"], "span_metadata": null, "raw_observation": {"block_id": 8, "page": 9, "raw_label": "figure_title", "text": "(B)", "bbox": [850, 155, 881, 180], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "panel_label", "raw_marker": "(B)", "number": null, "kind": "panel_label", "normalized_text": "(B)"}, "layout_signature": {"width": 31, "width_bucket": 25, "height": 25, "left": 850, "top": 155, "right": 881, "bottom": 180, "x_center": 865.5, "x_center_bucket": 875, "y_center": 167.5, "x_ratio": 0.7267, "y_ratio": 0.107, "width_ratio": 0.026, "height_ratio": 0.016, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "display_zone", "style_family": "legend_like", "style_family_authority": "figure_marker", "reading_band_id": "band_140", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 9, "block_id": 9, "raw_label": "figure_title", "raw_order": null, "bbox": [848, 355, 879, 380], "text": "(C)", "page_width": 1191, "page_height": 1565, "role": "figure_inner_text", "role_confidence": 0.9, "evidence": ["panel label / figure inner text: (C)"], "seed_role": "figure_inner_text", "seed_confidence": 0.9, "seed_evidence": ["panel label / figure inner text: (C)"], "span_metadata": null, "raw_observation": {"block_id": 9, "page": 9, "raw_label": "figure_title", "text": "(C)", "bbox": [848, 355, 879, 380], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "panel_label", "raw_marker": "(C)", "number": null, "kind": "panel_label", "normalized_text": "(C)"}, "layout_signature": {"width": 31, "width_bucket": 25, "height": 25, "left": 848, "top": 355, "right": 879, "bottom": 380, "x_center": 863.5, "x_center_bucket": 875, "y_center": 367.5, "x_ratio": 0.725, "y_ratio": 0.2348, "width_ratio": 0.026, "height_ratio": 0.016, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "display_zone", "style_family": "legend_like", "style_family_authority": "figure_marker", "reading_band_id": "band_138", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 9, "block_id": 10, "raw_label": "chart", "raw_order": null, "bbox": [847, 365, 1093, 577], "text": "", "page_width": 1191, "page_height": 1565, "role": "figure_asset", "role_confidence": 0.85, "evidence": ["media label: chart"], "seed_role": "media_asset", "seed_confidence": 0.85, "seed_evidence": ["media label: chart"], "span_metadata": null, "raw_observation": {"block_id": 10, "page": 9, "raw_label": "chart", "text": "", "bbox": [847, 365, 1093, 577], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "empty", "raw_marker": null, "number": null, "kind": null, "normalized_text": ""}, "layout_signature": {"width": 246, "width_bucket": 250, "height": 212, "left": 847, "top": 365, "right": 1093, "bottom": 577, "x_center": 970.0, "x_center_bucket": 975, "y_center": 471.0, "x_ratio": 0.8144, "y_ratio": 0.301, "width_ratio": 0.2065, "height_ratio": 0.1355, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_141", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "hard", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"], "asset_family_hint": "figure_like", "asset_family_confidence": 0.7, "asset_family_evidence": ["raw_label:chart"]}
+{"paper_id": "2HEUD5P9", "page": 9, "block_id": 11, "raw_label": "figure_title", "raw_order": null, "bbox": [109, 596, 140, 621], "text": "(D)", "page_width": 1191, "page_height": 1565, "role": "figure_inner_text", "role_confidence": 0.9, "evidence": ["panel label / figure inner text: (D)"], "seed_role": "figure_inner_text", "seed_confidence": 0.9, "seed_evidence": ["panel label / figure inner text: (D)"], "span_metadata": null, "raw_observation": {"block_id": 11, "page": 9, "raw_label": "figure_title", "text": "(D)", "bbox": [109, 596, 140, 621], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "panel_label", "raw_marker": "(D)", "number": null, "kind": "panel_label", "normalized_text": "(D)"}, "layout_signature": {"width": 31, "width_bucket": 25, "height": 25, "left": 109, "top": 596, "right": 140, "bottom": 621, "x_center": 124.5, "x_center_bucket": 125, "y_center": 608.5, "x_ratio": 0.1045, "y_ratio": 0.3888, "width_ratio": 0.026, "height_ratio": 0.016, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "display_zone", "style_family": "legend_like", "style_family_authority": "figure_marker", "reading_band_id": "band_142", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 9, "block_id": 12, "raw_label": "image", "raw_order": null, "bbox": [128, 602, 475, 849], "text": "", "page_width": 1191, "page_height": 1565, "role": "figure_asset", "role_confidence": 0.85, "evidence": ["media label: image"], "seed_role": "media_asset", "seed_confidence": 0.85, "seed_evidence": ["media label: image"], "span_metadata": null, "raw_observation": {"block_id": 12, "page": 9, "raw_label": "image", "text": "", "bbox": [128, 602, 475, 849], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "empty", "raw_marker": null, "number": null, "kind": null, "normalized_text": ""}, "layout_signature": {"width": 347, "width_bucket": 350, "height": 247, "left": 128, "top": 602, "right": 475, "bottom": 849, "x_center": 301.5, "x_center_bucket": 300, "y_center": 725.5, "x_ratio": 0.2531, "y_ratio": 0.4636, "width_ratio": 0.2914, "height_ratio": 0.1578, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_142", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"], "asset_family_hint": "figure_like", "asset_family_confidence": 0.7, "asset_family_evidence": ["raw_label:image"]}
+{"paper_id": "2HEUD5P9", "page": 9, "block_id": 13, "raw_label": "figure_title", "raw_order": null, "bbox": [491, 607, 522, 628], "text": "(F)", "page_width": 1191, "page_height": 1565, "role": "figure_inner_text", "role_confidence": 0.9, "evidence": ["panel label / figure inner text: (F)"], "seed_role": "figure_inner_text", "seed_confidence": 0.9, "seed_evidence": ["panel label / figure inner text: (F)"], "span_metadata": null, "raw_observation": {"block_id": 13, "page": 9, "raw_label": "figure_title", "text": "(F)", "bbox": [491, 607, 522, 628], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "panel_label", "raw_marker": "(F)", "number": null, "kind": "panel_label", "normalized_text": "(F)"}, "layout_signature": {"width": 31, "width_bucket": 25, "height": 21, "left": 491, "top": 607, "right": 522, "bottom": 628, "x_center": 506.5, "x_center_bucket": 500, "y_center": 617.5, "x_ratio": 0.4253, "y_ratio": 0.3946, "width_ratio": 0.026, "height_ratio": 0.0134, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "display_zone", "style_family": "legend_like", "style_family_authority": "figure_marker", "reading_band_id": "band_136", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 9, "block_id": 14, "raw_label": "image", "raw_order": null, "bbox": [483, 601, 838, 766], "text": "", "page_width": 1191, "page_height": 1565, "role": "figure_asset", "role_confidence": 0.85, "evidence": ["media label: image"], "seed_role": "media_asset", "seed_confidence": 0.85, "seed_evidence": ["media label: image"], "span_metadata": null, "raw_observation": {"block_id": 14, "page": 9, "raw_label": "image", "text": "", "bbox": [483, 601, 838, 766], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "empty", "raw_marker": null, "number": null, "kind": null, "normalized_text": ""}, "layout_signature": {"width": 355, "width_bucket": 350, "height": 165, "left": 483, "top": 601, "right": 838, "bottom": 766, "x_center": 660.5, "x_center_bucket": 650, "y_center": 683.5, "x_ratio": 0.5546, "y_ratio": 0.4367, "width_ratio": 0.2981, "height_ratio": 0.1054, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_136", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"], "asset_family_hint": "figure_like", "asset_family_confidence": 0.7, "asset_family_evidence": ["raw_label:image"]}
+{"paper_id": "2HEUD5P9", "page": 9, "block_id": 15, "raw_label": "figure_title", "raw_order": null, "bbox": [820, 599, 855, 623], "text": "(G)", "page_width": 1191, "page_height": 1565, "role": "figure_inner_text", "role_confidence": 0.9, "evidence": ["panel label / figure inner text: (G)"], "seed_role": "figure_inner_text", "seed_confidence": 0.9, "seed_evidence": ["panel label / figure inner text: (G)"], "span_metadata": null, "raw_observation": {"block_id": 15, "page": 9, "raw_label": "figure_title", "text": "(G)", "bbox": [820, 599, 855, 623], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "panel_label", "raw_marker": "(G)", "number": null, "kind": "panel_label", "normalized_text": "(G)"}, "layout_signature": {"width": 35, "width_bucket": 25, "height": 24, "left": 820, "top": 599, "right": 855, "bottom": 623, "x_center": 837.5, "x_center_bucket": 850, "y_center": 611.0, "x_ratio": 0.7032, "y_ratio": 0.3904, "width_ratio": 0.0294, "height_ratio": 0.0153, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "display_zone", "style_family": "legend_like", "style_family_authority": "figure_marker", "reading_band_id": "band_136", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 9, "block_id": 16, "raw_label": "chart", "raw_order": null, "bbox": [824, 601, 1085, 775], "text": "", "page_width": 1191, "page_height": 1565, "role": "figure_asset", "role_confidence": 0.85, "evidence": ["media label: chart"], "seed_role": "media_asset", "seed_confidence": 0.85, "seed_evidence": ["media label: chart"], "span_metadata": null, "raw_observation": {"block_id": 16, "page": 9, "raw_label": "chart", "text": "", "bbox": [824, 601, 1085, 775], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "empty", "raw_marker": null, "number": null, "kind": null, "normalized_text": ""}, "layout_signature": {"width": 261, "width_bucket": 250, "height": 174, "left": 824, "top": 601, "right": 1085, "bottom": 775, "x_center": 954.5, "x_center_bucket": 950, "y_center": 688.0, "x_ratio": 0.8014, "y_ratio": 0.4396, "width_ratio": 0.2191, "height_ratio": 0.1112, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_136", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"], "asset_family_hint": "figure_like", "asset_family_confidence": 0.7, "asset_family_evidence": ["raw_label:chart"]}
+{"paper_id": "2HEUD5P9", "page": 9, "block_id": 17, "raw_label": "figure_title", "raw_order": null, "bbox": [479, 762, 511, 785], "text": "(H)", "page_width": 1191, "page_height": 1565, "role": "figure_inner_text", "role_confidence": 0.9, "evidence": ["panel label / figure inner text: (H)"], "seed_role": "figure_inner_text", "seed_confidence": 0.9, "seed_evidence": ["panel label / figure inner text: (H)"], "span_metadata": null, "raw_observation": {"block_id": 17, "page": 9, "raw_label": "figure_title", "text": "(H)", "bbox": [479, 762, 511, 785], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "panel_label", "raw_marker": "(H)", "number": null, "kind": "panel_label", "normalized_text": "(H)"}, "layout_signature": {"width": 32, "width_bucket": 25, "height": 23, "left": 479, "top": 762, "right": 511, "bottom": 785, "x_center": 495.0, "x_center_bucket": 500, "y_center": 773.5, "x_ratio": 0.4156, "y_ratio": 0.4942, "width_ratio": 0.0269, "height_ratio": 0.0147, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "display_zone", "style_family": "legend_like", "style_family_authority": "figure_marker", "reading_band_id": "band_136", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 9, "block_id": 18, "raw_label": "figure_title", "raw_order": null, "bbox": [117, 855, 147, 879], "text": "(E)", "page_width": 1191, "page_height": 1565, "role": "figure_inner_text", "role_confidence": 0.9, "evidence": ["panel label / figure inner text: (E)"], "seed_role": "figure_inner_text", "seed_confidence": 0.9, "seed_evidence": ["panel label / figure inner text: (E)"], "span_metadata": null, "raw_observation": {"block_id": 18, "page": 9, "raw_label": "figure_title", "text": "(E)", "bbox": [117, 855, 147, 879], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "panel_label", "raw_marker": "(E)", "number": null, "kind": "panel_label", "normalized_text": "(E)"}, "layout_signature": {"width": 30, "width_bucket": 25, "height": 24, "left": 117, "top": 855, "right": 147, "bottom": 879, "x_center": 132.0, "x_center_bucket": 125, "y_center": 867.0, "x_ratio": 0.1108, "y_ratio": 0.554, "width_ratio": 0.0252, "height_ratio": 0.0153, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "display_zone", "style_family": "legend_like", "style_family_authority": "figure_marker", "reading_band_id": "band_136", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 9, "block_id": 19, "raw_label": "image", "raw_order": null, "bbox": [479, 763, 820, 877], "text": "", "page_width": 1191, "page_height": 1565, "role": "figure_asset", "role_confidence": 0.85, "evidence": ["media label: image"], "seed_role": "media_asset", "seed_confidence": 0.85, "seed_evidence": ["media label: image"], "span_metadata": null, "raw_observation": {"block_id": 19, "page": 9, "raw_label": "image", "text": "", "bbox": [479, 763, 820, 877], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "empty", "raw_marker": null, "number": null, "kind": null, "normalized_text": ""}, "layout_signature": {"width": 341, "width_bucket": 350, "height": 114, "left": 479, "top": 763, "right": 820, "bottom": 877, "x_center": 649.5, "x_center_bucket": 650, "y_center": 820.0, "x_ratio": 0.5453, "y_ratio": 0.524, "width_ratio": 0.2863, "height_ratio": 0.0728, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_136", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"], "asset_family_hint": "figure_like", "asset_family_confidence": 0.7, "asset_family_evidence": ["raw_label:image"]}
+{"paper_id": "2HEUD5P9", "page": 9, "block_id": 20, "raw_label": "figure_title", "raw_order": null, "bbox": [839, 772, 873, 795], "text": "(K)", "page_width": 1191, "page_height": 1565, "role": "figure_inner_text", "role_confidence": 0.9, "evidence": ["panel label / figure inner text: (K)"], "seed_role": "figure_inner_text", "seed_confidence": 0.9, "seed_evidence": ["panel label / figure inner text: (K)"], "span_metadata": null, "raw_observation": {"block_id": 20, "page": 9, "raw_label": "figure_title", "text": "(K)", "bbox": [839, 772, 873, 795], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "panel_label", "raw_marker": "(K)", "number": null, "kind": "panel_label", "normalized_text": "(K)"}, "layout_signature": {"width": 34, "width_bucket": 25, "height": 23, "left": 839, "top": 772, "right": 873, "bottom": 795, "x_center": 856.0, "x_center_bucket": 850, "y_center": 783.5, "x_ratio": 0.7187, "y_ratio": 0.5006, "width_ratio": 0.0285, "height_ratio": 0.0147, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "display_zone", "style_family": "legend_like", "style_family_authority": "figure_marker", "reading_band_id": "band_136", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 9, "block_id": 21, "raw_label": "image", "raw_order": null, "bbox": [126, 859, 467, 1016], "text": "", "page_width": 1191, "page_height": 1565, "role": "figure_asset", "role_confidence": 0.85, "evidence": ["media label: image"], "seed_role": "media_asset", "seed_confidence": 0.85, "seed_evidence": ["media label: image"], "span_metadata": null, "raw_observation": {"block_id": 21, "page": 9, "raw_label": "image", "text": "", "bbox": [126, 859, 467, 1016], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "empty", "raw_marker": null, "number": null, "kind": null, "normalized_text": ""}, "layout_signature": {"width": 341, "width_bucket": 350, "height": 157, "left": 126, "top": 859, "right": 467, "bottom": 1016, "x_center": 296.5, "x_center_bucket": 300, "y_center": 937.5, "x_ratio": 0.249, "y_ratio": 0.599, "width_ratio": 0.2863, "height_ratio": 0.1003, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_133", "display_cluster_candidate_id": "disp_26_0", "layout_region": "display_zone", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"], "asset_family_hint": "figure_like", "asset_family_confidence": 0.7, "asset_family_evidence": ["raw_label:image"]}
+{"paper_id": "2HEUD5P9", "page": 9, "block_id": 22, "raw_label": "image", "raw_order": null, "bbox": [836, 773, 1089, 861], "text": "", "page_width": 1191, "page_height": 1565, "role": "figure_asset", "role_confidence": 0.85, "evidence": ["media label: image"], "seed_role": "media_asset", "seed_confidence": 0.85, "seed_evidence": ["media label: image"], "span_metadata": null, "raw_observation": {"block_id": 22, "page": 9, "raw_label": "image", "text": "", "bbox": [836, 773, 1089, 861], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "empty", "raw_marker": null, "number": null, "kind": null, "normalized_text": ""}, "layout_signature": {"width": 253, "width_bucket": 250, "height": 88, "left": 836, "top": 773, "right": 1089, "bottom": 861, "x_center": 962.5, "x_center_bucket": 950, "y_center": 817.0, "x_ratio": 0.8081, "y_ratio": 0.522, "width_ratio": 0.2124, "height_ratio": 0.0562, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_134", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"], "asset_family_hint": "figure_like", "asset_family_confidence": 0.7, "asset_family_evidence": ["raw_label:image"]}
+{"paper_id": "2HEUD5P9", "page": 9, "block_id": 23, "raw_label": "chart", "raw_order": null, "bbox": [484, 884, 635, 1017], "text": "", "page_width": 1191, "page_height": 1565, "role": "figure_asset", "role_confidence": 0.85, "evidence": ["media label: chart"], "seed_role": "media_asset", "seed_confidence": 0.85, "seed_evidence": ["media label: chart"], "span_metadata": null, "raw_observation": {"block_id": 23, "page": 9, "raw_label": "chart", "text": "", "bbox": [484, 884, 635, 1017], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "empty", "raw_marker": null, "number": null, "kind": null, "normalized_text": ""}, "layout_signature": {"width": 151, "width_bucket": 150, "height": 133, "left": 484, "top": 884, "right": 635, "bottom": 1017, "x_center": 559.5, "x_center_bucket": 550, "y_center": 950.5, "x_ratio": 0.4698, "y_ratio": 0.6073, "width_ratio": 0.1268, "height_ratio": 0.085, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_133", "display_cluster_candidate_id": "disp_26_0", "layout_region": "display_zone", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"], "asset_family_hint": "figure_like", "asset_family_confidence": 0.7, "asset_family_evidence": ["raw_label:chart"]}
+{"paper_id": "2HEUD5P9", "page": 9, "block_id": 24, "raw_label": "chart", "raw_order": null, "bbox": [633, 885, 824, 1017], "text": "", "page_width": 1191, "page_height": 1565, "role": "figure_asset", "role_confidence": 0.85, "evidence": ["media label: chart"], "seed_role": "media_asset", "seed_confidence": 0.85, "seed_evidence": ["media label: chart"], "span_metadata": null, "raw_observation": {"block_id": 24, "page": 9, "raw_label": "chart", "text": "", "bbox": [633, 885, 824, 1017], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "empty", "raw_marker": null, "number": null, "kind": null, "normalized_text": ""}, "layout_signature": {"width": 191, "width_bucket": 200, "height": 132, "left": 633, "top": 885, "right": 824, "bottom": 1017, "x_center": 728.5, "x_center_bucket": 725, "y_center": 951.0, "x_ratio": 0.6117, "y_ratio": 0.6077, "width_ratio": 0.1604, "height_ratio": 0.0843, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_134", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"], "asset_family_hint": "figure_like", "asset_family_confidence": 0.7, "asset_family_evidence": ["raw_label:chart"]}
+{"paper_id": "2HEUD5P9", "page": 9, "block_id": 25, "raw_label": "image", "raw_order": null, "bbox": [822, 866, 1090, 1016], "text": "", "page_width": 1191, "page_height": 1565, "role": "figure_asset", "role_confidence": 0.85, "evidence": ["media label: image"], "seed_role": "media_asset", "seed_confidence": 0.85, "seed_evidence": ["media label: image"], "span_metadata": null, "raw_observation": {"block_id": 25, "page": 9, "raw_label": "image", "text": "", "bbox": [822, 866, 1090, 1016], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "empty", "raw_marker": null, "number": null, "kind": null, "normalized_text": ""}, "layout_signature": {"width": 268, "width_bucket": 275, "height": 150, "left": 822, "top": 866, "right": 1090, "bottom": 1016, "x_center": 956.0, "x_center_bucket": 950, "y_center": 941.0, "x_ratio": 0.8027, "y_ratio": 0.6013, "width_ratio": 0.225, "height_ratio": 0.0958, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_131", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"], "asset_family_hint": "figure_like", "asset_family_confidence": 0.7, "asset_family_evidence": ["raw_label:image"]}
+{"paper_id": "2HEUD5P9", "page": 9, "block_id": 26, "raw_label": "figure_title", "raw_order": null, "bbox": [94, 1025, 1101, 1160], "text": "Figure 3. A) Biomimetic melt electrowritten lattice and bioglass particle reinforced hydrogel scaffolds were fabricated. B) The weight percents of Ca, P, and Ca/P ratio for all the scaffolds. C) FTIR curves of formed HAp on scaffolds. $ ^{[87]} $ Copyright 2022, Elsevier. D) Representative SEM images, photographs (insert), and diameter distribution analysis of P-scaffold and iTE-scaffold. E) Micro-CT reconstructed 3D images of the rat mandibular bone defects. Green color displayed the newly formed bone in the defect sites. $ ^{[90]} $ Copyright 2021, Springer Nature. F) The ALP staining results of BMSCs cultured on EFMs with different CS ratios at 4th and 7th days. G) Semi-quantitative results of ALP expression in BMSCs cocultured with EFMs on the 4th and 7th day. H) Micro-CT image of blank, PCL and PCL0.625 groups in skull defect areas. I) BV/TV results of blank, PCL and PCL0.625 groups. J) Semi-quantitative data of fluorescent bands labeled by TE, AL, and CA. K) VG staining of blank, PCL and PCL0.625 groups in skull defects area. $ ^{[97]} $ Copyright 2023, Elsevier.", "page_width": 1191, "page_height": 1565, "role": "figure_caption", "role_confidence": 0.92, "evidence": ["figure_title label: Figure 3. A) Biomimetic melt electrowritten lattice and biog"], "seed_role": "figure_caption", "seed_confidence": 0.92, "seed_evidence": ["figure_title label: Figure 3. A) Biomimetic melt electrowritten lattice and biog"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaSansPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaSansPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaSansPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaSansPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaSansPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaSansPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaSansPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaSansPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaSansPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 26, "page": 9, "raw_label": "figure_title", "text": "Figure 3. A) Biomimetic melt electrowritten lattice and bioglass particle reinforced hydrogel scaffolds were fabricated. B) The weight percents of Ca, P, and Ca/P ratio for all the scaffolds. C) FTIR curves of formed HAp on scaffolds. $ ^{[87]} $ Copyright 2022, Elsevier. D) Representative SEM images, photographs (insert), and diameter distribution analysis of P-scaffold and iTE-scaffold. E) Micro-CT reconstructed 3D images of the rat mandibular bone defects. Green color displayed the newly formed bone in the defect sites. $ ^{[90]} $ Copyright 2021, Springer Nature. F) The ALP staining results of BMSCs cultured on EFMs with different CS ratios at 4th and 7th days. G) Semi-quantitative results of ALP expression in BMSCs cocultured with EFMs on the 4th and 7th day. H) Micro-CT image of blank, PCL and PCL0.625 groups in skull defect areas. I) BV/TV results of blank, PCL and PCL0.625 groups. J) Semi-quantitative data of fluorescent bands labeled by TE, AL, and CA. K) VG staining of blank, PCL and PCL0.625 groups in skull defects area. $ ^{[97]} $ Copyright 2023, Elsevier.", "bbox": [94, 1025, 1101, 1160], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "figure_number", "raw_marker": "Figure 3", "number": 3, "kind": "figure", "normalized_text": "Figure 3. A) Biomimetic melt electrowritten lattice and bioglass particle reinforced hydrogel scaffolds were fabricated. B) The weight percents of Ca, P, and Ca/P ratio for all the scaffolds. C) FTIR curves of formed HAp on scaffolds. $ ^{[87]} $ Copyright 2022, Elsevier. D) Representative SEM images, photographs (insert), and diameter distribution analysis of P-scaffold and iTE-scaffold. E) Micro-CT reconstructed 3D images of the rat mandibular bone defects. Green color displayed the newly formed bone in the defect sites. $ ^{[90]} $ Copyright 2021, Springer Nature. F) The ALP staining results of BMSCs cultured on EFMs with different CS ratios at 4th and 7th days. G) Semi-quantitative results of ALP expression in BMSCs cocultured with EFMs on the 4th and 7th day. H) Micro-CT image of blank, PCL and PCL0.625 groups in skull defect areas. I) BV/TV results of blank, PCL and PCL0.625 groups. J) Semi-quantitative data of fluorescent bands labeled by TE, AL, and CA. K) VG staining of blank, PCL and PCL0.625 groups in skull defects area. $ ^{[97]} $ Copyright 2023, Elsevier."}, "layout_signature": {"width": 1007, "width_bucket": 1000, "height": 135, "left": 94, "top": 1025, "right": 1101, "bottom": 1160, "x_center": 597.5, "x_center_bucket": 600, "y_center": 1092.5, "x_ratio": 0.5017, "y_ratio": 0.6981, "width_ratio": 0.8455, "height_ratio": 0.0863, "line_count": 1}, "span_signature": {"font_size": 7.22, "font_size_median": 7.97, "font_size_bucket": 7.0, "font_family_norm": "ScalaSansPro-Bold", "bold": true, "italic": true, "span_count": 24}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "display_zone", "style_family": "legend_like", "style_family_authority": "figure_marker", "reading_band_id": "band_135", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "hard", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.0, "decision": "body", "evidence": []}, "role_verification_status": "ACCEPT", "role_source": "accepted_figure_caption_artifact", "role_evidence": ["figure caption matched accepted figure artifact"]}
+{"paper_id": "2HEUD5P9", "page": 9, "block_id": 27, "raw_label": "text", "raw_order": 1, "bbox": [95, 1200, 588, 1443], "text": "degradation rate and poor hydrophilicity restrict its application in bone tissue engineering. To overcome these shortcomings, PCL can be compounded with other materials, doped and modified. Among them, compounding PCL with inorganic materials such as hydroxyapatite (HAP) can improve the mechanical properties and bioactivity of PCL. In addition, compounding PCL with biodegradable polymers such as polylactic acid (PLA) can improve the degradation rate and bioactivity of PCL. In summary, PCL has broad potential applications in bone repair and regeneration, but further research and improvement are needed.\nDifferent kinds of polymeric scaffolds have increasingly been employed in bone repair and regeneration for the past few years. Polymeric scaffolds combined with growth factors and stem cells can modulate the physicochemical properties of biological tissue. The advantages and disadvantages of natural polymers and synthetic polymers were listed as follows (Table 2). Polymeric scaffolds combined with some materials that possess appropriate properties, such as mechanical, biocompatible, and biodegradable properties, as well as structural similarity to the ECM of natural bone may offer a suitable environment for cell proliferation, adhesion, differentiation, and new bone formation. The", "page_width": 1191, "page_height": 1565, "role": "body_paragraph", "role_confidence": 0.6, "evidence": ["default body_paragraph for text label"], "seed_role": "body_paragraph", "seed_confidence": 0.6, "seed_evidence": ["default body_paragraph for text label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 27, "page": 9, "raw_label": "text", "text": "degradation rate and poor hydrophilicity restrict its application in bone tissue engineering. To overcome these shortcomings, PCL can be compounded with other materials, doped and modified. Among them, compounding PCL with inorganic materials such as hydroxyapatite (HAP) can improve the mechanical properties and bioactivity of PCL. In addition, compounding PCL with biodegradable polymers such as polylactic acid (PLA) can improve the degradation rate and bioactivity of PCL. In summary, PCL has broad potential applications in bone repair and regeneration, but further research and improvement are needed.\nDifferent kinds of polymeric scaffolds have increasingly been employed in bone repair and regeneration for the past few years. Polymeric scaffolds combined with growth factors and stem cells can modulate the physicochemical properties of biological tissue. The advantages and disadvantages of natural polymers and synthetic polymers were listed as follows (Table 2). Polymeric scaffolds combined with some materials that possess appropriate properties, such as mechanical, biocompatible, and biodegradable properties, as well as structural similarity to the ECM of natural bone may offer a suitable environment for cell proliferation, adhesion, differentiation, and new bone formation. The", "bbox": [95, 1200, 588, 1443], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "degradation rate and poor hydrophilicity restrict its application in bone tissue engineering. To overcome these shortcomings, PCL can be compounded with other materials, doped and modified. Among them, compounding PCL with inorganic materials such as hydroxyapatite (HAP) can improve the mechanical properties and bioactivity of PCL. In addition, compounding PCL with biodegradable polymers such as polylactic acid (PLA) can improve the degradation rate and bioactivity of PCL. In summary, PCL has broad potential applications in bone repair and regeneration, but further research and improvement are needed.\nDifferent kinds of polymeric scaffolds have increasingly been employed in bone repair and regeneration for the past few years. Polymeric scaffolds combined with growth factors and stem cells can modulate the physicochemical properties of biological tissue. The advantages and disadvantages of natural polymers and synthetic polymers were listed as follows (Table 2). Polymeric scaffolds combined with some materials that possess appropriate properties, such as mechanical, biocompatible, and biodegradable properties, as well as structural similarity to the ECM of natural bone may offer a suitable environment for cell proliferation, adhesion, differentiation, and new bone formation. The"}, "layout_signature": {"width": 493, "width_bucket": 500, "height": 243, "left": 95, "top": 1200, "right": 588, "bottom": 1443, "x_center": 341.5, "x_center_bucket": 350, "y_center": 1321.5, "x_ratio": 0.2867, "y_ratio": 0.8444, "width_ratio": 0.4139, "height_ratio": 0.1553, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaPro-Regular", "bold": false, "italic": true, "span_count": 137}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_137", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 9, "block_id": 28, "raw_label": "text", "raw_order": 2, "bbox": [604, 1199, 1099, 1444], "text": "", "page_width": 1191, "page_height": 1565, "role": "ocr_text_missing", "role_confidence": 0.8, "evidence": ["ocr detected text region (raw_label=text) but no text extracted; no pdf backfill available"], "seed_role": "ocr_text_missing", "seed_confidence": 0.8, "seed_evidence": ["ocr detected text region (raw_label=text) but no text extracted; no pdf backfill available"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Bold", "flags": 20, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Bold", "flags": 20, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Bold", "flags": 20, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 28, "page": 9, "raw_label": "text", "text": "", "bbox": [604, 1199, 1099, 1444], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "empty", "raw_marker": null, "number": null, "kind": null, "normalized_text": ""}, "layout_signature": {"width": 495, "width_bucket": 500, "height": 245, "left": 604, "top": 1199, "right": 1099, "bottom": 1444, "x_center": 851.5, "x_center_bucket": 850, "y_center": 1321.5, "x_ratio": 0.7149, "y_ratio": 0.8444, "width_ratio": 0.4156, "height_ratio": 0.1565, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaPro-Regular", "bold": true, "italic": true, "span_count": 109}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": "pdf_text_layer_fallback_rejected", "_ocr_raw_status": "missing_text_rejected", "_ocr_raw_error_type": "backfill_overlaps_existing_text_block", "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "_needs_pdf_fallback": true, "reading_band_id": "band_137", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 9, "block_id": 29, "raw_label": "footer", "raw_order": null, "bbox": [99, 1487, 289, 1505], "text": "Small Methods 2024, 8, 2301283", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["footer label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["footer label"], "span_metadata": [{"size": 6.973800182342529, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 29, "page": 9, "raw_label": "footer", "text": "Small Methods 2024, 8, 2301283", "bbox": [99, 1487, 289, 1505], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "Small Methods 2024, 8, 2301283"}, "layout_signature": {"width": 190, "width_bucket": 200, "height": 18, "left": 99, "top": 1487, "right": 289, "bottom": 1505, "x_center": 194.0, "x_center_bucket": 200, "y_center": 1496.0, "x_ratio": 0.1629, "y_ratio": 0.9559, "width_ratio": 0.1595, "height_ratio": 0.0115, "line_count": 1}, "span_signature": {"font_size": 6.97, "font_size_median": 6.97, "font_size_bucket": 7.0, "font_family_norm": "ScalaSansPro-Italic", "bold": true, "italic": true, "span_count": 5}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_126", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 9, "block_id": 30, "raw_label": "number", "raw_order": null, "bbox": [530, 1484, 664, 1508], "text": "2301283 (9 of 27)", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["page number label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["page number label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaSansPro-Bold", "flags": 20, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 30, "page": 9, "raw_label": "number", "text": "2301283 (9 of 27)", "bbox": [530, 1484, 664, 1508], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_dot", "raw_marker": "2301283", "number": 2301283, "kind": "reference", "normalized_text": "2301283 (9 of 27)"}, "layout_signature": {"width": 134, "width_bucket": 125, "height": 24, "left": 530, "top": 1484, "right": 664, "bottom": 1508, "x_center": 597.0, "x_center_bucket": 600, "y_center": 1496.0, "x_ratio": 0.5013, "y_ratio": 0.9559, "width_ratio": 0.1125, "height_ratio": 0.0153, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaSansPro-Bold", "bold": true, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_126", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 9, "block_id": 31, "raw_label": "footer", "raw_order": null, "bbox": [937, 1486, 1096, 1506], "text": "© 2024 Wiley-VCH GmbH", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["footer label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["footer label"], "span_metadata": [{"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 31, "page": 9, "raw_label": "footer", "text": "© 2024 Wiley-VCH GmbH", "bbox": [937, 1486, 1096, 1506], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "© 2024 Wiley-VCH GmbH"}, "layout_signature": {"width": 159, "width_bucket": 150, "height": 20, "left": 937, "top": 1486, "right": 1096, "bottom": 1506, "x_center": 1016.5, "x_center_bucket": 1025, "y_center": 1496.0, "x_ratio": 0.8535, "y_ratio": 0.9559, "width_ratio": 0.1335, "height_ratio": 0.0128, "line_count": 1}, "span_signature": {"font_size": 6.97, "font_size_median": 6.97, "font_size_bucket": 7.0, "font_family_norm": "ScalaSansPro-Regular", "bold": false, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_126", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 9, "block_id": 32, "raw_label": "aside_text", "raw_order": null, "bbox": [1155, 32, 1171, 1536], "text": "23699608, 2024, 8, Downloaded from https://onlinelibrary.wiley.com/doi/10.1002/smll.202301283 by Shandong University Library, Wiley Online Library on [18/02/2026]. See the Terms and Conditions (https://onlinelibrary.wiley.com/terms-and-conditions) on Wiley Online Library for rules of use; OA articles are governed by the applicable Creative Commons License.", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.95, "evidence": ["margin-band narrow/tall geometry; treated as noise"], "seed_role": "noise", "seed_confidence": 0.95, "seed_evidence": ["margin-band narrow/tall geometry; treated as noise"], "span_metadata": [{"size": 5.03000020980835, "font": "Times-Roman", "flags": 4, "color": 0, "dir": [0.0, 1.0], "wmode": 0}], "raw_observation": {"block_id": 32, "page": 9, "raw_label": "aside_text", "text": "23699608, 2024, 8, Downloaded from https://onlinelibrary.wiley.com/doi/10.1002/smll.202301283 by Shandong University Library, Wiley Online Library on [18/02/2026]. See the Terms and Conditions (https://onlinelibrary.wiley.com/terms-and-conditions) on Wiley Online Library for rules of use; OA articles are governed by the applicable Creative Commons License.", "bbox": [1155, 32, 1171, 1536], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "23699608, 2024, 8, Downloaded from https://onlinelibrary.wiley.com/doi/10.1002/smll.202301283 by Shandong University Library, Wiley Online Library on [18/02/2026]. See the Terms and Conditions (https://onlinelibrary.wiley.com/terms-and-conditions) on Wiley Online Library for rules of use; OA articles are governed by the applicable Creative Commons License."}, "layout_signature": {"width": 16, "width_bucket": 25, "height": 1504, "left": 1155, "top": 32, "right": 1171, "bottom": 1536, "x_center": 1163.0, "x_center_bucket": 1175, "y_center": 784.0, "x_ratio": 0.9765, "y_ratio": 0.501, "width_ratio": 0.0134, "height_ratio": 0.961, "line_count": 1}, "span_signature": {"font_size": 5.03, "font_size_median": 5.03, "font_size_bucket": 5.0, "font_family_norm": "Times-Roman", "bold": false, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_126", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 10, "block_id": 0, "raw_label": "header", "raw_order": null, "bbox": [91, 45, 338, 116], "text": "ADVANCED\nSCIENCE NEWS\nwww.advancedsciencenews.com", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["header label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["header label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaSansPro-Bold", "flags": 20, "color": 255, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 0, "page": 10, "raw_label": "header", "text": "ADVANCED\nSCIENCE NEWS\nwww.advancedsciencenews.com", "bbox": [91, 45, 338, 116], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "ADVANCED\nSCIENCE NEWS\nwww.advancedsciencenews.com"}, "layout_signature": {"width": 247, "width_bucket": 250, "height": 71, "left": 91, "top": 45, "right": 338, "bottom": 116, "x_center": 214.5, "x_center_bucket": 225, "y_center": 80.5, "x_ratio": 0.1801, "y_ratio": 0.0514, "width_ratio": 0.2074, "height_ratio": 0.0454, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaSansPro-Bold", "bold": true, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 10, "block_id": 1, "raw_label": "header_image", "raw_order": null, "bbox": [896, 36, 1092, 116], "text": "", "page_width": 1191, "page_height": 1565, "role": "unknown_structural", "role_confidence": 0.2, "evidence": ["unrecognized label 'header_image'"], "seed_role": "unknown_structural", "seed_confidence": 0.2, "seed_evidence": ["unrecognized label 'header_image'"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaSansPro-Bold", "flags": 20, "color": 255, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 1, "page": 10, "raw_label": "header_image", "text": "", "bbox": [896, 36, 1092, 116], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "empty", "raw_marker": null, "number": null, "kind": null, "normalized_text": ""}, "layout_signature": {"width": 196, "width_bucket": 200, "height": 80, "left": 896, "top": 36, "right": 1092, "bottom": 116, "x_center": 994.0, "x_center_bucket": 1000, "y_center": 76.0, "x_ratio": 0.8346, "y_ratio": 0.0486, "width_ratio": 0.1646, "height_ratio": 0.0511, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaSansPro-Bold", "bold": true, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": true, "zone": "body_zone", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_142", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["non-structural role accepted"]}
+{"paper_id": "2HEUD5P9", "page": 10, "block_id": 2, "raw_label": "figure_title", "raw_order": null, "bbox": [91, 149, 551, 171], "text": "Table 2. Summarization of polymers: advantages and disadvantages.", "page_width": 1191, "page_height": 1565, "role": "table_caption", "role_confidence": 0.9, "evidence": ["table prefix matched: Table 2. Summarization of polymers: advantages and disadvant"], "seed_role": "table_caption", "seed_confidence": 0.9, "seed_evidence": ["table prefix matched: Table 2. Summarization of polymers: advantages and disadvant"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 2, "page": 10, "raw_label": "figure_title", "text": "Table 2. Summarization of polymers: advantages and disadvantages.", "bbox": [91, 149, 551, 171], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "table_number", "raw_marker": "Table 2", "number": 2, "kind": "table", "normalized_text": "Table 2. Summarization of polymers: advantages and disadvantages."}, "layout_signature": {"width": 460, "width_bucket": 450, "height": 22, "left": 91, "top": 149, "right": 551, "bottom": 171, "x_center": 321.0, "x_center_bucket": 325, "y_center": 160.0, "x_ratio": 0.2695, "y_ratio": 0.1022, "width_ratio": 0.3862, "height_ratio": 0.0141, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Bold", "bold": true, "italic": true, "span_count": 2}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "display_zone", "style_family": "table_caption_like", "style_family_authority": "table_marker", "reading_band_id": "band_142", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "text_evidence_table_caption", "role_evidence": ["table caption accepted via text-prefix + marker/zone evidence"]}
+{"paper_id": "2HEUD5P9", "page": 10, "block_id": 3, "raw_label": "table", "raw_order": null, "bbox": [91, 182, 1085, 1037], "text": "| Type of polymers | Examples | Advantages | Disadvantages | References |
| Natural polymers | Chitosan | Resistance to bacteria Easy properties tunability Cell-binding, differentiation and migration properties Controlled biodegradability | Poor mechanical strength Low solubility | [54,55] |
| Alginate | Easy gelling Tunable properties High abundance resources | Low cell adhesion Difficult to sterilize | [60,61] |
| Hyaluronic acid | Biodegradability Easy manipulation Water solubility Osteoinduction | Poor mechanical properties Rapid degradation | [65,66] |
| Collagen | Similar to ECM Possible injectability Cell-binding properties Versatility in being processed in different physical forms High porosity Facility for combining with other polymers | Difficult disinfection Difficult handling Low mechanical strength | [70,71] |
| Gelatin | Porosity tunability Biodegradability Osteoconductivity | Poor mechanical properties Low stability in physiological conditions | [73,74] |
| Silk fibroin | Immunogenicity Controlled biodegradability High mechanical strength Easy chemical modification | Low osteogenic capacity | [79,80] |
| Synthetic polymers | PLA | Tunable properties Thermal stability Sufficient mechanical properties | Poor osteoinduction Poor cell adhesion | [82,83] |
| PGA | Cytocompatibility Composited with other biomaterials | Poor mechanical strength Low cell adhesion Rapid biodegradability Poor osteoinduction | [88,89] |
| PLGA | Tunable degradation rate Biocompatibility Biodegradability Controllable mechanical properties | Poor osteoconductivity Poor cell adhesion Suboptimal mechanical properties | [91,92] |
| PCL | Biodegradability Slow degradation rate Excellent mechanical properties | Low biodegradability Poor hydrophilicity Low bioactivity | [94,95] |
", "page_width": 1191, "page_height": 1565, "role": "table_html", "role_confidence": 0.85, "evidence": ["media label: table"], "seed_role": "media_asset", "seed_confidence": 0.85, "seed_evidence": ["media label: table"], "span_metadata": [{"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 3, "page": 10, "raw_label": "table", "text": "| Type of polymers | Examples | Advantages | Disadvantages | References |
| Natural polymers | Chitosan | Resistance to bacteria Easy properties tunability Cell-binding, differentiation and migration properties Controlled biodegradability | Poor mechanical strength Low solubility | [54,55] |
| Alginate | Easy gelling Tunable properties High abundance resources | Low cell adhesion Difficult to sterilize | [60,61] |
| Hyaluronic acid | Biodegradability Easy manipulation Water solubility Osteoinduction | Poor mechanical properties Rapid degradation | [65,66] |
| Collagen | Similar to ECM Possible injectability Cell-binding properties Versatility in being processed in different physical forms High porosity Facility for combining with other polymers | Difficult disinfection Difficult handling Low mechanical strength | [70,71] |
| Gelatin | Porosity tunability Biodegradability Osteoconductivity | Poor mechanical properties Low stability in physiological conditions | [73,74] |
| Silk fibroin | Immunogenicity Controlled biodegradability High mechanical strength Easy chemical modification | Low osteogenic capacity | [79,80] |
| Synthetic polymers | PLA | Tunable properties Thermal stability Sufficient mechanical properties | Poor osteoinduction Poor cell adhesion | [82,83] |
| PGA | Cytocompatibility Composited with other biomaterials | Poor mechanical strength Low cell adhesion Rapid biodegradability Poor osteoinduction | [88,89] |
| PLGA | Tunable degradation rate Biocompatibility Biodegradability Controllable mechanical properties | Poor osteoconductivity Poor cell adhesion Suboptimal mechanical properties | [91,92] |
| PCL | Biodegradability Slow degradation rate Excellent mechanical properties | Low biodegradability Poor hydrophilicity Low bioactivity | [94,95] |
", "bbox": [91, 182, 1085, 1037], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "| Type of polymers | Examples | Advantages | Disadvantages | References |
| Natural polymers | Chitosan | Resistance to bacteria Easy properties tunability Cell-binding, differentiation and migration properties Controlled biodegradability | Poor mechanical strength Low solubility | [54,55] |
| Alginate | Easy gelling Tunable properties High abundance resources | Low cell adhesion Difficult to sterilize | [60,61] |
| Hyaluronic acid | Biodegradability Easy manipulation Water solubility Osteoinduction | Poor mechanical properties Rapid degradation | [65,66] |
| Collagen | Similar to ECM Possible injectability Cell-binding properties Versatility in being processed in different physical forms High porosity Facility for combining with other polymers | Difficult disinfection Difficult handling Low mechanical strength | [70,71] |
| Gelatin | Porosity tunability Biodegradability Osteoconductivity | Poor mechanical properties Low stability in physiological conditions | [73,74] |
| Silk fibroin | Immunogenicity Controlled biodegradability High mechanical strength Easy chemical modification | Low osteogenic capacity | [79,80] |
| Synthetic polymers | PLA | Tunable properties Thermal stability Sufficient mechanical properties | Poor osteoinduction Poor cell adhesion | [82,83] |
| PGA | Cytocompatibility Composited with other biomaterials | Poor mechanical strength Low cell adhesion Rapid biodegradability Poor osteoinduction | [88,89] |
| PLGA | Tunable degradation rate Biocompatibility Biodegradability Controllable mechanical properties | Poor osteoconductivity Poor cell adhesion Suboptimal mechanical properties | [91,92] |
| PCL | Biodegradability Slow degradation rate Excellent mechanical properties | Low biodegradability Poor hydrophilicity Low bioactivity | [94,95] |
"}, "layout_signature": {"width": 994, "width_bucket": 1000, "height": 855, "left": 91, "top": 182, "right": 1085, "bottom": 1037, "x_center": 588.0, "x_center_bucket": 600, "y_center": 609.5, "x_ratio": 0.4937, "y_ratio": 0.3895, "width_ratio": 0.8346, "height_ratio": 0.5463, "line_count": 1}, "span_signature": {"font_size": 6.97, "font_size_median": 6.97, "font_size_bucket": 7.0, "font_family_norm": "ScalaSansPro-Regular", "bold": false, "italic": true, "span_count": 109}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_139", "display_cluster_candidate_id": "disp_27_0", "layout_region": "display_zone", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.0, "decision": "body", "evidence": []}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"], "asset_family_hint": "table_like", "asset_family_confidence": 0.7, "asset_family_evidence": ["raw_label:table"]}
+{"paper_id": "2HEUD5P9", "page": 10, "block_id": 4, "raw_label": "text", "raw_order": 1, "bbox": [90, 1091, 582, 1270], "text": "current limitations of polymeric scaffolds in bone repair and regeneration include the possible retention of toxic products resulting from polymer degradation, denaturation of biomolecules bound to the polymeric scaffolds, difficulty in controlling pore sizes, and suboptimal mechanical properties. Before bioactive polymeric scaffolds can be translated into clinical practice, it is imperative that the long-term biological effects of polymeric scaffolds require comprehensive investigation.", "page_width": 1191, "page_height": 1565, "role": "body_paragraph", "role_confidence": 0.6, "evidence": ["default body_paragraph for text label"], "seed_role": "body_paragraph", "seed_confidence": 0.6, "seed_evidence": ["default body_paragraph for text label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 4, "page": 10, "raw_label": "text", "text": "current limitations of polymeric scaffolds in bone repair and regeneration include the possible retention of toxic products resulting from polymer degradation, denaturation of biomolecules bound to the polymeric scaffolds, difficulty in controlling pore sizes, and suboptimal mechanical properties. Before bioactive polymeric scaffolds can be translated into clinical practice, it is imperative that the long-term biological effects of polymeric scaffolds require comprehensive investigation.", "bbox": [90, 1091, 582, 1270], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "current limitations of polymeric scaffolds in bone repair and regeneration include the possible retention of toxic products resulting from polymer degradation, denaturation of biomolecules bound to the polymeric scaffolds, difficulty in controlling pore sizes, and suboptimal mechanical properties. Before bioactive polymeric scaffolds can be translated into clinical practice, it is imperative that the long-term biological effects of polymeric scaffolds require comprehensive investigation."}, "layout_signature": {"width": 492, "width_bucket": 500, "height": 179, "left": 90, "top": 1091, "right": 582, "bottom": 1270, "x_center": 336.0, "x_center_bucket": 325, "y_center": 1180.5, "x_ratio": 0.2821, "y_ratio": 0.7543, "width_ratio": 0.4131, "height_ratio": 0.1144, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaPro-Regular", "bold": false, "italic": true, "span_count": 70}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_140", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 10, "block_id": 5, "raw_label": "paragraph_title", "raw_order": 2, "bbox": [91, 1307, 182, 1328], "text": "2.3. Metals", "page_width": 1191, "page_height": 1565, "role": "subsection_heading", "role_confidence": 0.85, "evidence": ["paragraph_title label with numbering: 2.3. Metals"], "seed_role": "subsection_heading", "seed_confidence": 0.85, "seed_evidence": ["paragraph_title label with numbering: 2.3. Metals"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaSansPro-Bold", "flags": 20, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 5, "page": 10, "raw_label": "paragraph_title", "text": "2.3. Metals", "bbox": [91, 1307, 182, 1328], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "heading_numbered", "raw_marker": "2.3", "number": "2.3", "kind": "heading", "normalized_text": "2.3. Metals"}, "layout_signature": {"width": 91, "width_bucket": 100, "height": 21, "left": 91, "top": 1307, "right": 182, "bottom": 1328, "x_center": 136.5, "x_center_bucket": 125, "y_center": 1317.5, "x_ratio": 0.1146, "y_ratio": 0.8419, "width_ratio": 0.0764, "height_ratio": 0.0134, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaSansPro-Bold", "bold": true, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_139", "display_cluster_candidate_id": "disp_27_0", "layout_region": "display_zone", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "accepted_heading", "role_evidence": ["heading verified by heading artifact"]}
+{"paper_id": "2HEUD5P9", "page": 10, "block_id": 6, "raw_label": "text", "raw_order": 3, "bbox": [90, 1350, 582, 1440], "text": "Metals with excellent mechanical properties and load-bearing capacities are ideal for bone implantation and cardiovascular stents. Commonly used metallic materials, such as titanium, magnesium, iron, zinc, nickel, and cobalt, have the merits of easy production and processing, mild stretchability, low modulus, good cytocompatibility, and corrosion resistance. $ ^{[98]} $ Titanium and its alloys are the most commonly used metallic materials for bone-defect repair because of their low weight, cytocompatibility, high friction coefficient, high porosity, and high resistance to corrosion. $ ^{[99]} $ Coating titanium medical implants with a thin layer of titanium dioxide ( $ TiO_{2} $) enhanced cell attachment, proliferation, and osseointegration. $ ^{[100]} $ An increasing number of studies have focused on the manufacture of 3D-printed porous metal scaffolds and the modification of metallic materials. 3D-printed titanium alloy scaffolds modified with human MSCs-derived exosomes can upregulate osteogenic miRNAs and promote osteogenic differentiation. $ ^{[101]} $ Exosome/porous $ Ti_{6}Al_{4}V $ composite scaffolds with a reduced elastic modulus exhibited a tighter combination with new bone, better osseointegration, and significantly promoted the formation of new bone in vivo. $ ^{[102]} $ Metal", "page_width": 1191, "page_height": 1565, "role": "body_paragraph", "role_confidence": 0.6, "evidence": ["default body_paragraph for text label"], "seed_role": "body_paragraph", "seed_confidence": 0.6, "seed_evidence": ["default body_paragraph for text label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 6, "page": 10, "raw_label": "text", "text": "Metals with excellent mechanical properties and load-bearing capacities are ideal for bone implantation and cardiovascular stents. Commonly used metallic materials, such as titanium, magnesium, iron, zinc, nickel, and cobalt, have the merits of easy production and processing, mild stretchability, low modulus, good cytocompatibility, and corrosion resistance. $ ^{[98]} $ Titanium and its alloys are the most commonly used metallic materials for bone-defect repair because of their low weight, cytocompatibility, high friction coefficient, high porosity, and high resistance to corrosion. $ ^{[99]} $ Coating titanium medical implants with a thin layer of titanium dioxide ( $ TiO_{2} $) enhanced cell attachment, proliferation, and osseointegration. $ ^{[100]} $ An increasing number of studies have focused on the manufacture of 3D-printed porous metal scaffolds and the modification of metallic materials. 3D-printed titanium alloy scaffolds modified with human MSCs-derived exosomes can upregulate osteogenic miRNAs and promote osteogenic differentiation. $ ^{[101]} $ Exosome/porous $ Ti_{6}Al_{4}V $ composite scaffolds with a reduced elastic modulus exhibited a tighter combination with new bone, better osseointegration, and significantly promoted the formation of new bone in vivo. $ ^{[102]} $ Metal", "bbox": [90, 1350, 582, 1440], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "Metals with excellent mechanical properties and load-bearing capacities are ideal for bone implantation and cardiovascular stents. Commonly used metallic materials, such as titanium, magnesium, iron, zinc, nickel, and cobalt, have the merits of easy production and processing, mild stretchability, low modulus, good cytocompatibility, and corrosion resistance. $ ^{[98]} $ Titanium and its alloys are the most commonly used metallic materials for bone-defect repair because of their low weight, cytocompatibility, high friction coefficient, high porosity, and high resistance to corrosion. $ ^{[99]} $ Coating titanium medical implants with a thin layer of titanium dioxide ( $ TiO_{2} $) enhanced cell attachment, proliferation, and osseointegration. $ ^{[100]} $ An increasing number of studies have focused on the manufacture of 3D-printed porous metal scaffolds and the modification of metallic materials. 3D-printed titanium alloy scaffolds modified with human MSCs-derived exosomes can upregulate osteogenic miRNAs and promote osteogenic differentiation. $ ^{[101]} $ Exosome/porous $ Ti_{6}Al_{4}V $ composite scaffolds with a reduced elastic modulus exhibited a tighter combination with new bone, better osseointegration, and significantly promoted the formation of new bone in vivo. $ ^{[102]} $ Metal"}, "layout_signature": {"width": 492, "width_bucket": 500, "height": 90, "left": 90, "top": 1350, "right": 582, "bottom": 1440, "x_center": 336.0, "x_center_bucket": 325, "y_center": 1395.0, "x_ratio": 0.2821, "y_ratio": 0.8914, "width_ratio": 0.4131, "height_ratio": 0.0575, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaPro-Regular", "bold": false, "italic": true, "span_count": 38}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_140", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 10, "block_id": 7, "raw_label": "text", "raw_order": 4, "bbox": [599, 1091, 1093, 1445], "text": "", "page_width": 1191, "page_height": 1565, "role": "ocr_text_missing", "role_confidence": 0.8, "evidence": ["ocr detected text region (raw_label=text) but no text extracted; no pdf backfill available"], "seed_role": "ocr_text_missing", "seed_confidence": 0.8, "seed_evidence": ["ocr detected text region (raw_label=text) but no text extracted; no pdf backfill available"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 7, "page": 10, "raw_label": "text", "text": "", "bbox": [599, 1091, 1093, 1445], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "empty", "raw_marker": null, "number": null, "kind": null, "normalized_text": ""}, "layout_signature": {"width": 494, "width_bucket": 500, "height": 354, "left": 599, "top": 1091, "right": 1093, "bottom": 1445, "x_center": 846.0, "x_center_bucket": 850, "y_center": 1268.0, "x_ratio": 0.7103, "y_ratio": 0.8102, "width_ratio": 0.4148, "height_ratio": 0.2262, "line_count": 1}, "span_signature": {"font_size": 8.64, "font_size_median": 8.97, "font_size_bucket": 8.5, "font_family_norm": "ScalaPro-Regular", "bold": false, "italic": true, "span_count": 165}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": "pdf_text_layer_fallback_rejected", "_ocr_raw_status": "missing_text_rejected", "_ocr_raw_error_type": "backfill_overlaps_existing_text_block", "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "_needs_pdf_fallback": true, "reading_band_id": "band_139", "display_cluster_candidate_id": "disp_27_0", "layout_region": "display_zone", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 10, "block_id": 8, "raw_label": "footer", "raw_order": null, "bbox": [94, 1487, 283, 1505], "text": "Small Methods 2024, 8, 2301283", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["footer label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["footer label"], "span_metadata": [{"size": 6.973800182342529, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 8, "page": 10, "raw_label": "footer", "text": "Small Methods 2024, 8, 2301283", "bbox": [94, 1487, 283, 1505], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "Small Methods 2024, 8, 2301283"}, "layout_signature": {"width": 189, "width_bucket": 200, "height": 18, "left": 94, "top": 1487, "right": 283, "bottom": 1505, "x_center": 188.5, "x_center_bucket": 200, "y_center": 1496.0, "x_ratio": 0.1583, "y_ratio": 0.9559, "width_ratio": 0.1587, "height_ratio": 0.0115, "line_count": 1}, "span_signature": {"font_size": 6.97, "font_size_median": 6.97, "font_size_bucket": 7.0, "font_family_norm": "ScalaSansPro-Italic", "bold": true, "italic": true, "span_count": 5}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_140", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 10, "block_id": 9, "raw_label": "footer", "raw_order": null, "bbox": [520, 1484, 663, 1507], "text": "2301283 (10 of 27)", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["footer label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["footer label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaSansPro-Bold", "flags": 20, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 9, "page": 10, "raw_label": "footer", "text": "2301283 (10 of 27)", "bbox": [520, 1484, 663, 1507], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_dot", "raw_marker": "2301283", "number": 2301283, "kind": "reference", "normalized_text": "2301283 (10 of 27)"}, "layout_signature": {"width": 143, "width_bucket": 150, "height": 23, "left": 520, "top": 1484, "right": 663, "bottom": 1507, "x_center": 591.5, "x_center_bucket": 600, "y_center": 1495.5, "x_ratio": 0.4966, "y_ratio": 0.9556, "width_ratio": 0.1201, "height_ratio": 0.0147, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaSansPro-Bold", "bold": true, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "reference_like", "style_family_authority": "reference_family_anchor", "reading_band_id": "band_138", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 10, "block_id": 10, "raw_label": "footer", "raw_order": null, "bbox": [931, 1487, 1090, 1506], "text": "© 2024 Wiley-VCH GmbH", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["footer label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["footer label"], "span_metadata": [{"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 10, "page": 10, "raw_label": "footer", "text": "© 2024 Wiley-VCH GmbH", "bbox": [931, 1487, 1090, 1506], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "© 2024 Wiley-VCH GmbH"}, "layout_signature": {"width": 159, "width_bucket": 150, "height": 19, "left": 931, "top": 1487, "right": 1090, "bottom": 1506, "x_center": 1010.5, "x_center_bucket": 1000, "y_center": 1496.5, "x_ratio": 0.8484, "y_ratio": 0.9562, "width_ratio": 0.1335, "height_ratio": 0.0121, "line_count": 1}, "span_signature": {"font_size": 6.97, "font_size_median": 6.97, "font_size_bucket": 7.0, "font_family_norm": "ScalaSansPro-Regular", "bold": false, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_141", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "hard", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 10, "block_id": 11, "raw_label": "aside_text", "raw_order": null, "bbox": [1153, 29, 1171, 1534], "text": "23669608, 2024, 8, Downloaded from https://onlinelibrary.wiley.com/doi/10.1002/snml.202301283 by Shandong University Library, Wiley Online Library on [18/02/2026]. See the Terms and Conditions (https://onlinelibrary.wiley.com/terms-and-conditions) on Wiley Online Library for rules of use; OA articles are governed by the applicable Creative Commons License.", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.95, "evidence": ["margin-band narrow/tall geometry; treated as noise"], "seed_role": "noise", "seed_confidence": 0.95, "seed_evidence": ["margin-band narrow/tall geometry; treated as noise"], "span_metadata": [{"size": 5.03000020980835, "font": "Times-Roman", "flags": 4, "color": 0, "dir": [0.0, 1.0], "wmode": 0}], "raw_observation": {"block_id": 11, "page": 10, "raw_label": "aside_text", "text": "23669608, 2024, 8, Downloaded from https://onlinelibrary.wiley.com/doi/10.1002/snml.202301283 by Shandong University Library, Wiley Online Library on [18/02/2026]. See the Terms and Conditions (https://onlinelibrary.wiley.com/terms-and-conditions) on Wiley Online Library for rules of use; OA articles are governed by the applicable Creative Commons License.", "bbox": [1153, 29, 1171, 1534], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "23669608, 2024, 8, Downloaded from https://onlinelibrary.wiley.com/doi/10.1002/snml.202301283 by Shandong University Library, Wiley Online Library on [18/02/2026]. See the Terms and Conditions (https://onlinelibrary.wiley.com/terms-and-conditions) on Wiley Online Library for rules of use; OA articles are governed by the applicable Creative Commons License."}, "layout_signature": {"width": 18, "width_bucket": 25, "height": 1505, "left": 1153, "top": 29, "right": 1171, "bottom": 1534, "x_center": 1162.0, "x_center_bucket": 1150, "y_center": 781.5, "x_ratio": 0.9757, "y_ratio": 0.4994, "width_ratio": 0.0151, "height_ratio": 0.9617, "line_count": 1}, "span_signature": {"font_size": 5.03, "font_size_median": 5.03, "font_size_bucket": 5.0, "font_family_norm": "Times-Roman", "bold": false, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_family_anchor", "reading_band_id": "band_142", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 11, "block_id": 0, "raw_label": "header", "raw_order": null, "bbox": [98, 46, 345, 117], "text": "ADVANCED\nSCIENCE NEWS\nwww.advancedsciencenews.com", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["header label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["header label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaSansPro-Bold", "flags": 20, "color": 255, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 0, "page": 11, "raw_label": "header", "text": "ADVANCED\nSCIENCE NEWS\nwww.advancedsciencenews.com", "bbox": [98, 46, 345, 117], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "ADVANCED\nSCIENCE NEWS\nwww.advancedsciencenews.com"}, "layout_signature": {"width": 247, "width_bucket": 250, "height": 71, "left": 98, "top": 46, "right": 345, "bottom": 117, "x_center": 221.5, "x_center_bucket": 225, "y_center": 81.5, "x_ratio": 0.186, "y_ratio": 0.0521, "width_ratio": 0.2074, "height_ratio": 0.0454, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaSansPro-Bold", "bold": true, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 11, "block_id": 1, "raw_label": "header", "raw_order": null, "bbox": [1003, 36, 1095, 97], "text": "small methods", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["header label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["header label"], "span_metadata": null, "raw_observation": {"block_id": 1, "page": 11, "raw_label": "header", "text": "small methods", "bbox": [1003, 36, 1095, 97], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "short_fragment", "raw_marker": "small methods", "number": null, "kind": "short_fragment", "normalized_text": "small methods"}, "layout_signature": {"width": 92, "width_bucket": 100, "height": 61, "left": 1003, "top": 36, "right": 1095, "bottom": 97, "x_center": 1049.0, "x_center_bucket": 1050, "y_center": 66.5, "x_ratio": 0.8808, "y_ratio": 0.0425, "width_ratio": 0.0772, "height_ratio": 0.039, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": true, "_container_bbox": [1005.7522789906125, 37.836628863963085, 1084.0337389451988, 91.04600210547972], "_container_text": "small methods", "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_142", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.6, "decision": "structured_insert_candidate", "evidence": ["visual_container", "narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 11, "block_id": 2, "raw_label": "header", "raw_order": null, "bbox": [902, 97, 1096, 117], "text": "www.small-methods.com", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["header label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["header label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaSansPro-Bold", "flags": 20, "color": 255, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 2, "page": 11, "raw_label": "header", "text": "www.small-methods.com", "bbox": [902, 97, 1096, 117], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "www.small-methods.com"}, "layout_signature": {"width": 194, "width_bucket": 200, "height": 20, "left": 902, "top": 97, "right": 1096, "bottom": 117, "x_center": 999.0, "x_center_bucket": 1000, "y_center": 107.0, "x_ratio": 0.8388, "y_ratio": 0.0684, "width_ratio": 0.1629, "height_ratio": 0.0128, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaSansPro-Bold", "bold": true, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_142", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 11, "block_id": 3, "raw_label": "text", "raw_order": 1, "bbox": [95, 149, 588, 610], "text": "ions released by metal degradation, such as magnesium, iron, zinc, and strontium, have important effects on bone healing by affecting the balance between bone cells and are regarded as biological factors in bone formation. $ ^{[103-105]} $ For example, magnesium ions can stimulate osteoblast activity, proliferation, and new bone formation and are excreted in urine, avoiding the toxicity caused by concentrated ions. $ ^{[106]} $ Various metal nanomaterials that are easily synthesized and modified have been reported to facilitate osteogenic differentiation. Gold nanoparticles (AuNPs) with different physicochemical characteristics can promote the osteogenic differentiation of MSCs through their interaction with cell membranes or cytoplasmic proteins. $ ^{[107,108]} $ Silver nanoparticles with antimicrobial and antiviral properties enhanced cell proliferation, cytoskeletal tension, and osteogenic differentiation in vitro, and promoted the formation of new bone in vivo. $ ^{[109]} $ However, most metallic materials lack biodegradability and require additional surgery to remove the implants after bone healing. Moreover, stress-shielding effects, and metal wear debris can lead to the production of toxic substances and a decline in bone density. It is difficult to introduce other osteoinductive biomaterials onto the surface of metal scaffolds.", "page_width": 1191, "page_height": 1565, "role": "body_paragraph", "role_confidence": 0.6, "evidence": ["default body_paragraph for text label"], "seed_role": "body_paragraph", "seed_confidence": 0.6, "seed_evidence": ["default body_paragraph for text label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 3, "page": 11, "raw_label": "text", "text": "ions released by metal degradation, such as magnesium, iron, zinc, and strontium, have important effects on bone healing by affecting the balance between bone cells and are regarded as biological factors in bone formation. $ ^{[103-105]} $ For example, magnesium ions can stimulate osteoblast activity, proliferation, and new bone formation and are excreted in urine, avoiding the toxicity caused by concentrated ions. $ ^{[106]} $ Various metal nanomaterials that are easily synthesized and modified have been reported to facilitate osteogenic differentiation. Gold nanoparticles (AuNPs) with different physicochemical characteristics can promote the osteogenic differentiation of MSCs through their interaction with cell membranes or cytoplasmic proteins. $ ^{[107,108]} $ Silver nanoparticles with antimicrobial and antiviral properties enhanced cell proliferation, cytoskeletal tension, and osteogenic differentiation in vitro, and promoted the formation of new bone in vivo. $ ^{[109]} $ However, most metallic materials lack biodegradability and require additional surgery to remove the implants after bone healing. Moreover, stress-shielding effects, and metal wear debris can lead to the production of toxic substances and a decline in bone density. It is difficult to introduce other osteoinductive biomaterials onto the surface of metal scaffolds.", "bbox": [95, 149, 588, 610], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "ions released by metal degradation, such as magnesium, iron, zinc, and strontium, have important effects on bone healing by affecting the balance between bone cells and are regarded as biological factors in bone formation. $ ^{[103-105]} $ For example, magnesium ions can stimulate osteoblast activity, proliferation, and new bone formation and are excreted in urine, avoiding the toxicity caused by concentrated ions. $ ^{[106]} $ Various metal nanomaterials that are easily synthesized and modified have been reported to facilitate osteogenic differentiation. Gold nanoparticles (AuNPs) with different physicochemical characteristics can promote the osteogenic differentiation of MSCs through their interaction with cell membranes or cytoplasmic proteins. $ ^{[107,108]} $ Silver nanoparticles with antimicrobial and antiviral properties enhanced cell proliferation, cytoskeletal tension, and osteogenic differentiation in vitro, and promoted the formation of new bone in vivo. $ ^{[109]} $ However, most metallic materials lack biodegradability and require additional surgery to remove the implants after bone healing. Moreover, stress-shielding effects, and metal wear debris can lead to the production of toxic substances and a decline in bone density. It is difficult to introduce other osteoinductive biomaterials onto the surface of metal scaffolds."}, "layout_signature": {"width": 493, "width_bucket": 500, "height": 461, "left": 95, "top": 149, "right": 588, "bottom": 610, "x_center": 341.5, "x_center_bucket": 350, "y_center": 379.5, "x_ratio": 0.2867, "y_ratio": 0.2425, "width_ratio": 0.4139, "height_ratio": 0.2946, "line_count": 1}, "span_signature": {"font_size": 8.79, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaPro-Regular", "bold": false, "italic": true, "span_count": 201}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_139", "display_cluster_candidate_id": "disp_27_0", "layout_region": "display_zone", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 11, "block_id": 4, "raw_label": "text", "raw_order": 2, "bbox": [95, 610, 588, 1226], "text": "Metal-organic frameworks (MOFs) with intramolecular pores and intrinsic bioactivity comprise metal ions and organic ligands. The large specific surface area of MOFs is conducive to cell adhesion and proliferation, and their diverse pore structures and porosities are suitable for loading and releasing biomolecules and antimicrobials. A MOF-coated magnesium alloy exhibited excellent bioactivity conducive to bone remodeling, and the MOF coating improved the hydrophilicity and corrosion resistance of the magnesium alloy. Furthermore, in vitro cytocompatibility results indicated that the MOF coating exhibited good biocompatibility. Previous studies have shown that MOFs could promote osteogenic differentiation in vitro. Zn-based MOF films prepared on porous titanium surfaces increased ALP activity, ECM mineralization, and expression of osteogenic markers in MG63 cells and inhibited the proliferation of Streptococcus mutans. $ ^{[110]} $ Magnesium-MOF74 exhibited good biocompatibility, anti-inflammatory, and antibacterial properties and promoted early osteogenesis and angiogenesis in vivo. $ ^{[111]} $ PLGA/Exo-Mg-GA MOF composite scaffolds steadily released exosomes and magnesium ions, promoted cell adhesion and proliferation, enhanced anti-inflammatory and angiogenic effects, and accelerated new bone formation (Figure 4A–C). $ ^{[112]} $ Asymmetric double-layer polycaprolactone/collagen (PCL/Col) membrane could be modified by MOF crystals, the MOF crystals can provide a pH-responsive release of $ Zn^{2+} $ ions, which facilitated the barrier layer functions to prevent the infiltration of fibrous connective tissue and enhance osteogenesis and angiogenesis in vitro (Figure 4D–F). $ ^{[113]} $", "page_width": 1191, "page_height": 1565, "role": "body_paragraph", "role_confidence": 0.6, "evidence": ["default body_paragraph for text label"], "seed_role": "body_paragraph", "seed_confidence": 0.6, "seed_evidence": ["default body_paragraph for text label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Italic", "flags": 6, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Italic", "flags": 6, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Italic", "flags": 6, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Bold", "flags": 20, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Bold", "flags": 20, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "STIXMath-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 4, "page": 11, "raw_label": "text", "text": "Metal-organic frameworks (MOFs) with intramolecular pores and intrinsic bioactivity comprise metal ions and organic ligands. The large specific surface area of MOFs is conducive to cell adhesion and proliferation, and their diverse pore structures and porosities are suitable for loading and releasing biomolecules and antimicrobials. A MOF-coated magnesium alloy exhibited excellent bioactivity conducive to bone remodeling, and the MOF coating improved the hydrophilicity and corrosion resistance of the magnesium alloy. Furthermore, in vitro cytocompatibility results indicated that the MOF coating exhibited good biocompatibility. Previous studies have shown that MOFs could promote osteogenic differentiation in vitro. Zn-based MOF films prepared on porous titanium surfaces increased ALP activity, ECM mineralization, and expression of osteogenic markers in MG63 cells and inhibited the proliferation of Streptococcus mutans. $ ^{[110]} $ Magnesium-MOF74 exhibited good biocompatibility, anti-inflammatory, and antibacterial properties and promoted early osteogenesis and angiogenesis in vivo. $ ^{[111]} $ PLGA/Exo-Mg-GA MOF composite scaffolds steadily released exosomes and magnesium ions, promoted cell adhesion and proliferation, enhanced anti-inflammatory and angiogenic effects, and accelerated new bone formation (Figure 4A–C). $ ^{[112]} $ Asymmetric double-layer polycaprolactone/collagen (PCL/Col) membrane could be modified by MOF crystals, the MOF crystals can provide a pH-responsive release of $ Zn^{2+} $ ions, which facilitated the barrier layer functions to prevent the infiltration of fibrous connective tissue and enhance osteogenesis and angiogenesis in vitro (Figure 4D–F). $ ^{[113]} $", "bbox": [95, 610, 588, 1226], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "Metal-organic frameworks (MOFs) with intramolecular pores and intrinsic bioactivity comprise metal ions and organic ligands. The large specific surface area of MOFs is conducive to cell adhesion and proliferation, and their diverse pore structures and porosities are suitable for loading and releasing biomolecules and antimicrobials. A MOF-coated magnesium alloy exhibited excellent bioactivity conducive to bone remodeling, and the MOF coating improved the hydrophilicity and corrosion resistance of the magnesium alloy. Furthermore, in vitro cytocompatibility results indicated that the MOF coating exhibited good biocompatibility. Previous studies have shown that MOFs could promote osteogenic differentiation in vitro. Zn-based MOF films prepared on porous titanium surfaces increased ALP activity, ECM mineralization, and expression of osteogenic markers in MG63 cells and inhibited the proliferation of Streptococcus mutans. $ ^{[110]} $ Magnesium-MOF74 exhibited good biocompatibility, anti-inflammatory, and antibacterial properties and promoted early osteogenesis and angiogenesis in vivo. $ ^{[111]} $ PLGA/Exo-Mg-GA MOF composite scaffolds steadily released exosomes and magnesium ions, promoted cell adhesion and proliferation, enhanced anti-inflammatory and angiogenic effects, and accelerated new bone formation (Figure 4A–C). $ ^{[112]} $ Asymmetric double-layer polycaprolactone/collagen (PCL/Col) membrane could be modified by MOF crystals, the MOF crystals can provide a pH-responsive release of $ Zn^{2+} $ ions, which facilitated the barrier layer functions to prevent the infiltration of fibrous connective tissue and enhance osteogenesis and angiogenesis in vitro (Figure 4D–F). $ ^{[113]} $"}, "layout_signature": {"width": 493, "width_bucket": 500, "height": 616, "left": 95, "top": 610, "right": 588, "bottom": 1226, "x_center": 341.5, "x_center_bucket": 350, "y_center": 918.0, "x_ratio": 0.2867, "y_ratio": 0.5866, "width_ratio": 0.4139, "height_ratio": 0.3936, "line_count": 1}, "span_signature": {"font_size": 8.83, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaPro-Regular", "bold": true, "italic": true, "span_count": 330}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_140", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 11, "block_id": 5, "raw_label": "text", "raw_order": 3, "bbox": [95, 1223, 588, 1445], "text": "There are several methods for preparing MOFs, including solvothermal synthesis (mixing metal ions and organic ligands in an organic solvent, heating to a certain temperature, and forming crystals), hydrothermal synthesis (mixing metal ions and organic ligands in water, heating to a certain temperature, and forming crystals), vapor diffusion synthesis (mixing metal ions and organic ligands in the gas phase, and forming crystals through diffusion reaction), water-thermal synthesis (mixing metal ions and organic ligands in water, heating to a certain temperature, and forming crystals), and water-thermal-solvent synthesis (mixing metal ions and organic ligands in water and organic solvents, heating to a certain temperature, and forming crystals). Each of these methods has its own advantages and disadvantages, and the specific method chosen depends on the properties and application scenarios of the desired MOFs. The preparation method of MOFs has a significant impact on their properties, such as crystal structure, pore size, porosity, surface area, stability, and biocompatibility. For example, MOFs prepared by solvothermal synthesis have the characteristics of complete crystal structure, adjustable pore size, large porosity, and large surface area, but require the use of organic solvents, which cause some environmental pollution. MOFs prepared by hydrothermal synthesis have the advantages of simple preparation and no need for organic solvents, but the pore size and porosity are difficult to control. Therefore, choosing the appropriate preparation method is very important for preparing MOFs with specific properties.", "page_width": 1191, "page_height": 1565, "role": "body_paragraph", "role_confidence": 0.6, "evidence": ["default body_paragraph for text label"], "seed_role": "body_paragraph", "seed_confidence": 0.6, "seed_evidence": ["default body_paragraph for text label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 5, "page": 11, "raw_label": "text", "text": "There are several methods for preparing MOFs, including solvothermal synthesis (mixing metal ions and organic ligands in an organic solvent, heating to a certain temperature, and forming crystals), hydrothermal synthesis (mixing metal ions and organic ligands in water, heating to a certain temperature, and forming crystals), vapor diffusion synthesis (mixing metal ions and organic ligands in the gas phase, and forming crystals through diffusion reaction), water-thermal synthesis (mixing metal ions and organic ligands in water, heating to a certain temperature, and forming crystals), and water-thermal-solvent synthesis (mixing metal ions and organic ligands in water and organic solvents, heating to a certain temperature, and forming crystals). Each of these methods has its own advantages and disadvantages, and the specific method chosen depends on the properties and application scenarios of the desired MOFs. The preparation method of MOFs has a significant impact on their properties, such as crystal structure, pore size, porosity, surface area, stability, and biocompatibility. For example, MOFs prepared by solvothermal synthesis have the characteristics of complete crystal structure, adjustable pore size, large porosity, and large surface area, but require the use of organic solvents, which cause some environmental pollution. MOFs prepared by hydrothermal synthesis have the advantages of simple preparation and no need for organic solvents, but the pore size and porosity are difficult to control. Therefore, choosing the appropriate preparation method is very important for preparing MOFs with specific properties.", "bbox": [95, 1223, 588, 1445], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "There are several methods for preparing MOFs, including solvothermal synthesis (mixing metal ions and organic ligands in an organic solvent, heating to a certain temperature, and forming crystals), hydrothermal synthesis (mixing metal ions and organic ligands in water, heating to a certain temperature, and forming crystals), vapor diffusion synthesis (mixing metal ions and organic ligands in the gas phase, and forming crystals through diffusion reaction), water-thermal synthesis (mixing metal ions and organic ligands in water, heating to a certain temperature, and forming crystals), and water-thermal-solvent synthesis (mixing metal ions and organic ligands in water and organic solvents, heating to a certain temperature, and forming crystals). Each of these methods has its own advantages and disadvantages, and the specific method chosen depends on the properties and application scenarios of the desired MOFs. The preparation method of MOFs has a significant impact on their properties, such as crystal structure, pore size, porosity, surface area, stability, and biocompatibility. For example, MOFs prepared by solvothermal synthesis have the characteristics of complete crystal structure, adjustable pore size, large porosity, and large surface area, but require the use of organic solvents, which cause some environmental pollution. MOFs prepared by hydrothermal synthesis have the advantages of simple preparation and no need for organic solvents, but the pore size and porosity are difficult to control. Therefore, choosing the appropriate preparation method is very important for preparing MOFs with specific properties."}, "layout_signature": {"width": 493, "width_bucket": 500, "height": 222, "left": 95, "top": 1223, "right": 588, "bottom": 1445, "x_center": 341.5, "x_center_bucket": 350, "y_center": 1334.0, "x_ratio": 0.2867, "y_ratio": 0.8524, "width_ratio": 0.4139, "height_ratio": 0.1419, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaPro-Regular", "bold": false, "italic": true, "span_count": 106}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_139", "display_cluster_candidate_id": "disp_27_0", "layout_region": "display_zone", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 11, "block_id": 6, "raw_label": "text", "raw_order": 4, "bbox": [605, 149, 1099, 503], "text": "", "page_width": 1191, "page_height": 1565, "role": "ocr_text_missing", "role_confidence": 0.8, "evidence": ["ocr detected text region (raw_label=text) but no text extracted; no pdf backfill available"], "seed_role": "ocr_text_missing", "seed_confidence": 0.8, "seed_evidence": ["ocr detected text region (raw_label=text) but no text extracted; no pdf backfill available"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 6, "page": 11, "raw_label": "text", "text": "", "bbox": [605, 149, 1099, 503], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "empty", "raw_marker": null, "number": null, "kind": null, "normalized_text": ""}, "layout_signature": {"width": 494, "width_bucket": 500, "height": 354, "left": 605, "top": 149, "right": 1099, "bottom": 503, "x_center": 852.0, "x_center_bucket": 850, "y_center": 326.0, "x_ratio": 0.7154, "y_ratio": 0.2083, "width_ratio": 0.4148, "height_ratio": 0.2262, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaPro-Regular", "bold": false, "italic": true, "span_count": 98}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": "pdf_text_layer_fallback_rejected", "_ocr_raw_status": "missing_text_rejected", "_ocr_raw_error_type": "backfill_overlaps_existing_text_block", "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "_needs_pdf_fallback": true, "reading_band_id": "band_140", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 11, "block_id": 7, "raw_label": "paragraph_title", "raw_order": 5, "bbox": [607, 565, 844, 588], "text": "2.4. Layered Double Hydroxide", "page_width": 1191, "page_height": 1565, "role": "subsection_heading", "role_confidence": 0.85, "evidence": ["paragraph_title label with numbering: 2.4. Layered Double Hydroxide"], "seed_role": "subsection_heading", "seed_confidence": 0.85, "seed_evidence": ["paragraph_title label with numbering: 2.4. Layered Double Hydroxide"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaSansPro-Bold", "flags": 20, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 7, "page": 11, "raw_label": "paragraph_title", "text": "2.4. Layered Double Hydroxide", "bbox": [607, 565, 844, 588], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "heading_numbered", "raw_marker": "2.4", "number": "2.4", "kind": "heading", "normalized_text": "2.4. Layered Double Hydroxide"}, "layout_signature": {"width": 237, "width_bucket": 225, "height": 23, "left": 607, "top": 565, "right": 844, "bottom": 588, "x_center": 725.5, "x_center_bucket": 725, "y_center": 576.5, "x_ratio": 0.6092, "y_ratio": 0.3684, "width_ratio": 0.199, "height_ratio": 0.0147, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaSansPro-Bold", "bold": true, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_139", "display_cluster_candidate_id": "disp_27_0", "layout_region": "display_zone", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "accepted_heading", "role_evidence": ["heading verified by heading artifact"]}
+{"paper_id": "2HEUD5P9", "page": 11, "block_id": 8, "raw_label": "text", "raw_order": 6, "bbox": [604, 609, 1098, 1094], "text": "Several studies have focused on the application of layered double hydroxide (LDH) in the biomedical field, such as drug/gene delivery, bone repair and regeneration, and biological functional surface modification, owing to its excellent biocompatibility. In addition, LDH exhibits anti-inflammatory and immunoregulatory properties in the tissue microenvironment. $ ^{[114]} $ As the transport vehicle of the osteoinductive miRNA let-7d, LDH synergistically regulate BMSCs toward the osteoblastic lineage, The LDH/let-7d complex resulted in a better induction of osteogenesis than LDH alone (Figure 5A,B). $ ^{[115]} $ The corrosion resistance and biocompatibility of magnesium alloys are enhanced by the addition of MgAl-LDH, and this composite exhibits superior osteogenic differentiation, angiogenic capacity, and anti-inflammatory effects (Figure 5C–E). $ ^{[116]} $ The presence of LDH nanoparticles in $ \\beta $-TCP nanocomposite granules increased the compressive modulus. $ ^{[117]} $ LDH-chitosan porous scaffolds loaded with PFT $ \\alpha $ significantly promoted the osteogenic differentiation in vitro, and accelerated bone tissue repair in cranial defect model rats. $ ^{[118]} $ Gallium-strontium LDH films on titanium substrates have strong antibacterial capabilities, promote the differentiation of osteogenic cells, stimulate ALP activity and collagen secretion, and enhance osseointegration capacity. $ ^{[119]} $", "page_width": 1191, "page_height": 1565, "role": "body_paragraph", "role_confidence": 0.6, "evidence": ["default body_paragraph for text label"], "seed_role": "body_paragraph", "seed_confidence": 0.6, "seed_evidence": ["default body_paragraph for text label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Bold", "flags": 20, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Bold", "flags": 20, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Bold", "flags": 20, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "STIXMath-Italic", "flags": 6, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "STIXMath-Italic", "flags": 6, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "STIXMath-Italic", "flags": 6, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 8, "page": 11, "raw_label": "text", "text": "Several studies have focused on the application of layered double hydroxide (LDH) in the biomedical field, such as drug/gene delivery, bone repair and regeneration, and biological functional surface modification, owing to its excellent biocompatibility. In addition, LDH exhibits anti-inflammatory and immunoregulatory properties in the tissue microenvironment. $ ^{[114]} $ As the transport vehicle of the osteoinductive miRNA let-7d, LDH synergistically regulate BMSCs toward the osteoblastic lineage, The LDH/let-7d complex resulted in a better induction of osteogenesis than LDH alone (Figure 5A,B). $ ^{[115]} $ The corrosion resistance and biocompatibility of magnesium alloys are enhanced by the addition of MgAl-LDH, and this composite exhibits superior osteogenic differentiation, angiogenic capacity, and anti-inflammatory effects (Figure 5C–E). $ ^{[116]} $ The presence of LDH nanoparticles in $ \\beta $-TCP nanocomposite granules increased the compressive modulus. $ ^{[117]} $ LDH-chitosan porous scaffolds loaded with PFT $ \\alpha $ significantly promoted the osteogenic differentiation in vitro, and accelerated bone tissue repair in cranial defect model rats. $ ^{[118]} $ Gallium-strontium LDH films on titanium substrates have strong antibacterial capabilities, promote the differentiation of osteogenic cells, stimulate ALP activity and collagen secretion, and enhance osseointegration capacity. $ ^{[119]} $", "bbox": [604, 609, 1098, 1094], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "Several studies have focused on the application of layered double hydroxide (LDH) in the biomedical field, such as drug/gene delivery, bone repair and regeneration, and biological functional surface modification, owing to its excellent biocompatibility. In addition, LDH exhibits anti-inflammatory and immunoregulatory properties in the tissue microenvironment. $ ^{[114]} $ As the transport vehicle of the osteoinductive miRNA let-7d, LDH synergistically regulate BMSCs toward the osteoblastic lineage, The LDH/let-7d complex resulted in a better induction of osteogenesis than LDH alone (Figure 5A,B). $ ^{[115]} $ The corrosion resistance and biocompatibility of magnesium alloys are enhanced by the addition of MgAl-LDH, and this composite exhibits superior osteogenic differentiation, angiogenic capacity, and anti-inflammatory effects (Figure 5C–E). $ ^{[116]} $ The presence of LDH nanoparticles in $ \\beta $-TCP nanocomposite granules increased the compressive modulus. $ ^{[117]} $ LDH-chitosan porous scaffolds loaded with PFT $ \\alpha $ significantly promoted the osteogenic differentiation in vitro, and accelerated bone tissue repair in cranial defect model rats. $ ^{[118]} $ Gallium-strontium LDH films on titanium substrates have strong antibacterial capabilities, promote the differentiation of osteogenic cells, stimulate ALP activity and collagen secretion, and enhance osseointegration capacity. $ ^{[119]} $"}, "layout_signature": {"width": 494, "width_bucket": 500, "height": 485, "left": 604, "top": 609, "right": 1098, "bottom": 1094, "x_center": 851.0, "x_center_bucket": 850, "y_center": 851.5, "x_ratio": 0.7145, "y_ratio": 0.5441, "width_ratio": 0.4148, "height_ratio": 0.3099, "line_count": 1}, "span_signature": {"font_size": 8.74, "font_size_median": 8.97, "font_size_bucket": 8.5, "font_family_norm": "ScalaPro-Regular", "bold": true, "italic": true, "span_count": 237}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_140", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 11, "block_id": 9, "raw_label": "text", "raw_order": 7, "bbox": [605, 1091, 1098, 1446], "text": "Multifunctional layered SrFe₁₂O₁₉-LDH/chitosan scaffolds composed of SrFe₁₂O₁₉ nanoparticles, LDH nanoparticles, and bioactive chitosan can inhibit bone resorption in osteoclasts and the release of proinflammatory factors by magnesium ions from LDH nanoparticles. Strontium ions released from this scaffold promoted osteoblast proliferation and bone mineralization (Figure 5F–H).[120] The surface functionalization of MgAlEu-LDH nanosheets on a porous HAP scaffold effectively promoted cell adhesion, osteogenic differentiation, and vascular regeneration in vitro and accelerated new bone formation in vivo.[121] The inclusion of LDH in the PCL scaffold enhanced the mechanical strength and compressive modulus and improved cell viability, proliferation, and adhesion. In addition, LDH increased the expression of osteogenic markers and mineral deposition.[122] Black Mn-containing LDH nanosheet-modified Mg-based implants was developed for integration of biodegradation.", "page_width": 1191, "page_height": 1565, "role": "body_paragraph", "role_confidence": 0.6, "evidence": ["default body_paragraph for text label"], "seed_role": "body_paragraph", "seed_confidence": 0.6, "seed_evidence": ["default body_paragraph for text label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 9, "page": 11, "raw_label": "text", "text": "Multifunctional layered SrFe₁₂O₁₉-LDH/chitosan scaffolds composed of SrFe₁₂O₁₉ nanoparticles, LDH nanoparticles, and bioactive chitosan can inhibit bone resorption in osteoclasts and the release of proinflammatory factors by magnesium ions from LDH nanoparticles. Strontium ions released from this scaffold promoted osteoblast proliferation and bone mineralization (Figure 5F–H).[120] The surface functionalization of MgAlEu-LDH nanosheets on a porous HAP scaffold effectively promoted cell adhesion, osteogenic differentiation, and vascular regeneration in vitro and accelerated new bone formation in vivo.[121] The inclusion of LDH in the PCL scaffold enhanced the mechanical strength and compressive modulus and improved cell viability, proliferation, and adhesion. In addition, LDH increased the expression of osteogenic markers and mineral deposition.[122] Black Mn-containing LDH nanosheet-modified Mg-based implants was developed for integration of biodegradation.", "bbox": [605, 1091, 1098, 1446], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "Multifunctional layered SrFe₁₂O₁₉-LDH/chitosan scaffolds composed of SrFe₁₂O₁₉ nanoparticles, LDH nanoparticles, and bioactive chitosan can inhibit bone resorption in osteoclasts and the release of proinflammatory factors by magnesium ions from LDH nanoparticles. Strontium ions released from this scaffold promoted osteoblast proliferation and bone mineralization (Figure 5F–H).[120] The surface functionalization of MgAlEu-LDH nanosheets on a porous HAP scaffold effectively promoted cell adhesion, osteogenic differentiation, and vascular regeneration in vitro and accelerated new bone formation in vivo.[121] The inclusion of LDH in the PCL scaffold enhanced the mechanical strength and compressive modulus and improved cell viability, proliferation, and adhesion. In addition, LDH increased the expression of osteogenic markers and mineral deposition.[122] Black Mn-containing LDH nanosheet-modified Mg-based implants was developed for integration of biodegradation."}, "layout_signature": {"width": 493, "width_bucket": 500, "height": 355, "left": 605, "top": 1091, "right": 1098, "bottom": 1446, "x_center": 851.5, "x_center_bucket": 850, "y_center": 1268.5, "x_ratio": 0.7149, "y_ratio": 0.8105, "width_ratio": 0.4139, "height_ratio": 0.2268, "line_count": 1}, "span_signature": {"font_size": 8.7, "font_size_median": 8.97, "font_size_bucket": 8.5, "font_family_norm": "ScalaPro-Regular", "bold": false, "italic": true, "span_count": 147}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_138", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 11, "block_id": 10, "raw_label": "footer", "raw_order": null, "bbox": [99, 1487, 289, 1505], "text": "Small Methods 2024, 8, 2301283", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["footer label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["footer label"], "span_metadata": [{"size": 6.973800182342529, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 10, "page": 11, "raw_label": "footer", "text": "Small Methods 2024, 8, 2301283", "bbox": [99, 1487, 289, 1505], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "Small Methods 2024, 8, 2301283"}, "layout_signature": {"width": 190, "width_bucket": 200, "height": 18, "left": 99, "top": 1487, "right": 289, "bottom": 1505, "x_center": 194.0, "x_center_bucket": 200, "y_center": 1496.0, "x_ratio": 0.1629, "y_ratio": 0.9559, "width_ratio": 0.1595, "height_ratio": 0.0115, "line_count": 1}, "span_signature": {"font_size": 6.97, "font_size_median": 6.97, "font_size_bucket": 7.0, "font_family_norm": "ScalaSansPro-Italic", "bold": true, "italic": true, "span_count": 5}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_141", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "hard", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 11, "block_id": 11, "raw_label": "footer", "raw_order": null, "bbox": [526, 1483, 669, 1508], "text": "2301283 (11 of 27)", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["footer label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["footer label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaSansPro-Bold", "flags": 20, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 11, "page": 11, "raw_label": "footer", "text": "2301283 (11 of 27)", "bbox": [526, 1483, 669, 1508], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_dot", "raw_marker": "2301283", "number": 2301283, "kind": "reference", "normalized_text": "2301283 (11 of 27)"}, "layout_signature": {"width": 143, "width_bucket": 150, "height": 25, "left": 526, "top": 1483, "right": 669, "bottom": 1508, "x_center": 597.5, "x_center_bucket": 600, "y_center": 1495.5, "x_ratio": 0.5017, "y_ratio": 0.9556, "width_ratio": 0.1201, "height_ratio": 0.016, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaSansPro-Bold", "bold": true, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "reference_like", "style_family_authority": "reference_family_anchor", "reading_band_id": "band_142", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 11, "block_id": 12, "raw_label": "footer", "raw_order": null, "bbox": [937, 1486, 1096, 1506], "text": "© 2024 Wiley-VCH GmbH", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["footer label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["footer label"], "span_metadata": [{"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 12, "page": 11, "raw_label": "footer", "text": "© 2024 Wiley-VCH GmbH", "bbox": [937, 1486, 1096, 1506], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "© 2024 Wiley-VCH GmbH"}, "layout_signature": {"width": 159, "width_bucket": 150, "height": 20, "left": 937, "top": 1486, "right": 1096, "bottom": 1506, "x_center": 1016.5, "x_center_bucket": 1025, "y_center": 1496.0, "x_ratio": 0.8535, "y_ratio": 0.9559, "width_ratio": 0.1335, "height_ratio": 0.0128, "line_count": 1}, "span_signature": {"font_size": 6.97, "font_size_median": 6.97, "font_size_bucket": 7.0, "font_family_norm": "ScalaSansPro-Regular", "bold": false, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_142", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 11, "block_id": 13, "raw_label": "aside_text", "raw_order": null, "bbox": [1154, 30, 1171, 1534], "text": "23699608, 2024, 8, Downloaded from https://onlinelibrary.wiley.com/doi/10.1002/smkt.202301283 by Shandong University Library, Wiley Online Library on [18/02/2026]. See the Terms and Conditions (https://onlinelibrary.wiley.com/terms-and-conditions) on Wiley Online Library for rules of use; OA articles are governed by the applicable Creative Commons License.", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.95, "evidence": ["margin-band narrow/tall geometry; treated as noise"], "seed_role": "noise", "seed_confidence": 0.95, "seed_evidence": ["margin-band narrow/tall geometry; treated as noise"], "span_metadata": [{"size": 5.03000020980835, "font": "Times-Roman", "flags": 4, "color": 0, "dir": [0.0, 1.0], "wmode": 0}], "raw_observation": {"block_id": 13, "page": 11, "raw_label": "aside_text", "text": "23699608, 2024, 8, Downloaded from https://onlinelibrary.wiley.com/doi/10.1002/smkt.202301283 by Shandong University Library, Wiley Online Library on [18/02/2026]. See the Terms and Conditions (https://onlinelibrary.wiley.com/terms-and-conditions) on Wiley Online Library for rules of use; OA articles are governed by the applicable Creative Commons License.", "bbox": [1154, 30, 1171, 1534], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "23699608, 2024, 8, Downloaded from https://onlinelibrary.wiley.com/doi/10.1002/smkt.202301283 by Shandong University Library, Wiley Online Library on [18/02/2026]. See the Terms and Conditions (https://onlinelibrary.wiley.com/terms-and-conditions) on Wiley Online Library for rules of use; OA articles are governed by the applicable Creative Commons License."}, "layout_signature": {"width": 17, "width_bucket": 25, "height": 1504, "left": 1154, "top": 30, "right": 1171, "bottom": 1534, "x_center": 1162.5, "x_center_bucket": 1150, "y_center": 782.0, "x_ratio": 0.9761, "y_ratio": 0.4997, "width_ratio": 0.0143, "height_ratio": 0.961, "line_count": 1}, "span_signature": {"font_size": 5.03, "font_size_median": 5.03, "font_size_bucket": 5.0, "font_family_norm": "Times-Roman", "bold": false, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_family_anchor", "reading_band_id": "band_136", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 12, "block_id": 0, "raw_label": "header", "raw_order": null, "bbox": [91, 45, 340, 117], "text": "ADVANCED\nSCIENCE NEWS\nwww.advancedsciencenews.com", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["header label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["header label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaSansPro-Bold", "flags": 20, "color": 255, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 0, "page": 12, "raw_label": "header", "text": "ADVANCED\nSCIENCE NEWS\nwww.advancedsciencenews.com", "bbox": [91, 45, 340, 117], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "ADVANCED\nSCIENCE NEWS\nwww.advancedsciencenews.com"}, "layout_signature": {"width": 249, "width_bucket": 250, "height": 72, "left": 91, "top": 45, "right": 340, "bottom": 117, "x_center": 215.5, "x_center_bucket": 225, "y_center": 81.0, "x_ratio": 0.1809, "y_ratio": 0.0518, "width_ratio": 0.2091, "height_ratio": 0.046, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaSansPro-Bold", "bold": true, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 12, "block_id": 1, "raw_label": "header_image", "raw_order": null, "bbox": [894, 36, 1092, 117], "text": "", "page_width": 1191, "page_height": 1565, "role": "unknown_structural", "role_confidence": 0.2, "evidence": ["unrecognized label 'header_image'"], "seed_role": "unknown_structural", "seed_confidence": 0.2, "seed_evidence": ["unrecognized label 'header_image'"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaSansPro-Bold", "flags": 20, "color": 255, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 1, "page": 12, "raw_label": "header_image", "text": "", "bbox": [894, 36, 1092, 117], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "empty", "raw_marker": null, "number": null, "kind": null, "normalized_text": ""}, "layout_signature": {"width": 198, "width_bucket": 200, "height": 81, "left": 894, "top": 36, "right": 1092, "bottom": 117, "x_center": 993.0, "x_center_bucket": 1000, "y_center": 76.5, "x_ratio": 0.8338, "y_ratio": 0.0489, "width_ratio": 0.1662, "height_ratio": 0.0518, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaSansPro-Bold", "bold": true, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": true, "zone": "body_zone", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_142", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["non-structural role accepted"]}
+{"paper_id": "2HEUD5P9", "page": 12, "block_id": 2, "raw_label": "figure_title", "raw_order": null, "bbox": [102, 162, 145, 193], "text": "(A)", "page_width": 1191, "page_height": 1565, "role": "figure_inner_text", "role_confidence": 0.9, "evidence": ["panel label / figure inner text: (A)"], "seed_role": "figure_inner_text", "seed_confidence": 0.9, "seed_evidence": ["panel label / figure inner text: (A)"], "span_metadata": null, "raw_observation": {"block_id": 2, "page": 12, "raw_label": "figure_title", "text": "(A)", "bbox": [102, 162, 145, 193], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "panel_label", "raw_marker": "(A)", "number": null, "kind": "panel_label", "normalized_text": "(A)"}, "layout_signature": {"width": 43, "width_bucket": 50, "height": 31, "left": 102, "top": 162, "right": 145, "bottom": 193, "x_center": 123.5, "x_center_bucket": 125, "y_center": 177.5, "x_ratio": 0.1037, "y_ratio": 0.1134, "width_ratio": 0.0361, "height_ratio": 0.0198, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "display_zone", "style_family": "legend_like", "style_family_authority": "figure_marker", "reading_band_id": "band_142", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 12, "block_id": 3, "raw_label": "image", "raw_order": null, "bbox": [155, 147, 1087, 407], "text": "", "page_width": 1191, "page_height": 1565, "role": "media_asset", "role_confidence": 0.85, "evidence": ["media label: image"], "seed_role": "media_asset", "seed_confidence": 0.85, "seed_evidence": ["media label: image"], "span_metadata": null, "raw_observation": {"block_id": 3, "page": 12, "raw_label": "image", "text": "", "bbox": [155, 147, 1087, 407], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "empty", "raw_marker": null, "number": null, "kind": null, "normalized_text": ""}, "layout_signature": {"width": 932, "width_bucket": 925, "height": 260, "left": 155, "top": 147, "right": 1087, "bottom": 407, "x_center": 621.0, "x_center_bucket": 625, "y_center": 277.0, "x_ratio": 0.5214, "y_ratio": 0.177, "width_ratio": 0.7825, "height_ratio": 0.1661, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_139", "display_cluster_candidate_id": "disp_27_0", "layout_region": "display_zone", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.0, "decision": "body", "evidence": []}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"], "asset_family_hint": "figure_like", "asset_family_confidence": 0.7, "asset_family_evidence": ["raw_label:image"]}
+{"paper_id": "2HEUD5P9", "page": 12, "block_id": 4, "raw_label": "figure_title", "raw_order": null, "bbox": [103, 408, 143, 439], "text": "(B)", "page_width": 1191, "page_height": 1565, "role": "figure_inner_text", "role_confidence": 0.9, "evidence": ["panel label / figure inner text: (B)"], "seed_role": "figure_inner_text", "seed_confidence": 0.9, "seed_evidence": ["panel label / figure inner text: (B)"], "span_metadata": null, "raw_observation": {"block_id": 4, "page": 12, "raw_label": "figure_title", "text": "(B)", "bbox": [103, 408, 143, 439], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "panel_label", "raw_marker": "(B)", "number": null, "kind": "panel_label", "normalized_text": "(B)"}, "layout_signature": {"width": 40, "width_bucket": 50, "height": 31, "left": 103, "top": 408, "right": 143, "bottom": 439, "x_center": 123.0, "x_center_bucket": 125, "y_center": 423.5, "x_ratio": 0.1033, "y_ratio": 0.2706, "width_ratio": 0.0336, "height_ratio": 0.0198, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "display_zone", "style_family": "legend_like", "style_family_authority": "figure_marker", "reading_band_id": "band_140", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 12, "block_id": 5, "raw_label": "image", "raw_order": null, "bbox": [122, 419, 1071, 617], "text": "", "page_width": 1191, "page_height": 1565, "role": "media_asset", "role_confidence": 0.85, "evidence": ["media label: image"], "seed_role": "media_asset", "seed_confidence": 0.85, "seed_evidence": ["media label: image"], "span_metadata": null, "raw_observation": {"block_id": 5, "page": 12, "raw_label": "image", "text": "", "bbox": [122, 419, 1071, 617], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "empty", "raw_marker": null, "number": null, "kind": null, "normalized_text": ""}, "layout_signature": {"width": 949, "width_bucket": 950, "height": 198, "left": 122, "top": 419, "right": 1071, "bottom": 617, "x_center": 596.5, "x_center_bucket": 600, "y_center": 518.0, "x_ratio": 0.5008, "y_ratio": 0.331, "width_ratio": 0.7968, "height_ratio": 0.1265, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_139", "display_cluster_candidate_id": "disp_27_0", "layout_region": "display_zone", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.0, "decision": "body", "evidence": []}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"], "asset_family_hint": "figure_like", "asset_family_confidence": 0.7, "asset_family_evidence": ["raw_label:image"]}
+{"paper_id": "2HEUD5P9", "page": 12, "block_id": 6, "raw_label": "figure_title", "raw_order": null, "bbox": [99, 609, 139, 642], "text": "(C)", "page_width": 1191, "page_height": 1565, "role": "figure_inner_text", "role_confidence": 0.9, "evidence": ["panel label / figure inner text: (C)"], "seed_role": "figure_inner_text", "seed_confidence": 0.9, "seed_evidence": ["panel label / figure inner text: (C)"], "span_metadata": null, "raw_observation": {"block_id": 6, "page": 12, "raw_label": "figure_title", "text": "(C)", "bbox": [99, 609, 139, 642], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "panel_label", "raw_marker": "(C)", "number": null, "kind": "panel_label", "normalized_text": "(C)"}, "layout_signature": {"width": 40, "width_bucket": 50, "height": 33, "left": 99, "top": 609, "right": 139, "bottom": 642, "x_center": 119.0, "x_center_bucket": 125, "y_center": 625.5, "x_ratio": 0.0999, "y_ratio": 0.3997, "width_ratio": 0.0336, "height_ratio": 0.0211, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "display_zone", "style_family": "legend_like", "style_family_authority": "figure_marker", "reading_band_id": "band_140", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 12, "block_id": 7, "raw_label": "image", "raw_order": null, "bbox": [138, 631, 1071, 802], "text": "", "page_width": 1191, "page_height": 1565, "role": "media_asset", "role_confidence": 0.85, "evidence": ["media label: image"], "seed_role": "media_asset", "seed_confidence": 0.85, "seed_evidence": ["media label: image"], "span_metadata": null, "raw_observation": {"block_id": 7, "page": 12, "raw_label": "image", "text": "", "bbox": [138, 631, 1071, 802], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "empty", "raw_marker": null, "number": null, "kind": null, "normalized_text": ""}, "layout_signature": {"width": 933, "width_bucket": 925, "height": 171, "left": 138, "top": 631, "right": 1071, "bottom": 802, "x_center": 604.5, "x_center_bucket": 600, "y_center": 716.5, "x_ratio": 0.5076, "y_ratio": 0.4578, "width_ratio": 0.7834, "height_ratio": 0.1093, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_139", "display_cluster_candidate_id": "disp_27_0", "layout_region": "display_zone", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.0, "decision": "body", "evidence": []}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"], "asset_family_hint": "figure_like", "asset_family_confidence": 0.7, "asset_family_evidence": ["raw_label:image"]}
+{"paper_id": "2HEUD5P9", "page": 12, "block_id": 8, "raw_label": "figure_title", "raw_order": null, "bbox": [107, 820, 150, 851], "text": "(D)", "page_width": 1191, "page_height": 1565, "role": "figure_inner_text", "role_confidence": 0.9, "evidence": ["panel label / figure inner text: (D)"], "seed_role": "figure_inner_text", "seed_confidence": 0.9, "seed_evidence": ["panel label / figure inner text: (D)"], "span_metadata": null, "raw_observation": {"block_id": 8, "page": 12, "raw_label": "figure_title", "text": "(D)", "bbox": [107, 820, 150, 851], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "panel_label", "raw_marker": "(D)", "number": null, "kind": "panel_label", "normalized_text": "(D)"}, "layout_signature": {"width": 43, "width_bucket": 50, "height": 31, "left": 107, "top": 820, "right": 150, "bottom": 851, "x_center": 128.5, "x_center_bucket": 125, "y_center": 835.5, "x_ratio": 0.1079, "y_ratio": 0.5339, "width_ratio": 0.0361, "height_ratio": 0.0198, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "display_zone", "style_family": "legend_like", "style_family_authority": "figure_marker", "reading_band_id": "band_140", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 12, "block_id": 9, "raw_label": "image", "raw_order": null, "bbox": [108, 823, 966, 901], "text": "", "page_width": 1191, "page_height": 1565, "role": "media_asset", "role_confidence": 0.85, "evidence": ["media label: image"], "seed_role": "media_asset", "seed_confidence": 0.85, "seed_evidence": ["media label: image"], "span_metadata": null, "raw_observation": {"block_id": 9, "page": 12, "raw_label": "image", "text": "", "bbox": [108, 823, 966, 901], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "empty", "raw_marker": null, "number": null, "kind": null, "normalized_text": ""}, "layout_signature": {"width": 858, "width_bucket": 850, "height": 78, "left": 108, "top": 823, "right": 966, "bottom": 901, "x_center": 537.0, "x_center_bucket": 525, "y_center": 862.0, "x_ratio": 0.4509, "y_ratio": 0.5508, "width_ratio": 0.7204, "height_ratio": 0.0498, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_138", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.0, "decision": "body", "evidence": []}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"], "asset_family_hint": "figure_like", "asset_family_confidence": 0.7, "asset_family_evidence": ["raw_label:image"]}
+{"paper_id": "2HEUD5P9", "page": 12, "block_id": 10, "raw_label": "figure_title", "raw_order": null, "bbox": [761, 911, 802, 941], "text": "(E)", "page_width": 1191, "page_height": 1565, "role": "figure_inner_text", "role_confidence": 0.9, "evidence": ["panel label / figure inner text: (E)"], "seed_role": "figure_inner_text", "seed_confidence": 0.9, "seed_evidence": ["panel label / figure inner text: (E)"], "span_metadata": null, "raw_observation": {"block_id": 10, "page": 12, "raw_label": "figure_title", "text": "(E)", "bbox": [761, 911, 802, 941], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "panel_label", "raw_marker": "(E)", "number": null, "kind": "panel_label", "normalized_text": "(E)"}, "layout_signature": {"width": 41, "width_bucket": 50, "height": 30, "left": 761, "top": 911, "right": 802, "bottom": 941, "x_center": 781.5, "x_center_bucket": 775, "y_center": 926.0, "x_ratio": 0.6562, "y_ratio": 0.5917, "width_ratio": 0.0344, "height_ratio": 0.0192, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "display_zone", "style_family": "legend_like", "style_family_authority": "figure_marker", "reading_band_id": "band_141", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "hard", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 12, "block_id": 11, "raw_label": "image", "raw_order": null, "bbox": [157, 923, 725, 1177], "text": "", "page_width": 1191, "page_height": 1565, "role": "media_asset", "role_confidence": 0.85, "evidence": ["media label: image"], "seed_role": "media_asset", "seed_confidence": 0.85, "seed_evidence": ["media label: image"], "span_metadata": null, "raw_observation": {"block_id": 11, "page": 12, "raw_label": "image", "text": "", "bbox": [157, 923, 725, 1177], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "empty", "raw_marker": null, "number": null, "kind": null, "normalized_text": ""}, "layout_signature": {"width": 568, "width_bucket": 575, "height": 254, "left": 157, "top": 923, "right": 725, "bottom": 1177, "x_center": 441.0, "x_center_bucket": 450, "y_center": 1050.0, "x_ratio": 0.3703, "y_ratio": 0.6709, "width_ratio": 0.4769, "height_ratio": 0.1623, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_142", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.0, "decision": "body", "evidence": []}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"], "asset_family_hint": "figure_like", "asset_family_confidence": 0.7, "asset_family_evidence": ["raw_label:image"]}
+{"paper_id": "2HEUD5P9", "page": 12, "block_id": 12, "raw_label": "image", "raw_order": null, "bbox": [830, 918, 1028, 1103], "text": "", "page_width": 1191, "page_height": 1565, "role": "media_asset", "role_confidence": 0.85, "evidence": ["media label: image"], "seed_role": "media_asset", "seed_confidence": 0.85, "seed_evidence": ["media label: image"], "span_metadata": null, "raw_observation": {"block_id": 12, "page": 12, "raw_label": "image", "text": "", "bbox": [830, 918, 1028, 1103], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "empty", "raw_marker": null, "number": null, "kind": null, "normalized_text": ""}, "layout_signature": {"width": 198, "width_bucket": 200, "height": 185, "left": 830, "top": 918, "right": 1028, "bottom": 1103, "x_center": 929.0, "x_center_bucket": 925, "y_center": 1010.5, "x_ratio": 0.78, "y_ratio": 0.6457, "width_ratio": 0.1662, "height_ratio": 0.1182, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_142", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"], "asset_family_hint": "figure_like", "asset_family_confidence": 0.7, "asset_family_evidence": ["raw_label:image"]}
+{"paper_id": "2HEUD5P9", "page": 12, "block_id": 13, "raw_label": "image", "raw_order": null, "bbox": [160, 1209, 445, 1394], "text": "", "page_width": 1191, "page_height": 1565, "role": "media_asset", "role_confidence": 0.85, "evidence": ["media label: image"], "seed_role": "media_asset", "seed_confidence": 0.85, "seed_evidence": ["media label: image"], "span_metadata": null, "raw_observation": {"block_id": 13, "page": 12, "raw_label": "image", "text": "", "bbox": [160, 1209, 445, 1394], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "empty", "raw_marker": null, "number": null, "kind": null, "normalized_text": ""}, "layout_signature": {"width": 285, "width_bucket": 275, "height": 185, "left": 160, "top": 1209, "right": 445, "bottom": 1394, "x_center": 302.5, "x_center_bucket": 300, "y_center": 1301.5, "x_ratio": 0.254, "y_ratio": 0.8316, "width_ratio": 0.2393, "height_ratio": 0.1182, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_136", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"], "asset_family_hint": "figure_like", "asset_family_confidence": 0.7, "asset_family_evidence": ["raw_label:image"]}
+{"paper_id": "2HEUD5P9", "page": 12, "block_id": 14, "raw_label": "figure_title", "raw_order": null, "bbox": [754, 1119, 794, 1151], "text": "(F)", "page_width": 1191, "page_height": 1565, "role": "figure_inner_text", "role_confidence": 0.9, "evidence": ["panel label / figure inner text: (F)"], "seed_role": "figure_inner_text", "seed_confidence": 0.9, "seed_evidence": ["panel label / figure inner text: (F)"], "span_metadata": null, "raw_observation": {"block_id": 14, "page": 12, "raw_label": "figure_title", "text": "(F)", "bbox": [754, 1119, 794, 1151], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "panel_label", "raw_marker": "(F)", "number": null, "kind": "panel_label", "normalized_text": "(F)"}, "layout_signature": {"width": 40, "width_bucket": 50, "height": 32, "left": 754, "top": 1119, "right": 794, "bottom": 1151, "x_center": 774.0, "x_center_bucket": 775, "y_center": 1135.0, "x_ratio": 0.6499, "y_ratio": 0.7252, "width_ratio": 0.0336, "height_ratio": 0.0204, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "display_zone", "style_family": "legend_like", "style_family_authority": "figure_marker", "reading_band_id": "band_136", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 12, "block_id": 15, "raw_label": "image", "raw_order": null, "bbox": [458, 1181, 729, 1409], "text": "", "page_width": 1191, "page_height": 1565, "role": "media_asset", "role_confidence": 0.85, "evidence": ["media label: image"], "seed_role": "media_asset", "seed_confidence": 0.85, "seed_evidence": ["media label: image"], "span_metadata": null, "raw_observation": {"block_id": 15, "page": 12, "raw_label": "image", "text": "", "bbox": [458, 1181, 729, 1409], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "empty", "raw_marker": null, "number": null, "kind": null, "normalized_text": ""}, "layout_signature": {"width": 271, "width_bucket": 275, "height": 228, "left": 458, "top": 1181, "right": 729, "bottom": 1409, "x_center": 593.5, "x_center_bucket": 600, "y_center": 1295.0, "x_ratio": 0.4983, "y_ratio": 0.8275, "width_ratio": 0.2275, "height_ratio": 0.1457, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_136", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"], "asset_family_hint": "figure_like", "asset_family_confidence": 0.7, "asset_family_evidence": ["raw_label:image"]}
+{"paper_id": "2HEUD5P9", "page": 12, "block_id": 16, "raw_label": "image", "raw_order": null, "bbox": [804, 1121, 1040, 1265], "text": "", "page_width": 1191, "page_height": 1565, "role": "media_asset", "role_confidence": 0.85, "evidence": ["media label: image"], "seed_role": "media_asset", "seed_confidence": 0.85, "seed_evidence": ["media label: image"], "span_metadata": null, "raw_observation": {"block_id": 16, "page": 12, "raw_label": "image", "text": "", "bbox": [804, 1121, 1040, 1265], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "empty", "raw_marker": null, "number": null, "kind": null, "normalized_text": ""}, "layout_signature": {"width": 236, "width_bucket": 225, "height": 144, "left": 804, "top": 1121, "right": 1040, "bottom": 1265, "x_center": 922.0, "x_center_bucket": 925, "y_center": 1193.0, "x_ratio": 0.7741, "y_ratio": 0.7623, "width_ratio": 0.1982, "height_ratio": 0.092, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_136", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"], "asset_family_hint": "figure_like", "asset_family_confidence": 0.7, "asset_family_evidence": ["raw_label:image"]}
+{"paper_id": "2HEUD5P9", "page": 12, "block_id": 17, "raw_label": "image", "raw_order": null, "bbox": [803, 1276, 1041, 1420], "text": "", "page_width": 1191, "page_height": 1565, "role": "media_asset", "role_confidence": 0.85, "evidence": ["media label: image"], "seed_role": "media_asset", "seed_confidence": 0.85, "seed_evidence": ["media label: image"], "span_metadata": null, "raw_observation": {"block_id": 17, "page": 12, "raw_label": "image", "text": "", "bbox": [803, 1276, 1041, 1420], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "empty", "raw_marker": null, "number": null, "kind": null, "normalized_text": ""}, "layout_signature": {"width": 238, "width_bucket": 250, "height": 144, "left": 803, "top": 1276, "right": 1041, "bottom": 1420, "x_center": 922.0, "x_center_bucket": 925, "y_center": 1348.0, "x_ratio": 0.7741, "y_ratio": 0.8613, "width_ratio": 0.1998, "height_ratio": 0.092, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_136", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"], "asset_family_hint": "figure_like", "asset_family_confidence": 0.7, "asset_family_evidence": ["raw_label:image"]}
+{"paper_id": "2HEUD5P9", "page": 12, "block_id": 18, "raw_label": "footer", "raw_order": null, "bbox": [94, 1486, 283, 1505], "text": "Small Methods 2024, 8, 2301283", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["footer label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["footer label"], "span_metadata": [{"size": 6.973800182342529, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 18, "page": 12, "raw_label": "footer", "text": "Small Methods 2024, 8, 2301283", "bbox": [94, 1486, 283, 1505], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "Small Methods 2024, 8, 2301283"}, "layout_signature": {"width": 189, "width_bucket": 200, "height": 19, "left": 94, "top": 1486, "right": 283, "bottom": 1505, "x_center": 188.5, "x_center_bucket": 200, "y_center": 1495.5, "x_ratio": 0.1583, "y_ratio": 0.9556, "width_ratio": 0.1587, "height_ratio": 0.0121, "line_count": 1}, "span_signature": {"font_size": 6.97, "font_size_median": 6.97, "font_size_bucket": 7.0, "font_family_norm": "ScalaSansPro-Italic", "bold": true, "italic": true, "span_count": 5}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_136", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 12, "block_id": 19, "raw_label": "footer", "raw_order": null, "bbox": [521, 1484, 663, 1508], "text": "2301283 (12 of 27)", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["footer label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["footer label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaSansPro-Bold", "flags": 20, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 19, "page": 12, "raw_label": "footer", "text": "2301283 (12 of 27)", "bbox": [521, 1484, 663, 1508], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_dot", "raw_marker": "2301283", "number": 2301283, "kind": "reference", "normalized_text": "2301283 (12 of 27)"}, "layout_signature": {"width": 142, "width_bucket": 150, "height": 24, "left": 521, "top": 1484, "right": 663, "bottom": 1508, "x_center": 592.0, "x_center_bucket": 600, "y_center": 1496.0, "x_ratio": 0.4971, "y_ratio": 0.9559, "width_ratio": 0.1192, "height_ratio": 0.0153, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaSansPro-Bold", "bold": true, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "reference_like", "style_family_authority": "reference_family_anchor", "reading_band_id": "band_136", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 12, "block_id": 20, "raw_label": "footer", "raw_order": null, "bbox": [931, 1486, 1090, 1506], "text": "© 2024 Wiley-VCH GmbH", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["footer label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["footer label"], "span_metadata": [{"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 20, "page": 12, "raw_label": "footer", "text": "© 2024 Wiley-VCH GmbH", "bbox": [931, 1486, 1090, 1506], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "© 2024 Wiley-VCH GmbH"}, "layout_signature": {"width": 159, "width_bucket": 150, "height": 20, "left": 931, "top": 1486, "right": 1090, "bottom": 1506, "x_center": 1010.5, "x_center_bucket": 1000, "y_center": 1496.0, "x_ratio": 0.8484, "y_ratio": 0.9559, "width_ratio": 0.1335, "height_ratio": 0.0128, "line_count": 1}, "span_signature": {"font_size": 6.97, "font_size_median": 6.97, "font_size_bucket": 7.0, "font_family_norm": "ScalaSansPro-Regular", "bold": false, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_136", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 12, "block_id": 21, "raw_label": "aside_text", "raw_order": null, "bbox": [1154, 30, 1171, 1535], "text": "23699608, 2024, 8, Downloaded from https://onlinelibrary.wiley.com/doi/10.1002/smkt.202301283 by Shandong University Library, Wiley Online Library on [18/02/2026]. See the Terms and Conditions (https://onlinelibrary.wiley.com/terms-and-conditions) on Wiley Online Library for rules of use; OA articles are governed by the applicable Creative Commons License", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.95, "evidence": ["margin-band narrow/tall geometry; treated as noise"], "seed_role": "noise", "seed_confidence": 0.95, "seed_evidence": ["margin-band narrow/tall geometry; treated as noise"], "span_metadata": [{"size": 5.03000020980835, "font": "Times-Roman", "flags": 4, "color": 0, "dir": [0.0, 1.0], "wmode": 0}], "raw_observation": {"block_id": 21, "page": 12, "raw_label": "aside_text", "text": "23699608, 2024, 8, Downloaded from https://onlinelibrary.wiley.com/doi/10.1002/smkt.202301283 by Shandong University Library, Wiley Online Library on [18/02/2026]. See the Terms and Conditions (https://onlinelibrary.wiley.com/terms-and-conditions) on Wiley Online Library for rules of use; OA articles are governed by the applicable Creative Commons License", "bbox": [1154, 30, 1171, 1535], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "23699608, 2024, 8, Downloaded from https://onlinelibrary.wiley.com/doi/10.1002/smkt.202301283 by Shandong University Library, Wiley Online Library on [18/02/2026]. See the Terms and Conditions (https://onlinelibrary.wiley.com/terms-and-conditions) on Wiley Online Library for rules of use; OA articles are governed by the applicable Creative Commons License"}, "layout_signature": {"width": 17, "width_bucket": 25, "height": 1505, "left": 1154, "top": 30, "right": 1171, "bottom": 1535, "x_center": 1162.5, "x_center_bucket": 1150, "y_center": 782.5, "x_ratio": 0.9761, "y_ratio": 0.5, "width_ratio": 0.0143, "height_ratio": 0.9617, "line_count": 1}, "span_signature": {"font_size": 5.03, "font_size_median": 5.03, "font_size_bucket": 5.0, "font_family_norm": "Times-Roman", "bold": false, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_family_anchor", "reading_band_id": "band_133", "display_cluster_candidate_id": "disp_26_0", "layout_region": "display_zone", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 13, "block_id": 0, "raw_label": "header", "raw_order": null, "bbox": [98, 46, 345, 117], "text": "ADVANCED\nSCIENCE NEWS\nwww.advancedsciencenews.com", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["header label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["header label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaSansPro-Bold", "flags": 20, "color": 255, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 0, "page": 13, "raw_label": "header", "text": "ADVANCED\nSCIENCE NEWS\nwww.advancedsciencenews.com", "bbox": [98, 46, 345, 117], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "ADVANCED\nSCIENCE NEWS\nwww.advancedsciencenews.com"}, "layout_signature": {"width": 247, "width_bucket": 250, "height": 71, "left": 98, "top": 46, "right": 345, "bottom": 117, "x_center": 221.5, "x_center_bucket": 225, "y_center": 81.5, "x_ratio": 0.186, "y_ratio": 0.0521, "width_ratio": 0.2074, "height_ratio": 0.0454, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaSansPro-Bold", "bold": true, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 13, "block_id": 1, "raw_label": "header", "raw_order": null, "bbox": [1003, 36, 1096, 95], "text": "small methods", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["header label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["header label"], "span_metadata": null, "raw_observation": {"block_id": 1, "page": 13, "raw_label": "header", "text": "small methods", "bbox": [1003, 36, 1096, 95], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "short_fragment", "raw_marker": "small methods", "number": null, "kind": "short_fragment", "normalized_text": "small methods"}, "layout_signature": {"width": 93, "width_bucket": 100, "height": 59, "left": 1003, "top": 36, "right": 1096, "bottom": 95, "x_center": 1049.5, "x_center_bucket": 1050, "y_center": 65.5, "x_ratio": 0.8812, "y_ratio": 0.0419, "width_ratio": 0.0781, "height_ratio": 0.0377, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": true, "_container_bbox": [1005.7522789906125, 37.836628863963085, 1084.0337389451988, 91.04600210547972], "_container_text": "small methods", "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_142", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.6, "decision": "structured_insert_candidate", "evidence": ["visual_container", "narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 13, "block_id": 2, "raw_label": "header", "raw_order": null, "bbox": [902, 98, 1096, 116], "text": "www.small-methods.com", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["header label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["header label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaSansPro-Bold", "flags": 20, "color": 255, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 2, "page": 13, "raw_label": "header", "text": "www.small-methods.com", "bbox": [902, 98, 1096, 116], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "www.small-methods.com"}, "layout_signature": {"width": 194, "width_bucket": 200, "height": 18, "left": 902, "top": 98, "right": 1096, "bottom": 116, "x_center": 999.0, "x_center_bucket": 1000, "y_center": 107.0, "x_ratio": 0.8388, "y_ratio": 0.0684, "width_ratio": 0.1629, "height_ratio": 0.0115, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaSansPro-Bold", "bold": true, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_142", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 13, "block_id": 3, "raw_label": "text", "raw_order": 1, "bbox": [95, 149, 586, 192], "text": "osteosarcoma destruction, anti-bacteria, and bone defect regeneration abilities (Figure 5I–L). $ ^{[123]} $", "page_width": 1191, "page_height": 1565, "role": "body_paragraph", "role_confidence": 0.6, "evidence": ["default body_paragraph for text label"], "seed_role": "body_paragraph", "seed_confidence": 0.6, "seed_evidence": ["default body_paragraph for text label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 3, "page": 13, "raw_label": "text", "text": "osteosarcoma destruction, anti-bacteria, and bone defect regeneration abilities (Figure 5I–L). $ ^{[123]} $", "bbox": [95, 149, 586, 192], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "osteosarcoma destruction, anti-bacteria, and bone defect regeneration abilities (Figure 5I–L). $ ^{[123]} $"}, "layout_signature": {"width": 491, "width_bucket": 500, "height": 43, "left": 95, "top": 149, "right": 586, "bottom": 192, "x_center": 340.5, "x_center_bucket": 350, "y_center": 170.5, "x_ratio": 0.2859, "y_ratio": 0.1089, "width_ratio": 0.4123, "height_ratio": 0.0275, "line_count": 1}, "span_signature": {"font_size": 8.49, "font_size_median": 8.97, "font_size_bucket": 8.5, "font_family_norm": "ScalaPro-Regular", "bold": false, "italic": true, "span_count": 19}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_139", "display_cluster_candidate_id": "disp_27_0", "layout_region": "display_zone", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 13, "block_id": 4, "raw_label": "text", "raw_order": 2, "bbox": [96, 193, 588, 260], "text": "The preparation method of LDH has a great influence on its properties. For example, different preparation methods can obtain different layered structures, which can affect its physical and chemical properties. Common preparation methods include coprecipitation, hydrothermal synthesis, ion exchange, etc. In addition, the preparation method of LDH can also affect its crystal structure, specific surface area, pore size, ion exchange capacity, and other properties.", "page_width": 1191, "page_height": 1565, "role": "body_paragraph", "role_confidence": 0.6, "evidence": ["default body_paragraph for text label"], "seed_role": "body_paragraph", "seed_confidence": 0.6, "seed_evidence": ["default body_paragraph for text label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 4, "page": 13, "raw_label": "text", "text": "The preparation method of LDH has a great influence on its properties. For example, different preparation methods can obtain different layered structures, which can affect its physical and chemical properties. Common preparation methods include coprecipitation, hydrothermal synthesis, ion exchange, etc. In addition, the preparation method of LDH can also affect its crystal structure, specific surface area, pore size, ion exchange capacity, and other properties.", "bbox": [96, 193, 588, 260], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "The preparation method of LDH has a great influence on its properties. For example, different preparation methods can obtain different layered structures, which can affect its physical and chemical properties. Common preparation methods include coprecipitation, hydrothermal synthesis, ion exchange, etc. In addition, the preparation method of LDH can also affect its crystal structure, specific surface area, pore size, ion exchange capacity, and other properties."}, "layout_signature": {"width": 492, "width_bucket": 500, "height": 67, "left": 96, "top": 193, "right": 588, "bottom": 260, "x_center": 342.0, "x_center_bucket": 350, "y_center": 226.5, "x_ratio": 0.2872, "y_ratio": 0.1447, "width_ratio": 0.4131, "height_ratio": 0.0428, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaPro-Regular", "bold": false, "italic": true, "span_count": 37}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_140", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 13, "block_id": 5, "raw_label": "text", "raw_order": 3, "bbox": [605, 149, 1098, 260], "text": "", "page_width": 1191, "page_height": 1565, "role": "ocr_text_missing", "role_confidence": 0.8, "evidence": ["ocr detected text region (raw_label=text) but no text extracted; no pdf backfill available"], "seed_role": "ocr_text_missing", "seed_confidence": 0.8, "seed_evidence": ["ocr detected text region (raw_label=text) but no text extracted; no pdf backfill available"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 5, "page": 13, "raw_label": "text", "text": "", "bbox": [605, 149, 1098, 260], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "empty", "raw_marker": null, "number": null, "kind": null, "normalized_text": ""}, "layout_signature": {"width": 493, "width_bucket": 500, "height": 111, "left": 605, "top": 149, "right": 1098, "bottom": 260, "x_center": 851.5, "x_center_bucket": 850, "y_center": 204.5, "x_ratio": 0.7149, "y_ratio": 0.1307, "width_ratio": 0.4139, "height_ratio": 0.0709, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaPro-Regular", "bold": false, "italic": true, "span_count": 19}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": "pdf_text_layer_fallback_rejected", "_ocr_raw_status": "missing_text_rejected", "_ocr_raw_error_type": "backfill_overlaps_existing_text_block", "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "_needs_pdf_fallback": true, "reading_band_id": "band_139", "display_cluster_candidate_id": "disp_27_0", "layout_region": "display_zone", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 13, "block_id": 6, "raw_label": "text", "raw_order": 4, "bbox": [96, 319, 1099, 417], "text": "Figure 4. A) Scheme showing MgGA MOF and PLGA/Mg-GA MOF scaffold preparation. B) ALP staining of hBMSCs in the extracts. C) ARS staining of hBMSCs in the extracts. $ ^{[112]} $ Copyright 2022, Elsevier. D) Schematic of fabrication of the PCL/Col/ZIF-8 composite membrane for guided bone regeneration. The asymmetric double-layer membrane was fabricated using a polymer blend of PCL and Col (1:1 and 1:1.5) based on the monolayer by electrospinning. E) SEM image of PCL/Col/ZIF-8 composite. F) The PCL/Col/ZIF-8 composite membrane was implanted into a rat calvarial defect to evaluate its ability to enhance bone regeneration and blood vessel formation. $ ^{[113]} $ Copyright 2021, Wiley-VCH.", "page_width": 1191, "page_height": 1565, "role": "body_paragraph", "role_confidence": 0.9, "evidence": ["figure caption candidate (body narrative): Figure 4. A) Scheme showing MgGA MOF and PLGA/Mg-GA MOF scaf"], "seed_role": "figure_caption_candidate", "seed_confidence": 0.9, "seed_evidence": ["figure caption candidate (body narrative): Figure 4. A) Scheme showing MgGA MOF and PLGA/Mg-GA MOF scaf"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaSansPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaSansPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaSansPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaSansPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaSansPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaSansPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 6, "page": 13, "raw_label": "text", "text": "Figure 4. A) Scheme showing MgGA MOF and PLGA/Mg-GA MOF scaffold preparation. B) ALP staining of hBMSCs in the extracts. C) ARS staining of hBMSCs in the extracts. $ ^{[112]} $ Copyright 2022, Elsevier. D) Schematic of fabrication of the PCL/Col/ZIF-8 composite membrane for guided bone regeneration. The asymmetric double-layer membrane was fabricated using a polymer blend of PCL and Col (1:1 and 1:1.5) based on the monolayer by electrospinning. E) SEM image of PCL/Col/ZIF-8 composite. F) The PCL/Col/ZIF-8 composite membrane was implanted into a rat calvarial defect to evaluate its ability to enhance bone regeneration and blood vessel formation. $ ^{[113]} $ Copyright 2021, Wiley-VCH.", "bbox": [96, 319, 1099, 417], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "figure_number", "raw_marker": "Figure 4", "number": 4, "kind": "figure", "normalized_text": "Figure 4. A) Scheme showing MgGA MOF and PLGA/Mg-GA MOF scaffold preparation. B) ALP staining of hBMSCs in the extracts. C) ARS staining of hBMSCs in the extracts. $ ^{[112]} $ Copyright 2022, Elsevier. D) Schematic of fabrication of the PCL/Col/ZIF-8 composite membrane for guided bone regeneration. The asymmetric double-layer membrane was fabricated using a polymer blend of PCL and Col (1:1 and 1:1.5) based on the monolayer by electrospinning. E) SEM image of PCL/Col/ZIF-8 composite. F) The PCL/Col/ZIF-8 composite membrane was implanted into a rat calvarial defect to evaluate its ability to enhance bone regeneration and blood vessel formation. $ ^{[113]} $ Copyright 2021, Wiley-VCH."}, "layout_signature": {"width": 1003, "width_bucket": 1000, "height": 98, "left": 96, "top": 319, "right": 1099, "bottom": 417, "x_center": 597.5, "x_center_bucket": 600, "y_center": 368.0, "x_ratio": 0.5017, "y_ratio": 0.2351, "width_ratio": 0.8421, "height_ratio": 0.0626, "line_count": 1}, "span_signature": {"font_size": 7.75, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Bold", "bold": true, "italic": true, "span_count": 55}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "display_zone", "style_family": "legend_like", "style_family_authority": "figure_marker", "reading_band_id": "band_140", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.0, "decision": "body", "evidence": []}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"], "_rejected_legend": {"reason": "demoted_body_paragraph", "role": "body_paragraph", "seed_role": "figure_caption_candidate"}}
+{"paper_id": "2HEUD5P9", "page": 13, "block_id": 7, "raw_label": "figure_title", "raw_order": null, "bbox": [107, 432, 140, 456], "text": "(A)", "page_width": 1191, "page_height": 1565, "role": "figure_inner_text", "role_confidence": 0.9, "evidence": ["panel label / figure inner text: (A)"], "seed_role": "figure_inner_text", "seed_confidence": 0.9, "seed_evidence": ["panel label / figure inner text: (A)"], "span_metadata": null, "raw_observation": {"block_id": 7, "page": 13, "raw_label": "figure_title", "text": "(A)", "bbox": [107, 432, 140, 456], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "panel_label", "raw_marker": "(A)", "number": null, "kind": "panel_label", "normalized_text": "(A)"}, "layout_signature": {"width": 33, "width_bucket": 25, "height": 24, "left": 107, "top": 432, "right": 140, "bottom": 456, "x_center": 123.5, "x_center_bucket": 125, "y_center": 444.0, "x_ratio": 0.1037, "y_ratio": 0.2837, "width_ratio": 0.0277, "height_ratio": 0.0153, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "display_zone", "style_family": "legend_like", "style_family_authority": "figure_marker", "reading_band_id": "band_139", "display_cluster_candidate_id": "disp_27_0", "layout_region": "display_zone", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 13, "block_id": 8, "raw_label": "image", "raw_order": null, "bbox": [133, 439, 516, 613], "text": "", "page_width": 1191, "page_height": 1565, "role": "figure_asset", "role_confidence": 0.85, "evidence": ["media label: image"], "seed_role": "media_asset", "seed_confidence": 0.85, "seed_evidence": ["media label: image"], "span_metadata": null, "raw_observation": {"block_id": 8, "page": 13, "raw_label": "image", "text": "", "bbox": [133, 439, 516, 613], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "empty", "raw_marker": null, "number": null, "kind": null, "normalized_text": ""}, "layout_signature": {"width": 383, "width_bucket": 375, "height": 174, "left": 133, "top": 439, "right": 516, "bottom": 613, "x_center": 324.5, "x_center_bucket": 325, "y_center": 526.0, "x_ratio": 0.2725, "y_ratio": 0.3361, "width_ratio": 0.3216, "height_ratio": 0.1112, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_140", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"], "asset_family_hint": "figure_like", "asset_family_confidence": 0.7, "asset_family_evidence": ["raw_label:image"]}
+{"paper_id": "2HEUD5P9", "page": 13, "block_id": 9, "raw_label": "figure_title", "raw_order": null, "bbox": [104, 599, 136, 622], "text": "(B)", "page_width": 1191, "page_height": 1565, "role": "figure_inner_text", "role_confidence": 0.9, "evidence": ["panel label / figure inner text: (B)"], "seed_role": "figure_inner_text", "seed_confidence": 0.9, "seed_evidence": ["panel label / figure inner text: (B)"], "span_metadata": null, "raw_observation": {"block_id": 9, "page": 13, "raw_label": "figure_title", "text": "(B)", "bbox": [104, 599, 136, 622], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "panel_label", "raw_marker": "(B)", "number": null, "kind": "panel_label", "normalized_text": "(B)"}, "layout_signature": {"width": 32, "width_bucket": 25, "height": 23, "left": 104, "top": 599, "right": 136, "bottom": 622, "x_center": 120.0, "x_center_bucket": 125, "y_center": 610.5, "x_ratio": 0.1008, "y_ratio": 0.3901, "width_ratio": 0.0269, "height_ratio": 0.0147, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "display_zone", "style_family": "legend_like", "style_family_authority": "figure_marker", "reading_band_id": "band_138", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 13, "block_id": 10, "raw_label": "figure_title", "raw_order": null, "bbox": [521, 428, 552, 452], "text": "(c)", "page_width": 1191, "page_height": 1565, "role": "figure_inner_text", "role_confidence": 0.9, "evidence": ["panel label / figure inner text: (c)"], "seed_role": "figure_inner_text", "seed_confidence": 0.9, "seed_evidence": ["panel label / figure inner text: (c)"], "span_metadata": null, "raw_observation": {"block_id": 10, "page": 13, "raw_label": "figure_title", "text": "(c)", "bbox": [521, 428, 552, 452], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "panel_label", "raw_marker": "(c)", "number": null, "kind": "panel_label", "normalized_text": "(c)"}, "layout_signature": {"width": 31, "width_bucket": 25, "height": 24, "left": 521, "top": 428, "right": 552, "bottom": 452, "x_center": 536.5, "x_center_bucket": 525, "y_center": 440.0, "x_ratio": 0.4505, "y_ratio": 0.2812, "width_ratio": 0.026, "height_ratio": 0.0153, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "display_zone", "style_family": "legend_like", "style_family_authority": "figure_marker", "reading_band_id": "band_141", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "hard", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 13, "block_id": 11, "raw_label": "image", "raw_order": null, "bbox": [534, 435, 785, 582], "text": "", "page_width": 1191, "page_height": 1565, "role": "figure_asset", "role_confidence": 0.85, "evidence": ["media label: image"], "seed_role": "media_asset", "seed_confidence": 0.85, "seed_evidence": ["media label: image"], "span_metadata": null, "raw_observation": {"block_id": 11, "page": 13, "raw_label": "image", "text": "", "bbox": [534, 435, 785, 582], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "empty", "raw_marker": null, "number": null, "kind": null, "normalized_text": ""}, "layout_signature": {"width": 251, "width_bucket": 250, "height": 147, "left": 534, "top": 435, "right": 785, "bottom": 582, "x_center": 659.5, "x_center_bucket": 650, "y_center": 508.5, "x_ratio": 0.5537, "y_ratio": 0.3249, "width_ratio": 0.2107, "height_ratio": 0.0939, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_142", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"], "asset_family_hint": "figure_like", "asset_family_confidence": 0.7, "asset_family_evidence": ["raw_label:image"]}
+{"paper_id": "2HEUD5P9", "page": 13, "block_id": 12, "raw_label": "figure_title", "raw_order": null, "bbox": [813, 433, 845, 457], "text": "(E)", "page_width": 1191, "page_height": 1565, "role": "figure_inner_text", "role_confidence": 0.9, "evidence": ["panel label / figure inner text: (E)"], "seed_role": "figure_inner_text", "seed_confidence": 0.9, "seed_evidence": ["panel label / figure inner text: (E)"], "span_metadata": null, "raw_observation": {"block_id": 12, "page": 13, "raw_label": "figure_title", "text": "(E)", "bbox": [813, 433, 845, 457], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "panel_label", "raw_marker": "(E)", "number": null, "kind": "panel_label", "normalized_text": "(E)"}, "layout_signature": {"width": 32, "width_bucket": 25, "height": 24, "left": 813, "top": 433, "right": 845, "bottom": 457, "x_center": 829.0, "x_center_bucket": 825, "y_center": 445.0, "x_ratio": 0.6961, "y_ratio": 0.2843, "width_ratio": 0.0269, "height_ratio": 0.0153, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "display_zone", "style_family": "legend_like", "style_family_authority": "figure_marker", "reading_band_id": "band_142", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 13, "block_id": 13, "raw_label": "figure_title", "raw_order": null, "bbox": [901, 429, 929, 444], "text": "4 W", "page_width": 1191, "page_height": 1565, "role": "figure_caption_candidate", "role_confidence": 0.85, "evidence": ["figure_title label: 4 W"], "seed_role": "figure_caption", "seed_confidence": 0.85, "seed_evidence": ["figure_title label: 4 W"], "span_metadata": null, "raw_observation": {"block_id": 13, "page": 13, "raw_label": "figure_title", "text": "4 W", "bbox": [901, 429, 929, 444], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_dot", "raw_marker": "4", "number": 4, "kind": "reference", "normalized_text": "4 W"}, "layout_signature": {"width": 28, "width_bucket": 25, "height": 15, "left": 901, "top": 429, "right": 929, "bottom": 444, "x_center": 915.0, "x_center_bucket": 925, "y_center": 436.5, "x_ratio": 0.7683, "y_ratio": 0.2789, "width_ratio": 0.0235, "height_ratio": 0.0096, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_136", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "CANDIDATE", "role_source": "pre_object_figure_caption_candidate", "role_evidence": ["figure caption seed requires figure inventory verification"], "role_candidate": "figure_caption", "caption_score": {"score": 0.0, "decision": "rejected", "evidence": []}}
+{"paper_id": "2HEUD5P9", "page": 13, "block_id": 14, "raw_label": "image", "raw_order": null, "bbox": [849, 442, 966, 545], "text": "", "page_width": 1191, "page_height": 1565, "role": "figure_asset", "role_confidence": 0.85, "evidence": ["media label: image"], "seed_role": "media_asset", "seed_confidence": 0.85, "seed_evidence": ["media label: image"], "span_metadata": null, "raw_observation": {"block_id": 14, "page": 13, "raw_label": "image", "text": "", "bbox": [849, 442, 966, 545], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "empty", "raw_marker": null, "number": null, "kind": null, "normalized_text": ""}, "layout_signature": {"width": 117, "width_bucket": 125, "height": 103, "left": 849, "top": 442, "right": 966, "bottom": 545, "x_center": 907.5, "x_center_bucket": 900, "y_center": 493.5, "x_ratio": 0.762, "y_ratio": 0.3153, "width_ratio": 0.0982, "height_ratio": 0.0658, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_136", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"], "asset_family_hint": "figure_like", "asset_family_confidence": 0.7, "asset_family_evidence": ["raw_label:image"]}
+{"paper_id": "2HEUD5P9", "page": 13, "block_id": 15, "raw_label": "figure_title", "raw_order": null, "bbox": [1015, 429, 1045, 444], "text": "8 W", "page_width": 1191, "page_height": 1565, "role": "figure_caption_candidate", "role_confidence": 0.85, "evidence": ["figure_title label: 8 W"], "seed_role": "figure_caption", "seed_confidence": 0.85, "seed_evidence": ["figure_title label: 8 W"], "span_metadata": null, "raw_observation": {"block_id": 15, "page": 13, "raw_label": "figure_title", "text": "8 W", "bbox": [1015, 429, 1045, 444], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_dot", "raw_marker": "8", "number": 8, "kind": "reference", "normalized_text": "8 W"}, "layout_signature": {"width": 30, "width_bucket": 25, "height": 15, "left": 1015, "top": 429, "right": 1045, "bottom": 444, "x_center": 1030.0, "x_center_bucket": 1025, "y_center": 436.5, "x_ratio": 0.8648, "y_ratio": 0.2789, "width_ratio": 0.0252, "height_ratio": 0.0096, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_136", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "CANDIDATE", "role_source": "pre_object_figure_caption_candidate", "role_evidence": ["figure caption seed requires figure inventory verification"], "role_candidate": "figure_caption", "caption_score": {"score": 0.0, "decision": "rejected", "evidence": []}}
+{"paper_id": "2HEUD5P9", "page": 13, "block_id": 16, "raw_label": "figure_title", "raw_order": null, "bbox": [526, 598, 556, 621], "text": "(D)", "page_width": 1191, "page_height": 1565, "role": "figure_inner_text", "role_confidence": 0.9, "evidence": ["panel label / figure inner text: (D)"], "seed_role": "figure_inner_text", "seed_confidence": 0.9, "seed_evidence": ["panel label / figure inner text: (D)"], "span_metadata": null, "raw_observation": {"block_id": 16, "page": 13, "raw_label": "figure_title", "text": "(D)", "bbox": [526, 598, 556, 621], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "panel_label", "raw_marker": "(D)", "number": null, "kind": "panel_label", "normalized_text": "(D)"}, "layout_signature": {"width": 30, "width_bucket": 25, "height": 23, "left": 526, "top": 598, "right": 556, "bottom": 621, "x_center": 541.0, "x_center_bucket": 550, "y_center": 609.5, "x_ratio": 0.4542, "y_ratio": 0.3895, "width_ratio": 0.0252, "height_ratio": 0.0147, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "display_zone", "style_family": "legend_like", "style_family_authority": "figure_marker", "reading_band_id": "band_136", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 13, "block_id": 17, "raw_label": "image", "raw_order": null, "bbox": [970, 434, 1087, 545], "text": "", "page_width": 1191, "page_height": 1565, "role": "figure_asset", "role_confidence": 0.85, "evidence": ["media label: image"], "seed_role": "media_asset", "seed_confidence": 0.85, "seed_evidence": ["media label: image"], "span_metadata": null, "raw_observation": {"block_id": 17, "page": 13, "raw_label": "image", "text": "", "bbox": [970, 434, 1087, 545], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "empty", "raw_marker": null, "number": null, "kind": null, "normalized_text": ""}, "layout_signature": {"width": 117, "width_bucket": 125, "height": 111, "left": 970, "top": 434, "right": 1087, "bottom": 545, "x_center": 1028.5, "x_center_bucket": 1025, "y_center": 489.5, "x_ratio": 0.8636, "y_ratio": 0.3128, "width_ratio": 0.0982, "height_ratio": 0.0709, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_136", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"], "asset_family_hint": "figure_like", "asset_family_confidence": 0.7, "asset_family_evidence": ["raw_label:image"]}
+{"paper_id": "2HEUD5P9", "page": 13, "block_id": 18, "raw_label": "image", "raw_order": null, "bbox": [113, 622, 253, 786], "text": "", "page_width": 1191, "page_height": 1565, "role": "figure_asset", "role_confidence": 0.85, "evidence": ["media label: image"], "seed_role": "media_asset", "seed_confidence": 0.85, "seed_evidence": ["media label: image"], "span_metadata": null, "raw_observation": {"block_id": 18, "page": 13, "raw_label": "image", "text": "", "bbox": [113, 622, 253, 786], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "empty", "raw_marker": null, "number": null, "kind": null, "normalized_text": ""}, "layout_signature": {"width": 140, "width_bucket": 150, "height": 164, "left": 113, "top": 622, "right": 253, "bottom": 786, "x_center": 183.0, "x_center_bucket": 175, "y_center": 704.0, "x_ratio": 0.1537, "y_ratio": 0.4498, "width_ratio": 0.1175, "height_ratio": 0.1048, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_136", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"], "asset_family_hint": "figure_like", "asset_family_confidence": 0.7, "asset_family_evidence": ["raw_label:image"]}
+{"paper_id": "2HEUD5P9", "page": 13, "block_id": 19, "raw_label": "image", "raw_order": null, "bbox": [256, 624, 391, 771], "text": "", "page_width": 1191, "page_height": 1565, "role": "figure_asset", "role_confidence": 0.85, "evidence": ["media label: image"], "seed_role": "media_asset", "seed_confidence": 0.85, "seed_evidence": ["media label: image"], "span_metadata": null, "raw_observation": {"block_id": 19, "page": 13, "raw_label": "image", "text": "", "bbox": [256, 624, 391, 771], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "empty", "raw_marker": null, "number": null, "kind": null, "normalized_text": ""}, "layout_signature": {"width": 135, "width_bucket": 125, "height": 147, "left": 256, "top": 624, "right": 391, "bottom": 771, "x_center": 323.5, "x_center_bucket": 325, "y_center": 697.5, "x_ratio": 0.2716, "y_ratio": 0.4457, "width_ratio": 0.1134, "height_ratio": 0.0939, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_136", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"], "asset_family_hint": "figure_like", "asset_family_confidence": 0.7, "asset_family_evidence": ["raw_label:image"]}
+{"paper_id": "2HEUD5P9", "page": 13, "block_id": 20, "raw_label": "image", "raw_order": null, "bbox": [394, 625, 528, 780], "text": "", "page_width": 1191, "page_height": 1565, "role": "figure_asset", "role_confidence": 0.85, "evidence": ["media label: image"], "seed_role": "media_asset", "seed_confidence": 0.85, "seed_evidence": ["media label: image"], "span_metadata": null, "raw_observation": {"block_id": 20, "page": 13, "raw_label": "image", "text": "", "bbox": [394, 625, 528, 780], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "empty", "raw_marker": null, "number": null, "kind": null, "normalized_text": ""}, "layout_signature": {"width": 134, "width_bucket": 125, "height": 155, "left": 394, "top": 625, "right": 528, "bottom": 780, "x_center": 461.0, "x_center_bucket": 450, "y_center": 702.5, "x_ratio": 0.3871, "y_ratio": 0.4489, "width_ratio": 0.1125, "height_ratio": 0.099, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_136", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"], "asset_family_hint": "figure_like", "asset_family_confidence": 0.7, "asset_family_evidence": ["raw_label:image"]}
+{"paper_id": "2HEUD5P9", "page": 13, "block_id": 21, "raw_label": "image", "raw_order": null, "bbox": [533, 601, 785, 749], "text": "", "page_width": 1191, "page_height": 1565, "role": "figure_asset", "role_confidence": 0.85, "evidence": ["media label: image"], "seed_role": "media_asset", "seed_confidence": 0.85, "seed_evidence": ["media label: image"], "span_metadata": null, "raw_observation": {"block_id": 21, "page": 13, "raw_label": "image", "text": "", "bbox": [533, 601, 785, 749], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "empty", "raw_marker": null, "number": null, "kind": null, "normalized_text": ""}, "layout_signature": {"width": 252, "width_bucket": 250, "height": 148, "left": 533, "top": 601, "right": 785, "bottom": 749, "x_center": 659.0, "x_center_bucket": 650, "y_center": 675.0, "x_ratio": 0.5533, "y_ratio": 0.4313, "width_ratio": 0.2116, "height_ratio": 0.0946, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_133", "display_cluster_candidate_id": "disp_26_0", "layout_region": "display_zone", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"], "asset_family_hint": "figure_like", "asset_family_confidence": 0.7, "asset_family_evidence": ["raw_label:image"]}
+{"paper_id": "2HEUD5P9", "page": 13, "block_id": 22, "raw_label": "image", "raw_order": null, "bbox": [850, 548, 967, 648], "text": "", "page_width": 1191, "page_height": 1565, "role": "figure_asset", "role_confidence": 0.85, "evidence": ["media label: image"], "seed_role": "media_asset", "seed_confidence": 0.85, "seed_evidence": ["media label: image"], "span_metadata": null, "raw_observation": {"block_id": 22, "page": 13, "raw_label": "image", "text": "", "bbox": [850, 548, 967, 648], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "empty", "raw_marker": null, "number": null, "kind": null, "normalized_text": ""}, "layout_signature": {"width": 117, "width_bucket": 125, "height": 100, "left": 850, "top": 548, "right": 967, "bottom": 648, "x_center": 908.5, "x_center_bucket": 900, "y_center": 598.0, "x_ratio": 0.7628, "y_ratio": 0.3821, "width_ratio": 0.0982, "height_ratio": 0.0639, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_134", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"], "asset_family_hint": "figure_like", "asset_family_confidence": 0.7, "asset_family_evidence": ["raw_label:image"]}
+{"paper_id": "2HEUD5P9", "page": 13, "block_id": 23, "raw_label": "image", "raw_order": null, "bbox": [971, 549, 1086, 647], "text": "", "page_width": 1191, "page_height": 1565, "role": "figure_asset", "role_confidence": 0.85, "evidence": ["media label: image"], "seed_role": "media_asset", "seed_confidence": 0.85, "seed_evidence": ["media label: image"], "span_metadata": null, "raw_observation": {"block_id": 23, "page": 13, "raw_label": "image", "text": "", "bbox": [971, 549, 1086, 647], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "empty", "raw_marker": null, "number": null, "kind": null, "normalized_text": ""}, "layout_signature": {"width": 115, "width_bucket": 125, "height": 98, "left": 971, "top": 549, "right": 1086, "bottom": 647, "x_center": 1028.5, "x_center_bucket": 1025, "y_center": 598.0, "x_ratio": 0.8636, "y_ratio": 0.3821, "width_ratio": 0.0966, "height_ratio": 0.0626, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_133", "display_cluster_candidate_id": "disp_26_0", "layout_region": "display_zone", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"], "asset_family_hint": "figure_like", "asset_family_confidence": 0.7, "asset_family_evidence": ["raw_label:image"]}
+{"paper_id": "2HEUD5P9", "page": 13, "block_id": 24, "raw_label": "image", "raw_order": null, "bbox": [848, 651, 1086, 749], "text": "", "page_width": 1191, "page_height": 1565, "role": "figure_asset", "role_confidence": 0.85, "evidence": ["media label: image"], "seed_role": "media_asset", "seed_confidence": 0.85, "seed_evidence": ["media label: image"], "span_metadata": null, "raw_observation": {"block_id": 24, "page": 13, "raw_label": "image", "text": "", "bbox": [848, 651, 1086, 749], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "empty", "raw_marker": null, "number": null, "kind": null, "normalized_text": ""}, "layout_signature": {"width": 238, "width_bucket": 250, "height": 98, "left": 848, "top": 651, "right": 1086, "bottom": 749, "x_center": 967.0, "x_center_bucket": 975, "y_center": 700.0, "x_ratio": 0.8119, "y_ratio": 0.4473, "width_ratio": 0.1998, "height_ratio": 0.0626, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_134", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"], "asset_family_hint": "figure_like", "asset_family_confidence": 0.7, "asset_family_evidence": ["raw_label:image"]}
+{"paper_id": "2HEUD5P9", "page": 13, "block_id": 25, "raw_label": "figure_title", "raw_order": null, "bbox": [112, 793, 141, 817], "text": "(F)", "page_width": 1191, "page_height": 1565, "role": "figure_inner_text", "role_confidence": 0.9, "evidence": ["panel label / figure inner text: (F)"], "seed_role": "figure_inner_text", "seed_confidence": 0.9, "seed_evidence": ["panel label / figure inner text: (F)"], "span_metadata": null, "raw_observation": {"block_id": 25, "page": 13, "raw_label": "figure_title", "text": "(F)", "bbox": [112, 793, 141, 817], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "panel_label", "raw_marker": "(F)", "number": null, "kind": "panel_label", "normalized_text": "(F)"}, "layout_signature": {"width": 29, "width_bucket": 25, "height": 24, "left": 112, "top": 793, "right": 141, "bottom": 817, "x_center": 126.5, "x_center_bucket": 125, "y_center": 805.0, "x_ratio": 0.1062, "y_ratio": 0.5144, "width_ratio": 0.0243, "height_ratio": 0.0153, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "display_zone", "style_family": "legend_like", "style_family_authority": "figure_marker", "reading_band_id": "band_131", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 13, "block_id": 26, "raw_label": "figure_title", "raw_order": null, "bbox": [688, 765, 708, 790], "text": "(1)", "page_width": 1191, "page_height": 1565, "role": "figure_caption", "role_confidence": 0.85, "evidence": ["figure_title label: (1)"], "seed_role": "figure_caption", "seed_confidence": 0.85, "seed_evidence": ["figure_title label: (1)"], "span_metadata": null, "raw_observation": {"block_id": 26, "page": 13, "raw_label": "figure_title", "text": "(1)", "bbox": [688, 765, 708, 790], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "short_fragment", "raw_marker": "(1)", "number": null, "kind": "short_fragment", "normalized_text": "(1)"}, "layout_signature": {"width": 20, "width_bucket": 25, "height": 25, "left": 688, "top": 765, "right": 708, "bottom": 790, "x_center": 698.0, "x_center_bucket": 700, "y_center": 777.5, "x_ratio": 0.5861, "y_ratio": 0.4968, "width_ratio": 0.0168, "height_ratio": 0.016, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_135", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "hard", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "accepted_figure_caption_artifact", "role_evidence": ["figure caption matched accepted figure artifact"], "caption_score": {"score": 0.0, "decision": "rejected", "evidence": []}}
+{"paper_id": "2HEUD5P9", "page": 13, "block_id": 27, "raw_label": "image", "raw_order": null, "bbox": [117, 798, 651, 1009], "text": "", "page_width": 1191, "page_height": 1565, "role": "figure_asset", "role_confidence": 0.85, "evidence": ["media label: image"], "seed_role": "media_asset", "seed_confidence": 0.85, "seed_evidence": ["media label: image"], "span_metadata": null, "raw_observation": {"block_id": 27, "page": 13, "raw_label": "image", "text": "", "bbox": [117, 798, 651, 1009], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "empty", "raw_marker": null, "number": null, "kind": null, "normalized_text": ""}, "layout_signature": {"width": 534, "width_bucket": 525, "height": 211, "left": 117, "top": 798, "right": 651, "bottom": 1009, "x_center": 384.0, "x_center_bucket": 375, "y_center": 903.5, "x_ratio": 0.3224, "y_ratio": 0.5773, "width_ratio": 0.4484, "height_ratio": 0.1348, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_137", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"], "asset_family_hint": "figure_like", "asset_family_confidence": 0.7, "asset_family_evidence": ["raw_label:image"]}
+{"paper_id": "2HEUD5P9", "page": 13, "block_id": 28, "raw_label": "figure_title", "raw_order": null, "bbox": [914, 765, 940, 788], "text": "(J)", "page_width": 1191, "page_height": 1565, "role": "figure_inner_text", "role_confidence": 0.9, "evidence": ["panel label / figure inner text: (J)"], "seed_role": "figure_inner_text", "seed_confidence": 0.9, "seed_evidence": ["panel label / figure inner text: (J)"], "span_metadata": null, "raw_observation": {"block_id": 28, "page": 13, "raw_label": "figure_title", "text": "(J)", "bbox": [914, 765, 940, 788], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "panel_label", "raw_marker": "(J)", "number": null, "kind": "panel_label", "normalized_text": "(J)"}, "layout_signature": {"width": 26, "width_bucket": 25, "height": 23, "left": 914, "top": 765, "right": 940, "bottom": 788, "x_center": 927.0, "x_center_bucket": 925, "y_center": 776.5, "x_ratio": 0.7783, "y_ratio": 0.4962, "width_ratio": 0.0218, "height_ratio": 0.0147, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "display_zone", "style_family": "legend_like", "style_family_authority": "figure_marker", "reading_band_id": "band_137", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 13, "block_id": 29, "raw_label": "image", "raw_order": null, "bbox": [693, 767, 911, 1020], "text": "", "page_width": 1191, "page_height": 1565, "role": "figure_asset", "role_confidence": 0.85, "evidence": ["media label: image"], "seed_role": "media_asset", "seed_confidence": 0.85, "seed_evidence": ["media label: image"], "span_metadata": null, "raw_observation": {"block_id": 29, "page": 13, "raw_label": "image", "text": "", "bbox": [693, 767, 911, 1020], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "empty", "raw_marker": null, "number": null, "kind": null, "normalized_text": ""}, "layout_signature": {"width": 218, "width_bucket": 225, "height": 253, "left": 693, "top": 767, "right": 911, "bottom": 1020, "x_center": 802.0, "x_center_bucket": 800, "y_center": 893.5, "x_ratio": 0.6734, "y_ratio": 0.5709, "width_ratio": 0.183, "height_ratio": 0.1617, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_126", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"], "asset_family_hint": "figure_like", "asset_family_confidence": 0.7, "asset_family_evidence": ["raw_label:image"]}
+{"paper_id": "2HEUD5P9", "page": 13, "block_id": 30, "raw_label": "chart", "raw_order": null, "bbox": [914, 781, 1078, 899], "text": "", "page_width": 1191, "page_height": 1565, "role": "figure_asset", "role_confidence": 0.85, "evidence": ["media label: chart"], "seed_role": "media_asset", "seed_confidence": 0.85, "seed_evidence": ["media label: chart"], "span_metadata": null, "raw_observation": {"block_id": 30, "page": 13, "raw_label": "chart", "text": "", "bbox": [914, 781, 1078, 899], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "empty", "raw_marker": null, "number": null, "kind": null, "normalized_text": ""}, "layout_signature": {"width": 164, "width_bucket": 175, "height": 118, "left": 914, "top": 781, "right": 1078, "bottom": 899, "x_center": 996.0, "x_center_bucket": 1000, "y_center": 840.0, "x_ratio": 0.8363, "y_ratio": 0.5367, "width_ratio": 0.1377, "height_ratio": 0.0754, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_126", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"], "asset_family_hint": "figure_like", "asset_family_confidence": 0.7, "asset_family_evidence": ["raw_label:chart"]}
+{"paper_id": "2HEUD5P9", "page": 13, "block_id": 31, "raw_label": "figure_title", "raw_order": null, "bbox": [912, 890, 940, 915], "text": "(K)", "page_width": 1191, "page_height": 1565, "role": "figure_inner_text", "role_confidence": 0.9, "evidence": ["panel label / figure inner text: (K)"], "seed_role": "figure_inner_text", "seed_confidence": 0.9, "seed_evidence": ["panel label / figure inner text: (K)"], "span_metadata": null, "raw_observation": {"block_id": 31, "page": 13, "raw_label": "figure_title", "text": "(K)", "bbox": [912, 890, 940, 915], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "panel_label", "raw_marker": "(K)", "number": null, "kind": "panel_label", "normalized_text": "(K)"}, "layout_signature": {"width": 28, "width_bucket": 25, "height": 25, "left": 912, "top": 890, "right": 940, "bottom": 915, "x_center": 926.0, "x_center_bucket": 925, "y_center": 902.5, "x_ratio": 0.7775, "y_ratio": 0.5767, "width_ratio": 0.0235, "height_ratio": 0.016, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "display_zone", "style_family": "legend_like", "style_family_authority": "figure_marker", "reading_band_id": "band_126", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 13, "block_id": 32, "raw_label": "chart", "raw_order": null, "bbox": [914, 906, 1080, 1020], "text": "", "page_width": 1191, "page_height": 1565, "role": "figure_asset", "role_confidence": 0.85, "evidence": ["media label: chart"], "seed_role": "media_asset", "seed_confidence": 0.85, "seed_evidence": ["media label: chart"], "span_metadata": null, "raw_observation": {"block_id": 32, "page": 13, "raw_label": "chart", "text": "", "bbox": [914, 906, 1080, 1020], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "empty", "raw_marker": null, "number": null, "kind": null, "normalized_text": ""}, "layout_signature": {"width": 166, "width_bucket": 175, "height": 114, "left": 914, "top": 906, "right": 1080, "bottom": 1020, "x_center": 997.0, "x_center_bucket": 1000, "y_center": 963.0, "x_ratio": 0.8371, "y_ratio": 0.6153, "width_ratio": 0.1394, "height_ratio": 0.0728, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_126", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"], "asset_family_hint": "figure_like", "asset_family_confidence": 0.7, "asset_family_evidence": ["raw_label:chart"]}
+{"paper_id": "2HEUD5P9", "page": 13, "block_id": 33, "raw_label": "figure_title", "raw_order": null, "bbox": [110, 1025, 140, 1050], "text": "(G)", "page_width": 1191, "page_height": 1565, "role": "figure_inner_text", "role_confidence": 0.9, "evidence": ["panel label / figure inner text: (G)"], "seed_role": "figure_inner_text", "seed_confidence": 0.9, "seed_evidence": ["panel label / figure inner text: (G)"], "span_metadata": null, "raw_observation": {"block_id": 33, "page": 13, "raw_label": "figure_title", "text": "(G)", "bbox": [110, 1025, 140, 1050], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "panel_label", "raw_marker": "(G)", "number": null, "kind": "panel_label", "normalized_text": "(G)"}, "layout_signature": {"width": 30, "width_bucket": 25, "height": 25, "left": 110, "top": 1025, "right": 140, "bottom": 1050, "x_center": 125.0, "x_center_bucket": 125, "y_center": 1037.5, "x_ratio": 0.105, "y_ratio": 0.6629, "width_ratio": 0.0252, "height_ratio": 0.016, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "display_zone", "style_family": "legend_like", "style_family_authority": "figure_marker", "reading_band_id": "band_126", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 13, "block_id": 34, "raw_label": "image", "raw_order": null, "bbox": [124, 1030, 399, 1220], "text": "", "page_width": 1191, "page_height": 1565, "role": "figure_asset", "role_confidence": 0.85, "evidence": ["media label: image"], "seed_role": "media_asset", "seed_confidence": 0.85, "seed_evidence": ["media label: image"], "span_metadata": null, "raw_observation": {"block_id": 34, "page": 13, "raw_label": "image", "text": "", "bbox": [124, 1030, 399, 1220], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "empty", "raw_marker": null, "number": null, "kind": null, "normalized_text": ""}, "layout_signature": {"width": 275, "width_bucket": 275, "height": 190, "left": 124, "top": 1030, "right": 399, "bottom": 1220, "x_center": 261.5, "x_center_bucket": 250, "y_center": 1125.0, "x_ratio": 0.2196, "y_ratio": 0.7188, "width_ratio": 0.2309, "height_ratio": 0.1214, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_124", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"], "asset_family_hint": "figure_like", "asset_family_confidence": 0.7, "asset_family_evidence": ["raw_label:image"]}
+{"paper_id": "2HEUD5P9", "page": 13, "block_id": 35, "raw_label": "figure_title", "raw_order": null, "bbox": [417, 1025, 447, 1050], "text": "(H)", "page_width": 1191, "page_height": 1565, "role": "figure_inner_text", "role_confidence": 0.9, "evidence": ["panel label / figure inner text: (H)"], "seed_role": "figure_inner_text", "seed_confidence": 0.9, "seed_evidence": ["panel label / figure inner text: (H)"], "span_metadata": null, "raw_observation": {"block_id": 35, "page": 13, "raw_label": "figure_title", "text": "(H)", "bbox": [417, 1025, 447, 1050], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "panel_label", "raw_marker": "(H)", "number": null, "kind": "panel_label", "normalized_text": "(H)"}, "layout_signature": {"width": 30, "width_bucket": 25, "height": 25, "left": 417, "top": 1025, "right": 447, "bottom": 1050, "x_center": 432.0, "x_center_bucket": 425, "y_center": 1037.5, "x_ratio": 0.3627, "y_ratio": 0.6629, "width_ratio": 0.0252, "height_ratio": 0.016, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "display_zone", "style_family": "legend_like", "style_family_authority": "figure_marker", "reading_band_id": "band_127", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 13, "block_id": 36, "raw_label": "figure_title", "raw_order": null, "bbox": [722, 1019, 749, 1045], "text": "(L)", "page_width": 1191, "page_height": 1565, "role": "figure_inner_text", "role_confidence": 0.9, "evidence": ["panel label / figure inner text: (L)"], "seed_role": "figure_inner_text", "seed_confidence": 0.9, "seed_evidence": ["panel label / figure inner text: (L)"], "span_metadata": null, "raw_observation": {"block_id": 36, "page": 13, "raw_label": "figure_title", "text": "(L)", "bbox": [722, 1019, 749, 1045], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "panel_label", "raw_marker": "(L)", "number": null, "kind": "panel_label", "normalized_text": "(L)"}, "layout_signature": {"width": 27, "width_bucket": 25, "height": 26, "left": 722, "top": 1019, "right": 749, "bottom": 1045, "x_center": 735.5, "x_center_bucket": 725, "y_center": 1032.0, "x_ratio": 0.6175, "y_ratio": 0.6594, "width_ratio": 0.0227, "height_ratio": 0.0166, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "display_zone", "style_family": "legend_like", "style_family_authority": "figure_marker", "reading_band_id": "band_127", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 13, "block_id": 37, "raw_label": "chart", "raw_order": null, "bbox": [422, 1028, 701, 1230], "text": "", "page_width": 1191, "page_height": 1565, "role": "figure_asset", "role_confidence": 0.85, "evidence": ["media label: chart"], "seed_role": "media_asset", "seed_confidence": 0.85, "seed_evidence": ["media label: chart"], "span_metadata": null, "raw_observation": {"block_id": 37, "page": 13, "raw_label": "chart", "text": "", "bbox": [422, 1028, 701, 1230], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "empty", "raw_marker": null, "number": null, "kind": null, "normalized_text": ""}, "layout_signature": {"width": 279, "width_bucket": 275, "height": 202, "left": 422, "top": 1028, "right": 701, "bottom": 1230, "x_center": 561.5, "x_center_bucket": 550, "y_center": 1129.0, "x_ratio": 0.4715, "y_ratio": 0.7214, "width_ratio": 0.2343, "height_ratio": 0.1291, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_127", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"], "asset_family_hint": "figure_like", "asset_family_confidence": 0.7, "asset_family_evidence": ["raw_label:chart"]}
+{"paper_id": "2HEUD5P9", "page": 13, "block_id": 38, "raw_label": "image", "raw_order": null, "bbox": [730, 1026, 1046, 1242], "text": "", "page_width": 1191, "page_height": 1565, "role": "figure_asset", "role_confidence": 0.85, "evidence": ["media label: image"], "seed_role": "media_asset", "seed_confidence": 0.85, "seed_evidence": ["media label: image"], "span_metadata": null, "raw_observation": {"block_id": 38, "page": 13, "raw_label": "image", "text": "", "bbox": [730, 1026, 1046, 1242], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "empty", "raw_marker": null, "number": null, "kind": null, "normalized_text": ""}, "layout_signature": {"width": 316, "width_bucket": 325, "height": 216, "left": 730, "top": 1026, "right": 1046, "bottom": 1242, "x_center": 888.0, "x_center_bucket": 900, "y_center": 1134.0, "x_ratio": 0.7456, "y_ratio": 0.7246, "width_ratio": 0.2653, "height_ratio": 0.138, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_127", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"], "asset_family_hint": "figure_like", "asset_family_confidence": 0.7, "asset_family_evidence": ["raw_label:image"]}
+{"paper_id": "2HEUD5P9", "page": 13, "block_id": 39, "raw_label": "figure_title", "raw_order": null, "bbox": [95, 1254, 1100, 1428], "text": "Figure 5. A) ALP staining and ARS staining of Control, Let-7d, LDH and LDH/let-7d groups on day 7 and day 14, respectively. Scale bars: 500 $ \\mu $m. B) LDH/let-7d-incorporated fibrin scaffolds promoted the subcutaneous ectopic osteogenesis of BMSCs in nude mice. Representative reconstructed micro-CT images. Scale bars: 100 $ \\mu $m. $ ^{[115]} $ Copyright 2021, American Chemical Society. C,D) Optical photograph of subcutaneous capsules (C) and SEM views (D) of Mg, Mg-Mg(OH) $ _{2} $, Mg-LDH after implantation for 4 weeks. E) Photomicrographs of histological section of Mg, Mg-Mg(OH) $ _{2} $, Mg-LDH after implantation for 4 and 8 weeks. The red asterisk represented the sample and blue arrow indicated neutrophils. $ ^{[116]} $ Copyright 2020, Elsevier. F–H) Micro-CT(F), BMD (G) and BV/TV rate (H) of control, LDH/CS and SrFe $ _{12} $O $ _{19} $-LDH/CS. $ ^{[120]} $ Copyright 2022, Elsevier. I–L) Three-dimensional reconstruction images of Micro-CT results of the various samples after implantation in femur of SD rat for 8 and 12 weeks (I), yellow section indicate new bone. Calculated bone volume/tissue volume (BV/TV) (J) and trabecular thickness (Tb.Th) of the various samples after implantation for 8 and 12 weeks (K). VG staining of the various samples after femur implantation for 8 and 12 weeks (L). $ ^{[123]} $ Copyright 2022, Elsevier.", "page_width": 1191, "page_height": 1565, "role": "figure_caption", "role_confidence": 0.92, "evidence": ["figure_title label: Figure 5. A) ALP staining and ARS staining of Control, Let-7"], "seed_role": "figure_caption", "seed_confidence": 0.92, "seed_evidence": ["figure_title label: Figure 5. A) ALP staining and ARS staining of Control, Let-7"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "STIX-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "STIX-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "STIX-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "STIX-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaSansPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaSansPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaSansPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaSansPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaSansPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaSansPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaSansPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaSansPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaSansPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaSansPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaSansPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaSansPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 39, "page": 13, "raw_label": "figure_title", "text": "Figure 5. A) ALP staining and ARS staining of Control, Let-7d, LDH and LDH/let-7d groups on day 7 and day 14, respectively. Scale bars: 500 $ \\mu $m. B) LDH/let-7d-incorporated fibrin scaffolds promoted the subcutaneous ectopic osteogenesis of BMSCs in nude mice. Representative reconstructed micro-CT images. Scale bars: 100 $ \\mu $m. $ ^{[115]} $ Copyright 2021, American Chemical Society. C,D) Optical photograph of subcutaneous capsules (C) and SEM views (D) of Mg, Mg-Mg(OH) $ _{2} $, Mg-LDH after implantation for 4 weeks. E) Photomicrographs of histological section of Mg, Mg-Mg(OH) $ _{2} $, Mg-LDH after implantation for 4 and 8 weeks. The red asterisk represented the sample and blue arrow indicated neutrophils. $ ^{[116]} $ Copyright 2020, Elsevier. F–H) Micro-CT(F), BMD (G) and BV/TV rate (H) of control, LDH/CS and SrFe $ _{12} $O $ _{19} $-LDH/CS. $ ^{[120]} $ Copyright 2022, Elsevier. I–L) Three-dimensional reconstruction images of Micro-CT results of the various samples after implantation in femur of SD rat for 8 and 12 weeks (I), yellow section indicate new bone. Calculated bone volume/tissue volume (BV/TV) (J) and trabecular thickness (Tb.Th) of the various samples after implantation for 8 and 12 weeks (K). VG staining of the various samples after femur implantation for 8 and 12 weeks (L). $ ^{[123]} $ Copyright 2022, Elsevier.", "bbox": [95, 1254, 1100, 1428], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "figure_number", "raw_marker": "Figure 5", "number": 5, "kind": "figure", "normalized_text": "Figure 5. A) ALP staining and ARS staining of Control, Let-7d, LDH and LDH/let-7d groups on day 7 and day 14, respectively. Scale bars: 500 $ \\mu $m. B) LDH/let-7d-incorporated fibrin scaffolds promoted the subcutaneous ectopic osteogenesis of BMSCs in nude mice. Representative reconstructed micro-CT images. Scale bars: 100 $ \\mu $m. $ ^{[115]} $ Copyright 2021, American Chemical Society. C,D) Optical photograph of subcutaneous capsules (C) and SEM views (D) of Mg, Mg-Mg(OH) $ _{2} $, Mg-LDH after implantation for 4 weeks. E) Photomicrographs of histological section of Mg, Mg-Mg(OH) $ _{2} $, Mg-LDH after implantation for 4 and 8 weeks. The red asterisk represented the sample and blue arrow indicated neutrophils. $ ^{[116]} $ Copyright 2020, Elsevier. F–H) Micro-CT(F), BMD (G) and BV/TV rate (H) of control, LDH/CS and SrFe $ _{12} $O $ _{19} $-LDH/CS. $ ^{[120]} $ Copyright 2022, Elsevier. I–L) Three-dimensional reconstruction images of Micro-CT results of the various samples after implantation in femur of SD rat for 8 and 12 weeks (I), yellow section indicate new bone. Calculated bone volume/tissue volume (BV/TV) (J) and trabecular thickness (Tb.Th) of the various samples after implantation for 8 and 12 weeks (K). VG staining of the various samples after femur implantation for 8 and 12 weeks (L). $ ^{[123]} $ Copyright 2022, Elsevier."}, "layout_signature": {"width": 1005, "width_bucket": 1000, "height": 174, "left": 95, "top": 1254, "right": 1100, "bottom": 1428, "x_center": 597.5, "x_center_bucket": 600, "y_center": 1341.0, "x_ratio": 0.5017, "y_ratio": 0.8569, "width_ratio": 0.8438, "height_ratio": 0.1112, "line_count": 1}, "span_signature": {"font_size": 7.8, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Bold", "bold": true, "italic": true, "span_count": 185}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "display_zone", "style_family": "legend_like", "style_family_authority": "figure_marker", "reading_band_id": "band_127", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.0, "decision": "body", "evidence": []}, "role_verification_status": "ACCEPT", "role_source": "accepted_figure_caption_artifact", "role_evidence": ["figure caption matched accepted figure artifact"]}
+{"paper_id": "2HEUD5P9", "page": 13, "block_id": 40, "raw_label": "footer", "raw_order": null, "bbox": [99, 1487, 289, 1505], "text": "Small Methods 2024, 8, 2301283", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["footer label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["footer label"], "span_metadata": [{"size": 6.973800182342529, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 40, "page": 13, "raw_label": "footer", "text": "Small Methods 2024, 8, 2301283", "bbox": [99, 1487, 289, 1505], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "Small Methods 2024, 8, 2301283"}, "layout_signature": {"width": 190, "width_bucket": 200, "height": 18, "left": 99, "top": 1487, "right": 289, "bottom": 1505, "x_center": 194.0, "x_center_bucket": 200, "y_center": 1496.0, "x_ratio": 0.1629, "y_ratio": 0.9559, "width_ratio": 0.1595, "height_ratio": 0.0115, "line_count": 1}, "span_signature": {"font_size": 6.97, "font_size_median": 6.97, "font_size_bucket": 7.0, "font_family_norm": "ScalaSansPro-Italic", "bold": true, "italic": true, "span_count": 5}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_127", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 13, "block_id": 41, "raw_label": "number", "raw_order": null, "bbox": [526, 1484, 669, 1508], "text": "2301283 (13 of 27)", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["page number label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["page number label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaSansPro-Bold", "flags": 20, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 41, "page": 13, "raw_label": "number", "text": "2301283 (13 of 27)", "bbox": [526, 1484, 669, 1508], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_dot", "raw_marker": "2301283", "number": 2301283, "kind": "reference", "normalized_text": "2301283 (13 of 27)"}, "layout_signature": {"width": 143, "width_bucket": 150, "height": 24, "left": 526, "top": 1484, "right": 669, "bottom": 1508, "x_center": 597.5, "x_center_bucket": 600, "y_center": 1496.0, "x_ratio": 0.5017, "y_ratio": 0.9559, "width_ratio": 0.1201, "height_ratio": 0.0153, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaSansPro-Bold", "bold": true, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "reference_like", "style_family_authority": "reference_family_anchor", "reading_band_id": "band_127", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 13, "block_id": 42, "raw_label": "footer", "raw_order": null, "bbox": [937, 1486, 1096, 1506], "text": "© 2024 Wiley-VCH GmbH", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["footer label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["footer label"], "span_metadata": [{"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 42, "page": 13, "raw_label": "footer", "text": "© 2024 Wiley-VCH GmbH", "bbox": [937, 1486, 1096, 1506], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "© 2024 Wiley-VCH GmbH"}, "layout_signature": {"width": 159, "width_bucket": 150, "height": 20, "left": 937, "top": 1486, "right": 1096, "bottom": 1506, "x_center": 1016.5, "x_center_bucket": 1025, "y_center": 1496.0, "x_ratio": 0.8535, "y_ratio": 0.9559, "width_ratio": 0.1335, "height_ratio": 0.0128, "line_count": 1}, "span_signature": {"font_size": 6.97, "font_size_median": 6.97, "font_size_bucket": 7.0, "font_family_norm": "ScalaSansPro-Regular", "bold": false, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_127", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 13, "block_id": 43, "raw_label": "aside_text", "raw_order": null, "bbox": [1147, 34, 1171, 1471], "text": "23669608, 2024, 8. Downloaded from https://onlinelibrary.wiley.com/doi/10.1002/smkt.202301283 by Shandong University Library, Wiley Online Library on [18/02/2026]. See the Terms and Conditions (https://onlinelibrary.wiley.com/terms-and-conditions) on Wiley Online Library for rules of use; OA articles are governed by the applicable Creative Co", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.95, "evidence": ["margin-band narrow/tall geometry; treated as noise"], "seed_role": "noise", "seed_confidence": 0.95, "seed_evidence": ["margin-band narrow/tall geometry; treated as noise"], "span_metadata": [{"size": 5.03000020980835, "font": "Times-Roman", "flags": 4, "color": 0, "dir": [0.0, 1.0], "wmode": 0}], "raw_observation": {"block_id": 43, "page": 13, "raw_label": "aside_text", "text": "23669608, 2024, 8. Downloaded from https://onlinelibrary.wiley.com/doi/10.1002/smkt.202301283 by Shandong University Library, Wiley Online Library on [18/02/2026]. See the Terms and Conditions (https://onlinelibrary.wiley.com/terms-and-conditions) on Wiley Online Library for rules of use; OA articles are governed by the applicable Creative Co", "bbox": [1147, 34, 1171, 1471], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "23669608, 2024, 8. Downloaded from https://onlinelibrary.wiley.com/doi/10.1002/smkt.202301283 by Shandong University Library, Wiley Online Library on [18/02/2026]. See the Terms and Conditions (https://onlinelibrary.wiley.com/terms-and-conditions) on Wiley Online Library for rules of use; OA articles are governed by the applicable Creative Co"}, "layout_signature": {"width": 24, "width_bucket": 25, "height": 1437, "left": 1147, "top": 34, "right": 1171, "bottom": 1471, "x_center": 1159.0, "x_center_bucket": 1150, "y_center": 752.5, "x_ratio": 0.9731, "y_ratio": 0.4808, "width_ratio": 0.0202, "height_ratio": 0.9182, "line_count": 1}, "span_signature": {"font_size": 5.03, "font_size_median": 5.03, "font_size_bucket": 5.0, "font_family_norm": "Times-Roman", "bold": false, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_family_anchor", "reading_band_id": "band_127", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 14, "block_id": 0, "raw_label": "header", "raw_order": null, "bbox": [92, 45, 339, 116], "text": "ADVANCED\nSCIENCE NEWS\nwww.advancedsciencenews.com", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["header label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["header label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaSansPro-Bold", "flags": 20, "color": 255, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 0, "page": 14, "raw_label": "header", "text": "ADVANCED\nSCIENCE NEWS\nwww.advancedsciencenews.com", "bbox": [92, 45, 339, 116], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "ADVANCED\nSCIENCE NEWS\nwww.advancedsciencenews.com"}, "layout_signature": {"width": 247, "width_bucket": 250, "height": 71, "left": 92, "top": 45, "right": 339, "bottom": 116, "x_center": 215.5, "x_center_bucket": 225, "y_center": 80.5, "x_ratio": 0.1809, "y_ratio": 0.0514, "width_ratio": 0.2074, "height_ratio": 0.0454, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaSansPro-Bold", "bold": true, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 14, "block_id": 1, "raw_label": "header", "raw_order": null, "bbox": [997, 36, 1089, 97], "text": "small methods", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["header label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["header label"], "span_metadata": null, "raw_observation": {"block_id": 1, "page": 14, "raw_label": "header", "text": "small methods", "bbox": [997, 36, 1089, 97], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "short_fragment", "raw_marker": "small methods", "number": null, "kind": "short_fragment", "normalized_text": "small methods"}, "layout_signature": {"width": 92, "width_bucket": 100, "height": 61, "left": 997, "top": 36, "right": 1089, "bottom": 97, "x_center": 1043.0, "x_center_bucket": 1050, "y_center": 66.5, "x_ratio": 0.8757, "y_ratio": 0.0425, "width_ratio": 0.0772, "height_ratio": 0.039, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": true, "_container_bbox": [1000.0802235557833, 37.836628863963085, 1078.3616835103696, 91.04600210547972], "_container_text": "small methods", "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_142", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.6, "decision": "structured_insert_candidate", "evidence": ["visual_container", "narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 14, "block_id": 2, "raw_label": "header", "raw_order": null, "bbox": [896, 96, 1090, 117], "text": "www.small-methods.com", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["header label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["header label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaSansPro-Bold", "flags": 20, "color": 255, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 2, "page": 14, "raw_label": "header", "text": "www.small-methods.com", "bbox": [896, 96, 1090, 117], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "www.small-methods.com"}, "layout_signature": {"width": 194, "width_bucket": 200, "height": 21, "left": 896, "top": 96, "right": 1090, "bottom": 117, "x_center": 993.0, "x_center_bucket": 1000, "y_center": 106.5, "x_ratio": 0.8338, "y_ratio": 0.0681, "width_ratio": 0.1629, "height_ratio": 0.0134, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaSansPro-Bold", "bold": true, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_142", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 14, "block_id": 3, "raw_label": "paragraph_title", "raw_order": 1, "bbox": [91, 148, 219, 171], "text": "2.5. Composites", "page_width": 1191, "page_height": 1565, "role": "subsection_heading", "role_confidence": 0.85, "evidence": ["paragraph_title label with numbering: 2.5. Composites"], "seed_role": "subsection_heading", "seed_confidence": 0.85, "seed_evidence": ["paragraph_title label with numbering: 2.5. Composites"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaSansPro-Bold", "flags": 20, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 3, "page": 14, "raw_label": "paragraph_title", "text": "2.5. Composites", "bbox": [91, 148, 219, 171], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "heading_numbered", "raw_marker": "2.5", "number": "2.5", "kind": "heading", "normalized_text": "2.5. Composites"}, "layout_signature": {"width": 128, "width_bucket": 125, "height": 23, "left": 91, "top": 148, "right": 219, "bottom": 171, "x_center": 155.0, "x_center_bucket": 150, "y_center": 159.5, "x_ratio": 0.1301, "y_ratio": 0.1019, "width_ratio": 0.1075, "height_ratio": 0.0147, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaSansPro-Bold", "bold": true, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_139", "display_cluster_candidate_id": "disp_27_0", "layout_region": "display_zone", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "accepted_heading", "role_evidence": ["heading verified by heading artifact"]}
+{"paper_id": "2HEUD5P9", "page": 14, "block_id": 4, "raw_label": "text", "raw_order": 2, "bbox": [89, 192, 581, 391], "text": "As mentioned above, each material has merits and shortcomings in bone tissue engineering. The main limitations of individual materials are the brittleness and low degradability of ceramics, weak mechanical strength and toxicity of the degradation products of polymers, and stress shielding effects and nonbiodegradability of metals, which can be resolved by combining several materials. Specifically, composites have been developed to mimic the structure, mechanical properties, biological activity, and osteoconductivity of real bone tissue.", "page_width": 1191, "page_height": 1565, "role": "body_paragraph", "role_confidence": 0.6, "evidence": ["default body_paragraph for text label"], "seed_role": "body_paragraph", "seed_confidence": 0.6, "seed_evidence": ["default body_paragraph for text label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 4, "page": 14, "raw_label": "text", "text": "As mentioned above, each material has merits and shortcomings in bone tissue engineering. The main limitations of individual materials are the brittleness and low degradability of ceramics, weak mechanical strength and toxicity of the degradation products of polymers, and stress shielding effects and nonbiodegradability of metals, which can be resolved by combining several materials. Specifically, composites have been developed to mimic the structure, mechanical properties, biological activity, and osteoconductivity of real bone tissue.", "bbox": [89, 192, 581, 391], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "As mentioned above, each material has merits and shortcomings in bone tissue engineering. The main limitations of individual materials are the brittleness and low degradability of ceramics, weak mechanical strength and toxicity of the degradation products of polymers, and stress shielding effects and nonbiodegradability of metals, which can be resolved by combining several materials. Specifically, composites have been developed to mimic the structure, mechanical properties, biological activity, and osteoconductivity of real bone tissue."}, "layout_signature": {"width": 492, "width_bucket": 500, "height": 199, "left": 89, "top": 192, "right": 581, "bottom": 391, "x_center": 335.0, "x_center_bucket": 325, "y_center": 291.5, "x_ratio": 0.2813, "y_ratio": 0.1863, "width_ratio": 0.4131, "height_ratio": 0.1272, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaPro-Regular", "bold": false, "italic": true, "span_count": 85}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_140", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 14, "block_id": 5, "raw_label": "text", "raw_order": 3, "bbox": [89, 392, 583, 1245], "text": "Composite scaffolds have been used to regulate scaffold properties and repair bone defects. Numerous studies have applied ceramic and polymer composites in bone tissue engineering. For example, a chitosan/HAP/ $ \\beta $-TCP/ composite is cytocompatible and promoted cell proliferation, which is required for efficient new bone formation. $ ^{[124]} $ The porous collagen-carboxymethyl cellulose/HAP composite exhibited increased compressive strength and cell proliferation. $ ^{[125]} $ The addition of HAP improved the mechanical properties of the PLA scaffold, as well as the cell proliferation and osteogenic ability. $ ^{[126,127]} $ Composites of ceramics and metals have been proposed to counteract the corrosion of metals, and their superior mechanical properties are retained. Titanium-reinforced CaP implants promote in situ cranial defect repair and osseointegration. $ ^{[128]} $ Nano-HAP reinforces the bioactivity of porous magnesium alloy foam, which is an excellent scaffold for bone regeneration. $ ^{[129]} $ Metal–polymer composites for use in bone repair have also been investigated. Chitosan- $ TiO_{2} $ nanotube scaffolds exhibited an improved compressive modulus and a lower degradation rate, and the functionalization of composites with $ Ca^{2+} $ ions promoted cell adhesion, proliferation, and early osteogenic differentiation. $ ^{[130]} $ A PCL-BG coating improved the bioactivity, mechanical integrity, degradation resistance, and apatite layer formation of a magnesium scaffold. $ ^{[131]} $ In addition, some composites can be used for osteochondral repair. Three-layer chitosan/silk fibroin/HAP scaffolds synthesized by electrospinning could mimic the subchondral bone, calcified, and chondral layers to facilitate osteochondral repair. $ ^{[132]} $ Bilayered chitosan/chitosan- $ \\beta $-TCP composite scaffolds manufactured by lyophilization could maintain the viability and proliferation of cells seeded into both layers, which differentiated into chondrogenic and osteogenic lineages. $ ^{[133]} $ A bilayer hydrogel scaffold with a PGA/chitosan/cellulose hydrogel cartilage layer and a porous nano-HA-containing PGA/chitosan/cellulose hydrogel osteogenic layer was successfully prepared based on the bionic principle, the addition of $ Mg^{2+} $ and $ Cu^{2+} $ ions modulated the mechanical and biological properties of the composite to be similar to those of natural cartilage. Bioactive ions also endow scaffolds with excellent antibacterial, osteogenic, and chondrogenic properties. $ ^{[134]} $", "page_width": 1191, "page_height": 1565, "role": "body_paragraph", "role_confidence": 0.6, "evidence": ["default body_paragraph for text label"], "seed_role": "body_paragraph", "seed_confidence": 0.6, "seed_evidence": ["default body_paragraph for text label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "STIXMath-Italic", "flags": 6, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "STIXMath-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "STIXMath-Italic", "flags": 6, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "STIXMath-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "STIXMath-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 5, "page": 14, "raw_label": "text", "text": "Composite scaffolds have been used to regulate scaffold properties and repair bone defects. Numerous studies have applied ceramic and polymer composites in bone tissue engineering. For example, a chitosan/HAP/ $ \\beta $-TCP/ composite is cytocompatible and promoted cell proliferation, which is required for efficient new bone formation. $ ^{[124]} $ The porous collagen-carboxymethyl cellulose/HAP composite exhibited increased compressive strength and cell proliferation. $ ^{[125]} $ The addition of HAP improved the mechanical properties of the PLA scaffold, as well as the cell proliferation and osteogenic ability. $ ^{[126,127]} $ Composites of ceramics and metals have been proposed to counteract the corrosion of metals, and their superior mechanical properties are retained. Titanium-reinforced CaP implants promote in situ cranial defect repair and osseointegration. $ ^{[128]} $ Nano-HAP reinforces the bioactivity of porous magnesium alloy foam, which is an excellent scaffold for bone regeneration. $ ^{[129]} $ Metal–polymer composites for use in bone repair have also been investigated. Chitosan- $ TiO_{2} $ nanotube scaffolds exhibited an improved compressive modulus and a lower degradation rate, and the functionalization of composites with $ Ca^{2+} $ ions promoted cell adhesion, proliferation, and early osteogenic differentiation. $ ^{[130]} $ A PCL-BG coating improved the bioactivity, mechanical integrity, degradation resistance, and apatite layer formation of a magnesium scaffold. $ ^{[131]} $ In addition, some composites can be used for osteochondral repair. Three-layer chitosan/silk fibroin/HAP scaffolds synthesized by electrospinning could mimic the subchondral bone, calcified, and chondral layers to facilitate osteochondral repair. $ ^{[132]} $ Bilayered chitosan/chitosan- $ \\beta $-TCP composite scaffolds manufactured by lyophilization could maintain the viability and proliferation of cells seeded into both layers, which differentiated into chondrogenic and osteogenic lineages. $ ^{[133]} $ A bilayer hydrogel scaffold with a PGA/chitosan/cellulose hydrogel cartilage layer and a porous nano-HA-containing PGA/chitosan/cellulose hydrogel osteogenic layer was successfully prepared based on the bionic principle, the addition of $ Mg^{2+} $ and $ Cu^{2+} $ ions modulated the mechanical and biological properties of the composite to be similar to those of natural cartilage. Bioactive ions also endow scaffolds with excellent antibacterial, osteogenic, and chondrogenic properties. $ ^{[134]} $", "bbox": [89, 392, 583, 1245], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "Composite scaffolds have been used to regulate scaffold properties and repair bone defects. Numerous studies have applied ceramic and polymer composites in bone tissue engineering. For example, a chitosan/HAP/ $ \\beta $-TCP/ composite is cytocompatible and promoted cell proliferation, which is required for efficient new bone formation. $ ^{[124]} $ The porous collagen-carboxymethyl cellulose/HAP composite exhibited increased compressive strength and cell proliferation. $ ^{[125]} $ The addition of HAP improved the mechanical properties of the PLA scaffold, as well as the cell proliferation and osteogenic ability. $ ^{[126,127]} $ Composites of ceramics and metals have been proposed to counteract the corrosion of metals, and their superior mechanical properties are retained. Titanium-reinforced CaP implants promote in situ cranial defect repair and osseointegration. $ ^{[128]} $ Nano-HAP reinforces the bioactivity of porous magnesium alloy foam, which is an excellent scaffold for bone regeneration. $ ^{[129]} $ Metal–polymer composites for use in bone repair have also been investigated. Chitosan- $ TiO_{2} $ nanotube scaffolds exhibited an improved compressive modulus and a lower degradation rate, and the functionalization of composites with $ Ca^{2+} $ ions promoted cell adhesion, proliferation, and early osteogenic differentiation. $ ^{[130]} $ A PCL-BG coating improved the bioactivity, mechanical integrity, degradation resistance, and apatite layer formation of a magnesium scaffold. $ ^{[131]} $ In addition, some composites can be used for osteochondral repair. Three-layer chitosan/silk fibroin/HAP scaffolds synthesized by electrospinning could mimic the subchondral bone, calcified, and chondral layers to facilitate osteochondral repair. $ ^{[132]} $ Bilayered chitosan/chitosan- $ \\beta $-TCP composite scaffolds manufactured by lyophilization could maintain the viability and proliferation of cells seeded into both layers, which differentiated into chondrogenic and osteogenic lineages. $ ^{[133]} $ A bilayer hydrogel scaffold with a PGA/chitosan/cellulose hydrogel cartilage layer and a porous nano-HA-containing PGA/chitosan/cellulose hydrogel osteogenic layer was successfully prepared based on the bionic principle, the addition of $ Mg^{2+} $ and $ Cu^{2+} $ ions modulated the mechanical and biological properties of the composite to be similar to those of natural cartilage. Bioactive ions also endow scaffolds with excellent antibacterial, osteogenic, and chondrogenic properties. $ ^{[134]} $"}, "layout_signature": {"width": 494, "width_bucket": 500, "height": 853, "left": 89, "top": 392, "right": 583, "bottom": 1245, "x_center": 336.0, "x_center_bucket": 325, "y_center": 818.5, "x_ratio": 0.2821, "y_ratio": 0.523, "width_ratio": 0.4148, "height_ratio": 0.545, "line_count": 1}, "span_signature": {"font_size": 8.71, "font_size_median": 8.97, "font_size_bucket": 8.5, "font_family_norm": "ScalaPro-Regular", "bold": false, "italic": true, "span_count": 432}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_139", "display_cluster_candidate_id": "disp_27_0", "layout_region": "display_zone", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 14, "block_id": 6, "raw_label": "text", "raw_order": 4, "bbox": [89, 1244, 583, 1444], "text": "The preparation method affects the mechanical properties, thermal conductivity, heat resistance, and corrosion resistance of composite materials. For example, different preparation methods can control the distribution, morphology, and size of each component in composite materials, thereby affecting the mechanical properties of composite materials. In addition, the preparation method can also affect the interfacial bonding strength between the components in composite materials, thereby affecting the heat resistance and corrosion resistance of composite materials. In summary, the preparation method of composite materials has an important influence on their properties. Through the development of new technical systems, the innovation and development of biological materials can be promoted, and their performance and effect can be improved. The new technology system can include new material synthesis method, new surface modification technology, new cell culture method, etc., so as to improve the bone regeneration and repair effect of biomaterials.", "page_width": 1191, "page_height": 1565, "role": "body_paragraph", "role_confidence": 0.6, "evidence": ["default body_paragraph for text label"], "seed_role": "body_paragraph", "seed_confidence": 0.6, "seed_evidence": ["default body_paragraph for text label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 6, "page": 14, "raw_label": "text", "text": "The preparation method affects the mechanical properties, thermal conductivity, heat resistance, and corrosion resistance of composite materials. For example, different preparation methods can control the distribution, morphology, and size of each component in composite materials, thereby affecting the mechanical properties of composite materials. In addition, the preparation method can also affect the interfacial bonding strength between the components in composite materials, thereby affecting the heat resistance and corrosion resistance of composite materials. In summary, the preparation method of composite materials has an important influence on their properties. Through the development of new technical systems, the innovation and development of biological materials can be promoted, and their performance and effect can be improved. The new technology system can include new material synthesis method, new surface modification technology, new cell culture method, etc., so as to improve the bone regeneration and repair effect of biomaterials.", "bbox": [89, 1244, 583, 1444], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "The preparation method affects the mechanical properties, thermal conductivity, heat resistance, and corrosion resistance of composite materials. For example, different preparation methods can control the distribution, morphology, and size of each component in composite materials, thereby affecting the mechanical properties of composite materials. In addition, the preparation method can also affect the interfacial bonding strength between the components in composite materials, thereby affecting the heat resistance and corrosion resistance of composite materials. In summary, the preparation method of composite materials has an important influence on their properties. Through the development of new technical systems, the innovation and development of biological materials can be promoted, and their performance and effect can be improved. The new technology system can include new material synthesis method, new surface modification technology, new cell culture method, etc., so as to improve the bone regeneration and repair effect of biomaterials."}, "layout_signature": {"width": 494, "width_bucket": 500, "height": 200, "left": 89, "top": 1244, "right": 583, "bottom": 1444, "x_center": 336.0, "x_center_bucket": 325, "y_center": 1344.0, "x_ratio": 0.2821, "y_ratio": 0.8588, "width_ratio": 0.4148, "height_ratio": 0.1278, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaPro-Regular", "bold": false, "italic": true, "span_count": 69}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_140", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 14, "block_id": 7, "raw_label": "text", "raw_order": 5, "bbox": [600, 149, 1093, 326], "text": "", "page_width": 1191, "page_height": 1565, "role": "ocr_text_missing", "role_confidence": 0.8, "evidence": ["ocr detected text region (raw_label=text) but no text extracted; no pdf backfill available"], "seed_role": "ocr_text_missing", "seed_confidence": 0.8, "seed_evidence": ["ocr detected text region (raw_label=text) but no text extracted; no pdf backfill available"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 7, "page": 14, "raw_label": "text", "text": "", "bbox": [600, 149, 1093, 326], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "empty", "raw_marker": null, "number": null, "kind": null, "normalized_text": ""}, "layout_signature": {"width": 493, "width_bucket": 500, "height": 177, "left": 600, "top": 149, "right": 1093, "bottom": 326, "x_center": 846.5, "x_center_bucket": 850, "y_center": 237.5, "x_ratio": 0.7107, "y_ratio": 0.1518, "width_ratio": 0.4139, "height_ratio": 0.1131, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaPro-Regular", "bold": false, "italic": true, "span_count": 26}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": "pdf_text_layer_fallback_rejected", "_ocr_raw_status": "missing_text_rejected", "_ocr_raw_error_type": "backfill_overlaps_existing_text_block", "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "_needs_pdf_fallback": true, "reading_band_id": "band_139", "display_cluster_candidate_id": "disp_27_0", "layout_region": "display_zone", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 14, "block_id": 8, "raw_label": "paragraph_title", "raw_order": 6, "bbox": [601, 360, 1003, 435], "text": "3. 3D printing Scaffolds and External Stimuli-Responsive Biomaterials for Bone Therapeutics and Regeneration", "page_width": 1191, "page_height": 1565, "role": "section_heading", "role_confidence": 0.85, "evidence": ["paragraph_title label with numbering: 3. 3D printing Scaffolds and External Stimuli-Responsive Bio"], "seed_role": "section_heading", "seed_confidence": 0.85, "seed_evidence": ["paragraph_title label with numbering: 3. 3D printing Scaffolds and External Stimuli-Responsive Bio"], "span_metadata": [{"size": 11.456999778747559, "font": "ScalaSansPro-Bold", "flags": 20, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 11.456999778747559, "font": "ScalaSansPro-Bold", "flags": 20, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 11.456999778747559, "font": "ScalaSansPro-Bold", "flags": 20, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 8, "page": 14, "raw_label": "paragraph_title", "text": "3. 3D printing Scaffolds and External Stimuli-Responsive Biomaterials for Bone Therapeutics and Regeneration", "bbox": [601, 360, 1003, 435], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_dot", "raw_marker": "3.", "number": 3, "kind": "reference", "normalized_text": "3. 3D printing Scaffolds and External Stimuli-Responsive Biomaterials for Bone Therapeutics and Regeneration"}, "layout_signature": {"width": 402, "width_bucket": 400, "height": 75, "left": 601, "top": 360, "right": 1003, "bottom": 435, "x_center": 802.0, "x_center_bucket": 800, "y_center": 397.5, "x_ratio": 0.6734, "y_ratio": 0.254, "width_ratio": 0.3375, "height_ratio": 0.0479, "line_count": 1}, "span_signature": {"font_size": 11.46, "font_size_median": 11.46, "font_size_bucket": 11.5, "font_family_norm": "ScalaSansPro-Bold", "bold": true, "italic": true, "span_count": 3}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_140", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "accepted_heading", "role_evidence": ["heading verified by heading artifact"]}
+{"paper_id": "2HEUD5P9", "page": 14, "block_id": 9, "raw_label": "text", "raw_order": 7, "bbox": [599, 447, 1093, 801], "text": "Through the development of new technical systems, the innovation and development of biological materials can be promoted, and their performance and effect can be improved. The new technology system can include new material synthesis method, new surface modification technology, new cell culture method, etc., so as to improve the bone regeneration and repair effect of biomaterials. 3D printing and external stimuli-responsive technology system can improve the therapeutic effect of biomaterials promoting bone regeneration and repair. Through the introduction of new technologies and methods, the biocompatibility, bioactivity and degradation performance of the materials can be improved, so as to enhance the bone regeneration and repair ability of the materials. The development of new technology systems can also provide more precise and customized treatment programs for different bone injuries or diseases, to achieve personalized bone regeneration and repair.", "page_width": 1191, "page_height": 1565, "role": "body_paragraph", "role_confidence": 0.6, "evidence": ["default body_paragraph for text label"], "seed_role": "body_paragraph", "seed_confidence": 0.6, "seed_evidence": ["default body_paragraph for text label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 9, "page": 14, "raw_label": "text", "text": "Through the development of new technical systems, the innovation and development of biological materials can be promoted, and their performance and effect can be improved. The new technology system can include new material synthesis method, new surface modification technology, new cell culture method, etc., so as to improve the bone regeneration and repair effect of biomaterials. 3D printing and external stimuli-responsive technology system can improve the therapeutic effect of biomaterials promoting bone regeneration and repair. Through the introduction of new technologies and methods, the biocompatibility, bioactivity and degradation performance of the materials can be improved, so as to enhance the bone regeneration and repair ability of the materials. The development of new technology systems can also provide more precise and customized treatment programs for different bone injuries or diseases, to achieve personalized bone regeneration and repair.", "bbox": [599, 447, 1093, 801], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "Through the development of new technical systems, the innovation and development of biological materials can be promoted, and their performance and effect can be improved. The new technology system can include new material synthesis method, new surface modification technology, new cell culture method, etc., so as to improve the bone regeneration and repair effect of biomaterials. 3D printing and external stimuli-responsive technology system can improve the therapeutic effect of biomaterials promoting bone regeneration and repair. Through the introduction of new technologies and methods, the biocompatibility, bioactivity and degradation performance of the materials can be improved, so as to enhance the bone regeneration and repair ability of the materials. The development of new technology systems can also provide more precise and customized treatment programs for different bone injuries or diseases, to achieve personalized bone regeneration and repair."}, "layout_signature": {"width": 494, "width_bucket": 500, "height": 354, "left": 599, "top": 447, "right": 1093, "bottom": 801, "x_center": 846.0, "x_center_bucket": 850, "y_center": 624.0, "x_ratio": 0.7103, "y_ratio": 0.3987, "width_ratio": 0.4148, "height_ratio": 0.2262, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaPro-Regular", "bold": false, "italic": true, "span_count": 58}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_138", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 14, "block_id": 10, "raw_label": "paragraph_title", "raw_order": 8, "bbox": [601, 835, 1029, 859], "text": "3.1. 3D Printing Technology for Bone Tissue Engineering", "page_width": 1191, "page_height": 1565, "role": "subsection_heading", "role_confidence": 0.85, "evidence": ["paragraph_title label with numbering: 3.1. 3D Printing Technology for Bone Tissue Engineering"], "seed_role": "subsection_heading", "seed_confidence": 0.85, "seed_evidence": ["paragraph_title label with numbering: 3.1. 3D Printing Technology for Bone Tissue Engineering"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaSansPro-Bold", "flags": 20, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 10, "page": 14, "raw_label": "paragraph_title", "text": "3.1. 3D Printing Technology for Bone Tissue Engineering", "bbox": [601, 835, 1029, 859], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "3.1. 3D Printing Technology for Bone Tissue Engineering"}, "layout_signature": {"width": 428, "width_bucket": 425, "height": 24, "left": 601, "top": 835, "right": 1029, "bottom": 859, "x_center": 815.0, "x_center_bucket": 825, "y_center": 847.0, "x_ratio": 0.6843, "y_ratio": 0.5412, "width_ratio": 0.3594, "height_ratio": 0.0153, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaSansPro-Bold", "bold": true, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_141", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "hard", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "accepted_heading", "role_evidence": ["heading verified by heading artifact"]}
+{"paper_id": "2HEUD5P9", "page": 14, "block_id": 11, "raw_label": "text", "raw_order": 9, "bbox": [600, 879, 1093, 1165], "text": "Developing 3D printing scaffolds have been used successfully to repair bone defects while effectively accelerating bone regeneration. Composite 3D printing scaffolds possess favorable characteristics and improved bioactivity when groups of materials are used together. The 3D scaffolds should be highly porous with an interconnected architecture for the migration of cells and nutrients. The surface of 3D scaffolds should also be optimized to promote cell proliferation, adhesion, and differentiation. However, the optimum manufacture protocol of 3D scaffold that can satisfy all the technical demands remains challenging. For instance, as the porosity of 3D scaffold is enhanced to promote cell migration and nutrient diffusion, mechanical properties would be decreased.", "page_width": 1191, "page_height": 1565, "role": "body_paragraph", "role_confidence": 0.6, "evidence": ["default body_paragraph for text label"], "seed_role": "body_paragraph", "seed_confidence": 0.6, "seed_evidence": ["default body_paragraph for text label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 11, "page": 14, "raw_label": "text", "text": "Developing 3D printing scaffolds have been used successfully to repair bone defects while effectively accelerating bone regeneration. Composite 3D printing scaffolds possess favorable characteristics and improved bioactivity when groups of materials are used together. The 3D scaffolds should be highly porous with an interconnected architecture for the migration of cells and nutrients. The surface of 3D scaffolds should also be optimized to promote cell proliferation, adhesion, and differentiation. However, the optimum manufacture protocol of 3D scaffold that can satisfy all the technical demands remains challenging. For instance, as the porosity of 3D scaffold is enhanced to promote cell migration and nutrient diffusion, mechanical properties would be decreased.", "bbox": [600, 879, 1093, 1165], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "Developing 3D printing scaffolds have been used successfully to repair bone defects while effectively accelerating bone regeneration. Composite 3D printing scaffolds possess favorable characteristics and improved bioactivity when groups of materials are used together. The 3D scaffolds should be highly porous with an interconnected architecture for the migration of cells and nutrients. The surface of 3D scaffolds should also be optimized to promote cell proliferation, adhesion, and differentiation. However, the optimum manufacture protocol of 3D scaffold that can satisfy all the technical demands remains challenging. For instance, as the porosity of 3D scaffold is enhanced to promote cell migration and nutrient diffusion, mechanical properties would be decreased."}, "layout_signature": {"width": 493, "width_bucket": 500, "height": 286, "left": 600, "top": 879, "right": 1093, "bottom": 1165, "x_center": 846.5, "x_center_bucket": 850, "y_center": 1022.0, "x_ratio": 0.7107, "y_ratio": 0.653, "width_ratio": 0.4139, "height_ratio": 0.1827, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaPro-Regular", "bold": false, "italic": true, "span_count": 95}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_142", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 14, "block_id": 12, "raw_label": "paragraph_title", "raw_order": 10, "bbox": [602, 1202, 908, 1225], "text": "3.1.1. Advances in 3D Printing Technology", "page_width": 1191, "page_height": 1565, "role": "sub_subsection_heading", "role_confidence": 0.85, "evidence": ["paragraph_title label with numbering: 3.1.1. Advances in 3D Printing Technology"], "seed_role": "sub_subsection_heading", "seed_confidence": 0.85, "seed_evidence": ["paragraph_title label with numbering: 3.1.1. Advances in 3D Printing Technology"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaSansPro-Italic", "flags": 6, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 12, "page": 14, "raw_label": "paragraph_title", "text": "3.1.1. Advances in 3D Printing Technology", "bbox": [602, 1202, 908, 1225], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "heading_numbered", "raw_marker": "3.1.1", "number": "3.1.1", "kind": "heading", "normalized_text": "3.1.1. Advances in 3D Printing Technology"}, "layout_signature": {"width": 306, "width_bucket": 300, "height": 23, "left": 602, "top": 1202, "right": 908, "bottom": 1225, "x_center": 755.0, "x_center_bucket": 750, "y_center": 1213.5, "x_ratio": 0.6339, "y_ratio": 0.7754, "width_ratio": 0.2569, "height_ratio": 0.0147, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaSansPro-Italic", "bold": false, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_142", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 14, "block_id": 13, "raw_label": "text", "raw_order": 11, "bbox": [598, 1245, 1093, 1445], "text": "A large variety of conventional techniques, such as gas foaming, freeze-drying, solvent casting, phase separation, and electrospinning, have been used to manufacture scaffolds for various tissues based on preclinical trials; however, the pore size, geometry, and interconnectivity of the scaffolds fabricated using these techniques cannot be precisely controlled. Alternatively, 3D printing is emerging as an innovative manufacturing approach for improving the production of bone scaffolds. SF solution of 30 wt% was extracted from cocoons and combined with", "page_width": 1191, "page_height": 1565, "role": "body_paragraph", "role_confidence": 0.6, "evidence": ["default body_paragraph for text label"], "seed_role": "body_paragraph", "seed_confidence": 0.6, "seed_evidence": ["default body_paragraph for text label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 13, "page": 14, "raw_label": "text", "text": "A large variety of conventional techniques, such as gas foaming, freeze-drying, solvent casting, phase separation, and electrospinning, have been used to manufacture scaffolds for various tissues based on preclinical trials; however, the pore size, geometry, and interconnectivity of the scaffolds fabricated using these techniques cannot be precisely controlled. Alternatively, 3D printing is emerging as an innovative manufacturing approach for improving the production of bone scaffolds. SF solution of 30 wt% was extracted from cocoons and combined with", "bbox": [598, 1245, 1093, 1445], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "A large variety of conventional techniques, such as gas foaming, freeze-drying, solvent casting, phase separation, and electrospinning, have been used to manufacture scaffolds for various tissues based on preclinical trials; however, the pore size, geometry, and interconnectivity of the scaffolds fabricated using these techniques cannot be precisely controlled. Alternatively, 3D printing is emerging as an innovative manufacturing approach for improving the production of bone scaffolds. SF solution of 30 wt% was extracted from cocoons and combined with"}, "layout_signature": {"width": 495, "width_bucket": 500, "height": 200, "left": 598, "top": 1245, "right": 1093, "bottom": 1445, "x_center": 845.5, "x_center_bucket": 850, "y_center": 1345.0, "x_ratio": 0.7099, "y_ratio": 0.8594, "width_ratio": 0.4156, "height_ratio": 0.1278, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaPro-Regular", "bold": false, "italic": true, "span_count": 123}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_136", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 14, "block_id": 14, "raw_label": "footer", "raw_order": null, "bbox": [94, 1487, 283, 1505], "text": "Small Methods 2024, 8, 2301283", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["footer label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["footer label"], "span_metadata": [{"size": 6.973800182342529, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 14, "page": 14, "raw_label": "footer", "text": "Small Methods 2024, 8, 2301283", "bbox": [94, 1487, 283, 1505], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "Small Methods 2024, 8, 2301283"}, "layout_signature": {"width": 189, "width_bucket": 200, "height": 18, "left": 94, "top": 1487, "right": 283, "bottom": 1505, "x_center": 188.5, "x_center_bucket": 200, "y_center": 1496.0, "x_ratio": 0.1583, "y_ratio": 0.9559, "width_ratio": 0.1587, "height_ratio": 0.0115, "line_count": 1}, "span_signature": {"font_size": 6.97, "font_size_median": 6.97, "font_size_bucket": 7.0, "font_family_norm": "ScalaSansPro-Italic", "bold": true, "italic": true, "span_count": 5}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_136", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 14, "block_id": 15, "raw_label": "footer", "raw_order": null, "bbox": [520, 1484, 663, 1507], "text": "2301283 (14 of 27)", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["footer label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["footer label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaSansPro-Bold", "flags": 20, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 15, "page": 14, "raw_label": "footer", "text": "2301283 (14 of 27)", "bbox": [520, 1484, 663, 1507], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_dot", "raw_marker": "2301283", "number": 2301283, "kind": "reference", "normalized_text": "2301283 (14 of 27)"}, "layout_signature": {"width": 143, "width_bucket": 150, "height": 23, "left": 520, "top": 1484, "right": 663, "bottom": 1507, "x_center": 591.5, "x_center_bucket": 600, "y_center": 1495.5, "x_ratio": 0.4966, "y_ratio": 0.9556, "width_ratio": 0.1201, "height_ratio": 0.0147, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaSansPro-Bold", "bold": true, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "reference_like", "style_family_authority": "reference_family_anchor", "reading_band_id": "band_136", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 14, "block_id": 16, "raw_label": "footer", "raw_order": null, "bbox": [931, 1486, 1090, 1506], "text": "© 2024 Wiley-VCH GmbH", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["footer label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["footer label"], "span_metadata": [{"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 16, "page": 14, "raw_label": "footer", "text": "© 2024 Wiley-VCH GmbH", "bbox": [931, 1486, 1090, 1506], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "© 2024 Wiley-VCH GmbH"}, "layout_signature": {"width": 159, "width_bucket": 150, "height": 20, "left": 931, "top": 1486, "right": 1090, "bottom": 1506, "x_center": 1010.5, "x_center_bucket": 1000, "y_center": 1496.0, "x_ratio": 0.8484, "y_ratio": 0.9559, "width_ratio": 0.1335, "height_ratio": 0.0128, "line_count": 1}, "span_signature": {"font_size": 6.97, "font_size_median": 6.97, "font_size_bucket": 7.0, "font_family_norm": "ScalaSansPro-Regular", "bold": false, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_136", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 14, "block_id": 17, "raw_label": "aside_text", "raw_order": null, "bbox": [1154, 30, 1171, 1534], "text": "23699608, 2024, 8, Downloaded from https://onlinelibrary.wiley.com/doi/10.1002/smkt.202301283 by Shandong University Library, Wiley Online Library on [18/02/2026]. See the Terms and Conditions (https://onlinelibrary.wiley.com/terms-and-conditions) on Wiley Online Library for rules of use; OA articles are governed by the applicable Creative Commons License.", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.95, "evidence": ["margin-band narrow/tall geometry; treated as noise"], "seed_role": "noise", "seed_confidence": 0.95, "seed_evidence": ["margin-band narrow/tall geometry; treated as noise"], "span_metadata": [{"size": 5.03000020980835, "font": "Times-Roman", "flags": 4, "color": 0, "dir": [0.0, 1.0], "wmode": 0}], "raw_observation": {"block_id": 17, "page": 14, "raw_label": "aside_text", "text": "23699608, 2024, 8, Downloaded from https://onlinelibrary.wiley.com/doi/10.1002/smkt.202301283 by Shandong University Library, Wiley Online Library on [18/02/2026]. See the Terms and Conditions (https://onlinelibrary.wiley.com/terms-and-conditions) on Wiley Online Library for rules of use; OA articles are governed by the applicable Creative Commons License.", "bbox": [1154, 30, 1171, 1534], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "23699608, 2024, 8, Downloaded from https://onlinelibrary.wiley.com/doi/10.1002/smkt.202301283 by Shandong University Library, Wiley Online Library on [18/02/2026]. See the Terms and Conditions (https://onlinelibrary.wiley.com/terms-and-conditions) on Wiley Online Library for rules of use; OA articles are governed by the applicable Creative Commons License."}, "layout_signature": {"width": 17, "width_bucket": 25, "height": 1504, "left": 1154, "top": 30, "right": 1171, "bottom": 1534, "x_center": 1162.5, "x_center_bucket": 1150, "y_center": 782.0, "x_ratio": 0.9761, "y_ratio": 0.4997, "width_ratio": 0.0143, "height_ratio": 0.961, "line_count": 1}, "span_signature": {"font_size": 5.03, "font_size_median": 5.03, "font_size_bucket": 5.0, "font_family_norm": "Times-Roman", "bold": false, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_family_anchor", "reading_band_id": "band_136", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 15, "block_id": 0, "raw_label": "header", "raw_order": null, "bbox": [98, 45, 345, 117], "text": "ADVANCED\nSCIENCE NEWS\nwww.advancedsciencenews.com", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["header label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["header label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaSansPro-Bold", "flags": 20, "color": 255, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 0, "page": 15, "raw_label": "header", "text": "ADVANCED\nSCIENCE NEWS\nwww.advancedsciencenews.com", "bbox": [98, 45, 345, 117], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "ADVANCED\nSCIENCE NEWS\nwww.advancedsciencenews.com"}, "layout_signature": {"width": 247, "width_bucket": 250, "height": 72, "left": 98, "top": 45, "right": 345, "bottom": 117, "x_center": 221.5, "x_center_bucket": 225, "y_center": 81.0, "x_ratio": 0.186, "y_ratio": 0.0518, "width_ratio": 0.2074, "height_ratio": 0.046, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaSansPro-Bold", "bold": true, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 15, "block_id": 1, "raw_label": "header", "raw_order": null, "bbox": [900, 36, 1097, 117], "text": "small methods\nwww.small-methods.com", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["header label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["header label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaSansPro-Bold", "flags": 20, "color": 255, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 1, "page": 15, "raw_label": "header", "text": "small methods\nwww.small-methods.com", "bbox": [900, 36, 1097, 117], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "small methods\nwww.small-methods.com"}, "layout_signature": {"width": 197, "width_bucket": 200, "height": 81, "left": 900, "top": 36, "right": 1097, "bottom": 117, "x_center": 998.5, "x_center_bucket": 1000, "y_center": 76.5, "x_ratio": 0.8384, "y_ratio": 0.0489, "width_ratio": 0.1654, "height_ratio": 0.0518, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaSansPro-Bold", "bold": true, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_142", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 15, "block_id": 2, "raw_label": "figure_title", "raw_order": null, "bbox": [109, 152, 144, 180], "text": "(A)", "page_width": 1191, "page_height": 1565, "role": "figure_inner_text", "role_confidence": 0.9, "evidence": ["panel label / figure inner text: (A)"], "seed_role": "figure_inner_text", "seed_confidence": 0.9, "seed_evidence": ["panel label / figure inner text: (A)"], "span_metadata": null, "raw_observation": {"block_id": 2, "page": 15, "raw_label": "figure_title", "text": "(A)", "bbox": [109, 152, 144, 180], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "panel_label", "raw_marker": "(A)", "number": null, "kind": "panel_label", "normalized_text": "(A)"}, "layout_signature": {"width": 35, "width_bucket": 25, "height": 28, "left": 109, "top": 152, "right": 144, "bottom": 180, "x_center": 126.5, "x_center_bucket": 125, "y_center": 166.0, "x_ratio": 0.1062, "y_ratio": 0.1061, "width_ratio": 0.0294, "height_ratio": 0.0179, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "display_zone", "style_family": "legend_like", "style_family_authority": "figure_marker", "reading_band_id": "band_142", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 15, "block_id": 3, "raw_label": "image", "raw_order": null, "bbox": [109, 162, 583, 282], "text": "", "page_width": 1191, "page_height": 1565, "role": "figure_asset", "role_confidence": 0.85, "evidence": ["media label: image"], "seed_role": "media_asset", "seed_confidence": 0.85, "seed_evidence": ["media label: image"], "span_metadata": null, "raw_observation": {"block_id": 3, "page": 15, "raw_label": "image", "text": "", "bbox": [109, 162, 583, 282], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "empty", "raw_marker": null, "number": null, "kind": null, "normalized_text": ""}, "layout_signature": {"width": 474, "width_bucket": 475, "height": 120, "left": 109, "top": 162, "right": 583, "bottom": 282, "x_center": 346.0, "x_center_bucket": 350, "y_center": 222.0, "x_ratio": 0.2905, "y_ratio": 0.1419, "width_ratio": 0.398, "height_ratio": 0.0767, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_139", "display_cluster_candidate_id": "disp_27_0", "layout_region": "display_zone", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"], "asset_family_hint": "figure_like", "asset_family_confidence": 0.7, "asset_family_evidence": ["raw_label:image"]}
+{"paper_id": "2HEUD5P9", "page": 15, "block_id": 4, "raw_label": "figure_title", "raw_order": null, "bbox": [109, 278, 142, 306], "text": "(B)", "page_width": 1191, "page_height": 1565, "role": "figure_inner_text", "role_confidence": 0.9, "evidence": ["panel label / figure inner text: (B)"], "seed_role": "figure_inner_text", "seed_confidence": 0.9, "seed_evidence": ["panel label / figure inner text: (B)"], "span_metadata": null, "raw_observation": {"block_id": 4, "page": 15, "raw_label": "figure_title", "text": "(B)", "bbox": [109, 278, 142, 306], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "panel_label", "raw_marker": "(B)", "number": null, "kind": "panel_label", "normalized_text": "(B)"}, "layout_signature": {"width": 33, "width_bucket": 25, "height": 28, "left": 109, "top": 278, "right": 142, "bottom": 306, "x_center": 125.5, "x_center_bucket": 125, "y_center": 292.0, "x_ratio": 0.1054, "y_ratio": 0.1866, "width_ratio": 0.0277, "height_ratio": 0.0179, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "display_zone", "style_family": "legend_like", "style_family_authority": "figure_marker", "reading_band_id": "band_140", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 15, "block_id": 5, "raw_label": "chart", "raw_order": null, "bbox": [433, 168, 580, 283], "text": "", "page_width": 1191, "page_height": 1565, "role": "figure_asset", "role_confidence": 0.85, "evidence": ["media label: chart"], "seed_role": "media_asset", "seed_confidence": 0.85, "seed_evidence": ["media label: chart"], "span_metadata": null, "raw_observation": {"block_id": 5, "page": 15, "raw_label": "chart", "text": "", "bbox": [433, 168, 580, 283], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "empty", "raw_marker": null, "number": null, "kind": null, "normalized_text": ""}, "layout_signature": {"width": 147, "width_bucket": 150, "height": 115, "left": 433, "top": 168, "right": 580, "bottom": 283, "x_center": 506.5, "x_center_bucket": 500, "y_center": 225.5, "x_ratio": 0.4253, "y_ratio": 0.1441, "width_ratio": 0.1234, "height_ratio": 0.0735, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_139", "display_cluster_candidate_id": "disp_27_0", "layout_region": "display_zone", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"], "asset_family_hint": "figure_like", "asset_family_confidence": 0.7, "asset_family_evidence": ["raw_label:chart"]}
+{"paper_id": "2HEUD5P9", "page": 15, "block_id": 6, "raw_label": "image", "raw_order": null, "bbox": [152, 286, 275, 400], "text": "", "page_width": 1191, "page_height": 1565, "role": "figure_asset", "role_confidence": 0.85, "evidence": ["media label: image"], "seed_role": "media_asset", "seed_confidence": 0.85, "seed_evidence": ["media label: image"], "span_metadata": null, "raw_observation": {"block_id": 6, "page": 15, "raw_label": "image", "text": "", "bbox": [152, 286, 275, 400], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "empty", "raw_marker": null, "number": null, "kind": null, "normalized_text": ""}, "layout_signature": {"width": 123, "width_bucket": 125, "height": 114, "left": 152, "top": 286, "right": 275, "bottom": 400, "x_center": 213.5, "x_center_bucket": 225, "y_center": 343.0, "x_ratio": 0.1793, "y_ratio": 0.2192, "width_ratio": 0.1033, "height_ratio": 0.0728, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_140", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"], "asset_family_hint": "figure_like", "asset_family_confidence": 0.7, "asset_family_evidence": ["raw_label:image"]}
+{"paper_id": "2HEUD5P9", "page": 15, "block_id": 7, "raw_label": "chart", "raw_order": null, "bbox": [431, 292, 580, 403], "text": "", "page_width": 1191, "page_height": 1565, "role": "figure_asset", "role_confidence": 0.85, "evidence": ["media label: chart"], "seed_role": "media_asset", "seed_confidence": 0.85, "seed_evidence": ["media label: chart"], "span_metadata": null, "raw_observation": {"block_id": 7, "page": 15, "raw_label": "chart", "text": "", "bbox": [431, 292, 580, 403], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "empty", "raw_marker": null, "number": null, "kind": null, "normalized_text": ""}, "layout_signature": {"width": 149, "width_bucket": 150, "height": 111, "left": 431, "top": 292, "right": 580, "bottom": 403, "x_center": 505.5, "x_center_bucket": 500, "y_center": 347.5, "x_ratio": 0.4244, "y_ratio": 0.222, "width_ratio": 0.1251, "height_ratio": 0.0709, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_139", "display_cluster_candidate_id": "disp_27_0", "layout_region": "display_zone", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"], "asset_family_hint": "figure_like", "asset_family_confidence": 0.7, "asset_family_evidence": ["raw_label:chart"]}
+{"paper_id": "2HEUD5P9", "page": 15, "block_id": 8, "raw_label": "figure_title", "raw_order": null, "bbox": [634, 181, 658, 202], "text": "(a)", "page_width": 1191, "page_height": 1565, "role": "figure_inner_text", "role_confidence": 0.9, "evidence": ["panel label / figure inner text: (a)"], "seed_role": "figure_inner_text", "seed_confidence": 0.9, "seed_evidence": ["panel label / figure inner text: (a)"], "span_metadata": null, "raw_observation": {"block_id": 8, "page": 15, "raw_label": "figure_title", "text": "(a)", "bbox": [634, 181, 658, 202], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "panel_label", "raw_marker": "(a)", "number": null, "kind": "panel_label", "normalized_text": "(a)"}, "layout_signature": {"width": 24, "width_bucket": 25, "height": 21, "left": 634, "top": 181, "right": 658, "bottom": 202, "x_center": 646.0, "x_center_bucket": 650, "y_center": 191.5, "x_ratio": 0.5424, "y_ratio": 0.1224, "width_ratio": 0.0202, "height_ratio": 0.0134, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "display_zone", "style_family": "legend_like", "style_family_authority": "figure_marker", "reading_band_id": "band_140", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 15, "block_id": 9, "raw_label": "figure_title", "raw_order": null, "bbox": [594, 152, 628, 179], "text": "(D)", "page_width": 1191, "page_height": 1565, "role": "figure_inner_text", "role_confidence": 0.9, "evidence": ["panel label / figure inner text: (D)"], "seed_role": "figure_inner_text", "seed_confidence": 0.9, "seed_evidence": ["panel label / figure inner text: (D)"], "span_metadata": null, "raw_observation": {"block_id": 9, "page": 15, "raw_label": "figure_title", "text": "(D)", "bbox": [594, 152, 628, 179], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "panel_label", "raw_marker": "(D)", "number": null, "kind": "panel_label", "normalized_text": "(D)"}, "layout_signature": {"width": 34, "width_bucket": 25, "height": 27, "left": 594, "top": 152, "right": 628, "bottom": 179, "x_center": 611.0, "x_center_bucket": 600, "y_center": 165.5, "x_ratio": 0.513, "y_ratio": 0.1058, "width_ratio": 0.0285, "height_ratio": 0.0173, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "display_zone", "style_family": "legend_like", "style_family_authority": "figure_marker", "reading_band_id": "band_138", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 15, "block_id": 10, "raw_label": "figure_title", "raw_order": null, "bbox": [108, 400, 143, 428], "text": "(C)", "page_width": 1191, "page_height": 1565, "role": "figure_inner_text", "role_confidence": 0.9, "evidence": ["panel label / figure inner text: (C)"], "seed_role": "figure_inner_text", "seed_confidence": 0.9, "seed_evidence": ["panel label / figure inner text: (C)"], "span_metadata": null, "raw_observation": {"block_id": 10, "page": 15, "raw_label": "figure_title", "text": "(C)", "bbox": [108, 400, 143, 428], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "panel_label", "raw_marker": "(C)", "number": null, "kind": "panel_label", "normalized_text": "(C)"}, "layout_signature": {"width": 35, "width_bucket": 25, "height": 28, "left": 108, "top": 400, "right": 143, "bottom": 428, "x_center": 125.5, "x_center_bucket": 125, "y_center": 414.0, "x_ratio": 0.1054, "y_ratio": 0.2645, "width_ratio": 0.0294, "height_ratio": 0.0179, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "display_zone", "style_family": "legend_like", "style_family_authority": "figure_marker", "reading_band_id": "band_141", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "hard", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 15, "block_id": 11, "raw_label": "chart", "raw_order": null, "bbox": [161, 416, 362, 561], "text": "", "page_width": 1191, "page_height": 1565, "role": "figure_asset", "role_confidence": 0.85, "evidence": ["media label: chart"], "seed_role": "media_asset", "seed_confidence": 0.85, "seed_evidence": ["media label: chart"], "span_metadata": null, "raw_observation": {"block_id": 11, "page": 15, "raw_label": "chart", "text": "", "bbox": [161, 416, 362, 561], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "empty", "raw_marker": null, "number": null, "kind": null, "normalized_text": ""}, "layout_signature": {"width": 201, "width_bucket": 200, "height": 145, "left": 161, "top": 416, "right": 362, "bottom": 561, "x_center": 261.5, "x_center_bucket": 250, "y_center": 488.5, "x_ratio": 0.2196, "y_ratio": 0.3121, "width_ratio": 0.1688, "height_ratio": 0.0927, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_142", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"], "asset_family_hint": "figure_like", "asset_family_confidence": 0.7, "asset_family_evidence": ["raw_label:chart"]}
+{"paper_id": "2HEUD5P9", "page": 15, "block_id": 12, "raw_label": "chart", "raw_order": null, "bbox": [381, 420, 577, 561], "text": "", "page_width": 1191, "page_height": 1565, "role": "figure_asset", "role_confidence": 0.85, "evidence": ["media label: chart"], "seed_role": "media_asset", "seed_confidence": 0.85, "seed_evidence": ["media label: chart"], "span_metadata": null, "raw_observation": {"block_id": 12, "page": 15, "raw_label": "chart", "text": "", "bbox": [381, 420, 577, 561], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "empty", "raw_marker": null, "number": null, "kind": null, "normalized_text": ""}, "layout_signature": {"width": 196, "width_bucket": 200, "height": 141, "left": 381, "top": 420, "right": 577, "bottom": 561, "x_center": 479.0, "x_center_bucket": 475, "y_center": 490.5, "x_ratio": 0.4022, "y_ratio": 0.3134, "width_ratio": 0.1646, "height_ratio": 0.0901, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_142", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"], "asset_family_hint": "figure_like", "asset_family_confidence": 0.7, "asset_family_evidence": ["raw_label:chart"]}
+{"paper_id": "2HEUD5P9", "page": 15, "block_id": 13, "raw_label": "image", "raw_order": null, "bbox": [603, 155, 1084, 524], "text": "", "page_width": 1191, "page_height": 1565, "role": "figure_asset", "role_confidence": 0.85, "evidence": ["media label: image"], "seed_role": "media_asset", "seed_confidence": 0.85, "seed_evidence": ["media label: image"], "span_metadata": null, "raw_observation": {"block_id": 13, "page": 15, "raw_label": "image", "text": "", "bbox": [603, 155, 1084, 524], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "empty", "raw_marker": null, "number": null, "kind": null, "normalized_text": ""}, "layout_signature": {"width": 481, "width_bucket": 475, "height": 369, "left": 603, "top": 155, "right": 1084, "bottom": 524, "x_center": 843.5, "x_center_bucket": 850, "y_center": 339.5, "x_ratio": 0.7082, "y_ratio": 0.2169, "width_ratio": 0.4039, "height_ratio": 0.2358, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_136", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"], "asset_family_hint": "figure_like", "asset_family_confidence": 0.7, "asset_family_evidence": ["raw_label:image"]}
+{"paper_id": "2HEUD5P9", "page": 15, "block_id": 14, "raw_label": "chart", "raw_order": null, "bbox": [164, 570, 362, 716], "text": "", "page_width": 1191, "page_height": 1565, "role": "figure_asset", "role_confidence": 0.85, "evidence": ["media label: chart"], "seed_role": "media_asset", "seed_confidence": 0.85, "seed_evidence": ["media label: chart"], "span_metadata": null, "raw_observation": {"block_id": 14, "page": 15, "raw_label": "chart", "text": "", "bbox": [164, 570, 362, 716], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "empty", "raw_marker": null, "number": null, "kind": null, "normalized_text": ""}, "layout_signature": {"width": 198, "width_bucket": 200, "height": 146, "left": 164, "top": 570, "right": 362, "bottom": 716, "x_center": 263.0, "x_center_bucket": 275, "y_center": 643.0, "x_ratio": 0.2208, "y_ratio": 0.4109, "width_ratio": 0.1662, "height_ratio": 0.0933, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_136", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"], "asset_family_hint": "figure_like", "asset_family_confidence": 0.7, "asset_family_evidence": ["raw_label:chart"]}
+{"paper_id": "2HEUD5P9", "page": 15, "block_id": 15, "raw_label": "chart", "raw_order": null, "bbox": [381, 571, 580, 715], "text": "", "page_width": 1191, "page_height": 1565, "role": "figure_asset", "role_confidence": 0.85, "evidence": ["media label: chart"], "seed_role": "media_asset", "seed_confidence": 0.85, "seed_evidence": ["media label: chart"], "span_metadata": null, "raw_observation": {"block_id": 15, "page": 15, "raw_label": "chart", "text": "", "bbox": [381, 571, 580, 715], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "empty", "raw_marker": null, "number": null, "kind": null, "normalized_text": ""}, "layout_signature": {"width": 199, "width_bucket": 200, "height": 144, "left": 381, "top": 571, "right": 580, "bottom": 715, "x_center": 480.5, "x_center_bucket": 475, "y_center": 643.0, "x_ratio": 0.4034, "y_ratio": 0.4109, "width_ratio": 0.1671, "height_ratio": 0.092, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_136", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"], "asset_family_hint": "figure_like", "asset_family_confidence": 0.7, "asset_family_evidence": ["raw_label:chart"]}
+{"paper_id": "2HEUD5P9", "page": 15, "block_id": 16, "raw_label": "image", "raw_order": null, "bbox": [610, 565, 762, 685], "text": "", "page_width": 1191, "page_height": 1565, "role": "figure_asset", "role_confidence": 0.85, "evidence": ["media label: image"], "seed_role": "media_asset", "seed_confidence": 0.85, "seed_evidence": ["media label: image"], "span_metadata": null, "raw_observation": {"block_id": 16, "page": 15, "raw_label": "image", "text": "", "bbox": [610, 565, 762, 685], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "empty", "raw_marker": null, "number": null, "kind": null, "normalized_text": ""}, "layout_signature": {"width": 152, "width_bucket": 150, "height": 120, "left": 610, "top": 565, "right": 762, "bottom": 685, "x_center": 686.0, "x_center_bucket": 675, "y_center": 625.0, "x_ratio": 0.576, "y_ratio": 0.3994, "width_ratio": 0.1276, "height_ratio": 0.0767, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_136", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"], "asset_family_hint": "figure_like", "asset_family_confidence": 0.7, "asset_family_evidence": ["raw_label:image"]}
+{"paper_id": "2HEUD5P9", "page": 15, "block_id": 17, "raw_label": "image", "raw_order": null, "bbox": [765, 567, 928, 680], "text": "", "page_width": 1191, "page_height": 1565, "role": "figure_asset", "role_confidence": 0.85, "evidence": ["media label: image"], "seed_role": "media_asset", "seed_confidence": 0.85, "seed_evidence": ["media label: image"], "span_metadata": null, "raw_observation": {"block_id": 17, "page": 15, "raw_label": "image", "text": "", "bbox": [765, 567, 928, 680], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "empty", "raw_marker": null, "number": null, "kind": null, "normalized_text": ""}, "layout_signature": {"width": 163, "width_bucket": 175, "height": 113, "left": 765, "top": 567, "right": 928, "bottom": 680, "x_center": 846.5, "x_center_bucket": 850, "y_center": 623.5, "x_ratio": 0.7107, "y_ratio": 0.3984, "width_ratio": 0.1369, "height_ratio": 0.0722, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_136", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"], "asset_family_hint": "figure_like", "asset_family_confidence": 0.7, "asset_family_evidence": ["raw_label:image"]}
+{"paper_id": "2HEUD5P9", "page": 15, "block_id": 18, "raw_label": "image", "raw_order": null, "bbox": [933, 567, 1087, 678], "text": "", "page_width": 1191, "page_height": 1565, "role": "figure_asset", "role_confidence": 0.85, "evidence": ["media label: image"], "seed_role": "media_asset", "seed_confidence": 0.85, "seed_evidence": ["media label: image"], "span_metadata": null, "raw_observation": {"block_id": 18, "page": 15, "raw_label": "image", "text": "", "bbox": [933, 567, 1087, 678], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "empty", "raw_marker": null, "number": null, "kind": null, "normalized_text": ""}, "layout_signature": {"width": 154, "width_bucket": 150, "height": 111, "left": 933, "top": 567, "right": 1087, "bottom": 678, "x_center": 1010.0, "x_center_bucket": 1000, "y_center": 622.5, "x_ratio": 0.848, "y_ratio": 0.3978, "width_ratio": 0.1293, "height_ratio": 0.0709, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_136", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"], "asset_family_hint": "figure_like", "asset_family_confidence": 0.7, "asset_family_evidence": ["raw_label:image"]}
+{"paper_id": "2HEUD5P9", "page": 15, "block_id": 19, "raw_label": "figure_title", "raw_order": null, "bbox": [104, 725, 139, 754], "text": "(E)", "page_width": 1191, "page_height": 1565, "role": "figure_inner_text", "role_confidence": 0.9, "evidence": ["panel label / figure inner text: (E)"], "seed_role": "figure_inner_text", "seed_confidence": 0.9, "seed_evidence": ["panel label / figure inner text: (E)"], "span_metadata": null, "raw_observation": {"block_id": 19, "page": 15, "raw_label": "figure_title", "text": "(E)", "bbox": [104, 725, 139, 754], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "panel_label", "raw_marker": "(E)", "number": null, "kind": "panel_label", "normalized_text": "(E)"}, "layout_signature": {"width": 35, "width_bucket": 25, "height": 29, "left": 104, "top": 725, "right": 139, "bottom": 754, "x_center": 121.5, "x_center_bucket": 125, "y_center": 739.5, "x_ratio": 0.102, "y_ratio": 0.4725, "width_ratio": 0.0294, "height_ratio": 0.0185, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "display_zone", "style_family": "legend_like", "style_family_authority": "figure_marker", "reading_band_id": "band_136", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 15, "block_id": 20, "raw_label": "figure_title", "raw_order": null, "bbox": [475, 726, 510, 753], "text": "(G)", "page_width": 1191, "page_height": 1565, "role": "figure_inner_text", "role_confidence": 0.9, "evidence": ["panel label / figure inner text: (G)"], "seed_role": "figure_inner_text", "seed_confidence": 0.9, "seed_evidence": ["panel label / figure inner text: (G)"], "span_metadata": null, "raw_observation": {"block_id": 20, "page": 15, "raw_label": "figure_title", "text": "(G)", "bbox": [475, 726, 510, 753], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "panel_label", "raw_marker": "(G)", "number": null, "kind": "panel_label", "normalized_text": "(G)"}, "layout_signature": {"width": 35, "width_bucket": 25, "height": 27, "left": 475, "top": 726, "right": 510, "bottom": 753, "x_center": 492.5, "x_center_bucket": 500, "y_center": 739.5, "x_ratio": 0.4135, "y_ratio": 0.4725, "width_ratio": 0.0294, "height_ratio": 0.0173, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "display_zone", "style_family": "legend_like", "style_family_authority": "figure_marker", "reading_band_id": "band_136", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 15, "block_id": 21, "raw_label": "image", "raw_order": null, "bbox": [135, 750, 454, 912], "text": "", "page_width": 1191, "page_height": 1565, "role": "figure_asset", "role_confidence": 0.85, "evidence": ["media label: image"], "seed_role": "media_asset", "seed_confidence": 0.85, "seed_evidence": ["media label: image"], "span_metadata": null, "raw_observation": {"block_id": 21, "page": 15, "raw_label": "image", "text": "", "bbox": [135, 750, 454, 912], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "empty", "raw_marker": null, "number": null, "kind": null, "normalized_text": ""}, "layout_signature": {"width": 319, "width_bucket": 325, "height": 162, "left": 135, "top": 750, "right": 454, "bottom": 912, "x_center": 294.5, "x_center_bucket": 300, "y_center": 831.0, "x_ratio": 0.2473, "y_ratio": 0.531, "width_ratio": 0.2678, "height_ratio": 0.1035, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_133", "display_cluster_candidate_id": "disp_26_0", "layout_region": "display_zone", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"], "asset_family_hint": "figure_like", "asset_family_confidence": 0.7, "asset_family_evidence": ["raw_label:image"]}
+{"paper_id": "2HEUD5P9", "page": 15, "block_id": 22, "raw_label": "figure_title", "raw_order": null, "bbox": [105, 911, 136, 940], "text": "(F)", "page_width": 1191, "page_height": 1565, "role": "figure_inner_text", "role_confidence": 0.9, "evidence": ["panel label / figure inner text: (F)"], "seed_role": "figure_inner_text", "seed_confidence": 0.9, "seed_evidence": ["panel label / figure inner text: (F)"], "span_metadata": null, "raw_observation": {"block_id": 22, "page": 15, "raw_label": "figure_title", "text": "(F)", "bbox": [105, 911, 136, 940], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "panel_label", "raw_marker": "(F)", "number": null, "kind": "panel_label", "normalized_text": "(F)"}, "layout_signature": {"width": 31, "width_bucket": 25, "height": 29, "left": 105, "top": 911, "right": 136, "bottom": 940, "x_center": 120.5, "x_center_bucket": 125, "y_center": 925.5, "x_ratio": 0.1012, "y_ratio": 0.5914, "width_ratio": 0.026, "height_ratio": 0.0185, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "display_zone", "style_family": "legend_like", "style_family_authority": "figure_marker", "reading_band_id": "band_134", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 15, "block_id": 23, "raw_label": "image", "raw_order": null, "bbox": [130, 915, 459, 1078], "text": "", "page_width": 1191, "page_height": 1565, "role": "figure_asset", "role_confidence": 0.85, "evidence": ["media label: image"], "seed_role": "media_asset", "seed_confidence": 0.85, "seed_evidence": ["media label: image"], "span_metadata": null, "raw_observation": {"block_id": 23, "page": 15, "raw_label": "image", "text": "", "bbox": [130, 915, 459, 1078], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "empty", "raw_marker": null, "number": null, "kind": null, "normalized_text": ""}, "layout_signature": {"width": 329, "width_bucket": 325, "height": 163, "left": 130, "top": 915, "right": 459, "bottom": 1078, "x_center": 294.5, "x_center_bucket": 300, "y_center": 996.5, "x_ratio": 0.2473, "y_ratio": 0.6367, "width_ratio": 0.2762, "height_ratio": 0.1042, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_133", "display_cluster_candidate_id": "disp_26_0", "layout_region": "display_zone", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"], "asset_family_hint": "figure_like", "asset_family_confidence": 0.7, "asset_family_evidence": ["raw_label:image"]}
+{"paper_id": "2HEUD5P9", "page": 15, "block_id": 24, "raw_label": "image", "raw_order": null, "bbox": [486, 732, 1084, 1086], "text": "", "page_width": 1191, "page_height": 1565, "role": "figure_asset", "role_confidence": 0.85, "evidence": ["media label: image"], "seed_role": "media_asset", "seed_confidence": 0.85, "seed_evidence": ["media label: image"], "span_metadata": null, "raw_observation": {"block_id": 24, "page": 15, "raw_label": "image", "text": "", "bbox": [486, 732, 1084, 1086], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "empty", "raw_marker": null, "number": null, "kind": null, "normalized_text": ""}, "layout_signature": {"width": 598, "width_bucket": 600, "height": 354, "left": 486, "top": 732, "right": 1084, "bottom": 1086, "x_center": 785.0, "x_center_bucket": 775, "y_center": 909.0, "x_ratio": 0.6591, "y_ratio": 0.5808, "width_ratio": 0.5021, "height_ratio": 0.2262, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_134", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.0, "decision": "body", "evidence": []}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"], "asset_family_hint": "figure_like", "asset_family_confidence": 0.7, "asset_family_evidence": ["raw_label:image"]}
+{"paper_id": "2HEUD5P9", "page": 15, "block_id": 25, "raw_label": "figure_title", "raw_order": null, "bbox": [95, 1098, 1100, 1252], "text": "Figure 6. A,B) SEM image of scaffolds after soaking in SBF for 5 days (A1, A2: MBG/SF scaffold; B1, B2: MBG/PCL scaffold) and EDS spectra (A3: MBG/SF scaffold; B3:MBG/PCL scaffold). C) The relative expression of BMP-2, BSP, COL-1 and OCN of hBMSCs cultured on MBG/SF and MBG/PCL scaffolds for 7 and 14 days.[81] Copyright 2019, Elsevier. D) Schematic of fabrication of two-level macro and micro porous hierarchical CaP scaffolds a); The ceramic mandible and square shape specimens fabricated by 3D printing method. b–d). [32] Copyright 2018, Elsevier. E) The gross images of CLH (on the left, dyed with methyl orange), OLH (on the right) (a) and the bilayered hydrogels (b). F) 3D printability of the pregelation solution of the hydrogels. The designed patterns (a) and the 3D printed patterns by CLH pregel solution (b). G) Micro-CT analysis images, histological images of H&E, Masson, ARS and immunohistochemical staining for OCN after in vivo subcutaneous implantation for 28 days. Scale bar = 50 μm.[144] Copyright 2023, Wiley-VCH.", "page_width": 1191, "page_height": 1565, "role": "figure_caption", "role_confidence": 0.92, "evidence": ["figure_title label: Figure 6. A,B) SEM image of scaffolds after soaking in SBF f"], "seed_role": "figure_caption", "seed_confidence": 0.92, "seed_evidence": ["figure_title label: Figure 6. A,B) SEM image of scaffolds after soaking in SBF f"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaSansPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaSansPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaSansPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaSansPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaSansPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaSansPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "STIXMath-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "STIX-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaSansPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaSansPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaSansPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 25, "page": 15, "raw_label": "figure_title", "text": "Figure 6. A,B) SEM image of scaffolds after soaking in SBF for 5 days (A1, A2: MBG/SF scaffold; B1, B2: MBG/PCL scaffold) and EDS spectra (A3: MBG/SF scaffold; B3:MBG/PCL scaffold). C) The relative expression of BMP-2, BSP, COL-1 and OCN of hBMSCs cultured on MBG/SF and MBG/PCL scaffolds for 7 and 14 days.[81] Copyright 2019, Elsevier. D) Schematic of fabrication of two-level macro and micro porous hierarchical CaP scaffolds a); The ceramic mandible and square shape specimens fabricated by 3D printing method. b–d). [32] Copyright 2018, Elsevier. E) The gross images of CLH (on the left, dyed with methyl orange), OLH (on the right) (a) and the bilayered hydrogels (b). F) 3D printability of the pregelation solution of the hydrogels. The designed patterns (a) and the 3D printed patterns by CLH pregel solution (b). G) Micro-CT analysis images, histological images of H&E, Masson, ARS and immunohistochemical staining for OCN after in vivo subcutaneous implantation for 28 days. Scale bar = 50 μm.[144] Copyright 2023, Wiley-VCH.", "bbox": [95, 1098, 1100, 1252], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "figure_number", "raw_marker": "Figure 6", "number": 6, "kind": "figure", "normalized_text": "Figure 6. A,B) SEM image of scaffolds after soaking in SBF for 5 days (A1, A2: MBG/SF scaffold; B1, B2: MBG/PCL scaffold) and EDS spectra (A3: MBG/SF scaffold; B3:MBG/PCL scaffold). C) The relative expression of BMP-2, BSP, COL-1 and OCN of hBMSCs cultured on MBG/SF and MBG/PCL scaffolds for 7 and 14 days.[81] Copyright 2019, Elsevier. D) Schematic of fabrication of two-level macro and micro porous hierarchical CaP scaffolds a); The ceramic mandible and square shape specimens fabricated by 3D printing method. b–d). [32] Copyright 2018, Elsevier. E) The gross images of CLH (on the left, dyed with methyl orange), OLH (on the right) (a) and the bilayered hydrogels (b). F) 3D printability of the pregelation solution of the hydrogels. The designed patterns (a) and the 3D printed patterns by CLH pregel solution (b). G) Micro-CT analysis images, histological images of H&E, Masson, ARS and immunohistochemical staining for OCN after in vivo subcutaneous implantation for 28 days. Scale bar = 50 μm.[144] Copyright 2023, Wiley-VCH."}, "layout_signature": {"width": 1005, "width_bucket": 1000, "height": 154, "left": 95, "top": 1098, "right": 1100, "bottom": 1252, "x_center": 597.5, "x_center_bucket": 600, "y_center": 1175.0, "x_ratio": 0.5017, "y_ratio": 0.7508, "width_ratio": 0.8438, "height_ratio": 0.0984, "line_count": 1}, "span_signature": {"font_size": 7.86, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Bold", "bold": true, "italic": true, "span_count": 157}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "display_zone", "style_family": "legend_like", "style_family_authority": "figure_marker", "reading_band_id": "band_131", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.0, "decision": "body", "evidence": []}, "role_verification_status": "ACCEPT", "role_source": "accepted_figure_caption_artifact", "role_evidence": ["figure caption matched accepted figure artifact"]}
+{"paper_id": "2HEUD5P9", "page": 15, "block_id": 26, "raw_label": "text", "raw_order": 1, "bbox": [95, 1288, 587, 1399], "text": "mesoporous bioactive glass (MBG) to fabricate MBG/SF composite scaffolds by 3D printing, and the results revealed that the gene expression levels of common osteogenic biomarkers on MBG/SF scaffolds were significantly better than MBG/PCL scaffolds (Figure 6A–C). $ ^{[81]} $", "page_width": 1191, "page_height": 1565, "role": "body_paragraph", "role_confidence": 0.6, "evidence": ["default body_paragraph for text label"], "seed_role": "body_paragraph", "seed_confidence": 0.6, "seed_evidence": ["default body_paragraph for text label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Bold", "flags": 20, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Bold", "flags": 20, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 26, "page": 15, "raw_label": "text", "text": "mesoporous bioactive glass (MBG) to fabricate MBG/SF composite scaffolds by 3D printing, and the results revealed that the gene expression levels of common osteogenic biomarkers on MBG/SF scaffolds were significantly better than MBG/PCL scaffolds (Figure 6A–C). $ ^{[81]} $", "bbox": [95, 1288, 587, 1399], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "mesoporous bioactive glass (MBG) to fabricate MBG/SF composite scaffolds by 3D printing, and the results revealed that the gene expression levels of common osteogenic biomarkers on MBG/SF scaffolds were significantly better than MBG/PCL scaffolds (Figure 6A–C). $ ^{[81]} $"}, "layout_signature": {"width": 492, "width_bucket": 500, "height": 111, "left": 95, "top": 1288, "right": 587, "bottom": 1399, "x_center": 341.0, "x_center_bucket": 350, "y_center": 1343.5, "x_ratio": 0.2863, "y_ratio": 0.8585, "width_ratio": 0.4131, "height_ratio": 0.0709, "line_count": 1}, "span_signature": {"font_size": 8.76, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaPro-Regular", "bold": true, "italic": true, "span_count": 44}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_135", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "hard", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 15, "block_id": 27, "raw_label": "text", "raw_order": 2, "bbox": [96, 1399, 588, 1443], "text": "3D printing combined with 3D computer imaging and calculation software can be used to fabricate tailored implants with complex 3D structures for patients with bone tissue defects. $ ^{[135]} $ Precise control of the bulk geometry and internal structure of scaffolds is a major advantage of 3D printing technology in bone engineering. Several 3D printing technologies, including fused deposition modeling, stereolithography, and selective laser sintering, allow spatial control of the microarchitecture and composition of scaffolds at the micron scale, which more effectively mimics the", "page_width": 1191, "page_height": 1565, "role": "body_paragraph", "role_confidence": 0.6, "evidence": ["default body_paragraph for text label"], "seed_role": "body_paragraph", "seed_confidence": 0.6, "seed_evidence": ["default body_paragraph for text label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 27, "page": 15, "raw_label": "text", "text": "3D printing combined with 3D computer imaging and calculation software can be used to fabricate tailored implants with complex 3D structures for patients with bone tissue defects. $ ^{[135]} $ Precise control of the bulk geometry and internal structure of scaffolds is a major advantage of 3D printing technology in bone engineering. Several 3D printing technologies, including fused deposition modeling, stereolithography, and selective laser sintering, allow spatial control of the microarchitecture and composition of scaffolds at the micron scale, which more effectively mimics the", "bbox": [96, 1399, 588, 1443], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "3D printing combined with 3D computer imaging and calculation software can be used to fabricate tailored implants with complex 3D structures for patients with bone tissue defects. $ ^{[135]} $ Precise control of the bulk geometry and internal structure of scaffolds is a major advantage of 3D printing technology in bone engineering. Several 3D printing technologies, including fused deposition modeling, stereolithography, and selective laser sintering, allow spatial control of the microarchitecture and composition of scaffolds at the micron scale, which more effectively mimics the"}, "layout_signature": {"width": 492, "width_bucket": 500, "height": 44, "left": 96, "top": 1399, "right": 588, "bottom": 1443, "x_center": 342.0, "x_center_bucket": 350, "y_center": 1421.0, "x_ratio": 0.2872, "y_ratio": 0.908, "width_ratio": 0.4131, "height_ratio": 0.0281, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaPro-Regular", "bold": false, "italic": true, "span_count": 2}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_137", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 15, "block_id": 28, "raw_label": "text", "raw_order": 3, "bbox": [604, 1288, 1099, 1444], "text": "", "page_width": 1191, "page_height": 1565, "role": "ocr_text_missing", "role_confidence": 0.8, "evidence": ["ocr detected text region (raw_label=text) but no text extracted; no pdf backfill available"], "seed_role": "ocr_text_missing", "seed_confidence": 0.8, "seed_evidence": ["ocr detected text region (raw_label=text) but no text extracted; no pdf backfill available"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 28, "page": 15, "raw_label": "text", "text": "", "bbox": [604, 1288, 1099, 1444], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "empty", "raw_marker": null, "number": null, "kind": null, "normalized_text": ""}, "layout_signature": {"width": 495, "width_bucket": 500, "height": 156, "left": 604, "top": 1288, "right": 1099, "bottom": 1444, "x_center": 851.5, "x_center_bucket": 850, "y_center": 1366.0, "x_ratio": 0.7149, "y_ratio": 0.8728, "width_ratio": 0.4156, "height_ratio": 0.0997, "line_count": 1}, "span_signature": {"font_size": 8.22, "font_size_median": 8.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaPro-Regular", "bold": false, "italic": true, "span_count": 12}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": "pdf_text_layer_fallback_rejected", "_ocr_raw_status": "missing_text_rejected", "_ocr_raw_error_type": "backfill_overlaps_existing_text_block", "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "_needs_pdf_fallback": true, "reading_band_id": "band_137", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 15, "block_id": 29, "raw_label": "footer", "raw_order": null, "bbox": [99, 1487, 289, 1505], "text": "Small Methods 2024, 8, 2301283", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["footer label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["footer label"], "span_metadata": [{"size": 6.973800182342529, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 29, "page": 15, "raw_label": "footer", "text": "Small Methods 2024, 8, 2301283", "bbox": [99, 1487, 289, 1505], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "Small Methods 2024, 8, 2301283"}, "layout_signature": {"width": 190, "width_bucket": 200, "height": 18, "left": 99, "top": 1487, "right": 289, "bottom": 1505, "x_center": 194.0, "x_center_bucket": 200, "y_center": 1496.0, "x_ratio": 0.1629, "y_ratio": 0.9559, "width_ratio": 0.1595, "height_ratio": 0.0115, "line_count": 1}, "span_signature": {"font_size": 6.97, "font_size_median": 6.97, "font_size_bucket": 7.0, "font_family_norm": "ScalaSansPro-Italic", "bold": true, "italic": true, "span_count": 5}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_126", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 15, "block_id": 30, "raw_label": "number", "raw_order": null, "bbox": [526, 1483, 668, 1508], "text": "2301283 (15 of 27)", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["page number label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["page number label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaSansPro-Bold", "flags": 20, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 30, "page": 15, "raw_label": "number", "text": "2301283 (15 of 27)", "bbox": [526, 1483, 668, 1508], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_dot", "raw_marker": "2301283", "number": 2301283, "kind": "reference", "normalized_text": "2301283 (15 of 27)"}, "layout_signature": {"width": 142, "width_bucket": 150, "height": 25, "left": 526, "top": 1483, "right": 668, "bottom": 1508, "x_center": 597.0, "x_center_bucket": 600, "y_center": 1495.5, "x_ratio": 0.5013, "y_ratio": 0.9556, "width_ratio": 0.1192, "height_ratio": 0.016, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaSansPro-Bold", "bold": true, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "reference_like", "style_family_authority": "reference_family_anchor", "reading_band_id": "band_126", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 15, "block_id": 31, "raw_label": "footer", "raw_order": null, "bbox": [937, 1486, 1096, 1506], "text": "© 2024 Wiley-VCH GmbH", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["footer label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["footer label"], "span_metadata": [{"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 31, "page": 15, "raw_label": "footer", "text": "© 2024 Wiley-VCH GmbH", "bbox": [937, 1486, 1096, 1506], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "© 2024 Wiley-VCH GmbH"}, "layout_signature": {"width": 159, "width_bucket": 150, "height": 20, "left": 937, "top": 1486, "right": 1096, "bottom": 1506, "x_center": 1016.5, "x_center_bucket": 1025, "y_center": 1496.0, "x_ratio": 0.8535, "y_ratio": 0.9559, "width_ratio": 0.1335, "height_ratio": 0.0128, "line_count": 1}, "span_signature": {"font_size": 6.97, "font_size_median": 6.97, "font_size_bucket": 7.0, "font_family_norm": "ScalaSansPro-Regular", "bold": false, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_126", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 15, "block_id": 32, "raw_label": "aside_text", "raw_order": null, "bbox": [1154, 31, 1171, 1535], "text": "23699608, 2024, 8, Downloaded from https://onlinelibrary.wiley.com/doi/10.1002/smkt.202301283 by Shandong University Library, Wiley Online Library on [18/02/2026]. See the Terms and Conditions (https://onlinelibrary.wiley.com/terms-and-conditions) on Wiley Online Library for rules of use; OA articles are governed by the applicable Creative Commons License", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.95, "evidence": ["margin-band narrow/tall geometry; treated as noise"], "seed_role": "noise", "seed_confidence": 0.95, "seed_evidence": ["margin-band narrow/tall geometry; treated as noise"], "span_metadata": [{"size": 5.03000020980835, "font": "Times-Roman", "flags": 4, "color": 0, "dir": [0.0, 1.0], "wmode": 0}], "raw_observation": {"block_id": 32, "page": 15, "raw_label": "aside_text", "text": "23699608, 2024, 8, Downloaded from https://onlinelibrary.wiley.com/doi/10.1002/smkt.202301283 by Shandong University Library, Wiley Online Library on [18/02/2026]. See the Terms and Conditions (https://onlinelibrary.wiley.com/terms-and-conditions) on Wiley Online Library for rules of use; OA articles are governed by the applicable Creative Commons License", "bbox": [1154, 31, 1171, 1535], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "23699608, 2024, 8, Downloaded from https://onlinelibrary.wiley.com/doi/10.1002/smkt.202301283 by Shandong University Library, Wiley Online Library on [18/02/2026]. See the Terms and Conditions (https://onlinelibrary.wiley.com/terms-and-conditions) on Wiley Online Library for rules of use; OA articles are governed by the applicable Creative Commons License"}, "layout_signature": {"width": 17, "width_bucket": 25, "height": 1504, "left": 1154, "top": 31, "right": 1171, "bottom": 1535, "x_center": 1162.5, "x_center_bucket": 1150, "y_center": 783.0, "x_ratio": 0.9761, "y_ratio": 0.5003, "width_ratio": 0.0143, "height_ratio": 0.961, "line_count": 1}, "span_signature": {"font_size": 5.03, "font_size_median": 5.03, "font_size_bucket": 5.0, "font_family_norm": "Times-Roman", "bold": false, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_family_anchor", "reading_band_id": "band_126", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 16, "block_id": 0, "raw_label": "header", "raw_order": null, "bbox": [92, 46, 339, 116], "text": "ADVANCED\nSCIENCE NEWS\nwww.advancedsciencenews.com", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["header label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["header label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaSansPro-Bold", "flags": 20, "color": 255, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 0, "page": 16, "raw_label": "header", "text": "ADVANCED\nSCIENCE NEWS\nwww.advancedsciencenews.com", "bbox": [92, 46, 339, 116], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "ADVANCED\nSCIENCE NEWS\nwww.advancedsciencenews.com"}, "layout_signature": {"width": 247, "width_bucket": 250, "height": 70, "left": 92, "top": 46, "right": 339, "bottom": 116, "x_center": 215.5, "x_center_bucket": 225, "y_center": 81.0, "x_ratio": 0.1809, "y_ratio": 0.0518, "width_ratio": 0.2074, "height_ratio": 0.0447, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaSansPro-Bold", "bold": true, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 16, "block_id": 1, "raw_label": "header_image", "raw_order": null, "bbox": [997, 36, 1089, 97], "text": "", "page_width": 1191, "page_height": 1565, "role": "unknown_structural", "role_confidence": 0.2, "evidence": ["unrecognized label 'header_image'"], "seed_role": "unknown_structural", "seed_confidence": 0.2, "seed_evidence": ["unrecognized label 'header_image'"], "span_metadata": null, "raw_observation": {"block_id": 1, "page": 16, "raw_label": "header_image", "text": "", "bbox": [997, 36, 1089, 97], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "empty", "raw_marker": null, "number": null, "kind": null, "normalized_text": ""}, "layout_signature": {"width": 92, "width_bucket": 100, "height": 61, "left": 997, "top": 36, "right": 1089, "bottom": 97, "x_center": 1043.0, "x_center_bucket": 1050, "y_center": 66.5, "x_ratio": 0.8757, "y_ratio": 0.0425, "width_ratio": 0.0772, "height_ratio": 0.039, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": true, "zone": "body_zone", "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_142", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["non-structural role accepted"]}
+{"paper_id": "2HEUD5P9", "page": 16, "block_id": 2, "raw_label": "header", "raw_order": null, "bbox": [897, 98, 1090, 116], "text": "www.small-methods.com", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["header label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["header label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaSansPro-Bold", "flags": 20, "color": 255, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 2, "page": 16, "raw_label": "header", "text": "www.small-methods.com", "bbox": [897, 98, 1090, 116], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "www.small-methods.com"}, "layout_signature": {"width": 193, "width_bucket": 200, "height": 18, "left": 897, "top": 98, "right": 1090, "bottom": 116, "x_center": 993.5, "x_center_bucket": 1000, "y_center": 107.0, "x_ratio": 0.8342, "y_ratio": 0.0684, "width_ratio": 0.162, "height_ratio": 0.0115, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaSansPro-Bold", "bold": true, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_142", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 16, "block_id": 3, "raw_label": "text", "raw_order": 1, "bbox": [90, 149, 582, 436], "text": "architecture of native bone. $ ^{[136]} $ In addition, several 3D bioprinting techniques, such as inkjet, extrusion, and laser-assisted bioprinting, have been developed in regenerative medicine, which can deposit living cells, ECM, and other materials in user-defined patterns to build implants or complex tissues for bone-defect repair in orthopedics. 3D bioprinting can be used to manufacture artificial tissue scaffolds with controllable cell distributions. Cell spheroids exhibit improved ECM development and intercellular communication than cells cultured in a monolayer, potentially facilitating the growth of bioprinted structures towards specific tissues. The development of bioprinting protocols and compatible ink materials for bone tissue engineering has facilitated the manufacturing of superior tissue scaffolds for bone repair.", "page_width": 1191, "page_height": 1565, "role": "body_paragraph", "role_confidence": 0.6, "evidence": ["default body_paragraph for text label"], "seed_role": "body_paragraph", "seed_confidence": 0.6, "seed_evidence": ["default body_paragraph for text label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 3, "page": 16, "raw_label": "text", "text": "architecture of native bone. $ ^{[136]} $ In addition, several 3D bioprinting techniques, such as inkjet, extrusion, and laser-assisted bioprinting, have been developed in regenerative medicine, which can deposit living cells, ECM, and other materials in user-defined patterns to build implants or complex tissues for bone-defect repair in orthopedics. 3D bioprinting can be used to manufacture artificial tissue scaffolds with controllable cell distributions. Cell spheroids exhibit improved ECM development and intercellular communication than cells cultured in a monolayer, potentially facilitating the growth of bioprinted structures towards specific tissues. The development of bioprinting protocols and compatible ink materials for bone tissue engineering has facilitated the manufacturing of superior tissue scaffolds for bone repair.", "bbox": [90, 149, 582, 436], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "architecture of native bone. $ ^{[136]} $ In addition, several 3D bioprinting techniques, such as inkjet, extrusion, and laser-assisted bioprinting, have been developed in regenerative medicine, which can deposit living cells, ECM, and other materials in user-defined patterns to build implants or complex tissues for bone-defect repair in orthopedics. 3D bioprinting can be used to manufacture artificial tissue scaffolds with controllable cell distributions. Cell spheroids exhibit improved ECM development and intercellular communication than cells cultured in a monolayer, potentially facilitating the growth of bioprinted structures towards specific tissues. The development of bioprinting protocols and compatible ink materials for bone tissue engineering has facilitated the manufacturing of superior tissue scaffolds for bone repair."}, "layout_signature": {"width": 492, "width_bucket": 500, "height": 287, "left": 90, "top": 149, "right": 582, "bottom": 436, "x_center": 336.0, "x_center_bucket": 325, "y_center": 292.5, "x_ratio": 0.2821, "y_ratio": 0.1869, "width_ratio": 0.4131, "height_ratio": 0.1834, "line_count": 1}, "span_signature": {"font_size": 8.82, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaPro-Regular", "bold": false, "italic": true, "span_count": 60}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_139", "display_cluster_candidate_id": "disp_27_0", "layout_region": "display_zone", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 16, "block_id": 4, "raw_label": "paragraph_title", "raw_order": 2, "bbox": [91, 479, 439, 502], "text": "3.1.2. The Basic Requirements of Bone Scaffolds", "page_width": 1191, "page_height": 1565, "role": "sub_subsection_heading", "role_confidence": 0.85, "evidence": ["paragraph_title label with numbering: 3.1.2. The Basic Requirements of Bone Scaffolds"], "seed_role": "sub_subsection_heading", "seed_confidence": 0.85, "seed_evidence": ["paragraph_title label with numbering: 3.1.2. The Basic Requirements of Bone Scaffolds"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaSansPro-Italic", "flags": 6, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 4, "page": 16, "raw_label": "paragraph_title", "text": "3.1.2. The Basic Requirements of Bone Scaffolds", "bbox": [91, 479, 439, 502], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "heading_numbered", "raw_marker": "3.1.2", "number": "3.1.2", "kind": "heading", "normalized_text": "3.1.2. The Basic Requirements of Bone Scaffolds"}, "layout_signature": {"width": 348, "width_bucket": 350, "height": 23, "left": 91, "top": 479, "right": 439, "bottom": 502, "x_center": 265.0, "x_center_bucket": 275, "y_center": 490.5, "x_ratio": 0.2225, "y_ratio": 0.3134, "width_ratio": 0.2922, "height_ratio": 0.0147, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaSansPro-Italic", "bold": false, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_140", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 16, "block_id": 5, "raw_label": "text", "raw_order": 3, "bbox": [90, 521, 582, 1115], "text": "The mechanical integrity, microstructure, biocompatibility, biodegradability, and osteoconductivity are crucial properties of scaffolds for bone repair and regeneration, and it is essential to achieve an equilibrium of cell viability, cell function, and mechanical properties under weight-bearing conditions. Bone scaffolds must exhibit superior mechanical strength and promote bone cell adhesion, migration, proliferation, and osteogenic differentiation, without triggering immune or inflammatory responses. Strict control over the mechanical properties, topography, and porosity of scaffolds is essential for bone repair and regeneration. The mechanical properties of scaffolds, determined by the material properties and pore structures, should provide sufficient mechanical strength for structures in load-bearing bones until new bone formation. Porous structures are conducive to the diffusion of metabolic wastes and nutrients and enhance the metabolism of osteoblasts. $ ^{[137]} $ An interconnected porous structure with a porosity of more than 90% and pore size between 300 and 500 $ \\mu $m facilitates nutrient delivery, cell penetration, and vascularization. $ ^{[137]} $ Bioprinted scaffolds should gradually degrade with cell growth, and the degradation rate of the scaffolds should match the rate of new bone formation. Meanwhile, the degradation products should have no toxic effects and should be excreted from the human body through metabolism. The osteoconductivity of scaffolds is conducive to ECM formation on their surface and pores and can suppress the generation of fibrous tissue encapsulation, forming a connection between the bone and scaffold.", "page_width": 1191, "page_height": 1565, "role": "body_paragraph", "role_confidence": 0.6, "evidence": ["default body_paragraph for text label"], "seed_role": "body_paragraph", "seed_confidence": 0.6, "seed_evidence": ["default body_paragraph for text label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "STIX-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "STIX-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 5, "page": 16, "raw_label": "text", "text": "The mechanical integrity, microstructure, biocompatibility, biodegradability, and osteoconductivity are crucial properties of scaffolds for bone repair and regeneration, and it is essential to achieve an equilibrium of cell viability, cell function, and mechanical properties under weight-bearing conditions. Bone scaffolds must exhibit superior mechanical strength and promote bone cell adhesion, migration, proliferation, and osteogenic differentiation, without triggering immune or inflammatory responses. Strict control over the mechanical properties, topography, and porosity of scaffolds is essential for bone repair and regeneration. The mechanical properties of scaffolds, determined by the material properties and pore structures, should provide sufficient mechanical strength for structures in load-bearing bones until new bone formation. Porous structures are conducive to the diffusion of metabolic wastes and nutrients and enhance the metabolism of osteoblasts. $ ^{[137]} $ An interconnected porous structure with a porosity of more than 90% and pore size between 300 and 500 $ \\mu $m facilitates nutrient delivery, cell penetration, and vascularization. $ ^{[137]} $ Bioprinted scaffolds should gradually degrade with cell growth, and the degradation rate of the scaffolds should match the rate of new bone formation. Meanwhile, the degradation products should have no toxic effects and should be excreted from the human body through metabolism. The osteoconductivity of scaffolds is conducive to ECM formation on their surface and pores and can suppress the generation of fibrous tissue encapsulation, forming a connection between the bone and scaffold.", "bbox": [90, 521, 582, 1115], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "The mechanical integrity, microstructure, biocompatibility, biodegradability, and osteoconductivity are crucial properties of scaffolds for bone repair and regeneration, and it is essential to achieve an equilibrium of cell viability, cell function, and mechanical properties under weight-bearing conditions. Bone scaffolds must exhibit superior mechanical strength and promote bone cell adhesion, migration, proliferation, and osteogenic differentiation, without triggering immune or inflammatory responses. Strict control over the mechanical properties, topography, and porosity of scaffolds is essential for bone repair and regeneration. The mechanical properties of scaffolds, determined by the material properties and pore structures, should provide sufficient mechanical strength for structures in load-bearing bones until new bone formation. Porous structures are conducive to the diffusion of metabolic wastes and nutrients and enhance the metabolism of osteoblasts. $ ^{[137]} $ An interconnected porous structure with a porosity of more than 90% and pore size between 300 and 500 $ \\mu $m facilitates nutrient delivery, cell penetration, and vascularization. $ ^{[137]} $ Bioprinted scaffolds should gradually degrade with cell growth, and the degradation rate of the scaffolds should match the rate of new bone formation. Meanwhile, the degradation products should have no toxic effects and should be excreted from the human body through metabolism. The osteoconductivity of scaffolds is conducive to ECM formation on their surface and pores and can suppress the generation of fibrous tissue encapsulation, forming a connection between the bone and scaffold."}, "layout_signature": {"width": 492, "width_bucket": 500, "height": 594, "left": 90, "top": 521, "right": 582, "bottom": 1115, "x_center": 336.0, "x_center_bucket": 325, "y_center": 818.0, "x_ratio": 0.2821, "y_ratio": 0.5227, "width_ratio": 0.4131, "height_ratio": 0.3796, "line_count": 1}, "span_signature": {"font_size": 8.91, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaPro-Regular", "bold": false, "italic": true, "span_count": 348}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_139", "display_cluster_candidate_id": "disp_27_0", "layout_region": "display_zone", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 16, "block_id": 6, "raw_label": "text", "raw_order": 4, "bbox": [89, 1114, 583, 1445], "text": "Postprint modification is often applied to improve the performance of bone scaffolds and obtain the desired effect. Such modifications can promote stem cell proliferation and differentiation, and improve post-transplant histocompatibility. For example, a 3D-printed PCL scaffold modified with acetone and ultrasonic treatment led to increased surface roughness, greater surface area, reduced hydrophobicity, and promoted the osteogenic differentiation of MSCs compared with pure PCL scaffolds.[138] In addition, bone scaffolds should be mass-produced and should have desirable properties that facilitate 3D printing into tailored constructs for bone defects. In 3D printing process, the printing ink formulation will influence on the ceramic macro and micro porous architectures. HA powders of nano-sized grains (NP) with diameters of 30–50 nm, air jet milling powders (AP) with diameters of 10–30 μm, and spherical powder (SP) with diameters of 10–50 μm, were used as the initial printing materials in the printing ink formulations (Figure 6D).[32]", "page_width": 1191, "page_height": 1565, "role": "body_paragraph", "role_confidence": 0.6, "evidence": ["default body_paragraph for text label"], "seed_role": "body_paragraph", "seed_confidence": 0.6, "seed_evidence": ["default body_paragraph for text label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "STIX-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 6, "page": 16, "raw_label": "text", "text": "Postprint modification is often applied to improve the performance of bone scaffolds and obtain the desired effect. Such modifications can promote stem cell proliferation and differentiation, and improve post-transplant histocompatibility. For example, a 3D-printed PCL scaffold modified with acetone and ultrasonic treatment led to increased surface roughness, greater surface area, reduced hydrophobicity, and promoted the osteogenic differentiation of MSCs compared with pure PCL scaffolds.[138] In addition, bone scaffolds should be mass-produced and should have desirable properties that facilitate 3D printing into tailored constructs for bone defects. In 3D printing process, the printing ink formulation will influence on the ceramic macro and micro porous architectures. HA powders of nano-sized grains (NP) with diameters of 30–50 nm, air jet milling powders (AP) with diameters of 10–30 μm, and spherical powder (SP) with diameters of 10–50 μm, were used as the initial printing materials in the printing ink formulations (Figure 6D).[32]", "bbox": [89, 1114, 583, 1445], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "Postprint modification is often applied to improve the performance of bone scaffolds and obtain the desired effect. Such modifications can promote stem cell proliferation and differentiation, and improve post-transplant histocompatibility. For example, a 3D-printed PCL scaffold modified with acetone and ultrasonic treatment led to increased surface roughness, greater surface area, reduced hydrophobicity, and promoted the osteogenic differentiation of MSCs compared with pure PCL scaffolds.[138] In addition, bone scaffolds should be mass-produced and should have desirable properties that facilitate 3D printing into tailored constructs for bone defects. In 3D printing process, the printing ink formulation will influence on the ceramic macro and micro porous architectures. HA powders of nano-sized grains (NP) with diameters of 30–50 nm, air jet milling powders (AP) with diameters of 10–30 μm, and spherical powder (SP) with diameters of 10–50 μm, were used as the initial printing materials in the printing ink formulations (Figure 6D).[32]"}, "layout_signature": {"width": 494, "width_bucket": 500, "height": 331, "left": 89, "top": 1114, "right": 583, "bottom": 1445, "x_center": 336.0, "x_center_bucket": 325, "y_center": 1279.5, "x_ratio": 0.2821, "y_ratio": 0.8176, "width_ratio": 0.4148, "height_ratio": 0.2115, "line_count": 1}, "span_signature": {"font_size": 8.83, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaPro-Regular", "bold": false, "italic": true, "span_count": 68}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_140", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 16, "block_id": 7, "raw_label": "text", "raw_order": 5, "bbox": [601, 148, 1091, 195], "text": "", "page_width": 1191, "page_height": 1565, "role": "ocr_text_missing", "role_confidence": 0.8, "evidence": ["ocr detected text region (raw_label=text) but no text extracted; no pdf backfill available"], "seed_role": "ocr_text_missing", "seed_confidence": 0.8, "seed_evidence": ["ocr detected text region (raw_label=text) but no text extracted; no pdf backfill available"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "STIX-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 7, "page": 16, "raw_label": "text", "text": "", "bbox": [601, 148, 1091, 195], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "empty", "raw_marker": null, "number": null, "kind": null, "normalized_text": ""}, "layout_signature": {"width": 490, "width_bucket": 500, "height": 47, "left": 601, "top": 148, "right": 1091, "bottom": 195, "x_center": 846.0, "x_center_bucket": 850, "y_center": 171.5, "x_ratio": 0.7103, "y_ratio": 0.1096, "width_ratio": 0.4114, "height_ratio": 0.03, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 8.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaPro-Regular", "bold": false, "italic": true, "span_count": 9}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": "pdf_text_layer_fallback_rejected", "_ocr_raw_status": "missing_text_rejected", "_ocr_raw_error_type": "backfill_overlaps_existing_text_block", "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "_needs_pdf_fallback": true, "reading_band_id": "band_139", "display_cluster_candidate_id": "disp_27_0", "layout_region": "display_zone", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 16, "block_id": 8, "raw_label": "paragraph_title", "raw_order": 6, "bbox": [602, 238, 913, 260], "text": "3.1.3. 3D-Printed Scaffolds for Bone Repair", "page_width": 1191, "page_height": 1565, "role": "sub_subsection_heading", "role_confidence": 0.85, "evidence": ["paragraph_title label with numbering: 3.1.3. 3D-Printed Scaffolds for Bone Repair"], "seed_role": "sub_subsection_heading", "seed_confidence": 0.85, "seed_evidence": ["paragraph_title label with numbering: 3.1.3. 3D-Printed Scaffolds for Bone Repair"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaSansPro-Italic", "flags": 6, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 8, "page": 16, "raw_label": "paragraph_title", "text": "3.1.3. 3D-Printed Scaffolds for Bone Repair", "bbox": [602, 238, 913, 260], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "3.1.3. 3D-Printed Scaffolds for Bone Repair"}, "layout_signature": {"width": 311, "width_bucket": 300, "height": 22, "left": 602, "top": 238, "right": 913, "bottom": 260, "x_center": 757.5, "x_center_bucket": 750, "y_center": 249.0, "x_ratio": 0.636, "y_ratio": 0.1591, "width_ratio": 0.2611, "height_ratio": 0.0141, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaSansPro-Italic", "bold": false, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_140", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 16, "block_id": 9, "raw_label": "text", "raw_order": 7, "bbox": [598, 281, 1093, 1158], "text": "Composites can combine the merits of two or more different types of materials and thus meet the performance requirements of bone scaffolds to a large extent, including mechanical and biological properties, ease of manufacturing, and controllable degradation. Therefore, 3D-printed biodegradable composites have been extensively developed for bone tissue engineering applications. A cell-laden $ \\alpha $-TCP/collagen scaffold fabricated using a two-step printing process showed improved metabolic activity and mineralization of preosteoblasts and had potential application in bone repair and regeneration. $ ^{[139]} $ Gelatin/ $ \\alpha $-TCP/silk-fibroin designed by a temperature-controlled 3D printing process could enhance mechanical strength and significantly promote cell proliferation and differentiation of MG63 cells compared to a gelatin or gelatin/ $ \\alpha $-TCP scaffold. $ ^{[140]} $ Cell-laden ECM-ornamented 3D-printed PCL/PLGA/TCP composite scaffold accelerated osteoblastic differentiation and calcium deposition in vitro, and induced new bone formation in vivo, allowing this composite to be used as an off-the-shelf bone graft scaffold. $ ^{[141]} $ Bionic porous 3D collagen/HAP scaffolds retain the natural properties of the material after printing and increased cell proliferation, penetration, and mineralization and accelerated new bone formation in a rabbit femoral condyle defect model. $ ^{[142]} $ The 3D-printed HAP/PCL scaffold exhibited good elasticity and toughness, supported cell proliferation and viability, and promoted osteogenic differentiation without osteoinducing factors. The porous scaffold could integrate with the surrounding bone tissues and facilitate bone-defect repair without eliciting an immune response. $ ^{[143]} $ However, 3D printing technology has several drawbacks. The bioink of 3D bioprinting mainly comprises living cells and bioactive polymers, whereas few cells are extracted from patients, and foreign cells may trigger an immune response and pathogen infection. The polymers used in bioinks are limited owing to strict requirements for cytocompatibility and biodegradation. In addition, 3D bioprinting technology only builds tissues with a single function, whereas tissues with complex structures and physiological functions are difficult to print. The biomimetic construct of kartogenin (KGN) in the two well-integrated zones of chondral layer hydrogel (CLH) and osseous layer hydrogel (OLH) is developed, which can facilitate cartilage and subchondral bone restoration in the in vivo osteochondral defect (Figure 6E–G). $ ^{[144]} $", "page_width": 1191, "page_height": 1565, "role": "body_paragraph", "role_confidence": 0.6, "evidence": ["default body_paragraph for text label"], "seed_role": "body_paragraph", "seed_confidence": 0.6, "seed_evidence": ["default body_paragraph for text label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "STIXMath-Italic", "flags": 6, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "STIXMath-Italic", "flags": 6, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "STIXMath-Italic", "flags": 6, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "STIXMath-Italic", "flags": 6, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 9, "page": 16, "raw_label": "text", "text": "Composites can combine the merits of two or more different types of materials and thus meet the performance requirements of bone scaffolds to a large extent, including mechanical and biological properties, ease of manufacturing, and controllable degradation. Therefore, 3D-printed biodegradable composites have been extensively developed for bone tissue engineering applications. A cell-laden $ \\alpha $-TCP/collagen scaffold fabricated using a two-step printing process showed improved metabolic activity and mineralization of preosteoblasts and had potential application in bone repair and regeneration. $ ^{[139]} $ Gelatin/ $ \\alpha $-TCP/silk-fibroin designed by a temperature-controlled 3D printing process could enhance mechanical strength and significantly promote cell proliferation and differentiation of MG63 cells compared to a gelatin or gelatin/ $ \\alpha $-TCP scaffold. $ ^{[140]} $ Cell-laden ECM-ornamented 3D-printed PCL/PLGA/TCP composite scaffold accelerated osteoblastic differentiation and calcium deposition in vitro, and induced new bone formation in vivo, allowing this composite to be used as an off-the-shelf bone graft scaffold. $ ^{[141]} $ Bionic porous 3D collagen/HAP scaffolds retain the natural properties of the material after printing and increased cell proliferation, penetration, and mineralization and accelerated new bone formation in a rabbit femoral condyle defect model. $ ^{[142]} $ The 3D-printed HAP/PCL scaffold exhibited good elasticity and toughness, supported cell proliferation and viability, and promoted osteogenic differentiation without osteoinducing factors. The porous scaffold could integrate with the surrounding bone tissues and facilitate bone-defect repair without eliciting an immune response. $ ^{[143]} $ However, 3D printing technology has several drawbacks. The bioink of 3D bioprinting mainly comprises living cells and bioactive polymers, whereas few cells are extracted from patients, and foreign cells may trigger an immune response and pathogen infection. The polymers used in bioinks are limited owing to strict requirements for cytocompatibility and biodegradation. In addition, 3D bioprinting technology only builds tissues with a single function, whereas tissues with complex structures and physiological functions are difficult to print. The biomimetic construct of kartogenin (KGN) in the two well-integrated zones of chondral layer hydrogel (CLH) and osseous layer hydrogel (OLH) is developed, which can facilitate cartilage and subchondral bone restoration in the in vivo osteochondral defect (Figure 6E–G). $ ^{[144]} $", "bbox": [598, 281, 1093, 1158], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "Composites can combine the merits of two or more different types of materials and thus meet the performance requirements of bone scaffolds to a large extent, including mechanical and biological properties, ease of manufacturing, and controllable degradation. Therefore, 3D-printed biodegradable composites have been extensively developed for bone tissue engineering applications. A cell-laden $ \\alpha $-TCP/collagen scaffold fabricated using a two-step printing process showed improved metabolic activity and mineralization of preosteoblasts and had potential application in bone repair and regeneration. $ ^{[139]} $ Gelatin/ $ \\alpha $-TCP/silk-fibroin designed by a temperature-controlled 3D printing process could enhance mechanical strength and significantly promote cell proliferation and differentiation of MG63 cells compared to a gelatin or gelatin/ $ \\alpha $-TCP scaffold. $ ^{[140]} $ Cell-laden ECM-ornamented 3D-printed PCL/PLGA/TCP composite scaffold accelerated osteoblastic differentiation and calcium deposition in vitro, and induced new bone formation in vivo, allowing this composite to be used as an off-the-shelf bone graft scaffold. $ ^{[141]} $ Bionic porous 3D collagen/HAP scaffolds retain the natural properties of the material after printing and increased cell proliferation, penetration, and mineralization and accelerated new bone formation in a rabbit femoral condyle defect model. $ ^{[142]} $ The 3D-printed HAP/PCL scaffold exhibited good elasticity and toughness, supported cell proliferation and viability, and promoted osteogenic differentiation without osteoinducing factors. The porous scaffold could integrate with the surrounding bone tissues and facilitate bone-defect repair without eliciting an immune response. $ ^{[143]} $ However, 3D printing technology has several drawbacks. The bioink of 3D bioprinting mainly comprises living cells and bioactive polymers, whereas few cells are extracted from patients, and foreign cells may trigger an immune response and pathogen infection. The polymers used in bioinks are limited owing to strict requirements for cytocompatibility and biodegradation. In addition, 3D bioprinting technology only builds tissues with a single function, whereas tissues with complex structures and physiological functions are difficult to print. The biomimetic construct of kartogenin (KGN) in the two well-integrated zones of chondral layer hydrogel (CLH) and osseous layer hydrogel (OLH) is developed, which can facilitate cartilage and subchondral bone restoration in the in vivo osteochondral defect (Figure 6E–G). $ ^{[144]} $"}, "layout_signature": {"width": 495, "width_bucket": 500, "height": 877, "left": 598, "top": 281, "right": 1093, "bottom": 1158, "x_center": 845.5, "x_center_bucket": 850, "y_center": 719.5, "x_ratio": 0.7099, "y_ratio": 0.4597, "width_ratio": 0.4156, "height_ratio": 0.5604, "line_count": 1}, "span_signature": {"font_size": 8.81, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaPro-Regular", "bold": false, "italic": true, "span_count": 339}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_138", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 16, "block_id": 10, "raw_label": "text", "raw_order": 8, "bbox": [598, 1158, 1093, 1445], "text": "In recent years, increasing researchers have applied 3D printing technology to bone tissue regeneration. Polymer materials and hydrogel materials have their own advantages and disadvantages in bone repair applications. Single materials often cannot balance mechanical strength, printability, biocompatibility/bioactivity, and bone conduction. Through 3D printing technology, more precise bone tissue composite scaffolds can be manufactured. These scaffolds can better adapt to the shape of the patient's bone defect and allow new tissue infiltration, thereby showing better bone repair efficacy. In the future, 3D printing technology will continue to develop biomimetic ultrafine models, in-depth research on the microstructure characteristics of tantalum metal and its impact on biological function,", "page_width": 1191, "page_height": 1565, "role": "body_paragraph", "role_confidence": 0.6, "evidence": ["default body_paragraph for text label"], "seed_role": "body_paragraph", "seed_confidence": 0.6, "seed_evidence": ["default body_paragraph for text label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 10, "page": 16, "raw_label": "text", "text": "In recent years, increasing researchers have applied 3D printing technology to bone tissue regeneration. Polymer materials and hydrogel materials have their own advantages and disadvantages in bone repair applications. Single materials often cannot balance mechanical strength, printability, biocompatibility/bioactivity, and bone conduction. Through 3D printing technology, more precise bone tissue composite scaffolds can be manufactured. These scaffolds can better adapt to the shape of the patient's bone defect and allow new tissue infiltration, thereby showing better bone repair efficacy. In the future, 3D printing technology will continue to develop biomimetic ultrafine models, in-depth research on the microstructure characteristics of tantalum metal and its impact on biological function,", "bbox": [598, 1158, 1093, 1445], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "In recent years, increasing researchers have applied 3D printing technology to bone tissue regeneration. Polymer materials and hydrogel materials have their own advantages and disadvantages in bone repair applications. Single materials often cannot balance mechanical strength, printability, biocompatibility/bioactivity, and bone conduction. Through 3D printing technology, more precise bone tissue composite scaffolds can be manufactured. These scaffolds can better adapt to the shape of the patient's bone defect and allow new tissue infiltration, thereby showing better bone repair efficacy. In the future, 3D printing technology will continue to develop biomimetic ultrafine models, in-depth research on the microstructure characteristics of tantalum metal and its impact on biological function,"}, "layout_signature": {"width": 495, "width_bucket": 500, "height": 287, "left": 598, "top": 1158, "right": 1093, "bottom": 1445, "x_center": 845.5, "x_center_bucket": 850, "y_center": 1301.5, "x_ratio": 0.7099, "y_ratio": 0.8316, "width_ratio": 0.4156, "height_ratio": 0.1834, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaPro-Regular", "bold": false, "italic": true, "span_count": 159}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_141", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "hard", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 16, "block_id": 11, "raw_label": "footer", "raw_order": null, "bbox": [94, 1487, 283, 1505], "text": "Small Methods 2024, 8, 2301283", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["footer label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["footer label"], "span_metadata": [{"size": 6.973800182342529, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 11, "page": 16, "raw_label": "footer", "text": "Small Methods 2024, 8, 2301283", "bbox": [94, 1487, 283, 1505], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "Small Methods 2024, 8, 2301283"}, "layout_signature": {"width": 189, "width_bucket": 200, "height": 18, "left": 94, "top": 1487, "right": 283, "bottom": 1505, "x_center": 188.5, "x_center_bucket": 200, "y_center": 1496.0, "x_ratio": 0.1583, "y_ratio": 0.9559, "width_ratio": 0.1587, "height_ratio": 0.0115, "line_count": 1}, "span_signature": {"font_size": 6.97, "font_size_median": 6.97, "font_size_bucket": 7.0, "font_family_norm": "ScalaSansPro-Italic", "bold": true, "italic": true, "span_count": 5}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_142", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 16, "block_id": 12, "raw_label": "footer", "raw_order": null, "bbox": [520, 1484, 663, 1507], "text": "2301283 (16 of 27)", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["footer label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["footer label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaSansPro-Bold", "flags": 20, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 12, "page": 16, "raw_label": "footer", "text": "2301283 (16 of 27)", "bbox": [520, 1484, 663, 1507], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_dot", "raw_marker": "2301283", "number": 2301283, "kind": "reference", "normalized_text": "2301283 (16 of 27)"}, "layout_signature": {"width": 143, "width_bucket": 150, "height": 23, "left": 520, "top": 1484, "right": 663, "bottom": 1507, "x_center": 591.5, "x_center_bucket": 600, "y_center": 1495.5, "x_ratio": 0.4966, "y_ratio": 0.9556, "width_ratio": 0.1201, "height_ratio": 0.0147, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaSansPro-Bold", "bold": true, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "reference_like", "style_family_authority": "reference_family_anchor", "reading_band_id": "band_142", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 16, "block_id": 13, "raw_label": "footer", "raw_order": null, "bbox": [931, 1487, 1090, 1506], "text": "© 2024 Wiley-VCH GmbH", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["footer label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["footer label"], "span_metadata": [{"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 13, "page": 16, "raw_label": "footer", "text": "© 2024 Wiley-VCH GmbH", "bbox": [931, 1487, 1090, 1506], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "© 2024 Wiley-VCH GmbH"}, "layout_signature": {"width": 159, "width_bucket": 150, "height": 19, "left": 931, "top": 1487, "right": 1090, "bottom": 1506, "x_center": 1010.5, "x_center_bucket": 1000, "y_center": 1496.5, "x_ratio": 0.8484, "y_ratio": 0.9562, "width_ratio": 0.1335, "height_ratio": 0.0121, "line_count": 1}, "span_signature": {"font_size": 6.97, "font_size_median": 6.97, "font_size_bucket": 7.0, "font_family_norm": "ScalaSansPro-Regular", "bold": false, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_136", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 16, "block_id": 14, "raw_label": "aside_text", "raw_order": null, "bbox": [1153, 29, 1171, 1533], "text": "23669608, 2024, 8, Downloaded from https://onlinelibrary.wiley.com/doi/10.1002/snmd.202301283 by Shandong University Library, Wiley Online Library on [18/02/2026]. See the Terms and Conditions (https://onlinelibrary.wiley.com/terms-and-conditions) on Wiley Online Library for rules of use; OA articles are governed by the applicable Creative Commons Licenses.", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.95, "evidence": ["margin-band narrow/tall geometry; treated as noise"], "seed_role": "noise", "seed_confidence": 0.95, "seed_evidence": ["margin-band narrow/tall geometry; treated as noise"], "span_metadata": [{"size": 5.03000020980835, "font": "Times-Roman", "flags": 4, "color": 0, "dir": [0.0, 1.0], "wmode": 0}], "raw_observation": {"block_id": 14, "page": 16, "raw_label": "aside_text", "text": "23669608, 2024, 8, Downloaded from https://onlinelibrary.wiley.com/doi/10.1002/snmd.202301283 by Shandong University Library, Wiley Online Library on [18/02/2026]. See the Terms and Conditions (https://onlinelibrary.wiley.com/terms-and-conditions) on Wiley Online Library for rules of use; OA articles are governed by the applicable Creative Commons Licenses.", "bbox": [1153, 29, 1171, 1533], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "23669608, 2024, 8, Downloaded from https://onlinelibrary.wiley.com/doi/10.1002/snmd.202301283 by Shandong University Library, Wiley Online Library on [18/02/2026]. See the Terms and Conditions (https://onlinelibrary.wiley.com/terms-and-conditions) on Wiley Online Library for rules of use; OA articles are governed by the applicable Creative Commons Licenses."}, "layout_signature": {"width": 18, "width_bucket": 25, "height": 1504, "left": 1153, "top": 29, "right": 1171, "bottom": 1533, "x_center": 1162.0, "x_center_bucket": 1150, "y_center": 781.0, "x_ratio": 0.9757, "y_ratio": 0.499, "width_ratio": 0.0151, "height_ratio": 0.961, "line_count": 1}, "span_signature": {"font_size": 5.03, "font_size_median": 5.03, "font_size_bucket": 5.0, "font_family_norm": "Times-Roman", "bold": false, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_family_anchor", "reading_band_id": "band_136", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 17, "block_id": 0, "raw_label": "header", "raw_order": null, "bbox": [98, 44, 345, 116], "text": "ADVANCED\nSCIENCE NEWS\nwww.advancedsciencenews.com", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["header label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["header label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaSansPro-Bold", "flags": 20, "color": 255, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 0, "page": 17, "raw_label": "header", "text": "ADVANCED\nSCIENCE NEWS\nwww.advancedsciencenews.com", "bbox": [98, 44, 345, 116], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "ADVANCED\nSCIENCE NEWS\nwww.advancedsciencenews.com"}, "layout_signature": {"width": 247, "width_bucket": 250, "height": 72, "left": 98, "top": 44, "right": 345, "bottom": 116, "x_center": 221.5, "x_center_bucket": 225, "y_center": 80.0, "x_ratio": 0.186, "y_ratio": 0.0511, "width_ratio": 0.2074, "height_ratio": 0.046, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaSansPro-Bold", "bold": true, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 17, "block_id": 1, "raw_label": "header", "raw_order": null, "bbox": [901, 36, 1097, 117], "text": "small methods\nwww.small-methods.com", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["header label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["header label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaSansPro-Bold", "flags": 20, "color": 255, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 1, "page": 17, "raw_label": "header", "text": "small methods\nwww.small-methods.com", "bbox": [901, 36, 1097, 117], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "small methods\nwww.small-methods.com"}, "layout_signature": {"width": 196, "width_bucket": 200, "height": 81, "left": 901, "top": 36, "right": 1097, "bottom": 117, "x_center": 999.0, "x_center_bucket": 1000, "y_center": 76.5, "x_ratio": 0.8388, "y_ratio": 0.0489, "width_ratio": 0.1646, "height_ratio": 0.0518, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaSansPro-Bold", "bold": true, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_142", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 17, "block_id": 2, "raw_label": "figure_title", "raw_order": null, "bbox": [97, 149, 743, 171], "text": "Table 3. Summarization of physical stimuli-responsive strategies: advantages and disadvantages.", "page_width": 1191, "page_height": 1565, "role": "table_caption", "role_confidence": 0.9, "evidence": ["table prefix matched: Table 3. Summarization of physical stimuli-responsive strate"], "seed_role": "table_caption", "seed_confidence": 0.9, "seed_evidence": ["table prefix matched: Table 3. Summarization of physical stimuli-responsive strate"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 2, "page": 17, "raw_label": "figure_title", "text": "Table 3. Summarization of physical stimuli-responsive strategies: advantages and disadvantages.", "bbox": [97, 149, 743, 171], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "table_number", "raw_marker": "Table 3", "number": 3, "kind": "table", "normalized_text": "Table 3. Summarization of physical stimuli-responsive strategies: advantages and disadvantages."}, "layout_signature": {"width": 646, "width_bucket": 650, "height": 22, "left": 97, "top": 149, "right": 743, "bottom": 171, "x_center": 420.0, "x_center_bucket": 425, "y_center": 160.0, "x_ratio": 0.3526, "y_ratio": 0.1022, "width_ratio": 0.5424, "height_ratio": 0.0141, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Bold", "bold": true, "italic": true, "span_count": 2}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "display_zone", "style_family": "table_caption_like", "style_family_authority": "table_marker", "reading_band_id": "band_142", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.0, "decision": "body", "evidence": []}, "role_verification_status": "ACCEPT", "role_source": "text_evidence_table_caption", "role_evidence": ["table caption accepted via text-prefix + marker/zone evidence"]}
+{"paper_id": "2HEUD5P9", "page": 17, "block_id": 3, "raw_label": "table", "raw_order": null, "bbox": [97, 183, 1092, 577], "text": "| Type of physical stimuli-responsive strategies | Advantages | Disadvantages | References. |
| Photoresponsive strategy | Noninvasive with high controllability Precise multistaged light program Superior photothermal therapy effects | Low tissue penetration Phototoxicity | [146,147] |
| Electroresponsive strategy | Effective tissue regeneration Improved conductive properties Suitable mechanical properties | Low control precision Undesirable biocompatibility and biodegradability Restricted electrical stimulation | [150,151] |
| Magnetic-responsive strategy | High tissue-penetrating capabilities High control precision | Uncertain biocompatibility and Long-term safety | [154,155] |
| Ultrasound-responsive strategy | Superior tissue penetration depth No drug resistance Non-invasive Cytocompatible; Biocompatible | Low in vivo stability of sonosensitizer drugs Potential toxicity of sonosensitizers | [159,160] |
| Piezoelectricity-responsive strategy | Improved conductive characteristics Excellrnt regeneration effect Biocompatibility and non-toxicity | Unfavorable biodegradability Long-term biosafet | [161,162] |
", "page_width": 1191, "page_height": 1565, "role": "table_html", "role_confidence": 0.85, "evidence": ["media label: table"], "seed_role": "media_asset", "seed_confidence": 0.85, "seed_evidence": ["media label: table"], "span_metadata": [{"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 3, "page": 17, "raw_label": "table", "text": "| Type of physical stimuli-responsive strategies | Advantages | Disadvantages | References. |
| Photoresponsive strategy | Noninvasive with high controllability Precise multistaged light program Superior photothermal therapy effects | Low tissue penetration Phototoxicity | [146,147] |
| Electroresponsive strategy | Effective tissue regeneration Improved conductive properties Suitable mechanical properties | Low control precision Undesirable biocompatibility and biodegradability Restricted electrical stimulation | [150,151] |
| Magnetic-responsive strategy | High tissue-penetrating capabilities High control precision | Uncertain biocompatibility and Long-term safety | [154,155] |
| Ultrasound-responsive strategy | Superior tissue penetration depth No drug resistance Non-invasive Cytocompatible; Biocompatible | Low in vivo stability of sonosensitizer drugs Potential toxicity of sonosensitizers | [159,160] |
| Piezoelectricity-responsive strategy | Improved conductive characteristics Excellrnt regeneration effect Biocompatibility and non-toxicity | Unfavorable biodegradability Long-term biosafet | [161,162] |
", "bbox": [97, 183, 1092, 577], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "| Type of physical stimuli-responsive strategies | Advantages | Disadvantages | References. |
| Photoresponsive strategy | Noninvasive with high controllability Precise multistaged light program Superior photothermal therapy effects | Low tissue penetration Phototoxicity | [146,147] |
| Electroresponsive strategy | Effective tissue regeneration Improved conductive properties Suitable mechanical properties | Low control precision Undesirable biocompatibility and biodegradability Restricted electrical stimulation | [150,151] |
| Magnetic-responsive strategy | High tissue-penetrating capabilities High control precision | Uncertain biocompatibility and Long-term safety | [154,155] |
| Ultrasound-responsive strategy | Superior tissue penetration depth No drug resistance Non-invasive Cytocompatible; Biocompatible | Low in vivo stability of sonosensitizer drugs Potential toxicity of sonosensitizers | [159,160] |
| Piezoelectricity-responsive strategy | Improved conductive characteristics Excellrnt regeneration effect Biocompatibility and non-toxicity | Unfavorable biodegradability Long-term biosafet | [161,162] |
"}, "layout_signature": {"width": 995, "width_bucket": 1000, "height": 394, "left": 97, "top": 183, "right": 1092, "bottom": 577, "x_center": 594.5, "x_center_bucket": 600, "y_center": 380.0, "x_ratio": 0.4992, "y_ratio": 0.2428, "width_ratio": 0.8354, "height_ratio": 0.2518, "line_count": 1}, "span_signature": {"font_size": 6.97, "font_size_median": 6.97, "font_size_bucket": 7.0, "font_family_norm": "ScalaSansPro-Regular", "bold": false, "italic": true, "span_count": 52}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_139", "display_cluster_candidate_id": "disp_27_0", "layout_region": "display_zone", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.0, "decision": "body", "evidence": []}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"], "asset_family_hint": "table_like", "asset_family_confidence": 0.7, "asset_family_evidence": ["raw_label:table"]}
+{"paper_id": "2HEUD5P9", "page": 17, "block_id": 4, "raw_label": "text", "raw_order": 1, "bbox": [95, 631, 587, 698], "text": "preparation of high-quality tantalum implants, and exploration of breakthrough directions in bone tissue engineering printing technology.", "page_width": 1191, "page_height": 1565, "role": "body_paragraph", "role_confidence": 0.6, "evidence": ["default body_paragraph for text label"], "seed_role": "body_paragraph", "seed_confidence": 0.6, "seed_evidence": ["default body_paragraph for text label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 4, "page": 17, "raw_label": "text", "text": "preparation of high-quality tantalum implants, and exploration of breakthrough directions in bone tissue engineering printing technology.", "bbox": [95, 631, 587, 698], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "preparation of high-quality tantalum implants, and exploration of breakthrough directions in bone tissue engineering printing technology."}, "layout_signature": {"width": 492, "width_bucket": 500, "height": 67, "left": 95, "top": 631, "right": 587, "bottom": 698, "x_center": 341.0, "x_center_bucket": 350, "y_center": 664.5, "x_ratio": 0.2863, "y_ratio": 0.4246, "width_ratio": 0.4131, "height_ratio": 0.0428, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaPro-Regular", "bold": false, "italic": true, "span_count": 29}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_140", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 17, "block_id": 5, "raw_label": "paragraph_title", "raw_order": 2, "bbox": [96, 730, 585, 753], "text": "3.2. Physical Stimuli-Responsive Bone Therapy and Regeneration", "page_width": 1191, "page_height": 1565, "role": "subsection_heading", "role_confidence": 0.85, "evidence": ["paragraph_title label with numbering: 3.2. Physical Stimuli-Responsive Bone Therapy and Regenerati"], "seed_role": "subsection_heading", "seed_confidence": 0.85, "seed_evidence": ["paragraph_title label with numbering: 3.2. Physical Stimuli-Responsive Bone Therapy and Regenerati"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaSansPro-Bold", "flags": 20, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 5, "page": 17, "raw_label": "paragraph_title", "text": "3.2. Physical Stimuli-Responsive Bone Therapy and Regeneration", "bbox": [96, 730, 585, 753], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "heading_numbered", "raw_marker": "3.2", "number": "3.2", "kind": "heading", "normalized_text": "3.2. Physical Stimuli-Responsive Bone Therapy and Regeneration"}, "layout_signature": {"width": 489, "width_bucket": 500, "height": 23, "left": 96, "top": 730, "right": 585, "bottom": 753, "x_center": 340.5, "x_center_bucket": 350, "y_center": 741.5, "x_ratio": 0.2859, "y_ratio": 0.4738, "width_ratio": 0.4106, "height_ratio": 0.0147, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaSansPro-Bold", "bold": true, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_139", "display_cluster_candidate_id": "disp_27_0", "layout_region": "display_zone", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "accepted_heading", "role_evidence": ["heading verified by heading artifact"]}
+{"paper_id": "2HEUD5P9", "page": 17, "block_id": 6, "raw_label": "text", "raw_order": 3, "bbox": [95, 773, 588, 996], "text": "Numerous strategies have been developed to manufacture physical stimuli-responsive materials for bone-tissue engineering. External physical stimuli, including light, magnetic and electric fields, ultrasound, or other proper mechanical stimuli, can affect the atomic arrangements inside materials, thus regulating cell fate and promoting bone-defect repair and regeneration. $ ^{[145]} $ This field has attracted much research attention, and various materials have been manufactured based on these strategies. The advantages and disadvantages of several physical stimuli-responsive strategies are summarized in Table 3.", "page_width": 1191, "page_height": 1565, "role": "body_paragraph", "role_confidence": 0.6, "evidence": ["default body_paragraph for text label"], "seed_role": "body_paragraph", "seed_confidence": 0.6, "seed_evidence": ["default body_paragraph for text label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Bold", "flags": 20, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Bold", "flags": 20, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 6, "page": 17, "raw_label": "text", "text": "Numerous strategies have been developed to manufacture physical stimuli-responsive materials for bone-tissue engineering. External physical stimuli, including light, magnetic and electric fields, ultrasound, or other proper mechanical stimuli, can affect the atomic arrangements inside materials, thus regulating cell fate and promoting bone-defect repair and regeneration. $ ^{[145]} $ This field has attracted much research attention, and various materials have been manufactured based on these strategies. The advantages and disadvantages of several physical stimuli-responsive strategies are summarized in Table 3.", "bbox": [95, 773, 588, 996], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "Numerous strategies have been developed to manufacture physical stimuli-responsive materials for bone-tissue engineering. External physical stimuli, including light, magnetic and electric fields, ultrasound, or other proper mechanical stimuli, can affect the atomic arrangements inside materials, thus regulating cell fate and promoting bone-defect repair and regeneration. $ ^{[145]} $ This field has attracted much research attention, and various materials have been manufactured based on these strategies. The advantages and disadvantages of several physical stimuli-responsive strategies are summarized in Table 3."}, "layout_signature": {"width": 493, "width_bucket": 500, "height": 223, "left": 95, "top": 773, "right": 588, "bottom": 996, "x_center": 341.5, "x_center_bucket": 350, "y_center": 884.5, "x_ratio": 0.2867, "y_ratio": 0.5652, "width_ratio": 0.4139, "height_ratio": 0.1425, "line_count": 1}, "span_signature": {"font_size": 8.85, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaPro-Regular", "bold": true, "italic": true, "span_count": 74}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_140", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 17, "block_id": 7, "raw_label": "paragraph_title", "raw_order": 4, "bbox": [98, 1027, 326, 1049], "text": "3.2.1. Photoresponsive Strategy", "page_width": 1191, "page_height": 1565, "role": "sub_subsection_heading", "role_confidence": 0.85, "evidence": ["paragraph_title label with numbering: 3.2.1. Photoresponsive Strategy"], "seed_role": "sub_subsection_heading", "seed_confidence": 0.85, "seed_evidence": ["paragraph_title label with numbering: 3.2.1. Photoresponsive Strategy"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaSansPro-Italic", "flags": 6, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 7, "page": 17, "raw_label": "paragraph_title", "text": "3.2.1. Photoresponsive Strategy", "bbox": [98, 1027, 326, 1049], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "heading_numbered", "raw_marker": "3.2.1", "number": "3.2.1", "kind": "heading", "normalized_text": "3.2.1. Photoresponsive Strategy"}, "layout_signature": {"width": 228, "width_bucket": 225, "height": 22, "left": 98, "top": 1027, "right": 326, "bottom": 1049, "x_center": 212.0, "x_center_bucket": 200, "y_center": 1038.0, "x_ratio": 0.178, "y_ratio": 0.6633, "width_ratio": 0.1914, "height_ratio": 0.0141, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaSansPro-Italic", "bold": false, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_139", "display_cluster_candidate_id": "disp_27_0", "layout_region": "display_zone", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 17, "block_id": 8, "raw_label": "text", "raw_order": 5, "bbox": [96, 1071, 588, 1445], "text": "Photoresponsive materials can be activated by externally applied optical signals and generate photophysical effects, subsequently affecting intracellular behavior and the respiratory chain, facilitating ATP regeneration of the mitochondrial membrane, enhancing cellular metabolism, and ultimately promoting angiogenesis and bone regeneration.[146] This strategy has attracted considerable research attention and has led to the synthesis of a variety of multifunctional materials owing to the promising outcomes. A completely biodegradable scaffold composed of black phosphorus nanosheets and PLGA showed an efficient near-infrared photothermal effect, even when covered by biological tissue. Upon exposure to near-infrared irradiation, the composite increased the expression of heat shock proteins, ultimately promoting osteogenic differentiation in vitro and in vivo.[147] Similarly, black phosphorus nanosheets-SrCl₂/PLGA microspheres exhibit efficient near-infrared absorption and photothermal responses. Near-infrared light irradiation activates the release of Sr²⁺ by flawing the PLGA shells, ultimately promoting bone regeneration in rat femoral defect models.[148] Under 808-nm near-infrared light irradiation, HAP/graphene oxide/chitosan scaffolds with excellent photothermal conversion properties and osteogenic bioactivity could effectively kill human osteosarcoma cells at 48 °C and facilitate the osteogenic differentiation of MSCs at 42 °C by enhancing the BMP-2/Smad signaling pathway.[149] However, the severe attenuation of light by tissues limits the photothermal conversion performance, thus suppressing bone tissue regeneration. Poor cytotoxicity limits the application of various photoinitiators in tissue engineering.", "page_width": 1191, "page_height": 1565, "role": "body_paragraph", "role_confidence": 0.6, "evidence": ["default body_paragraph for text label"], "seed_role": "body_paragraph", "seed_confidence": 0.6, "seed_evidence": ["default body_paragraph for text label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 8, "page": 17, "raw_label": "text", "text": "Photoresponsive materials can be activated by externally applied optical signals and generate photophysical effects, subsequently affecting intracellular behavior and the respiratory chain, facilitating ATP regeneration of the mitochondrial membrane, enhancing cellular metabolism, and ultimately promoting angiogenesis and bone regeneration.[146] This strategy has attracted considerable research attention and has led to the synthesis of a variety of multifunctional materials owing to the promising outcomes. A completely biodegradable scaffold composed of black phosphorus nanosheets and PLGA showed an efficient near-infrared photothermal effect, even when covered by biological tissue. Upon exposure to near-infrared irradiation, the composite increased the expression of heat shock proteins, ultimately promoting osteogenic differentiation in vitro and in vivo.[147] Similarly, black phosphorus nanosheets-SrCl₂/PLGA microspheres exhibit efficient near-infrared absorption and photothermal responses. Near-infrared light irradiation activates the release of Sr²⁺ by flawing the PLGA shells, ultimately promoting bone regeneration in rat femoral defect models.[148] Under 808-nm near-infrared light irradiation, HAP/graphene oxide/chitosan scaffolds with excellent photothermal conversion properties and osteogenic bioactivity could effectively kill human osteosarcoma cells at 48 °C and facilitate the osteogenic differentiation of MSCs at 42 °C by enhancing the BMP-2/Smad signaling pathway.[149] However, the severe attenuation of light by tissues limits the photothermal conversion performance, thus suppressing bone tissue regeneration. Poor cytotoxicity limits the application of various photoinitiators in tissue engineering.", "bbox": [96, 1071, 588, 1445], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "Photoresponsive materials can be activated by externally applied optical signals and generate photophysical effects, subsequently affecting intracellular behavior and the respiratory chain, facilitating ATP regeneration of the mitochondrial membrane, enhancing cellular metabolism, and ultimately promoting angiogenesis and bone regeneration.[146] This strategy has attracted considerable research attention and has led to the synthesis of a variety of multifunctional materials owing to the promising outcomes. A completely biodegradable scaffold composed of black phosphorus nanosheets and PLGA showed an efficient near-infrared photothermal effect, even when covered by biological tissue. Upon exposure to near-infrared irradiation, the composite increased the expression of heat shock proteins, ultimately promoting osteogenic differentiation in vitro and in vivo.[147] Similarly, black phosphorus nanosheets-SrCl₂/PLGA microspheres exhibit efficient near-infrared absorption and photothermal responses. Near-infrared light irradiation activates the release of Sr²⁺ by flawing the PLGA shells, ultimately promoting bone regeneration in rat femoral defect models.[148] Under 808-nm near-infrared light irradiation, HAP/graphene oxide/chitosan scaffolds with excellent photothermal conversion properties and osteogenic bioactivity could effectively kill human osteosarcoma cells at 48 °C and facilitate the osteogenic differentiation of MSCs at 42 °C by enhancing the BMP-2/Smad signaling pathway.[149] However, the severe attenuation of light by tissues limits the photothermal conversion performance, thus suppressing bone tissue regeneration. Poor cytotoxicity limits the application of various photoinitiators in tissue engineering."}, "layout_signature": {"width": 492, "width_bucket": 500, "height": 374, "left": 96, "top": 1071, "right": 588, "bottom": 1445, "x_center": 342.0, "x_center_bucket": 350, "y_center": 1258.0, "x_ratio": 0.2872, "y_ratio": 0.8038, "width_ratio": 0.4131, "height_ratio": 0.239, "line_count": 1}, "span_signature": {"font_size": 8.84, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaPro-Regular", "bold": false, "italic": true, "span_count": 171}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_140", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 17, "block_id": 9, "raw_label": "text", "raw_order": 6, "bbox": [605, 630, 1098, 876], "text": "", "page_width": 1191, "page_height": 1565, "role": "ocr_text_missing", "role_confidence": 0.8, "evidence": ["ocr detected text region (raw_label=text) but no text extracted; no pdf backfill available"], "seed_role": "ocr_text_missing", "seed_confidence": 0.8, "seed_evidence": ["ocr detected text region (raw_label=text) but no text extracted; no pdf backfill available"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "STIXMath-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "STIX-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "STIX-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "STIX-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 9, "page": 17, "raw_label": "text", "text": "", "bbox": [605, 630, 1098, 876], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "empty", "raw_marker": null, "number": null, "kind": null, "normalized_text": ""}, "layout_signature": {"width": 493, "width_bucket": 500, "height": 246, "left": 605, "top": 630, "right": 1098, "bottom": 876, "x_center": 851.5, "x_center_bucket": 850, "y_center": 753.0, "x_ratio": 0.7149, "y_ratio": 0.4812, "width_ratio": 0.4139, "height_ratio": 0.1572, "line_count": 1}, "span_signature": {"font_size": 8.66, "font_size_median": 8.97, "font_size_bucket": 8.5, "font_family_norm": "ScalaPro-Regular", "bold": false, "italic": true, "span_count": 78}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": "pdf_text_layer_fallback_rejected", "_ocr_raw_status": "missing_text_rejected", "_ocr_raw_error_type": "backfill_overlaps_existing_text_block", "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "_needs_pdf_fallback": true, "reading_band_id": "band_138", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 17, "block_id": 10, "raw_label": "paragraph_title", "raw_order": 7, "bbox": [609, 917, 842, 940], "text": "3.2.2. Electroresponsive Strategy", "page_width": 1191, "page_height": 1565, "role": "sub_subsection_heading", "role_confidence": 0.85, "evidence": ["paragraph_title label with numbering: 3.2.2. Electroresponsive Strategy"], "seed_role": "sub_subsection_heading", "seed_confidence": 0.85, "seed_evidence": ["paragraph_title label with numbering: 3.2.2. Electroresponsive Strategy"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaSansPro-Italic", "flags": 6, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 10, "page": 17, "raw_label": "paragraph_title", "text": "3.2.2. Electroresponsive Strategy", "bbox": [609, 917, 842, 940], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "heading_numbered", "raw_marker": "3.2.2", "number": "3.2.2", "kind": "heading", "normalized_text": "3.2.2. Electroresponsive Strategy"}, "layout_signature": {"width": 233, "width_bucket": 225, "height": 23, "left": 609, "top": 917, "right": 842, "bottom": 940, "x_center": 725.5, "x_center_bucket": 725, "y_center": 928.5, "x_ratio": 0.6092, "y_ratio": 0.5933, "width_ratio": 0.1956, "height_ratio": 0.0147, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaSansPro-Italic", "bold": false, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_141", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "hard", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 17, "block_id": 11, "raw_label": "text", "raw_order": 8, "bbox": [605, 961, 1099, 1445], "text": "Previous studies have shown that electrical stimuli can enhance bone regeneration and maintain the stemness of bone marrow MSCs. The mechanism of this effect is related to the stimulation of MSC proliferation and differentiation by electrical stimulation, which leads to an increased expression of bone morphogenetic proteins. These proteins activate the calcium-calmodulin pathway, TGF- $ \\beta $, and other cytokines, which are involved in bone formation and remodeling. $ ^{[150]} $ One strategy for delivering and responding to localized electrical stimuli is to incorporate electroactive materials, such as metals, carbon nanotubes, graphene, inorganic electroactive materials, and conductive polymers, into biomaterials. These materials modulate cellular activity and improve cell regeneration. Among these electroactive biomaterials, conducting polymers such as polyaniline, polypyrrole, and poly(3,4-ethylenedioxythiophene) have attracted much attention in tissue engineering because of their high conductivities, which are comparable to those of inorganic semiconductor materials and metals, as well as their excellent biocompatibility and ease of manufacturing. $ ^{[151]} $ A cell-affinitive, electroactive, and osteoinductive porous titanium scaffold coated with a polypyrrole-polydopamine-HAP film promoted osteogenic cell differentiation under electrical stimulation. $ ^{[152]} $ When an electrical stimulus", "page_width": 1191, "page_height": 1565, "role": "body_paragraph", "role_confidence": 0.6, "evidence": ["default body_paragraph for text label"], "seed_role": "body_paragraph", "seed_confidence": 0.6, "seed_evidence": ["default body_paragraph for text label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "STIXMath-Italic", "flags": 6, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 11, "page": 17, "raw_label": "text", "text": "Previous studies have shown that electrical stimuli can enhance bone regeneration and maintain the stemness of bone marrow MSCs. The mechanism of this effect is related to the stimulation of MSC proliferation and differentiation by electrical stimulation, which leads to an increased expression of bone morphogenetic proteins. These proteins activate the calcium-calmodulin pathway, TGF- $ \\beta $, and other cytokines, which are involved in bone formation and remodeling. $ ^{[150]} $ One strategy for delivering and responding to localized electrical stimuli is to incorporate electroactive materials, such as metals, carbon nanotubes, graphene, inorganic electroactive materials, and conductive polymers, into biomaterials. These materials modulate cellular activity and improve cell regeneration. Among these electroactive biomaterials, conducting polymers such as polyaniline, polypyrrole, and poly(3,4-ethylenedioxythiophene) have attracted much attention in tissue engineering because of their high conductivities, which are comparable to those of inorganic semiconductor materials and metals, as well as their excellent biocompatibility and ease of manufacturing. $ ^{[151]} $ A cell-affinitive, electroactive, and osteoinductive porous titanium scaffold coated with a polypyrrole-polydopamine-HAP film promoted osteogenic cell differentiation under electrical stimulation. $ ^{[152]} $ When an electrical stimulus", "bbox": [605, 961, 1099, 1445], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "Previous studies have shown that electrical stimuli can enhance bone regeneration and maintain the stemness of bone marrow MSCs. The mechanism of this effect is related to the stimulation of MSC proliferation and differentiation by electrical stimulation, which leads to an increased expression of bone morphogenetic proteins. These proteins activate the calcium-calmodulin pathway, TGF- $ \\beta $, and other cytokines, which are involved in bone formation and remodeling. $ ^{[150]} $ One strategy for delivering and responding to localized electrical stimuli is to incorporate electroactive materials, such as metals, carbon nanotubes, graphene, inorganic electroactive materials, and conductive polymers, into biomaterials. These materials modulate cellular activity and improve cell regeneration. Among these electroactive biomaterials, conducting polymers such as polyaniline, polypyrrole, and poly(3,4-ethylenedioxythiophene) have attracted much attention in tissue engineering because of their high conductivities, which are comparable to those of inorganic semiconductor materials and metals, as well as their excellent biocompatibility and ease of manufacturing. $ ^{[151]} $ A cell-affinitive, electroactive, and osteoinductive porous titanium scaffold coated with a polypyrrole-polydopamine-HAP film promoted osteogenic cell differentiation under electrical stimulation. $ ^{[152]} $ When an electrical stimulus"}, "layout_signature": {"width": 494, "width_bucket": 500, "height": 484, "left": 605, "top": 961, "right": 1099, "bottom": 1445, "x_center": 852.0, "x_center_bucket": 850, "y_center": 1203.0, "x_ratio": 0.7154, "y_ratio": 0.7687, "width_ratio": 0.4148, "height_ratio": 0.3093, "line_count": 1}, "span_signature": {"font_size": 8.82, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaPro-Regular", "bold": false, "italic": true, "span_count": 179}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_142", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 17, "block_id": 12, "raw_label": "footer", "raw_order": null, "bbox": [99, 1487, 289, 1505], "text": "Small Methods 2024, 8, 2301283", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["footer label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["footer label"], "span_metadata": [{"size": 6.973800182342529, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 12, "page": 17, "raw_label": "footer", "text": "Small Methods 2024, 8, 2301283", "bbox": [99, 1487, 289, 1505], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "Small Methods 2024, 8, 2301283"}, "layout_signature": {"width": 190, "width_bucket": 200, "height": 18, "left": 99, "top": 1487, "right": 289, "bottom": 1505, "x_center": 194.0, "x_center_bucket": 200, "y_center": 1496.0, "x_ratio": 0.1629, "y_ratio": 0.9559, "width_ratio": 0.1595, "height_ratio": 0.0115, "line_count": 1}, "span_signature": {"font_size": 6.97, "font_size_median": 6.97, "font_size_bucket": 7.0, "font_family_norm": "ScalaSansPro-Italic", "bold": true, "italic": true, "span_count": 5}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_142", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 17, "block_id": 13, "raw_label": "number", "raw_order": null, "bbox": [526, 1484, 669, 1508], "text": "2301283 (17 of 27)", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["page number label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["page number label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaSansPro-Bold", "flags": 20, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 13, "page": 17, "raw_label": "number", "text": "2301283 (17 of 27)", "bbox": [526, 1484, 669, 1508], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_dot", "raw_marker": "2301283", "number": 2301283, "kind": "reference", "normalized_text": "2301283 (17 of 27)"}, "layout_signature": {"width": 143, "width_bucket": 150, "height": 24, "left": 526, "top": 1484, "right": 669, "bottom": 1508, "x_center": 597.5, "x_center_bucket": 600, "y_center": 1496.0, "x_ratio": 0.5017, "y_ratio": 0.9559, "width_ratio": 0.1201, "height_ratio": 0.0153, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaSansPro-Bold", "bold": true, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "reference_like", "style_family_authority": "reference_family_anchor", "reading_band_id": "band_136", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 17, "block_id": 14, "raw_label": "footer", "raw_order": null, "bbox": [937, 1487, 1096, 1506], "text": "© 2024 Wiley-VCH GmbH", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["footer label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["footer label"], "span_metadata": [{"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 14, "page": 17, "raw_label": "footer", "text": "© 2024 Wiley-VCH GmbH", "bbox": [937, 1487, 1096, 1506], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "© 2024 Wiley-VCH GmbH"}, "layout_signature": {"width": 159, "width_bucket": 150, "height": 19, "left": 937, "top": 1487, "right": 1096, "bottom": 1506, "x_center": 1016.5, "x_center_bucket": 1025, "y_center": 1496.5, "x_ratio": 0.8535, "y_ratio": 0.9562, "width_ratio": 0.1335, "height_ratio": 0.0121, "line_count": 1}, "span_signature": {"font_size": 6.97, "font_size_median": 6.97, "font_size_bucket": 7.0, "font_family_norm": "ScalaSansPro-Regular", "bold": false, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_136", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 17, "block_id": 15, "raw_label": "aside_text", "raw_order": null, "bbox": [1154, 30, 1171, 1534], "text": "23699608, 2024, 8, Downloaded from https://onlinelibrary.wiley.com/doi/10.1002/smkt.202301283 by Shandong University Library, Wiley Online Library on [18/02/2026]. See the Terms and Conditions (https://onlinelibrary.wiley.com/terms-and-conditions) on Wiley Online Library for rules of use; OA articles are governed by the applicable Creative Commons License.", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.95, "evidence": ["margin-band narrow/tall geometry; treated as noise"], "seed_role": "noise", "seed_confidence": 0.95, "seed_evidence": ["margin-band narrow/tall geometry; treated as noise"], "span_metadata": [{"size": 5.03000020980835, "font": "Times-Roman", "flags": 4, "color": 0, "dir": [0.0, 1.0], "wmode": 0}], "raw_observation": {"block_id": 15, "page": 17, "raw_label": "aside_text", "text": "23699608, 2024, 8, Downloaded from https://onlinelibrary.wiley.com/doi/10.1002/smkt.202301283 by Shandong University Library, Wiley Online Library on [18/02/2026]. See the Terms and Conditions (https://onlinelibrary.wiley.com/terms-and-conditions) on Wiley Online Library for rules of use; OA articles are governed by the applicable Creative Commons License.", "bbox": [1154, 30, 1171, 1534], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "23699608, 2024, 8, Downloaded from https://onlinelibrary.wiley.com/doi/10.1002/smkt.202301283 by Shandong University Library, Wiley Online Library on [18/02/2026]. See the Terms and Conditions (https://onlinelibrary.wiley.com/terms-and-conditions) on Wiley Online Library for rules of use; OA articles are governed by the applicable Creative Commons License."}, "layout_signature": {"width": 17, "width_bucket": 25, "height": 1504, "left": 1154, "top": 30, "right": 1171, "bottom": 1534, "x_center": 1162.5, "x_center_bucket": 1150, "y_center": 782.0, "x_ratio": 0.9761, "y_ratio": 0.4997, "width_ratio": 0.0143, "height_ratio": 0.961, "line_count": 1}, "span_signature": {"font_size": 5.03, "font_size_median": 5.03, "font_size_bucket": 5.0, "font_family_norm": "Times-Roman", "bold": false, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_family_anchor", "reading_band_id": "band_136", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 18, "block_id": 0, "raw_label": "header", "raw_order": null, "bbox": [92, 46, 339, 117], "text": "ADVANCED\nSCIENCE NEWS\nwww.advancedsciencenews.com", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["header label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["header label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaSansPro-Bold", "flags": 20, "color": 255, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 0, "page": 18, "raw_label": "header", "text": "ADVANCED\nSCIENCE NEWS\nwww.advancedsciencenews.com", "bbox": [92, 46, 339, 117], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "ADVANCED\nSCIENCE NEWS\nwww.advancedsciencenews.com"}, "layout_signature": {"width": 247, "width_bucket": 250, "height": 71, "left": 92, "top": 46, "right": 339, "bottom": 117, "x_center": 215.5, "x_center_bucket": 225, "y_center": 81.5, "x_ratio": 0.1809, "y_ratio": 0.0521, "width_ratio": 0.2074, "height_ratio": 0.0454, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaSansPro-Bold", "bold": true, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 18, "block_id": 1, "raw_label": "header", "raw_order": null, "bbox": [997, 36, 1089, 96], "text": "small methods", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["header label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["header label"], "span_metadata": null, "raw_observation": {"block_id": 1, "page": 18, "raw_label": "header", "text": "small methods", "bbox": [997, 36, 1089, 96], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "short_fragment", "raw_marker": "small methods", "number": null, "kind": "short_fragment", "normalized_text": "small methods"}, "layout_signature": {"width": 92, "width_bucket": 100, "height": 60, "left": 997, "top": 36, "right": 1089, "bottom": 96, "x_center": 1043.0, "x_center_bucket": 1050, "y_center": 66.0, "x_ratio": 0.8757, "y_ratio": 0.0422, "width_ratio": 0.0772, "height_ratio": 0.0383, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": true, "_container_bbox": [1000.0802235557833, 37.836628863963085, 1078.3616835103696, 91.04600210547972], "_container_text": "small methods", "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_142", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.6, "decision": "structured_insert_candidate", "evidence": ["visual_container", "narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 18, "block_id": 2, "raw_label": "header", "raw_order": null, "bbox": [897, 97, 1090, 117], "text": "www.small-methods.com", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["header label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["header label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaSansPro-Bold", "flags": 20, "color": 255, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 2, "page": 18, "raw_label": "header", "text": "www.small-methods.com", "bbox": [897, 97, 1090, 117], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "www.small-methods.com"}, "layout_signature": {"width": 193, "width_bucket": 200, "height": 20, "left": 897, "top": 97, "right": 1090, "bottom": 117, "x_center": 993.5, "x_center_bucket": 1000, "y_center": 107.0, "x_ratio": 0.8342, "y_ratio": 0.0684, "width_ratio": 0.162, "height_ratio": 0.0128, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaSansPro-Bold", "bold": true, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_142", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 18, "block_id": 3, "raw_label": "text", "raw_order": 1, "bbox": [90, 148, 581, 436], "text": "was applied, titanium sheets coated with polyaniline (poly(amide-amine) dendrimer) @ Ag layer exhibited excellent antibacterial properties and improved osteogenic differentiation compared with pure titanium.[151] Electroactive GdPO₄H₂O/poly(3-hexylthiophene)/PLGA nanocomposites enhanced ALP activity, calcium deposition, and the expression of osteogenic genes under electrical stimuli at 100 Hz and 500 mV.[153] Conductive scaffolds face challenges regarding their long-term performance in vivo, such as biocompatibility and biodegradability. These aspects need to be investigated further because of their prolonged presence in vivo. Nevertheless, we are optimistic that conductive bio-materials will emerge as promising new tissue engineering materials.", "page_width": 1191, "page_height": 1565, "role": "body_paragraph", "role_confidence": 0.6, "evidence": ["default body_paragraph for text label"], "seed_role": "body_paragraph", "seed_confidence": 0.6, "seed_evidence": ["default body_paragraph for text label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 3, "page": 18, "raw_label": "text", "text": "was applied, titanium sheets coated with polyaniline (poly(amide-amine) dendrimer) @ Ag layer exhibited excellent antibacterial properties and improved osteogenic differentiation compared with pure titanium.[151] Electroactive GdPO₄H₂O/poly(3-hexylthiophene)/PLGA nanocomposites enhanced ALP activity, calcium deposition, and the expression of osteogenic genes under electrical stimuli at 100 Hz and 500 mV.[153] Conductive scaffolds face challenges regarding their long-term performance in vivo, such as biocompatibility and biodegradability. These aspects need to be investigated further because of their prolonged presence in vivo. Nevertheless, we are optimistic that conductive bio-materials will emerge as promising new tissue engineering materials.", "bbox": [90, 148, 581, 436], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "was applied, titanium sheets coated with polyaniline (poly(amide-amine) dendrimer) @ Ag layer exhibited excellent antibacterial properties and improved osteogenic differentiation compared with pure titanium.[151] Electroactive GdPO₄H₂O/poly(3-hexylthiophene)/PLGA nanocomposites enhanced ALP activity, calcium deposition, and the expression of osteogenic genes under electrical stimuli at 100 Hz and 500 mV.[153] Conductive scaffolds face challenges regarding their long-term performance in vivo, such as biocompatibility and biodegradability. These aspects need to be investigated further because of their prolonged presence in vivo. Nevertheless, we are optimistic that conductive bio-materials will emerge as promising new tissue engineering materials."}, "layout_signature": {"width": 491, "width_bucket": 500, "height": 288, "left": 90, "top": 148, "right": 581, "bottom": 436, "x_center": 335.5, "x_center_bucket": 325, "y_center": 292.0, "x_ratio": 0.2817, "y_ratio": 0.1866, "width_ratio": 0.4123, "height_ratio": 0.184, "line_count": 1}, "span_signature": {"font_size": 8.68, "font_size_median": 8.97, "font_size_bucket": 8.5, "font_family_norm": "ScalaPro-Regular", "bold": false, "italic": true, "span_count": 83}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_139", "display_cluster_candidate_id": "disp_27_0", "layout_region": "display_zone", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "zone": "body_zone", "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 18, "block_id": 4, "raw_label": "paragraph_title", "raw_order": 2, "bbox": [92, 478, 354, 501], "text": "3.2.3. Magnetic-Responsive Strategy", "page_width": 1191, "page_height": 1565, "role": "sub_subsection_heading", "role_confidence": 0.85, "evidence": ["paragraph_title label with numbering: 3.2.3. Magnetic-Responsive Strategy"], "seed_role": "sub_subsection_heading", "seed_confidence": 0.85, "seed_evidence": ["paragraph_title label with numbering: 3.2.3. Magnetic-Responsive Strategy"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaSansPro-Italic", "flags": 6, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 4, "page": 18, "raw_label": "paragraph_title", "text": "3.2.3. Magnetic-Responsive Strategy", "bbox": [92, 478, 354, 501], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "heading_numbered", "raw_marker": "3.2.3", "number": "3.2.3", "kind": "heading", "normalized_text": "3.2.3. Magnetic-Responsive Strategy"}, "layout_signature": {"width": 262, "width_bucket": 250, "height": 23, "left": 92, "top": 478, "right": 354, "bottom": 501, "x_center": 223.0, "x_center_bucket": 225, "y_center": 489.5, "x_ratio": 0.1872, "y_ratio": 0.3128, "width_ratio": 0.22, "height_ratio": 0.0147, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaSansPro-Italic", "bold": false, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_140", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "zone": "body_zone", "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 18, "block_id": 5, "raw_label": "text", "raw_order": 3, "bbox": [89, 519, 583, 1315], "text": "Magnetic-responsive materials are composed of ferromagnetic or paramagnetic nanoparticles that can be manipulated by magnetic fields and act as therapeutic agents for magnetic hyperthermia. Magnetic nanoparticles, such as Fe₃O₄ nanoparticles, can produce heat under magnetic fields and enhance the osteogenic differentiation capability.[154] Therefore, this technology has significant potential for repairing bone defects. Magnetic Fe₃O₄ nanoparticles can generate heat under magnetic fields and raise the temperature to 42–45 °C, thus promoting apoptosis and death of cancer cells by causing hemorrhage or vascular occlusion without affecting nearby normal tissues. Moreover, although the underlying mechanisms are complex, magnetic hyperthermia may promote osteogenesis. Some studies have proposed that hyperthermia affects bone metabolism by increasing blood supply, while others have argued that hyperthermia enhances osteogenesis by boosting mitochondrial activity and the expression of osteogenic markers.[155] The specific mechanisms of osteogenic stimulation by magnetic hyperthermia require further clarification. Magnetothermal therapy under magnetic fields has the merit of high tissue penetration and is suitable for the treatment of lesions in deep tissues. Magnetic field-responsive strategies have been employed to develop versatile materials for bone repair and regeneration. The AKT-Fe₃O₄-CaO₂ composite scaffold triggered magnetic hyperthermia for rapid heating and the Fenton reaction in tumor oxidative therapy. The loaded CaO₂ nanoparticles generated H₂O₂, compensated for H₂O₂ consumption via the Fenton reaction, and sustainably released Ca²⁺ ions to promote osteogenesis.[156] α-TCP/calcium sulfate biphasic bone cement combined with Fe₃O₄/graphene oxide showed an outstanding magnetothermal effect, improved the effect of tumor treatment, and facilitated cell proliferation, adhesion, and osteogenic differentiation.[157] However, the field of bone therapy and regeneration induced by magnetic stimulation is still in its infancy. Future studies may focus on homogeneous temperature elevation by magnetic stimuli and develop strategies to minimize thermal injury to adjacent normal tissues.", "page_width": 1191, "page_height": 1565, "role": "body_paragraph", "role_confidence": 0.6, "evidence": ["default body_paragraph for text label"], "seed_role": "body_paragraph", "seed_confidence": 0.6, "seed_evidence": ["default body_paragraph for text label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "STIX-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "STIX-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "STIXMath-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "STIXMath-Italic", "flags": 7, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "STIXMath-Italic", "flags": 6, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 5, "page": 18, "raw_label": "text", "text": "Magnetic-responsive materials are composed of ferromagnetic or paramagnetic nanoparticles that can be manipulated by magnetic fields and act as therapeutic agents for magnetic hyperthermia. Magnetic nanoparticles, such as Fe₃O₄ nanoparticles, can produce heat under magnetic fields and enhance the osteogenic differentiation capability.[154] Therefore, this technology has significant potential for repairing bone defects. Magnetic Fe₃O₄ nanoparticles can generate heat under magnetic fields and raise the temperature to 42–45 °C, thus promoting apoptosis and death of cancer cells by causing hemorrhage or vascular occlusion without affecting nearby normal tissues. Moreover, although the underlying mechanisms are complex, magnetic hyperthermia may promote osteogenesis. Some studies have proposed that hyperthermia affects bone metabolism by increasing blood supply, while others have argued that hyperthermia enhances osteogenesis by boosting mitochondrial activity and the expression of osteogenic markers.[155] The specific mechanisms of osteogenic stimulation by magnetic hyperthermia require further clarification. Magnetothermal therapy under magnetic fields has the merit of high tissue penetration and is suitable for the treatment of lesions in deep tissues. Magnetic field-responsive strategies have been employed to develop versatile materials for bone repair and regeneration. The AKT-Fe₃O₄-CaO₂ composite scaffold triggered magnetic hyperthermia for rapid heating and the Fenton reaction in tumor oxidative therapy. The loaded CaO₂ nanoparticles generated H₂O₂, compensated for H₂O₂ consumption via the Fenton reaction, and sustainably released Ca²⁺ ions to promote osteogenesis.[156] α-TCP/calcium sulfate biphasic bone cement combined with Fe₃O₄/graphene oxide showed an outstanding magnetothermal effect, improved the effect of tumor treatment, and facilitated cell proliferation, adhesion, and osteogenic differentiation.[157] However, the field of bone therapy and regeneration induced by magnetic stimulation is still in its infancy. Future studies may focus on homogeneous temperature elevation by magnetic stimuli and develop strategies to minimize thermal injury to adjacent normal tissues.", "bbox": [89, 519, 583, 1315], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "Magnetic-responsive materials are composed of ferromagnetic or paramagnetic nanoparticles that can be manipulated by magnetic fields and act as therapeutic agents for magnetic hyperthermia. Magnetic nanoparticles, such as Fe₃O₄ nanoparticles, can produce heat under magnetic fields and enhance the osteogenic differentiation capability.[154] Therefore, this technology has significant potential for repairing bone defects. Magnetic Fe₃O₄ nanoparticles can generate heat under magnetic fields and raise the temperature to 42–45 °C, thus promoting apoptosis and death of cancer cells by causing hemorrhage or vascular occlusion without affecting nearby normal tissues. Moreover, although the underlying mechanisms are complex, magnetic hyperthermia may promote osteogenesis. Some studies have proposed that hyperthermia affects bone metabolism by increasing blood supply, while others have argued that hyperthermia enhances osteogenesis by boosting mitochondrial activity and the expression of osteogenic markers.[155] The specific mechanisms of osteogenic stimulation by magnetic hyperthermia require further clarification. Magnetothermal therapy under magnetic fields has the merit of high tissue penetration and is suitable for the treatment of lesions in deep tissues. Magnetic field-responsive strategies have been employed to develop versatile materials for bone repair and regeneration. The AKT-Fe₃O₄-CaO₂ composite scaffold triggered magnetic hyperthermia for rapid heating and the Fenton reaction in tumor oxidative therapy. The loaded CaO₂ nanoparticles generated H₂O₂, compensated for H₂O₂ consumption via the Fenton reaction, and sustainably released Ca²⁺ ions to promote osteogenesis.[156] α-TCP/calcium sulfate biphasic bone cement combined with Fe₃O₄/graphene oxide showed an outstanding magnetothermal effect, improved the effect of tumor treatment, and facilitated cell proliferation, adhesion, and osteogenic differentiation.[157] However, the field of bone therapy and regeneration induced by magnetic stimulation is still in its infancy. Future studies may focus on homogeneous temperature elevation by magnetic stimuli and develop strategies to minimize thermal injury to adjacent normal tissues."}, "layout_signature": {"width": 494, "width_bucket": 500, "height": 796, "left": 89, "top": 519, "right": 583, "bottom": 1315, "x_center": 336.0, "x_center_bucket": 325, "y_center": 917.0, "x_ratio": 0.2821, "y_ratio": 0.5859, "width_ratio": 0.4148, "height_ratio": 0.5086, "line_count": 1}, "span_signature": {"font_size": 8.74, "font_size_median": 8.97, "font_size_bucket": 8.5, "font_family_norm": "ScalaPro-Regular", "bold": false, "italic": true, "span_count": 377}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_139", "display_cluster_candidate_id": "disp_27_0", "layout_region": "display_zone", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "zone": "body_zone", "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 18, "block_id": 6, "raw_label": "paragraph_title", "raw_order": 4, "bbox": [92, 1355, 367, 1379], "text": "3.2.4. Ultrasound-Responsive Strategy", "page_width": 1191, "page_height": 1565, "role": "sub_subsection_heading", "role_confidence": 0.85, "evidence": ["paragraph_title label with numbering: 3.2.4. Ultrasound-Responsive Strategy"], "seed_role": "sub_subsection_heading", "seed_confidence": 0.85, "seed_evidence": ["paragraph_title label with numbering: 3.2.4. Ultrasound-Responsive Strategy"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaSansPro-Italic", "flags": 6, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 6, "page": 18, "raw_label": "paragraph_title", "text": "3.2.4. Ultrasound-Responsive Strategy", "bbox": [92, 1355, 367, 1379], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "heading_numbered", "raw_marker": "3.2.4", "number": "3.2.4", "kind": "heading", "normalized_text": "3.2.4. Ultrasound-Responsive Strategy"}, "layout_signature": {"width": 275, "width_bucket": 275, "height": 24, "left": 92, "top": 1355, "right": 367, "bottom": 1379, "x_center": 229.5, "x_center_bucket": 225, "y_center": 1367.0, "x_ratio": 0.1927, "y_ratio": 0.8735, "width_ratio": 0.2309, "height_ratio": 0.0153, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaSansPro-Italic", "bold": false, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_140", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "zone": "body_zone", "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 18, "block_id": 7, "raw_label": "text", "raw_order": 5, "bbox": [90, 1398, 582, 1445], "text": "Ultrasound has been shown to promote bone regeneration by increasing the mRNA expression of VEGF-A and stimulating the proliferation of chondrocytes, thereby facilitating the formation of new bone and cell mineralization (Figure 7A–C).[158] Nanocomplexes can be triggered by nonthermal clinical diagnostic ultrasound to release liposome-recombinant human bone morphogenetic protein 2 (rhBMP-2). When implanted into hind limb muscles, the nanocomplexes initiated local bone formation only upon ultrasound stimulation. Furthermore, the release behavior of rhBMP-2 was associated with ultrasound pressure and exposure duration.[159] A sulfur-doped titanium implant possesses highly efficient antibacterial properties against Staphylococcus aureus under near-infrared light and ultrasound stimulation. The combined therapy effectively cured severe bone infections and enhanced osseointegration.[160] The ultrasound-responsive strategy, which is similar as the photoresponsive strategy, is noninvasive and highly controllable. Furthermore, this strategy has superior tissue penetration compared with conventional laser exposure for the treatment of diseases deep within the body.", "page_width": 1191, "page_height": 1565, "role": "body_paragraph", "role_confidence": 0.6, "evidence": ["default body_paragraph for text label"], "seed_role": "body_paragraph", "seed_confidence": 0.6, "seed_evidence": ["default body_paragraph for text label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 7, "page": 18, "raw_label": "text", "text": "Ultrasound has been shown to promote bone regeneration by increasing the mRNA expression of VEGF-A and stimulating the proliferation of chondrocytes, thereby facilitating the formation of new bone and cell mineralization (Figure 7A–C).[158] Nanocomplexes can be triggered by nonthermal clinical diagnostic ultrasound to release liposome-recombinant human bone morphogenetic protein 2 (rhBMP-2). When implanted into hind limb muscles, the nanocomplexes initiated local bone formation only upon ultrasound stimulation. Furthermore, the release behavior of rhBMP-2 was associated with ultrasound pressure and exposure duration.[159] A sulfur-doped titanium implant possesses highly efficient antibacterial properties against Staphylococcus aureus under near-infrared light and ultrasound stimulation. The combined therapy effectively cured severe bone infections and enhanced osseointegration.[160] The ultrasound-responsive strategy, which is similar as the photoresponsive strategy, is noninvasive and highly controllable. Furthermore, this strategy has superior tissue penetration compared with conventional laser exposure for the treatment of diseases deep within the body.", "bbox": [90, 1398, 582, 1445], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "Ultrasound has been shown to promote bone regeneration by increasing the mRNA expression of VEGF-A and stimulating the proliferation of chondrocytes, thereby facilitating the formation of new bone and cell mineralization (Figure 7A–C).[158] Nanocomplexes can be triggered by nonthermal clinical diagnostic ultrasound to release liposome-recombinant human bone morphogenetic protein 2 (rhBMP-2). When implanted into hind limb muscles, the nanocomplexes initiated local bone formation only upon ultrasound stimulation. Furthermore, the release behavior of rhBMP-2 was associated with ultrasound pressure and exposure duration.[159] A sulfur-doped titanium implant possesses highly efficient antibacterial properties against Staphylococcus aureus under near-infrared light and ultrasound stimulation. The combined therapy effectively cured severe bone infections and enhanced osseointegration.[160] The ultrasound-responsive strategy, which is similar as the photoresponsive strategy, is noninvasive and highly controllable. Furthermore, this strategy has superior tissue penetration compared with conventional laser exposure for the treatment of diseases deep within the body."}, "layout_signature": {"width": 492, "width_bucket": 500, "height": 47, "left": 90, "top": 1398, "right": 582, "bottom": 1445, "x_center": 336.0, "x_center_bucket": 325, "y_center": 1421.5, "x_ratio": 0.2821, "y_ratio": 0.9083, "width_ratio": 0.4131, "height_ratio": 0.03, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaPro-Regular", "bold": false, "italic": true, "span_count": 32}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_139", "display_cluster_candidate_id": "disp_27_0", "layout_region": "display_zone", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "zone": "body_zone", "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 18, "block_id": 8, "raw_label": "text", "raw_order": 6, "bbox": [600, 149, 1093, 545], "text": "", "page_width": 1191, "page_height": 1565, "role": "ocr_text_missing", "role_confidence": 0.8, "evidence": ["ocr detected text region (raw_label=text) but no text extracted; no pdf backfill available"], "seed_role": "ocr_text_missing", "seed_confidence": 0.8, "seed_evidence": ["ocr detected text region (raw_label=text) but no text extracted; no pdf backfill available"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Bold", "flags": 20, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Bold", "flags": 20, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Bold", "flags": 20, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Italic", "flags": 6, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Italic", "flags": 6, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Italic", "flags": 6, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 8, "page": 18, "raw_label": "text", "text": "", "bbox": [600, 149, 1093, 545], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "empty", "raw_marker": null, "number": null, "kind": null, "normalized_text": ""}, "layout_signature": {"width": 493, "width_bucket": 500, "height": 396, "left": 600, "top": 149, "right": 1093, "bottom": 545, "x_center": 846.5, "x_center_bucket": 850, "y_center": 347.0, "x_ratio": 0.7107, "y_ratio": 0.2217, "width_ratio": 0.4139, "height_ratio": 0.253, "line_count": 1}, "span_signature": {"font_size": 8.82, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaPro-Regular", "bold": true, "italic": true, "span_count": 182}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": "pdf_text_layer_fallback_rejected", "_ocr_raw_status": "missing_text_rejected", "_ocr_raw_error_type": "backfill_overlaps_existing_text_block", "render_default": true, "index_default": true, "style_family": "unknown_like", "style_family_authority": "fallback", "_needs_pdf_fallback": true, "reading_band_id": "band_140", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 18, "block_id": 9, "raw_label": "paragraph_title", "raw_order": 7, "bbox": [602, 588, 902, 611], "text": "3.2.5. Piezoelectricity-Responsive Strategy", "page_width": 1191, "page_height": 1565, "role": "sub_subsection_heading", "role_confidence": 0.85, "evidence": ["paragraph_title label with numbering: 3.2.5. Piezoelectricity-Responsive Strategy"], "seed_role": "sub_subsection_heading", "seed_confidence": 0.85, "seed_evidence": ["paragraph_title label with numbering: 3.2.5. Piezoelectricity-Responsive Strategy"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaSansPro-Italic", "flags": 6, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 9, "page": 18, "raw_label": "paragraph_title", "text": "3.2.5. Piezoelectricity-Responsive Strategy", "bbox": [602, 588, 902, 611], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "heading_numbered", "raw_marker": "3.2.5", "number": "3.2.5", "kind": "heading", "normalized_text": "3.2.5. Piezoelectricity-Responsive Strategy"}, "layout_signature": {"width": 300, "width_bucket": 300, "height": 23, "left": 602, "top": 588, "right": 902, "bottom": 611, "x_center": 752.0, "x_center_bucket": 750, "y_center": 599.5, "x_ratio": 0.6314, "y_ratio": 0.3831, "width_ratio": 0.2519, "height_ratio": 0.0147, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaSansPro-Italic", "bold": false, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_138", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "zone": "body_zone", "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 18, "block_id": 10, "raw_label": "text", "raw_order": 8, "bbox": [598, 632, 1094, 1445], "text": "Natural bone tissues exhibit bioelectrical properties that are essential for bone development. Piezoelectricity is the conversion of mechanical energy into electrical energy. Under physiological conditions, bones produce electrical signals when subjected to mechanical stimuli, ultimately stimulating bone regeneration. Piezoelectricity modulates cellular functions and enhances cell proliferation and osteogenesis. $ ^{[161]} $ Various piezoelectric biomaterials such as piezo-bioceramics and piezo-biopolymers have been extensively applied in bone tissue engineering. HAP/barium titanate piezoelectric composites affected by cyclic loading promoted the proliferation of osteoblasts and their interaction with HA compared to pure HAP. $ ^{[162]} $ Polarized barium titanate/poly(vinylidene fluoride trifluoroethylene) nanocomposite membranes enhanced osteoinductivity and accelerated neovascularization. In addition, the composite combined with xenogeneic grafts of deproteinized bovine bone promoted mature bone structure formation within critically sized mandibular defects in rabbits. $ ^{[163]} $ A scaffold that mimics the structure and function of the periosteum by rationally combining poly(vinylidene fluoride-trifluoroethylene) (PVFT) and BGs significantly promoted cell proliferation, adhesion, and osteogenesis and facilitated periosteum-like tissue formation and critical-sized bone regeneration. Furthermore, the negative pole of PVFT attracts Ca $ ^{2+} $ from BGs, activating the calcium-sensing receptor of osteoblasts, thereby promoting osteogenesis. $ ^{[164]} $ 3D-printed acrylate epoxidized soybean oil (AESO) doped with Ag-TMSPM-pBT (ATP) piezoelectric scaffolds (AESO-ATP scaffolds) exhibited superior piezoelectric properties, close to the piezoelectric constants of bone tissue. Furthermore, this composite scaffolds facilitated osteogenic differentiation of BMSCs in vitro, and repaired bone defect in vivo. $ ^{[165]} $ However, piezoelectricity-responsive strategies have challenges such as the effects of densification, alkali evaporation, and high temperatures in the synthetic procedure, which remain to be solved. The underlying mechanisms and long-term biological safety of piezoelectricity-responsive materials should be investigated in future studies. Triboelectric stimulation technology is used to achieve bone repair via mechanosensation of", "page_width": 1191, "page_height": 1565, "role": "body_paragraph", "role_confidence": 0.6, "evidence": ["default body_paragraph for text label"], "seed_role": "body_paragraph", "seed_confidence": 0.6, "seed_evidence": ["default body_paragraph for text label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "STIXMath-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 10, "page": 18, "raw_label": "text", "text": "Natural bone tissues exhibit bioelectrical properties that are essential for bone development. Piezoelectricity is the conversion of mechanical energy into electrical energy. Under physiological conditions, bones produce electrical signals when subjected to mechanical stimuli, ultimately stimulating bone regeneration. Piezoelectricity modulates cellular functions and enhances cell proliferation and osteogenesis. $ ^{[161]} $ Various piezoelectric biomaterials such as piezo-bioceramics and piezo-biopolymers have been extensively applied in bone tissue engineering. HAP/barium titanate piezoelectric composites affected by cyclic loading promoted the proliferation of osteoblasts and their interaction with HA compared to pure HAP. $ ^{[162]} $ Polarized barium titanate/poly(vinylidene fluoride trifluoroethylene) nanocomposite membranes enhanced osteoinductivity and accelerated neovascularization. In addition, the composite combined with xenogeneic grafts of deproteinized bovine bone promoted mature bone structure formation within critically sized mandibular defects in rabbits. $ ^{[163]} $ A scaffold that mimics the structure and function of the periosteum by rationally combining poly(vinylidene fluoride-trifluoroethylene) (PVFT) and BGs significantly promoted cell proliferation, adhesion, and osteogenesis and facilitated periosteum-like tissue formation and critical-sized bone regeneration. Furthermore, the negative pole of PVFT attracts Ca $ ^{2+} $ from BGs, activating the calcium-sensing receptor of osteoblasts, thereby promoting osteogenesis. $ ^{[164]} $ 3D-printed acrylate epoxidized soybean oil (AESO) doped with Ag-TMSPM-pBT (ATP) piezoelectric scaffolds (AESO-ATP scaffolds) exhibited superior piezoelectric properties, close to the piezoelectric constants of bone tissue. Furthermore, this composite scaffolds facilitated osteogenic differentiation of BMSCs in vitro, and repaired bone defect in vivo. $ ^{[165]} $ However, piezoelectricity-responsive strategies have challenges such as the effects of densification, alkali evaporation, and high temperatures in the synthetic procedure, which remain to be solved. The underlying mechanisms and long-term biological safety of piezoelectricity-responsive materials should be investigated in future studies. Triboelectric stimulation technology is used to achieve bone repair via mechanosensation of", "bbox": [598, 632, 1094, 1445], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "Natural bone tissues exhibit bioelectrical properties that are essential for bone development. Piezoelectricity is the conversion of mechanical energy into electrical energy. Under physiological conditions, bones produce electrical signals when subjected to mechanical stimuli, ultimately stimulating bone regeneration. Piezoelectricity modulates cellular functions and enhances cell proliferation and osteogenesis. $ ^{[161]} $ Various piezoelectric biomaterials such as piezo-bioceramics and piezo-biopolymers have been extensively applied in bone tissue engineering. HAP/barium titanate piezoelectric composites affected by cyclic loading promoted the proliferation of osteoblasts and their interaction with HA compared to pure HAP. $ ^{[162]} $ Polarized barium titanate/poly(vinylidene fluoride trifluoroethylene) nanocomposite membranes enhanced osteoinductivity and accelerated neovascularization. In addition, the composite combined with xenogeneic grafts of deproteinized bovine bone promoted mature bone structure formation within critically sized mandibular defects in rabbits. $ ^{[163]} $ A scaffold that mimics the structure and function of the periosteum by rationally combining poly(vinylidene fluoride-trifluoroethylene) (PVFT) and BGs significantly promoted cell proliferation, adhesion, and osteogenesis and facilitated periosteum-like tissue formation and critical-sized bone regeneration. Furthermore, the negative pole of PVFT attracts Ca $ ^{2+} $ from BGs, activating the calcium-sensing receptor of osteoblasts, thereby promoting osteogenesis. $ ^{[164]} $ 3D-printed acrylate epoxidized soybean oil (AESO) doped with Ag-TMSPM-pBT (ATP) piezoelectric scaffolds (AESO-ATP scaffolds) exhibited superior piezoelectric properties, close to the piezoelectric constants of bone tissue. Furthermore, this composite scaffolds facilitated osteogenic differentiation of BMSCs in vitro, and repaired bone defect in vivo. $ ^{[165]} $ However, piezoelectricity-responsive strategies have challenges such as the effects of densification, alkali evaporation, and high temperatures in the synthetic procedure, which remain to be solved. The underlying mechanisms and long-term biological safety of piezoelectricity-responsive materials should be investigated in future studies. Triboelectric stimulation technology is used to achieve bone repair via mechanosensation of"}, "layout_signature": {"width": 496, "width_bucket": 500, "height": 813, "left": 598, "top": 632, "right": 1094, "bottom": 1445, "x_center": 846.0, "x_center_bucket": 850, "y_center": 1038.5, "x_ratio": 0.7103, "y_ratio": 0.6636, "width_ratio": 0.4165, "height_ratio": 0.5195, "line_count": 1}, "span_signature": {"font_size": 8.82, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaPro-Regular", "bold": false, "italic": true, "span_count": 352}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_141", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "hard", "boundary_after": "none", "bridge_eligible": false, "zone": "body_zone", "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 18, "block_id": 11, "raw_label": "footer", "raw_order": null, "bbox": [94, 1487, 283, 1505], "text": "Small Methods 2024, 8, 2301283", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["footer label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["footer label"], "span_metadata": [{"size": 6.973800182342529, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 11, "page": 18, "raw_label": "footer", "text": "Small Methods 2024, 8, 2301283", "bbox": [94, 1487, 283, 1505], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "Small Methods 2024, 8, 2301283"}, "layout_signature": {"width": 189, "width_bucket": 200, "height": 18, "left": 94, "top": 1487, "right": 283, "bottom": 1505, "x_center": 188.5, "x_center_bucket": 200, "y_center": 1496.0, "x_ratio": 0.1583, "y_ratio": 0.9559, "width_ratio": 0.1587, "height_ratio": 0.0115, "line_count": 1}, "span_signature": {"font_size": 6.97, "font_size_median": 6.97, "font_size_bucket": 7.0, "font_family_norm": "ScalaSansPro-Italic", "bold": true, "italic": true, "span_count": 5}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_142", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 18, "block_id": 12, "raw_label": "footer", "raw_order": null, "bbox": [520, 1484, 663, 1507], "text": "2301283 (18 of 27)", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.9, "evidence": ["footer label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["footer label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaSansPro-Bold", "flags": 20, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 12, "page": 18, "raw_label": "footer", "text": "2301283 (18 of 27)", "bbox": [520, 1484, 663, 1507], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_dot", "raw_marker": "2301283", "number": 2301283, "kind": "reference", "normalized_text": "2301283 (18 of 27)"}, "layout_signature": {"width": 143, "width_bucket": 150, "height": 23, "left": 520, "top": 1484, "right": 663, "bottom": 1507, "x_center": 591.5, "x_center_bucket": 600, "y_center": 1495.5, "x_ratio": 0.4966, "y_ratio": 0.9556, "width_ratio": 0.1201, "height_ratio": 0.0147, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaSansPro-Bold", "bold": true, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_family_anchor", "reading_band_id": "band_142", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 18, "block_id": 13, "raw_label": "footer", "raw_order": null, "bbox": [931, 1487, 1090, 1506], "text": "© 2024 Wiley-VCH GmbH", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["footer label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["footer label"], "span_metadata": [{"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 13, "page": 18, "raw_label": "footer", "text": "© 2024 Wiley-VCH GmbH", "bbox": [931, 1487, 1090, 1506], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "© 2024 Wiley-VCH GmbH"}, "layout_signature": {"width": 159, "width_bucket": 150, "height": 19, "left": 931, "top": 1487, "right": 1090, "bottom": 1506, "x_center": 1010.5, "x_center_bucket": 1000, "y_center": 1496.5, "x_ratio": 0.8484, "y_ratio": 0.9562, "width_ratio": 0.1335, "height_ratio": 0.0121, "line_count": 1}, "span_signature": {"font_size": 6.97, "font_size_median": 6.97, "font_size_bucket": 7.0, "font_family_norm": "ScalaSansPro-Regular", "bold": false, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_136", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 18, "block_id": 14, "raw_label": "aside_text", "raw_order": null, "bbox": [1153, 22, 1171, 1533], "text": "23669608, 2024, 8, Downloaded from https://onlinelibrary.wiley.com/doi/10.1002/smkl.202301283 by Shandong University Library, Wiley Online Library on [18/02/2026]. See the Terms and Conditions (https://onlinelibrary.wiley.com/terms-and-conditions) on Wiley Online Library for rules of use; OA articles are governed by the applicable Creative Commons License.", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.95, "evidence": ["margin-band narrow/tall geometry; treated as noise"], "seed_role": "noise", "seed_confidence": 0.95, "seed_evidence": ["margin-band narrow/tall geometry; treated as noise"], "span_metadata": [{"size": 5.03000020980835, "font": "Times-Roman", "flags": 4, "color": 0, "dir": [0.0, 1.0], "wmode": 0}], "raw_observation": {"block_id": 14, "page": 18, "raw_label": "aside_text", "text": "23669608, 2024, 8, Downloaded from https://onlinelibrary.wiley.com/doi/10.1002/smkl.202301283 by Shandong University Library, Wiley Online Library on [18/02/2026]. See the Terms and Conditions (https://onlinelibrary.wiley.com/terms-and-conditions) on Wiley Online Library for rules of use; OA articles are governed by the applicable Creative Commons License.", "bbox": [1153, 22, 1171, 1533], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "23669608, 2024, 8, Downloaded from https://onlinelibrary.wiley.com/doi/10.1002/smkl.202301283 by Shandong University Library, Wiley Online Library on [18/02/2026]. See the Terms and Conditions (https://onlinelibrary.wiley.com/terms-and-conditions) on Wiley Online Library for rules of use; OA articles are governed by the applicable Creative Commons License."}, "layout_signature": {"width": 18, "width_bucket": 25, "height": 1511, "left": 1153, "top": 22, "right": 1171, "bottom": 1533, "x_center": 1162.0, "x_center_bucket": 1150, "y_center": 777.5, "x_ratio": 0.9757, "y_ratio": 0.4968, "width_ratio": 0.0151, "height_ratio": 0.9655, "line_count": 1}, "span_signature": {"font_size": 5.03, "font_size_median": 5.03, "font_size_bucket": 5.0, "font_family_norm": "Times-Roman", "bold": false, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_family_anchor", "reading_band_id": "band_136", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 19, "block_id": 0, "raw_label": "header", "raw_order": null, "bbox": [98, 44, 345, 117], "text": "ADVANCED\nSCIENCE NEWS\nwww.advancedsciencenews.com", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["header label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["header label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaSansPro-Bold", "flags": 20, "color": 255, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 0, "page": 19, "raw_label": "header", "text": "ADVANCED\nSCIENCE NEWS\nwww.advancedsciencenews.com", "bbox": [98, 44, 345, 117], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "ADVANCED\nSCIENCE NEWS\nwww.advancedsciencenews.com"}, "layout_signature": {"width": 247, "width_bucket": 250, "height": 73, "left": 98, "top": 44, "right": 345, "bottom": 117, "x_center": 221.5, "x_center_bucket": 225, "y_center": 80.5, "x_ratio": 0.186, "y_ratio": 0.0514, "width_ratio": 0.2074, "height_ratio": 0.0466, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaSansPro-Bold", "bold": true, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 19, "block_id": 1, "raw_label": "header_image", "raw_order": null, "bbox": [900, 35, 1097, 117], "text": "", "page_width": 1191, "page_height": 1565, "role": "unknown_structural", "role_confidence": 0.2, "evidence": ["unrecognized label 'header_image'"], "seed_role": "unknown_structural", "seed_confidence": 0.2, "seed_evidence": ["unrecognized label 'header_image'"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaSansPro-Bold", "flags": 20, "color": 255, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 1, "page": 19, "raw_label": "header_image", "text": "", "bbox": [900, 35, 1097, 117], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "empty", "raw_marker": null, "number": null, "kind": null, "normalized_text": ""}, "layout_signature": {"width": 197, "width_bucket": 200, "height": 82, "left": 900, "top": 35, "right": 1097, "bottom": 117, "x_center": 998.5, "x_center_bucket": 1000, "y_center": 76.0, "x_ratio": 0.8384, "y_ratio": 0.0486, "width_ratio": 0.1654, "height_ratio": 0.0524, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaSansPro-Bold", "bold": true, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": true, "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_142", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["non-structural role accepted"]}
+{"paper_id": "2HEUD5P9", "page": 19, "block_id": 2, "raw_label": "image", "raw_order": null, "bbox": [103, 150, 1085, 821], "text": "", "page_width": 1191, "page_height": 1565, "role": "figure_asset", "role_confidence": 0.85, "evidence": ["media label: image"], "seed_role": "media_asset", "seed_confidence": 0.85, "seed_evidence": ["media label: image"], "span_metadata": null, "raw_observation": {"block_id": 2, "page": 19, "raw_label": "image", "text": "", "bbox": [103, 150, 1085, 821], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "empty", "raw_marker": null, "number": null, "kind": null, "normalized_text": ""}, "layout_signature": {"width": 982, "width_bucket": 975, "height": 671, "left": 103, "top": 150, "right": 1085, "bottom": 821, "x_center": 594.0, "x_center_bucket": 600, "y_center": 485.5, "x_ratio": 0.4987, "y_ratio": 0.3102, "width_ratio": 0.8245, "height_ratio": 0.4288, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_142", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.0, "decision": "body", "evidence": []}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"], "asset_family_hint": "figure_like", "asset_family_confidence": 0.7, "asset_family_evidence": ["raw_label:image"]}
+{"paper_id": "2HEUD5P9", "page": 19, "block_id": 3, "raw_label": "figure_title", "raw_order": null, "bbox": [95, 836, 1100, 954], "text": "Figure 7. A,B) Water contact angle measurement for the Ti6Al4V substrate (A1) and Ti6Al4V substrate with BaTiO₃ coating (B1); Surface CLSM images of the Ti6Al4V substrate (A2) and Ti6Al4V substrate with BaTiO₃ coating (B2). C) Fluorescence staining of BMSCs (red, Rhodamine-phalloidin for F-actin; blue, DAPI for nucleus; green, fluorescein isothiocyanate for vinculin). Scale bar: 50 μm.[158] Copyright 2020 Elsevier. D) The osteogenic and proangiogenic functions of aged BMSCs, and activate mechanosensitive ion channel Piezo1 to promote Ca²⁺ influx.[16] Copyright 2020 Wiley-VCH. E) E-Au@H composite under NIR irradiation promoted the release of EGCG, which led to sterilization, promoted the formation of blood vessels, and accelerated the regeneration of periodontal bone tissue.[166] Copyright 2023 Elsevier.", "page_width": 1191, "page_height": 1565, "role": "figure_caption", "role_confidence": 0.92, "evidence": ["figure_title label: Figure 7. A,B) Water contact angle measurement for the Ti6Al"], "seed_role": "figure_caption", "seed_confidence": 0.92, "seed_evidence": ["figure_title label: Figure 7. A,B) Water contact angle measurement for the Ti6Al"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "STIX-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "STIX-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaSansPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaSansPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaSansPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaSansPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "STIXMath-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaSansPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaSansPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaSansPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaSansPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaSansPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaSansPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 3, "page": 19, "raw_label": "figure_title", "text": "Figure 7. A,B) Water contact angle measurement for the Ti6Al4V substrate (A1) and Ti6Al4V substrate with BaTiO₃ coating (B1); Surface CLSM images of the Ti6Al4V substrate (A2) and Ti6Al4V substrate with BaTiO₃ coating (B2). C) Fluorescence staining of BMSCs (red, Rhodamine-phalloidin for F-actin; blue, DAPI for nucleus; green, fluorescein isothiocyanate for vinculin). Scale bar: 50 μm.[158] Copyright 2020 Elsevier. D) The osteogenic and proangiogenic functions of aged BMSCs, and activate mechanosensitive ion channel Piezo1 to promote Ca²⁺ influx.[16] Copyright 2020 Wiley-VCH. E) E-Au@H composite under NIR irradiation promoted the release of EGCG, which led to sterilization, promoted the formation of blood vessels, and accelerated the regeneration of periodontal bone tissue.[166] Copyright 2023 Elsevier.", "bbox": [95, 836, 1100, 954], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "figure_number", "raw_marker": "Figure 7", "number": 7, "kind": "figure", "normalized_text": "Figure 7. A,B) Water contact angle measurement for the Ti6Al4V substrate (A1) and Ti6Al4V substrate with BaTiO₃ coating (B1); Surface CLSM images of the Ti6Al4V substrate (A2) and Ti6Al4V substrate with BaTiO₃ coating (B2). C) Fluorescence staining of BMSCs (red, Rhodamine-phalloidin for F-actin; blue, DAPI for nucleus; green, fluorescein isothiocyanate for vinculin). Scale bar: 50 μm.[158] Copyright 2020 Elsevier. D) The osteogenic and proangiogenic functions of aged BMSCs, and activate mechanosensitive ion channel Piezo1 to promote Ca²⁺ influx.[16] Copyright 2020 Wiley-VCH. E) E-Au@H composite under NIR irradiation promoted the release of EGCG, which led to sterilization, promoted the formation of blood vessels, and accelerated the regeneration of periodontal bone tissue.[166] Copyright 2023 Elsevier."}, "layout_signature": {"width": 1005, "width_bucket": 1000, "height": 118, "left": 95, "top": 836, "right": 1100, "bottom": 954, "x_center": 597.5, "x_center_bucket": 600, "y_center": 895.0, "x_ratio": 0.5017, "y_ratio": 0.5719, "width_ratio": 0.8438, "height_ratio": 0.0754, "line_count": 1}, "span_signature": {"font_size": 7.78, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Bold", "bold": true, "italic": true, "span_count": 150}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "display_zone", "style_family": "legend_like", "style_family_authority": "figure_marker", "reading_band_id": "band_139", "display_cluster_candidate_id": "disp_27_0", "layout_region": "display_zone", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.0, "decision": "body", "evidence": []}, "role_verification_status": "ACCEPT", "role_source": "accepted_figure_caption_artifact", "role_evidence": ["figure caption matched accepted figure artifact"]}
+{"paper_id": "2HEUD5P9", "page": 19, "block_id": 4, "raw_label": "text", "raw_order": 1, "bbox": [95, 981, 587, 1113], "text": "Piezo1 by fabricating a wearable pulsed triboelectric nanogenerator (WP-TENG) driven by human body movement (Figure 7D). $ ^{[16]} $ Epigallocatechin gallate (EGCG) was loaded into gold nanoparticle-modified hydrogels (EAu@H) to achieve the synergistic functions of near-infrared photosensitization, bactericidal and periodontal tissue regeneration (Figure 7E). $ ^{[166]} $", "page_width": 1191, "page_height": 1565, "role": "body_paragraph", "role_confidence": 0.6, "evidence": ["default body_paragraph for text label"], "seed_role": "body_paragraph", "seed_confidence": 0.6, "seed_evidence": ["default body_paragraph for text label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 4, "page": 19, "raw_label": "text", "text": "Piezo1 by fabricating a wearable pulsed triboelectric nanogenerator (WP-TENG) driven by human body movement (Figure 7D). $ ^{[16]} $ Epigallocatechin gallate (EGCG) was loaded into gold nanoparticle-modified hydrogels (EAu@H) to achieve the synergistic functions of near-infrared photosensitization, bactericidal and periodontal tissue regeneration (Figure 7E). $ ^{[166]} $", "bbox": [95, 981, 587, 1113], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "Piezo1 by fabricating a wearable pulsed triboelectric nanogenerator (WP-TENG) driven by human body movement (Figure 7D). $ ^{[16]} $ Epigallocatechin gallate (EGCG) was loaded into gold nanoparticle-modified hydrogels (EAu@H) to achieve the synergistic functions of near-infrared photosensitization, bactericidal and periodontal tissue regeneration (Figure 7E). $ ^{[166]} $"}, "layout_signature": {"width": 492, "width_bucket": 500, "height": 132, "left": 95, "top": 981, "right": 587, "bottom": 1113, "x_center": 341.0, "x_center_bucket": 350, "y_center": 1047.0, "x_ratio": 0.2863, "y_ratio": 0.669, "width_ratio": 0.4131, "height_ratio": 0.0843, "line_count": 1}, "span_signature": {"font_size": 8.65, "font_size_median": 8.97, "font_size_bucket": 8.5, "font_family_norm": "ScalaPro-Regular", "bold": false, "italic": true, "span_count": 57}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_140", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "zone": "body_zone", "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 19, "block_id": 5, "raw_label": "text", "raw_order": 2, "bbox": [95, 1113, 589, 1446], "text": "Physical stimuli-responsive strategies lack controllability, predictability, feasibility, and standardization in bone repair and regeneration applications according to existing research. These materials may cause damage to bone tissue, thereby affecting bone regeneration $ ^{1} $. However, physical stimuli-responsive strategies still have broad application prospects in bone repair and regeneration. For example, physical stimuli-responsive strategies can affect cell behavior by adjusting the physical properties of the extracellular matrix, thereby promoting bone repair and regeneration. In addition, physical stimuli-responsive strategies can be combined with other treatments such as drug therapy and gene therapy to improve treatment efficacy. With the development of technology, the development of physical stimuli-responsive materials will be a hot spot and new direction for the development of orthopedic biomaterials in the next decade. Multidisciplinary cross-fusion is also an inevitable trend in the clinical development of orthopedics. Therefore, future research will focus on developing better materials to promote bone tissue regeneration and functional reconstruction.", "page_width": 1191, "page_height": 1565, "role": "body_paragraph", "role_confidence": 0.6, "evidence": ["default body_paragraph for text label"], "seed_role": "body_paragraph", "seed_confidence": 0.6, "seed_evidence": ["default body_paragraph for text label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 5, "page": 19, "raw_label": "text", "text": "Physical stimuli-responsive strategies lack controllability, predictability, feasibility, and standardization in bone repair and regeneration applications according to existing research. These materials may cause damage to bone tissue, thereby affecting bone regeneration $ ^{1} $. However, physical stimuli-responsive strategies still have broad application prospects in bone repair and regeneration. For example, physical stimuli-responsive strategies can affect cell behavior by adjusting the physical properties of the extracellular matrix, thereby promoting bone repair and regeneration. In addition, physical stimuli-responsive strategies can be combined with other treatments such as drug therapy and gene therapy to improve treatment efficacy. With the development of technology, the development of physical stimuli-responsive materials will be a hot spot and new direction for the development of orthopedic biomaterials in the next decade. Multidisciplinary cross-fusion is also an inevitable trend in the clinical development of orthopedics. Therefore, future research will focus on developing better materials to promote bone tissue regeneration and functional reconstruction.", "bbox": [95, 1113, 589, 1446], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "Physical stimuli-responsive strategies lack controllability, predictability, feasibility, and standardization in bone repair and regeneration applications according to existing research. These materials may cause damage to bone tissue, thereby affecting bone regeneration $ ^{1} $. However, physical stimuli-responsive strategies still have broad application prospects in bone repair and regeneration. For example, physical stimuli-responsive strategies can affect cell behavior by adjusting the physical properties of the extracellular matrix, thereby promoting bone repair and regeneration. In addition, physical stimuli-responsive strategies can be combined with other treatments such as drug therapy and gene therapy to improve treatment efficacy. With the development of technology, the development of physical stimuli-responsive materials will be a hot spot and new direction for the development of orthopedic biomaterials in the next decade. Multidisciplinary cross-fusion is also an inevitable trend in the clinical development of orthopedics. Therefore, future research will focus on developing better materials to promote bone tissue regeneration and functional reconstruction."}, "layout_signature": {"width": 494, "width_bucket": 500, "height": 333, "left": 95, "top": 1113, "right": 589, "bottom": 1446, "x_center": 342.0, "x_center_bucket": 350, "y_center": 1279.5, "x_ratio": 0.2872, "y_ratio": 0.8176, "width_ratio": 0.4148, "height_ratio": 0.2128, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaPro-Regular", "bold": false, "italic": true, "span_count": 93}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_139", "display_cluster_candidate_id": "disp_27_0", "layout_region": "display_zone", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "zone": "body_zone", "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 19, "block_id": 6, "raw_label": "text", "raw_order": 3, "bbox": [604, 981, 1099, 1071], "text": "", "page_width": 1191, "page_height": 1565, "role": "ocr_text_missing", "role_confidence": 0.8, "evidence": ["ocr detected text region (raw_label=text) but no text extracted; no pdf backfill available"], "seed_role": "ocr_text_missing", "seed_confidence": 0.8, "seed_evidence": ["ocr detected text region (raw_label=text) but no text extracted; no pdf backfill available"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 6, "page": 19, "raw_label": "text", "text": "", "bbox": [604, 981, 1099, 1071], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "empty", "raw_marker": null, "number": null, "kind": null, "normalized_text": ""}, "layout_signature": {"width": 495, "width_bucket": 500, "height": 90, "left": 604, "top": 981, "right": 1099, "bottom": 1071, "x_center": 851.5, "x_center_bucket": 850, "y_center": 1026.0, "x_ratio": 0.7149, "y_ratio": 0.6556, "width_ratio": 0.4156, "height_ratio": 0.0575, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaPro-Regular", "bold": false, "italic": true, "span_count": 38}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": "pdf_text_layer_fallback_rejected", "_ocr_raw_status": "missing_text_rejected", "_ocr_raw_error_type": "backfill_overlaps_existing_text_block", "render_default": true, "index_default": true, "style_family": "unknown_like", "style_family_authority": "fallback", "_needs_pdf_fallback": true, "reading_band_id": "band_140", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 19, "block_id": 7, "raw_label": "paragraph_title", "raw_order": 4, "bbox": [606, 1115, 1017, 1166], "text": "4. The Underlying Mechanism of Bioactive Materials for Bone Regeneration", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["paragraph_title label with numbering: 4. The Underlying Mechanism of Bioactive Materials for Bone "], "seed_role": "section_heading", "seed_confidence": 0.85, "seed_evidence": ["paragraph_title label with numbering: 4. The Underlying Mechanism of Bioactive Materials for Bone "], "span_metadata": [{"size": 11.456999778747559, "font": "ScalaSansPro-Bold", "flags": 20, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 11.456999778747559, "font": "ScalaSansPro-Bold", "flags": 20, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 7, "page": 19, "raw_label": "paragraph_title", "text": "4. The Underlying Mechanism of Bioactive Materials for Bone Regeneration", "bbox": [606, 1115, 1017, 1166], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_dot", "raw_marker": "4.", "number": 4, "kind": "reference", "normalized_text": "4. The Underlying Mechanism of Bioactive Materials for Bone Regeneration"}, "layout_signature": {"width": 411, "width_bucket": 400, "height": 51, "left": 606, "top": 1115, "right": 1017, "bottom": 1166, "x_center": 811.5, "x_center_bucket": 800, "y_center": 1140.5, "x_ratio": 0.6814, "y_ratio": 0.7288, "width_ratio": 0.3451, "height_ratio": 0.0326, "line_count": 1}, "span_signature": {"font_size": 11.46, "font_size_median": 11.46, "font_size_bucket": 11.5, "font_family_norm": "ScalaSansPro-Bold", "bold": true, "italic": true, "span_count": 2}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_139", "display_cluster_candidate_id": "disp_27_0", "layout_region": "display_zone", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 19, "block_id": 8, "raw_label": "text", "raw_order": 5, "bbox": [605, 1179, 1099, 1446], "text": "Understanding the molecular mechanism of bioactive materials on bone tissue can improve the design and preparation of materials to better promote bone regeneration. By studying the molecular mechanism, we can discover the interaction between the material and cells and tissues, so as to optimize the biological activity of the material and improve the effect of bone regeneration. Different bioactive materials may have different molecular mechanisms for bone regeneration. Through in-depth study of molecular mechanisms, we can understand the characteristics and application range of different materials, so as to guide the appropriate material selection and application. This helps to improve the success rate and treatment effect of bone tissue engineering.", "page_width": 1191, "page_height": 1565, "role": "body_paragraph", "role_confidence": 0.6, "evidence": ["default body_paragraph for text label"], "seed_role": "body_paragraph", "seed_confidence": 0.6, "seed_evidence": ["default body_paragraph for text label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 8, "page": 19, "raw_label": "text", "text": "Understanding the molecular mechanism of bioactive materials on bone tissue can improve the design and preparation of materials to better promote bone regeneration. By studying the molecular mechanism, we can discover the interaction between the material and cells and tissues, so as to optimize the biological activity of the material and improve the effect of bone regeneration. Different bioactive materials may have different molecular mechanisms for bone regeneration. Through in-depth study of molecular mechanisms, we can understand the characteristics and application range of different materials, so as to guide the appropriate material selection and application. This helps to improve the success rate and treatment effect of bone tissue engineering.", "bbox": [605, 1179, 1099, 1446], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "Understanding the molecular mechanism of bioactive materials on bone tissue can improve the design and preparation of materials to better promote bone regeneration. By studying the molecular mechanism, we can discover the interaction between the material and cells and tissues, so as to optimize the biological activity of the material and improve the effect of bone regeneration. Different bioactive materials may have different molecular mechanisms for bone regeneration. Through in-depth study of molecular mechanisms, we can understand the characteristics and application range of different materials, so as to guide the appropriate material selection and application. This helps to improve the success rate and treatment effect of bone tissue engineering."}, "layout_signature": {"width": 494, "width_bucket": 500, "height": 267, "left": 605, "top": 1179, "right": 1099, "bottom": 1446, "x_center": 852.0, "x_center_bucket": 850, "y_center": 1312.5, "x_ratio": 0.7154, "y_ratio": 0.8387, "width_ratio": 0.4148, "height_ratio": 0.1706, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaPro-Regular", "bold": false, "italic": true, "span_count": 32}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_140", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "zone": "tail_nonref_hold_zone", "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 19, "block_id": 9, "raw_label": "footer", "raw_order": null, "bbox": [99, 1487, 289, 1505], "text": "Small Methods 2024, 8, 2301283", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["footer label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["footer label"], "span_metadata": [{"size": 6.973800182342529, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 9, "page": 19, "raw_label": "footer", "text": "Small Methods 2024, 8, 2301283", "bbox": [99, 1487, 289, 1505], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "Small Methods 2024, 8, 2301283"}, "layout_signature": {"width": 190, "width_bucket": 200, "height": 18, "left": 99, "top": 1487, "right": 289, "bottom": 1505, "x_center": 194.0, "x_center_bucket": 200, "y_center": 1496.0, "x_ratio": 0.1629, "y_ratio": 0.9559, "width_ratio": 0.1595, "height_ratio": 0.0115, "line_count": 1}, "span_signature": {"font_size": 6.97, "font_size_median": 6.97, "font_size_bucket": 7.0, "font_family_norm": "ScalaSansPro-Italic", "bold": true, "italic": true, "span_count": 5}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_138", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 19, "block_id": 10, "raw_label": "number", "raw_order": null, "bbox": [526, 1484, 669, 1508], "text": "2301283 (19 of 27)", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.9, "evidence": ["page number label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["page number label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaSansPro-Bold", "flags": 20, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 10, "page": 19, "raw_label": "number", "text": "2301283 (19 of 27)", "bbox": [526, 1484, 669, 1508], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_dot", "raw_marker": "2301283", "number": 2301283, "kind": "reference", "normalized_text": "2301283 (19 of 27)"}, "layout_signature": {"width": 143, "width_bucket": 150, "height": 24, "left": 526, "top": 1484, "right": 669, "bottom": 1508, "x_center": 597.5, "x_center_bucket": 600, "y_center": 1496.0, "x_ratio": 0.5017, "y_ratio": 0.9559, "width_ratio": 0.1201, "height_ratio": 0.0153, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaSansPro-Bold", "bold": true, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_family_anchor", "reading_band_id": "band_141", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "hard", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 19, "block_id": 11, "raw_label": "footer", "raw_order": null, "bbox": [937, 1486, 1096, 1506], "text": "© 2024 Wiley-VCH GmbH", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["footer label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["footer label"], "span_metadata": [{"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 11, "page": 19, "raw_label": "footer", "text": "© 2024 Wiley-VCH GmbH", "bbox": [937, 1486, 1096, 1506], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "© 2024 Wiley-VCH GmbH"}, "layout_signature": {"width": 159, "width_bucket": 150, "height": 20, "left": 937, "top": 1486, "right": 1096, "bottom": 1506, "x_center": 1016.5, "x_center_bucket": 1025, "y_center": 1496.0, "x_ratio": 0.8535, "y_ratio": 0.9559, "width_ratio": 0.1335, "height_ratio": 0.0128, "line_count": 1}, "span_signature": {"font_size": 6.97, "font_size_median": 6.97, "font_size_bucket": 7.0, "font_family_norm": "ScalaSansPro-Regular", "bold": false, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_142", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 19, "block_id": 12, "raw_label": "aside_text", "raw_order": null, "bbox": [1154, 31, 1171, 1535], "text": "23699608, 2024, 8, Downloaded from https://onlinelibrary.wiley.com/doi/10.1002/smkt.202301283 by Shandong University Library, Wiley Online Library on [18/02/2026]. See the Terms and Conditions (https://onlinelibrary.wiley.com/terms-and-conditions) on Wiley Online Library for rules of use; OA articles are governed by the applicable Creative Commons License", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.95, "evidence": ["margin-band narrow/tall geometry; treated as noise"], "seed_role": "noise", "seed_confidence": 0.95, "seed_evidence": ["margin-band narrow/tall geometry; treated as noise"], "span_metadata": [{"size": 5.03000020980835, "font": "Times-Roman", "flags": 4, "color": 0, "dir": [0.0, 1.0], "wmode": 0}], "raw_observation": {"block_id": 12, "page": 19, "raw_label": "aside_text", "text": "23699608, 2024, 8, Downloaded from https://onlinelibrary.wiley.com/doi/10.1002/smkt.202301283 by Shandong University Library, Wiley Online Library on [18/02/2026]. See the Terms and Conditions (https://onlinelibrary.wiley.com/terms-and-conditions) on Wiley Online Library for rules of use; OA articles are governed by the applicable Creative Commons License", "bbox": [1154, 31, 1171, 1535], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "23699608, 2024, 8, Downloaded from https://onlinelibrary.wiley.com/doi/10.1002/smkt.202301283 by Shandong University Library, Wiley Online Library on [18/02/2026]. See the Terms and Conditions (https://onlinelibrary.wiley.com/terms-and-conditions) on Wiley Online Library for rules of use; OA articles are governed by the applicable Creative Commons License"}, "layout_signature": {"width": 17, "width_bucket": 25, "height": 1504, "left": 1154, "top": 31, "right": 1171, "bottom": 1535, "x_center": 1162.5, "x_center_bucket": 1150, "y_center": 783.0, "x_ratio": 0.9761, "y_ratio": 0.5003, "width_ratio": 0.0143, "height_ratio": 0.961, "line_count": 1}, "span_signature": {"font_size": 5.03, "font_size_median": 5.03, "font_size_bucket": 5.0, "font_family_norm": "Times-Roman", "bold": false, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_family_anchor", "reading_band_id": "band_142", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 20, "block_id": 0, "raw_label": "header", "raw_order": null, "bbox": [93, 45, 339, 116], "text": "ADVANCED\nSCIENCE NEWS\nwww.advancedsciencenews.com", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["header label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["header label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaSansPro-Bold", "flags": 20, "color": 255, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 0, "page": 20, "raw_label": "header", "text": "ADVANCED\nSCIENCE NEWS\nwww.advancedsciencenews.com", "bbox": [93, 45, 339, 116], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "ADVANCED\nSCIENCE NEWS\nwww.advancedsciencenews.com"}, "layout_signature": {"width": 246, "width_bucket": 250, "height": 71, "left": 93, "top": 45, "right": 339, "bottom": 116, "x_center": 216.0, "x_center_bucket": 225, "y_center": 80.5, "x_ratio": 0.1814, "y_ratio": 0.0514, "width_ratio": 0.2065, "height_ratio": 0.0454, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaSansPro-Bold", "bold": true, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 20, "block_id": 1, "raw_label": "header", "raw_order": null, "bbox": [997, 36, 1089, 96], "text": "small methods", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["header label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["header label"], "span_metadata": null, "raw_observation": {"block_id": 1, "page": 20, "raw_label": "header", "text": "small methods", "bbox": [997, 36, 1089, 96], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "short_fragment", "raw_marker": "small methods", "number": null, "kind": "short_fragment", "normalized_text": "small methods"}, "layout_signature": {"width": 92, "width_bucket": 100, "height": 60, "left": 997, "top": 36, "right": 1089, "bottom": 96, "x_center": 1043.0, "x_center_bucket": 1050, "y_center": 66.0, "x_ratio": 0.8757, "y_ratio": 0.0422, "width_ratio": 0.0772, "height_ratio": 0.0383, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": true, "_container_bbox": [1000.0802235557833, 37.836628863963085, 1078.3616835103696, 91.04600210547972], "_container_text": "small methods", "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_142", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.6, "decision": "structured_insert_candidate", "evidence": ["visual_container", "narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 20, "block_id": 2, "raw_label": "header", "raw_order": null, "bbox": [897, 97, 1090, 116], "text": "www.small-methods.com", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["header label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["header label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaSansPro-Bold", "flags": 20, "color": 255, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 2, "page": 20, "raw_label": "header", "text": "www.small-methods.com", "bbox": [897, 97, 1090, 116], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "www.small-methods.com"}, "layout_signature": {"width": 193, "width_bucket": 200, "height": 19, "left": 897, "top": 97, "right": 1090, "bottom": 116, "x_center": 993.5, "x_center_bucket": 1000, "y_center": 106.5, "x_ratio": 0.8342, "y_ratio": 0.0681, "width_ratio": 0.162, "height_ratio": 0.0121, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaSansPro-Bold", "bold": true, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_142", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 20, "block_id": 3, "raw_label": "paragraph_title", "raw_order": 1, "bbox": [91, 149, 432, 171], "text": "4.1. Regulation of Stem Cells by Biomaterials", "page_width": 1191, "page_height": 1565, "role": "subsection_heading", "role_confidence": 0.85, "evidence": ["paragraph_title label with numbering: 4.1. Regulation of Stem Cells by Biomaterials"], "seed_role": "subsection_heading", "seed_confidence": 0.85, "seed_evidence": ["paragraph_title label with numbering: 4.1. Regulation of Stem Cells by Biomaterials"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaSansPro-Bold", "flags": 20, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 3, "page": 20, "raw_label": "paragraph_title", "text": "4.1. Regulation of Stem Cells by Biomaterials", "bbox": [91, 149, 432, 171], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "heading_numbered", "raw_marker": "4.1", "number": "4.1", "kind": "heading", "normalized_text": "4.1. Regulation of Stem Cells by Biomaterials"}, "layout_signature": {"width": 341, "width_bucket": 350, "height": 22, "left": 91, "top": 149, "right": 432, "bottom": 171, "x_center": 261.5, "x_center_bucket": 250, "y_center": 160.0, "x_ratio": 0.2196, "y_ratio": 0.1022, "width_ratio": 0.2863, "height_ratio": 0.0141, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaSansPro-Bold", "bold": true, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_139", "display_cluster_candidate_id": "disp_27_0", "layout_region": "display_zone", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "zone": "body_zone", "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "accepted_heading", "role_evidence": ["heading verified by heading artifact"]}
+{"paper_id": "2HEUD5P9", "page": 20, "block_id": 4, "raw_label": "text", "raw_order": 2, "bbox": [90, 192, 582, 565], "text": "Stem cells are undifferentiated cells that self-renew and produce an abundance of undifferentiated offspring. They have strong proliferative capacity and multi-lineage differentiation ability; therefore, they play an important role in tissue regeneration. Embryonic stem cells (ESCs) have self-renewal ability and pluripotency and can differentiate into various cell types, including the capacity to form osteogenic cells. $ ^{[167,168]} $ Induced pluripotent stem cells (iPSCs) possess limitless proliferation and pluripotent differentiation potential with no ethical issues and are thus regarded as a promising option for osteogenesis and bone repair. iPSCs are capable of differentiating into osteoblasts. $ ^{[169]} $ MSCs with outstanding proliferation and differentiation potential are multipotent stromal cells that can differentiate into several cell types, including osteoblasts, chondrocytes, adipocytes, myocytes, and endothelial cells. MSCs have immunomodulatory functions and retain the features of stem cells after multiple passages without immune rejection.", "page_width": 1191, "page_height": 1565, "role": "body_paragraph", "role_confidence": 0.6, "evidence": ["default body_paragraph for text label"], "seed_role": "body_paragraph", "seed_confidence": 0.6, "seed_evidence": ["default body_paragraph for text label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 4, "page": 20, "raw_label": "text", "text": "Stem cells are undifferentiated cells that self-renew and produce an abundance of undifferentiated offspring. They have strong proliferative capacity and multi-lineage differentiation ability; therefore, they play an important role in tissue regeneration. Embryonic stem cells (ESCs) have self-renewal ability and pluripotency and can differentiate into various cell types, including the capacity to form osteogenic cells. $ ^{[167,168]} $ Induced pluripotent stem cells (iPSCs) possess limitless proliferation and pluripotent differentiation potential with no ethical issues and are thus regarded as a promising option for osteogenesis and bone repair. iPSCs are capable of differentiating into osteoblasts. $ ^{[169]} $ MSCs with outstanding proliferation and differentiation potential are multipotent stromal cells that can differentiate into several cell types, including osteoblasts, chondrocytes, adipocytes, myocytes, and endothelial cells. MSCs have immunomodulatory functions and retain the features of stem cells after multiple passages without immune rejection.", "bbox": [90, 192, 582, 565], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "Stem cells are undifferentiated cells that self-renew and produce an abundance of undifferentiated offspring. They have strong proliferative capacity and multi-lineage differentiation ability; therefore, they play an important role in tissue regeneration. Embryonic stem cells (ESCs) have self-renewal ability and pluripotency and can differentiate into various cell types, including the capacity to form osteogenic cells. $ ^{[167,168]} $ Induced pluripotent stem cells (iPSCs) possess limitless proliferation and pluripotent differentiation potential with no ethical issues and are thus regarded as a promising option for osteogenesis and bone repair. iPSCs are capable of differentiating into osteoblasts. $ ^{[169]} $ MSCs with outstanding proliferation and differentiation potential are multipotent stromal cells that can differentiate into several cell types, including osteoblasts, chondrocytes, adipocytes, myocytes, and endothelial cells. MSCs have immunomodulatory functions and retain the features of stem cells after multiple passages without immune rejection."}, "layout_signature": {"width": 492, "width_bucket": 500, "height": 373, "left": 90, "top": 192, "right": 582, "bottom": 565, "x_center": 336.0, "x_center_bucket": 325, "y_center": 378.5, "x_ratio": 0.2821, "y_ratio": 0.2419, "width_ratio": 0.4131, "height_ratio": 0.2383, "line_count": 1}, "span_signature": {"font_size": 8.79, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaPro-Regular", "bold": false, "italic": true, "span_count": 99}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_140", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "zone": "body_zone", "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 20, "block_id": 5, "raw_label": "text", "raw_order": 3, "bbox": [90, 566, 582, 1073], "text": "Bone biomaterials act as platforms to facilitate stem cell adhesion and growth during bone repair. The chemical components, surface characteristics, and topographic structure of bone biomaterials directly affect stem cell adhesion, proliferation, differentiation, and angiogenesis. Various attempts have been made to combine scaffolds and stem cells for bone regeneration. Human ESC-derived MSCs encapsulated in alginate microbeads in macroporous CaP cement exhibit good cytocompatibility, osteogenesis, and mineralization. $ ^{[170]} $ ECM-coated PLGA scaffolds enhanced the proliferation of ESCs, calcium deposition, and osteocalcin expression. $ ^{[171]} $ Poly(L-lactic acid) (PLLA) loaded with calcium-deficient nanohydroxyapatite (d-HAP) promotes the expression of osteogenic markers in iPSCs compared to pure PLLA. $ ^{[172]} $ Gingival MSC-laden alginate-based hydrogels with controllable mechanical properties exhibited good biocompatibility, biodegradability, and osteoconductivity after subcutaneous implantation in mice and facilitated craniofacial bone regeneration. $ ^{[173]} $ A composite of bone marrow-derived stromal cells and $ \\beta $-TCP transplanted into a monkey femoral defect exhibited enhanced bone regeneration compared to $ \\beta $-TCP alone. $ ^{[174]} $ A chitosan scaffold combined with osteogenically induced bone marrow MSCs promoted the formation of new bone and collagen in the pores of the scaffold and showed excellent biodegradability. $ ^{[175]} $", "page_width": 1191, "page_height": 1565, "role": "body_paragraph", "role_confidence": 0.6, "evidence": ["default body_paragraph for text label"], "seed_role": "body_paragraph", "seed_confidence": 0.6, "seed_evidence": ["default body_paragraph for text label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "STIXMath-Italic", "flags": 6, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "STIXMath-Italic", "flags": 6, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "STIXMath-Italic", "flags": 6, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "STIXMath-Italic", "flags": 6, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 5, "page": 20, "raw_label": "text", "text": "Bone biomaterials act as platforms to facilitate stem cell adhesion and growth during bone repair. The chemical components, surface characteristics, and topographic structure of bone biomaterials directly affect stem cell adhesion, proliferation, differentiation, and angiogenesis. Various attempts have been made to combine scaffolds and stem cells for bone regeneration. Human ESC-derived MSCs encapsulated in alginate microbeads in macroporous CaP cement exhibit good cytocompatibility, osteogenesis, and mineralization. $ ^{[170]} $ ECM-coated PLGA scaffolds enhanced the proliferation of ESCs, calcium deposition, and osteocalcin expression. $ ^{[171]} $ Poly(L-lactic acid) (PLLA) loaded with calcium-deficient nanohydroxyapatite (d-HAP) promotes the expression of osteogenic markers in iPSCs compared to pure PLLA. $ ^{[172]} $ Gingival MSC-laden alginate-based hydrogels with controllable mechanical properties exhibited good biocompatibility, biodegradability, and osteoconductivity after subcutaneous implantation in mice and facilitated craniofacial bone regeneration. $ ^{[173]} $ A composite of bone marrow-derived stromal cells and $ \\beta $-TCP transplanted into a monkey femoral defect exhibited enhanced bone regeneration compared to $ \\beta $-TCP alone. $ ^{[174]} $ A chitosan scaffold combined with osteogenically induced bone marrow MSCs promoted the formation of new bone and collagen in the pores of the scaffold and showed excellent biodegradability. $ ^{[175]} $", "bbox": [90, 566, 582, 1073], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "Bone biomaterials act as platforms to facilitate stem cell adhesion and growth during bone repair. The chemical components, surface characteristics, and topographic structure of bone biomaterials directly affect stem cell adhesion, proliferation, differentiation, and angiogenesis. Various attempts have been made to combine scaffolds and stem cells for bone regeneration. Human ESC-derived MSCs encapsulated in alginate microbeads in macroporous CaP cement exhibit good cytocompatibility, osteogenesis, and mineralization. $ ^{[170]} $ ECM-coated PLGA scaffolds enhanced the proliferation of ESCs, calcium deposition, and osteocalcin expression. $ ^{[171]} $ Poly(L-lactic acid) (PLLA) loaded with calcium-deficient nanohydroxyapatite (d-HAP) promotes the expression of osteogenic markers in iPSCs compared to pure PLLA. $ ^{[172]} $ Gingival MSC-laden alginate-based hydrogels with controllable mechanical properties exhibited good biocompatibility, biodegradability, and osteoconductivity after subcutaneous implantation in mice and facilitated craniofacial bone regeneration. $ ^{[173]} $ A composite of bone marrow-derived stromal cells and $ \\beta $-TCP transplanted into a monkey femoral defect exhibited enhanced bone regeneration compared to $ \\beta $-TCP alone. $ ^{[174]} $ A chitosan scaffold combined with osteogenically induced bone marrow MSCs promoted the formation of new bone and collagen in the pores of the scaffold and showed excellent biodegradability. $ ^{[175]} $"}, "layout_signature": {"width": 492, "width_bucket": 500, "height": 507, "left": 90, "top": 566, "right": 582, "bottom": 1073, "x_center": 336.0, "x_center_bucket": 325, "y_center": 819.5, "x_ratio": 0.2821, "y_ratio": 0.5236, "width_ratio": 0.4131, "height_ratio": 0.324, "line_count": 1}, "span_signature": {"font_size": 8.71, "font_size_median": 8.97, "font_size_bucket": 8.5, "font_family_norm": "ScalaPro-Regular", "bold": false, "italic": true, "span_count": 209}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_139", "display_cluster_candidate_id": "disp_27_0", "layout_region": "display_zone", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "zone": "body_zone", "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 20, "block_id": 6, "raw_label": "paragraph_title", "raw_order": 4, "bbox": [91, 1102, 506, 1148], "text": "4.2. Biomaterial-Induced Pathway Modulation for Bone Regeneration", "page_width": 1191, "page_height": 1565, "role": "subsection_heading", "role_confidence": 0.85, "evidence": ["paragraph_title label with numbering: 4.2. Biomaterial-Induced Pathway Modulation for Bone Regener"], "seed_role": "subsection_heading", "seed_confidence": 0.85, "seed_evidence": ["paragraph_title label with numbering: 4.2. Biomaterial-Induced Pathway Modulation for Bone Regener"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaSansPro-Bold", "flags": 20, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaSansPro-Bold", "flags": 20, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 6, "page": 20, "raw_label": "paragraph_title", "text": "4.2. Biomaterial-Induced Pathway Modulation for Bone Regeneration", "bbox": [91, 1102, 506, 1148], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "heading_numbered", "raw_marker": "4.2", "number": "4.2", "kind": "heading", "normalized_text": "4.2. Biomaterial-Induced Pathway Modulation for Bone Regeneration"}, "layout_signature": {"width": 415, "width_bucket": 425, "height": 46, "left": 91, "top": 1102, "right": 506, "bottom": 1148, "x_center": 298.5, "x_center_bucket": 300, "y_center": 1125.0, "x_ratio": 0.2506, "y_ratio": 0.7188, "width_ratio": 0.3484, "height_ratio": 0.0294, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaSansPro-Bold", "bold": true, "italic": true, "span_count": 2}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_140", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "zone": "body_zone", "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "accepted_heading", "role_evidence": ["heading verified by heading artifact"]}
+{"paper_id": "2HEUD5P9", "page": 20, "block_id": 7, "raw_label": "text", "raw_order": 5, "bbox": [90, 1168, 581, 1302], "text": "Several signaling pathways and transcription factors have been shown to regulate the osteogenic differentiation of stem cells. To develop novel strategies for bone repair and regeneration, it is necessary to fully understand the underlying molecular mechanisms associated with the interactions between bone biomaterials and stem cells.", "page_width": 1191, "page_height": 1565, "role": "body_paragraph", "role_confidence": 0.6, "evidence": ["default body_paragraph for text label"], "seed_role": "body_paragraph", "seed_confidence": 0.6, "seed_evidence": ["default body_paragraph for text label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 7, "page": 20, "raw_label": "text", "text": "Several signaling pathways and transcription factors have been shown to regulate the osteogenic differentiation of stem cells. To develop novel strategies for bone repair and regeneration, it is necessary to fully understand the underlying molecular mechanisms associated with the interactions between bone biomaterials and stem cells.", "bbox": [90, 1168, 581, 1302], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "Several signaling pathways and transcription factors have been shown to regulate the osteogenic differentiation of stem cells. To develop novel strategies for bone repair and regeneration, it is necessary to fully understand the underlying molecular mechanisms associated with the interactions between bone biomaterials and stem cells."}, "layout_signature": {"width": 491, "width_bucket": 500, "height": 134, "left": 90, "top": 1168, "right": 581, "bottom": 1302, "x_center": 335.5, "x_center_bucket": 325, "y_center": 1235.0, "x_ratio": 0.2817, "y_ratio": 0.7891, "width_ratio": 0.4123, "height_ratio": 0.0856, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaPro-Regular", "bold": false, "italic": true, "span_count": 52}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_139", "display_cluster_candidate_id": "disp_27_0", "layout_region": "display_zone", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "zone": "body_zone", "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 20, "block_id": 8, "raw_label": "paragraph_title", "raw_order": 6, "bbox": [92, 1334, 317, 1357], "text": "4.2.1. BMP Signaling Pathway", "page_width": 1191, "page_height": 1565, "role": "sub_subsection_heading", "role_confidence": 0.85, "evidence": ["paragraph_title label with numbering: 4.2.1. BMP Signaling Pathway"], "seed_role": "sub_subsection_heading", "seed_confidence": 0.85, "seed_evidence": ["paragraph_title label with numbering: 4.2.1. BMP Signaling Pathway"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaSansPro-Italic", "flags": 6, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 8, "page": 20, "raw_label": "paragraph_title", "text": "4.2.1. BMP Signaling Pathway", "bbox": [92, 1334, 317, 1357], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "heading_numbered", "raw_marker": "4.2.1", "number": "4.2.1", "kind": "heading", "normalized_text": "4.2.1. BMP Signaling Pathway"}, "layout_signature": {"width": 225, "width_bucket": 225, "height": 23, "left": 92, "top": 1334, "right": 317, "bottom": 1357, "x_center": 204.5, "x_center_bucket": 200, "y_center": 1345.5, "x_ratio": 0.1717, "y_ratio": 0.8597, "width_ratio": 0.1889, "height_ratio": 0.0147, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaSansPro-Italic", "bold": false, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_140", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "zone": "body_zone", "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 20, "block_id": 9, "raw_label": "text", "raw_order": 7, "bbox": [90, 1376, 582, 1445], "text": "BMPs belong to the TGF- $ \\beta $ superfamily and are of great importance in bone formation and tissue homeostasis. This signaling is initiated by the binding of BMP to BMP receptors on the cell membrane, and the downstream Smad proteins are then phosphorylated by activated receptors. Smad complexes translocate into the nucleus, activating osteogenesis-related transcription factors and their corresponding downstream targets. BMPs regulate stem cell growth and differentiation and accelerate stem cell osteogenic differentiation. BMP-2, 4, 6, 7, and 9 effectively improve osteogenic differentiation in MSCs and induce new bone formation. Several biomaterials have been shown to activate the BMP signaling pathway. Nanofibrous HAP/chitosan nanocomposite scaffolds significantly promoted the proliferation and adhesion of MSCs, and the composite upregulated the expression of Smad1, BMP-2/4, Runx2, ALP, collagen I, integrin subunits, and myosins. Furthermore, the key proteins in the BMP signaling pathway, pSmad1/5/8, exhibited clear nuclear localization, and osteocalcin was significantly increased on the scaffold. Nanofibrous HAP/chitosan scaffolds combined with MSCs improved bone regeneration in cranial bone defects by initiating the integrin-BMP/Smad pathway. $ ^{[6]} $ Nanostructured titanium discs treated with $ H_{2}SO_{4}/H_{2}O_{2} $ promote osteoblast differentiation in osteoblastic cells by increasing the endogenous secretion of BMP-2 and regulating the BMP pathway. $ ^{[176]} $ BMP2-modified black phosphorus (BP@BMP2) nanosheets to PLLA electrospun fibrous scaffold, with a combination of recruiting osteoblast precursor cells and biomineralization properties for bone regeneration (Figure 8A,B). $ ^{[177]} $", "page_width": 1191, "page_height": 1565, "role": "body_paragraph", "role_confidence": 0.6, "evidence": ["default body_paragraph for text label"], "seed_role": "body_paragraph", "seed_confidence": 0.6, "seed_evidence": ["default body_paragraph for text label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "STIXMath-Italic", "flags": 6, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 9, "page": 20, "raw_label": "text", "text": "BMPs belong to the TGF- $ \\beta $ superfamily and are of great importance in bone formation and tissue homeostasis. This signaling is initiated by the binding of BMP to BMP receptors on the cell membrane, and the downstream Smad proteins are then phosphorylated by activated receptors. Smad complexes translocate into the nucleus, activating osteogenesis-related transcription factors and their corresponding downstream targets. BMPs regulate stem cell growth and differentiation and accelerate stem cell osteogenic differentiation. BMP-2, 4, 6, 7, and 9 effectively improve osteogenic differentiation in MSCs and induce new bone formation. Several biomaterials have been shown to activate the BMP signaling pathway. Nanofibrous HAP/chitosan nanocomposite scaffolds significantly promoted the proliferation and adhesion of MSCs, and the composite upregulated the expression of Smad1, BMP-2/4, Runx2, ALP, collagen I, integrin subunits, and myosins. Furthermore, the key proteins in the BMP signaling pathway, pSmad1/5/8, exhibited clear nuclear localization, and osteocalcin was significantly increased on the scaffold. Nanofibrous HAP/chitosan scaffolds combined with MSCs improved bone regeneration in cranial bone defects by initiating the integrin-BMP/Smad pathway. $ ^{[6]} $ Nanostructured titanium discs treated with $ H_{2}SO_{4}/H_{2}O_{2} $ promote osteoblast differentiation in osteoblastic cells by increasing the endogenous secretion of BMP-2 and regulating the BMP pathway. $ ^{[176]} $ BMP2-modified black phosphorus (BP@BMP2) nanosheets to PLLA electrospun fibrous scaffold, with a combination of recruiting osteoblast precursor cells and biomineralization properties for bone regeneration (Figure 8A,B). $ ^{[177]} $", "bbox": [90, 1376, 582, 1445], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "BMPs belong to the TGF- $ \\beta $ superfamily and are of great importance in bone formation and tissue homeostasis. This signaling is initiated by the binding of BMP to BMP receptors on the cell membrane, and the downstream Smad proteins are then phosphorylated by activated receptors. Smad complexes translocate into the nucleus, activating osteogenesis-related transcription factors and their corresponding downstream targets. BMPs regulate stem cell growth and differentiation and accelerate stem cell osteogenic differentiation. BMP-2, 4, 6, 7, and 9 effectively improve osteogenic differentiation in MSCs and induce new bone formation. Several biomaterials have been shown to activate the BMP signaling pathway. Nanofibrous HAP/chitosan nanocomposite scaffolds significantly promoted the proliferation and adhesion of MSCs, and the composite upregulated the expression of Smad1, BMP-2/4, Runx2, ALP, collagen I, integrin subunits, and myosins. Furthermore, the key proteins in the BMP signaling pathway, pSmad1/5/8, exhibited clear nuclear localization, and osteocalcin was significantly increased on the scaffold. Nanofibrous HAP/chitosan scaffolds combined with MSCs improved bone regeneration in cranial bone defects by initiating the integrin-BMP/Smad pathway. $ ^{[6]} $ Nanostructured titanium discs treated with $ H_{2}SO_{4}/H_{2}O_{2} $ promote osteoblast differentiation in osteoblastic cells by increasing the endogenous secretion of BMP-2 and regulating the BMP pathway. $ ^{[176]} $ BMP2-modified black phosphorus (BP@BMP2) nanosheets to PLLA electrospun fibrous scaffold, with a combination of recruiting osteoblast precursor cells and biomineralization properties for bone regeneration (Figure 8A,B). $ ^{[177]} $"}, "layout_signature": {"width": 492, "width_bucket": 500, "height": 69, "left": 90, "top": 1376, "right": 582, "bottom": 1445, "x_center": 336.0, "x_center_bucket": 325, "y_center": 1410.5, "x_ratio": 0.2821, "y_ratio": 0.9013, "width_ratio": 0.4131, "height_ratio": 0.0441, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaPro-Regular", "bold": false, "italic": true, "span_count": 61}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_138", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "zone": "body_zone", "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 20, "block_id": 10, "raw_label": "text", "raw_order": 8, "bbox": [600, 150, 1093, 700], "text": "", "page_width": 1191, "page_height": 1565, "role": "ocr_text_missing", "role_confidence": 0.8, "evidence": ["ocr detected text region (raw_label=text) but no text extracted; no pdf backfill available"], "seed_role": "ocr_text_missing", "seed_confidence": 0.8, "seed_evidence": ["ocr detected text region (raw_label=text) but no text extracted; no pdf backfill available"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Bold", "flags": 20, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Bold", "flags": 20, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 10, "page": 20, "raw_label": "text", "text": "", "bbox": [600, 150, 1093, 700], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "empty", "raw_marker": null, "number": null, "kind": null, "normalized_text": ""}, "layout_signature": {"width": 493, "width_bucket": 500, "height": 550, "left": 600, "top": 150, "right": 1093, "bottom": 700, "x_center": 846.5, "x_center_bucket": 850, "y_center": 425.0, "x_ratio": 0.7107, "y_ratio": 0.2716, "width_ratio": 0.4139, "height_ratio": 0.3514, "line_count": 1}, "span_signature": {"font_size": 8.77, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaPro-Regular", "bold": true, "italic": true, "span_count": 199}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": "pdf_text_layer_fallback_rejected", "_ocr_raw_status": "missing_text_rejected", "_ocr_raw_error_type": "backfill_overlaps_existing_text_block", "render_default": true, "index_default": true, "style_family": "unknown_like", "style_family_authority": "fallback", "_needs_pdf_fallback": true, "reading_band_id": "band_141", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "hard", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 20, "block_id": 11, "raw_label": "paragraph_title", "raw_order": 9, "bbox": [603, 720, 821, 743], "text": "4.2.2. Wnt Signaling Pathway", "page_width": 1191, "page_height": 1565, "role": "sub_subsection_heading", "role_confidence": 0.85, "evidence": ["paragraph_title label with numbering: 4.2.2. Wnt Signaling Pathway"], "seed_role": "sub_subsection_heading", "seed_confidence": 0.85, "seed_evidence": ["paragraph_title label with numbering: 4.2.2. Wnt Signaling Pathway"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaSansPro-Italic", "flags": 6, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 11, "page": 20, "raw_label": "paragraph_title", "text": "4.2.2. Wnt Signaling Pathway", "bbox": [603, 720, 821, 743], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "heading_numbered", "raw_marker": "4.2.2", "number": "4.2.2", "kind": "heading", "normalized_text": "4.2.2. Wnt Signaling Pathway"}, "layout_signature": {"width": 218, "width_bucket": 225, "height": 23, "left": 603, "top": 720, "right": 821, "bottom": 743, "x_center": 712.0, "x_center_bucket": 700, "y_center": 731.5, "x_ratio": 0.5978, "y_ratio": 0.4674, "width_ratio": 0.183, "height_ratio": 0.0147, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaSansPro-Italic", "bold": false, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_142", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "zone": "body_zone", "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 20, "block_id": 12, "raw_label": "text", "raw_order": 10, "bbox": [600, 762, 1093, 1336], "text": "The Wnt/ $ \\beta $-catenin signaling pathway is recognized as a crucial signal for the regulation of stem cell osteogenic differentiation and is strongly associated with the formation and regeneration of bone. The binding of canonical Wnt proteins to the Frizzled/LRP receptor leads to the activation of $ \\beta $-catenin, ultimately regulating the expression of osteogenic transcription factors. The combination of non-canonical Wnt proteins with the Frizzled receptor activates heterotrimeric G protein and regulates intracellular Ca $ ^{2+} $ signaling through $ \\beta $-catenin independent pathways. The osteogenic functions of some materials are closely related to this signaling pathway. It has been shown that a PCL nanofiber scaffold promotes human MSCs adhesion and proliferation and significantly increases the osteogenic differentiation potency of MSCs by consistently activating the Wnt/ $ \\beta $-catenin and Smad3 pathways. $ ^{[178]} $ Silk braids with mechanical stiffness comparable to that of trabecular bone promoted human preosteoblast differentiation within their 3D microenvironment by the activation of Wnt/ $ \\beta $-catenin signaling. $ ^{[179]} $ The Wnt/ $ \\beta $-catenin pathway suppresses the adipogenic differentiation potential and alters the fate of cells from adipocytes to osteoblasts in adipose-derived MSCs. Chitosan-conjugated AuNPs increased the calcium deposit and the mRNA expression of osteogenic genes in human adipose-derived MSCs. Furthermore, immunofluorescence and Western blotting results indicate that the enhanced osteogenic effect is induced by the activation of the Wnt/ $ \\beta $-catenin signaling pathway. $ ^{[180]} $", "page_width": 1191, "page_height": 1565, "role": "body_paragraph", "role_confidence": 0.6, "evidence": ["default body_paragraph for text label"], "seed_role": "body_paragraph", "seed_confidence": 0.6, "seed_evidence": ["default body_paragraph for text label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "STIXMath-Italic", "flags": 6, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "STIXMath-Italic", "flags": 6, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "STIXMath-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "STIXMath-Italic", "flags": 6, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "STIXMath-Italic", "flags": 6, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "STIXMath-Italic", "flags": 6, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "STIXMath-Italic", "flags": 6, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "STIXMath-Italic", "flags": 6, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "STIXMath-Italic", "flags": 6, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 12, "page": 20, "raw_label": "text", "text": "The Wnt/ $ \\beta $-catenin signaling pathway is recognized as a crucial signal for the regulation of stem cell osteogenic differentiation and is strongly associated with the formation and regeneration of bone. The binding of canonical Wnt proteins to the Frizzled/LRP receptor leads to the activation of $ \\beta $-catenin, ultimately regulating the expression of osteogenic transcription factors. The combination of non-canonical Wnt proteins with the Frizzled receptor activates heterotrimeric G protein and regulates intracellular Ca $ ^{2+} $ signaling through $ \\beta $-catenin independent pathways. The osteogenic functions of some materials are closely related to this signaling pathway. It has been shown that a PCL nanofiber scaffold promotes human MSCs adhesion and proliferation and significantly increases the osteogenic differentiation potency of MSCs by consistently activating the Wnt/ $ \\beta $-catenin and Smad3 pathways. $ ^{[178]} $ Silk braids with mechanical stiffness comparable to that of trabecular bone promoted human preosteoblast differentiation within their 3D microenvironment by the activation of Wnt/ $ \\beta $-catenin signaling. $ ^{[179]} $ The Wnt/ $ \\beta $-catenin pathway suppresses the adipogenic differentiation potential and alters the fate of cells from adipocytes to osteoblasts in adipose-derived MSCs. Chitosan-conjugated AuNPs increased the calcium deposit and the mRNA expression of osteogenic genes in human adipose-derived MSCs. Furthermore, immunofluorescence and Western blotting results indicate that the enhanced osteogenic effect is induced by the activation of the Wnt/ $ \\beta $-catenin signaling pathway. $ ^{[180]} $", "bbox": [600, 762, 1093, 1336], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "The Wnt/ $ \\beta $-catenin signaling pathway is recognized as a crucial signal for the regulation of stem cell osteogenic differentiation and is strongly associated with the formation and regeneration of bone. The binding of canonical Wnt proteins to the Frizzled/LRP receptor leads to the activation of $ \\beta $-catenin, ultimately regulating the expression of osteogenic transcription factors. The combination of non-canonical Wnt proteins with the Frizzled receptor activates heterotrimeric G protein and regulates intracellular Ca $ ^{2+} $ signaling through $ \\beta $-catenin independent pathways. The osteogenic functions of some materials are closely related to this signaling pathway. It has been shown that a PCL nanofiber scaffold promotes human MSCs adhesion and proliferation and significantly increases the osteogenic differentiation potency of MSCs by consistently activating the Wnt/ $ \\beta $-catenin and Smad3 pathways. $ ^{[178]} $ Silk braids with mechanical stiffness comparable to that of trabecular bone promoted human preosteoblast differentiation within their 3D microenvironment by the activation of Wnt/ $ \\beta $-catenin signaling. $ ^{[179]} $ The Wnt/ $ \\beta $-catenin pathway suppresses the adipogenic differentiation potential and alters the fate of cells from adipocytes to osteoblasts in adipose-derived MSCs. Chitosan-conjugated AuNPs increased the calcium deposit and the mRNA expression of osteogenic genes in human adipose-derived MSCs. Furthermore, immunofluorescence and Western blotting results indicate that the enhanced osteogenic effect is induced by the activation of the Wnt/ $ \\beta $-catenin signaling pathway. $ ^{[180]} $"}, "layout_signature": {"width": 493, "width_bucket": 500, "height": 574, "left": 600, "top": 762, "right": 1093, "bottom": 1336, "x_center": 846.5, "x_center_bucket": 850, "y_center": 1049.0, "x_ratio": 0.7107, "y_ratio": 0.6703, "width_ratio": 0.4139, "height_ratio": 0.3668, "line_count": 1}, "span_signature": {"font_size": 8.83, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaPro-Regular", "bold": false, "italic": true, "span_count": 234}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_142", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "zone": "body_zone", "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 20, "block_id": 13, "raw_label": "paragraph_title", "raw_order": 11, "bbox": [602, 1355, 836, 1379], "text": "4.2.3. Notch Signaling Pathway", "page_width": 1191, "page_height": 1565, "role": "sub_subsection_heading", "role_confidence": 0.85, "evidence": ["paragraph_title label with numbering: 4.2.3. Notch Signaling Pathway"], "seed_role": "sub_subsection_heading", "seed_confidence": 0.85, "seed_evidence": ["paragraph_title label with numbering: 4.2.3. Notch Signaling Pathway"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaSansPro-Italic", "flags": 6, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 13, "page": 20, "raw_label": "paragraph_title", "text": "4.2.3. Notch Signaling Pathway", "bbox": [602, 1355, 836, 1379], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "heading_numbered", "raw_marker": "4.2.3", "number": "4.2.3", "kind": "heading", "normalized_text": "4.2.3. Notch Signaling Pathway"}, "layout_signature": {"width": 234, "width_bucket": 225, "height": 24, "left": 602, "top": 1355, "right": 836, "bottom": 1379, "x_center": 719.0, "x_center_bucket": 725, "y_center": 1367.0, "x_ratio": 0.6037, "y_ratio": 0.8735, "width_ratio": 0.1965, "height_ratio": 0.0153, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaSansPro-Italic", "bold": false, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_136", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "zone": "body_zone", "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 20, "block_id": 14, "raw_label": "text", "raw_order": 12, "bbox": [600, 1398, 1092, 1444], "text": "Notch signaling is a highly persistent pathway associated with cell signal transduction, self-renewal potential and proliferation,", "page_width": 1191, "page_height": 1565, "role": "body_paragraph", "role_confidence": 0.6, "evidence": ["default body_paragraph for text label"], "seed_role": "body_paragraph", "seed_confidence": 0.6, "seed_evidence": ["default body_paragraph for text label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 14, "page": 20, "raw_label": "text", "text": "Notch signaling is a highly persistent pathway associated with cell signal transduction, self-renewal potential and proliferation,", "bbox": [600, 1398, 1092, 1444], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "Notch signaling is a highly persistent pathway associated with cell signal transduction, self-renewal potential and proliferation,"}, "layout_signature": {"width": 492, "width_bucket": 500, "height": 46, "left": 600, "top": 1398, "right": 1092, "bottom": 1444, "x_center": 846.0, "x_center_bucket": 850, "y_center": 1421.0, "x_ratio": 0.7103, "y_ratio": 0.908, "width_ratio": 0.4131, "height_ratio": 0.0294, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaPro-Regular", "bold": false, "italic": true, "span_count": 18}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_136", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "zone": "body_zone", "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 20, "block_id": 15, "raw_label": "footer", "raw_order": null, "bbox": [94, 1487, 283, 1505], "text": "Small Methods 2024, 8, 2301283", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["footer label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["footer label"], "span_metadata": [{"size": 6.973800182342529, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 15, "page": 20, "raw_label": "footer", "text": "Small Methods 2024, 8, 2301283", "bbox": [94, 1487, 283, 1505], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "Small Methods 2024, 8, 2301283"}, "layout_signature": {"width": 189, "width_bucket": 200, "height": 18, "left": 94, "top": 1487, "right": 283, "bottom": 1505, "x_center": 188.5, "x_center_bucket": 200, "y_center": 1496.0, "x_ratio": 0.1583, "y_ratio": 0.9559, "width_ratio": 0.1587, "height_ratio": 0.0115, "line_count": 1}, "span_signature": {"font_size": 6.97, "font_size_median": 6.97, "font_size_bucket": 7.0, "font_family_norm": "ScalaSansPro-Italic", "bold": true, "italic": true, "span_count": 5}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_136", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 20, "block_id": 16, "raw_label": "footer", "raw_order": null, "bbox": [520, 1484, 663, 1507], "text": "2301283 (20 of 27)", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.9, "evidence": ["footer label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["footer label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaSansPro-Bold", "flags": 20, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 16, "page": 20, "raw_label": "footer", "text": "2301283 (20 of 27)", "bbox": [520, 1484, 663, 1507], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_dot", "raw_marker": "2301283", "number": 2301283, "kind": "reference", "normalized_text": "2301283 (20 of 27)"}, "layout_signature": {"width": 143, "width_bucket": 150, "height": 23, "left": 520, "top": 1484, "right": 663, "bottom": 1507, "x_center": 591.5, "x_center_bucket": 600, "y_center": 1495.5, "x_ratio": 0.4966, "y_ratio": 0.9556, "width_ratio": 0.1201, "height_ratio": 0.0147, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaSansPro-Bold", "bold": true, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_family_anchor", "reading_band_id": "band_136", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 20, "block_id": 17, "raw_label": "footer", "raw_order": null, "bbox": [932, 1487, 1090, 1506], "text": "© 2024 Wiley-VCH GmbH", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["footer label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["footer label"], "span_metadata": [{"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 17, "page": 20, "raw_label": "footer", "text": "© 2024 Wiley-VCH GmbH", "bbox": [932, 1487, 1090, 1506], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "© 2024 Wiley-VCH GmbH"}, "layout_signature": {"width": 158, "width_bucket": 150, "height": 19, "left": 932, "top": 1487, "right": 1090, "bottom": 1506, "x_center": 1011.0, "x_center_bucket": 1000, "y_center": 1496.5, "x_ratio": 0.8489, "y_ratio": 0.9562, "width_ratio": 0.1327, "height_ratio": 0.0121, "line_count": 1}, "span_signature": {"font_size": 6.97, "font_size_median": 6.97, "font_size_bucket": 7.0, "font_family_norm": "ScalaSansPro-Regular", "bold": false, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_136", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 20, "block_id": 18, "raw_label": "aside_text", "raw_order": null, "bbox": [1154, 29, 1172, 1533], "text": "2369608, 2024, 8, Downloaded from https://ontinelibrary.wiley.com/doi/10.1002/smid.202301283 by Shandong University Library, Wiley Online Library on [18/02/2026]. See the Terms and Conditions (https://ontinelibrary.wiley.com/terms-and-conditions) on Wiley Online Library for rules of use; OA articles are governed by the applicable Creative Commons License.", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.95, "evidence": ["margin-band narrow/tall geometry; treated as noise"], "seed_role": "noise", "seed_confidence": 0.95, "seed_evidence": ["margin-band narrow/tall geometry; treated as noise"], "span_metadata": [{"size": 5.03000020980835, "font": "Times-Roman", "flags": 4, "color": 0, "dir": [0.0, 1.0], "wmode": 0}], "raw_observation": {"block_id": 18, "page": 20, "raw_label": "aside_text", "text": "2369608, 2024, 8, Downloaded from https://ontinelibrary.wiley.com/doi/10.1002/smid.202301283 by Shandong University Library, Wiley Online Library on [18/02/2026]. See the Terms and Conditions (https://ontinelibrary.wiley.com/terms-and-conditions) on Wiley Online Library for rules of use; OA articles are governed by the applicable Creative Commons License.", "bbox": [1154, 29, 1172, 1533], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "2369608, 2024, 8, Downloaded from https://ontinelibrary.wiley.com/doi/10.1002/smid.202301283 by Shandong University Library, Wiley Online Library on [18/02/2026]. See the Terms and Conditions (https://ontinelibrary.wiley.com/terms-and-conditions) on Wiley Online Library for rules of use; OA articles are governed by the applicable Creative Commons License."}, "layout_signature": {"width": 18, "width_bucket": 25, "height": 1504, "left": 1154, "top": 29, "right": 1172, "bottom": 1533, "x_center": 1163.0, "x_center_bucket": 1175, "y_center": 781.0, "x_ratio": 0.9765, "y_ratio": 0.499, "width_ratio": 0.0151, "height_ratio": 0.961, "line_count": 1}, "span_signature": {"font_size": 5.03, "font_size_median": 5.03, "font_size_bucket": 5.0, "font_family_norm": "Times-Roman", "bold": false, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_136", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 21, "block_id": 0, "raw_label": "header", "raw_order": null, "bbox": [98, 45, 346, 117], "text": "ADVANCED\nSCIENCE NEWS\nwww.advancedsciencenews.com", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["header label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["header label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaSansPro-Bold", "flags": 20, "color": 255, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 0, "page": 21, "raw_label": "header", "text": "ADVANCED\nSCIENCE NEWS\nwww.advancedsciencenews.com", "bbox": [98, 45, 346, 117], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "ADVANCED\nSCIENCE NEWS\nwww.advancedsciencenews.com"}, "layout_signature": {"width": 248, "width_bucket": 250, "height": 72, "left": 98, "top": 45, "right": 346, "bottom": 117, "x_center": 222.0, "x_center_bucket": 225, "y_center": 81.0, "x_ratio": 0.1864, "y_ratio": 0.0518, "width_ratio": 0.2082, "height_ratio": 0.046, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaSansPro-Bold", "bold": true, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 21, "block_id": 1, "raw_label": "header", "raw_order": null, "bbox": [901, 36, 1097, 117], "text": "small methods\nwww.small-methods.com", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["header label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["header label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaSansPro-Bold", "flags": 20, "color": 255, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 1, "page": 21, "raw_label": "header", "text": "small methods\nwww.small-methods.com", "bbox": [901, 36, 1097, 117], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "small methods\nwww.small-methods.com"}, "layout_signature": {"width": 196, "width_bucket": 200, "height": 81, "left": 901, "top": 36, "right": 1097, "bottom": 117, "x_center": 999.0, "x_center_bucket": 1000, "y_center": 76.5, "x_ratio": 0.8388, "y_ratio": 0.0489, "width_ratio": 0.1646, "height_ratio": 0.0518, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaSansPro-Bold", "bold": true, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_142", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 21, "block_id": 2, "raw_label": "figure_title", "raw_order": null, "bbox": [105, 163, 133, 187], "text": "(A)", "page_width": 1191, "page_height": 1565, "role": "figure_inner_text", "role_confidence": 0.9, "evidence": ["panel label / figure inner text: (A)"], "seed_role": "figure_inner_text", "seed_confidence": 0.9, "seed_evidence": ["panel label / figure inner text: (A)"], "span_metadata": null, "raw_observation": {"block_id": 2, "page": 21, "raw_label": "figure_title", "text": "(A)", "bbox": [105, 163, 133, 187], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "panel_label", "raw_marker": "(A)", "number": null, "kind": "panel_label", "normalized_text": "(A)"}, "layout_signature": {"width": 28, "width_bucket": 25, "height": 24, "left": 105, "top": 163, "right": 133, "bottom": 187, "x_center": 119.0, "x_center_bucket": 125, "y_center": 175.0, "x_ratio": 0.0999, "y_ratio": 0.1118, "width_ratio": 0.0235, "height_ratio": 0.0153, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "display_zone", "style_family": "legend_like", "style_family_authority": "figure_marker", "reading_band_id": "band_142", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 21, "block_id": 3, "raw_label": "image", "raw_order": null, "bbox": [106, 156, 654, 485], "text": "", "page_width": 1191, "page_height": 1565, "role": "figure_asset", "role_confidence": 0.85, "evidence": ["media label: image"], "seed_role": "media_asset", "seed_confidence": 0.85, "seed_evidence": ["media label: image"], "span_metadata": null, "raw_observation": {"block_id": 3, "page": 21, "raw_label": "image", "text": "", "bbox": [106, 156, 654, 485], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "empty", "raw_marker": null, "number": null, "kind": null, "normalized_text": ""}, "layout_signature": {"width": 548, "width_bucket": 550, "height": 329, "left": 106, "top": 156, "right": 654, "bottom": 485, "x_center": 380.0, "x_center_bucket": 375, "y_center": 320.5, "x_ratio": 0.3191, "y_ratio": 0.2048, "width_ratio": 0.4601, "height_ratio": 0.2102, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_139", "display_cluster_candidate_id": "disp_27_0", "layout_region": "display_zone", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.0, "decision": "body", "evidence": []}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"], "asset_family_hint": "figure_like", "asset_family_confidence": 0.7, "asset_family_evidence": ["raw_label:image"]}
+{"paper_id": "2HEUD5P9", "page": 21, "block_id": 4, "raw_label": "figure_title", "raw_order": null, "bbox": [106, 500, 135, 524], "text": "(C)", "page_width": 1191, "page_height": 1565, "role": "figure_inner_text", "role_confidence": 0.9, "evidence": ["panel label / figure inner text: (C)"], "seed_role": "figure_inner_text", "seed_confidence": 0.9, "seed_evidence": ["panel label / figure inner text: (C)"], "span_metadata": null, "raw_observation": {"block_id": 4, "page": 21, "raw_label": "figure_title", "text": "(C)", "bbox": [106, 500, 135, 524], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "panel_label", "raw_marker": "(C)", "number": null, "kind": "panel_label", "normalized_text": "(C)"}, "layout_signature": {"width": 29, "width_bucket": 25, "height": 24, "left": 106, "top": 500, "right": 135, "bottom": 524, "x_center": 120.5, "x_center_bucket": 125, "y_center": 512.0, "x_ratio": 0.1012, "y_ratio": 0.3272, "width_ratio": 0.0243, "height_ratio": 0.0153, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "display_zone", "style_family": "legend_like", "style_family_authority": "figure_marker", "reading_band_id": "band_140", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 21, "block_id": 5, "raw_label": "image", "raw_order": null, "bbox": [671, 160, 1088, 478], "text": "", "page_width": 1191, "page_height": 1565, "role": "figure_asset", "role_confidence": 0.85, "evidence": ["media label: image"], "seed_role": "media_asset", "seed_confidence": 0.85, "seed_evidence": ["media label: image"], "span_metadata": null, "raw_observation": {"block_id": 5, "page": 21, "raw_label": "image", "text": "", "bbox": [671, 160, 1088, 478], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "empty", "raw_marker": null, "number": null, "kind": null, "normalized_text": ""}, "layout_signature": {"width": 417, "width_bucket": 425, "height": 318, "left": 671, "top": 160, "right": 1088, "bottom": 478, "x_center": 879.5, "x_center_bucket": 875, "y_center": 319.0, "x_ratio": 0.7385, "y_ratio": 0.2038, "width_ratio": 0.3501, "height_ratio": 0.2032, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_139", "display_cluster_candidate_id": "disp_27_0", "layout_region": "display_zone", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"], "asset_family_hint": "figure_like", "asset_family_confidence": 0.7, "asset_family_evidence": ["raw_label:image"]}
+{"paper_id": "2HEUD5P9", "page": 21, "block_id": 6, "raw_label": "chart", "raw_order": null, "bbox": [279, 515, 419, 651], "text": "", "page_width": 1191, "page_height": 1565, "role": "figure_asset", "role_confidence": 0.85, "evidence": ["media label: chart"], "seed_role": "media_asset", "seed_confidence": 0.85, "seed_evidence": ["media label: chart"], "span_metadata": null, "raw_observation": {"block_id": 6, "page": 21, "raw_label": "chart", "text": "", "bbox": [279, 515, 419, 651], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "empty", "raw_marker": null, "number": null, "kind": null, "normalized_text": ""}, "layout_signature": {"width": 140, "width_bucket": 150, "height": 136, "left": 279, "top": 515, "right": 419, "bottom": 651, "x_center": 349.0, "x_center_bucket": 350, "y_center": 583.0, "x_ratio": 0.293, "y_ratio": 0.3725, "width_ratio": 0.1175, "height_ratio": 0.0869, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_140", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"], "asset_family_hint": "figure_like", "asset_family_confidence": 0.7, "asset_family_evidence": ["raw_label:chart"]}
+{"paper_id": "2HEUD5P9", "page": 21, "block_id": 7, "raw_label": "chart", "raw_order": null, "bbox": [419, 514, 576, 650], "text": "", "page_width": 1191, "page_height": 1565, "role": "figure_asset", "role_confidence": 0.85, "evidence": ["media label: chart"], "seed_role": "media_asset", "seed_confidence": 0.85, "seed_evidence": ["media label: chart"], "span_metadata": null, "raw_observation": {"block_id": 7, "page": 21, "raw_label": "chart", "text": "", "bbox": [419, 514, 576, 650], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "empty", "raw_marker": null, "number": null, "kind": null, "normalized_text": ""}, "layout_signature": {"width": 157, "width_bucket": 150, "height": 136, "left": 419, "top": 514, "right": 576, "bottom": 650, "x_center": 497.5, "x_center_bucket": 500, "y_center": 582.0, "x_ratio": 0.4177, "y_ratio": 0.3719, "width_ratio": 0.1318, "height_ratio": 0.0869, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_139", "display_cluster_candidate_id": "disp_27_0", "layout_region": "display_zone", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"], "asset_family_hint": "figure_like", "asset_family_confidence": 0.7, "asset_family_evidence": ["raw_label:chart"]}
+{"paper_id": "2HEUD5P9", "page": 21, "block_id": 8, "raw_label": "figure_title", "raw_order": null, "bbox": [559, 493, 587, 515], "text": "(D)", "page_width": 1191, "page_height": 1565, "role": "figure_inner_text", "role_confidence": 0.9, "evidence": ["panel label / figure inner text: (D)"], "seed_role": "figure_inner_text", "seed_confidence": 0.9, "seed_evidence": ["panel label / figure inner text: (D)"], "span_metadata": null, "raw_observation": {"block_id": 8, "page": 21, "raw_label": "figure_title", "text": "(D)", "bbox": [559, 493, 587, 515], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "panel_label", "raw_marker": "(D)", "number": null, "kind": "panel_label", "normalized_text": "(D)"}, "layout_signature": {"width": 28, "width_bucket": 25, "height": 22, "left": 559, "top": 493, "right": 587, "bottom": 515, "x_center": 573.0, "x_center_bucket": 575, "y_center": 504.0, "x_ratio": 0.4811, "y_ratio": 0.322, "width_ratio": 0.0235, "height_ratio": 0.0141, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "display_zone", "style_family": "legend_like", "style_family_authority": "figure_marker", "reading_band_id": "band_140", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 21, "block_id": 9, "raw_label": "chart", "raw_order": null, "bbox": [127, 655, 273, 796], "text": "", "page_width": 1191, "page_height": 1565, "role": "figure_asset", "role_confidence": 0.85, "evidence": ["media label: chart"], "seed_role": "media_asset", "seed_confidence": 0.85, "seed_evidence": ["media label: chart"], "span_metadata": null, "raw_observation": {"block_id": 9, "page": 21, "raw_label": "chart", "text": "", "bbox": [127, 655, 273, 796], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "empty", "raw_marker": null, "number": null, "kind": null, "normalized_text": ""}, "layout_signature": {"width": 146, "width_bucket": 150, "height": 141, "left": 127, "top": 655, "right": 273, "bottom": 796, "x_center": 200.0, "x_center_bucket": 200, "y_center": 725.5, "x_ratio": 0.1679, "y_ratio": 0.4636, "width_ratio": 0.1226, "height_ratio": 0.0901, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_138", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"], "asset_family_hint": "figure_like", "asset_family_confidence": 0.7, "asset_family_evidence": ["raw_label:chart"]}
+{"paper_id": "2HEUD5P9", "page": 21, "block_id": 10, "raw_label": "chart", "raw_order": null, "bbox": [273, 658, 419, 793], "text": "", "page_width": 1191, "page_height": 1565, "role": "figure_asset", "role_confidence": 0.85, "evidence": ["media label: chart"], "seed_role": "media_asset", "seed_confidence": 0.85, "seed_evidence": ["media label: chart"], "span_metadata": null, "raw_observation": {"block_id": 10, "page": 21, "raw_label": "chart", "text": "", "bbox": [273, 658, 419, 793], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "empty", "raw_marker": null, "number": null, "kind": null, "normalized_text": ""}, "layout_signature": {"width": 146, "width_bucket": 150, "height": 135, "left": 273, "top": 658, "right": 419, "bottom": 793, "x_center": 346.0, "x_center_bucket": 350, "y_center": 725.5, "x_ratio": 0.2905, "y_ratio": 0.4636, "width_ratio": 0.1226, "height_ratio": 0.0863, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_141", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "hard", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"], "asset_family_hint": "figure_like", "asset_family_confidence": 0.7, "asset_family_evidence": ["raw_label:chart"]}
+{"paper_id": "2HEUD5P9", "page": 21, "block_id": 11, "raw_label": "chart", "raw_order": null, "bbox": [420, 658, 563, 793], "text": "", "page_width": 1191, "page_height": 1565, "role": "figure_asset", "role_confidence": 0.85, "evidence": ["media label: chart"], "seed_role": "media_asset", "seed_confidence": 0.85, "seed_evidence": ["media label: chart"], "span_metadata": null, "raw_observation": {"block_id": 11, "page": 21, "raw_label": "chart", "text": "", "bbox": [420, 658, 563, 793], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "empty", "raw_marker": null, "number": null, "kind": null, "normalized_text": ""}, "layout_signature": {"width": 143, "width_bucket": 150, "height": 135, "left": 420, "top": 658, "right": 563, "bottom": 793, "x_center": 491.5, "x_center_bucket": 500, "y_center": 725.5, "x_ratio": 0.4127, "y_ratio": 0.4636, "width_ratio": 0.1201, "height_ratio": 0.0863, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_142", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"], "asset_family_hint": "figure_like", "asset_family_confidence": 0.7, "asset_family_evidence": ["raw_label:chart"]}
+{"paper_id": "2HEUD5P9", "page": 21, "block_id": 12, "raw_label": "image", "raw_order": null, "bbox": [594, 499, 1079, 834], "text": "", "page_width": 1191, "page_height": 1565, "role": "figure_asset", "role_confidence": 0.85, "evidence": ["media label: image"], "seed_role": "media_asset", "seed_confidence": 0.85, "seed_evidence": ["media label: image"], "span_metadata": null, "raw_observation": {"block_id": 12, "page": 21, "raw_label": "image", "text": "", "bbox": [594, 499, 1079, 834], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "empty", "raw_marker": null, "number": null, "kind": null, "normalized_text": ""}, "layout_signature": {"width": 485, "width_bucket": 475, "height": 335, "left": 594, "top": 499, "right": 1079, "bottom": 834, "x_center": 836.5, "x_center_bucket": 825, "y_center": 666.5, "x_ratio": 0.7024, "y_ratio": 0.4259, "width_ratio": 0.4072, "height_ratio": 0.2141, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_142", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"], "asset_family_hint": "figure_like", "asset_family_confidence": 0.7, "asset_family_evidence": ["raw_label:image"]}
+{"paper_id": "2HEUD5P9", "page": 21, "block_id": 13, "raw_label": "figure_title", "raw_order": null, "bbox": [105, 819, 133, 842], "text": "(E)", "page_width": 1191, "page_height": 1565, "role": "figure_inner_text", "role_confidence": 0.9, "evidence": ["panel label / figure inner text: (E)"], "seed_role": "figure_inner_text", "seed_confidence": 0.9, "seed_evidence": ["panel label / figure inner text: (E)"], "span_metadata": null, "raw_observation": {"block_id": 13, "page": 21, "raw_label": "figure_title", "text": "(E)", "bbox": [105, 819, 133, 842], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "panel_label", "raw_marker": "(E)", "number": null, "kind": "panel_label", "normalized_text": "(E)"}, "layout_signature": {"width": 28, "width_bucket": 25, "height": 23, "left": 105, "top": 819, "right": 133, "bottom": 842, "x_center": 119.0, "x_center_bucket": 125, "y_center": 830.5, "x_ratio": 0.0999, "y_ratio": 0.5307, "width_ratio": 0.0235, "height_ratio": 0.0147, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "display_zone", "style_family": "legend_like", "style_family_authority": "figure_marker", "reading_band_id": "band_136", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 21, "block_id": 14, "raw_label": "image", "raw_order": null, "bbox": [112, 818, 587, 1200], "text": "", "page_width": 1191, "page_height": 1565, "role": "figure_asset", "role_confidence": 0.85, "evidence": ["media label: image"], "seed_role": "media_asset", "seed_confidence": 0.85, "seed_evidence": ["media label: image"], "span_metadata": null, "raw_observation": {"block_id": 14, "page": 21, "raw_label": "image", "text": "", "bbox": [112, 818, 587, 1200], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "empty", "raw_marker": null, "number": null, "kind": null, "normalized_text": ""}, "layout_signature": {"width": 475, "width_bucket": 475, "height": 382, "left": 112, "top": 818, "right": 587, "bottom": 1200, "x_center": 349.5, "x_center_bucket": 350, "y_center": 1009.0, "x_ratio": 0.2935, "y_ratio": 0.6447, "width_ratio": 0.3988, "height_ratio": 0.2441, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_136", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"], "asset_family_hint": "figure_like", "asset_family_confidence": 0.7, "asset_family_evidence": ["raw_label:image"]}
+{"paper_id": "2HEUD5P9", "page": 21, "block_id": 15, "raw_label": "figure_title", "raw_order": null, "bbox": [588, 852, 614, 875], "text": "(F)", "page_width": 1191, "page_height": 1565, "role": "figure_inner_text", "role_confidence": 0.9, "evidence": ["panel label / figure inner text: (F)"], "seed_role": "figure_inner_text", "seed_confidence": 0.9, "seed_evidence": ["panel label / figure inner text: (F)"], "span_metadata": null, "raw_observation": {"block_id": 15, "page": 21, "raw_label": "figure_title", "text": "(F)", "bbox": [588, 852, 614, 875], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "panel_label", "raw_marker": "(F)", "number": null, "kind": "panel_label", "normalized_text": "(F)"}, "layout_signature": {"width": 26, "width_bucket": 25, "height": 23, "left": 588, "top": 852, "right": 614, "bottom": 875, "x_center": 601.0, "x_center_bucket": 600, "y_center": 863.5, "x_ratio": 0.5046, "y_ratio": 0.5518, "width_ratio": 0.0218, "height_ratio": 0.0147, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "display_zone", "style_family": "legend_like", "style_family_authority": "figure_marker", "reading_band_id": "band_136", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 21, "block_id": 16, "raw_label": "image", "raw_order": null, "bbox": [630, 859, 1043, 1192], "text": "", "page_width": 1191, "page_height": 1565, "role": "figure_asset", "role_confidence": 0.85, "evidence": ["media label: image"], "seed_role": "media_asset", "seed_confidence": 0.85, "seed_evidence": ["media label: image"], "span_metadata": null, "raw_observation": {"block_id": 16, "page": 21, "raw_label": "image", "text": "", "bbox": [630, 859, 1043, 1192], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "empty", "raw_marker": null, "number": null, "kind": null, "normalized_text": ""}, "layout_signature": {"width": 413, "width_bucket": 425, "height": 333, "left": 630, "top": 859, "right": 1043, "bottom": 1192, "x_center": 836.5, "x_center_bucket": 825, "y_center": 1025.5, "x_ratio": 0.7024, "y_ratio": 0.6553, "width_ratio": 0.3468, "height_ratio": 0.2128, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_136", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"], "asset_family_hint": "figure_like", "asset_family_confidence": 0.7, "asset_family_evidence": ["raw_label:image"]}
+{"paper_id": "2HEUD5P9", "page": 21, "block_id": 17, "raw_label": "figure_title", "raw_order": null, "bbox": [96, 1216, 1100, 1353], "text": "Figure 8. A) Schematic illustration of the procedure to fabricate BP@BMP2 electrospun fibrous scaffolds and the effect of recruiting osteoblasts and releasing calcium-free phosphate therapy for promoting bone physiological regeneration in vivo. B) Radiological analysis in vivo. Representative microCT reconstruction images in coronal and sagittal view at 4 and 8 weeks in different groups. While the initial boundary of critical cranial defect was marked by the red dotted lines. $ ^{[177]} $ Copyright 2020 Wiley-VCH. C) Quantitative RT-qPCR result of in vivo BCP ceramic implantation. $ ^{[183]} $ Copyright 2020 Wiley-VCH. D) Proposed signaling pathways (PI3K/Akt-mTOR) that influence BMDMs polarization. $ ^{[186]} $ Copyright 2022 Elsevier. E) The possible signaling pathways for the exosome-induced osteogenic differentiation of hMSCs by the PI3K/Akt and MAPK signaling pathways. $ ^{[101]} $ Copyright 2020 Wiley-VCH. F) Schematic model of matrix dynamics regulating BMSC differentiation by integrin $ \\beta $1-induced activation of YAP. $ ^{[188]} $ Copyright 2022 Elsevier.", "page_width": 1191, "page_height": 1565, "role": "figure_caption", "role_confidence": 0.92, "evidence": ["figure_title label: Figure 8. A) Schematic illustration of the procedure to fabr"], "seed_role": "figure_caption", "seed_confidence": 0.92, "seed_evidence": ["figure_title label: Figure 8. A) Schematic illustration of the procedure to fabr"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaSansPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaSansPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaSansPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaSansPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaSansPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaSansPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaSansPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaSansPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaSansPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaSansPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaSansPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaSansPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "STIXMath-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaSansPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaSansPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaSansPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 17, "page": 21, "raw_label": "figure_title", "text": "Figure 8. A) Schematic illustration of the procedure to fabricate BP@BMP2 electrospun fibrous scaffolds and the effect of recruiting osteoblasts and releasing calcium-free phosphate therapy for promoting bone physiological regeneration in vivo. B) Radiological analysis in vivo. Representative microCT reconstruction images in coronal and sagittal view at 4 and 8 weeks in different groups. While the initial boundary of critical cranial defect was marked by the red dotted lines. $ ^{[177]} $ Copyright 2020 Wiley-VCH. C) Quantitative RT-qPCR result of in vivo BCP ceramic implantation. $ ^{[183]} $ Copyright 2020 Wiley-VCH. D) Proposed signaling pathways (PI3K/Akt-mTOR) that influence BMDMs polarization. $ ^{[186]} $ Copyright 2022 Elsevier. E) The possible signaling pathways for the exosome-induced osteogenic differentiation of hMSCs by the PI3K/Akt and MAPK signaling pathways. $ ^{[101]} $ Copyright 2020 Wiley-VCH. F) Schematic model of matrix dynamics regulating BMSC differentiation by integrin $ \\beta $1-induced activation of YAP. $ ^{[188]} $ Copyright 2022 Elsevier.", "bbox": [96, 1216, 1100, 1353], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "figure_number", "raw_marker": "Figure 8", "number": 8, "kind": "figure", "normalized_text": "Figure 8. A) Schematic illustration of the procedure to fabricate BP@BMP2 electrospun fibrous scaffolds and the effect of recruiting osteoblasts and releasing calcium-free phosphate therapy for promoting bone physiological regeneration in vivo. B) Radiological analysis in vivo. Representative microCT reconstruction images in coronal and sagittal view at 4 and 8 weeks in different groups. While the initial boundary of critical cranial defect was marked by the red dotted lines. $ ^{[177]} $ Copyright 2020 Wiley-VCH. C) Quantitative RT-qPCR result of in vivo BCP ceramic implantation. $ ^{[183]} $ Copyright 2020 Wiley-VCH. D) Proposed signaling pathways (PI3K/Akt-mTOR) that influence BMDMs polarization. $ ^{[186]} $ Copyright 2022 Elsevier. E) The possible signaling pathways for the exosome-induced osteogenic differentiation of hMSCs by the PI3K/Akt and MAPK signaling pathways. $ ^{[101]} $ Copyright 2020 Wiley-VCH. F) Schematic model of matrix dynamics regulating BMSC differentiation by integrin $ \\beta $1-induced activation of YAP. $ ^{[188]} $ Copyright 2022 Elsevier."}, "layout_signature": {"width": 1004, "width_bucket": 1000, "height": 137, "left": 96, "top": 1216, "right": 1100, "bottom": 1353, "x_center": 598.0, "x_center_bucket": 600, "y_center": 1284.5, "x_ratio": 0.5021, "y_ratio": 0.8208, "width_ratio": 0.843, "height_ratio": 0.0875, "line_count": 1}, "span_signature": {"font_size": 7.52, "font_size_median": 7.97, "font_size_bucket": 7.5, "font_family_norm": "ScalaSansPro-Bold", "bold": true, "italic": true, "span_count": 66}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "display_zone", "style_family": "legend_like", "style_family_authority": "figure_marker", "reading_band_id": "band_136", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.0, "decision": "body", "evidence": []}, "role_verification_status": "ACCEPT", "role_source": "accepted_figure_caption_artifact", "role_evidence": ["figure caption matched accepted figure artifact"]}
+{"paper_id": "2HEUD5P9", "page": 21, "block_id": 18, "raw_label": "footer", "raw_order": null, "bbox": [99, 1487, 289, 1505], "text": "Small Methods 2024, 8, 2301283", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["footer label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["footer label"], "span_metadata": [{"size": 6.973800182342529, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 18, "page": 21, "raw_label": "footer", "text": "Small Methods 2024, 8, 2301283", "bbox": [99, 1487, 289, 1505], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "Small Methods 2024, 8, 2301283"}, "layout_signature": {"width": 190, "width_bucket": 200, "height": 18, "left": 99, "top": 1487, "right": 289, "bottom": 1505, "x_center": 194.0, "x_center_bucket": 200, "y_center": 1496.0, "x_ratio": 0.1629, "y_ratio": 0.9559, "width_ratio": 0.1595, "height_ratio": 0.0115, "line_count": 1}, "span_signature": {"font_size": 6.97, "font_size_median": 6.97, "font_size_bucket": 7.0, "font_family_norm": "ScalaSansPro-Italic", "bold": true, "italic": true, "span_count": 5}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_136", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 21, "block_id": 19, "raw_label": "number", "raw_order": null, "bbox": [526, 1484, 668, 1508], "text": "2301283 (21 of 27)", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.9, "evidence": ["page number label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["page number label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaSansPro-Bold", "flags": 20, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 19, "page": 21, "raw_label": "number", "text": "2301283 (21 of 27)", "bbox": [526, 1484, 668, 1508], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_dot", "raw_marker": "2301283", "number": 2301283, "kind": "reference", "normalized_text": "2301283 (21 of 27)"}, "layout_signature": {"width": 142, "width_bucket": 150, "height": 24, "left": 526, "top": 1484, "right": 668, "bottom": 1508, "x_center": 597.0, "x_center_bucket": 600, "y_center": 1496.0, "x_ratio": 0.5013, "y_ratio": 0.9559, "width_ratio": 0.1192, "height_ratio": 0.0153, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaSansPro-Bold", "bold": true, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_family_anchor", "reading_band_id": "band_136", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 21, "block_id": 20, "raw_label": "footer", "raw_order": null, "bbox": [937, 1487, 1096, 1506], "text": "© 2024 Wiley-VCH GmbH", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["footer label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["footer label"], "span_metadata": [{"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 20, "page": 21, "raw_label": "footer", "text": "© 2024 Wiley-VCH GmbH", "bbox": [937, 1487, 1096, 1506], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "© 2024 Wiley-VCH GmbH"}, "layout_signature": {"width": 159, "width_bucket": 150, "height": 19, "left": 937, "top": 1487, "right": 1096, "bottom": 1506, "x_center": 1016.5, "x_center_bucket": 1025, "y_center": 1496.5, "x_ratio": 0.8535, "y_ratio": 0.9562, "width_ratio": 0.1335, "height_ratio": 0.0121, "line_count": 1}, "span_signature": {"font_size": 6.97, "font_size_median": 6.97, "font_size_bucket": 7.0, "font_family_norm": "ScalaSansPro-Regular", "bold": false, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_136", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 21, "block_id": 21, "raw_label": "aside_text", "raw_order": null, "bbox": [1154, 31, 1172, 1534], "text": "23699608, 2024, 8, Downloaded from https://onlinelibrary.wiley.com/doi/10.1002/smld.202301283 by Shandong University Library, Wiley Online Library on [18/02/2026]. See the Terms and Conditions (https://onlinelibrary.wiley.com/terms-and-conditions) on Wiley Online Library for rules of use; OA articles are governed by the applicable Creative Commons License", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.95, "evidence": ["margin-band narrow/tall geometry; treated as noise"], "seed_role": "noise", "seed_confidence": 0.95, "seed_evidence": ["margin-band narrow/tall geometry; treated as noise"], "span_metadata": [{"size": 5.03000020980835, "font": "Times-Roman", "flags": 4, "color": 0, "dir": [0.0, 1.0], "wmode": 0}], "raw_observation": {"block_id": 21, "page": 21, "raw_label": "aside_text", "text": "23699608, 2024, 8, Downloaded from https://onlinelibrary.wiley.com/doi/10.1002/smld.202301283 by Shandong University Library, Wiley Online Library on [18/02/2026]. See the Terms and Conditions (https://onlinelibrary.wiley.com/terms-and-conditions) on Wiley Online Library for rules of use; OA articles are governed by the applicable Creative Commons License", "bbox": [1154, 31, 1172, 1534], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "23699608, 2024, 8, Downloaded from https://onlinelibrary.wiley.com/doi/10.1002/smld.202301283 by Shandong University Library, Wiley Online Library on [18/02/2026]. See the Terms and Conditions (https://onlinelibrary.wiley.com/terms-and-conditions) on Wiley Online Library for rules of use; OA articles are governed by the applicable Creative Commons License"}, "layout_signature": {"width": 18, "width_bucket": 25, "height": 1503, "left": 1154, "top": 31, "right": 1172, "bottom": 1534, "x_center": 1163.0, "x_center_bucket": 1175, "y_center": 782.5, "x_ratio": 0.9765, "y_ratio": 0.5, "width_ratio": 0.0151, "height_ratio": 0.9604, "line_count": 1}, "span_signature": {"font_size": 5.03, "font_size_median": 5.03, "font_size_bucket": 5.0, "font_family_norm": "Times-Roman", "bold": false, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_133", "display_cluster_candidate_id": "disp_26_0", "layout_region": "display_zone", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 22, "block_id": 0, "raw_label": "header", "raw_order": null, "bbox": [92, 46, 339, 117], "text": "ADVANCED\nSCIENCE NEWS\nwww.advancedsciencenews.com", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["header label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["header label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaSansPro-Bold", "flags": 20, "color": 255, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 0, "page": 22, "raw_label": "header", "text": "ADVANCED\nSCIENCE NEWS\nwww.advancedsciencenews.com", "bbox": [92, 46, 339, 117], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "ADVANCED\nSCIENCE NEWS\nwww.advancedsciencenews.com"}, "layout_signature": {"width": 247, "width_bucket": 250, "height": 71, "left": 92, "top": 46, "right": 339, "bottom": 117, "x_center": 215.5, "x_center_bucket": 225, "y_center": 81.5, "x_ratio": 0.1809, "y_ratio": 0.0521, "width_ratio": 0.2074, "height_ratio": 0.0454, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaSansPro-Bold", "bold": true, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 22, "block_id": 1, "raw_label": "header_image", "raw_order": null, "bbox": [997, 36, 1089, 97], "text": "", "page_width": 1191, "page_height": 1565, "role": "unknown_structural", "role_confidence": 0.2, "evidence": ["unrecognized label 'header_image'"], "seed_role": "unknown_structural", "seed_confidence": 0.2, "seed_evidence": ["unrecognized label 'header_image'"], "span_metadata": null, "raw_observation": {"block_id": 1, "page": 22, "raw_label": "header_image", "text": "", "bbox": [997, 36, 1089, 97], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "empty", "raw_marker": null, "number": null, "kind": null, "normalized_text": ""}, "layout_signature": {"width": 92, "width_bucket": 100, "height": 61, "left": 997, "top": 36, "right": 1089, "bottom": 97, "x_center": 1043.0, "x_center_bucket": 1050, "y_center": 66.5, "x_ratio": 0.8757, "y_ratio": 0.0425, "width_ratio": 0.0772, "height_ratio": 0.039, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": true, "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_142", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["non-structural role accepted"]}
+{"paper_id": "2HEUD5P9", "page": 22, "block_id": 2, "raw_label": "header", "raw_order": null, "bbox": [897, 97, 1090, 117], "text": "www.small-methods.com", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["header label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["header label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaSansPro-Bold", "flags": 20, "color": 255, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 2, "page": 22, "raw_label": "header", "text": "www.small-methods.com", "bbox": [897, 97, 1090, 117], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "www.small-methods.com"}, "layout_signature": {"width": 193, "width_bucket": 200, "height": 20, "left": 897, "top": 97, "right": 1090, "bottom": 117, "x_center": 993.5, "x_center_bucket": 1000, "y_center": 107.0, "x_ratio": 0.8342, "y_ratio": 0.0684, "width_ratio": 0.162, "height_ratio": 0.0128, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaSansPro-Bold", "bold": true, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_142", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 22, "block_id": 3, "raw_label": "text", "raw_order": 1, "bbox": [89, 148, 583, 701], "text": "and skeletal development. Upon cell-cell contact, Notch ligands (Jagged and Delta) interact with Notch receptors (Notch1–4), leading to the cleavage of the Notch intracellular domain. Subsequently, the Notch intracellular domain translocates to the nucleus, and the binding of the Notch intracellular domain to the DNA-binding protein CBF1, Suppressor of Hairless, Lag-1 (CSL) activates the transcription of Notch target genes. Activation of Notch signaling in human bone marrow MSCs stimulates early osteogenic differentiation while suppressing mature osteoblast formation by inhibiting Runx2 activity. Notch2 signaling modulates osteogenic differentiation initiated by BMP and Wnt signaling pathways. Overexpressed Notch intracellular domain inhibits BMP2-mediated Runx2 transcriptional activity and the Wnt-dependent osteogenesis pathway. $ ^{[181]} $ Silk fibroin, a core structural protein, can be used as an osteogenic biomaterial. Silk fibroin facilitates osteoblast differentiation into multipotent cells by suppressing the Notch pathway. $ ^{[182]} $ BCP ceramics increased ALP activity and the expression of osteogenesis (OPN/Col/Runx2) in bone marrow-derived stem cells compared with BCP ceramics with Notch signaling inhibitors and control groups (Figure 8C). Histological and histomorphometric analyses demonstrated that the Notch signaling inhibitor delayed bone formation. These findings indicated that the Notch pathway plays an important role in BCP-induced osteogenesis. $ ^{[183]} $", "page_width": 1191, "page_height": 1565, "role": "body_paragraph", "role_confidence": 0.6, "evidence": ["default body_paragraph for text label"], "seed_role": "body_paragraph", "seed_confidence": 0.6, "seed_evidence": ["default body_paragraph for text label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 3, "page": 22, "raw_label": "text", "text": "and skeletal development. Upon cell-cell contact, Notch ligands (Jagged and Delta) interact with Notch receptors (Notch1–4), leading to the cleavage of the Notch intracellular domain. Subsequently, the Notch intracellular domain translocates to the nucleus, and the binding of the Notch intracellular domain to the DNA-binding protein CBF1, Suppressor of Hairless, Lag-1 (CSL) activates the transcription of Notch target genes. Activation of Notch signaling in human bone marrow MSCs stimulates early osteogenic differentiation while suppressing mature osteoblast formation by inhibiting Runx2 activity. Notch2 signaling modulates osteogenic differentiation initiated by BMP and Wnt signaling pathways. Overexpressed Notch intracellular domain inhibits BMP2-mediated Runx2 transcriptional activity and the Wnt-dependent osteogenesis pathway. $ ^{[181]} $ Silk fibroin, a core structural protein, can be used as an osteogenic biomaterial. Silk fibroin facilitates osteoblast differentiation into multipotent cells by suppressing the Notch pathway. $ ^{[182]} $ BCP ceramics increased ALP activity and the expression of osteogenesis (OPN/Col/Runx2) in bone marrow-derived stem cells compared with BCP ceramics with Notch signaling inhibitors and control groups (Figure 8C). Histological and histomorphometric analyses demonstrated that the Notch signaling inhibitor delayed bone formation. These findings indicated that the Notch pathway plays an important role in BCP-induced osteogenesis. $ ^{[183]} $", "bbox": [89, 148, 583, 701], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "and skeletal development. Upon cell-cell contact, Notch ligands (Jagged and Delta) interact with Notch receptors (Notch1–4), leading to the cleavage of the Notch intracellular domain. Subsequently, the Notch intracellular domain translocates to the nucleus, and the binding of the Notch intracellular domain to the DNA-binding protein CBF1, Suppressor of Hairless, Lag-1 (CSL) activates the transcription of Notch target genes. Activation of Notch signaling in human bone marrow MSCs stimulates early osteogenic differentiation while suppressing mature osteoblast formation by inhibiting Runx2 activity. Notch2 signaling modulates osteogenic differentiation initiated by BMP and Wnt signaling pathways. Overexpressed Notch intracellular domain inhibits BMP2-mediated Runx2 transcriptional activity and the Wnt-dependent osteogenesis pathway. $ ^{[181]} $ Silk fibroin, a core structural protein, can be used as an osteogenic biomaterial. Silk fibroin facilitates osteoblast differentiation into multipotent cells by suppressing the Notch pathway. $ ^{[182]} $ BCP ceramics increased ALP activity and the expression of osteogenesis (OPN/Col/Runx2) in bone marrow-derived stem cells compared with BCP ceramics with Notch signaling inhibitors and control groups (Figure 8C). Histological and histomorphometric analyses demonstrated that the Notch signaling inhibitor delayed bone formation. These findings indicated that the Notch pathway plays an important role in BCP-induced osteogenesis. $ ^{[183]} $"}, "layout_signature": {"width": 494, "width_bucket": 500, "height": 553, "left": 89, "top": 148, "right": 583, "bottom": 701, "x_center": 336.0, "x_center_bucket": 325, "y_center": 424.5, "x_ratio": 0.2821, "y_ratio": 0.2712, "width_ratio": 0.4148, "height_ratio": 0.3534, "line_count": 1}, "span_signature": {"font_size": 8.88, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaPro-Regular", "bold": false, "italic": true, "span_count": 319}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_139", "display_cluster_candidate_id": "disp_27_0", "layout_region": "display_zone", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "zone": "body_zone", "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 22, "block_id": 4, "raw_label": "paragraph_title", "raw_order": 2, "bbox": [92, 742, 327, 765], "text": "4.2.4. MAPK Signaling Pathway", "page_width": 1191, "page_height": 1565, "role": "sub_subsection_heading", "role_confidence": 0.85, "evidence": ["paragraph_title label with numbering: 4.2.4. MAPK Signaling Pathway"], "seed_role": "sub_subsection_heading", "seed_confidence": 0.85, "seed_evidence": ["paragraph_title label with numbering: 4.2.4. MAPK Signaling Pathway"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaSansPro-Italic", "flags": 6, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 4, "page": 22, "raw_label": "paragraph_title", "text": "4.2.4. MAPK Signaling Pathway", "bbox": [92, 742, 327, 765], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "heading_numbered", "raw_marker": "4.2.4", "number": "4.2.4", "kind": "heading", "normalized_text": "4.2.4. MAPK Signaling Pathway"}, "layout_signature": {"width": 235, "width_bucket": 225, "height": 23, "left": 92, "top": 742, "right": 327, "bottom": 765, "x_center": 209.5, "x_center_bucket": 200, "y_center": 753.5, "x_ratio": 0.1759, "y_ratio": 0.4815, "width_ratio": 0.1973, "height_ratio": 0.0147, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaSansPro-Italic", "bold": false, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_140", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "zone": "body_zone", "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 22, "block_id": 5, "raw_label": "text", "raw_order": 3, "bbox": [89, 784, 582, 1446], "text": "The mitogen-activated protein kinase (MAPK) family comprises extracellular regulated kinase (ERK), p38, and c-Jun N-terminal kinase (JNK), which are associated with signal transduction in osteoblasts. The MAPK signaling pathway regulates cell proliferation, adhesion, migration, and differentiation in response to external stimuli. Several types of mechanical stimuli, such as compressive force, mechanical stretching, and fluid shear stress, have been reported to enhance osteogenesis through the p38/MAPK pathway. Studies have shown that the MAPK pathway is involved in biomaterial-induced osteogenesis. Akermanite bioceramics ( $ Ca_{2}MgSi_{2}O_{7} $) can promote cell growth, increase ALP activity, and the expression of osteogenic genes and angiogenic factors, while inhibiting the expression of osteoclastogenic factors by activating the ERK, P38, AKT, and STAT3 pathways. $ ^{[184]} $ BGs composed of calcium silicate facilitate osteoblast proliferation and differentiation by activating the MAPK pathway via the release of Si and Ca ions. $ ^{[185]} $ BMDMs cultured on Ti with low surface potential are more inclined polarize towards anti-inflammatory phenotype (M2) in vitro and in vivo. Whole gene expression analysis reveals that inhibition of the PI3K-Akt-mTOR signaling axis is responsible for the immune regulation ability of Ti with low surface potential (Figure 8D). $ ^{[186]} $ Bioactive ions from $ \\beta $-calcium silicate/poly(D, L-lactide-co-glycolide) composite scaffolds facilitate cell proliferation, ALP activity, calcium deposit, and stimulate osteogenic differentiation and angiogenesis through the activation of the MAPK and PI3K/AKT pathways. $ ^{[187]} $ RNA-sequencing suggests that the osteogenic exosomes induce the osteogenic differentiation by using their cargos to activate the PI3K/Akt and MAPK signaling pathways (Figure 8E). $ ^{[101]} $", "page_width": 1191, "page_height": 1565, "role": "body_paragraph", "role_confidence": 0.6, "evidence": ["default body_paragraph for text label"], "seed_role": "body_paragraph", "seed_confidence": 0.6, "seed_evidence": ["default body_paragraph for text label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "STIXMath-Italic", "flags": 6, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 5, "page": 22, "raw_label": "text", "text": "The mitogen-activated protein kinase (MAPK) family comprises extracellular regulated kinase (ERK), p38, and c-Jun N-terminal kinase (JNK), which are associated with signal transduction in osteoblasts. The MAPK signaling pathway regulates cell proliferation, adhesion, migration, and differentiation in response to external stimuli. Several types of mechanical stimuli, such as compressive force, mechanical stretching, and fluid shear stress, have been reported to enhance osteogenesis through the p38/MAPK pathway. Studies have shown that the MAPK pathway is involved in biomaterial-induced osteogenesis. Akermanite bioceramics ( $ Ca_{2}MgSi_{2}O_{7} $) can promote cell growth, increase ALP activity, and the expression of osteogenic genes and angiogenic factors, while inhibiting the expression of osteoclastogenic factors by activating the ERK, P38, AKT, and STAT3 pathways. $ ^{[184]} $ BGs composed of calcium silicate facilitate osteoblast proliferation and differentiation by activating the MAPK pathway via the release of Si and Ca ions. $ ^{[185]} $ BMDMs cultured on Ti with low surface potential are more inclined polarize towards anti-inflammatory phenotype (M2) in vitro and in vivo. Whole gene expression analysis reveals that inhibition of the PI3K-Akt-mTOR signaling axis is responsible for the immune regulation ability of Ti with low surface potential (Figure 8D). $ ^{[186]} $ Bioactive ions from $ \\beta $-calcium silicate/poly(D, L-lactide-co-glycolide) composite scaffolds facilitate cell proliferation, ALP activity, calcium deposit, and stimulate osteogenic differentiation and angiogenesis through the activation of the MAPK and PI3K/AKT pathways. $ ^{[187]} $ RNA-sequencing suggests that the osteogenic exosomes induce the osteogenic differentiation by using their cargos to activate the PI3K/Akt and MAPK signaling pathways (Figure 8E). $ ^{[101]} $", "bbox": [89, 784, 582, 1446], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "The mitogen-activated protein kinase (MAPK) family comprises extracellular regulated kinase (ERK), p38, and c-Jun N-terminal kinase (JNK), which are associated with signal transduction in osteoblasts. The MAPK signaling pathway regulates cell proliferation, adhesion, migration, and differentiation in response to external stimuli. Several types of mechanical stimuli, such as compressive force, mechanical stretching, and fluid shear stress, have been reported to enhance osteogenesis through the p38/MAPK pathway. Studies have shown that the MAPK pathway is involved in biomaterial-induced osteogenesis. Akermanite bioceramics ( $ Ca_{2}MgSi_{2}O_{7} $) can promote cell growth, increase ALP activity, and the expression of osteogenic genes and angiogenic factors, while inhibiting the expression of osteoclastogenic factors by activating the ERK, P38, AKT, and STAT3 pathways. $ ^{[184]} $ BGs composed of calcium silicate facilitate osteoblast proliferation and differentiation by activating the MAPK pathway via the release of Si and Ca ions. $ ^{[185]} $ BMDMs cultured on Ti with low surface potential are more inclined polarize towards anti-inflammatory phenotype (M2) in vitro and in vivo. Whole gene expression analysis reveals that inhibition of the PI3K-Akt-mTOR signaling axis is responsible for the immune regulation ability of Ti with low surface potential (Figure 8D). $ ^{[186]} $ Bioactive ions from $ \\beta $-calcium silicate/poly(D, L-lactide-co-glycolide) composite scaffolds facilitate cell proliferation, ALP activity, calcium deposit, and stimulate osteogenic differentiation and angiogenesis through the activation of the MAPK and PI3K/AKT pathways. $ ^{[187]} $ RNA-sequencing suggests that the osteogenic exosomes induce the osteogenic differentiation by using their cargos to activate the PI3K/Akt and MAPK signaling pathways (Figure 8E). $ ^{[101]} $"}, "layout_signature": {"width": 493, "width_bucket": 500, "height": 662, "left": 89, "top": 784, "right": 582, "bottom": 1446, "x_center": 335.5, "x_center_bucket": 325, "y_center": 1115.0, "x_ratio": 0.2817, "y_ratio": 0.7125, "width_ratio": 0.4139, "height_ratio": 0.423, "line_count": 1}, "span_signature": {"font_size": 8.8, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaPro-Regular", "bold": false, "italic": true, "span_count": 331}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_139", "display_cluster_candidate_id": "disp_27_0", "layout_region": "display_zone", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "zone": "body_zone", "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 22, "block_id": 6, "raw_label": "paragraph_title", "raw_order": 4, "bbox": [602, 148, 1001, 172], "text": "4.2.5. Other Osteogenesis-Relevant Signaling Pathways", "page_width": 1191, "page_height": 1565, "role": "sub_subsection_heading", "role_confidence": 0.85, "evidence": ["paragraph_title label with numbering: 4.2.5. Other Osteogenesis-Relevant Signaling Pathways"], "seed_role": "sub_subsection_heading", "seed_confidence": 0.85, "seed_evidence": ["paragraph_title label with numbering: 4.2.5. Other Osteogenesis-Relevant Signaling Pathways"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaSansPro-Italic", "flags": 6, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 6, "page": 22, "raw_label": "paragraph_title", "text": "4.2.5. Other Osteogenesis-Relevant Signaling Pathways", "bbox": [602, 148, 1001, 172], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "heading_numbered", "raw_marker": "4.2.5", "number": "4.2.5", "kind": "heading", "normalized_text": "4.2.5. Other Osteogenesis-Relevant Signaling Pathways"}, "layout_signature": {"width": 399, "width_bucket": 400, "height": 24, "left": 602, "top": 148, "right": 1001, "bottom": 172, "x_center": 801.5, "x_center_bucket": 800, "y_center": 160.0, "x_ratio": 0.673, "y_ratio": 0.1022, "width_ratio": 0.335, "height_ratio": 0.0153, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaSansPro-Italic", "bold": false, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_140", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "zone": "body_zone", "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 22, "block_id": 7, "raw_label": "text", "raw_order": 5, "bbox": [599, 192, 1093, 524], "text": "In addition to the aforementioned pathways, bone development and homeostasis involve several other pathways that play an indispensable role in the osteogenic differentiation of undifferentiated and osteoprogenitor cells. For example, YAP/TAZ signaling, integrin signaling, calcium and phosphate signaling. Fast “dynamic bridges” to construct viscoelastic gelatin methacryloyl (GelMA)-based hydrogels, the viscous dissipation of hydrogels activated YAP by stabilizing integrin $ \\beta_1 $, and further promoted nuclear translocation of smad2/3 and $ \\beta $-catenin to enhance chondrogenesis and osteogenesis (Figure 8F). $ ^{[188]} $ NF- $ \\kappa $B signaling, and Hedgehog signaling have been proven to regulate osteogenic differentiation in stem cells. Therefore, elucidating the mechanisms through which biomaterial properties modulate cellular responses and molecular events during bone regeneration is critical for designing superior bone biomaterials.", "page_width": 1191, "page_height": 1565, "role": "body_paragraph", "role_confidence": 0.6, "evidence": ["default body_paragraph for text label"], "seed_role": "body_paragraph", "seed_confidence": 0.6, "seed_evidence": ["default body_paragraph for text label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "STIXMath-Italic", "flags": 6, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "STIXMath-Italic", "flags": 6, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "STIXMath-Italic", "flags": 6, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 255, "dir": [1.0, 0.0], "wmode": 0}, {"size": 5.97760009765625, "font": "ScalaPro-Regular", "flags": 5, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 5, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "STIXMath-Italic", "flags": 6, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 7, "page": 22, "raw_label": "text", "text": "In addition to the aforementioned pathways, bone development and homeostasis involve several other pathways that play an indispensable role in the osteogenic differentiation of undifferentiated and osteoprogenitor cells. For example, YAP/TAZ signaling, integrin signaling, calcium and phosphate signaling. Fast “dynamic bridges” to construct viscoelastic gelatin methacryloyl (GelMA)-based hydrogels, the viscous dissipation of hydrogels activated YAP by stabilizing integrin $ \\beta_1 $, and further promoted nuclear translocation of smad2/3 and $ \\beta $-catenin to enhance chondrogenesis and osteogenesis (Figure 8F). $ ^{[188]} $ NF- $ \\kappa $B signaling, and Hedgehog signaling have been proven to regulate osteogenic differentiation in stem cells. Therefore, elucidating the mechanisms through which biomaterial properties modulate cellular responses and molecular events during bone regeneration is critical for designing superior bone biomaterials.", "bbox": [599, 192, 1093, 524], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "In addition to the aforementioned pathways, bone development and homeostasis involve several other pathways that play an indispensable role in the osteogenic differentiation of undifferentiated and osteoprogenitor cells. For example, YAP/TAZ signaling, integrin signaling, calcium and phosphate signaling. Fast “dynamic bridges” to construct viscoelastic gelatin methacryloyl (GelMA)-based hydrogels, the viscous dissipation of hydrogels activated YAP by stabilizing integrin $ \\beta_1 $, and further promoted nuclear translocation of smad2/3 and $ \\beta $-catenin to enhance chondrogenesis and osteogenesis (Figure 8F). $ ^{[188]} $ NF- $ \\kappa $B signaling, and Hedgehog signaling have been proven to regulate osteogenic differentiation in stem cells. Therefore, elucidating the mechanisms through which biomaterial properties modulate cellular responses and molecular events during bone regeneration is critical for designing superior bone biomaterials."}, "layout_signature": {"width": 494, "width_bucket": 500, "height": 332, "left": 599, "top": 192, "right": 1093, "bottom": 524, "x_center": 846.0, "x_center_bucket": 850, "y_center": 358.0, "x_ratio": 0.7103, "y_ratio": 0.2288, "width_ratio": 0.4148, "height_ratio": 0.2121, "line_count": 1}, "span_signature": {"font_size": 8.89, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaPro-Regular", "bold": false, "italic": true, "span_count": 118}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_139", "display_cluster_candidate_id": "disp_27_0", "layout_region": "display_zone", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "zone": "body_zone", "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 22, "block_id": 8, "raw_label": "paragraph_title", "raw_order": 6, "bbox": [602, 548, 873, 574], "text": "5. Conclusions and Outlook", "page_width": 1191, "page_height": 1565, "role": "section_heading", "role_confidence": 0.85, "evidence": ["paragraph_title label with numbering: 5. Conclusions and Outlook"], "seed_role": "section_heading", "seed_confidence": 0.85, "seed_evidence": ["paragraph_title label with numbering: 5. Conclusions and Outlook"], "span_metadata": [{"size": 11.456999778747559, "font": "ScalaSansPro-Bold", "flags": 20, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 8, "page": 22, "raw_label": "paragraph_title", "text": "5. Conclusions and Outlook", "bbox": [602, 548, 873, 574], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "heading_numbered", "raw_marker": "5", "number": "5", "kind": "heading", "normalized_text": "5. Conclusions and Outlook"}, "layout_signature": {"width": 271, "width_bucket": 275, "height": 26, "left": 602, "top": 548, "right": 873, "bottom": 574, "x_center": 737.5, "x_center_bucket": 750, "y_center": 561.0, "x_ratio": 0.6192, "y_ratio": 0.3585, "width_ratio": 0.2275, "height_ratio": 0.0166, "line_count": 1}, "span_signature": {"font_size": 11.46, "font_size_median": 11.46, "font_size_bucket": 11.5, "font_family_norm": "ScalaSansPro-Bold", "bold": true, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "style_family": "heading_like", "style_family_authority": "heading_typography", "reading_band_id": "band_140", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "zone": "body_zone", "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "accepted_heading", "role_evidence": ["heading verified by heading artifact"]}
+{"paper_id": "2HEUD5P9", "page": 22, "block_id": 9, "raw_label": "text", "raw_order": 7, "bbox": [600, 588, 1093, 961], "text": "Herein, we summarized several biomaterials with unique biofunctions, bioactive compounds, 3D bioprinting techniques, and physical stimuli-responsive strategies for bone repair and regeneration. Among the materials, metals still need more research regarding their biocompatibility, biodegradability, and corrosion properties in vivo, as well as clinical evaluations, while ceramic biomaterials predominantly applied to fabricate bone scaffolds need to be combined with metals or polymers to obtain a suitable degradation rate and mechanical strength. Natural polymers have drawbacks such as low mechanical strength, high production cost, batch inconsistency, and immunogenicity, while synthetic polymers have limitations such as a lack of bioactivity, slow degradation, and harmful degradation products. These challenges have motivated biomaterial designers to develop new composites. Composites can enhance bioactivity and integrate the desirable properties of different materials to fully mimic the characteristics of natural bone.", "page_width": 1191, "page_height": 1565, "role": "body_paragraph", "role_confidence": 0.6, "evidence": ["default body_paragraph for text label"], "seed_role": "body_paragraph", "seed_confidence": 0.6, "seed_evidence": ["default body_paragraph for text label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 9, "page": 22, "raw_label": "text", "text": "Herein, we summarized several biomaterials with unique biofunctions, bioactive compounds, 3D bioprinting techniques, and physical stimuli-responsive strategies for bone repair and regeneration. Among the materials, metals still need more research regarding their biocompatibility, biodegradability, and corrosion properties in vivo, as well as clinical evaluations, while ceramic biomaterials predominantly applied to fabricate bone scaffolds need to be combined with metals or polymers to obtain a suitable degradation rate and mechanical strength. Natural polymers have drawbacks such as low mechanical strength, high production cost, batch inconsistency, and immunogenicity, while synthetic polymers have limitations such as a lack of bioactivity, slow degradation, and harmful degradation products. These challenges have motivated biomaterial designers to develop new composites. Composites can enhance bioactivity and integrate the desirable properties of different materials to fully mimic the characteristics of natural bone.", "bbox": [600, 588, 1093, 961], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "Herein, we summarized several biomaterials with unique biofunctions, bioactive compounds, 3D bioprinting techniques, and physical stimuli-responsive strategies for bone repair and regeneration. Among the materials, metals still need more research regarding their biocompatibility, biodegradability, and corrosion properties in vivo, as well as clinical evaluations, while ceramic biomaterials predominantly applied to fabricate bone scaffolds need to be combined with metals or polymers to obtain a suitable degradation rate and mechanical strength. Natural polymers have drawbacks such as low mechanical strength, high production cost, batch inconsistency, and immunogenicity, while synthetic polymers have limitations such as a lack of bioactivity, slow degradation, and harmful degradation products. These challenges have motivated biomaterial designers to develop new composites. Composites can enhance bioactivity and integrate the desirable properties of different materials to fully mimic the characteristics of natural bone."}, "layout_signature": {"width": 493, "width_bucket": 500, "height": 373, "left": 600, "top": 588, "right": 1093, "bottom": 961, "x_center": 846.5, "x_center_bucket": 850, "y_center": 774.5, "x_ratio": 0.7107, "y_ratio": 0.4949, "width_ratio": 0.4139, "height_ratio": 0.2383, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaPro-Regular", "bold": false, "italic": true, "span_count": 147}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_138", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "zone": "body_zone", "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 22, "block_id": 10, "raw_label": "text", "raw_order": 8, "bbox": [598, 961, 1094, 1446], "text": "3D printing technology is a novel strategy in precision medicine that can produce bone implants using multiple materials based on digital models. With advances in 3D printing technology, novel composite materials with superior properties are rapidly emerging and being applied in clinical trials. 3D printing technology has great potential for personalized and accurate bone repair. Moreover, 3D bioprinting can precisely control the microstructure of the scaffolds. 3D printing can be used to customize scaffolds according to individual needs and to provide a suitable environment for cell adhesion and bone conduction. With the interdisciplinary development of 3D printing technology, 3D-printed bone scaffolds are expected to have excellent application prospects in bone repair and regeneration. In addition to 3D printing technology, physical stimuli-responsive strategies have received extensive attention. Physical stimuli-responsive biomaterials can use external triggers, such as light irradiation, electric and magnetic fields, ultrasound, or other mechanical stimuli, to achieve better therapeutic and regenerative outcomes. After eliminating severe infection, residual tumor tissue, or other bone diseases in a short and effective manner, a therapeutic biomaterial should promote cell attachment. Physical stimuli-responsive materials can release bioactive or", "page_width": 1191, "page_height": 1565, "role": "body_paragraph", "role_confidence": 0.6, "evidence": ["default body_paragraph for text label"], "seed_role": "body_paragraph", "seed_confidence": 0.6, "seed_evidence": ["default body_paragraph for text label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 10, "page": 22, "raw_label": "text", "text": "3D printing technology is a novel strategy in precision medicine that can produce bone implants using multiple materials based on digital models. With advances in 3D printing technology, novel composite materials with superior properties are rapidly emerging and being applied in clinical trials. 3D printing technology has great potential for personalized and accurate bone repair. Moreover, 3D bioprinting can precisely control the microstructure of the scaffolds. 3D printing can be used to customize scaffolds according to individual needs and to provide a suitable environment for cell adhesion and bone conduction. With the interdisciplinary development of 3D printing technology, 3D-printed bone scaffolds are expected to have excellent application prospects in bone repair and regeneration. In addition to 3D printing technology, physical stimuli-responsive strategies have received extensive attention. Physical stimuli-responsive biomaterials can use external triggers, such as light irradiation, electric and magnetic fields, ultrasound, or other mechanical stimuli, to achieve better therapeutic and regenerative outcomes. After eliminating severe infection, residual tumor tissue, or other bone diseases in a short and effective manner, a therapeutic biomaterial should promote cell attachment. Physical stimuli-responsive materials can release bioactive or", "bbox": [598, 961, 1094, 1446], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "3D printing technology is a novel strategy in precision medicine that can produce bone implants using multiple materials based on digital models. With advances in 3D printing technology, novel composite materials with superior properties are rapidly emerging and being applied in clinical trials. 3D printing technology has great potential for personalized and accurate bone repair. Moreover, 3D bioprinting can precisely control the microstructure of the scaffolds. 3D printing can be used to customize scaffolds according to individual needs and to provide a suitable environment for cell adhesion and bone conduction. With the interdisciplinary development of 3D printing technology, 3D-printed bone scaffolds are expected to have excellent application prospects in bone repair and regeneration. In addition to 3D printing technology, physical stimuli-responsive strategies have received extensive attention. Physical stimuli-responsive biomaterials can use external triggers, such as light irradiation, electric and magnetic fields, ultrasound, or other mechanical stimuli, to achieve better therapeutic and regenerative outcomes. After eliminating severe infection, residual tumor tissue, or other bone diseases in a short and effective manner, a therapeutic biomaterial should promote cell attachment. Physical stimuli-responsive materials can release bioactive or"}, "layout_signature": {"width": 496, "width_bucket": 500, "height": 485, "left": 598, "top": 961, "right": 1094, "bottom": 1446, "x_center": 846.0, "x_center_bucket": 850, "y_center": 1203.5, "x_ratio": 0.7103, "y_ratio": 0.769, "width_ratio": 0.4165, "height_ratio": 0.3099, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaPro-Regular", "bold": false, "italic": true, "span_count": 278}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_141", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "hard", "boundary_after": "none", "bridge_eligible": false, "zone": "body_zone", "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 22, "block_id": 11, "raw_label": "footer", "raw_order": null, "bbox": [93, 1487, 283, 1505], "text": "Small Methods 2024, 8, 2301283", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["footer label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["footer label"], "span_metadata": [{"size": 6.973800182342529, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 11, "page": 22, "raw_label": "footer", "text": "Small Methods 2024, 8, 2301283", "bbox": [93, 1487, 283, 1505], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "Small Methods 2024, 8, 2301283"}, "layout_signature": {"width": 190, "width_bucket": 200, "height": 18, "left": 93, "top": 1487, "right": 283, "bottom": 1505, "x_center": 188.0, "x_center_bucket": 200, "y_center": 1496.0, "x_ratio": 0.1579, "y_ratio": 0.9559, "width_ratio": 0.1595, "height_ratio": 0.0115, "line_count": 1}, "span_signature": {"font_size": 6.97, "font_size_median": 6.97, "font_size_bucket": 7.0, "font_family_norm": "ScalaSansPro-Italic", "bold": true, "italic": true, "span_count": 5}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_142", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 22, "block_id": 12, "raw_label": "footer", "raw_order": null, "bbox": [520, 1484, 663, 1507], "text": "2301283 (22 of 27)", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.9, "evidence": ["footer label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["footer label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaSansPro-Bold", "flags": 20, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 12, "page": 22, "raw_label": "footer", "text": "2301283 (22 of 27)", "bbox": [520, 1484, 663, 1507], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_dot", "raw_marker": "2301283", "number": 2301283, "kind": "reference", "normalized_text": "2301283 (22 of 27)"}, "layout_signature": {"width": 143, "width_bucket": 150, "height": 23, "left": 520, "top": 1484, "right": 663, "bottom": 1507, "x_center": 591.5, "x_center_bucket": 600, "y_center": 1495.5, "x_ratio": 0.4966, "y_ratio": 0.9556, "width_ratio": 0.1201, "height_ratio": 0.0147, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaSansPro-Bold", "bold": true, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_family_anchor", "reading_band_id": "band_142", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 22, "block_id": 13, "raw_label": "footer", "raw_order": null, "bbox": [931, 1487, 1090, 1506], "text": "© 2024 Wiley-VCH GmbH", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["footer label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["footer label"], "span_metadata": [{"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 13, "page": 22, "raw_label": "footer", "text": "© 2024 Wiley-VCH GmbH", "bbox": [931, 1487, 1090, 1506], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "© 2024 Wiley-VCH GmbH"}, "layout_signature": {"width": 159, "width_bucket": 150, "height": 19, "left": 931, "top": 1487, "right": 1090, "bottom": 1506, "x_center": 1010.5, "x_center_bucket": 1000, "y_center": 1496.5, "x_ratio": 0.8484, "y_ratio": 0.9562, "width_ratio": 0.1335, "height_ratio": 0.0121, "line_count": 1}, "span_signature": {"font_size": 6.97, "font_size_median": 6.97, "font_size_bucket": 7.0, "font_family_norm": "ScalaSansPro-Regular", "bold": false, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_136", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 22, "block_id": 14, "raw_label": "aside_text", "raw_order": null, "bbox": [1154, 30, 1171, 1534], "text": "23699608, 2024, 8, Downloaded from https://onlinelibrary.wiley.com/doi/10.1002/smkt.202301283 by Shandong University Library, Wiley Online Library on [18/02/2026]. See the Terms and Conditions (https://onlinelibrary.wiley.com/terms-and-conditions) on Wiley Online Library for rules of use; OA articles are governed by the applicable Creative Commons License.", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.95, "evidence": ["margin-band narrow/tall geometry; treated as noise"], "seed_role": "noise", "seed_confidence": 0.95, "seed_evidence": ["margin-band narrow/tall geometry; treated as noise"], "span_metadata": [{"size": 5.03000020980835, "font": "Times-Roman", "flags": 4, "color": 0, "dir": [0.0, 1.0], "wmode": 0}], "raw_observation": {"block_id": 14, "page": 22, "raw_label": "aside_text", "text": "23699608, 2024, 8, Downloaded from https://onlinelibrary.wiley.com/doi/10.1002/smkt.202301283 by Shandong University Library, Wiley Online Library on [18/02/2026]. See the Terms and Conditions (https://onlinelibrary.wiley.com/terms-and-conditions) on Wiley Online Library for rules of use; OA articles are governed by the applicable Creative Commons License.", "bbox": [1154, 30, 1171, 1534], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "23699608, 2024, 8, Downloaded from https://onlinelibrary.wiley.com/doi/10.1002/smkt.202301283 by Shandong University Library, Wiley Online Library on [18/02/2026]. See the Terms and Conditions (https://onlinelibrary.wiley.com/terms-and-conditions) on Wiley Online Library for rules of use; OA articles are governed by the applicable Creative Commons License."}, "layout_signature": {"width": 17, "width_bucket": 25, "height": 1504, "left": 1154, "top": 30, "right": 1171, "bottom": 1534, "x_center": 1162.5, "x_center_bucket": 1150, "y_center": 782.0, "x_ratio": 0.9761, "y_ratio": 0.4997, "width_ratio": 0.0143, "height_ratio": 0.961, "line_count": 1}, "span_signature": {"font_size": 5.03, "font_size_median": 5.03, "font_size_bucket": 5.0, "font_family_norm": "Times-Roman", "bold": false, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_family_anchor", "reading_band_id": "band_136", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 23, "block_id": 0, "raw_label": "header", "raw_order": null, "bbox": [98, 46, 345, 117], "text": "ADVANCED\nSCIENCE NEWS\nwww.advancedsciencenews.com", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["header label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["header label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaSansPro-Bold", "flags": 20, "color": 255, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 0, "page": 23, "raw_label": "header", "text": "ADVANCED\nSCIENCE NEWS\nwww.advancedsciencenews.com", "bbox": [98, 46, 345, 117], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "ADVANCED\nSCIENCE NEWS\nwww.advancedsciencenews.com"}, "layout_signature": {"width": 247, "width_bucket": 250, "height": 71, "left": 98, "top": 46, "right": 345, "bottom": 117, "x_center": 221.5, "x_center_bucket": 225, "y_center": 81.5, "x_ratio": 0.186, "y_ratio": 0.0521, "width_ratio": 0.2074, "height_ratio": 0.0454, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaSansPro-Bold", "bold": true, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 23, "block_id": 1, "raw_label": "header_image", "raw_order": null, "bbox": [1003, 36, 1095, 95], "text": "", "page_width": 1191, "page_height": 1565, "role": "unknown_structural", "role_confidence": 0.2, "evidence": ["unrecognized label 'header_image'"], "seed_role": "unknown_structural", "seed_confidence": 0.2, "seed_evidence": ["unrecognized label 'header_image'"], "span_metadata": null, "raw_observation": {"block_id": 1, "page": 23, "raw_label": "header_image", "text": "", "bbox": [1003, 36, 1095, 95], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "empty", "raw_marker": null, "number": null, "kind": null, "normalized_text": ""}, "layout_signature": {"width": 92, "width_bucket": 100, "height": 59, "left": 1003, "top": 36, "right": 1095, "bottom": 95, "x_center": 1049.0, "x_center_bucket": 1050, "y_center": 65.5, "x_ratio": 0.8808, "y_ratio": 0.0419, "width_ratio": 0.0772, "height_ratio": 0.0377, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": true, "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_142", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["non-structural role accepted"]}
+{"paper_id": "2HEUD5P9", "page": 23, "block_id": 2, "raw_label": "header", "raw_order": null, "bbox": [903, 98, 1096, 116], "text": "www.small-methods.com", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["header label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["header label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaSansPro-Bold", "flags": 20, "color": 255, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 2, "page": 23, "raw_label": "header", "text": "www.small-methods.com", "bbox": [903, 98, 1096, 116], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "www.small-methods.com"}, "layout_signature": {"width": 193, "width_bucket": 200, "height": 18, "left": 903, "top": 98, "right": 1096, "bottom": 116, "x_center": 999.5, "x_center_bucket": 1000, "y_center": 107.0, "x_ratio": 0.8392, "y_ratio": 0.0684, "width_ratio": 0.162, "height_ratio": 0.0115, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaSansPro-Bold", "bold": true, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_142", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 23, "block_id": 3, "raw_label": "text", "raw_order": 1, "bbox": [96, 149, 587, 236], "text": "osteogenic substances to stimulate cell growth and differentiation, ultimately improving bone regeneration. These advanced strategies will play crucial roles in precise and efficient bone-tissue repair and regeneration.", "page_width": 1191, "page_height": 1565, "role": "body_paragraph", "role_confidence": 0.6, "evidence": ["default body_paragraph for text label"], "seed_role": "body_paragraph", "seed_confidence": 0.6, "seed_evidence": ["default body_paragraph for text label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 3, "page": 23, "raw_label": "text", "text": "osteogenic substances to stimulate cell growth and differentiation, ultimately improving bone regeneration. These advanced strategies will play crucial roles in precise and efficient bone-tissue repair and regeneration.", "bbox": [96, 149, 587, 236], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "osteogenic substances to stimulate cell growth and differentiation, ultimately improving bone regeneration. These advanced strategies will play crucial roles in precise and efficient bone-tissue repair and regeneration."}, "layout_signature": {"width": 491, "width_bucket": 500, "height": 87, "left": 96, "top": 149, "right": 587, "bottom": 236, "x_center": 341.5, "x_center_bucket": 350, "y_center": 192.5, "x_ratio": 0.2867, "y_ratio": 0.123, "width_ratio": 0.4123, "height_ratio": 0.0556, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaPro-Regular", "bold": false, "italic": true, "span_count": 48}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_139", "display_cluster_candidate_id": "disp_27_0", "layout_region": "display_zone", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 23, "block_id": 4, "raw_label": "text", "raw_order": 2, "bbox": [96, 237, 587, 479], "text": "Despite the promising results presented herein, the literature primarily focuses on the development of scaffolds using advanced biomaterials, but lacks sufficient researches on the use of biomaterial-cell systems for bone repair and regeneration. Additionally, detailed protocols are required for the extraction, culturing, and seeding of stem cells on scaffolds to create tissues comparable to natural bone in terms of quality and stability. The application of biomaterials for bone regeneration still requires a thorough understanding of the complex molecular mechanisms involved in osteogenesis induction and faces several challenges that need to be addressed in future investigations.", "page_width": 1191, "page_height": 1565, "role": "body_paragraph", "role_confidence": 0.6, "evidence": ["default body_paragraph for text label"], "seed_role": "body_paragraph", "seed_confidence": 0.6, "seed_evidence": ["default body_paragraph for text label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 4, "page": 23, "raw_label": "text", "text": "Despite the promising results presented herein, the literature primarily focuses on the development of scaffolds using advanced biomaterials, but lacks sufficient researches on the use of biomaterial-cell systems for bone repair and regeneration. Additionally, detailed protocols are required for the extraction, culturing, and seeding of stem cells on scaffolds to create tissues comparable to natural bone in terms of quality and stability. The application of biomaterials for bone regeneration still requires a thorough understanding of the complex molecular mechanisms involved in osteogenesis induction and faces several challenges that need to be addressed in future investigations.", "bbox": [96, 237, 587, 479], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "Despite the promising results presented herein, the literature primarily focuses on the development of scaffolds using advanced biomaterials, but lacks sufficient researches on the use of biomaterial-cell systems for bone repair and regeneration. Additionally, detailed protocols are required for the extraction, culturing, and seeding of stem cells on scaffolds to create tissues comparable to natural bone in terms of quality and stability. The application of biomaterials for bone regeneration still requires a thorough understanding of the complex molecular mechanisms involved in osteogenesis induction and faces several challenges that need to be addressed in future investigations."}, "layout_signature": {"width": 491, "width_bucket": 500, "height": 242, "left": 96, "top": 237, "right": 587, "bottom": 479, "x_center": 341.5, "x_center_bucket": 350, "y_center": 358.0, "x_ratio": 0.2867, "y_ratio": 0.2288, "width_ratio": 0.4123, "height_ratio": 0.1546, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaPro-Regular", "bold": false, "italic": true, "span_count": 75}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_140", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 23, "block_id": 5, "raw_label": "paragraph_title", "raw_order": 3, "bbox": [97, 524, 289, 549], "text": "Acknowledgements", "page_width": 1191, "page_height": 1565, "role": "backmatter_heading", "role_confidence": 0.65, "evidence": ["backmatter heading candidate: Acknowledgements"], "seed_role": "backmatter_heading_candidate", "seed_confidence": 0.65, "seed_evidence": ["backmatter heading candidate: Acknowledgements"], "span_metadata": [{"size": 11.456999778747559, "font": "ScalaSansPro-Bold", "flags": 20, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 5, "page": 23, "raw_label": "paragraph_title", "text": "Acknowledgements", "bbox": [97, 524, 289, 549], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "short_fragment", "raw_marker": "Acknowledgements", "number": null, "kind": "short_fragment", "normalized_text": "Acknowledgements"}, "layout_signature": {"width": 192, "width_bucket": 200, "height": 25, "left": 97, "top": 524, "right": 289, "bottom": 549, "x_center": 193.0, "x_center_bucket": 200, "y_center": 536.5, "x_ratio": 0.162, "y_ratio": 0.3428, "width_ratio": 0.1612, "height_ratio": 0.016, "line_count": 1}, "span_signature": {"font_size": 11.46, "font_size_median": 11.46, "font_size_bucket": 11.5, "font_family_norm": "ScalaSansPro-Bold", "bold": true, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "style_family": "heading_like", "style_family_authority": "heading_typography", "reading_band_id": "band_139", "display_cluster_candidate_id": "disp_27_0", "layout_region": "display_zone", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 23, "block_id": 6, "raw_label": "text", "raw_order": 4, "bbox": [97, 560, 587, 715], "text": "Y.B. and Z.W. contributed equally to this work. This work was financially supported by the National Science Fund for Distinguished Young Scholars (grant no. 82225027), the National Key Research and Development Program (grant no. 2021YFA1101301), the National Natural Science Foundation of China (grant nos. 82202702, 82202351, 82271419, 82001308, 82271418, and 82172116), the Program for the Development of Science and Technology Committee of Shanghai (grant no. PKJ2022-Y22), and the China Postdoctoral Science Foundation (grant no. 2023M74264).", "page_width": 1191, "page_height": 1565, "role": "backmatter_body", "role_confidence": 0.6, "evidence": ["default body_paragraph for text label"], "seed_role": "body_paragraph", "seed_confidence": 0.6, "seed_evidence": ["default body_paragraph for text label"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 6, "page": 23, "raw_label": "text", "text": "Y.B. and Z.W. contributed equally to this work. This work was financially supported by the National Science Fund for Distinguished Young Scholars (grant no. 82225027), the National Key Research and Development Program (grant no. 2021YFA1101301), the National Natural Science Foundation of China (grant nos. 82202702, 82202351, 82271419, 82001308, 82271418, and 82172116), the Program for the Development of Science and Technology Committee of Shanghai (grant no. PKJ2022-Y22), and the China Postdoctoral Science Foundation (grant no. 2023M74264).", "bbox": [97, 560, 587, 715], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "Y.B. and Z.W. contributed equally to this work. This work was financially supported by the National Science Fund for Distinguished Young Scholars (grant no. 82225027), the National Key Research and Development Program (grant no. 2021YFA1101301), the National Natural Science Foundation of China (grant nos. 82202702, 82202351, 82271419, 82001308, 82271418, and 82172116), the Program for the Development of Science and Technology Committee of Shanghai (grant no. PKJ2022-Y22), and the China Postdoctoral Science Foundation (grant no. 2023M74264)."}, "layout_signature": {"width": 490, "width_bucket": 500, "height": 155, "left": 97, "top": 560, "right": 587, "bottom": 715, "x_center": 342.0, "x_center_bucket": 350, "y_center": 637.5, "x_ratio": 0.2872, "y_ratio": 0.4073, "width_ratio": 0.4114, "height_ratio": 0.099, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": false, "italic": true, "span_count": 98}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_140", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 23, "block_id": 7, "raw_label": "paragraph_title", "raw_order": 5, "bbox": [97, 759, 281, 784], "text": "Conflict of Interest", "page_width": 1191, "page_height": 1565, "role": "unknown_structural", "role_confidence": 0.5, "evidence": ["backmatter heading candidate: Conflict of Interest"], "seed_role": "backmatter_heading_candidate", "seed_confidence": 0.65, "seed_evidence": ["backmatter heading candidate: Conflict of Interest"], "span_metadata": [{"size": 11.456999778747559, "font": "ScalaSansPro-Bold", "flags": 20, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 7, "page": 23, "raw_label": "paragraph_title", "text": "Conflict of Interest", "bbox": [97, 759, 281, 784], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "Conflict of Interest"}, "layout_signature": {"width": 184, "width_bucket": 175, "height": 25, "left": 97, "top": 759, "right": 281, "bottom": 784, "x_center": 189.0, "x_center_bucket": 200, "y_center": 771.5, "x_ratio": 0.1587, "y_ratio": 0.493, "width_ratio": 0.1545, "height_ratio": 0.016, "line_count": 1}, "span_signature": {"font_size": 11.46, "font_size_median": 11.46, "font_size_bucket": 11.5, "font_family_norm": "ScalaSansPro-Bold", "bold": true, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": true, "style_family": "support_like", "style_family_authority": "editorial_phrase", "reading_band_id": "band_139", "display_cluster_candidate_id": "disp_27_0", "layout_region": "display_zone", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "HOLD", "role_source": "structural_gate", "role_evidence": ["section_heading lacks heading artifact evidence"], "role_candidate": "backmatter_heading_candidate"}
+{"paper_id": "2HEUD5P9", "page": 23, "block_id": 8, "raw_label": "text", "raw_order": 6, "bbox": [97, 797, 382, 817], "text": "The authors declare no conflict of interest.", "page_width": 1191, "page_height": 1565, "role": "frontmatter_noise", "role_confidence": 0.88, "evidence": ["default body_paragraph for text label", "late role resolution: editorial phrase cross-validates non-body classification", "zone=body_zone", "style_family=support_like"], "seed_role": "body_paragraph", "seed_confidence": 0.6, "seed_evidence": ["default body_paragraph for text label"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 8, "page": 23, "raw_label": "text", "text": "The authors declare no conflict of interest.", "bbox": [97, 797, 382, 817], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "The authors declare no conflict of interest."}, "layout_signature": {"width": 285, "width_bucket": 275, "height": 20, "left": 97, "top": 797, "right": 382, "bottom": 817, "x_center": 239.5, "x_center_bucket": 250, "y_center": 807.0, "x_ratio": 0.2011, "y_ratio": 0.5157, "width_ratio": 0.2393, "height_ratio": 0.0128, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": false, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "support_like", "style_family_authority": "editorial_phrase", "reading_band_id": "band_140", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 23, "block_id": 9, "raw_label": "paragraph_title", "raw_order": 7, "bbox": [98, 863, 196, 888], "text": "Keywords", "page_width": 1191, "page_height": 1565, "role": "sub_subsection_heading", "role_confidence": 0.6, "evidence": ["unnumbered paragraph_title, inferred level sub_subsection_heading: Keywords"], "seed_role": "sub_subsection_heading", "seed_confidence": 0.6, "seed_evidence": ["unnumbered paragraph_title, inferred level sub_subsection_heading: Keywords"], "span_metadata": [{"size": 11.456999778747559, "font": "ScalaSansPro-Bold", "flags": 20, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 9, "page": 23, "raw_label": "paragraph_title", "text": "Keywords", "bbox": [98, 863, 196, 888], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "short_fragment", "raw_marker": "Keywords", "number": null, "kind": "short_fragment", "normalized_text": "Keywords"}, "layout_signature": {"width": 98, "width_bucket": 100, "height": 25, "left": 98, "top": 863, "right": 196, "bottom": 888, "x_center": 147.0, "x_center_bucket": 150, "y_center": 875.5, "x_ratio": 0.1234, "y_ratio": 0.5594, "width_ratio": 0.0823, "height_ratio": 0.016, "line_count": 1}, "span_signature": {"font_size": 11.46, "font_size_median": 11.46, "font_size_bucket": 11.5, "font_family_norm": "ScalaSansPro-Bold", "bold": true, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "body_zone", "style_family": "heading_like", "style_family_authority": "heading_typography", "reading_band_id": "band_138", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 23, "block_id": 10, "raw_label": "text", "raw_order": 8, "bbox": [97, 900, 586, 940], "text": "advanced techniques, bioactive materials, bone regeneration, molecular mechanism, stem cells", "page_width": 1191, "page_height": 1565, "role": "backmatter_body", "role_confidence": 0.6, "evidence": ["default body_paragraph for text label"], "seed_role": "body_paragraph", "seed_confidence": 0.6, "seed_evidence": ["default body_paragraph for text label"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 10, "page": 23, "raw_label": "text", "text": "advanced techniques, bioactive materials, bone regeneration, molecular mechanism, stem cells", "bbox": [97, 900, 586, 940], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "advanced techniques, bioactive materials, bone regeneration, molecular mechanism, stem cells"}, "layout_signature": {"width": 489, "width_bucket": 500, "height": 40, "left": 97, "top": 900, "right": 586, "bottom": 940, "x_center": 341.5, "x_center_bucket": 350, "y_center": 920.0, "x_ratio": 0.2867, "y_ratio": 0.5879, "width_ratio": 0.4106, "height_ratio": 0.0256, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": false, "italic": true, "span_count": 14}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_141", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "hard", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 23, "block_id": 11, "raw_label": "text", "raw_order": 9, "bbox": [360, 963, 586, 1020], "text": "Received: September 22, 2023 \nRevised: November 4, 2023 \nPublished online: March 21, 2024", "page_width": 1191, "page_height": 1565, "role": "frontmatter_noise", "role_confidence": 0.88, "evidence": ["default body_paragraph for text label", "late role resolution: editorial phrase cross-validates non-body classification", "zone=body_zone", "style_family=support_like"], "seed_role": "body_paragraph", "seed_confidence": 0.6, "seed_evidence": ["default body_paragraph for text label"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 11, "page": 23, "raw_label": "text", "text": "Received: September 22, 2023 \nRevised: November 4, 2023 \nPublished online: March 21, 2024", "bbox": [360, 963, 586, 1020], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "Received: September 22, 2023 \nRevised: November 4, 2023 \nPublished online: March 21, 2024"}, "layout_signature": {"width": 226, "width_bucket": 225, "height": 57, "left": 360, "top": 963, "right": 586, "bottom": 1020, "x_center": 473.0, "x_center_bucket": 475, "y_center": 991.5, "x_ratio": 0.3971, "y_ratio": 0.6335, "width_ratio": 0.1898, "height_ratio": 0.0364, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": false, "italic": true, "span_count": 3}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "support_like", "style_family_authority": "editorial_phrase", "reading_band_id": "band_142", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 23, "block_id": 12, "raw_label": "reference_content", "raw_order": 10, "bbox": [115, 1084, 585, 1123], "text": "[1] V. Jayachandran, S. S. Murugan, P. A. Dalavi, Y. D. Gurushanthappa Vishalakshi, Gi H Seong, Curr. Pharm. Des. 2022, 28, 1067.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [1] V. Jayachandran, S. S. Murugan, P. A. Dalavi, Y. D. Guru"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [1] V. Jayachandran, S. S. Murugan, P. A. Dalavi, Y. D. Guru"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 12, "page": 23, "raw_label": "reference_content", "text": "[1] V. Jayachandran, S. S. Murugan, P. A. Dalavi, Y. D. Gurushanthappa Vishalakshi, Gi H Seong, Curr. Pharm. Des. 2022, 28, 1067.", "bbox": [115, 1084, 585, 1123], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[1]", "number": 1, "kind": "reference", "normalized_text": "[1] V. Jayachandran, S. S. Murugan, P. A. Dalavi, Y. D. Gurushanthappa Vishalakshi, Gi H Seong, Curr. Pharm. Des. 2022, 28, 1067."}, "layout_signature": {"width": 470, "width_bucket": 475, "height": 39, "left": 115, "top": 1084, "right": 585, "bottom": 1123, "x_center": 350.0, "x_center_bucket": 350, "y_center": 1103.5, "x_ratio": 0.2939, "y_ratio": 0.7051, "width_ratio": 0.3946, "height_ratio": 0.0249, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 9}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_142", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 23, "block_id": 13, "raw_label": "reference_content", "raw_order": 11, "bbox": [115, 1124, 585, 1180], "text": "[2] J.-N. Fu, X. Wang, M. Yang, Y.-R. Chen, Ji-Y Zhang, R.-H. Deng, Zi-N Zhang, J.-K. Yu, Fu-Z Yuan, Front. Bioeng. Biotechnol. 2021, 9, 812383.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [2] J.-N. Fu, X. Wang, M. Yang, Y.-R. Chen, Ji-Y Zhang, R.-H"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [2] J.-N. Fu, X. Wang, M. Yang, Y.-R. Chen, Ji-Y Zhang, R.-H"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 13, "page": 23, "raw_label": "reference_content", "text": "[2] J.-N. Fu, X. Wang, M. Yang, Y.-R. Chen, Ji-Y Zhang, R.-H. Deng, Zi-N Zhang, J.-K. Yu, Fu-Z Yuan, Front. Bioeng. Biotechnol. 2021, 9, 812383.", "bbox": [115, 1124, 585, 1180], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[2]", "number": 2, "kind": "reference", "normalized_text": "[2] J.-N. Fu, X. Wang, M. Yang, Y.-R. Chen, Ji-Y Zhang, R.-H. Deng, Zi-N Zhang, J.-K. Yu, Fu-Z Yuan, Front. Bioeng. Biotechnol. 2021, 9, 812383."}, "layout_signature": {"width": 470, "width_bucket": 475, "height": 56, "left": 115, "top": 1124, "right": 585, "bottom": 1180, "x_center": 350.0, "x_center_bucket": 350, "y_center": 1152.0, "x_ratio": 0.2939, "y_ratio": 0.7361, "width_ratio": 0.3946, "height_ratio": 0.0358, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 27}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_136", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 23, "block_id": 14, "raw_label": "reference_content", "raw_order": 12, "bbox": [115, 1183, 523, 1204], "text": "[3] C. Wang, H. Wang, B. Xu, H. Liu, View 2020, 2, 20200045.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [3] C. Wang, H. Wang, B. Xu, H. Liu, View 2020, 2, 20200045."], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [3] C. Wang, H. Wang, B. Xu, H. Liu, View 2020, 2, 20200045."], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 14, "page": 23, "raw_label": "reference_content", "text": "[3] C. Wang, H. Wang, B. Xu, H. Liu, View 2020, 2, 20200045.", "bbox": [115, 1183, 523, 1204], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[3]", "number": 3, "kind": "reference", "normalized_text": "[3] C. Wang, H. Wang, B. Xu, H. Liu, View 2020, 2, 20200045."}, "layout_signature": {"width": 408, "width_bucket": 400, "height": 21, "left": 115, "top": 1183, "right": 523, "bottom": 1204, "x_center": 319.0, "x_center_bucket": 325, "y_center": 1193.5, "x_ratio": 0.2678, "y_ratio": 0.7626, "width_ratio": 0.3426, "height_ratio": 0.0134, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 8}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_136", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 23, "block_id": 15, "raw_label": "reference_content", "raw_order": 13, "bbox": [116, 1204, 403, 1223], "text": "[4] C. Qin, C. Wu, View 2022, 3, 20210018.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [4] C. Qin, C. Wu, View 2022, 3, 20210018."], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [4] C. Qin, C. Wu, View 2022, 3, 20210018."], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 15, "page": 23, "raw_label": "reference_content", "text": "[4] C. Qin, C. Wu, View 2022, 3, 20210018.", "bbox": [116, 1204, 403, 1223], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[4]", "number": 4, "kind": "reference", "normalized_text": "[4] C. Qin, C. Wu, View 2022, 3, 20210018."}, "layout_signature": {"width": 287, "width_bucket": 275, "height": 19, "left": 116, "top": 1204, "right": 403, "bottom": 1223, "x_center": 259.5, "x_center_bucket": 250, "y_center": 1213.5, "x_ratio": 0.2179, "y_ratio": 0.7754, "width_ratio": 0.241, "height_ratio": 0.0121, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 8}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_136", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 23, "block_id": 16, "raw_label": "reference_content", "raw_order": 14, "bbox": [115, 1223, 550, 1243], "text": "[5] E. Boanini, M. Gazzano, A. Bigi, Acta Biomater. 2010, 6, 1882.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [5] E. Boanini, M. Gazzano, A. Bigi, Acta Biomater. 2010, 6,"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [5] E. Boanini, M. Gazzano, A. Bigi, Acta Biomater. 2010, 6,"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 16, "page": 23, "raw_label": "reference_content", "text": "[5] E. Boanini, M. Gazzano, A. Bigi, Acta Biomater. 2010, 6, 1882.", "bbox": [115, 1223, 550, 1243], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[5]", "number": 5, "kind": "reference", "normalized_text": "[5] E. Boanini, M. Gazzano, A. Bigi, Acta Biomater. 2010, 6, 1882."}, "layout_signature": {"width": 435, "width_bucket": 425, "height": 20, "left": 115, "top": 1223, "right": 550, "bottom": 1243, "x_center": 332.5, "x_center_bucket": 325, "y_center": 1233.0, "x_ratio": 0.2792, "y_ratio": 0.7879, "width_ratio": 0.3652, "height_ratio": 0.0128, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 8}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_136", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 23, "block_id": 17, "raw_label": "reference_content", "raw_order": 15, "bbox": [116, 1244, 584, 1283], "text": "[6] H. Liu, H. Peng, Y. Wu, C. Zhang, Y. Cai, G. Xu, Q. Li, X. Chen, J. Ji, Y. Zhang, H. W. Ouyang, Biomaterials 2013, 34, 4404.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [6] H. Liu, H. Peng, Y. Wu, C. Zhang, Y. Cai, G. Xu, Q. Li, "], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [6] H. Liu, H. Peng, Y. Wu, C. Zhang, Y. Cai, G. Xu, Q. Li, "], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 17, "page": 23, "raw_label": "reference_content", "text": "[6] H. Liu, H. Peng, Y. Wu, C. Zhang, Y. Cai, G. Xu, Q. Li, X. Chen, J. Ji, Y. Zhang, H. W. Ouyang, Biomaterials 2013, 34, 4404.", "bbox": [116, 1244, 584, 1283], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[6]", "number": 6, "kind": "reference", "normalized_text": "[6] H. Liu, H. Peng, Y. Wu, C. Zhang, Y. Cai, G. Xu, Q. Li, X. Chen, J. Ji, Y. Zhang, H. W. Ouyang, Biomaterials 2013, 34, 4404."}, "layout_signature": {"width": 468, "width_bucket": 475, "height": 39, "left": 116, "top": 1244, "right": 584, "bottom": 1283, "x_center": 350.0, "x_center_bucket": 350, "y_center": 1263.5, "x_ratio": 0.2939, "y_ratio": 0.8073, "width_ratio": 0.3929, "height_ratio": 0.0249, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 9}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_136", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 23, "block_id": 18, "raw_label": "reference_content", "raw_order": 16, "bbox": [116, 1284, 469, 1303], "text": "[7] P. Fathi, L. Rao, X. Chen, View 2020, 2, 20200187.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [7] P. Fathi, L. Rao, X. Chen, View 2020, 2, 20200187."], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [7] P. Fathi, L. Rao, X. Chen, View 2020, 2, 20200187."], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 18, "page": 23, "raw_label": "reference_content", "text": "[7] P. Fathi, L. Rao, X. Chen, View 2020, 2, 20200187.", "bbox": [116, 1284, 469, 1303], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[7]", "number": 7, "kind": "reference", "normalized_text": "[7] P. Fathi, L. Rao, X. Chen, View 2020, 2, 20200187."}, "layout_signature": {"width": 353, "width_bucket": 350, "height": 19, "left": 116, "top": 1284, "right": 469, "bottom": 1303, "x_center": 292.5, "x_center_bucket": 300, "y_center": 1293.5, "x_ratio": 0.2456, "y_ratio": 0.8265, "width_ratio": 0.2964, "height_ratio": 0.0121, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 8}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_136", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 23, "block_id": 19, "raw_label": "reference_content", "raw_order": 17, "bbox": [117, 1304, 585, 1342], "text": "[8] N. Amiryaghoubi, M. Fathi, N. N. Pesyan, M. Samiei, J. Barar, Y. Omidi, Med. Res. Rev. 2020, 40, 1833.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [8] N. Amiryaghoubi, M. Fathi, N. N. Pesyan, M. Samiei, J. B"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [8] N. Amiryaghoubi, M. Fathi, N. N. Pesyan, M. Samiei, J. B"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 19, "page": 23, "raw_label": "reference_content", "text": "[8] N. Amiryaghoubi, M. Fathi, N. N. Pesyan, M. Samiei, J. Barar, Y. Omidi, Med. Res. Rev. 2020, 40, 1833.", "bbox": [117, 1304, 585, 1342], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[8]", "number": 8, "kind": "reference", "normalized_text": "[8] N. Amiryaghoubi, M. Fathi, N. N. Pesyan, M. Samiei, J. Barar, Y. Omidi, Med. Res. Rev. 2020, 40, 1833."}, "layout_signature": {"width": 468, "width_bucket": 475, "height": 38, "left": 117, "top": 1304, "right": 585, "bottom": 1342, "x_center": 351.0, "x_center_bucket": 350, "y_center": 1323.0, "x_ratio": 0.2947, "y_ratio": 0.8454, "width_ratio": 0.3929, "height_ratio": 0.0243, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 31}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_136", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 23, "block_id": 20, "raw_label": "reference_content", "raw_order": 18, "bbox": [111, 1344, 585, 1399], "text": "[9] M. Bahraminasab, M. Janmohammadi, S. Arab, A. Talebi, V. T. Nooshabadi, P. Koohsarian, M. S. Nourbakhsh, ACS Biomater. Sci. Eng. 2021, 7, 5397.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [9] M. Bahraminasab, M. Janmohammadi, S. Arab, A. Talebi, V."], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [9] M. Bahraminasab, M. Janmohammadi, S. Arab, A. Talebi, V."], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 20, "page": 23, "raw_label": "reference_content", "text": "[9] M. Bahraminasab, M. Janmohammadi, S. Arab, A. Talebi, V. T. Nooshabadi, P. Koohsarian, M. S. Nourbakhsh, ACS Biomater. Sci. Eng. 2021, 7, 5397.", "bbox": [111, 1344, 585, 1399], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[9]", "number": 9, "kind": "reference", "normalized_text": "[9] M. Bahraminasab, M. Janmohammadi, S. Arab, A. Talebi, V. T. Nooshabadi, P. Koohsarian, M. S. Nourbakhsh, ACS Biomater. Sci. Eng. 2021, 7, 5397."}, "layout_signature": {"width": 474, "width_bucket": 475, "height": 55, "left": 111, "top": 1344, "right": 585, "bottom": 1399, "x_center": 348.0, "x_center_bucket": 350, "y_center": 1371.5, "x_ratio": 0.2922, "y_ratio": 0.8764, "width_ratio": 0.398, "height_ratio": 0.0351, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 28}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_136", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 23, "block_id": 21, "raw_label": "reference_content", "raw_order": 19, "bbox": [108, 1402, 536, 1421], "text": "[10] H. Wang, S. Zhang, J. Lv, Y. Cheng, View 2021, 2, 20200026.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [10] H. Wang, S. Zhang, J. Lv, Y. Cheng, View 2021, 2, 20200"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [10] H. Wang, S. Zhang, J. Lv, Y. Cheng, View 2021, 2, 20200"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 21, "page": 23, "raw_label": "reference_content", "text": "[10] H. Wang, S. Zhang, J. Lv, Y. Cheng, View 2021, 2, 20200026.", "bbox": [108, 1402, 536, 1421], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[10]", "number": 10, "kind": "reference", "normalized_text": "[10] H. Wang, S. Zhang, J. Lv, Y. Cheng, View 2021, 2, 20200026."}, "layout_signature": {"width": 428, "width_bucket": 425, "height": 19, "left": 108, "top": 1402, "right": 536, "bottom": 1421, "x_center": 322.0, "x_center_bucket": 325, "y_center": 1411.5, "x_ratio": 0.2704, "y_ratio": 0.9019, "width_ratio": 0.3594, "height_ratio": 0.0121, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 8}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_133", "display_cluster_candidate_id": "disp_26_0", "layout_region": "display_zone", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 23, "block_id": 22, "raw_label": "reference_content", "raw_order": 20, "bbox": [108, 1424, 453, 1443], "text": "[11] X. Xu, S. Shen, R. Mo, View 2022, 3, 20200136.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [11] X. Xu, S. Shen, R. Mo, View 2022, 3, 20200136."], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [11] X. Xu, S. Shen, R. Mo, View 2022, 3, 20200136."], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 22, "page": 23, "raw_label": "reference_content", "text": "[11] X. Xu, S. Shen, R. Mo, View 2022, 3, 20200136.", "bbox": [108, 1424, 453, 1443], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[11]", "number": 11, "kind": "reference", "normalized_text": "[11] X. Xu, S. Shen, R. Mo, View 2022, 3, 20200136."}, "layout_signature": {"width": 345, "width_bucket": 350, "height": 19, "left": 108, "top": 1424, "right": 453, "bottom": 1443, "x_center": 280.5, "x_center_bucket": 275, "y_center": 1433.5, "x_ratio": 0.2355, "y_ratio": 0.916, "width_ratio": 0.2897, "height_ratio": 0.0121, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 8}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_134", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 23, "block_id": 23, "raw_label": "reference_content", "raw_order": 21, "bbox": [617, 150, 1096, 208], "text": "[12] É. R. Oliveira, L. Nie, D. Podstawczyk, A. Allahbakhsh, J. Ratnayake, D. L. Brasil, A. Shavandi, Int. J. Mol. Sci. 2021, 22, 903.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [12] É. R. Oliveira, L. Nie, D. Podstawczyk, A. Allahbakhsh,"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [12] É. R. Oliveira, L. Nie, D. Podstawczyk, A. Allahbakhsh,"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 23, "page": 23, "raw_label": "reference_content", "text": "[12] É. R. Oliveira, L. Nie, D. Podstawczyk, A. Allahbakhsh, J. Ratnayake, D. L. Brasil, A. Shavandi, Int. J. Mol. Sci. 2021, 22, 903.", "bbox": [617, 150, 1096, 208], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[12]", "number": 12, "kind": "reference", "normalized_text": "[12] É. R. Oliveira, L. Nie, D. Podstawczyk, A. Allahbakhsh, J. Ratnayake, D. L. Brasil, A. Shavandi, Int. J. Mol. Sci. 2021, 22, 903."}, "layout_signature": {"width": 479, "width_bucket": 475, "height": 58, "left": 617, "top": 150, "right": 1096, "bottom": 208, "x_center": 856.5, "x_center_bucket": 850, "y_center": 179.0, "x_ratio": 0.7191, "y_ratio": 0.1144, "width_ratio": 0.4022, "height_ratio": 0.0371, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 47}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_133", "display_cluster_candidate_id": "disp_26_0", "layout_region": "display_zone", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 23, "block_id": 24, "raw_label": "reference_content", "raw_order": 22, "bbox": [618, 210, 1096, 249], "text": "[13] K. Chen, H. Han, R. G. Tuguntaev, P. Wang, W. Guo, J. Huang, X. Gong, X.-J. Liang, View 2020, 2, 20200091.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [13] K. Chen, H. Han, R. G. Tuguntaev, P. Wang, W. Guo, J. H"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [13] K. Chen, H. Han, R. G. Tuguntaev, P. Wang, W. Guo, J. H"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 24, "page": 23, "raw_label": "reference_content", "text": "[13] K. Chen, H. Han, R. G. Tuguntaev, P. Wang, W. Guo, J. Huang, X. Gong, X.-J. Liang, View 2020, 2, 20200091.", "bbox": [618, 210, 1096, 249], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[13]", "number": 13, "kind": "reference", "normalized_text": "[13] K. Chen, H. Han, R. G. Tuguntaev, P. Wang, W. Guo, J. Huang, X. Gong, X.-J. Liang, View 2020, 2, 20200091."}, "layout_signature": {"width": 478, "width_bucket": 475, "height": 39, "left": 618, "top": 210, "right": 1096, "bottom": 249, "x_center": 857.0, "x_center_bucket": 850, "y_center": 229.5, "x_ratio": 0.7196, "y_ratio": 0.1466, "width_ratio": 0.4013, "height_ratio": 0.0249, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 35}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_134", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 23, "block_id": 25, "raw_label": "reference_content", "raw_order": 23, "bbox": [618, 251, 913, 270], "text": "[14] Y. Feng, Curr. Drug Deliv. 2021, 18, 847.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [14] Y. Feng, Curr. Drug Deliv. 2021, 18, 847."], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [14] Y. Feng, Curr. Drug Deliv. 2021, 18, 847."], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 25, "page": 23, "raw_label": "reference_content", "text": "[14] Y. Feng, Curr. Drug Deliv. 2021, 18, 847.", "bbox": [618, 251, 913, 270], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[14]", "number": 14, "kind": "reference", "normalized_text": "[14] Y. Feng, Curr. Drug Deliv. 2021, 18, 847."}, "layout_signature": {"width": 295, "width_bucket": 300, "height": 19, "left": 618, "top": 251, "right": 913, "bottom": 270, "x_center": 765.5, "x_center_bucket": 775, "y_center": 260.5, "x_ratio": 0.6427, "y_ratio": 0.1665, "width_ratio": 0.2477, "height_ratio": 0.0121, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 8}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_131", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 23, "block_id": 26, "raw_label": "reference_content", "raw_order": 24, "bbox": [618, 271, 1051, 290], "text": "[15] H. Wei, J. Cui, K. Lin, J. Xie, X. Wang, Bone Res. 2022, 10, 17.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [15] H. Wei, J. Cui, K. Lin, J. Xie, X. Wang, Bone Res. 2022"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [15] H. Wei, J. Cui, K. Lin, J. Xie, X. Wang, Bone Res. 2022"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 26, "page": 23, "raw_label": "reference_content", "text": "[15] H. Wei, J. Cui, K. Lin, J. Xie, X. Wang, Bone Res. 2022, 10, 17.", "bbox": [618, 271, 1051, 290], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[15]", "number": 15, "kind": "reference", "normalized_text": "[15] H. Wei, J. Cui, K. Lin, J. Xie, X. Wang, Bone Res. 2022, 10, 17."}, "layout_signature": {"width": 433, "width_bucket": 425, "height": 19, "left": 618, "top": 271, "right": 1051, "bottom": 290, "x_center": 834.5, "x_center_bucket": 825, "y_center": 280.5, "x_ratio": 0.7007, "y_ratio": 0.1792, "width_ratio": 0.3636, "height_ratio": 0.0121, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 8}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_135", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "hard", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 23, "block_id": 27, "raw_label": "reference_content", "raw_order": 25, "bbox": [619, 293, 1096, 329], "text": "[16] B. Wang, G. Li, Q. Zhu, W. Liu, W. Ke, W. Hua, Y. Zhou, X. Zeng, X. Sun, Z. Wen, C. Yang, Y. Pan, Small 2022, 18, 2201056.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [16] B. Wang, G. Li, Q. Zhu, W. Liu, W. Ke, W. Hua, Y. Zhou,"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [16] B. Wang, G. Li, Q. Zhu, W. Liu, W. Ke, W. Hua, Y. Zhou,"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 27, "page": 23, "raw_label": "reference_content", "text": "[16] B. Wang, G. Li, Q. Zhu, W. Liu, W. Ke, W. Hua, Y. Zhou, X. Zeng, X. Sun, Z. Wen, C. Yang, Y. Pan, Small 2022, 18, 2201056.", "bbox": [619, 293, 1096, 329], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[16]", "number": 16, "kind": "reference", "normalized_text": "[16] B. Wang, G. Li, Q. Zhu, W. Liu, W. Ke, W. Hua, Y. Zhou, X. Zeng, X. Sun, Z. Wen, C. Yang, Y. Pan, Small 2022, 18, 2201056."}, "layout_signature": {"width": 477, "width_bucket": 475, "height": 36, "left": 619, "top": 293, "right": 1096, "bottom": 329, "x_center": 857.5, "x_center_bucket": 850, "y_center": 311.0, "x_ratio": 0.72, "y_ratio": 0.1987, "width_ratio": 0.4005, "height_ratio": 0.023, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 9}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_137", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 23, "block_id": 28, "raw_label": "reference_content", "raw_order": 26, "bbox": [618, 330, 991, 350], "text": "[17] Di Zheng, K. Yang, Z. Nie, View 2021, 2, 20200067.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [17] Di Zheng, K. Yang, Z. Nie, View 2021, 2, 20200067."], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [17] Di Zheng, K. Yang, Z. Nie, View 2021, 2, 20200067."], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 28, "page": 23, "raw_label": "reference_content", "text": "[17] Di Zheng, K. Yang, Z. Nie, View 2021, 2, 20200067.", "bbox": [618, 330, 991, 350], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[17]", "number": 17, "kind": "reference", "normalized_text": "[17] Di Zheng, K. Yang, Z. Nie, View 2021, 2, 20200067."}, "layout_signature": {"width": 373, "width_bucket": 375, "height": 20, "left": 618, "top": 330, "right": 991, "bottom": 350, "x_center": 804.5, "x_center_bucket": 800, "y_center": 340.0, "x_ratio": 0.6755, "y_ratio": 0.2173, "width_ratio": 0.3132, "height_ratio": 0.0128, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 8}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_137", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 23, "block_id": 29, "raw_label": "reference_content", "raw_order": 27, "bbox": [618, 351, 1080, 370], "text": "[18] G. L. Koons, M. Diba, A. G. Mikos, Nat. Rev. Mater. 2020, 5, 584.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [18] G. L. Koons, M. Diba, A. G. Mikos, Nat. Rev. Mater. 202"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [18] G. L. Koons, M. Diba, A. G. Mikos, Nat. Rev. Mater. 202"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 29, "page": 23, "raw_label": "reference_content", "text": "[18] G. L. Koons, M. Diba, A. G. Mikos, Nat. Rev. Mater. 2020, 5, 584.", "bbox": [618, 351, 1080, 370], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[18]", "number": 18, "kind": "reference", "normalized_text": "[18] G. L. Koons, M. Diba, A. G. Mikos, Nat. Rev. Mater. 2020, 5, 584."}, "layout_signature": {"width": 462, "width_bucket": 450, "height": 19, "left": 618, "top": 351, "right": 1080, "bottom": 370, "x_center": 849.0, "x_center_bucket": 850, "y_center": 360.5, "x_ratio": 0.7128, "y_ratio": 0.2304, "width_ratio": 0.3879, "height_ratio": 0.0121, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 8}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_126", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 23, "block_id": 30, "raw_label": "reference_content", "raw_order": 28, "bbox": [619, 372, 1096, 407], "text": "[19] Y. Wang, H. Zhang, Y. Hu, Y. Jing, Z. Geng, J. Su, Adv. Funct. Mater. 2022, 32, 2208639.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [19] Y. Wang, H. Zhang, Y. Hu, Y. Jing, Z. Geng, J. Su, Adv."], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [19] Y. Wang, H. Zhang, Y. Hu, Y. Jing, Z. Geng, J. Su, Adv."], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 30, "page": 23, "raw_label": "reference_content", "text": "[19] Y. Wang, H. Zhang, Y. Hu, Y. Jing, Z. Geng, J. Su, Adv. Funct. Mater. 2022, 32, 2208639.", "bbox": [619, 372, 1096, 407], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[19]", "number": 19, "kind": "reference", "normalized_text": "[19] Y. Wang, H. Zhang, Y. Hu, Y. Jing, Z. Geng, J. Su, Adv. Funct. Mater. 2022, 32, 2208639."}, "layout_signature": {"width": 477, "width_bucket": 475, "height": 35, "left": 619, "top": 372, "right": 1096, "bottom": 407, "x_center": 857.5, "x_center_bucket": 850, "y_center": 389.5, "x_ratio": 0.72, "y_ratio": 0.2489, "width_ratio": 0.4005, "height_ratio": 0.0224, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 8}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_126", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 23, "block_id": 31, "raw_label": "reference_content", "raw_order": 29, "bbox": [619, 410, 1095, 448], "text": "[20] G. Kaur, V. Kumar, F. Baino, J. C. Mauro, G. Pickrell, I. Evans, O. Bretcanu, Mater. Sci. Eng. C-Mater. 2019, 104, 109895.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [20] G. Kaur, V. Kumar, F. Baino, J. C. Mauro, G. Pickrell, "], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [20] G. Kaur, V. Kumar, F. Baino, J. C. Mauro, G. Pickrell, "], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 31, "page": 23, "raw_label": "reference_content", "text": "[20] G. Kaur, V. Kumar, F. Baino, J. C. Mauro, G. Pickrell, I. Evans, O. Bretcanu, Mater. Sci. Eng. C-Mater. 2019, 104, 109895.", "bbox": [619, 410, 1095, 448], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[20]", "number": 20, "kind": "reference", "normalized_text": "[20] G. Kaur, V. Kumar, F. Baino, J. C. Mauro, G. Pickrell, I. Evans, O. Bretcanu, Mater. Sci. Eng. C-Mater. 2019, 104, 109895."}, "layout_signature": {"width": 476, "width_bucket": 475, "height": 38, "left": 619, "top": 410, "right": 1095, "bottom": 448, "x_center": 857.0, "x_center_bucket": 850, "y_center": 429.0, "x_ratio": 0.7196, "y_ratio": 0.2741, "width_ratio": 0.3997, "height_ratio": 0.0243, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 35}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_126", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 23, "block_id": 32, "raw_label": "reference_content", "raw_order": 30, "bbox": [617, 450, 1096, 507], "text": "[21] G. F. de Grado, L. Keller, Y. Idoux-Gillet, Q. Wagner, A. M. Musset, N. Benkirane-Jessel, F. Bornert, D. Offner, J. Tissue Eng. 2018, 9, 2041731418776819.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [21] G. F. de Grado, L. Keller, Y. Idoux-Gillet, Q. Wagner, "], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [21] G. F. de Grado, L. Keller, Y. Idoux-Gillet, Q. Wagner, "], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 32, "page": 23, "raw_label": "reference_content", "text": "[21] G. F. de Grado, L. Keller, Y. Idoux-Gillet, Q. Wagner, A. M. Musset, N. Benkirane-Jessel, F. Bornert, D. Offner, J. Tissue Eng. 2018, 9, 2041731418776819.", "bbox": [617, 450, 1096, 507], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[21]", "number": 21, "kind": "reference", "normalized_text": "[21] G. F. de Grado, L. Keller, Y. Idoux-Gillet, Q. Wagner, A. M. Musset, N. Benkirane-Jessel, F. Bornert, D. Offner, J. Tissue Eng. 2018, 9, 2041731418776819."}, "layout_signature": {"width": 479, "width_bucket": 475, "height": 57, "left": 617, "top": 450, "right": 1096, "bottom": 507, "x_center": 856.5, "x_center_bucket": 850, "y_center": 478.5, "x_ratio": 0.7191, "y_ratio": 0.3058, "width_ratio": 0.4022, "height_ratio": 0.0364, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 27}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_126", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 23, "block_id": 33, "raw_label": "reference_content", "raw_order": 31, "bbox": [618, 510, 1095, 548], "text": "[22] M. Dziadek, E. Stodolak-Zych, K. Cholewa-Kowalska, Mater. Sci. Eng. C Mater. Biol. Appl. 2017, 71, 1175.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [22] M. Dziadek, E. Stodolak-Zych, K. Cholewa-Kowalska, Mate"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [22] M. Dziadek, E. Stodolak-Zych, K. Cholewa-Kowalska, Mate"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 33, "page": 23, "raw_label": "reference_content", "text": "[22] M. Dziadek, E. Stodolak-Zych, K. Cholewa-Kowalska, Mater. Sci. Eng. C Mater. Biol. Appl. 2017, 71, 1175.", "bbox": [618, 510, 1095, 548], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[22]", "number": 22, "kind": "reference", "normalized_text": "[22] M. Dziadek, E. Stodolak-Zych, K. Cholewa-Kowalska, Mater. Sci. Eng. C Mater. Biol. Appl. 2017, 71, 1175."}, "layout_signature": {"width": 477, "width_bucket": 475, "height": 38, "left": 618, "top": 510, "right": 1095, "bottom": 548, "x_center": 856.5, "x_center_bucket": 850, "y_center": 529.0, "x_ratio": 0.7191, "y_ratio": 0.338, "width_ratio": 0.4005, "height_ratio": 0.0243, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 9}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_126", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 23, "block_id": 34, "raw_label": "reference_content", "raw_order": 32, "bbox": [619, 550, 1096, 587], "text": "[23] P. Sutthavas, Z. Tahmasebi Birgani, P. Habibovic, S. Van Rijt, Adv. Healthc. Mater. 2022, 11, e2101588.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [23] P. Sutthavas, Z. Tahmasebi Birgani, P. Habibovic, S. Va"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [23] P. Sutthavas, Z. Tahmasebi Birgani, P. Habibovic, S. Va"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 34, "page": 23, "raw_label": "reference_content", "text": "[23] P. Sutthavas, Z. Tahmasebi Birgani, P. Habibovic, S. Van Rijt, Adv. Healthc. Mater. 2022, 11, e2101588.", "bbox": [619, 550, 1096, 587], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[23]", "number": 23, "kind": "reference", "normalized_text": "[23] P. Sutthavas, Z. Tahmasebi Birgani, P. Habibovic, S. Van Rijt, Adv. Healthc. Mater. 2022, 11, e2101588."}, "layout_signature": {"width": 477, "width_bucket": 475, "height": 37, "left": 619, "top": 550, "right": 1096, "bottom": 587, "x_center": 857.5, "x_center_bucket": 850, "y_center": 568.5, "x_ratio": 0.72, "y_ratio": 0.3633, "width_ratio": 0.4005, "height_ratio": 0.0236, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 28}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_124", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 23, "block_id": 35, "raw_label": "reference_content", "raw_order": 33, "bbox": [618, 589, 1082, 609], "text": "[24] Y. Li, T. Jiang, Li Zheng, J. Zhao, Mater. Sci. Eng., C 2017, 80, 296.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [24] Y. Li, T. Jiang, Li Zheng, J. Zhao, Mater. Sci. Eng., C"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [24] Y. Li, T. Jiang, Li Zheng, J. Zhao, Mater. Sci. Eng., C"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 35, "page": 23, "raw_label": "reference_content", "text": "[24] Y. Li, T. Jiang, Li Zheng, J. Zhao, Mater. Sci. Eng., C 2017, 80, 296.", "bbox": [618, 589, 1082, 609], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[24]", "number": 24, "kind": "reference", "normalized_text": "[24] Y. Li, T. Jiang, Li Zheng, J. Zhao, Mater. Sci. Eng., C 2017, 80, 296."}, "layout_signature": {"width": 464, "width_bucket": 475, "height": 20, "left": 618, "top": 589, "right": 1082, "bottom": 609, "x_center": 850.0, "x_center_bucket": 850, "y_center": 599.0, "x_ratio": 0.7137, "y_ratio": 0.3827, "width_ratio": 0.3896, "height_ratio": 0.0128, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 8}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_127", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 23, "block_id": 36, "raw_label": "reference_content", "raw_order": 34, "bbox": [618, 611, 1097, 665], "text": "[25] X. Chen, Y. Liu, Y. Zhao, Z. Ouyang, H. Zhou, L. Li, L. Li, F. Li, X. Xie, R. G. Hill, S. Wang, X. Chen, Biomater. Adv. 2022, 143, 213173.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [25] X. Chen, Y. Liu, Y. Zhao, Z. Ouyang, H. Zhou, L. Li, L."], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [25] X. Chen, Y. Liu, Y. Zhao, Z. Ouyang, H. Zhou, L. Li, L."], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 36, "page": 23, "raw_label": "reference_content", "text": "[25] X. Chen, Y. Liu, Y. Zhao, Z. Ouyang, H. Zhou, L. Li, L. Li, F. Li, X. Xie, R. G. Hill, S. Wang, X. Chen, Biomater. Adv. 2022, 143, 213173.", "bbox": [618, 611, 1097, 665], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[25]", "number": 25, "kind": "reference", "normalized_text": "[25] X. Chen, Y. Liu, Y. Zhao, Z. Ouyang, H. Zhou, L. Li, L. Li, F. Li, X. Xie, R. G. Hill, S. Wang, X. Chen, Biomater. Adv. 2022, 143, 213173."}, "layout_signature": {"width": 479, "width_bucket": 475, "height": 54, "left": 618, "top": 611, "right": 1097, "bottom": 665, "x_center": 857.5, "x_center_bucket": 850, "y_center": 638.0, "x_ratio": 0.72, "y_ratio": 0.4077, "width_ratio": 0.4022, "height_ratio": 0.0345, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 61}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_127", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 23, "block_id": 37, "raw_label": "reference_content", "raw_order": 35, "bbox": [618, 669, 1050, 689], "text": "[26] C. Gao, S. Peng, P. Feng, C. Shuai, Bone Res. 2017, 5, 17059.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [26] C. Gao, S. Peng, P. Feng, C. Shuai, Bone Res. 2017, 5, "], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [26] C. Gao, S. Peng, P. Feng, C. Shuai, Bone Res. 2017, 5, "], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 37, "page": 23, "raw_label": "reference_content", "text": "[26] C. Gao, S. Peng, P. Feng, C. Shuai, Bone Res. 2017, 5, 17059.", "bbox": [618, 669, 1050, 689], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[26]", "number": 26, "kind": "reference", "normalized_text": "[26] C. Gao, S. Peng, P. Feng, C. Shuai, Bone Res. 2017, 5, 17059."}, "layout_signature": {"width": 432, "width_bucket": 425, "height": 20, "left": 618, "top": 669, "right": 1050, "bottom": 689, "x_center": 834.0, "x_center_bucket": 825, "y_center": 679.0, "x_ratio": 0.7003, "y_ratio": 0.4339, "width_ratio": 0.3627, "height_ratio": 0.0128, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 8}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_127", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 23, "block_id": 38, "raw_label": "reference_content", "raw_order": 36, "bbox": [618, 690, 1096, 745], "text": "[27] I. R. Bordea, S. Candrea, G. T. Alexescu, S. Bran, M. Baciu?, G. Baciu?, O. Lucaciu, C. M. Dinu, D. A. Todea, Drug Metab. Rev. 2020, 52, 319.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [27] I. R. Bordea, S. Candrea, G. T. Alexescu, S. Bran, M. B"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [27] I. R. Bordea, S. Candrea, G. T. Alexescu, S. Bran, M. B"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 38, "page": 23, "raw_label": "reference_content", "text": "[27] I. R. Bordea, S. Candrea, G. T. Alexescu, S. Bran, M. Baciu?, G. Baciu?, O. Lucaciu, C. M. Dinu, D. A. Todea, Drug Metab. Rev. 2020, 52, 319.", "bbox": [618, 690, 1096, 745], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[27]", "number": 27, "kind": "reference", "normalized_text": "[27] I. R. Bordea, S. Candrea, G. T. Alexescu, S. Bran, M. Baciu?, G. Baciu?, O. Lucaciu, C. M. Dinu, D. A. Todea, Drug Metab. Rev. 2020, 52, 319."}, "layout_signature": {"width": 478, "width_bucket": 475, "height": 55, "left": 618, "top": 690, "right": 1096, "bottom": 745, "x_center": 857.0, "x_center_bucket": 850, "y_center": 717.5, "x_ratio": 0.7196, "y_ratio": 0.4585, "width_ratio": 0.4013, "height_ratio": 0.0351, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 33}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_127", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 23, "block_id": 39, "raw_label": "reference_content", "raw_order": 37, "bbox": [618, 749, 1095, 787], "text": "[28] M. Bahraminasab, N. Doostmohammadi, A. Alizadeh, Int. J. Appl. Ceram. Technol. 2021, 18, 573.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [28] M. Bahraminasab, N. Doostmohammadi, A. Alizadeh, Int. J"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [28] M. Bahraminasab, N. Doostmohammadi, A. Alizadeh, Int. J"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 39, "page": 23, "raw_label": "reference_content", "text": "[28] M. Bahraminasab, N. Doostmohammadi, A. Alizadeh, Int. J. Appl. Ceram. Technol. 2021, 18, 573.", "bbox": [618, 749, 1095, 787], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[28]", "number": 28, "kind": "reference", "normalized_text": "[28] M. Bahraminasab, N. Doostmohammadi, A. Alizadeh, Int. J. Appl. Ceram. Technol. 2021, 18, 573."}, "layout_signature": {"width": 477, "width_bucket": 475, "height": 38, "left": 618, "top": 749, "right": 1095, "bottom": 787, "x_center": 856.5, "x_center_bucket": 850, "y_center": 768.0, "x_ratio": 0.7191, "y_ratio": 0.4907, "width_ratio": 0.4005, "height_ratio": 0.0243, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 24}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_127", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 23, "block_id": 40, "raw_label": "reference_content", "raw_order": 38, "bbox": [618, 789, 1096, 827], "text": "[29] D. Xiao, J. Zhang, C. Zhang, D. Barbieri, H. Yuan, L. Moroni, G. Feng, Acta Biomater. 2020, 106, 22.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [29] D. Xiao, J. Zhang, C. Zhang, D. Barbieri, H. Yuan, L. M"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [29] D. Xiao, J. Zhang, C. Zhang, D. Barbieri, H. Yuan, L. M"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 40, "page": 23, "raw_label": "reference_content", "text": "[29] D. Xiao, J. Zhang, C. Zhang, D. Barbieri, H. Yuan, L. Moroni, G. Feng, Acta Biomater. 2020, 106, 22.", "bbox": [618, 789, 1096, 827], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[29]", "number": 29, "kind": "reference", "normalized_text": "[29] D. Xiao, J. Zhang, C. Zhang, D. Barbieri, H. Yuan, L. Moroni, G. Feng, Acta Biomater. 2020, 106, 22."}, "layout_signature": {"width": 478, "width_bucket": 475, "height": 38, "left": 618, "top": 789, "right": 1096, "bottom": 827, "x_center": 857.0, "x_center_bucket": 850, "y_center": 808.0, "x_ratio": 0.7196, "y_ratio": 0.5163, "width_ratio": 0.4013, "height_ratio": 0.0243, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 8}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_127", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 23, "block_id": 41, "raw_label": "reference_content", "raw_order": 39, "bbox": [619, 829, 1096, 886], "text": "[30] H. D. Kim, H. L. Jang, H.-Y. Ahn, H. K. Lee, J. Park, E.-S. Lee, E. A. Lee, Y.-H. Jeong, Do-G Kim, Ki T Nam, N. S. Hwang, Biomaterials 2017, 112, 31.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [30] H. D. Kim, H. L. Jang, H.-Y. Ahn, H. K. Lee, J. Park, E"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [30] H. D. Kim, H. L. Jang, H.-Y. Ahn, H. K. Lee, J. Park, E"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 41, "page": 23, "raw_label": "reference_content", "text": "[30] H. D. Kim, H. L. Jang, H.-Y. Ahn, H. K. Lee, J. Park, E.-S. Lee, E. A. Lee, Y.-H. Jeong, Do-G Kim, Ki T Nam, N. S. Hwang, Biomaterials 2017, 112, 31.", "bbox": [619, 829, 1096, 886], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[30]", "number": 30, "kind": "reference", "normalized_text": "[30] H. D. Kim, H. L. Jang, H.-Y. Ahn, H. K. Lee, J. Park, E.-S. Lee, E. A. Lee, Y.-H. Jeong, Do-G Kim, Ki T Nam, N. S. Hwang, Biomaterials 2017, 112, 31."}, "layout_signature": {"width": 477, "width_bucket": 475, "height": 57, "left": 619, "top": 829, "right": 1096, "bottom": 886, "x_center": 857.5, "x_center_bucket": 850, "y_center": 857.5, "x_ratio": 0.72, "y_ratio": 0.5479, "width_ratio": 0.4005, "height_ratio": 0.0364, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 30}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_127", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 23, "block_id": 42, "raw_label": "reference_content", "raw_order": 40, "bbox": [618, 889, 1096, 928], "text": "[31] Z. Wu, Z. Meng, Q. Wu, D. Zeng, Z. Guo, J. Yao, Y. Bian, Y. Gu, S. Cheng, L. Peng, Y. Zhao, J. Tissue Eng. 2020, 11, 204173142096779.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [31] Z. Wu, Z. Meng, Q. Wu, D. Zeng, Z. Guo, J. Yao, Y. Bian"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [31] Z. Wu, Z. Meng, Q. Wu, D. Zeng, Z. Guo, J. Yao, Y. Bian"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 42, "page": 23, "raw_label": "reference_content", "text": "[31] Z. Wu, Z. Meng, Q. Wu, D. Zeng, Z. Guo, J. Yao, Y. Bian, Y. Gu, S. Cheng, L. Peng, Y. Zhao, J. Tissue Eng. 2020, 11, 204173142096779.", "bbox": [618, 889, 1096, 928], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[31]", "number": 31, "kind": "reference", "normalized_text": "[31] Z. Wu, Z. Meng, Q. Wu, D. Zeng, Z. Guo, J. Yao, Y. Bian, Y. Gu, S. Cheng, L. Peng, Y. Zhao, J. Tissue Eng. 2020, 11, 204173142096779."}, "layout_signature": {"width": 478, "width_bucket": 475, "height": 39, "left": 618, "top": 889, "right": 1096, "bottom": 928, "x_center": 857.0, "x_center_bucket": 850, "y_center": 908.5, "x_ratio": 0.7196, "y_ratio": 0.5805, "width_ratio": 0.4013, "height_ratio": 0.0249, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 39}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_127", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 23, "block_id": 43, "raw_label": "reference_content", "raw_order": 41, "bbox": [619, 929, 1095, 967], "text": "[32] B. Zhang, X. Pei, P. Song, H. Sun, H. Li, Y. Fan, Q. Jiang, C. Zhou, X. Zhang, Composites, Part B 2018, 155, 112.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [32] B. Zhang, X. Pei, P. Song, H. Sun, H. Li, Y. Fan, Q. Ji"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [32] B. Zhang, X. Pei, P. Song, H. Sun, H. Li, Y. Fan, Q. Ji"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 43, "page": 23, "raw_label": "reference_content", "text": "[32] B. Zhang, X. Pei, P. Song, H. Sun, H. Li, Y. Fan, Q. Jiang, C. Zhou, X. Zhang, Composites, Part B 2018, 155, 112.", "bbox": [619, 929, 1095, 967], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[32]", "number": 32, "kind": "reference", "normalized_text": "[32] B. Zhang, X. Pei, P. Song, H. Sun, H. Li, Y. Fan, Q. Jiang, C. Zhou, X. Zhang, Composites, Part B 2018, 155, 112."}, "layout_signature": {"width": 476, "width_bucket": 475, "height": 38, "left": 619, "top": 929, "right": 1095, "bottom": 967, "x_center": 857.0, "x_center_bucket": 850, "y_center": 948.0, "x_ratio": 0.7196, "y_ratio": 0.6058, "width_ratio": 0.3997, "height_ratio": 0.0243, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 9}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_127", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 23, "block_id": 44, "raw_label": "reference_content", "raw_order": 42, "bbox": [618, 969, 1095, 1005], "text": "[33] S. Makishi, T. Watanabe, K. Saito, H. Ohshima, Int. J. Mol. Sci. 2023, 24, 3124.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [33] S. Makishi, T. Watanabe, K. Saito, H. Ohshima, Int. J. "], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [33] S. Makishi, T. Watanabe, K. Saito, H. Ohshima, Int. J. "], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 44, "page": 23, "raw_label": "reference_content", "text": "[33] S. Makishi, T. Watanabe, K. Saito, H. Ohshima, Int. J. Mol. Sci. 2023, 24, 3124.", "bbox": [618, 969, 1095, 1005], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[33]", "number": 33, "kind": "reference", "normalized_text": "[33] S. Makishi, T. Watanabe, K. Saito, H. Ohshima, Int. J. Mol. Sci. 2023, 24, 3124."}, "layout_signature": {"width": 477, "width_bucket": 475, "height": 36, "left": 618, "top": 969, "right": 1095, "bottom": 1005, "x_center": 856.5, "x_center_bucket": 850, "y_center": 987.0, "x_ratio": 0.7191, "y_ratio": 0.6307, "width_ratio": 0.4005, "height_ratio": 0.023, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 8}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_127", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 23, "block_id": 45, "raw_label": "reference_content", "raw_order": 43, "bbox": [619, 1008, 1095, 1047], "text": "[34] H. D. Kim, S. Amirthalingam, S. L. Kim, S. S. Lee, J. Rangasamy, N. S. Hwang, Adv. Healthc. Mater. 2017, 6, 1700612.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [34] H. D. Kim, S. Amirthalingam, S. L. Kim, S. S. Lee, J. R"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [34] H. D. Kim, S. Amirthalingam, S. L. Kim, S. S. Lee, J. R"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 45, "page": 23, "raw_label": "reference_content", "text": "[34] H. D. Kim, S. Amirthalingam, S. L. Kim, S. S. Lee, J. Rangasamy, N. S. Hwang, Adv. Healthc. Mater. 2017, 6, 1700612.", "bbox": [619, 1008, 1095, 1047], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[34]", "number": 34, "kind": "reference", "normalized_text": "[34] H. D. Kim, S. Amirthalingam, S. L. Kim, S. S. Lee, J. Rangasamy, N. S. Hwang, Adv. Healthc. Mater. 2017, 6, 1700612."}, "layout_signature": {"width": 476, "width_bucket": 475, "height": 39, "left": 619, "top": 1008, "right": 1095, "bottom": 1047, "x_center": 857.0, "x_center_bucket": 850, "y_center": 1027.5, "x_ratio": 0.7196, "y_ratio": 0.6565, "width_ratio": 0.3997, "height_ratio": 0.0249, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 9}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_127", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 23, "block_id": 46, "raw_label": "reference_content", "raw_order": 44, "bbox": [618, 1049, 1096, 1106], "text": "[35] A. Kumar, S. M. Mir, I. Aldulijan, A. Mahajan, A. Anwar, C. H. Leon, A. Terracciano, X. Zhao, T.-L. Su, D. M. Kalyon, S. G. Kumar, X. Yu, J. Biomed. Mater. Res. B Appl. Biomater. 2021, 109, 193.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [35] A. Kumar, S. M. Mir, I. Aldulijan, A. Mahajan, A. Anwar"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [35] A. Kumar, S. M. Mir, I. Aldulijan, A. Mahajan, A. Anwar"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 46, "page": 23, "raw_label": "reference_content", "text": "[35] A. Kumar, S. M. Mir, I. Aldulijan, A. Mahajan, A. Anwar, C. H. Leon, A. Terracciano, X. Zhao, T.-L. Su, D. M. Kalyon, S. G. Kumar, X. Yu, J. Biomed. Mater. Res. B Appl. Biomater. 2021, 109, 193.", "bbox": [618, 1049, 1096, 1106], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[35]", "number": 35, "kind": "reference", "normalized_text": "[35] A. Kumar, S. M. Mir, I. Aldulijan, A. Mahajan, A. Anwar, C. H. Leon, A. Terracciano, X. Zhao, T.-L. Su, D. M. Kalyon, S. G. Kumar, X. Yu, J. Biomed. Mater. Res. B Appl. Biomater. 2021, 109, 193."}, "layout_signature": {"width": 478, "width_bucket": 475, "height": 57, "left": 618, "top": 1049, "right": 1096, "bottom": 1106, "x_center": 857.0, "x_center_bucket": 850, "y_center": 1077.5, "x_ratio": 0.7196, "y_ratio": 0.6885, "width_ratio": 0.4013, "height_ratio": 0.0364, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 9}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_127", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 23, "block_id": 47, "raw_label": "reference_content", "raw_order": 45, "bbox": [617, 1108, 1097, 1146], "text": "[36] M. Ebrahimi, M. G. Botelho, S. V. Dorozhkin, Mater. Sci. Eng., C 2017, 71, 1293.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [36] M. Ebrahimi, M. G. Botelho, S. V. Dorozhkin, Mater. Sci"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [36] M. Ebrahimi, M. G. Botelho, S. V. Dorozhkin, Mater. Sci"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 47, "page": 23, "raw_label": "reference_content", "text": "[36] M. Ebrahimi, M. G. Botelho, S. V. Dorozhkin, Mater. Sci. Eng., C 2017, 71, 1293.", "bbox": [617, 1108, 1097, 1146], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[36]", "number": 36, "kind": "reference", "normalized_text": "[36] M. Ebrahimi, M. G. Botelho, S. V. Dorozhkin, Mater. Sci. Eng., C 2017, 71, 1293."}, "layout_signature": {"width": 480, "width_bucket": 475, "height": 38, "left": 617, "top": 1108, "right": 1097, "bottom": 1146, "x_center": 857.0, "x_center_bucket": 850, "y_center": 1127.0, "x_ratio": 0.7196, "y_ratio": 0.7201, "width_ratio": 0.403, "height_ratio": 0.0243, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 29}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_127", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 23, "block_id": 48, "raw_label": "reference_content", "raw_order": 46, "bbox": [618, 1148, 1096, 1185], "text": "[37] J. M. Bouler, P. Pilet, O. Gauthier, E. Verron, Acta Biomater. 2017, 53, 1.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [37] J. M. Bouler, P. Pilet, O. Gauthier, E. Verron, Acta Bi"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [37] J. M. Bouler, P. Pilet, O. Gauthier, E. Verron, Acta Bi"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 48, "page": 23, "raw_label": "reference_content", "text": "[37] J. M. Bouler, P. Pilet, O. Gauthier, E. Verron, Acta Biomater. 2017, 53, 1.", "bbox": [618, 1148, 1096, 1185], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[37]", "number": 37, "kind": "reference", "normalized_text": "[37] J. M. Bouler, P. Pilet, O. Gauthier, E. Verron, Acta Biomater. 2017, 53, 1."}, "layout_signature": {"width": 478, "width_bucket": 475, "height": 37, "left": 618, "top": 1148, "right": 1096, "bottom": 1185, "x_center": 857.0, "x_center_bucket": 850, "y_center": 1166.5, "x_ratio": 0.7196, "y_ratio": 0.7454, "width_ratio": 0.4013, "height_ratio": 0.0236, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 28}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_127", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 23, "block_id": 49, "raw_label": "reference_content", "raw_order": 47, "bbox": [618, 1188, 1018, 1207], "text": "[38] S. E. Kim, K. Park, Adv. Exp. Med. Biol. 2020, 1250, 177.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [38] S. E. Kim, K. Park, Adv. Exp. Med. Biol. 2020, 1250, 17"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [38] S. E. Kim, K. Park, Adv. Exp. Med. Biol. 2020, 1250, 17"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 49, "page": 23, "raw_label": "reference_content", "text": "[38] S. E. Kim, K. Park, Adv. Exp. Med. Biol. 2020, 1250, 177.", "bbox": [618, 1188, 1018, 1207], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[38]", "number": 38, "kind": "reference", "normalized_text": "[38] S. E. Kim, K. Park, Adv. Exp. Med. Biol. 2020, 1250, 177."}, "layout_signature": {"width": 400, "width_bucket": 400, "height": 19, "left": 618, "top": 1188, "right": 1018, "bottom": 1207, "x_center": 818.0, "x_center_bucket": 825, "y_center": 1197.5, "x_ratio": 0.6868, "y_ratio": 0.7652, "width_ratio": 0.3359, "height_ratio": 0.0121, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 8}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_126", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 23, "block_id": 50, "raw_label": "reference_content", "raw_order": 48, "bbox": [619, 1209, 1096, 1246], "text": "[39] X. Li, T. Song, X. Chen, M. Wang, X. Yang, Y. Xiao, X. Zhang, ACS Appl. Mater. Interfaces 2019, 11, 3722.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [39] X. Li, T. Song, X. Chen, M. Wang, X. Yang, Y. Xiao, X. "], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [39] X. Li, T. Song, X. Chen, M. Wang, X. Yang, Y. Xiao, X. "], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 50, "page": 23, "raw_label": "reference_content", "text": "[39] X. Li, T. Song, X. Chen, M. Wang, X. Yang, Y. Xiao, X. Zhang, ACS Appl. Mater. Interfaces 2019, 11, 3722.", "bbox": [619, 1209, 1096, 1246], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[39]", "number": 39, "kind": "reference", "normalized_text": "[39] X. Li, T. Song, X. Chen, M. Wang, X. Yang, Y. Xiao, X. Zhang, ACS Appl. Mater. Interfaces 2019, 11, 3722."}, "layout_signature": {"width": 477, "width_bucket": 475, "height": 37, "left": 619, "top": 1209, "right": 1096, "bottom": 1246, "x_center": 857.5, "x_center_bucket": 850, "y_center": 1227.5, "x_ratio": 0.72, "y_ratio": 0.7843, "width_ratio": 0.4005, "height_ratio": 0.0236, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 36}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_127", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 23, "block_id": 51, "raw_label": "reference_content", "raw_order": 49, "bbox": [618, 1247, 1096, 1285], "text": "[40] V. Mouriño, R. Vidotto, J. P. Cattalini, A. R. Boccaccini, Curr. Opin. Biomed. Eng. 2019, 10, 23.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [40] V. Mouriño, R. Vidotto, J. P. Cattalini, A. R. Boccacci"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [40] V. Mouriño, R. Vidotto, J. P. Cattalini, A. R. Boccacci"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 51, "page": 23, "raw_label": "reference_content", "text": "[40] V. Mouriño, R. Vidotto, J. P. Cattalini, A. R. Boccaccini, Curr. Opin. Biomed. Eng. 2019, 10, 23.", "bbox": [618, 1247, 1096, 1285], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[40]", "number": 40, "kind": "reference", "normalized_text": "[40] V. Mouriño, R. Vidotto, J. P. Cattalini, A. R. Boccaccini, Curr. Opin. Biomed. Eng. 2019, 10, 23."}, "layout_signature": {"width": 478, "width_bucket": 475, "height": 38, "left": 618, "top": 1247, "right": 1096, "bottom": 1285, "x_center": 857.0, "x_center_bucket": 850, "y_center": 1266.0, "x_ratio": 0.7196, "y_ratio": 0.8089, "width_ratio": 0.4013, "height_ratio": 0.0243, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 30}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_127", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 23, "block_id": 52, "raw_label": "reference_content", "raw_order": 50, "bbox": [618, 1287, 1096, 1323], "text": "[41] J.-J. Kim, A. El-Fiqi, H.-W. Kim, ACS Appl. Mater. Interfaces 2017, 9, 2059.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [41] J.-J. Kim, A. El-Fiqi, H.-W. Kim, ACS Appl. Mater. Inte"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [41] J.-J. Kim, A. El-Fiqi, H.-W. Kim, ACS Appl. Mater. Inte"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 52, "page": 23, "raw_label": "reference_content", "text": "[41] J.-J. Kim, A. El-Fiqi, H.-W. Kim, ACS Appl. Mater. Interfaces 2017, 9, 2059.", "bbox": [618, 1287, 1096, 1323], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[41]", "number": 41, "kind": "reference", "normalized_text": "[41] J.-J. Kim, A. El-Fiqi, H.-W. Kim, ACS Appl. Mater. Interfaces 2017, 9, 2059."}, "layout_signature": {"width": 478, "width_bucket": 475, "height": 36, "left": 618, "top": 1287, "right": 1096, "bottom": 1323, "x_center": 857.0, "x_center_bucket": 850, "y_center": 1305.0, "x_ratio": 0.7196, "y_ratio": 0.8339, "width_ratio": 0.4013, "height_ratio": 0.023, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 9}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_127", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 23, "block_id": 53, "raw_label": "reference_content", "raw_order": 51, "bbox": [618, 1327, 1096, 1364], "text": "[42] F. Zhao, Bo Lei, X. Li, Y. Mo, R. Wang, D. Chen, X. Chen, Biomaterials 2018, 178, 36.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [42] F. Zhao, Bo Lei, X. Li, Y. Mo, R. Wang, D. Chen, X. Che"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [42] F. Zhao, Bo Lei, X. Li, Y. Mo, R. Wang, D. Chen, X. Che"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 53, "page": 23, "raw_label": "reference_content", "text": "[42] F. Zhao, Bo Lei, X. Li, Y. Mo, R. Wang, D. Chen, X. Chen, Biomaterials 2018, 178, 36.", "bbox": [618, 1327, 1096, 1364], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[42]", "number": 42, "kind": "reference", "normalized_text": "[42] F. Zhao, Bo Lei, X. Li, Y. Mo, R. Wang, D. Chen, X. Chen, Biomaterials 2018, 178, 36."}, "layout_signature": {"width": 478, "width_bucket": 475, "height": 37, "left": 618, "top": 1327, "right": 1096, "bottom": 1364, "x_center": 857.0, "x_center_bucket": 850, "y_center": 1345.5, "x_ratio": 0.7196, "y_ratio": 0.8597, "width_ratio": 0.4013, "height_ratio": 0.0236, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 8}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_127", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 23, "block_id": 54, "raw_label": "reference_content", "raw_order": 52, "bbox": [618, 1367, 1096, 1405], "text": "[43] Á. J. Leite, A. I. Gonçalves, M. T. Rodrigues, M. E. Gomes, J. F. Mano, ACS Appl. Mater. Interfaces 2018, 10, 23311.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [43] Á. J. Leite, A. I. Gonçalves, M. T. Rodrigues, M. E. Go"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [43] Á. J. Leite, A. I. Gonçalves, M. T. Rodrigues, M. E. Go"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 54, "page": 23, "raw_label": "reference_content", "text": "[43] Á. J. Leite, A. I. Gonçalves, M. T. Rodrigues, M. E. Gomes, J. F. Mano, ACS Appl. Mater. Interfaces 2018, 10, 23311.", "bbox": [618, 1367, 1096, 1405], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[43]", "number": 43, "kind": "reference", "normalized_text": "[43] Á. J. Leite, A. I. Gonçalves, M. T. Rodrigues, M. E. Gomes, J. F. Mano, ACS Appl. Mater. Interfaces 2018, 10, 23311."}, "layout_signature": {"width": 478, "width_bucket": 475, "height": 38, "left": 618, "top": 1367, "right": 1096, "bottom": 1405, "x_center": 857.0, "x_center_bucket": 850, "y_center": 1386.0, "x_ratio": 0.7196, "y_ratio": 0.8856, "width_ratio": 0.4013, "height_ratio": 0.0243, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 8}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_127", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 23, "block_id": 55, "raw_label": "reference_content", "raw_order": 53, "bbox": [618, 1408, 1095, 1446], "text": "[44] S. Fiorilli, G. Molino, C. Pontremoli, G. Iviglia, E. Torre, C. Cassinelli, M. Morra, C. Vitale-Brovarone, Materials 2018, 11, 678.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [44] S. Fiorilli, G. Molino, C. Pontremoli, G. Iviglia, E. T"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [44] S. Fiorilli, G. Molino, C. Pontremoli, G. Iviglia, E. T"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 55, "page": 23, "raw_label": "reference_content", "text": "[44] S. Fiorilli, G. Molino, C. Pontremoli, G. Iviglia, E. Torre, C. Cassinelli, M. Morra, C. Vitale-Brovarone, Materials 2018, 11, 678.", "bbox": [618, 1408, 1095, 1446], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[44]", "number": 44, "kind": "reference", "normalized_text": "[44] S. Fiorilli, G. Molino, C. Pontremoli, G. Iviglia, E. Torre, C. Cassinelli, M. Morra, C. Vitale-Brovarone, Materials 2018, 11, 678."}, "layout_signature": {"width": 477, "width_bucket": 475, "height": 38, "left": 618, "top": 1408, "right": 1095, "bottom": 1446, "x_center": 856.5, "x_center_bucket": 850, "y_center": 1427.0, "x_ratio": 0.7191, "y_ratio": 0.9118, "width_ratio": 0.4005, "height_ratio": 0.0243, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 9}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_127", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 23, "block_id": 56, "raw_label": "footer", "raw_order": null, "bbox": [99, 1488, 288, 1504], "text": "Small Methods 2024, 8, 2301283", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["footer label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["footer label"], "span_metadata": [{"size": 6.973800182342529, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 56, "page": 23, "raw_label": "footer", "text": "Small Methods 2024, 8, 2301283", "bbox": [99, 1488, 288, 1504], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "Small Methods 2024, 8, 2301283"}, "layout_signature": {"width": 189, "width_bucket": 200, "height": 16, "left": 99, "top": 1488, "right": 288, "bottom": 1504, "x_center": 193.5, "x_center_bucket": 200, "y_center": 1496.0, "x_ratio": 0.1625, "y_ratio": 0.9559, "width_ratio": 0.1587, "height_ratio": 0.0102, "line_count": 1}, "span_signature": {"font_size": 6.97, "font_size_median": 6.97, "font_size_bucket": 7.0, "font_family_norm": "ScalaSansPro-Italic", "bold": true, "italic": true, "span_count": 5}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_127", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 23, "block_id": 57, "raw_label": "footer", "raw_order": null, "bbox": [527, 1485, 668, 1507], "text": "2301283 (23 of 27)", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.9, "evidence": ["footer label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["footer label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaSansPro-Bold", "flags": 20, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 57, "page": 23, "raw_label": "footer", "text": "2301283 (23 of 27)", "bbox": [527, 1485, 668, 1507], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_dot", "raw_marker": "2301283", "number": 2301283, "kind": "reference", "normalized_text": "2301283 (23 of 27)"}, "layout_signature": {"width": 141, "width_bucket": 150, "height": 22, "left": 527, "top": 1485, "right": 668, "bottom": 1507, "x_center": 597.5, "x_center_bucket": 600, "y_center": 1496.0, "x_ratio": 0.5017, "y_ratio": 0.9559, "width_ratio": 0.1184, "height_ratio": 0.0141, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaSansPro-Bold", "bold": true, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_family_anchor", "reading_band_id": "band_127", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 23, "block_id": 58, "raw_label": "footer", "raw_order": null, "bbox": [938, 1487, 1096, 1505], "text": "© 2024 Wiley-VCH GmbH", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["footer label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["footer label"], "span_metadata": [{"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 58, "page": 23, "raw_label": "footer", "text": "© 2024 Wiley-VCH GmbH", "bbox": [938, 1487, 1096, 1505], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "© 2024 Wiley-VCH GmbH"}, "layout_signature": {"width": 158, "width_bucket": 150, "height": 18, "left": 938, "top": 1487, "right": 1096, "bottom": 1505, "x_center": 1017.0, "x_center_bucket": 1025, "y_center": 1496.0, "x_ratio": 0.8539, "y_ratio": 0.9559, "width_ratio": 0.1327, "height_ratio": 0.0115, "line_count": 1}, "span_signature": {"font_size": 6.97, "font_size_median": 6.97, "font_size_bucket": 7.0, "font_family_norm": "ScalaSansPro-Regular", "bold": false, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_127", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 23, "block_id": 59, "raw_label": "aside_text", "raw_order": null, "bbox": [1155, 32, 1171, 1535], "text": "23699608, 2024, 8, Downloaded from https://onlinelibrary.wiley.com/doi/10.1002/smll.202301283 by Shandong University Library, Wiley Online Library on [18/02/2026]. See the Terms and Conditions (https://onlinelibrary.wiley.com/terms-and-conditions) on Wiley Online Library for rules of use; OA articles are governed by the applicable Creative Commons License.", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.95, "evidence": ["margin-band narrow/tall geometry; treated as noise"], "seed_role": "noise", "seed_confidence": 0.95, "seed_evidence": ["margin-band narrow/tall geometry; treated as noise"], "span_metadata": [{"size": 5.03000020980835, "font": "Times-Roman", "flags": 4, "color": 0, "dir": [0.0, 1.0], "wmode": 0}], "raw_observation": {"block_id": 59, "page": 23, "raw_label": "aside_text", "text": "23699608, 2024, 8, Downloaded from https://onlinelibrary.wiley.com/doi/10.1002/smll.202301283 by Shandong University Library, Wiley Online Library on [18/02/2026]. See the Terms and Conditions (https://onlinelibrary.wiley.com/terms-and-conditions) on Wiley Online Library for rules of use; OA articles are governed by the applicable Creative Commons License.", "bbox": [1155, 32, 1171, 1535], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "23699608, 2024, 8, Downloaded from https://onlinelibrary.wiley.com/doi/10.1002/smll.202301283 by Shandong University Library, Wiley Online Library on [18/02/2026]. See the Terms and Conditions (https://onlinelibrary.wiley.com/terms-and-conditions) on Wiley Online Library for rules of use; OA articles are governed by the applicable Creative Commons License."}, "layout_signature": {"width": 16, "width_bucket": 25, "height": 1503, "left": 1155, "top": 32, "right": 1171, "bottom": 1535, "x_center": 1163.0, "x_center_bucket": 1175, "y_center": 783.5, "x_ratio": 0.9765, "y_ratio": 0.5006, "width_ratio": 0.0134, "height_ratio": 0.9604, "line_count": 1}, "span_signature": {"font_size": 5.03, "font_size_median": 5.03, "font_size_bucket": 5.0, "font_family_norm": "Times-Roman", "bold": false, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_127", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 24, "block_id": 0, "raw_label": "header", "raw_order": null, "bbox": [92, 46, 338, 116], "text": "ADVANCED\nSCIENCE NEWS\nwww.advancedsciencenews.com", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["header label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["header label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaSansPro-Bold", "flags": 20, "color": 255, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 0, "page": 24, "raw_label": "header", "text": "ADVANCED\nSCIENCE NEWS\nwww.advancedsciencenews.com", "bbox": [92, 46, 338, 116], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "ADVANCED\nSCIENCE NEWS\nwww.advancedsciencenews.com"}, "layout_signature": {"width": 246, "width_bucket": 250, "height": 70, "left": 92, "top": 46, "right": 338, "bottom": 116, "x_center": 215.0, "x_center_bucket": 225, "y_center": 81.0, "x_ratio": 0.1805, "y_ratio": 0.0518, "width_ratio": 0.2065, "height_ratio": 0.0447, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaSansPro-Bold", "bold": true, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 24, "block_id": 1, "raw_label": "header", "raw_order": null, "bbox": [997, 36, 1089, 95], "text": "small methods", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["header label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["header label"], "span_metadata": null, "raw_observation": {"block_id": 1, "page": 24, "raw_label": "header", "text": "small methods", "bbox": [997, 36, 1089, 95], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "short_fragment", "raw_marker": "small methods", "number": null, "kind": "short_fragment", "normalized_text": "small methods"}, "layout_signature": {"width": 92, "width_bucket": 100, "height": 59, "left": 997, "top": 36, "right": 1089, "bottom": 95, "x_center": 1043.0, "x_center_bucket": 1050, "y_center": 65.5, "x_ratio": 0.8757, "y_ratio": 0.0419, "width_ratio": 0.0772, "height_ratio": 0.0377, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": true, "_container_bbox": [1000.0802235557833, 37.836628863963085, 1078.3616835103696, 91.04600210547972], "_container_text": "small methods", "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_142", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.6, "decision": "structured_insert_candidate", "evidence": ["visual_container", "narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 24, "block_id": 2, "raw_label": "header", "raw_order": null, "bbox": [897, 98, 1090, 116], "text": "www.small-methods.com", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["header label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["header label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaSansPro-Bold", "flags": 20, "color": 255, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 2, "page": 24, "raw_label": "header", "text": "www.small-methods.com", "bbox": [897, 98, 1090, 116], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "www.small-methods.com"}, "layout_signature": {"width": 193, "width_bucket": 200, "height": 18, "left": 897, "top": 98, "right": 1090, "bottom": 116, "x_center": 993.5, "x_center_bucket": 1000, "y_center": 107.0, "x_ratio": 0.8342, "y_ratio": 0.0684, "width_ratio": 0.162, "height_ratio": 0.0115, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaSansPro-Bold", "bold": true, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_142", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 24, "block_id": 3, "raw_label": "reference_content", "raw_order": 1, "bbox": [100, 150, 581, 189], "text": "[45] K. Zheng, J. Wu, W. Li, D. Dippold, Y. Wan, A. R. Boccaccini, ACS Biomater. Sci. Eng. 2018, 4, 1546.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [45] K. Zheng, J. Wu, W. Li, D. Dippold, Y. Wan, A. R. Bocca"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [45] K. Zheng, J. Wu, W. Li, D. Dippold, Y. Wan, A. R. Bocca"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 3, "page": 24, "raw_label": "reference_content", "text": "[45] K. Zheng, J. Wu, W. Li, D. Dippold, Y. Wan, A. R. Boccaccini, ACS Biomater. Sci. Eng. 2018, 4, 1546.", "bbox": [100, 150, 581, 189], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[45]", "number": 45, "kind": "reference", "normalized_text": "[45] K. Zheng, J. Wu, W. Li, D. Dippold, Y. Wan, A. R. Boccaccini, ACS Biomater. Sci. Eng. 2018, 4, 1546."}, "layout_signature": {"width": 481, "width_bucket": 475, "height": 39, "left": 100, "top": 150, "right": 581, "bottom": 189, "x_center": 340.5, "x_center_bucket": 350, "y_center": 169.5, "x_ratio": 0.2859, "y_ratio": 0.1083, "width_ratio": 0.4039, "height_ratio": 0.0249, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 34}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_139", "display_cluster_candidate_id": "disp_27_0", "layout_region": "display_zone", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 24, "block_id": 4, "raw_label": "reference_content", "raw_order": 2, "bbox": [101, 191, 580, 229], "text": "[46] L. Weng, S. K. Boda, M. J. Teusink, F. D. Shuler, X. Li, J. Xie, ACS Appl. Mater. Interfaces 2017, 9, 24484.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [46] L. Weng, S. K. Boda, M. J. Teusink, F. D. Shuler, X. Li"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [46] L. Weng, S. K. Boda, M. J. Teusink, F. D. Shuler, X. Li"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 4, "page": 24, "raw_label": "reference_content", "text": "[46] L. Weng, S. K. Boda, M. J. Teusink, F. D. Shuler, X. Li, J. Xie, ACS Appl. Mater. Interfaces 2017, 9, 24484.", "bbox": [101, 191, 580, 229], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[46]", "number": 46, "kind": "reference", "normalized_text": "[46] L. Weng, S. K. Boda, M. J. Teusink, F. D. Shuler, X. Li, J. Xie, ACS Appl. Mater. Interfaces 2017, 9, 24484."}, "layout_signature": {"width": 479, "width_bucket": 475, "height": 38, "left": 101, "top": 191, "right": 580, "bottom": 229, "x_center": 340.5, "x_center_bucket": 350, "y_center": 210.0, "x_ratio": 0.2859, "y_ratio": 0.1342, "width_ratio": 0.4022, "height_ratio": 0.0243, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 38}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_140", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 24, "block_id": 5, "raw_label": "reference_content", "raw_order": 3, "bbox": [101, 231, 581, 269], "text": "[47] S. Kargozar, F. Baino, S. Hamzehlou, R. G. Hill, M. Mozafari, Trends Biotechnol. 2018, 36, 430.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [47] S. Kargozar, F. Baino, S. Hamzehlou, R. G. Hill, M. Moz"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [47] S. Kargozar, F. Baino, S. Hamzehlou, R. G. Hill, M. Moz"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 5, "page": 24, "raw_label": "reference_content", "text": "[47] S. Kargozar, F. Baino, S. Hamzehlou, R. G. Hill, M. Mozafari, Trends Biotechnol. 2018, 36, 430.", "bbox": [101, 231, 581, 269], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[47]", "number": 47, "kind": "reference", "normalized_text": "[47] S. Kargozar, F. Baino, S. Hamzehlou, R. G. Hill, M. Mozafari, Trends Biotechnol. 2018, 36, 430."}, "layout_signature": {"width": 480, "width_bucket": 475, "height": 38, "left": 101, "top": 231, "right": 581, "bottom": 269, "x_center": 341.0, "x_center_bucket": 350, "y_center": 250.0, "x_ratio": 0.2863, "y_ratio": 0.1597, "width_ratio": 0.403, "height_ratio": 0.0243, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 9}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_139", "display_cluster_candidate_id": "disp_27_0", "layout_region": "display_zone", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 24, "block_id": 6, "raw_label": "reference_content", "raw_order": 4, "bbox": [101, 271, 580, 328], "text": "[48] A. Bari, N. Bloise, S. Fiorilli, G. Novajra, M. Vallet-Regi, G. Bruni, A. Torres-Pardo, J. M. González-Calbet, L. Visai, C. Vitale-Brovarone, Acta Biomater. 2017, 55, 493.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [48] A. Bari, N. Bloise, S. Fiorilli, G. Novajra, M. Vallet-"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [48] A. Bari, N. Bloise, S. Fiorilli, G. Novajra, M. Vallet-"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 6, "page": 24, "raw_label": "reference_content", "text": "[48] A. Bari, N. Bloise, S. Fiorilli, G. Novajra, M. Vallet-Regi, G. Bruni, A. Torres-Pardo, J. M. González-Calbet, L. Visai, C. Vitale-Brovarone, Acta Biomater. 2017, 55, 493.", "bbox": [101, 271, 580, 328], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[48]", "number": 48, "kind": "reference", "normalized_text": "[48] A. Bari, N. Bloise, S. Fiorilli, G. Novajra, M. Vallet-Regi, G. Bruni, A. Torres-Pardo, J. M. González-Calbet, L. Visai, C. Vitale-Brovarone, Acta Biomater. 2017, 55, 493."}, "layout_signature": {"width": 479, "width_bucket": 475, "height": 57, "left": 101, "top": 271, "right": 580, "bottom": 328, "x_center": 340.5, "x_center_bucket": 350, "y_center": 299.5, "x_ratio": 0.2859, "y_ratio": 0.1914, "width_ratio": 0.4022, "height_ratio": 0.0364, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 23}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_140", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 24, "block_id": 7, "raw_label": "reference_content", "raw_order": 5, "bbox": [101, 331, 579, 388], "text": "[49] Q. Nawaz, M A Ur Rehman, A. Burkovski, J. Schmidt, A. M. Beltrán, A. Shahid, N. K. Alber, W. Peukert, A. R. Boccaccini, J. Mater. Sci. Mater. Med. 2018, 29, 64.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [49] Q. Nawaz, M A Ur Rehman, A. Burkovski, J. Schmidt, A. M"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [49] Q. Nawaz, M A Ur Rehman, A. Burkovski, J. Schmidt, A. M"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 7, "page": 24, "raw_label": "reference_content", "text": "[49] Q. Nawaz, M A Ur Rehman, A. Burkovski, J. Schmidt, A. M. Beltrán, A. Shahid, N. K. Alber, W. Peukert, A. R. Boccaccini, J. Mater. Sci. Mater. Med. 2018, 29, 64.", "bbox": [101, 331, 579, 388], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[49]", "number": 49, "kind": "reference", "normalized_text": "[49] Q. Nawaz, M A Ur Rehman, A. Burkovski, J. Schmidt, A. M. Beltrán, A. Shahid, N. K. Alber, W. Peukert, A. R. Boccaccini, J. Mater. Sci. Mater. Med. 2018, 29, 64."}, "layout_signature": {"width": 478, "width_bucket": 475, "height": 57, "left": 101, "top": 331, "right": 579, "bottom": 388, "x_center": 340.0, "x_center_bucket": 350, "y_center": 359.5, "x_ratio": 0.2855, "y_ratio": 0.2297, "width_ratio": 0.4013, "height_ratio": 0.0364, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 33}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_139", "display_cluster_candidate_id": "disp_27_0", "layout_region": "display_zone", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 24, "block_id": 8, "raw_label": "reference_content", "raw_order": 6, "bbox": [101, 391, 580, 427], "text": "[50] S. Kaya, M. Cresswell, A. R. Boccaccini, Mater. Sci. Eng., C 2018, 83, 99.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [50] S. Kaya, M. Cresswell, A. R. Boccaccini, Mater. Sci. En"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [50] S. Kaya, M. Cresswell, A. R. Boccaccini, Mater. Sci. En"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 8, "page": 24, "raw_label": "reference_content", "text": "[50] S. Kaya, M. Cresswell, A. R. Boccaccini, Mater. Sci. Eng., C 2018, 83, 99.", "bbox": [101, 391, 580, 427], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[50]", "number": 50, "kind": "reference", "normalized_text": "[50] S. Kaya, M. Cresswell, A. R. Boccaccini, Mater. Sci. Eng., C 2018, 83, 99."}, "layout_signature": {"width": 479, "width_bucket": 475, "height": 36, "left": 101, "top": 391, "right": 580, "bottom": 427, "x_center": 340.5, "x_center_bucket": 350, "y_center": 409.0, "x_ratio": 0.2859, "y_ratio": 0.2613, "width_ratio": 0.4022, "height_ratio": 0.023, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 9}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_140", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 24, "block_id": 9, "raw_label": "reference_content", "raw_order": 7, "bbox": [102, 430, 581, 468], "text": "[51] N. Ramesh, S. C. Moratti, G. J. Dias, J. Biomed. Mater. Res. Part B Appl. Biomater. 2018, 106, 2046.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [51] N. Ramesh, S. C. Moratti, G. J. Dias, J. Biomed. Mater."], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [51] N. Ramesh, S. C. Moratti, G. J. Dias, J. Biomed. Mater."], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 9, "page": 24, "raw_label": "reference_content", "text": "[51] N. Ramesh, S. C. Moratti, G. J. Dias, J. Biomed. Mater. Res. Part B Appl. Biomater. 2018, 106, 2046.", "bbox": [102, 430, 581, 468], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[51]", "number": 51, "kind": "reference", "normalized_text": "[51] N. Ramesh, S. C. Moratti, G. J. Dias, J. Biomed. Mater. Res. Part B Appl. Biomater. 2018, 106, 2046."}, "layout_signature": {"width": 479, "width_bucket": 475, "height": 38, "left": 102, "top": 430, "right": 581, "bottom": 468, "x_center": 341.5, "x_center_bucket": 350, "y_center": 449.0, "x_ratio": 0.2867, "y_ratio": 0.2869, "width_ratio": 0.4022, "height_ratio": 0.0243, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 34}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_138", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 24, "block_id": 10, "raw_label": "reference_content", "raw_order": 8, "bbox": [102, 470, 528, 489], "text": "[52] M. Müller, Macromol. Rapid Commun. 2019, 40, 1900151.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [52] M. Müller, Macromol. Rapid Commun. 2019, 40, 1900151."], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [52] M. Müller, Macromol. Rapid Commun. 2019, 40, 1900151."], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 10, "page": 24, "raw_label": "reference_content", "text": "[52] M. Müller, Macromol. Rapid Commun. 2019, 40, 1900151.", "bbox": [102, 470, 528, 489], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[52]", "number": 52, "kind": "reference", "normalized_text": "[52] M. Müller, Macromol. Rapid Commun. 2019, 40, 1900151."}, "layout_signature": {"width": 426, "width_bucket": 425, "height": 19, "left": 102, "top": 470, "right": 528, "bottom": 489, "x_center": 315.0, "x_center_bucket": 325, "y_center": 479.5, "x_ratio": 0.2645, "y_ratio": 0.3064, "width_ratio": 0.3577, "height_ratio": 0.0121, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 8}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_141", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "hard", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 24, "block_id": 11, "raw_label": "reference_content", "raw_order": 9, "bbox": [102, 490, 579, 528], "text": "[53] M. Filippi, G. Born, M. Chaaban, A. Scherberich, Front. Bioeng. Biotechnol. 2020, 8.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [53] M. Filippi, G. Born, M. Chaaban, A. Scherberich, Front."], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [53] M. Filippi, G. Born, M. Chaaban, A. Scherberich, Front."], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 11, "page": 24, "raw_label": "reference_content", "text": "[53] M. Filippi, G. Born, M. Chaaban, A. Scherberich, Front. Bioeng. Biotechnol. 2020, 8.", "bbox": [102, 490, 579, 528], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[53]", "number": 53, "kind": "reference", "normalized_text": "[53] M. Filippi, G. Born, M. Chaaban, A. Scherberich, Front. Bioeng. Biotechnol. 2020, 8."}, "layout_signature": {"width": 477, "width_bucket": 475, "height": 38, "left": 102, "top": 490, "right": 579, "bottom": 528, "x_center": 340.5, "x_center_bucket": 350, "y_center": 509.0, "x_ratio": 0.2859, "y_ratio": 0.3252, "width_ratio": 0.4005, "height_ratio": 0.0243, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 26}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_142", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 24, "block_id": 12, "raw_label": "reference_content", "raw_order": 10, "bbox": [101, 530, 579, 568], "text": "[54] F. Cheng, Y. Wu, H. Li, T. Yan, X. Wei, G. Wu, J. He, Y. Huang, Carbohydr. Polym. 2019, 207, 180.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [54] F. Cheng, Y. Wu, H. Li, T. Yan, X. Wei, G. Wu, J. He, Y"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [54] F. Cheng, Y. Wu, H. Li, T. Yan, X. Wei, G. Wu, J. He, Y"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 12, "page": 24, "raw_label": "reference_content", "text": "[54] F. Cheng, Y. Wu, H. Li, T. Yan, X. Wei, G. Wu, J. He, Y. Huang, Carbohydr. Polym. 2019, 207, 180.", "bbox": [101, 530, 579, 568], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[54]", "number": 54, "kind": "reference", "normalized_text": "[54] F. Cheng, Y. Wu, H. Li, T. Yan, X. Wei, G. Wu, J. He, Y. Huang, Carbohydr. Polym. 2019, 207, 180."}, "layout_signature": {"width": 478, "width_bucket": 475, "height": 38, "left": 101, "top": 530, "right": 579, "bottom": 568, "x_center": 340.0, "x_center_bucket": 350, "y_center": 549.0, "x_ratio": 0.2855, "y_ratio": 0.3508, "width_ratio": 0.4013, "height_ratio": 0.0243, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 9}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_142", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 24, "block_id": 13, "raw_label": "reference_content", "raw_order": 11, "bbox": [102, 570, 578, 608], "text": "[55] F. Tao, Y. Cheng, X. Shi, H. Zheng, Y. Du, W. Xiang, H. Deng, Carbohydr. Polym. 2020, 230, 115658.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [55] F. Tao, Y. Cheng, X. Shi, H. Zheng, Y. Du, W. Xiang, H."], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [55] F. Tao, Y. Cheng, X. Shi, H. Zheng, Y. Du, W. Xiang, H."], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 13, "page": 24, "raw_label": "reference_content", "text": "[55] F. Tao, Y. Cheng, X. Shi, H. Zheng, Y. Du, W. Xiang, H. Deng, Carbohydr. Polym. 2020, 230, 115658.", "bbox": [102, 570, 578, 608], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[55]", "number": 55, "kind": "reference", "normalized_text": "[55] F. Tao, Y. Cheng, X. Shi, H. Zheng, Y. Du, W. Xiang, H. Deng, Carbohydr. Polym. 2020, 230, 115658."}, "layout_signature": {"width": 476, "width_bucket": 475, "height": 38, "left": 102, "top": 570, "right": 578, "bottom": 608, "x_center": 340.0, "x_center_bucket": 350, "y_center": 589.0, "x_ratio": 0.2855, "y_ratio": 0.3764, "width_ratio": 0.3997, "height_ratio": 0.0243, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 9}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_136", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 24, "block_id": 14, "raw_label": "reference_content", "raw_order": 12, "bbox": [101, 610, 579, 648], "text": "[56] M. Fathi, M. Alami-Milani, M. H. Geranmayeh, J. Barar, H. Erfan-Niya, Y. Omidi, Int. J. Biol. Macromol. 2019, 128, 957.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [56] M. Fathi, M. Alami-Milani, M. H. Geranmayeh, J. Barar, "], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [56] M. Fathi, M. Alami-Milani, M. H. Geranmayeh, J. Barar, "], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 14, "page": 24, "raw_label": "reference_content", "text": "[56] M. Fathi, M. Alami-Milani, M. H. Geranmayeh, J. Barar, H. Erfan-Niya, Y. Omidi, Int. J. Biol. Macromol. 2019, 128, 957.", "bbox": [101, 610, 579, 648], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[56]", "number": 56, "kind": "reference", "normalized_text": "[56] M. Fathi, M. Alami-Milani, M. H. Geranmayeh, J. Barar, H. Erfan-Niya, Y. Omidi, Int. J. Biol. Macromol. 2019, 128, 957."}, "layout_signature": {"width": 478, "width_bucket": 475, "height": 38, "left": 101, "top": 610, "right": 579, "bottom": 648, "x_center": 340.0, "x_center_bucket": 350, "y_center": 629.0, "x_ratio": 0.2855, "y_ratio": 0.4019, "width_ratio": 0.4013, "height_ratio": 0.0243, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 29}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_136", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 24, "block_id": 15, "raw_label": "reference_content", "raw_order": 13, "bbox": [102, 650, 579, 688], "text": "[57] Y. Lei, Z. Xu, Q. Ke, W. Yin, Y. Chen, C. Zhang, Y. Guo, Mater. Sci. Eng. C Mater. Biol. Appl. 2017, 72, 134.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [57] Y. Lei, Z. Xu, Q. Ke, W. Yin, Y. Chen, C. Zhang, Y. Guo"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [57] Y. Lei, Z. Xu, Q. Ke, W. Yin, Y. Chen, C. Zhang, Y. Guo"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 15, "page": 24, "raw_label": "reference_content", "text": "[57] Y. Lei, Z. Xu, Q. Ke, W. Yin, Y. Chen, C. Zhang, Y. Guo, Mater. Sci. Eng. C Mater. Biol. Appl. 2017, 72, 134.", "bbox": [102, 650, 579, 688], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[57]", "number": 57, "kind": "reference", "normalized_text": "[57] Y. Lei, Z. Xu, Q. Ke, W. Yin, Y. Chen, C. Zhang, Y. Guo, Mater. Sci. Eng. C Mater. Biol. Appl. 2017, 72, 134."}, "layout_signature": {"width": 477, "width_bucket": 475, "height": 38, "left": 102, "top": 650, "right": 579, "bottom": 688, "x_center": 340.5, "x_center_bucket": 350, "y_center": 669.0, "x_ratio": 0.2859, "y_ratio": 0.4275, "width_ratio": 0.4005, "height_ratio": 0.0243, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 38}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_136", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 24, "block_id": 16, "raw_label": "reference_content", "raw_order": 14, "bbox": [102, 689, 540, 708], "text": "[58] Y. He, W. Wang, X. Tang, X. Liu, Dent. Mater. J. 2017, 36, 325.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [58] Y. He, W. Wang, X. Tang, X. Liu, Dent. Mater. J. 2017, "], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [58] Y. He, W. Wang, X. Tang, X. Liu, Dent. Mater. J. 2017, "], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 16, "page": 24, "raw_label": "reference_content", "text": "[58] Y. He, W. Wang, X. Tang, X. Liu, Dent. Mater. J. 2017, 36, 325.", "bbox": [102, 689, 540, 708], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[58]", "number": 58, "kind": "reference", "normalized_text": "[58] Y. He, W. Wang, X. Tang, X. Liu, Dent. Mater. J. 2017, 36, 325."}, "layout_signature": {"width": 438, "width_bucket": 450, "height": 19, "left": 102, "top": 689, "right": 540, "bottom": 708, "x_center": 321.0, "x_center_bucket": 325, "y_center": 698.5, "x_ratio": 0.2695, "y_ratio": 0.4463, "width_ratio": 0.3678, "height_ratio": 0.0121, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 8}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_136", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 24, "block_id": 17, "raw_label": "reference_content", "raw_order": 15, "bbox": [102, 709, 580, 731], "text": "[59] K. Jahan, M. Mekhail, M. Tabrizian, Carbohydr. Polym. 2019, 203, 60.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [59] K. Jahan, M. Mekhail, M. Tabrizian, Carbohydr. Polym. 2"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [59] K. Jahan, M. Mekhail, M. Tabrizian, Carbohydr. Polym. 2"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 17, "page": 24, "raw_label": "reference_content", "text": "[59] K. Jahan, M. Mekhail, M. Tabrizian, Carbohydr. Polym. 2019, 203, 60.", "bbox": [102, 709, 580, 731], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[59]", "number": 59, "kind": "reference", "normalized_text": "[59] K. Jahan, M. Mekhail, M. Tabrizian, Carbohydr. Polym. 2019, 203, 60."}, "layout_signature": {"width": 478, "width_bucket": 475, "height": 22, "left": 102, "top": 709, "right": 580, "bottom": 731, "x_center": 341.0, "x_center_bucket": 350, "y_center": 720.0, "x_ratio": 0.2863, "y_ratio": 0.4601, "width_ratio": 0.4013, "height_ratio": 0.0141, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 8}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_136", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 24, "block_id": 18, "raw_label": "reference_content", "raw_order": 16, "bbox": [102, 729, 481, 748], "text": "[60] D. Zhong, Z. Du, M. Zhou, View 2021, 2, 20200189.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [60] D. Zhong, Z. Du, M. Zhou, View 2021, 2, 20200189."], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [60] D. Zhong, Z. Du, M. Zhou, View 2021, 2, 20200189."], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 18, "page": 24, "raw_label": "reference_content", "text": "[60] D. Zhong, Z. Du, M. Zhou, View 2021, 2, 20200189.", "bbox": [102, 729, 481, 748], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[60]", "number": 60, "kind": "reference", "normalized_text": "[60] D. Zhong, Z. Du, M. Zhou, View 2021, 2, 20200189."}, "layout_signature": {"width": 379, "width_bucket": 375, "height": 19, "left": 102, "top": 729, "right": 481, "bottom": 748, "x_center": 291.5, "x_center_bucket": 300, "y_center": 738.5, "x_ratio": 0.2448, "y_ratio": 0.4719, "width_ratio": 0.3182, "height_ratio": 0.0121, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 8}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_136", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 24, "block_id": 19, "raw_label": "reference_content", "raw_order": 17, "bbox": [102, 749, 579, 787], "text": "[61] G. Sharmila, C. Muthukumaran, S. Kirthika, S. Keerthana, N. M. Kumar, J. Jeyanthi, Int. J. Biol. Macromol. 2020, 156, 430.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [61] G. Sharmila, C. Muthukumaran, S. Kirthika, S. Keerthana"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [61] G. Sharmila, C. Muthukumaran, S. Kirthika, S. Keerthana"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 19, "page": 24, "raw_label": "reference_content", "text": "[61] G. Sharmila, C. Muthukumaran, S. Kirthika, S. Keerthana, N. M. Kumar, J. Jeyanthi, Int. J. Biol. Macromol. 2020, 156, 430.", "bbox": [102, 749, 579, 787], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[61]", "number": 61, "kind": "reference", "normalized_text": "[61] G. Sharmila, C. Muthukumaran, S. Kirthika, S. Keerthana, N. M. Kumar, J. Jeyanthi, Int. J. Biol. Macromol. 2020, 156, 430."}, "layout_signature": {"width": 477, "width_bucket": 475, "height": 38, "left": 102, "top": 749, "right": 579, "bottom": 787, "x_center": 340.5, "x_center_bucket": 350, "y_center": 768.0, "x_ratio": 0.2859, "y_ratio": 0.4907, "width_ratio": 0.4005, "height_ratio": 0.0243, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 27}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_136", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 24, "block_id": 20, "raw_label": "reference_content", "raw_order": 18, "bbox": [102, 789, 580, 827], "text": "[62] A. C. Hernández-González, L. Téllez-Jurado, L. M. Rodríguez-Lorenzo, Carbohydr. Polym. 2020, 229, 115514.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [62] A. C. Hernández-González, L. Téllez-Jurado, L. M. Rodrí"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [62] A. C. Hernández-González, L. Téllez-Jurado, L. M. Rodrí"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 20, "page": 24, "raw_label": "reference_content", "text": "[62] A. C. Hernández-González, L. Téllez-Jurado, L. M. Rodríguez-Lorenzo, Carbohydr. Polym. 2020, 229, 115514.", "bbox": [102, 789, 580, 827], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[62]", "number": 62, "kind": "reference", "normalized_text": "[62] A. C. Hernández-González, L. Téllez-Jurado, L. M. Rodríguez-Lorenzo, Carbohydr. Polym. 2020, 229, 115514."}, "layout_signature": {"width": 478, "width_bucket": 475, "height": 38, "left": 102, "top": 789, "right": 580, "bottom": 827, "x_center": 341.0, "x_center_bucket": 350, "y_center": 808.0, "x_ratio": 0.2863, "y_ratio": 0.5163, "width_ratio": 0.4013, "height_ratio": 0.0243, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 23}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_136", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 24, "block_id": 21, "raw_label": "reference_content", "raw_order": 19, "bbox": [101, 828, 580, 866], "text": "[63] Z. Luo, Y. Yang, Yi Deng, Y. Sun, H. Yang, S. Wei, Colloids Surf., B 2016, 143, 243.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [63] Z. Luo, Y. Yang, Yi Deng, Y. Sun, H. Yang, S. Wei, Coll"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [63] Z. Luo, Y. Yang, Yi Deng, Y. Sun, H. Yang, S. Wei, Coll"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 21, "page": 24, "raw_label": "reference_content", "text": "[63] Z. Luo, Y. Yang, Yi Deng, Y. Sun, H. Yang, S. Wei, Colloids Surf., B 2016, 143, 243.", "bbox": [101, 828, 580, 866], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[63]", "number": 63, "kind": "reference", "normalized_text": "[63] Z. Luo, Y. Yang, Yi Deng, Y. Sun, H. Yang, S. Wei, Colloids Surf., B 2016, 143, 243."}, "layout_signature": {"width": 479, "width_bucket": 475, "height": 38, "left": 101, "top": 828, "right": 580, "bottom": 866, "x_center": 340.5, "x_center_bucket": 350, "y_center": 847.0, "x_ratio": 0.2859, "y_ratio": 0.5412, "width_ratio": 0.4022, "height_ratio": 0.0243, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 35}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_133", "display_cluster_candidate_id": "disp_26_0", "layout_region": "display_zone", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 24, "block_id": 22, "raw_label": "reference_content", "raw_order": 20, "bbox": [102, 869, 580, 908], "text": "[64] X. Fang, L. Lei, T. Jiang, Y. Chen, Y. Kang, J. Biomed. Mater. Res. B Appl. Biomater. 2018, 106, 1739.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [64] X. Fang, L. Lei, T. Jiang, Y. Chen, Y. Kang, J. Biomed."], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [64] X. Fang, L. Lei, T. Jiang, Y. Chen, Y. Kang, J. Biomed."], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 22, "page": 24, "raw_label": "reference_content", "text": "[64] X. Fang, L. Lei, T. Jiang, Y. Chen, Y. Kang, J. Biomed. Mater. Res. B Appl. Biomater. 2018, 106, 1739.", "bbox": [102, 869, 580, 908], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[64]", "number": 64, "kind": "reference", "normalized_text": "[64] X. Fang, L. Lei, T. Jiang, Y. Chen, Y. Kang, J. Biomed. Mater. Res. B Appl. Biomater. 2018, 106, 1739."}, "layout_signature": {"width": 478, "width_bucket": 475, "height": 39, "left": 102, "top": 869, "right": 580, "bottom": 908, "x_center": 341.0, "x_center_bucket": 350, "y_center": 888.5, "x_ratio": 0.2863, "y_ratio": 0.5677, "width_ratio": 0.4013, "height_ratio": 0.0249, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 36}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_134", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 24, "block_id": 23, "raw_label": "reference_content", "raw_order": 21, "bbox": [102, 909, 579, 946], "text": "[65] P. Zhai, X. Peng, B. Li, Y. Liu, H. Sun, X. Li, Int. J. Biol. Macromol. 2020, 151, 1224.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [65] P. Zhai, X. Peng, B. Li, Y. Liu, H. Sun, X. Li, Int. J."], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [65] P. Zhai, X. Peng, B. Li, Y. Liu, H. Sun, X. Li, Int. J."], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 23, "page": 24, "raw_label": "reference_content", "text": "[65] P. Zhai, X. Peng, B. Li, Y. Liu, H. Sun, X. Li, Int. J. Biol. Macromol. 2020, 151, 1224.", "bbox": [102, 909, 579, 946], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[65]", "number": 65, "kind": "reference", "normalized_text": "[65] P. Zhai, X. Peng, B. Li, Y. Liu, H. Sun, X. Li, Int. J. Biol. Macromol. 2020, 151, 1224."}, "layout_signature": {"width": 477, "width_bucket": 475, "height": 37, "left": 102, "top": 909, "right": 579, "bottom": 946, "x_center": 340.5, "x_center_bucket": 350, "y_center": 927.5, "x_ratio": 0.2859, "y_ratio": 0.5927, "width_ratio": 0.4005, "height_ratio": 0.0236, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 37}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_133", "display_cluster_candidate_id": "disp_26_0", "layout_region": "display_zone", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 24, "block_id": 24, "raw_label": "reference_content", "raw_order": 22, "bbox": [102, 949, 581, 986], "text": "[66] G. Abatangelo, V. Vindigni, G. Avruscio, L. Pandis, P. Brun, Cells 2020, 9, 1743.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [66] G. Abatangelo, V. Vindigni, G. Avruscio, L. Pandis, P. "], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [66] G. Abatangelo, V. Vindigni, G. Avruscio, L. Pandis, P. "], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 24, "page": 24, "raw_label": "reference_content", "text": "[66] G. Abatangelo, V. Vindigni, G. Avruscio, L. Pandis, P. Brun, Cells 2020, 9, 1743.", "bbox": [102, 949, 581, 986], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[66]", "number": 66, "kind": "reference", "normalized_text": "[66] G. Abatangelo, V. Vindigni, G. Avruscio, L. Pandis, P. Brun, Cells 2020, 9, 1743."}, "layout_signature": {"width": 479, "width_bucket": 475, "height": 37, "left": 102, "top": 949, "right": 581, "bottom": 986, "x_center": 341.5, "x_center_bucket": 350, "y_center": 967.5, "x_ratio": 0.2867, "y_ratio": 0.6182, "width_ratio": 0.4022, "height_ratio": 0.0236, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 27}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_134", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 24, "block_id": 25, "raw_label": "reference_content", "raw_order": 23, "bbox": [102, 988, 579, 1025], "text": "[67] J.-W. Kim, Y.-S. Han, H.-M. Lee, J.-K. Kim, Y.-J. Kim, Int. J. Mol. Sci. 2021, 22, 6794.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [67] J.-W. Kim, Y.-S. Han, H.-M. Lee, J.-K. Kim, Y.-J. Kim, "], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [67] J.-W. Kim, Y.-S. Han, H.-M. Lee, J.-K. Kim, Y.-J. Kim, "], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 25, "page": 24, "raw_label": "reference_content", "text": "[67] J.-W. Kim, Y.-S. Han, H.-M. Lee, J.-K. Kim, Y.-J. Kim, Int. J. Mol. Sci. 2021, 22, 6794.", "bbox": [102, 988, 579, 1025], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[67]", "number": 67, "kind": "reference", "normalized_text": "[67] J.-W. Kim, Y.-S. Han, H.-M. Lee, J.-K. Kim, Y.-J. Kim, Int. J. Mol. Sci. 2021, 22, 6794."}, "layout_signature": {"width": 477, "width_bucket": 475, "height": 37, "left": 102, "top": 988, "right": 579, "bottom": 1025, "x_center": 340.5, "x_center_bucket": 350, "y_center": 1006.5, "x_ratio": 0.2859, "y_ratio": 0.6431, "width_ratio": 0.4005, "height_ratio": 0.0236, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 8}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_131", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 24, "block_id": 26, "raw_label": "reference_content", "raw_order": 24, "bbox": [102, 1027, 579, 1085], "text": "[68] Xu Cui, C. Huang, Z. Chen, M. Zhang, C. Liu, K. Su, J. Wang, Li Li, R. Wang, B. Li, D. Chen, C. Ruan, D. Wang, W. W. Lu, H. Pan, Bioact. Mater. 2021, 6, 3801.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [68] Xu Cui, C. Huang, Z. Chen, M. Zhang, C. Liu, K. Su, J. "], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [68] Xu Cui, C. Huang, Z. Chen, M. Zhang, C. Liu, K. Su, J. "], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 26, "page": 24, "raw_label": "reference_content", "text": "[68] Xu Cui, C. Huang, Z. Chen, M. Zhang, C. Liu, K. Su, J. Wang, Li Li, R. Wang, B. Li, D. Chen, C. Ruan, D. Wang, W. W. Lu, H. Pan, Bioact. Mater. 2021, 6, 3801.", "bbox": [102, 1027, 579, 1085], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[68]", "number": 68, "kind": "reference", "normalized_text": "[68] Xu Cui, C. Huang, Z. Chen, M. Zhang, C. Liu, K. Su, J. Wang, Li Li, R. Wang, B. Li, D. Chen, C. Ruan, D. Wang, W. W. Lu, H. Pan, Bioact. Mater. 2021, 6, 3801."}, "layout_signature": {"width": 477, "width_bucket": 475, "height": 58, "left": 102, "top": 1027, "right": 579, "bottom": 1085, "x_center": 340.5, "x_center_bucket": 350, "y_center": 1056.0, "x_ratio": 0.2859, "y_ratio": 0.6748, "width_ratio": 0.4005, "height_ratio": 0.0371, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 10}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_135", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "hard", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 24, "block_id": 27, "raw_label": "reference_content", "raw_order": 25, "bbox": [102, 1088, 578, 1145], "text": "[69] M. R. Todeschi, R. M. El Backly, O. P. Varghese, J. Hilborn, R. Cancedda, M. Mastrogiacomo, Regener. Med. 2017, 12, 525.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [69] M. R. Todeschi, R. M. El Backly, O. P. Varghese, J. Hil"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [69] M. R. Todeschi, R. M. El Backly, O. P. Varghese, J. Hil"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 27, "page": 24, "raw_label": "reference_content", "text": "[69] M. R. Todeschi, R. M. El Backly, O. P. Varghese, J. Hilborn, R. Cancedda, M. Mastrogiacomo, Regener. Med. 2017, 12, 525.", "bbox": [102, 1088, 578, 1145], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[69]", "number": 69, "kind": "reference", "normalized_text": "[69] M. R. Todeschi, R. M. El Backly, O. P. Varghese, J. Hilborn, R. Cancedda, M. Mastrogiacomo, Regener. Med. 2017, 12, 525."}, "layout_signature": {"width": 476, "width_bucket": 475, "height": 57, "left": 102, "top": 1088, "right": 578, "bottom": 1145, "x_center": 340.0, "x_center_bucket": 350, "y_center": 1116.5, "x_ratio": 0.2855, "y_ratio": 0.7134, "width_ratio": 0.3997, "height_ratio": 0.0364, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 43}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_137", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 24, "block_id": 28, "raw_label": "reference_content", "raw_order": 26, "bbox": [102, 1148, 579, 1186], "text": "[70] S. Preethi Soundarya, A. Haritha Menon, S. Viji Chandran, N. Selvamurugan, Int. J. Biol. Macromol. 2018, 119, 1228.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [70] S. Preethi Soundarya, A. Haritha Menon, S. Viji Chandra"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [70] S. Preethi Soundarya, A. Haritha Menon, S. Viji Chandra"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 28, "page": 24, "raw_label": "reference_content", "text": "[70] S. Preethi Soundarya, A. Haritha Menon, S. Viji Chandran, N. Selvamurugan, Int. J. Biol. Macromol. 2018, 119, 1228.", "bbox": [102, 1148, 579, 1186], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[70]", "number": 70, "kind": "reference", "normalized_text": "[70] S. Preethi Soundarya, A. Haritha Menon, S. Viji Chandran, N. Selvamurugan, Int. J. Biol. Macromol. 2018, 119, 1228."}, "layout_signature": {"width": 477, "width_bucket": 475, "height": 38, "left": 102, "top": 1148, "right": 579, "bottom": 1186, "x_center": 340.5, "x_center_bucket": 350, "y_center": 1167.0, "x_ratio": 0.2859, "y_ratio": 0.7457, "width_ratio": 0.4005, "height_ratio": 0.0243, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 27}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_137", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 24, "block_id": 29, "raw_label": "reference_content", "raw_order": 27, "bbox": [102, 1188, 580, 1225], "text": "[71] D. N. Heo, M. Hospodiuk, I. T. Ozbolat, Acta Biomater. 2019, 95, 348.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [71] D. N. Heo, M. Hospodiuk, I. T. Ozbolat, Acta Biomater. "], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [71] D. N. Heo, M. Hospodiuk, I. T. Ozbolat, Acta Biomater. "], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 29, "page": 24, "raw_label": "reference_content", "text": "[71] D. N. Heo, M. Hospodiuk, I. T. Ozbolat, Acta Biomater. 2019, 95, 348.", "bbox": [102, 1188, 580, 1225], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[71]", "number": 71, "kind": "reference", "normalized_text": "[71] D. N. Heo, M. Hospodiuk, I. T. Ozbolat, Acta Biomater. 2019, 95, 348."}, "layout_signature": {"width": 478, "width_bucket": 475, "height": 37, "left": 102, "top": 1188, "right": 580, "bottom": 1225, "x_center": 341.0, "x_center_bucket": 350, "y_center": 1206.5, "x_ratio": 0.2863, "y_ratio": 0.7709, "width_ratio": 0.4013, "height_ratio": 0.0236, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 28}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_126", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 24, "block_id": 30, "raw_label": "reference_content", "raw_order": 28, "bbox": [102, 1227, 535, 1246], "text": "[72] Y. Chen, N. Kawazoe, G. Chen, Acta Biomater. 2018, 67, 341.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [72] Y. Chen, N. Kawazoe, G. Chen, Acta Biomater. 2018, 67, "], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [72] Y. Chen, N. Kawazoe, G. Chen, Acta Biomater. 2018, 67, "], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 30, "page": 24, "raw_label": "reference_content", "text": "[72] Y. Chen, N. Kawazoe, G. Chen, Acta Biomater. 2018, 67, 341.", "bbox": [102, 1227, 535, 1246], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[72]", "number": 72, "kind": "reference", "normalized_text": "[72] Y. Chen, N. Kawazoe, G. Chen, Acta Biomater. 2018, 67, 341."}, "layout_signature": {"width": 433, "width_bucket": 425, "height": 19, "left": 102, "top": 1227, "right": 535, "bottom": 1246, "x_center": 318.5, "x_center_bucket": 325, "y_center": 1236.5, "x_ratio": 0.2674, "y_ratio": 0.7901, "width_ratio": 0.3636, "height_ratio": 0.0121, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 8}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_126", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 24, "block_id": 31, "raw_label": "reference_content", "raw_order": 29, "bbox": [102, 1247, 513, 1266], "text": "[73] M. Mahmoudi Saber, Colloids Surf., B 2019, 183, 110407.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [73] M. Mahmoudi Saber, Colloids Surf., B 2019, 183, 110407."], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [73] M. Mahmoudi Saber, Colloids Surf., B 2019, 183, 110407."], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 31, "page": 24, "raw_label": "reference_content", "text": "[73] M. Mahmoudi Saber, Colloids Surf., B 2019, 183, 110407.", "bbox": [102, 1247, 513, 1266], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[73]", "number": 73, "kind": "reference", "normalized_text": "[73] M. Mahmoudi Saber, Colloids Surf., B 2019, 183, 110407."}, "layout_signature": {"width": 411, "width_bucket": 400, "height": 19, "left": 102, "top": 1247, "right": 513, "bottom": 1266, "x_center": 307.5, "x_center_bucket": 300, "y_center": 1256.5, "x_ratio": 0.2582, "y_ratio": 0.8029, "width_ratio": 0.3451, "height_ratio": 0.0121, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 8}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_126", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 24, "block_id": 32, "raw_label": "reference_content", "raw_order": 30, "bbox": [102, 1267, 579, 1305], "text": "[74] T. T. Hoang Thi, J. S. Lee, Y. Lee, K. M. Park, Ki D Park, Macromol. Biosci. 2016, 16, 334.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [74] T. T. Hoang Thi, J. S. Lee, Y. Lee, K. M. Park, Ki D Pa"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [74] T. T. Hoang Thi, J. S. Lee, Y. Lee, K. M. Park, Ki D Pa"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 32, "page": 24, "raw_label": "reference_content", "text": "[74] T. T. Hoang Thi, J. S. Lee, Y. Lee, K. M. Park, Ki D Park, Macromol. Biosci. 2016, 16, 334.", "bbox": [102, 1267, 579, 1305], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[74]", "number": 74, "kind": "reference", "normalized_text": "[74] T. T. Hoang Thi, J. S. Lee, Y. Lee, K. M. Park, Ki D Park, Macromol. Biosci. 2016, 16, 334."}, "layout_signature": {"width": 477, "width_bucket": 475, "height": 38, "left": 102, "top": 1267, "right": 579, "bottom": 1305, "x_center": 340.5, "x_center_bucket": 350, "y_center": 1286.0, "x_ratio": 0.2859, "y_ratio": 0.8217, "width_ratio": 0.4005, "height_ratio": 0.0243, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 27}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_126", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 24, "block_id": 33, "raw_label": "reference_content", "raw_order": 31, "bbox": [101, 1307, 578, 1364], "text": "[75] X. Zhou, J. Sun, K. Wo, H. Wei, H. Lei, J. Zhang, X. Lu, F. Mei, Q. Tang, Y. Wang, Z. Luo, L. Fan, Y. Chu, L. Chen, Carbohydr. Polym. 2022, 298, 120127.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [75] X. Zhou, J. Sun, K. Wo, H. Wei, H. Lei, J. Zhang, X. Lu"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [75] X. Zhou, J. Sun, K. Wo, H. Wei, H. Lei, J. Zhang, X. Lu"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 33, "page": 24, "raw_label": "reference_content", "text": "[75] X. Zhou, J. Sun, K. Wo, H. Wei, H. Lei, J. Zhang, X. Lu, F. Mei, Q. Tang, Y. Wang, Z. Luo, L. Fan, Y. Chu, L. Chen, Carbohydr. Polym. 2022, 298, 120127.", "bbox": [101, 1307, 578, 1364], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[75]", "number": 75, "kind": "reference", "normalized_text": "[75] X. Zhou, J. Sun, K. Wo, H. Wei, H. Lei, J. Zhang, X. Lu, F. Mei, Q. Tang, Y. Wang, Z. Luo, L. Fan, Y. Chu, L. Chen, Carbohydr. Polym. 2022, 298, 120127."}, "layout_signature": {"width": 477, "width_bucket": 475, "height": 57, "left": 101, "top": 1307, "right": 578, "bottom": 1364, "x_center": 339.5, "x_center_bucket": 350, "y_center": 1335.5, "x_ratio": 0.2851, "y_ratio": 0.8534, "width_ratio": 0.4005, "height_ratio": 0.0364, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 64}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_126", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 24, "block_id": 34, "raw_label": "reference_content", "raw_order": 32, "bbox": [101, 1367, 578, 1404], "text": "[76] S. Dasgupta, K. Maji, S. K. Nandi, Mater. Sci. Eng. C Mater. Biol. Appl. 2019, 94, 713.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [76] S. Dasgupta, K. Maji, S. K. Nandi, Mater. Sci. Eng. C M"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [76] S. Dasgupta, K. Maji, S. K. Nandi, Mater. Sci. Eng. C M"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 34, "page": 24, "raw_label": "reference_content", "text": "[76] S. Dasgupta, K. Maji, S. K. Nandi, Mater. Sci. Eng. C Mater. Biol. Appl. 2019, 94, 713.", "bbox": [101, 1367, 578, 1404], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[76]", "number": 76, "kind": "reference", "normalized_text": "[76] S. Dasgupta, K. Maji, S. K. Nandi, Mater. Sci. Eng. C Mater. Biol. Appl. 2019, 94, 713."}, "layout_signature": {"width": 477, "width_bucket": 475, "height": 37, "left": 101, "top": 1367, "right": 578, "bottom": 1404, "x_center": 339.5, "x_center_bucket": 350, "y_center": 1385.5, "x_ratio": 0.2851, "y_ratio": 0.8853, "width_ratio": 0.4005, "height_ratio": 0.0236, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 8}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_124", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 24, "block_id": 35, "raw_label": "reference_content", "raw_order": 33, "bbox": [102, 1407, 542, 1426], "text": "[77] A. Thomas, J. Bera, J. Biomater. Sci., Polym. Ed. 2019, 30, 561.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [77] A. Thomas, J. Bera, J. Biomater. Sci., Polym. Ed. 2019,"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [77] A. Thomas, J. Bera, J. Biomater. Sci., Polym. Ed. 2019,"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 35, "page": 24, "raw_label": "reference_content", "text": "[77] A. Thomas, J. Bera, J. Biomater. Sci., Polym. Ed. 2019, 30, 561.", "bbox": [102, 1407, 542, 1426], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[77]", "number": 77, "kind": "reference", "normalized_text": "[77] A. Thomas, J. Bera, J. Biomater. Sci., Polym. Ed. 2019, 30, 561."}, "layout_signature": {"width": 440, "width_bucket": 450, "height": 19, "left": 102, "top": 1407, "right": 542, "bottom": 1426, "x_center": 322.0, "x_center_bucket": 325, "y_center": 1416.5, "x_ratio": 0.2704, "y_ratio": 0.9051, "width_ratio": 0.3694, "height_ratio": 0.0121, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 8}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_127", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 24, "block_id": 36, "raw_label": "reference_content", "raw_order": 34, "bbox": [611, 151, 1090, 209], "text": "[78] M. C. Echave, R. Hernáez-Moya, L. Iturriaga, J. L. Pedraz, R. Lakshminarayanan, A. Dolatshahi-Pirouz, N. Taebnia, G. Orive, Expert Opin. Biol. Ther. 2019, 19, 773.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [78] M. C. Echave, R. Hernáez-Moya, L. Iturriaga, J. L. Pedr"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [78] M. C. Echave, R. Hernáez-Moya, L. Iturriaga, J. L. Pedr"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 36, "page": 24, "raw_label": "reference_content", "text": "[78] M. C. Echave, R. Hernáez-Moya, L. Iturriaga, J. L. Pedraz, R. Lakshminarayanan, A. Dolatshahi-Pirouz, N. Taebnia, G. Orive, Expert Opin. Biol. Ther. 2019, 19, 773.", "bbox": [611, 151, 1090, 209], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[78]", "number": 78, "kind": "reference", "normalized_text": "[78] M. C. Echave, R. Hernáez-Moya, L. Iturriaga, J. L. Pedraz, R. Lakshminarayanan, A. Dolatshahi-Pirouz, N. Taebnia, G. Orive, Expert Opin. Biol. Ther. 2019, 19, 773."}, "layout_signature": {"width": 479, "width_bucket": 475, "height": 58, "left": 611, "top": 151, "right": 1090, "bottom": 209, "x_center": 850.5, "x_center_bucket": 850, "y_center": 180.0, "x_ratio": 0.7141, "y_ratio": 0.115, "width_ratio": 0.4022, "height_ratio": 0.0371, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 30}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_127", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 24, "block_id": 37, "raw_label": "reference_content", "raw_order": 35, "bbox": [611, 211, 1090, 249], "text": "[79] M. Farokhi, F. Mottaghitalab, Y. Fatahi, A. Khademhosseini, D. L. Kaplan, Trends Biotechnol. 2018, 36, 907.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [79] M. Farokhi, F. Mottaghitalab, Y. Fatahi, A. Khademhosse"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [79] M. Farokhi, F. Mottaghitalab, Y. Fatahi, A. Khademhosse"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 37, "page": 24, "raw_label": "reference_content", "text": "[79] M. Farokhi, F. Mottaghitalab, Y. Fatahi, A. Khademhosseini, D. L. Kaplan, Trends Biotechnol. 2018, 36, 907.", "bbox": [611, 211, 1090, 249], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[79]", "number": 79, "kind": "reference", "normalized_text": "[79] M. Farokhi, F. Mottaghitalab, Y. Fatahi, A. Khademhosseini, D. L. Kaplan, Trends Biotechnol. 2018, 36, 907."}, "layout_signature": {"width": 479, "width_bucket": 475, "height": 38, "left": 611, "top": 211, "right": 1090, "bottom": 249, "x_center": 850.5, "x_center_bucket": 850, "y_center": 230.0, "x_ratio": 0.7141, "y_ratio": 0.147, "width_ratio": 0.4022, "height_ratio": 0.0243, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 27}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_127", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 24, "block_id": 38, "raw_label": "reference_content", "raw_order": 36, "bbox": [613, 251, 1089, 288], "text": "[80] Yi Zhou, X. Liu, H. She, R. Wang, F. Bai, B. Xiang, Regen. Ther. 2022, 21, 307.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [80] Yi Zhou, X. Liu, H. She, R. Wang, F. Bai, B. Xiang, Reg"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [80] Yi Zhou, X. Liu, H. She, R. Wang, F. Bai, B. Xiang, Reg"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 38, "page": 24, "raw_label": "reference_content", "text": "[80] Yi Zhou, X. Liu, H. She, R. Wang, F. Bai, B. Xiang, Regen. Ther. 2022, 21, 307.", "bbox": [613, 251, 1089, 288], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[80]", "number": 80, "kind": "reference", "normalized_text": "[80] Yi Zhou, X. Liu, H. She, R. Wang, F. Bai, B. Xiang, Regen. Ther. 2022, 21, 307."}, "layout_signature": {"width": 476, "width_bucket": 475, "height": 37, "left": 613, "top": 251, "right": 1089, "bottom": 288, "x_center": 851.0, "x_center_bucket": 850, "y_center": 269.5, "x_ratio": 0.7145, "y_ratio": 0.1722, "width_ratio": 0.3997, "height_ratio": 0.0236, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 8}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_127", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 24, "block_id": 39, "raw_label": "reference_content", "raw_order": 37, "bbox": [613, 290, 1089, 329], "text": "[81] X. Du, D. Wei, Li Huang, M. Zhu, Y. Zhang, Y. Zhu, Mater. Sci. Eng. C Mater. Biol. Appl. 2019, 103, 109731.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [81] X. Du, D. Wei, Li Huang, M. Zhu, Y. Zhang, Y. Zhu, Mate"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [81] X. Du, D. Wei, Li Huang, M. Zhu, Y. Zhang, Y. Zhu, Mate"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 39, "page": 24, "raw_label": "reference_content", "text": "[81] X. Du, D. Wei, Li Huang, M. Zhu, Y. Zhang, Y. Zhu, Mater. Sci. Eng. C Mater. Biol. Appl. 2019, 103, 109731.", "bbox": [613, 290, 1089, 329], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[81]", "number": 81, "kind": "reference", "normalized_text": "[81] X. Du, D. Wei, Li Huang, M. Zhu, Y. Zhang, Y. Zhu, Mater. Sci. Eng. C Mater. Biol. Appl. 2019, 103, 109731."}, "layout_signature": {"width": 476, "width_bucket": 475, "height": 39, "left": 613, "top": 290, "right": 1089, "bottom": 329, "x_center": 851.0, "x_center_bucket": 850, "y_center": 309.5, "x_ratio": 0.7145, "y_ratio": 0.1978, "width_ratio": 0.3997, "height_ratio": 0.0249, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 9}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_127", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 24, "block_id": 40, "raw_label": "reference_content", "raw_order": 38, "bbox": [612, 331, 1091, 368], "text": "[82] D. Mao, Q. Li, D. Li, Y. Chen, X. Chen, Xi Xu, Mater. Design 2018, 142, 1.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [82] D. Mao, Q. Li, D. Li, Y. Chen, X. Chen, Xi Xu, Mater. D"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [82] D. Mao, Q. Li, D. Li, Y. Chen, X. Chen, Xi Xu, Mater. D"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 40, "page": 24, "raw_label": "reference_content", "text": "[82] D. Mao, Q. Li, D. Li, Y. Chen, X. Chen, Xi Xu, Mater. Design 2018, 142, 1.", "bbox": [612, 331, 1091, 368], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[82]", "number": 82, "kind": "reference", "normalized_text": "[82] D. Mao, Q. Li, D. Li, Y. Chen, X. Chen, Xi Xu, Mater. Design 2018, 142, 1."}, "layout_signature": {"width": 479, "width_bucket": 475, "height": 37, "left": 612, "top": 331, "right": 1091, "bottom": 368, "x_center": 851.5, "x_center_bucket": 850, "y_center": 349.5, "x_ratio": 0.7149, "y_ratio": 0.2233, "width_ratio": 0.4022, "height_ratio": 0.0236, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 34}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_127", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 24, "block_id": 41, "raw_label": "reference_content", "raw_order": 39, "bbox": [612, 371, 1090, 427], "text": "[83] A. Gregor, E. Filová, M. Novák, J. Kronek, H. Chlup, M. Buzgo, V. Blahnová, V. Lukášová, M. Bartos, A. Necas, J. Hosek, J. Biol. Eng. 2017, 11, 31.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [83] A. Gregor, E. Filová, M. Novák, J. Kronek, H. Chlup, M."], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [83] A. Gregor, E. Filová, M. Novák, J. Kronek, H. Chlup, M."], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 41, "page": 24, "raw_label": "reference_content", "text": "[83] A. Gregor, E. Filová, M. Novák, J. Kronek, H. Chlup, M. Buzgo, V. Blahnová, V. Lukášová, M. Bartos, A. Necas, J. Hosek, J. Biol. Eng. 2017, 11, 31.", "bbox": [612, 371, 1090, 427], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[83]", "number": 83, "kind": "reference", "normalized_text": "[83] A. Gregor, E. Filová, M. Novák, J. Kronek, H. Chlup, M. Buzgo, V. Blahnová, V. Lukášová, M. Bartos, A. Necas, J. Hosek, J. Biol. Eng. 2017, 11, 31."}, "layout_signature": {"width": 478, "width_bucket": 475, "height": 56, "left": 612, "top": 371, "right": 1090, "bottom": 427, "x_center": 851.0, "x_center_bucket": 850, "y_center": 399.0, "x_ratio": 0.7145, "y_ratio": 0.255, "width_ratio": 0.4013, "height_ratio": 0.0358, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 54}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_127", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 24, "block_id": 42, "raw_label": "reference_content", "raw_order": 40, "bbox": [612, 430, 1089, 487], "text": "[84] A. Grémare, V. Guduric, R. Bareille, V. Heroguez, S. Latour, N. L'heureux, J.-C. Fricain, S. Catros, D. Le Nihouannen, J. Biomed. Mater. Res., Part A 2018, 106, 887.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [84] A. Grémare, V. Guduric, R. Bareille, V. Heroguez, S. La"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [84] A. Grémare, V. Guduric, R. Bareille, V. Heroguez, S. La"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 42, "page": 24, "raw_label": "reference_content", "text": "[84] A. Grémare, V. Guduric, R. Bareille, V. Heroguez, S. Latour, N. L'heureux, J.-C. Fricain, S. Catros, D. Le Nihouannen, J. Biomed. Mater. Res., Part A 2018, 106, 887.", "bbox": [612, 430, 1089, 487], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[84]", "number": 84, "kind": "reference", "normalized_text": "[84] A. Grémare, V. Guduric, R. Bareille, V. Heroguez, S. Latour, N. L'heureux, J.-C. Fricain, S. Catros, D. Le Nihouannen, J. Biomed. Mater. Res., Part A 2018, 106, 887."}, "layout_signature": {"width": 477, "width_bucket": 475, "height": 57, "left": 612, "top": 430, "right": 1089, "bottom": 487, "x_center": 850.5, "x_center_bucket": 850, "y_center": 458.5, "x_ratio": 0.7141, "y_ratio": 0.293, "width_ratio": 0.4005, "height_ratio": 0.0364, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 47}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_127", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 24, "block_id": 43, "raw_label": "reference_content", "raw_order": 41, "bbox": [612, 490, 1091, 528], "text": "[85] B. Holmes, K. Bulusu, M. Plesniak, L. G. Zhang, Nanotechnology 2016, 27, 064001.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [85] B. Holmes, K. Bulusu, M. Plesniak, L. G. Zhang, Nanotec"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [85] B. Holmes, K. Bulusu, M. Plesniak, L. G. Zhang, Nanotec"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 43, "page": 24, "raw_label": "reference_content", "text": "[85] B. Holmes, K. Bulusu, M. Plesniak, L. G. Zhang, Nanotechnology 2016, 27, 064001.", "bbox": [612, 490, 1091, 528], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[85]", "number": 85, "kind": "reference", "normalized_text": "[85] B. Holmes, K. Bulusu, M. Plesniak, L. G. Zhang, Nanotechnology 2016, 27, 064001."}, "layout_signature": {"width": 479, "width_bucket": 475, "height": 38, "left": 612, "top": 490, "right": 1091, "bottom": 528, "x_center": 851.5, "x_center_bucket": 850, "y_center": 509.0, "x_ratio": 0.7149, "y_ratio": 0.3252, "width_ratio": 0.4022, "height_ratio": 0.0243, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 25}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_127", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 24, "block_id": 44, "raw_label": "reference_content", "raw_order": 42, "bbox": [612, 530, 1091, 568], "text": "[86] Z. Ren, S. Ma, Le Jin, Z. Liu, D. Liu, Xu Zhang, Q. Cai, X. Yang, Bio-fabrication 2017, 9, 025036.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [86] Z. Ren, S. Ma, Le Jin, Z. Liu, D. Liu, Xu Zhang, Q. Cai"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [86] Z. Ren, S. Ma, Le Jin, Z. Liu, D. Liu, Xu Zhang, Q. Cai"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 44, "page": 24, "raw_label": "reference_content", "text": "[86] Z. Ren, S. Ma, Le Jin, Z. Liu, D. Liu, Xu Zhang, Q. Cai, X. Yang, Bio-fabrication 2017, 9, 025036.", "bbox": [612, 530, 1091, 568], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[86]", "number": 86, "kind": "reference", "normalized_text": "[86] Z. Ren, S. Ma, Le Jin, Z. Liu, D. Liu, Xu Zhang, Q. Cai, X. Yang, Bio-fabrication 2017, 9, 025036."}, "layout_signature": {"width": 479, "width_bucket": 475, "height": 38, "left": 612, "top": 530, "right": 1091, "bottom": 568, "x_center": 851.5, "x_center_bucket": 850, "y_center": 549.0, "x_ratio": 0.7149, "y_ratio": 0.3508, "width_ratio": 0.4022, "height_ratio": 0.0243, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 9}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_127", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 24, "block_id": 45, "raw_label": "reference_content", "raw_order": 43, "bbox": [613, 570, 1090, 626], "text": "[87] J. Meng, F. Boschetto, S. Yagi, E. Marin, T. Adachi, X. Chen, G. Pezzotti, S. Sakurai, H. Yamane, H. Xu, Mater. Design 2022, 219, 110781.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [87] J. Meng, F. Boschetto, S. Yagi, E. Marin, T. Adachi, X."], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [87] J. Meng, F. Boschetto, S. Yagi, E. Marin, T. Adachi, X."], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 45, "page": 24, "raw_label": "reference_content", "text": "[87] J. Meng, F. Boschetto, S. Yagi, E. Marin, T. Adachi, X. Chen, G. Pezzotti, S. Sakurai, H. Yamane, H. Xu, Mater. Design 2022, 219, 110781.", "bbox": [613, 570, 1090, 626], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[87]", "number": 87, "kind": "reference", "normalized_text": "[87] J. Meng, F. Boschetto, S. Yagi, E. Marin, T. Adachi, X. Chen, G. Pezzotti, S. Sakurai, H. Yamane, H. Xu, Mater. Design 2022, 219, 110781."}, "layout_signature": {"width": 477, "width_bucket": 475, "height": 56, "left": 613, "top": 570, "right": 1090, "bottom": 626, "x_center": 851.5, "x_center_bucket": 850, "y_center": 598.0, "x_ratio": 0.7149, "y_ratio": 0.3821, "width_ratio": 0.4005, "height_ratio": 0.0358, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 51}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_127", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 24, "block_id": 46, "raw_label": "reference_content", "raw_order": 44, "bbox": [612, 629, 938, 648], "text": "[88] O. Janousková, Physiol. Res. 2018, 67, S335.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [88] O. Janousková, Physiol. Res. 2018, 67, S335."], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [88] O. Janousková, Physiol. Res. 2018, 67, S335."], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 46, "page": 24, "raw_label": "reference_content", "text": "[88] O. Janousková, Physiol. Res. 2018, 67, S335.", "bbox": [612, 629, 938, 648], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[88]", "number": 88, "kind": "reference", "normalized_text": "[88] O. Janousková, Physiol. Res. 2018, 67, S335."}, "layout_signature": {"width": 326, "width_bucket": 325, "height": 19, "left": 612, "top": 629, "right": 938, "bottom": 648, "x_center": 775.0, "x_center_bucket": 775, "y_center": 638.5, "x_ratio": 0.6507, "y_ratio": 0.408, "width_ratio": 0.2737, "height_ratio": 0.0121, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 8}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_127", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 24, "block_id": 47, "raw_label": "reference_content", "raw_order": 45, "bbox": [613, 650, 1090, 688], "text": "[89] F. Asghari, M. Samiei, K. Adibkia, A. Akbarzadeh, S. Davaran, Artif. Cell Nanomed. B 2017, 45, 185.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [89] F. Asghari, M. Samiei, K. Adibkia, A. Akbarzadeh, S. Da"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [89] F. Asghari, M. Samiei, K. Adibkia, A. Akbarzadeh, S. Da"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 47, "page": 24, "raw_label": "reference_content", "text": "[89] F. Asghari, M. Samiei, K. Adibkia, A. Akbarzadeh, S. Davaran, Artif. Cell Nanomed. B 2017, 45, 185.", "bbox": [613, 650, 1090, 688], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[89]", "number": 89, "kind": "reference", "normalized_text": "[89] F. Asghari, M. Samiei, K. Adibkia, A. Akbarzadeh, S. Davaran, Artif. Cell Nanomed. B 2017, 45, 185."}, "layout_signature": {"width": 477, "width_bucket": 475, "height": 38, "left": 613, "top": 650, "right": 1090, "bottom": 688, "x_center": 851.5, "x_center_bucket": 850, "y_center": 669.0, "x_ratio": 0.7149, "y_ratio": 0.4275, "width_ratio": 0.4005, "height_ratio": 0.0243, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 9}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_127", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 24, "block_id": 48, "raw_label": "reference_content", "raw_order": 46, "bbox": [613, 689, 1090, 708], "text": "[90] T. Ding, W. Kang, J. Li, Lu Yu, S. Ge, J. Nanobiotechnol. 2021, 19, 247.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [90] T. Ding, W. Kang, J. Li, Lu Yu, S. Ge, J. Nanobiotechno"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [90] T. Ding, W. Kang, J. Li, Lu Yu, S. Ge, J. Nanobiotechno"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 48, "page": 24, "raw_label": "reference_content", "text": "[90] T. Ding, W. Kang, J. Li, Lu Yu, S. Ge, J. Nanobiotechnol. 2021, 19, 247.", "bbox": [613, 689, 1090, 708], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[90]", "number": 90, "kind": "reference", "normalized_text": "[90] T. Ding, W. Kang, J. Li, Lu Yu, S. Ge, J. Nanobiotechnol. 2021, 19, 247."}, "layout_signature": {"width": 477, "width_bucket": 475, "height": 19, "left": 613, "top": 689, "right": 1090, "bottom": 708, "x_center": 851.5, "x_center_bucket": 850, "y_center": 698.5, "x_ratio": 0.7149, "y_ratio": 0.4463, "width_ratio": 0.4005, "height_ratio": 0.0121, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 8}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_127", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 24, "block_id": 49, "raw_label": "reference_content", "raw_order": 47, "bbox": [613, 709, 1090, 747], "text": "[91] X. Zhao, Yu Han, J. Li, Bo Cai, H. Gao, W. Feng, S. Li, J. Liu, D. Li, Mater. Sci. Eng. C Mater. Biol. Appl. 2017, 78, 658.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [91] X. Zhao, Yu Han, J. Li, Bo Cai, H. Gao, W. Feng, S. Li,"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [91] X. Zhao, Yu Han, J. Li, Bo Cai, H. Gao, W. Feng, S. Li,"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 49, "page": 24, "raw_label": "reference_content", "text": "[91] X. Zhao, Yu Han, J. Li, Bo Cai, H. Gao, W. Feng, S. Li, J. Liu, D. Li, Mater. Sci. Eng. C Mater. Biol. Appl. 2017, 78, 658.", "bbox": [613, 709, 1090, 747], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[91]", "number": 91, "kind": "reference", "normalized_text": "[91] X. Zhao, Yu Han, J. Li, Bo Cai, H. Gao, W. Feng, S. Li, J. Liu, D. Li, Mater. Sci. Eng. C Mater. Biol. Appl. 2017, 78, 658."}, "layout_signature": {"width": 477, "width_bucket": 475, "height": 38, "left": 613, "top": 709, "right": 1090, "bottom": 747, "x_center": 851.5, "x_center_bucket": 850, "y_center": 728.0, "x_ratio": 0.7149, "y_ratio": 0.4652, "width_ratio": 0.4005, "height_ratio": 0.0243, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 8}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_126", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 24, "block_id": 50, "raw_label": "reference_content", "raw_order": 48, "bbox": [613, 750, 1090, 807], "text": "[92] J. Babilotte, B. Martin, V. Guduric, R. Bareille, R. Agniel, S. Roques, V. Héroguez, M. Dussauze, M. Gaudon, D. Le Nihouannen, S. Catros, Mater. Sci. Eng. C Mater. Biol. Appl. 2021, 118, 111334.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [92] J. Babilotte, B. Martin, V. Guduric, R. Bareille, R. Ag"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [92] J. Babilotte, B. Martin, V. Guduric, R. Bareille, R. Ag"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 50, "page": 24, "raw_label": "reference_content", "text": "[92] J. Babilotte, B. Martin, V. Guduric, R. Bareille, R. Agniel, S. Roques, V. Héroguez, M. Dussauze, M. Gaudon, D. Le Nihouannen, S. Catros, Mater. Sci. Eng. C Mater. Biol. Appl. 2021, 118, 111334.", "bbox": [613, 750, 1090, 807], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[92]", "number": 92, "kind": "reference", "normalized_text": "[92] J. Babilotte, B. Martin, V. Guduric, R. Bareille, R. Agniel, S. Roques, V. Héroguez, M. Dussauze, M. Gaudon, D. Le Nihouannen, S. Catros, Mater. Sci. Eng. C Mater. Biol. Appl. 2021, 118, 111334."}, "layout_signature": {"width": 477, "width_bucket": 475, "height": 57, "left": 613, "top": 750, "right": 1090, "bottom": 807, "x_center": 851.5, "x_center_bucket": 850, "y_center": 778.5, "x_ratio": 0.7149, "y_ratio": 0.4974, "width_ratio": 0.4005, "height_ratio": 0.0364, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 9}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_127", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 24, "block_id": 51, "raw_label": "reference_content", "raw_order": 49, "bbox": [613, 809, 1089, 847], "text": "[93] Y. Boukari, O. Qutachi, D. J. Scurr, A. P. Morris, S. W. Doughty, N. Billa, J. Biomater. Sci., Polym. Ed. 2017, 28, 1966,", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [93] Y. Boukari, O. Qutachi, D. J. Scurr, A. P. Morris, S. W"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [93] Y. Boukari, O. Qutachi, D. J. Scurr, A. P. Morris, S. W"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 51, "page": 24, "raw_label": "reference_content", "text": "[93] Y. Boukari, O. Qutachi, D. J. Scurr, A. P. Morris, S. W. Doughty, N. Billa, J. Biomater. Sci., Polym. Ed. 2017, 28, 1966,", "bbox": [613, 809, 1089, 847], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[93]", "number": 93, "kind": "reference", "normalized_text": "[93] Y. Boukari, O. Qutachi, D. J. Scurr, A. P. Morris, S. W. Doughty, N. Billa, J. Biomater. Sci., Polym. Ed. 2017, 28, 1966,"}, "layout_signature": {"width": 476, "width_bucket": 475, "height": 38, "left": 613, "top": 809, "right": 1089, "bottom": 847, "x_center": 851.0, "x_center_bucket": 850, "y_center": 828.0, "x_ratio": 0.7145, "y_ratio": 0.5291, "width_ratio": 0.3997, "height_ratio": 0.0243, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 9}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_127", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 24, "block_id": 52, "raw_label": "reference_content", "raw_order": 50, "bbox": [613, 850, 1090, 886], "text": "[94] W.-C. Lin, C. Yao, T.-Y. Huang, S.-J. Cheng, C.-M. Tang, Dent. Mater. 2019, 35, 751.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [94] W.-C. Lin, C. Yao, T.-Y. Huang, S.-J. Cheng, C.-M. Tang"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [94] W.-C. Lin, C. Yao, T.-Y. Huang, S.-J. Cheng, C.-M. Tang"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 52, "page": 24, "raw_label": "reference_content", "text": "[94] W.-C. Lin, C. Yao, T.-Y. Huang, S.-J. Cheng, C.-M. Tang, Dent. Mater. 2019, 35, 751.", "bbox": [613, 850, 1090, 886], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[94]", "number": 94, "kind": "reference", "normalized_text": "[94] W.-C. Lin, C. Yao, T.-Y. Huang, S.-J. Cheng, C.-M. Tang, Dent. Mater. 2019, 35, 751."}, "layout_signature": {"width": 477, "width_bucket": 475, "height": 36, "left": 613, "top": 850, "right": 1090, "bottom": 886, "x_center": 851.5, "x_center_bucket": 850, "y_center": 868.0, "x_ratio": 0.7149, "y_ratio": 0.5546, "width_ratio": 0.4005, "height_ratio": 0.023, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 8}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_127", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 24, "block_id": 53, "raw_label": "reference_content", "raw_order": 51, "bbox": [613, 889, 1090, 947], "text": "[95] A. B. Faia-Torres, M. Charnley, T. Goren, S. Guimond-Lischer, M. Rottmar, K. Maniura-Weber, N. D. Spencer, R. L. Reis, M. Textor, N. M. Neves, Acta Biomater. 2015, 28, 64.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [95] A. B. Faia-Torres, M. Charnley, T. Goren, S. Guimond-Li"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [95] A. B. Faia-Torres, M. Charnley, T. Goren, S. Guimond-Li"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 53, "page": 24, "raw_label": "reference_content", "text": "[95] A. B. Faia-Torres, M. Charnley, T. Goren, S. Guimond-Lischer, M. Rottmar, K. Maniura-Weber, N. D. Spencer, R. L. Reis, M. Textor, N. M. Neves, Acta Biomater. 2015, 28, 64.", "bbox": [613, 889, 1090, 947], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[95]", "number": 95, "kind": "reference", "normalized_text": "[95] A. B. Faia-Torres, M. Charnley, T. Goren, S. Guimond-Lischer, M. Rottmar, K. Maniura-Weber, N. D. Spencer, R. L. Reis, M. Textor, N. M. Neves, Acta Biomater. 2015, 28, 64."}, "layout_signature": {"width": 477, "width_bucket": 475, "height": 58, "left": 613, "top": 889, "right": 1090, "bottom": 947, "x_center": 851.5, "x_center_bucket": 850, "y_center": 918.0, "x_ratio": 0.7149, "y_ratio": 0.5866, "width_ratio": 0.4005, "height_ratio": 0.0371, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 28}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_127", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 24, "block_id": 54, "raw_label": "reference_content", "raw_order": 52, "bbox": [612, 950, 1089, 986], "text": "[96] H. Y. Jang, J. Y. Shin, Se H Oh, J-Ho Byun, J Ho Lee, ACS Biomater. Sci. Eng. 2020, 6, 5172.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [96] H. Y. Jang, J. Y. Shin, Se H Oh, J-Ho Byun, J Ho Lee, A"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [96] H. Y. Jang, J. Y. Shin, Se H Oh, J-Ho Byun, J Ho Lee, A"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 54, "page": 24, "raw_label": "reference_content", "text": "[96] H. Y. Jang, J. Y. Shin, Se H Oh, J-Ho Byun, J Ho Lee, ACS Biomater. Sci. Eng. 2020, 6, 5172.", "bbox": [612, 950, 1089, 986], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[96]", "number": 96, "kind": "reference", "normalized_text": "[96] H. Y. Jang, J. Y. Shin, Se H Oh, J-Ho Byun, J Ho Lee, ACS Biomater. Sci. Eng. 2020, 6, 5172."}, "layout_signature": {"width": 477, "width_bucket": 475, "height": 36, "left": 612, "top": 950, "right": 1089, "bottom": 986, "x_center": 850.5, "x_center_bucket": 850, "y_center": 968.0, "x_ratio": 0.7141, "y_ratio": 0.6185, "width_ratio": 0.4005, "height_ratio": 0.023, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 9}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_127", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 24, "block_id": 55, "raw_label": "reference_content", "raw_order": 53, "bbox": [613, 988, 1090, 1026], "text": "[97] Z. Fu, D. Li, J. Cui, H. Xu, C. Yuan, P. Wang, B. Zhao, K. Lin, Mater. Design 2023, 226, 111671.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [97] Z. Fu, D. Li, J. Cui, H. Xu, C. Yuan, P. Wang, B. Zhao,"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [97] Z. Fu, D. Li, J. Cui, H. Xu, C. Yuan, P. Wang, B. Zhao,"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 55, "page": 24, "raw_label": "reference_content", "text": "[97] Z. Fu, D. Li, J. Cui, H. Xu, C. Yuan, P. Wang, B. Zhao, K. Lin, Mater. Design 2023, 226, 111671.", "bbox": [613, 988, 1090, 1026], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[97]", "number": 97, "kind": "reference", "normalized_text": "[97] Z. Fu, D. Li, J. Cui, H. Xu, C. Yuan, P. Wang, B. Zhao, K. Lin, Mater. Design 2023, 226, 111671."}, "layout_signature": {"width": 477, "width_bucket": 475, "height": 38, "left": 613, "top": 988, "right": 1090, "bottom": 1026, "x_center": 851.5, "x_center_bucket": 850, "y_center": 1007.0, "x_ratio": 0.7149, "y_ratio": 0.6435, "width_ratio": 0.4005, "height_ratio": 0.0243, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 9}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_127", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 24, "block_id": 56, "raw_label": "reference_content", "raw_order": 54, "bbox": [613, 1028, 1090, 1085], "text": "[98] M. Yazdimamaghani, M. Razavi, D. Vashaee, K. Moharamzadeh, A. R. Boccaccini, L. Tayebi, Mater. Sci. Eng. C Mater. Biol. Appl. 2017, 71, 1253.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [98] M. Yazdimamaghani, M. Razavi, D. Vashaee, K. Moharamzad"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [98] M. Yazdimamaghani, M. Razavi, D. Vashaee, K. Moharamzad"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 56, "page": 24, "raw_label": "reference_content", "text": "[98] M. Yazdimamaghani, M. Razavi, D. Vashaee, K. Moharamzadeh, A. R. Boccaccini, L. Tayebi, Mater. Sci. Eng. C Mater. Biol. Appl. 2017, 71, 1253.", "bbox": [613, 1028, 1090, 1085], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[98]", "number": 98, "kind": "reference", "normalized_text": "[98] M. Yazdimamaghani, M. Razavi, D. Vashaee, K. Moharamzadeh, A. R. Boccaccini, L. Tayebi, Mater. Sci. Eng. C Mater. Biol. Appl. 2017, 71, 1253."}, "layout_signature": {"width": 477, "width_bucket": 475, "height": 57, "left": 613, "top": 1028, "right": 1090, "bottom": 1085, "x_center": 851.5, "x_center_bucket": 850, "y_center": 1056.5, "x_ratio": 0.7149, "y_ratio": 0.6751, "width_ratio": 0.4005, "height_ratio": 0.0364, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 29}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_127", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 24, "block_id": 57, "raw_label": "reference_content", "raw_order": 55, "bbox": [610, 1088, 1090, 1127], "text": "[99] N. Hu, Y. Wu, L. Xie, S. M. Yusuf, N. Gao, M. J. Starink, L. Tong, P. K. Chu, H. Wang, Acta Biomater. 2020, 106, 360.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [99] N. Hu, Y. Wu, L. Xie, S. M. Yusuf, N. Gao, M. J. Starin"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [99] N. Hu, Y. Wu, L. Xie, S. M. Yusuf, N. Gao, M. J. Starin"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 57, "page": 24, "raw_label": "reference_content", "text": "[99] N. Hu, Y. Wu, L. Xie, S. M. Yusuf, N. Gao, M. J. Starink, L. Tong, P. K. Chu, H. Wang, Acta Biomater. 2020, 106, 360.", "bbox": [610, 1088, 1090, 1127], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[99]", "number": 99, "kind": "reference", "normalized_text": "[99] N. Hu, Y. Wu, L. Xie, S. M. Yusuf, N. Gao, M. J. Starink, L. Tong, P. K. Chu, H. Wang, Acta Biomater. 2020, 106, 360."}, "layout_signature": {"width": 480, "width_bucket": 475, "height": 39, "left": 610, "top": 1088, "right": 1090, "bottom": 1127, "x_center": 850.0, "x_center_bucket": 850, "y_center": 1107.5, "x_ratio": 0.7137, "y_ratio": 0.7077, "width_ratio": 0.403, "height_ratio": 0.0249, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 9}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_127", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 24, "block_id": 58, "raw_label": "reference_content", "raw_order": 56, "bbox": [607, 1128, 1048, 1147], "text": "[100] S. Noreen, E. Wang, H. Feng, Z. Li, Materials 2022, 15, 6868.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [100] S. Noreen, E. Wang, H. Feng, Z. Li, Materials 2022, 15"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [100] S. Noreen, E. Wang, H. Feng, Z. Li, Materials 2022, 15"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 58, "page": 24, "raw_label": "reference_content", "text": "[100] S. Noreen, E. Wang, H. Feng, Z. Li, Materials 2022, 15, 6868.", "bbox": [607, 1128, 1048, 1147], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[100]", "number": 100, "kind": "reference", "normalized_text": "[100] S. Noreen, E. Wang, H. Feng, Z. Li, Materials 2022, 15, 6868."}, "layout_signature": {"width": 441, "width_bucket": 450, "height": 19, "left": 607, "top": 1128, "right": 1048, "bottom": 1147, "x_center": 827.5, "x_center_bucket": 825, "y_center": 1137.5, "x_ratio": 0.6948, "y_ratio": 0.7268, "width_ratio": 0.3703, "height_ratio": 0.0121, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 8}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_127", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 24, "block_id": 59, "raw_label": "reference_content", "raw_order": 57, "bbox": [605, 1149, 1054, 1167], "text": "[101] M. Zhai, Ye Zhu, M. Yang, C. Mao, Adv. Sci. 2020, 7, 2001334.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [101] M. Zhai, Ye Zhu, M. Yang, C. Mao, Adv. Sci. 2020, 7, 2"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [101] M. Zhai, Ye Zhu, M. Yang, C. Mao, Adv. Sci. 2020, 7, 2"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 59, "page": 24, "raw_label": "reference_content", "text": "[101] M. Zhai, Ye Zhu, M. Yang, C. Mao, Adv. Sci. 2020, 7, 2001334.", "bbox": [605, 1149, 1054, 1167], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[101]", "number": 101, "kind": "reference", "normalized_text": "[101] M. Zhai, Ye Zhu, M. Yang, C. Mao, Adv. Sci. 2020, 7, 2001334."}, "layout_signature": {"width": 449, "width_bucket": 450, "height": 18, "left": 605, "top": 1149, "right": 1054, "bottom": 1167, "x_center": 829.5, "x_center_bucket": 825, "y_center": 1158.0, "x_ratio": 0.6965, "y_ratio": 0.7399, "width_ratio": 0.377, "height_ratio": 0.0115, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 8}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_127", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 24, "block_id": 60, "raw_label": "reference_content", "raw_order": 58, "bbox": [605, 1170, 1090, 1205], "text": "[102] Z. Wu, P. Pu, Z. Su, X. Zhang, L. Nie, Y. Chang, Biochem. Biophys. Res. Commun. 2020, 531, 559.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [102] Z. Wu, P. Pu, Z. Su, X. Zhang, L. Nie, Y. Chang, Bioch"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [102] Z. Wu, P. Pu, Z. Su, X. Zhang, L. Nie, Y. Chang, Bioch"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 60, "page": 24, "raw_label": "reference_content", "text": "[102] Z. Wu, P. Pu, Z. Su, X. Zhang, L. Nie, Y. Chang, Biochem. Biophys. Res. Commun. 2020, 531, 559.", "bbox": [605, 1170, 1090, 1205], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[102]", "number": 102, "kind": "reference", "normalized_text": "[102] Z. Wu, P. Pu, Z. Su, X. Zhang, L. Nie, Y. Chang, Biochem. Biophys. Res. Commun. 2020, 531, 559."}, "layout_signature": {"width": 485, "width_bucket": 475, "height": 35, "left": 605, "top": 1170, "right": 1090, "bottom": 1205, "x_center": 847.5, "x_center_bucket": 850, "y_center": 1187.5, "x_ratio": 0.7116, "y_ratio": 0.7588, "width_ratio": 0.4072, "height_ratio": 0.0224, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 34}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_127", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 24, "block_id": 61, "raw_label": "reference_content", "raw_order": 59, "bbox": [605, 1208, 1090, 1245], "text": "[103] X. Qu, H. Yang, Z. Yu, Bo Jia, H. Qiao, Y. Zheng, K. Dai, Bioac. Mater. 2020, 5, 410.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [103] X. Qu, H. Yang, Z. Yu, Bo Jia, H. Qiao, Y. Zheng, K. D"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [103] X. Qu, H. Yang, Z. Yu, Bo Jia, H. Qiao, Y. Zheng, K. D"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 61, "page": 24, "raw_label": "reference_content", "text": "[103] X. Qu, H. Yang, Z. Yu, Bo Jia, H. Qiao, Y. Zheng, K. Dai, Bioac. Mater. 2020, 5, 410.", "bbox": [605, 1208, 1090, 1245], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[103]", "number": 103, "kind": "reference", "normalized_text": "[103] X. Qu, H. Yang, Z. Yu, Bo Jia, H. Qiao, Y. Zheng, K. Dai, Bioac. Mater. 2020, 5, 410."}, "layout_signature": {"width": 485, "width_bucket": 475, "height": 37, "left": 605, "top": 1208, "right": 1090, "bottom": 1245, "x_center": 847.5, "x_center_bucket": 850, "y_center": 1226.5, "x_ratio": 0.7116, "y_ratio": 0.7837, "width_ratio": 0.4072, "height_ratio": 0.0236, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 8}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_127", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 24, "block_id": 62, "raw_label": "reference_content", "raw_order": 60, "bbox": [605, 1247, 1090, 1285], "text": "[104] Y. Li, J. Yue, Y. Liu, J. Wu, M. Guan, Di Chen, H. Pan, X. Zhao, W. W. Lu, Acta Biomater. 2021, 119, 432.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [104] Y. Li, J. Yue, Y. Liu, J. Wu, M. Guan, Di Chen, H. Pan"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [104] Y. Li, J. Yue, Y. Liu, J. Wu, M. Guan, Di Chen, H. Pan"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 62, "page": 24, "raw_label": "reference_content", "text": "[104] Y. Li, J. Yue, Y. Liu, J. Wu, M. Guan, Di Chen, H. Pan, X. Zhao, W. W. Lu, Acta Biomater. 2021, 119, 432.", "bbox": [605, 1247, 1090, 1285], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[104]", "number": 104, "kind": "reference", "normalized_text": "[104] Y. Li, J. Yue, Y. Liu, J. Wu, M. Guan, Di Chen, H. Pan, X. Zhao, W. W. Lu, Acta Biomater. 2021, 119, 432."}, "layout_signature": {"width": 485, "width_bucket": 475, "height": 38, "left": 605, "top": 1247, "right": 1090, "bottom": 1285, "x_center": 847.5, "x_center_bucket": 850, "y_center": 1266.0, "x_ratio": 0.7116, "y_ratio": 0.8089, "width_ratio": 0.4072, "height_ratio": 0.0243, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 9}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_127", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 24, "block_id": 63, "raw_label": "reference_content", "raw_order": 61, "bbox": [605, 1287, 1090, 1345], "text": "[105] K. Glenske, P. Donkiewicz, A. Köwitsch, N. Milosevic-Oljaca, P. Rider, S. Rofall, J. Franke, O. Jung, R. Smeets, R. Schnettler, S. Wenisch, M. Barbeck, Int. J. Mol. Sci. 2018, 19, 826.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [105] K. Glenske, P. Donkiewicz, A. Köwitsch, N. Milosevic-O"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [105] K. Glenske, P. Donkiewicz, A. Köwitsch, N. Milosevic-O"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 63, "page": 24, "raw_label": "reference_content", "text": "[105] K. Glenske, P. Donkiewicz, A. Köwitsch, N. Milosevic-Oljaca, P. Rider, S. Rofall, J. Franke, O. Jung, R. Smeets, R. Schnettler, S. Wenisch, M. Barbeck, Int. J. Mol. Sci. 2018, 19, 826.", "bbox": [605, 1287, 1090, 1345], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[105]", "number": 105, "kind": "reference", "normalized_text": "[105] K. Glenske, P. Donkiewicz, A. Köwitsch, N. Milosevic-Oljaca, P. Rider, S. Rofall, J. Franke, O. Jung, R. Smeets, R. Schnettler, S. Wenisch, M. Barbeck, Int. J. Mol. Sci. 2018, 19, 826."}, "layout_signature": {"width": 485, "width_bucket": 475, "height": 58, "left": 605, "top": 1287, "right": 1090, "bottom": 1345, "x_center": 847.5, "x_center_bucket": 850, "y_center": 1316.0, "x_ratio": 0.7116, "y_ratio": 0.8409, "width_ratio": 0.4072, "height_ratio": 0.0371, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 48}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_127", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 24, "block_id": 64, "raw_label": "reference_content", "raw_order": 62, "bbox": [605, 1348, 1091, 1404], "text": "[106] K. Jähn, H. Saito, H. Taipaleenmäki, A. Gasser, N. Hort, F. Feyerabend, H. Schlüter, J. M. Rueger, W. Lehmann, R. Willumeit-Römer, E. Hesse, Acta Biomater. 2016, 36, 350.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [106] K. Jähn, H. Saito, H. Taipaleenmäki, A. Gasser, N. Hor"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [106] K. Jähn, H. Saito, H. Taipaleenmäki, A. Gasser, N. Hor"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 64, "page": 24, "raw_label": "reference_content", "text": "[106] K. Jähn, H. Saito, H. Taipaleenmäki, A. Gasser, N. Hort, F. Feyerabend, H. Schlüter, J. M. Rueger, W. Lehmann, R. Willumeit-Römer, E. Hesse, Acta Biomater. 2016, 36, 350.", "bbox": [605, 1348, 1091, 1404], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[106]", "number": 106, "kind": "reference", "normalized_text": "[106] K. Jähn, H. Saito, H. Taipaleenmäki, A. Gasser, N. Hort, F. Feyerabend, H. Schlüter, J. M. Rueger, W. Lehmann, R. Willumeit-Römer, E. Hesse, Acta Biomater. 2016, 36, 350."}, "layout_signature": {"width": 486, "width_bucket": 475, "height": 56, "left": 605, "top": 1348, "right": 1091, "bottom": 1404, "x_center": 848.0, "x_center_bucket": 850, "y_center": 1376.0, "x_ratio": 0.712, "y_ratio": 0.8792, "width_ratio": 0.4081, "height_ratio": 0.0358, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 48}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_127", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 24, "block_id": 65, "raw_label": "reference_content", "raw_order": 63, "bbox": [604, 1407, 1018, 1426], "text": "[107] J. J. Li, N. Kawazoe, G. Chen, Biomaterials 2015, 54, 226.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [107] J. J. Li, N. Kawazoe, G. Chen, Biomaterials 2015, 54, "], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [107] J. J. Li, N. Kawazoe, G. Chen, Biomaterials 2015, 54, "], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 65, "page": 24, "raw_label": "reference_content", "text": "[107] J. J. Li, N. Kawazoe, G. Chen, Biomaterials 2015, 54, 226.", "bbox": [604, 1407, 1018, 1426], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[107]", "number": 107, "kind": "reference", "normalized_text": "[107] J. J. Li, N. Kawazoe, G. Chen, Biomaterials 2015, 54, 226."}, "layout_signature": {"width": 414, "width_bucket": 425, "height": 19, "left": 604, "top": 1407, "right": 1018, "bottom": 1426, "x_center": 811.0, "x_center_bucket": 800, "y_center": 1416.5, "x_ratio": 0.6809, "y_ratio": 0.9051, "width_ratio": 0.3476, "height_ratio": 0.0121, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 8}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_127", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 24, "block_id": 66, "raw_label": "footer", "raw_order": null, "bbox": [94, 1488, 283, 1504], "text": "Small Methods 2024, 8, 2301283", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["footer label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["footer label"], "span_metadata": [{"size": 6.973800182342529, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 66, "page": 24, "raw_label": "footer", "text": "Small Methods 2024, 8, 2301283", "bbox": [94, 1488, 283, 1504], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "Small Methods 2024, 8, 2301283"}, "layout_signature": {"width": 189, "width_bucket": 200, "height": 16, "left": 94, "top": 1488, "right": 283, "bottom": 1504, "x_center": 188.5, "x_center_bucket": 200, "y_center": 1496.0, "x_ratio": 0.1583, "y_ratio": 0.9559, "width_ratio": 0.1587, "height_ratio": 0.0102, "line_count": 1}, "span_signature": {"font_size": 6.97, "font_size_median": 6.97, "font_size_bucket": 7.0, "font_family_norm": "ScalaSansPro-Italic", "bold": true, "italic": true, "span_count": 5}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_125", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 24, "block_id": 67, "raw_label": "footer", "raw_order": null, "bbox": [521, 1485, 663, 1506], "text": "2301283 (24 of 27)", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.9, "evidence": ["footer label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["footer label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaSansPro-Bold", "flags": 20, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 67, "page": 24, "raw_label": "footer", "text": "2301283 (24 of 27)", "bbox": [521, 1485, 663, 1506], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_dot", "raw_marker": "2301283", "number": 2301283, "kind": "reference", "normalized_text": "2301283 (24 of 27)"}, "layout_signature": {"width": 142, "width_bucket": 150, "height": 21, "left": 521, "top": 1485, "right": 663, "bottom": 1506, "x_center": 592.0, "x_center_bucket": 600, "y_center": 1495.5, "x_ratio": 0.4971, "y_ratio": 0.9556, "width_ratio": 0.1192, "height_ratio": 0.0134, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaSansPro-Bold", "bold": true, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_family_anchor", "reading_band_id": "band_126", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "hard", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 24, "block_id": 68, "raw_label": "footer", "raw_order": null, "bbox": [932, 1488, 1090, 1505], "text": "© 2024 Wiley-VCH GmbH", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["footer label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["footer label"], "span_metadata": [{"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 68, "page": 24, "raw_label": "footer", "text": "© 2024 Wiley-VCH GmbH", "bbox": [932, 1488, 1090, 1505], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "© 2024 Wiley-VCH GmbH"}, "layout_signature": {"width": 158, "width_bucket": 150, "height": 17, "left": 932, "top": 1488, "right": 1090, "bottom": 1505, "x_center": 1011.0, "x_center_bucket": 1000, "y_center": 1496.5, "x_ratio": 0.8489, "y_ratio": 0.9562, "width_ratio": 0.1327, "height_ratio": 0.0109, "line_count": 1}, "span_signature": {"font_size": 6.97, "font_size_median": 6.97, "font_size_bucket": 7.0, "font_family_norm": "ScalaSansPro-Regular", "bold": false, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_128", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 24, "block_id": 69, "raw_label": "aside_text", "raw_order": null, "bbox": [1155, 33, 1171, 1536], "text": "2369608, 2024, 8, Downloaded from https://onlinelibrary.wiley.com/doi/10.1002/smd.202301283 by Shandong University Library, Wiley Online Library on [18/02/2026]. See the Terms and Conditions (https://onlinelibrary.wiley.com/terms-and-conditions) on Wiley Online Library for rules of use; OA articles are governed by the applicable Creative Commons License.", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.95, "evidence": ["margin-band narrow/tall geometry; treated as noise"], "seed_role": "noise", "seed_confidence": 0.95, "seed_evidence": ["margin-band narrow/tall geometry; treated as noise"], "span_metadata": [{"size": 5.03000020980835, "font": "Times-Roman", "flags": 4, "color": 0, "dir": [0.0, 1.0], "wmode": 0}], "raw_observation": {"block_id": 69, "page": 24, "raw_label": "aside_text", "text": "2369608, 2024, 8, Downloaded from https://onlinelibrary.wiley.com/doi/10.1002/smd.202301283 by Shandong University Library, Wiley Online Library on [18/02/2026]. See the Terms and Conditions (https://onlinelibrary.wiley.com/terms-and-conditions) on Wiley Online Library for rules of use; OA articles are governed by the applicable Creative Commons License.", "bbox": [1155, 33, 1171, 1536], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "2369608, 2024, 8, Downloaded from https://onlinelibrary.wiley.com/doi/10.1002/smd.202301283 by Shandong University Library, Wiley Online Library on [18/02/2026]. See the Terms and Conditions (https://onlinelibrary.wiley.com/terms-and-conditions) on Wiley Online Library for rules of use; OA articles are governed by the applicable Creative Commons License."}, "layout_signature": {"width": 16, "width_bucket": 25, "height": 1503, "left": 1155, "top": 33, "right": 1171, "bottom": 1536, "x_center": 1163.0, "x_center_bucket": 1175, "y_center": 784.5, "x_ratio": 0.9765, "y_ratio": 0.5013, "width_ratio": 0.0134, "height_ratio": 0.9604, "line_count": 1}, "span_signature": {"font_size": 5.03, "font_size_median": 5.03, "font_size_bucket": 5.0, "font_family_norm": "Times-Roman", "bold": false, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_128", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 25, "block_id": 0, "raw_label": "header", "raw_order": null, "bbox": [98, 46, 344, 116], "text": "ADVANCED\nSCIENCE NEWS\nwww.advancedsciencenews.com", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["header label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["header label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaSansPro-Bold", "flags": 20, "color": 255, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 0, "page": 25, "raw_label": "header", "text": "ADVANCED\nSCIENCE NEWS\nwww.advancedsciencenews.com", "bbox": [98, 46, 344, 116], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "ADVANCED\nSCIENCE NEWS\nwww.advancedsciencenews.com"}, "layout_signature": {"width": 246, "width_bucket": 250, "height": 70, "left": 98, "top": 46, "right": 344, "bottom": 116, "x_center": 221.0, "x_center_bucket": 225, "y_center": 81.0, "x_ratio": 0.1856, "y_ratio": 0.0518, "width_ratio": 0.2065, "height_ratio": 0.0447, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaSansPro-Bold", "bold": true, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 25, "block_id": 1, "raw_label": "header_image", "raw_order": null, "bbox": [1003, 37, 1095, 96], "text": "", "page_width": 1191, "page_height": 1565, "role": "unknown_structural", "role_confidence": 0.2, "evidence": ["unrecognized label 'header_image'"], "seed_role": "unknown_structural", "seed_confidence": 0.2, "seed_evidence": ["unrecognized label 'header_image'"], "span_metadata": null, "raw_observation": {"block_id": 1, "page": 25, "raw_label": "header_image", "text": "", "bbox": [1003, 37, 1095, 96], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "empty", "raw_marker": null, "number": null, "kind": null, "normalized_text": ""}, "layout_signature": {"width": 92, "width_bucket": 100, "height": 59, "left": 1003, "top": 37, "right": 1095, "bottom": 96, "x_center": 1049.0, "x_center_bucket": 1050, "y_center": 66.5, "x_ratio": 0.8808, "y_ratio": 0.0425, "width_ratio": 0.0772, "height_ratio": 0.0377, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": true, "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_142", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["non-structural role accepted"]}
+{"paper_id": "2HEUD5P9", "page": 25, "block_id": 2, "raw_label": "header", "raw_order": null, "bbox": [903, 98, 1095, 115], "text": "www.small-methods.com", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["header label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["header label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaSansPro-Bold", "flags": 20, "color": 255, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 2, "page": 25, "raw_label": "header", "text": "www.small-methods.com", "bbox": [903, 98, 1095, 115], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "www.small-methods.com"}, "layout_signature": {"width": 192, "width_bucket": 200, "height": 17, "left": 903, "top": 98, "right": 1095, "bottom": 115, "x_center": 999.0, "x_center_bucket": 1000, "y_center": 106.5, "x_ratio": 0.8388, "y_ratio": 0.0681, "width_ratio": 0.1612, "height_ratio": 0.0109, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaSansPro-Bold", "bold": true, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_142", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 25, "block_id": 3, "raw_label": "reference_content", "raw_order": 1, "bbox": [98, 151, 586, 189], "text": "[108] J. Li, J. J. Li, J. Zhang, X. Wang, N. Kawazoe, G. Chen, Nanoscale 2016, 8, 7992.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [108] J. Li, J. J. Li, J. Zhang, X. Wang, N. Kawazoe, G. Che"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [108] J. Li, J. J. Li, J. Zhang, X. Wang, N. Kawazoe, G. Che"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 3, "page": 25, "raw_label": "reference_content", "text": "[108] J. Li, J. J. Li, J. Zhang, X. Wang, N. Kawazoe, G. Chen, Nanoscale 2016, 8, 7992.", "bbox": [98, 151, 586, 189], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[108]", "number": 108, "kind": "reference", "normalized_text": "[108] J. Li, J. J. Li, J. Zhang, X. Wang, N. Kawazoe, G. Chen, Nanoscale 2016, 8, 7992."}, "layout_signature": {"width": 488, "width_bucket": 500, "height": 38, "left": 98, "top": 151, "right": 586, "bottom": 189, "x_center": 342.0, "x_center_bucket": 350, "y_center": 170.0, "x_ratio": 0.2872, "y_ratio": 0.1086, "width_ratio": 0.4097, "height_ratio": 0.0243, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 33}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_139", "display_cluster_candidate_id": "disp_27_0", "layout_region": "display_zone", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 25, "block_id": 4, "raw_label": "reference_content", "raw_order": 2, "bbox": [99, 191, 586, 247], "text": "[109] R. Zhang, P. Lee, V. C. H. Lui, Y. Chen, X. Liu, C. N. Lok, M. To, K. W. K. Yeung, K. K. Y. Wong, Nanomed. Nanotechnol Biol. Med. 2015, 11, 1949.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [109] R. Zhang, P. Lee, V. C. H. Lui, Y. Chen, X. Liu, C. N."], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [109] R. Zhang, P. Lee, V. C. H. Lui, Y. Chen, X. Liu, C. N."], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 4, "page": 25, "raw_label": "reference_content", "text": "[109] R. Zhang, P. Lee, V. C. H. Lui, Y. Chen, X. Liu, C. N. Lok, M. To, K. W. K. Yeung, K. K. Y. Wong, Nanomed. Nanotechnol Biol. Med. 2015, 11, 1949.", "bbox": [99, 191, 586, 247], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[109]", "number": 109, "kind": "reference", "normalized_text": "[109] R. Zhang, P. Lee, V. C. H. Lui, Y. Chen, X. Liu, C. N. Lok, M. To, K. W. K. Yeung, K. K. Y. Wong, Nanomed. Nanotechnol Biol. Med. 2015, 11, 1949."}, "layout_signature": {"width": 487, "width_bucket": 475, "height": 56, "left": 99, "top": 191, "right": 586, "bottom": 247, "x_center": 342.5, "x_center_bucket": 350, "y_center": 219.0, "x_ratio": 0.2876, "y_ratio": 0.1399, "width_ratio": 0.4089, "height_ratio": 0.0358, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 41}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_140", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 25, "block_id": 5, "raw_label": "reference_content", "raw_order": 3, "bbox": [100, 250, 585, 289], "text": "[110] J. Chen, X. Zhang, C. Huang, He Cai, S. Hu, Q. Wan, X. Pei, J. Wang, J. Biomed. Mater. Res., Part A 2017, 105, 834.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [110] J. Chen, X. Zhang, C. Huang, He Cai, S. Hu, Q. Wan, X."], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [110] J. Chen, X. Zhang, C. Huang, He Cai, S. Hu, Q. Wan, X."], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 5, "page": 25, "raw_label": "reference_content", "text": "[110] J. Chen, X. Zhang, C. Huang, He Cai, S. Hu, Q. Wan, X. Pei, J. Wang, J. Biomed. Mater. Res., Part A 2017, 105, 834.", "bbox": [100, 250, 585, 289], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[110]", "number": 110, "kind": "reference", "normalized_text": "[110] J. Chen, X. Zhang, C. Huang, He Cai, S. Hu, Q. Wan, X. Pei, J. Wang, J. Biomed. Mater. Res., Part A 2017, 105, 834."}, "layout_signature": {"width": 485, "width_bucket": 475, "height": 39, "left": 100, "top": 250, "right": 585, "bottom": 289, "x_center": 342.5, "x_center_bucket": 350, "y_center": 269.5, "x_ratio": 0.2876, "y_ratio": 0.1722, "width_ratio": 0.4072, "height_ratio": 0.0249, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 8}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_139", "display_cluster_candidate_id": "disp_27_0", "layout_region": "display_zone", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 25, "block_id": 6, "raw_label": "reference_content", "raw_order": 4, "bbox": [99, 290, 586, 330], "text": "[111] Z. Zhu, S. Jiang, Y. Liu, X. Gao, S. Hu, X. Zhang, C. Huang, Q. Wan, J. Wang, X. Pei, Nano Res. 2020, 13, 511.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [111] Z. Zhu, S. Jiang, Y. Liu, X. Gao, S. Hu, X. Zhang, C. "], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [111] Z. Zhu, S. Jiang, Y. Liu, X. Gao, S. Hu, X. Zhang, C. "], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 6, "page": 25, "raw_label": "reference_content", "text": "[111] Z. Zhu, S. Jiang, Y. Liu, X. Gao, S. Hu, X. Zhang, C. Huang, Q. Wan, J. Wang, X. Pei, Nano Res. 2020, 13, 511.", "bbox": [99, 290, 586, 330], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[111]", "number": 111, "kind": "reference", "normalized_text": "[111] Z. Zhu, S. Jiang, Y. Liu, X. Gao, S. Hu, X. Zhang, C. Huang, Q. Wan, J. Wang, X. Pei, Nano Res. 2020, 13, 511."}, "layout_signature": {"width": 487, "width_bucket": 475, "height": 40, "left": 99, "top": 290, "right": 586, "bottom": 330, "x_center": 342.5, "x_center_bucket": 350, "y_center": 310.0, "x_ratio": 0.2876, "y_ratio": 0.1981, "width_ratio": 0.4089, "height_ratio": 0.0256, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 9}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_140", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 25, "block_id": 7, "raw_label": "reference_content", "raw_order": 5, "bbox": [99, 331, 585, 368], "text": "[112] Y. Kang, C. Xu, L. Meng, X. Dong, M. Qi, D. Jiang, Bioact. Mater. 2022, 18, 26.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [112] Y. Kang, C. Xu, L. Meng, X. Dong, M. Qi, D. Jiang, Bio"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [112] Y. Kang, C. Xu, L. Meng, X. Dong, M. Qi, D. Jiang, Bio"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 7, "page": 25, "raw_label": "reference_content", "text": "[112] Y. Kang, C. Xu, L. Meng, X. Dong, M. Qi, D. Jiang, Bioact. Mater. 2022, 18, 26.", "bbox": [99, 331, 585, 368], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[112]", "number": 112, "kind": "reference", "normalized_text": "[112] Y. Kang, C. Xu, L. Meng, X. Dong, M. Qi, D. Jiang, Bioact. Mater. 2022, 18, 26."}, "layout_signature": {"width": 486, "width_bucket": 475, "height": 37, "left": 99, "top": 331, "right": 585, "bottom": 368, "x_center": 342.0, "x_center_bucket": 350, "y_center": 349.5, "x_ratio": 0.2872, "y_ratio": 0.2233, "width_ratio": 0.4081, "height_ratio": 0.0236, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 33}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_139", "display_cluster_candidate_id": "disp_27_0", "layout_region": "display_zone", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 25, "block_id": 8, "raw_label": "reference_content", "raw_order": 6, "bbox": [99, 370, 585, 426], "text": "[113] Y. Xue, Z. Zhu, X. Zhang, J. Chen, X. Yang, X. Gao, S. Zhang, F. Luo, J. Wang, W. Zhao, C. Huang, X. Pei, Q. Wan, Adv. Healthcare Mater. 2021, 10, 2001369.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [113] Y. Xue, Z. Zhu, X. Zhang, J. Chen, X. Yang, X. Gao, S."], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [113] Y. Xue, Z. Zhu, X. Zhang, J. Chen, X. Yang, X. Gao, S."], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 8, "page": 25, "raw_label": "reference_content", "text": "[113] Y. Xue, Z. Zhu, X. Zhang, J. Chen, X. Yang, X. Gao, S. Zhang, F. Luo, J. Wang, W. Zhao, C. Huang, X. Pei, Q. Wan, Adv. Healthcare Mater. 2021, 10, 2001369.", "bbox": [99, 370, 585, 426], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[113]", "number": 113, "kind": "reference", "normalized_text": "[113] Y. Xue, Z. Zhu, X. Zhang, J. Chen, X. Yang, X. Gao, S. Zhang, F. Luo, J. Wang, W. Zhao, C. Huang, X. Pei, Q. Wan, Adv. Healthcare Mater. 2021, 10, 2001369."}, "layout_signature": {"width": 486, "width_bucket": 475, "height": 56, "left": 99, "top": 370, "right": 585, "bottom": 426, "x_center": 342.0, "x_center_bucket": 350, "y_center": 398.0, "x_ratio": 0.2872, "y_ratio": 0.2543, "width_ratio": 0.4081, "height_ratio": 0.0358, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 9}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_140", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 25, "block_id": 9, "raw_label": "reference_content", "raw_order": 7, "bbox": [99, 429, 585, 468], "text": "[114] V. K. Ameena Shirin, R. Sankar, A. P. Johnson, H. V. Gangadharappa, K. Pramod, J. Control. Release 2021, 330, 398.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [114] V. K. Ameena Shirin, R. Sankar, A. P. Johnson, H. V. G"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [114] V. K. Ameena Shirin, R. Sankar, A. P. Johnson, H. V. G"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 9, "page": 25, "raw_label": "reference_content", "text": "[114] V. K. Ameena Shirin, R. Sankar, A. P. Johnson, H. V. Gangadharappa, K. Pramod, J. Control. Release 2021, 330, 398.", "bbox": [99, 429, 585, 468], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[114]", "number": 114, "kind": "reference", "normalized_text": "[114] V. K. Ameena Shirin, R. Sankar, A. P. Johnson, H. V. Gangadharappa, K. Pramod, J. Control. Release 2021, 330, 398."}, "layout_signature": {"width": 486, "width_bucket": 475, "height": 39, "left": 99, "top": 429, "right": 585, "bottom": 468, "x_center": 342.0, "x_center_bucket": 350, "y_center": 448.5, "x_ratio": 0.2872, "y_ratio": 0.2866, "width_ratio": 0.4081, "height_ratio": 0.0249, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 9}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_138", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 25, "block_id": 10, "raw_label": "reference_content", "raw_order": 8, "bbox": [99, 510, 585, 547], "text": "[116] S. Cheng, D. Zhang, M. Li, X. Liu, Yu Zhang, S. Qian, F. Peng, Bioact. Mater. 2021, 6, 91.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [116] S. Cheng, D. Zhang, M. Li, X. Liu, Yu Zhang, S. Qian, "], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [116] S. Cheng, D. Zhang, M. Li, X. Liu, Yu Zhang, S. Qian, "], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 10, "page": 25, "raw_label": "reference_content", "text": "[116] S. Cheng, D. Zhang, M. Li, X. Liu, Yu Zhang, S. Qian, F. Peng, Bioact. Mater. 2021, 6, 91.", "bbox": [99, 510, 585, 547], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[116]", "number": 116, "kind": "reference", "normalized_text": "[116] S. Cheng, D. Zhang, M. Li, X. Liu, Yu Zhang, S. Qian, F. Peng, Bioact. Mater. 2021, 6, 91."}, "layout_signature": {"width": 486, "width_bucket": 475, "height": 37, "left": 99, "top": 510, "right": 585, "bottom": 547, "x_center": 342.0, "x_center_bucket": 350, "y_center": 528.5, "x_ratio": 0.2872, "y_ratio": 0.3377, "width_ratio": 0.4081, "height_ratio": 0.0236, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 9}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_141", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "hard", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 25, "block_id": 11, "raw_label": "reference_content", "raw_order": 9, "bbox": [100, 470, 585, 508], "text": "[115] L. Yang, X. He, G. Jing, H. Wang, J. Niu, Y. Qian, S. Wang, ACS Appl. Mater. Interfaces 2021, 13, 48386.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [115] L. Yang, X. He, G. Jing, H. Wang, J. Niu, Y. Qian, S. "], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [115] L. Yang, X. He, G. Jing, H. Wang, J. Niu, Y. Qian, S. "], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 11, "page": 25, "raw_label": "reference_content", "text": "[115] L. Yang, X. He, G. Jing, H. Wang, J. Niu, Y. Qian, S. Wang, ACS Appl. Mater. Interfaces 2021, 13, 48386.", "bbox": [100, 470, 585, 508], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[115]", "number": 115, "kind": "reference", "normalized_text": "[115] L. Yang, X. He, G. Jing, H. Wang, J. Niu, Y. Qian, S. Wang, ACS Appl. Mater. Interfaces 2021, 13, 48386."}, "layout_signature": {"width": 485, "width_bucket": 475, "height": 38, "left": 100, "top": 470, "right": 585, "bottom": 508, "x_center": 342.5, "x_center_bucket": 350, "y_center": 489.0, "x_ratio": 0.2876, "y_ratio": 0.3125, "width_ratio": 0.4072, "height_ratio": 0.0243, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 9}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_142", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 25, "block_id": 12, "raw_label": "reference_content", "raw_order": 10, "bbox": [99, 550, 585, 588], "text": "[117] N. Eskandari, S. S. Shafiei, M. M. Dehghan, S. Farzad-Mohajeri, J. Biomed. Mater. Res. B Appl. Biomater. 2022, 110, 1001.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [117] N. Eskandari, S. S. Shafiei, M. M. Dehghan, S. Farzad-"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [117] N. Eskandari, S. S. Shafiei, M. M. Dehghan, S. Farzad-"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 12, "page": 25, "raw_label": "reference_content", "text": "[117] N. Eskandari, S. S. Shafiei, M. M. Dehghan, S. Farzad-Mohajeri, J. Biomed. Mater. Res. B Appl. Biomater. 2022, 110, 1001.", "bbox": [99, 550, 585, 588], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[117]", "number": 117, "kind": "reference", "normalized_text": "[117] N. Eskandari, S. S. Shafiei, M. M. Dehghan, S. Farzad-Mohajeri, J. Biomed. Mater. Res. B Appl. Biomater. 2022, 110, 1001."}, "layout_signature": {"width": 486, "width_bucket": 475, "height": 38, "left": 99, "top": 550, "right": 585, "bottom": 588, "x_center": 342.0, "x_center_bucket": 350, "y_center": 569.0, "x_ratio": 0.2872, "y_ratio": 0.3636, "width_ratio": 0.4081, "height_ratio": 0.0243, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 28}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_142", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 25, "block_id": 13, "raw_label": "reference_content", "raw_order": 11, "bbox": [100, 590, 586, 628], "text": "[118] Yi-X Chen, R. Zhu, Q.-F. Ke, Y.-S. Gao, C.-Q. Zhang, Ya-P Guo, Nanoscale 2017, 9, 6765.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [118] Yi-X Chen, R. Zhu, Q.-F. Ke, Y.-S. Gao, C.-Q. Zhang, Y"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [118] Yi-X Chen, R. Zhu, Q.-F. Ke, Y.-S. Gao, C.-Q. Zhang, Y"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 13, "page": 25, "raw_label": "reference_content", "text": "[118] Yi-X Chen, R. Zhu, Q.-F. Ke, Y.-S. Gao, C.-Q. Zhang, Ya-P Guo, Nanoscale 2017, 9, 6765.", "bbox": [100, 590, 586, 628], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[118]", "number": 118, "kind": "reference", "normalized_text": "[118] Yi-X Chen, R. Zhu, Q.-F. Ke, Y.-S. Gao, C.-Q. Zhang, Ya-P Guo, Nanoscale 2017, 9, 6765."}, "layout_signature": {"width": 486, "width_bucket": 475, "height": 38, "left": 100, "top": 590, "right": 586, "bottom": 628, "x_center": 343.0, "x_center_bucket": 350, "y_center": 609.0, "x_ratio": 0.288, "y_ratio": 0.3891, "width_ratio": 0.4081, "height_ratio": 0.0243, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 30}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_136", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 25, "block_id": 14, "raw_label": "reference_content", "raw_order": 12, "bbox": [100, 630, 585, 668], "text": "[119] K. Li, H. Tian, Ai Guo, L. Jin, W. Chen, B. Tao, J. Biomed. Mater. Res., Part A 2022, 110, 273.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [119] K. Li, H. Tian, Ai Guo, L. Jin, W. Chen, B. Tao, J. Bi"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [119] K. Li, H. Tian, Ai Guo, L. Jin, W. Chen, B. Tao, J. Bi"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 14, "page": 25, "raw_label": "reference_content", "text": "[119] K. Li, H. Tian, Ai Guo, L. Jin, W. Chen, B. Tao, J. Biomed. Mater. Res., Part A 2022, 110, 273.", "bbox": [100, 630, 585, 668], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[119]", "number": 119, "kind": "reference", "normalized_text": "[119] K. Li, H. Tian, Ai Guo, L. Jin, W. Chen, B. Tao, J. Biomed. Mater. Res., Part A 2022, 110, 273."}, "layout_signature": {"width": 485, "width_bucket": 475, "height": 38, "left": 100, "top": 630, "right": 585, "bottom": 668, "x_center": 342.5, "x_center_bucket": 350, "y_center": 649.0, "x_ratio": 0.2876, "y_ratio": 0.4147, "width_ratio": 0.4072, "height_ratio": 0.0243, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 9}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_136", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 25, "block_id": 15, "raw_label": "reference_content", "raw_order": 13, "bbox": [99, 670, 584, 707], "text": "[120] Yu-W Ge, Z.-H. Fan, Q.-F. Ke, Ya-P Guo, C.-Q. Zhang, W.-T. Jia, Mater. Today Bio. 2022, 16, 100362.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [120] Yu-W Ge, Z.-H. Fan, Q.-F. Ke, Ya-P Guo, C.-Q. Zhang, W"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [120] Yu-W Ge, Z.-H. Fan, Q.-F. Ke, Ya-P Guo, C.-Q. Zhang, W"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 15, "page": 25, "raw_label": "reference_content", "text": "[120] Yu-W Ge, Z.-H. Fan, Q.-F. Ke, Ya-P Guo, C.-Q. Zhang, W.-T. Jia, Mater. Today Bio. 2022, 16, 100362.", "bbox": [99, 670, 584, 707], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[120]", "number": 120, "kind": "reference", "normalized_text": "[120] Yu-W Ge, Z.-H. Fan, Q.-F. Ke, Ya-P Guo, C.-Q. Zhang, W.-T. Jia, Mater. Today Bio. 2022, 16, 100362."}, "layout_signature": {"width": 485, "width_bucket": 475, "height": 37, "left": 99, "top": 670, "right": 584, "bottom": 707, "x_center": 341.5, "x_center_bucket": 350, "y_center": 688.5, "x_ratio": 0.2867, "y_ratio": 0.4399, "width_ratio": 0.4072, "height_ratio": 0.0236, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 9}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_136", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 25, "block_id": 16, "raw_label": "reference_content", "raw_order": 14, "bbox": [101, 709, 586, 746], "text": "[121] G. Wang, Z. Lv, T. Wang, T. Hu, Y. Bian, Yu Yang, R. Liang, C. Tan, X. Weng, Adv. Sci. 2022, 10, e2204234.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [121] G. Wang, Z. Lv, T. Wang, T. Hu, Y. Bian, Yu Yang, R. L"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [121] G. Wang, Z. Lv, T. Wang, T. Hu, Y. Bian, Yu Yang, R. L"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 16, "page": 25, "raw_label": "reference_content", "text": "[121] G. Wang, Z. Lv, T. Wang, T. Hu, Y. Bian, Yu Yang, R. Liang, C. Tan, X. Weng, Adv. Sci. 2022, 10, e2204234.", "bbox": [101, 709, 586, 746], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[121]", "number": 121, "kind": "reference", "normalized_text": "[121] G. Wang, Z. Lv, T. Wang, T. Hu, Y. Bian, Yu Yang, R. Liang, C. Tan, X. Weng, Adv. Sci. 2022, 10, e2204234."}, "layout_signature": {"width": 485, "width_bucket": 475, "height": 37, "left": 101, "top": 709, "right": 586, "bottom": 746, "x_center": 343.5, "x_center_bucket": 350, "y_center": 727.5, "x_ratio": 0.2884, "y_ratio": 0.4649, "width_ratio": 0.4072, "height_ratio": 0.0236, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 9}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_136", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 25, "block_id": 17, "raw_label": "reference_content", "raw_order": 15, "bbox": [100, 749, 585, 787], "text": "[122] S. E. Enderami, S. S. Shafiei, M. Shamsara, S. E. Enderami, A. Rostamian Tabari, Front. Bioeng. Biotechnol. 2022, 10, 805969.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [122] S. E. Enderami, S. S. Shafiei, M. Shamsara, S. E. Ende"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [122] S. E. Enderami, S. S. Shafiei, M. Shamsara, S. E. Ende"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 17, "page": 25, "raw_label": "reference_content", "text": "[122] S. E. Enderami, S. S. Shafiei, M. Shamsara, S. E. Enderami, A. Rostamian Tabari, Front. Bioeng. Biotechnol. 2022, 10, 805969.", "bbox": [100, 749, 585, 787], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[122]", "number": 122, "kind": "reference", "normalized_text": "[122] S. E. Enderami, S. S. Shafiei, M. Shamsara, S. E. Enderami, A. Rostamian Tabari, Front. Bioeng. Biotechnol. 2022, 10, 805969."}, "layout_signature": {"width": 485, "width_bucket": 475, "height": 38, "left": 100, "top": 749, "right": 585, "bottom": 787, "x_center": 342.5, "x_center_bucket": 350, "y_center": 768.0, "x_ratio": 0.2876, "y_ratio": 0.4907, "width_ratio": 0.4072, "height_ratio": 0.0243, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 31}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_136", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 25, "block_id": 18, "raw_label": "reference_content", "raw_order": 16, "bbox": [100, 789, 585, 827], "text": "[123] D. Zhang, S. Cheng, Ji Tan, J. Xie, Yu Zhang, S. Chen, H. Du, S. Qian, Y. Qiao, F. Peng, X. Liu, Bioact. Mater. 2022, 17, 394.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [123] D. Zhang, S. Cheng, Ji Tan, J. Xie, Yu Zhang, S. Chen,"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [123] D. Zhang, S. Cheng, Ji Tan, J. Xie, Yu Zhang, S. Chen,"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 18, "page": 25, "raw_label": "reference_content", "text": "[123] D. Zhang, S. Cheng, Ji Tan, J. Xie, Yu Zhang, S. Chen, H. Du, S. Qian, Y. Qiao, F. Peng, X. Liu, Bioact. Mater. 2022, 17, 394.", "bbox": [100, 789, 585, 827], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[123]", "number": 123, "kind": "reference", "normalized_text": "[123] D. Zhang, S. Cheng, Ji Tan, J. Xie, Yu Zhang, S. Chen, H. Du, S. Qian, Y. Qiao, F. Peng, X. Liu, Bioact. Mater. 2022, 17, 394."}, "layout_signature": {"width": 485, "width_bucket": 475, "height": 38, "left": 100, "top": 789, "right": 585, "bottom": 827, "x_center": 342.5, "x_center_bucket": 350, "y_center": 808.0, "x_ratio": 0.2876, "y_ratio": 0.5163, "width_ratio": 0.4072, "height_ratio": 0.0243, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 9}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_136", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 25, "block_id": 19, "raw_label": "reference_content", "raw_order": 17, "bbox": [99, 829, 585, 867], "text": "[124] A. Shavandi, A El-D. A. Bekhit, Z. Sun, A. Ali, M. Gould, Mater. Sci. Eng. C Mater. Biol. Appl. 2015, 55, 373.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [124] A. Shavandi, A El-D. A. Bekhit, Z. Sun, A. Ali, M. Gou"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [124] A. Shavandi, A El-D. A. Bekhit, Z. Sun, A. Ali, M. Gou"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 19, "page": 25, "raw_label": "reference_content", "text": "[124] A. Shavandi, A El-D. A. Bekhit, Z. Sun, A. Ali, M. Gould, Mater. Sci. Eng. C Mater. Biol. Appl. 2015, 55, 373.", "bbox": [99, 829, 585, 867], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[124]", "number": 124, "kind": "reference", "normalized_text": "[124] A. Shavandi, A El-D. A. Bekhit, Z. Sun, A. Ali, M. Gould, Mater. Sci. Eng. C Mater. Biol. Appl. 2015, 55, 373."}, "layout_signature": {"width": 486, "width_bucket": 475, "height": 38, "left": 99, "top": 829, "right": 585, "bottom": 867, "x_center": 342.0, "x_center_bucket": 350, "y_center": 848.0, "x_ratio": 0.2872, "y_ratio": 0.5419, "width_ratio": 0.4081, "height_ratio": 0.0243, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 9}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_136", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 25, "block_id": 20, "raw_label": "reference_content", "raw_order": 18, "bbox": [99, 869, 584, 907], "text": "[125] X. He, K. Tang, X. Li, F. Wang, J. Liu, F. Zou, M. Yang, M. Li, Int. J. Biol. Macromol. 2019, 137, 45.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [125] X. He, K. Tang, X. Li, F. Wang, J. Liu, F. Zou, M. Yan"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [125] X. He, K. Tang, X. Li, F. Wang, J. Liu, F. Zou, M. Yan"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 20, "page": 25, "raw_label": "reference_content", "text": "[125] X. He, K. Tang, X. Li, F. Wang, J. Liu, F. Zou, M. Yang, M. Li, Int. J. Biol. Macromol. 2019, 137, 45.", "bbox": [99, 869, 584, 907], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[125]", "number": 125, "kind": "reference", "normalized_text": "[125] X. He, K. Tang, X. Li, F. Wang, J. Liu, F. Zou, M. Yang, M. Li, Int. J. Biol. Macromol. 2019, 137, 45."}, "layout_signature": {"width": 485, "width_bucket": 475, "height": 38, "left": 99, "top": 869, "right": 584, "bottom": 907, "x_center": 341.5, "x_center_bucket": 350, "y_center": 888.0, "x_ratio": 0.2867, "y_ratio": 0.5674, "width_ratio": 0.4072, "height_ratio": 0.0243, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 19}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_136", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 25, "block_id": 21, "raw_label": "reference_content", "raw_order": 19, "bbox": [100, 909, 585, 947], "text": "[126] H. Zhang, X. Mao, Z. Du, W. Jiang, X. Han, D. Zhao, D. Han, Q. Li, Sci. Technol. Adv. Mater. 2016, 17, 136.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [126] H. Zhang, X. Mao, Z. Du, W. Jiang, X. Han, D. Zhao, D."], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [126] H. Zhang, X. Mao, Z. Du, W. Jiang, X. Han, D. Zhao, D."], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 21, "page": 25, "raw_label": "reference_content", "text": "[126] H. Zhang, X. Mao, Z. Du, W. Jiang, X. Han, D. Zhao, D. Han, Q. Li, Sci. Technol. Adv. Mater. 2016, 17, 136.", "bbox": [100, 909, 585, 947], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[126]", "number": 126, "kind": "reference", "normalized_text": "[126] H. Zhang, X. Mao, Z. Du, W. Jiang, X. Han, D. Zhao, D. Han, Q. Li, Sci. Technol. Adv. Mater. 2016, 17, 136."}, "layout_signature": {"width": 485, "width_bucket": 475, "height": 38, "left": 100, "top": 909, "right": 585, "bottom": 947, "x_center": 342.5, "x_center_bucket": 350, "y_center": 928.0, "x_ratio": 0.2876, "y_ratio": 0.593, "width_ratio": 0.4072, "height_ratio": 0.0243, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 8}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_133", "display_cluster_candidate_id": "disp_26_0", "layout_region": "display_zone", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 25, "block_id": 22, "raw_label": "reference_content", "raw_order": 20, "bbox": [99, 949, 585, 1005], "text": "[127] C. Esposito Corcione, F. Gervaso, F. Scalera, S. K. Padmanabhan, M. Madaghiele, F. Montagna, A. Sannino, A. Licciulli, A. Maffezzoli, Ceram. Int. 2019, 45, 2803.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [127] C. Esposito Corcione, F. Gervaso, F. Scalera, S. K. Pa"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [127] C. Esposito Corcione, F. Gervaso, F. Scalera, S. K. Pa"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 22, "page": 25, "raw_label": "reference_content", "text": "[127] C. Esposito Corcione, F. Gervaso, F. Scalera, S. K. Padmanabhan, M. Madaghiele, F. Montagna, A. Sannino, A. Licciulli, A. Maffezzoli, Ceram. Int. 2019, 45, 2803.", "bbox": [99, 949, 585, 1005], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[127]", "number": 127, "kind": "reference", "normalized_text": "[127] C. Esposito Corcione, F. Gervaso, F. Scalera, S. K. Padmanabhan, M. Madaghiele, F. Montagna, A. Sannino, A. Licciulli, A. Maffezzoli, Ceram. Int. 2019, 45, 2803."}, "layout_signature": {"width": 486, "width_bucket": 475, "height": 56, "left": 99, "top": 949, "right": 585, "bottom": 1005, "x_center": 342.0, "x_center_bucket": 350, "y_center": 977.0, "x_ratio": 0.2872, "y_ratio": 0.6243, "width_ratio": 0.4081, "height_ratio": 0.0358, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 27}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_134", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 25, "block_id": 23, "raw_label": "reference_content", "raw_order": 21, "bbox": [99, 1008, 585, 1047], "text": "[128] L. Kihlström Burenstam Linder, U. Birgersson, K. Lundgren, C. Illies, T. Engstrand, World Neurosurg. 2019, 122, e399.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [128] L. Kihlström Burenstam Linder, U. Birgersson, K. Lundg"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [128] L. Kihlström Burenstam Linder, U. Birgersson, K. Lundg"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 23, "page": 25, "raw_label": "reference_content", "text": "[128] L. Kihlström Burenstam Linder, U. Birgersson, K. Lundgren, C. Illies, T. Engstrand, World Neurosurg. 2019, 122, e399.", "bbox": [99, 1008, 585, 1047], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[128]", "number": 128, "kind": "reference", "normalized_text": "[128] L. Kihlström Burenstam Linder, U. Birgersson, K. Lundgren, C. Illies, T. Engstrand, World Neurosurg. 2019, 122, e399."}, "layout_signature": {"width": 486, "width_bucket": 475, "height": 39, "left": 99, "top": 1008, "right": 585, "bottom": 1047, "x_center": 342.0, "x_center_bucket": 350, "y_center": 1027.5, "x_ratio": 0.2872, "y_ratio": 0.6565, "width_ratio": 0.4081, "height_ratio": 0.0249, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 9}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_133", "display_cluster_candidate_id": "disp_26_0", "layout_region": "display_zone", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 25, "block_id": 24, "raw_label": "reference_content", "raw_order": 22, "bbox": [99, 1048, 585, 1085], "text": "[129] R. Parai, S. Bandyopadhyay-Ghosh, J. Mech. Behav. Biomed. Mater. 2019, 96, 45.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [129] R. Parai, S. Bandyopadhyay-Ghosh, J. Mech. Behav. Biom"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [129] R. Parai, S. Bandyopadhyay-Ghosh, J. Mech. Behav. Biom"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 24, "page": 25, "raw_label": "reference_content", "text": "[129] R. Parai, S. Bandyopadhyay-Ghosh, J. Mech. Behav. Biomed. Mater. 2019, 96, 45.", "bbox": [99, 1048, 585, 1085], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[129]", "number": 129, "kind": "reference", "normalized_text": "[129] R. Parai, S. Bandyopadhyay-Ghosh, J. Mech. Behav. Biomed. Mater. 2019, 96, 45."}, "layout_signature": {"width": 486, "width_bucket": 475, "height": 37, "left": 99, "top": 1048, "right": 585, "bottom": 1085, "x_center": 342.0, "x_center_bucket": 350, "y_center": 1066.5, "x_ratio": 0.2872, "y_ratio": 0.6815, "width_ratio": 0.4081, "height_ratio": 0.0236, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 8}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_134", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 25, "block_id": 25, "raw_label": "reference_content", "raw_order": 23, "bbox": [100, 1088, 584, 1125], "text": "[130] S. S. Lim, C Ye Chai, H.-S. Loh, Mater. Sci. Eng. C Mater. Biol. Appl. 2017, 76, 144.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [130] S. S. Lim, C Ye Chai, H.-S. Loh, Mater. Sci. Eng. C Ma"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [130] S. S. Lim, C Ye Chai, H.-S. Loh, Mater. Sci. Eng. C Ma"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 25, "page": 25, "raw_label": "reference_content", "text": "[130] S. S. Lim, C Ye Chai, H.-S. Loh, Mater. Sci. Eng. C Mater. Biol. Appl. 2017, 76, 144.", "bbox": [100, 1088, 584, 1125], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[130]", "number": 130, "kind": "reference", "normalized_text": "[130] S. S. Lim, C Ye Chai, H.-S. Loh, Mater. Sci. Eng. C Mater. Biol. Appl. 2017, 76, 144."}, "layout_signature": {"width": 484, "width_bucket": 475, "height": 37, "left": 100, "top": 1088, "right": 584, "bottom": 1125, "x_center": 342.0, "x_center_bucket": 350, "y_center": 1106.5, "x_ratio": 0.2872, "y_ratio": 0.707, "width_ratio": 0.4064, "height_ratio": 0.0236, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 8}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_131", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 25, "block_id": 26, "raw_label": "reference_content", "raw_order": 24, "bbox": [100, 1128, 584, 1166], "text": "[131] M. Yazdimamaghani, M. Razavi, D. Vashaee, L. Tayebi, Mater. Sci. Eng. C Mater. Biol. Appl. 2015, 49, 436.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [131] M. Yazdimamaghani, M. Razavi, D. Vashaee, L. Tayebi, M"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [131] M. Yazdimamaghani, M. Razavi, D. Vashaee, L. Tayebi, M"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 26, "page": 25, "raw_label": "reference_content", "text": "[131] M. Yazdimamaghani, M. Razavi, D. Vashaee, L. Tayebi, Mater. Sci. Eng. C Mater. Biol. Appl. 2015, 49, 436.", "bbox": [100, 1128, 584, 1166], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[131]", "number": 131, "kind": "reference", "normalized_text": "[131] M. Yazdimamaghani, M. Razavi, D. Vashaee, L. Tayebi, Mater. Sci. Eng. C Mater. Biol. Appl. 2015, 49, 436."}, "layout_signature": {"width": 484, "width_bucket": 475, "height": 38, "left": 100, "top": 1128, "right": 584, "bottom": 1166, "x_center": 342.0, "x_center_bucket": 350, "y_center": 1147.0, "x_ratio": 0.2872, "y_ratio": 0.7329, "width_ratio": 0.4064, "height_ratio": 0.0243, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 26}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_135", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "hard", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 25, "block_id": 27, "raw_label": "reference_content", "raw_order": 25, "bbox": [99, 1168, 586, 1188], "text": "[132] J. Liu, Q. Fang, X. Yu, Y. Wan, Bo Xiao, Int. J. Mol. Sci. 2018, 19, 2330.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [132] J. Liu, Q. Fang, X. Yu, Y. Wan, Bo Xiao, Int. J. Mol. "], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [132] J. Liu, Q. Fang, X. Yu, Y. Wan, Bo Xiao, Int. J. Mol. "], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 27, "page": 25, "raw_label": "reference_content", "text": "[132] J. Liu, Q. Fang, X. Yu, Y. Wan, Bo Xiao, Int. J. Mol. Sci. 2018, 19, 2330.", "bbox": [99, 1168, 586, 1188], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[132]", "number": 132, "kind": "reference", "normalized_text": "[132] J. Liu, Q. Fang, X. Yu, Y. Wan, Bo Xiao, Int. J. Mol. Sci. 2018, 19, 2330."}, "layout_signature": {"width": 487, "width_bucket": 475, "height": 20, "left": 99, "top": 1168, "right": 586, "bottom": 1188, "x_center": 342.5, "x_center_bucket": 350, "y_center": 1178.0, "x_ratio": 0.2876, "y_ratio": 0.7527, "width_ratio": 0.4089, "height_ratio": 0.0128, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 8}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_137", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 25, "block_id": 28, "raw_label": "reference_content", "raw_order": 26, "bbox": [100, 1188, 547, 1207], "text": "[133] D. Xu, Gu Cheng, J. Dai, Z. Li, Adv Wound Care 2021, 10, 401.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [133] D. Xu, Gu Cheng, J. Dai, Z. Li, Adv Wound Care 2021, 1"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [133] D. Xu, Gu Cheng, J. Dai, Z. Li, Adv Wound Care 2021, 1"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 28, "page": 25, "raw_label": "reference_content", "text": "[133] D. Xu, Gu Cheng, J. Dai, Z. Li, Adv Wound Care 2021, 10, 401.", "bbox": [100, 1188, 547, 1207], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[133]", "number": 133, "kind": "reference", "normalized_text": "[133] D. Xu, Gu Cheng, J. Dai, Z. Li, Adv Wound Care 2021, 10, 401."}, "layout_signature": {"width": 447, "width_bucket": 450, "height": 19, "left": 100, "top": 1188, "right": 547, "bottom": 1207, "x_center": 323.5, "x_center_bucket": 325, "y_center": 1197.5, "x_ratio": 0.2716, "y_ratio": 0.7652, "width_ratio": 0.3753, "height_ratio": 0.0121, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 8}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_137", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 25, "block_id": 29, "raw_label": "reference_content", "raw_order": 27, "bbox": [100, 1208, 585, 1245], "text": "[134] M. Luo, M. Chen, J. Bai, T. Chen, S. He, W. Peng, J. Wang, W. Zhi, J. Weng, Colloids Surf., B 2022, 219, 112821.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [134] M. Luo, M. Chen, J. Bai, T. Chen, S. He, W. Peng, J. W"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [134] M. Luo, M. Chen, J. Bai, T. Chen, S. He, W. Peng, J. W"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 29, "page": 25, "raw_label": "reference_content", "text": "[134] M. Luo, M. Chen, J. Bai, T. Chen, S. He, W. Peng, J. Wang, W. Zhi, J. Weng, Colloids Surf., B 2022, 219, 112821.", "bbox": [100, 1208, 585, 1245], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[134]", "number": 134, "kind": "reference", "normalized_text": "[134] M. Luo, M. Chen, J. Bai, T. Chen, S. He, W. Peng, J. Wang, W. Zhi, J. Weng, Colloids Surf., B 2022, 219, 112821."}, "layout_signature": {"width": 485, "width_bucket": 475, "height": 37, "left": 100, "top": 1208, "right": 585, "bottom": 1245, "x_center": 342.5, "x_center_bucket": 350, "y_center": 1226.5, "x_ratio": 0.2876, "y_ratio": 0.7837, "width_ratio": 0.4072, "height_ratio": 0.0236, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 9}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_126", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 25, "block_id": 30, "raw_label": "reference_content", "raw_order": 28, "bbox": [100, 1247, 586, 1285], "text": "[135] A-Vu Do, B. Khorsand, S. M. Geary, A. K. Salem, Adv. Healthcare Mater. 2015, 4, 1742.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [135] A-Vu Do, B. Khorsand, S. M. Geary, A. K. Salem, Adv. H"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [135] A-Vu Do, B. Khorsand, S. M. Geary, A. K. Salem, Adv. H"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 30, "page": 25, "raw_label": "reference_content", "text": "[135] A-Vu Do, B. Khorsand, S. M. Geary, A. K. Salem, Adv. Healthcare Mater. 2015, 4, 1742.", "bbox": [100, 1247, 586, 1285], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[135]", "number": 135, "kind": "reference", "normalized_text": "[135] A-Vu Do, B. Khorsand, S. M. Geary, A. K. Salem, Adv. Healthcare Mater. 2015, 4, 1742."}, "layout_signature": {"width": 486, "width_bucket": 475, "height": 38, "left": 100, "top": 1247, "right": 586, "bottom": 1285, "x_center": 343.0, "x_center_bucket": 350, "y_center": 1266.0, "x_ratio": 0.288, "y_ratio": 0.8089, "width_ratio": 0.4081, "height_ratio": 0.0243, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 30}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_126", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 25, "block_id": 31, "raw_label": "reference_content", "raw_order": 29, "bbox": [101, 1287, 584, 1326], "text": "[136] J. Babilotte, V. Guduric, D. Le Nihouannen, A. Naveau, J.-C. Fricain, S. Catros, J. Biomed. Mater. Res. B Appl. Biomater. 2019, 107, 2579.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [136] J. Babilotte, V. Guduric, D. Le Nihouannen, A. Naveau,"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [136] J. Babilotte, V. Guduric, D. Le Nihouannen, A. Naveau,"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 31, "page": 25, "raw_label": "reference_content", "text": "[136] J. Babilotte, V. Guduric, D. Le Nihouannen, A. Naveau, J.-C. Fricain, S. Catros, J. Biomed. Mater. Res. B Appl. Biomater. 2019, 107, 2579.", "bbox": [101, 1287, 584, 1326], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[136]", "number": 136, "kind": "reference", "normalized_text": "[136] J. Babilotte, V. Guduric, D. Le Nihouannen, A. Naveau, J.-C. Fricain, S. Catros, J. Biomed. Mater. Res. B Appl. Biomater. 2019, 107, 2579."}, "layout_signature": {"width": 483, "width_bucket": 475, "height": 39, "left": 101, "top": 1287, "right": 584, "bottom": 1326, "x_center": 342.5, "x_center_bucket": 350, "y_center": 1306.5, "x_ratio": 0.2876, "y_ratio": 0.8348, "width_ratio": 0.4055, "height_ratio": 0.0249, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 9}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_126", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 25, "block_id": 32, "raw_label": "reference_content", "raw_order": 30, "bbox": [100, 1327, 584, 1347], "text": "[137] L. Zhang, G. Yang, B. N. Johnson, X. Jia, Acta Biomater. 2019, 84, 16.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [137] L. Zhang, G. Yang, B. N. Johnson, X. Jia, Acta Biomate"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [137] L. Zhang, G. Yang, B. N. Johnson, X. Jia, Acta Biomate"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 32, "page": 25, "raw_label": "reference_content", "text": "[137] L. Zhang, G. Yang, B. N. Johnson, X. Jia, Acta Biomater. 2019, 84, 16.", "bbox": [100, 1327, 584, 1347], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[137]", "number": 137, "kind": "reference", "normalized_text": "[137] L. Zhang, G. Yang, B. N. Johnson, X. Jia, Acta Biomater. 2019, 84, 16."}, "layout_signature": {"width": 484, "width_bucket": 475, "height": 20, "left": 100, "top": 1327, "right": 584, "bottom": 1347, "x_center": 342.0, "x_center_bucket": 350, "y_center": 1337.0, "x_ratio": 0.2872, "y_ratio": 0.8543, "width_ratio": 0.4064, "height_ratio": 0.0128, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 8}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_126", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 25, "block_id": 33, "raw_label": "reference_content", "raw_order": 31, "bbox": [101, 1349, 585, 1404], "text": "[138] A. Kosik-Koziol, E. Graham, J. Jaroszewicz, A. Chlanda, P. T. S Kumar, S. Ivanovski, W. Swieszkowski, C. Vaquette, ACS Biomater. Sci. Eng. 2019, 5, 318.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [138] A. Kosik-Koziol, E. Graham, J. Jaroszewicz, A. Chlanda"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [138] A. Kosik-Koziol, E. Graham, J. Jaroszewicz, A. Chlanda"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 33, "page": 25, "raw_label": "reference_content", "text": "[138] A. Kosik-Koziol, E. Graham, J. Jaroszewicz, A. Chlanda, P. T. S Kumar, S. Ivanovski, W. Swieszkowski, C. Vaquette, ACS Biomater. Sci. Eng. 2019, 5, 318.", "bbox": [101, 1349, 585, 1404], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[138]", "number": 138, "kind": "reference", "normalized_text": "[138] A. Kosik-Koziol, E. Graham, J. Jaroszewicz, A. Chlanda, P. T. S Kumar, S. Ivanovski, W. Swieszkowski, C. Vaquette, ACS Biomater. Sci. Eng. 2019, 5, 318."}, "layout_signature": {"width": 484, "width_bucket": 475, "height": 55, "left": 101, "top": 1349, "right": 585, "bottom": 1404, "x_center": 343.0, "x_center_bucket": 350, "y_center": 1376.5, "x_ratio": 0.288, "y_ratio": 0.8796, "width_ratio": 0.4064, "height_ratio": 0.0351, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 9}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_126", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 25, "block_id": 34, "raw_label": "reference_content", "raw_order": 32, "bbox": [99, 1407, 507, 1426], "text": "[139] W. J. Kim, H.-S. Yun, G. H. Kim, Sci. Rep. 2017, 7, 3181.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [139] W. J. Kim, H.-S. Yun, G. H. Kim, Sci. Rep. 2017, 7, 31"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [139] W. J. Kim, H.-S. Yun, G. H. Kim, Sci. Rep. 2017, 7, 31"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 34, "page": 25, "raw_label": "reference_content", "text": "[139] W. J. Kim, H.-S. Yun, G. H. Kim, Sci. Rep. 2017, 7, 3181.", "bbox": [99, 1407, 507, 1426], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[139]", "number": 139, "kind": "reference", "normalized_text": "[139] W. J. Kim, H.-S. Yun, G. H. Kim, Sci. Rep. 2017, 7, 3181."}, "layout_signature": {"width": 408, "width_bucket": 400, "height": 19, "left": 99, "top": 1407, "right": 507, "bottom": 1426, "x_center": 303.0, "x_center_bucket": 300, "y_center": 1416.5, "x_ratio": 0.2544, "y_ratio": 0.9051, "width_ratio": 0.3426, "height_ratio": 0.0121, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 8}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_124", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 25, "block_id": 35, "raw_label": "reference_content", "raw_order": 33, "bbox": [610, 151, 1095, 188], "text": "[140] J. Huh, J. Lee, W. Kim, M. Yeo, G. Kim, Int. J. Biol. Macromol. 2018, 110, 488.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [140] J. Huh, J. Lee, W. Kim, M. Yeo, G. Kim, Int. J. Biol. "], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [140] J. Huh, J. Lee, W. Kim, M. Yeo, G. Kim, Int. J. Biol. "], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 35, "page": 25, "raw_label": "reference_content", "text": "[140] J. Huh, J. Lee, W. Kim, M. Yeo, G. Kim, Int. J. Biol. Macromol. 2018, 110, 488.", "bbox": [610, 151, 1095, 188], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[140]", "number": 140, "kind": "reference", "normalized_text": "[140] J. Huh, J. Lee, W. Kim, M. Yeo, G. Kim, Int. J. Biol. Macromol. 2018, 110, 488."}, "layout_signature": {"width": 485, "width_bucket": 475, "height": 37, "left": 610, "top": 151, "right": 1095, "bottom": 188, "x_center": 852.5, "x_center_bucket": 850, "y_center": 169.5, "x_ratio": 0.7158, "y_ratio": 0.1083, "width_ratio": 0.4072, "height_ratio": 0.0236, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 8}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_127", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 25, "block_id": 36, "raw_label": "reference_content", "raw_order": 34, "bbox": [610, 191, 1096, 228], "text": "[141] F. Pati, T-Ha Song, G. Rijal, J. Jang, S. W. Kim, D.-W. Cho, Biomaterials 2015, 37, 230.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [141] F. Pati, T-Ha Song, G. Rijal, J. Jang, S. W. Kim, D.-W"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [141] F. Pati, T-Ha Song, G. Rijal, J. Jang, S. W. Kim, D.-W"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 36, "page": 25, "raw_label": "reference_content", "text": "[141] F. Pati, T-Ha Song, G. Rijal, J. Jang, S. W. Kim, D.-W. Cho, Biomaterials 2015, 37, 230.", "bbox": [610, 191, 1096, 228], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[141]", "number": 141, "kind": "reference", "normalized_text": "[141] F. Pati, T-Ha Song, G. Rijal, J. Jang, S. W. Kim, D.-W. Cho, Biomaterials 2015, 37, 230."}, "layout_signature": {"width": 486, "width_bucket": 475, "height": 37, "left": 610, "top": 191, "right": 1096, "bottom": 228, "x_center": 853.0, "x_center_bucket": 850, "y_center": 209.5, "x_ratio": 0.7162, "y_ratio": 0.1339, "width_ratio": 0.4081, "height_ratio": 0.0236, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 8}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_127", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 25, "block_id": 37, "raw_label": "reference_content", "raw_order": 35, "bbox": [610, 231, 1095, 270], "text": "[142] K. F. Lin, S. He, Y. Song, C. M. Wang, Y. Gao, J. Q. Li, P. Tang, Z. Wang, L. Bi, G. X. Pei, ACS Appl. Mater. Interfaces 2016, 8, 6905.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [142] K. F. Lin, S. He, Y. Song, C. M. Wang, Y. Gao, J. Q. L"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [142] K. F. Lin, S. He, Y. Song, C. M. Wang, Y. Gao, J. Q. L"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 37, "page": 25, "raw_label": "reference_content", "text": "[142] K. F. Lin, S. He, Y. Song, C. M. Wang, Y. Gao, J. Q. Li, P. Tang, Z. Wang, L. Bi, G. X. Pei, ACS Appl. Mater. Interfaces 2016, 8, 6905.", "bbox": [610, 231, 1095, 270], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[142]", "number": 142, "kind": "reference", "normalized_text": "[142] K. F. Lin, S. He, Y. Song, C. M. Wang, Y. Gao, J. Q. Li, P. Tang, Z. Wang, L. Bi, G. X. Pei, ACS Appl. Mater. Interfaces 2016, 8, 6905."}, "layout_signature": {"width": 485, "width_bucket": 475, "height": 39, "left": 610, "top": 231, "right": 1095, "bottom": 270, "x_center": 852.5, "x_center_bucket": 850, "y_center": 250.5, "x_ratio": 0.7158, "y_ratio": 0.1601, "width_ratio": 0.4072, "height_ratio": 0.0249, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 43}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_127", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 25, "block_id": 38, "raw_label": "reference_content", "raw_order": 36, "bbox": [610, 271, 1095, 347], "text": "[143] A. E. Jakus, A. L. Rutz, S. W. Jordan, A. Kannan, S. M. Mitchell, C. Yun, K. D. Koube, S. C. Yoo, H. E. Whiteley, C.-P. Richter, R. D. Galiano, W. K. Hsu, S. R. Stock, E. L. Hsu, R. N. Shah, Sci. Transl. Med. 2016, 8, 358ra127.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [143] A. E. Jakus, A. L. Rutz, S. W. Jordan, A. Kannan, S. M"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [143] A. E. Jakus, A. L. Rutz, S. W. Jordan, A. Kannan, S. M"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 38, "page": 25, "raw_label": "reference_content", "text": "[143] A. E. Jakus, A. L. Rutz, S. W. Jordan, A. Kannan, S. M. Mitchell, C. Yun, K. D. Koube, S. C. Yoo, H. E. Whiteley, C.-P. Richter, R. D. Galiano, W. K. Hsu, S. R. Stock, E. L. Hsu, R. N. Shah, Sci. Transl. Med. 2016, 8, 358ra127.", "bbox": [610, 271, 1095, 347], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[143]", "number": 143, "kind": "reference", "normalized_text": "[143] A. E. Jakus, A. L. Rutz, S. W. Jordan, A. Kannan, S. M. Mitchell, C. Yun, K. D. Koube, S. C. Yoo, H. E. Whiteley, C.-P. Richter, R. D. Galiano, W. K. Hsu, S. R. Stock, E. L. Hsu, R. N. Shah, Sci. Transl. Med. 2016, 8, 358ra127."}, "layout_signature": {"width": 485, "width_bucket": 475, "height": 76, "left": 610, "top": 271, "right": 1095, "bottom": 347, "x_center": 852.5, "x_center_bucket": 850, "y_center": 309.0, "x_ratio": 0.7158, "y_ratio": 0.1974, "width_ratio": 0.4072, "height_ratio": 0.0486, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 10}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_127", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 25, "block_id": 39, "raw_label": "reference_content", "raw_order": 37, "bbox": [610, 351, 1095, 389], "text": "[144] W. Wei, W. Liu, H. Kang, X. Zhang, R. Yu, J. Liu, K. Huang, Y. Zhang, M. Xie, Y. Hu, H. Dai, Adv. Healthc. Mater. 2023, 12, 2300108.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [144] W. Wei, W. Liu, H. Kang, X. Zhang, R. Yu, J. Liu, K. H"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [144] W. Wei, W. Liu, H. Kang, X. Zhang, R. Yu, J. Liu, K. H"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 39, "page": 25, "raw_label": "reference_content", "text": "[144] W. Wei, W. Liu, H. Kang, X. Zhang, R. Yu, J. Liu, K. Huang, Y. Zhang, M. Xie, Y. Hu, H. Dai, Adv. Healthc. Mater. 2023, 12, 2300108.", "bbox": [610, 351, 1095, 389], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[144]", "number": 144, "kind": "reference", "normalized_text": "[144] W. Wei, W. Liu, H. Kang, X. Zhang, R. Yu, J. Liu, K. Huang, Y. Zhang, M. Xie, Y. Hu, H. Dai, Adv. Healthc. Mater. 2023, 12, 2300108."}, "layout_signature": {"width": 485, "width_bucket": 475, "height": 38, "left": 610, "top": 351, "right": 1095, "bottom": 389, "x_center": 852.5, "x_center_bucket": 850, "y_center": 370.0, "x_ratio": 0.7158, "y_ratio": 0.2364, "width_ratio": 0.4072, "height_ratio": 0.0243, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 9}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_127", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 25, "block_id": 40, "raw_label": "reference_content", "raw_order": 38, "bbox": [610, 391, 1068, 409], "text": "[145] Z. Li, Y. Zhou, T. Li, J. Zhang, He Tian, View 2021, 3, 20200112.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [145] Z. Li, Y. Zhou, T. Li, J. Zhang, He Tian, View 2021, 3"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [145] Z. Li, Y. Zhou, T. Li, J. Zhang, He Tian, View 2021, 3"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 40, "page": 25, "raw_label": "reference_content", "text": "[145] Z. Li, Y. Zhou, T. Li, J. Zhang, He Tian, View 2021, 3, 20200112.", "bbox": [610, 391, 1068, 409], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[145]", "number": 145, "kind": "reference", "normalized_text": "[145] Z. Li, Y. Zhou, T. Li, J. Zhang, He Tian, View 2021, 3, 20200112."}, "layout_signature": {"width": 458, "width_bucket": 450, "height": 18, "left": 610, "top": 391, "right": 1068, "bottom": 409, "x_center": 839.0, "x_center_bucket": 850, "y_center": 400.0, "x_ratio": 0.7045, "y_ratio": 0.2556, "width_ratio": 0.3846, "height_ratio": 0.0115, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 8}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_127", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 25, "block_id": 41, "raw_label": "reference_content", "raw_order": 39, "bbox": [610, 410, 1004, 429], "text": "[146] J. Liao, R. Han, Y. Wu, Z. Qian, Bone Res. 2021, 9, 18.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [146] J. Liao, R. Han, Y. Wu, Z. Qian, Bone Res. 2021, 9, 18"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [146] J. Liao, R. Han, Y. Wu, Z. Qian, Bone Res. 2021, 9, 18"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 41, "page": 25, "raw_label": "reference_content", "text": "[146] J. Liao, R. Han, Y. Wu, Z. Qian, Bone Res. 2021, 9, 18.", "bbox": [610, 410, 1004, 429], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[146]", "number": 146, "kind": "reference", "normalized_text": "[146] J. Liao, R. Han, Y. Wu, Z. Qian, Bone Res. 2021, 9, 18."}, "layout_signature": {"width": 394, "width_bucket": 400, "height": 19, "left": 610, "top": 410, "right": 1004, "bottom": 429, "x_center": 807.0, "x_center_bucket": 800, "y_center": 419.5, "x_ratio": 0.6776, "y_ratio": 0.2681, "width_ratio": 0.3308, "height_ratio": 0.0121, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 8}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_127", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 25, "block_id": 42, "raw_label": "reference_content", "raw_order": 40, "bbox": [610, 430, 1095, 467], "text": "[147] L. Tong, Q. Liao, Y. Zhao, H. Huang, A. Gao, W. Zhang, X. Gao, W. Wei, M. Guan, P. K. Chu, H. Wang, Biomaterials 2019, 193, 1.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [147] L. Tong, Q. Liao, Y. Zhao, H. Huang, A. Gao, W. Zhang,"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [147] L. Tong, Q. Liao, Y. Zhao, H. Huang, A. Gao, W. Zhang,"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 42, "page": 25, "raw_label": "reference_content", "text": "[147] L. Tong, Q. Liao, Y. Zhao, H. Huang, A. Gao, W. Zhang, X. Gao, W. Wei, M. Guan, P. K. Chu, H. Wang, Biomaterials 2019, 193, 1.", "bbox": [610, 430, 1095, 467], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[147]", "number": 147, "kind": "reference", "normalized_text": "[147] L. Tong, Q. Liao, Y. Zhao, H. Huang, A. Gao, W. Zhang, X. Gao, W. Wei, M. Guan, P. K. Chu, H. Wang, Biomaterials 2019, 193, 1."}, "layout_signature": {"width": 485, "width_bucket": 475, "height": 37, "left": 610, "top": 430, "right": 1095, "bottom": 467, "x_center": 852.5, "x_center_bucket": 850, "y_center": 448.5, "x_ratio": 0.7158, "y_ratio": 0.2866, "width_ratio": 0.4072, "height_ratio": 0.0236, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 9}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_127", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 25, "block_id": 43, "raw_label": "reference_content", "raw_order": 41, "bbox": [610, 470, 1096, 527], "text": "[148] X. Wang, J. Shao, M. Abd El Raouf, H. Xie, H. Huang, H. Wang, P. K. Chu, X.-F. Yu, Y. Yang, A. M. Abdel-Aal, N. H. M. Mekkawy, R. J. Miron, Y. Zhang, Biomaterials 2018, 179, 164.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [148] X. Wang, J. Shao, M. Abd El Raouf, H. Xie, H. Huang, H"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [148] X. Wang, J. Shao, M. Abd El Raouf, H. Xie, H. Huang, H"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 43, "page": 25, "raw_label": "reference_content", "text": "[148] X. Wang, J. Shao, M. Abd El Raouf, H. Xie, H. Huang, H. Wang, P. K. Chu, X.-F. Yu, Y. Yang, A. M. Abdel-Aal, N. H. M. Mekkawy, R. J. Miron, Y. Zhang, Biomaterials 2018, 179, 164.", "bbox": [610, 470, 1096, 527], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[148]", "number": 148, "kind": "reference", "normalized_text": "[148] X. Wang, J. Shao, M. Abd El Raouf, H. Xie, H. Huang, H. Wang, P. K. Chu, X.-F. Yu, Y. Yang, A. M. Abdel-Aal, N. H. M. Mekkawy, R. J. Miron, Y. Zhang, Biomaterials 2018, 179, 164."}, "layout_signature": {"width": 486, "width_bucket": 475, "height": 57, "left": 610, "top": 470, "right": 1096, "bottom": 527, "x_center": 853.0, "x_center_bucket": 850, "y_center": 498.5, "x_ratio": 0.7162, "y_ratio": 0.3185, "width_ratio": 0.4081, "height_ratio": 0.0364, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 10}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_127", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 25, "block_id": 44, "raw_label": "reference_content", "raw_order": 42, "bbox": [610, 530, 1095, 568], "text": "[149] L. Ma, X. Feng, H. Liang, K. Wang, Yu Song, L. Tan, B. Wang, R. Luo, Z. Liao, G. Li, X. Liu, S. Wu, C. Yang, Mater. Today 2020, 36, 48.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [149] L. Ma, X. Feng, H. Liang, K. Wang, Yu Song, L. Tan, B."], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [149] L. Ma, X. Feng, H. Liang, K. Wang, Yu Song, L. Tan, B."], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 44, "page": 25, "raw_label": "reference_content", "text": "[149] L. Ma, X. Feng, H. Liang, K. Wang, Yu Song, L. Tan, B. Wang, R. Luo, Z. Liao, G. Li, X. Liu, S. Wu, C. Yang, Mater. Today 2020, 36, 48.", "bbox": [610, 530, 1095, 568], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[149]", "number": 149, "kind": "reference", "normalized_text": "[149] L. Ma, X. Feng, H. Liang, K. Wang, Yu Song, L. Tan, B. Wang, R. Luo, Z. Liao, G. Li, X. Liu, S. Wu, C. Yang, Mater. Today 2020, 36, 48."}, "layout_signature": {"width": 485, "width_bucket": 475, "height": 38, "left": 610, "top": 530, "right": 1095, "bottom": 568, "x_center": 852.5, "x_center_bucket": 850, "y_center": 549.0, "x_ratio": 0.7158, "y_ratio": 0.3508, "width_ratio": 0.4072, "height_ratio": 0.0243, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 9}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_127", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 25, "block_id": 45, "raw_label": "reference_content", "raw_order": 43, "bbox": [610, 570, 1096, 608], "text": "[150] L. Leppik, K. M. C. Oliveira, M. B. Bhavsar, J. H. Barker, Eur. J. Trauma Emerg. Surg. 2020, 46, 231.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [150] L. Leppik, K. M. C. Oliveira, M. B. Bhavsar, J. H. Bar"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [150] L. Leppik, K. M. C. Oliveira, M. B. Bhavsar, J. H. Bar"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 45, "page": 25, "raw_label": "reference_content", "text": "[150] L. Leppik, K. M. C. Oliveira, M. B. Bhavsar, J. H. Barker, Eur. J. Trauma Emerg. Surg. 2020, 46, 231.", "bbox": [610, 570, 1096, 608], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[150]", "number": 150, "kind": "reference", "normalized_text": "[150] L. Leppik, K. M. C. Oliveira, M. B. Bhavsar, J. H. Barker, Eur. J. Trauma Emerg. Surg. 2020, 46, 231."}, "layout_signature": {"width": 486, "width_bucket": 475, "height": 38, "left": 610, "top": 570, "right": 1096, "bottom": 608, "x_center": 853.0, "x_center_bucket": 850, "y_center": 589.0, "x_ratio": 0.7162, "y_ratio": 0.3764, "width_ratio": 0.4081, "height_ratio": 0.0243, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 9}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_127", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 25, "block_id": 46, "raw_label": "reference_content", "raw_order": 44, "bbox": [610, 610, 1095, 647], "text": "[151] B. Zhu, Y. Li, F. Huang, Z. Chen, J. Xie, C. Ding, J. Li, Biomater. Sci. 2019, 7, 4730.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [151] B. Zhu, Y. Li, F. Huang, Z. Chen, J. Xie, C. Ding, J. "], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [151] B. Zhu, Y. Li, F. Huang, Z. Chen, J. Xie, C. Ding, J. "], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 46, "page": 25, "raw_label": "reference_content", "text": "[151] B. Zhu, Y. Li, F. Huang, Z. Chen, J. Xie, C. Ding, J. Li, Biomater. Sci. 2019, 7, 4730.", "bbox": [610, 610, 1095, 647], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[151]", "number": 151, "kind": "reference", "normalized_text": "[151] B. Zhu, Y. Li, F. Huang, Z. Chen, J. Xie, C. Ding, J. Li, Biomater. Sci. 2019, 7, 4730."}, "layout_signature": {"width": 485, "width_bucket": 475, "height": 37, "left": 610, "top": 610, "right": 1095, "bottom": 647, "x_center": 852.5, "x_center_bucket": 850, "y_center": 628.5, "x_ratio": 0.7158, "y_ratio": 0.4016, "width_ratio": 0.4072, "height_ratio": 0.0236, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 8}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_127", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 25, "block_id": 47, "raw_label": "reference_content", "raw_order": 45, "bbox": [610, 650, 1096, 688], "text": "[152] T. Zhou, L. Yan, C. Xie, P. Li, L. Jiang, Ju Fang, C. Zhao, F. Ren, K. Wang, Y. Wang, H. Zhang, T. Guo, X. Lu, Small 2019, 15, e1805440.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [152] T. Zhou, L. Yan, C. Xie, P. Li, L. Jiang, Ju Fang, C. "], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [152] T. Zhou, L. Yan, C. Xie, P. Li, L. Jiang, Ju Fang, C. "], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 47, "page": 25, "raw_label": "reference_content", "text": "[152] T. Zhou, L. Yan, C. Xie, P. Li, L. Jiang, Ju Fang, C. Zhao, F. Ren, K. Wang, Y. Wang, H. Zhang, T. Guo, X. Lu, Small 2019, 15, e1805440.", "bbox": [610, 650, 1096, 688], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[152]", "number": 152, "kind": "reference", "normalized_text": "[152] T. Zhou, L. Yan, C. Xie, P. Li, L. Jiang, Ju Fang, C. Zhao, F. Ren, K. Wang, Y. Wang, H. Zhang, T. Guo, X. Lu, Small 2019, 15, e1805440."}, "layout_signature": {"width": 486, "width_bucket": 475, "height": 38, "left": 610, "top": 650, "right": 1096, "bottom": 688, "x_center": 853.0, "x_center_bucket": 850, "y_center": 669.0, "x_ratio": 0.7162, "y_ratio": 0.4275, "width_ratio": 0.4081, "height_ratio": 0.0243, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 41}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_127", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 25, "block_id": 48, "raw_label": "reference_content", "raw_order": 46, "bbox": [611, 689, 1095, 727], "text": "[153] H. Yan, L. Li, Yu Wang, J. Huang, Z. Wang, X. Shi, P. Zhang, New J. Chem. 2019, 43, 17315.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [153] H. Yan, L. Li, Yu Wang, J. Huang, Z. Wang, X. Shi, P. "], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [153] H. Yan, L. Li, Yu Wang, J. Huang, Z. Wang, X. Shi, P. "], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 48, "page": 25, "raw_label": "reference_content", "text": "[153] H. Yan, L. Li, Yu Wang, J. Huang, Z. Wang, X. Shi, P. Zhang, New J. Chem. 2019, 43, 17315.", "bbox": [611, 689, 1095, 727], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[153]", "number": 153, "kind": "reference", "normalized_text": "[153] H. Yan, L. Li, Yu Wang, J. Huang, Z. Wang, X. Shi, P. Zhang, New J. Chem. 2019, 43, 17315."}, "layout_signature": {"width": 484, "width_bucket": 475, "height": 38, "left": 611, "top": 689, "right": 1095, "bottom": 727, "x_center": 853.0, "x_center_bucket": 850, "y_center": 708.0, "x_ratio": 0.7162, "y_ratio": 0.4524, "width_ratio": 0.4064, "height_ratio": 0.0243, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 9}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_127", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 25, "block_id": 49, "raw_label": "reference_content", "raw_order": 47, "bbox": [595, 730, 1111, 769], "text": "[154] B. Chen, H. Xiang, S. Pan, L. Yu, T. Xu, Yu Chen, Adv. Funct. Mater. 2020, 30, 2002621.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [154] B. Chen, H. Xiang, S. Pan, L. Yu, T. Xu, Yu Chen, Adv."], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [154] B. Chen, H. Xiang, S. Pan, L. Yu, T. Xu, Yu Chen, Adv."], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 49, "page": 25, "raw_label": "reference_content", "text": "[154] B. Chen, H. Xiang, S. Pan, L. Yu, T. Xu, Yu Chen, Adv. Funct. Mater. 2020, 30, 2002621.", "bbox": [595, 730, 1111, 769], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[154]", "number": 154, "kind": "reference", "normalized_text": "[154] B. Chen, H. Xiang, S. Pan, L. Yu, T. Xu, Yu Chen, Adv. Funct. Mater. 2020, 30, 2002621."}, "layout_signature": {"width": 516, "width_bucket": 525, "height": 39, "left": 595, "top": 730, "right": 1111, "bottom": 769, "x_center": 853.0, "x_center_bucket": 850, "y_center": 749.5, "x_ratio": 0.7162, "y_ratio": 0.4789, "width_ratio": 0.4332, "height_ratio": 0.0249, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 8}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_126", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 25, "block_id": 50, "raw_label": "reference_content", "raw_order": 48, "bbox": [610, 769, 1096, 807], "text": "[155] Z. Cao, D. Wang, Y. Li, W. Xie, X. Wang, L. Tao, Y. Wei, X. Wang, L. Zhao, Sci. China. Life Sci. 2018, 61, 448.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [155] Z. Cao, D. Wang, Y. Li, W. Xie, X. Wang, L. Tao, Y. We"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [155] Z. Cao, D. Wang, Y. Li, W. Xie, X. Wang, L. Tao, Y. We"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 50, "page": 25, "raw_label": "reference_content", "text": "[155] Z. Cao, D. Wang, Y. Li, W. Xie, X. Wang, L. Tao, Y. Wei, X. Wang, L. Zhao, Sci. China. Life Sci. 2018, 61, 448.", "bbox": [610, 769, 1096, 807], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[155]", "number": 155, "kind": "reference", "normalized_text": "[155] Z. Cao, D. Wang, Y. Li, W. Xie, X. Wang, L. Tao, Y. Wei, X. Wang, L. Zhao, Sci. China. Life Sci. 2018, 61, 448."}, "layout_signature": {"width": 486, "width_bucket": 475, "height": 38, "left": 610, "top": 769, "right": 1096, "bottom": 807, "x_center": 853.0, "x_center_bucket": 850, "y_center": 788.0, "x_ratio": 0.7162, "y_ratio": 0.5035, "width_ratio": 0.4081, "height_ratio": 0.0243, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 9}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_127", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 25, "block_id": 51, "raw_label": "reference_content", "raw_order": 49, "bbox": [610, 809, 1096, 846], "text": "[156] S. Dong, Yu Chen, L. Yu, K. Lin, X. Wang, Adv. Funct. Mater. 2020, 30, 1907071.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [156] S. Dong, Yu Chen, L. Yu, K. Lin, X. Wang, Adv. Funct. "], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [156] S. Dong, Yu Chen, L. Yu, K. Lin, X. Wang, Adv. Funct. "], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 51, "page": 25, "raw_label": "reference_content", "text": "[156] S. Dong, Yu Chen, L. Yu, K. Lin, X. Wang, Adv. Funct. Mater. 2020, 30, 1907071.", "bbox": [610, 809, 1096, 846], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[156]", "number": 156, "kind": "reference", "normalized_text": "[156] S. Dong, Yu Chen, L. Yu, K. Lin, X. Wang, Adv. Funct. Mater. 2020, 30, 1907071."}, "layout_signature": {"width": 486, "width_bucket": 475, "height": 37, "left": 610, "top": 809, "right": 1096, "bottom": 846, "x_center": 853.0, "x_center_bucket": 850, "y_center": 827.5, "x_ratio": 0.7162, "y_ratio": 0.5288, "width_ratio": 0.4081, "height_ratio": 0.0236, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 32}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_127", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 25, "block_id": 52, "raw_label": "reference_content", "raw_order": 50, "bbox": [610, 849, 1097, 887], "text": "[157] F. Yan, Z. Liu, T. Zhang, Qi Zhang, Y. Chen, Y. Xie, J. Lei, L. Cai, ACS Biomater. Sci. Eng. 2019, 5, 5833.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [157] F. Yan, Z. Liu, T. Zhang, Qi Zhang, Y. Chen, Y. Xie, J"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [157] F. Yan, Z. Liu, T. Zhang, Qi Zhang, Y. Chen, Y. Xie, J"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 52, "page": 25, "raw_label": "reference_content", "text": "[157] F. Yan, Z. Liu, T. Zhang, Qi Zhang, Y. Chen, Y. Xie, J. Lei, L. Cai, ACS Biomater. Sci. Eng. 2019, 5, 5833.", "bbox": [610, 849, 1097, 887], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[157]", "number": 157, "kind": "reference", "normalized_text": "[157] F. Yan, Z. Liu, T. Zhang, Qi Zhang, Y. Chen, Y. Xie, J. Lei, L. Cai, ACS Biomater. Sci. Eng. 2019, 5, 5833."}, "layout_signature": {"width": 487, "width_bucket": 475, "height": 38, "left": 610, "top": 849, "right": 1097, "bottom": 887, "x_center": 853.5, "x_center_bucket": 850, "y_center": 868.0, "x_ratio": 0.7166, "y_ratio": 0.5546, "width_ratio": 0.4089, "height_ratio": 0.0243, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 9}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_127", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 25, "block_id": 53, "raw_label": "reference_content", "raw_order": 51, "bbox": [610, 889, 1096, 927], "text": "[158] Bo Fan, Z. Guo, X. Li, S. Li, P. Gao, X. Xiao, J. Wu, C. Shen, Y. Jiao, W. Hou, Bioact. Mater. 2020, 5, 1087.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [158] Bo Fan, Z. Guo, X. Li, S. Li, P. Gao, X. Xiao, J. Wu, "], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [158] Bo Fan, Z. Guo, X. Li, S. Li, P. Gao, X. Xiao, J. Wu, "], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 53, "page": 25, "raw_label": "reference_content", "text": "[158] Bo Fan, Z. Guo, X. Li, S. Li, P. Gao, X. Xiao, J. Wu, C. Shen, Y. Jiao, W. Hou, Bioact. Mater. 2020, 5, 1087.", "bbox": [610, 889, 1096, 927], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[158]", "number": 158, "kind": "reference", "normalized_text": "[158] Bo Fan, Z. Guo, X. Li, S. Li, P. Gao, X. Xiao, J. Wu, C. Shen, Y. Jiao, W. Hou, Bioact. Mater. 2020, 5, 1087."}, "layout_signature": {"width": 486, "width_bucket": 475, "height": 38, "left": 610, "top": 889, "right": 1096, "bottom": 927, "x_center": 853.0, "x_center_bucket": 850, "y_center": 908.0, "x_ratio": 0.7162, "y_ratio": 0.5802, "width_ratio": 0.4081, "height_ratio": 0.0243, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 9}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_127", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 25, "block_id": 54, "raw_label": "reference_content", "raw_order": 52, "bbox": [610, 930, 1096, 985], "text": "[159] G. J. Crasto, N. Kartner, N. Reznik, M. V. Spatafora, H. Chen, R. Williams, P. N. Burns, C. Clokie, M. F. Manolson, S. A. F. Peel, J. Control. Release 2016, 243, 99.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [159] G. J. Crasto, N. Kartner, N. Reznik, M. V. Spatafora, "], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [159] G. J. Crasto, N. Kartner, N. Reznik, M. V. Spatafora, "], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 54, "page": 25, "raw_label": "reference_content", "text": "[159] G. J. Crasto, N. Kartner, N. Reznik, M. V. Spatafora, H. Chen, R. Williams, P. N. Burns, C. Clokie, M. F. Manolson, S. A. F. Peel, J. Control. Release 2016, 243, 99.", "bbox": [610, 930, 1096, 985], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[159]", "number": 159, "kind": "reference", "normalized_text": "[159] G. J. Crasto, N. Kartner, N. Reznik, M. V. Spatafora, H. Chen, R. Williams, P. N. Burns, C. Clokie, M. F. Manolson, S. A. F. Peel, J. Control. Release 2016, 243, 99."}, "layout_signature": {"width": 486, "width_bucket": 475, "height": 55, "left": 610, "top": 930, "right": 1096, "bottom": 985, "x_center": 853.0, "x_center_bucket": 850, "y_center": 957.5, "x_ratio": 0.7162, "y_ratio": 0.6118, "width_ratio": 0.4081, "height_ratio": 0.0351, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 59}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_127", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 25, "block_id": 55, "raw_label": "reference_content", "raw_order": 53, "bbox": [610, 988, 1095, 1026], "text": "[160] K. Su, L. Tan, X. Liu, Z. Cui, Y. Zheng, Bo Li, Y. Han, Z. Li, S. Zhu, Y. Liang, X. Feng, X. Wang, S. Wu, ACS Nano 2020, 14, 2077.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [160] K. Su, L. Tan, X. Liu, Z. Cui, Y. Zheng, Bo Li, Y. Han"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [160] K. Su, L. Tan, X. Liu, Z. Cui, Y. Zheng, Bo Li, Y. Han"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 55, "page": 25, "raw_label": "reference_content", "text": "[160] K. Su, L. Tan, X. Liu, Z. Cui, Y. Zheng, Bo Li, Y. Han, Z. Li, S. Zhu, Y. Liang, X. Feng, X. Wang, S. Wu, ACS Nano 2020, 14, 2077.", "bbox": [610, 988, 1095, 1026], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[160]", "number": 160, "kind": "reference", "normalized_text": "[160] K. Su, L. Tan, X. Liu, Z. Cui, Y. Zheng, Bo Li, Y. Han, Z. Li, S. Zhu, Y. Liang, X. Feng, X. Wang, S. Wu, ACS Nano 2020, 14, 2077."}, "layout_signature": {"width": 485, "width_bucket": 475, "height": 38, "left": 610, "top": 988, "right": 1095, "bottom": 1026, "x_center": 852.5, "x_center_bucket": 850, "y_center": 1007.0, "x_ratio": 0.7158, "y_ratio": 0.6435, "width_ratio": 0.4072, "height_ratio": 0.0243, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 9}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_127", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 25, "block_id": 56, "raw_label": "reference_content", "raw_order": 54, "bbox": [610, 1028, 1096, 1066], "text": "[161] D. Kim, S. A. Han, J Ho Kim, J.-H. Lee, S.-W. Kim, S.-W. Lee, Adv. Mater. 2020, 32, 1906989.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [161] D. Kim, S. A. Han, J Ho Kim, J.-H. Lee, S.-W. Kim, S.-"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [161] D. Kim, S. A. Han, J Ho Kim, J.-H. Lee, S.-W. Kim, S.-"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 56, "page": 25, "raw_label": "reference_content", "text": "[161] D. Kim, S. A. Han, J Ho Kim, J.-H. Lee, S.-W. Kim, S.-W. Lee, Adv. Mater. 2020, 32, 1906989.", "bbox": [610, 1028, 1096, 1066], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[161]", "number": 161, "kind": "reference", "normalized_text": "[161] D. Kim, S. A. Han, J Ho Kim, J.-H. Lee, S.-W. Kim, S.-W. Lee, Adv. Mater. 2020, 32, 1906989."}, "layout_signature": {"width": 486, "width_bucket": 475, "height": 38, "left": 610, "top": 1028, "right": 1096, "bottom": 1066, "x_center": 853.0, "x_center_bucket": 850, "y_center": 1047.0, "x_ratio": 0.7162, "y_ratio": 0.669, "width_ratio": 0.4081, "height_ratio": 0.0243, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 36}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_127", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 25, "block_id": 57, "raw_label": "reference_content", "raw_order": 55, "bbox": [610, 1068, 1096, 1104], "text": "[162] Y. Tang, C. Wu, Z. Wu, L. Hu, W. Zhang, K. Zhao, Sci. Rep. 2017, 7, 43360.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [162] Y. Tang, C. Wu, Z. Wu, L. Hu, W. Zhang, K. Zhao, Sci. "], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [162] Y. Tang, C. Wu, Z. Wu, L. Hu, W. Zhang, K. Zhao, Sci. "], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 57, "page": 25, "raw_label": "reference_content", "text": "[162] Y. Tang, C. Wu, Z. Wu, L. Hu, W. Zhang, K. Zhao, Sci. Rep. 2017, 7, 43360.", "bbox": [610, 1068, 1096, 1104], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[162]", "number": 162, "kind": "reference", "normalized_text": "[162] Y. Tang, C. Wu, Z. Wu, L. Hu, W. Zhang, K. Zhao, Sci. Rep. 2017, 7, 43360."}, "layout_signature": {"width": 486, "width_bucket": 475, "height": 36, "left": 610, "top": 1068, "right": 1096, "bottom": 1104, "x_center": 853.0, "x_center_bucket": 850, "y_center": 1086.0, "x_ratio": 0.7162, "y_ratio": 0.6939, "width_ratio": 0.4081, "height_ratio": 0.023, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 9}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_127", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 25, "block_id": 58, "raw_label": "reference_content", "raw_order": 56, "bbox": [610, 1108, 1096, 1147], "text": "[163] Y. Bai, X. Dai, Y. Yin, J. Wang, X. Sun, W. Liang, Y. Li, X. Deng, X. Zhang, Int. J. Nanomed. 2019, 14, 3015.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [163] Y. Bai, X. Dai, Y. Yin, J. Wang, X. Sun, W. Liang, Y. "], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [163] Y. Bai, X. Dai, Y. Yin, J. Wang, X. Sun, W. Liang, Y. "], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 58, "page": 25, "raw_label": "reference_content", "text": "[163] Y. Bai, X. Dai, Y. Yin, J. Wang, X. Sun, W. Liang, Y. Li, X. Deng, X. Zhang, Int. J. Nanomed. 2019, 14, 3015.", "bbox": [610, 1108, 1096, 1147], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[163]", "number": 163, "kind": "reference", "normalized_text": "[163] Y. Bai, X. Dai, Y. Yin, J. Wang, X. Sun, W. Liang, Y. Li, X. Deng, X. Zhang, Int. J. Nanomed. 2019, 14, 3015."}, "layout_signature": {"width": 486, "width_bucket": 475, "height": 39, "left": 610, "top": 1108, "right": 1096, "bottom": 1147, "x_center": 853.0, "x_center_bucket": 850, "y_center": 1127.5, "x_ratio": 0.7162, "y_ratio": 0.7204, "width_ratio": 0.4081, "height_ratio": 0.0249, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 41}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_127", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 25, "block_id": 59, "raw_label": "reference_content", "raw_order": 57, "bbox": [610, 1148, 1096, 1185], "text": "[164] F. Zhao, C. Zhang, J. Liu, Lu Liu, X. Cao, X. Chen, Bo Lei, L. Shao, Chem. Eng. J. 2020, 402, 126203.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [164] F. Zhao, C. Zhang, J. Liu, Lu Liu, X. Cao, X. Chen, Bo"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [164] F. Zhao, C. Zhang, J. Liu, Lu Liu, X. Cao, X. Chen, Bo"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 59, "page": 25, "raw_label": "reference_content", "text": "[164] F. Zhao, C. Zhang, J. Liu, Lu Liu, X. Cao, X. Chen, Bo Lei, L. Shao, Chem. Eng. J. 2020, 402, 126203.", "bbox": [610, 1148, 1096, 1185], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[164]", "number": 164, "kind": "reference", "normalized_text": "[164] F. Zhao, C. Zhang, J. Liu, Lu Liu, X. Cao, X. Chen, Bo Lei, L. Shao, Chem. Eng. J. 2020, 402, 126203."}, "layout_signature": {"width": 486, "width_bucket": 475, "height": 37, "left": 610, "top": 1148, "right": 1096, "bottom": 1185, "x_center": 853.0, "x_center_bucket": 850, "y_center": 1166.5, "x_ratio": 0.7162, "y_ratio": 0.7454, "width_ratio": 0.4081, "height_ratio": 0.0236, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 38}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_127", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 25, "block_id": 60, "raw_label": "reference_content", "raw_order": 58, "bbox": [610, 1188, 1096, 1225], "text": "[165] G. Li, Z. Li, Y. Min, S. Chen, R. Han, Z. Zhao, Small 2023, 19, e2302927.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [165] G. Li, Z. Li, Y. Min, S. Chen, R. Han, Z. Zhao, Small "], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [165] G. Li, Z. Li, Y. Min, S. Chen, R. Han, Z. Zhao, Small "], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 60, "page": 25, "raw_label": "reference_content", "text": "[165] G. Li, Z. Li, Y. Min, S. Chen, R. Han, Z. Zhao, Small 2023, 19, e2302927.", "bbox": [610, 1188, 1096, 1225], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[165]", "number": 165, "kind": "reference", "normalized_text": "[165] G. Li, Z. Li, Y. Min, S. Chen, R. Han, Z. Zhao, Small 2023, 19, e2302927."}, "layout_signature": {"width": 486, "width_bucket": 475, "height": 37, "left": 610, "top": 1188, "right": 1096, "bottom": 1225, "x_center": 853.0, "x_center_bucket": 850, "y_center": 1206.5, "x_ratio": 0.7162, "y_ratio": 0.7709, "width_ratio": 0.4081, "height_ratio": 0.0236, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 34}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_127", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 25, "block_id": 61, "raw_label": "reference_content", "raw_order": 59, "bbox": [610, 1228, 1095, 1265], "text": "[166] Z. Dong, Y. Lin, S. Xu, L. Chang, X. Zhao, X. Mei, X. Gao, Mater. Design 2023, 225, 111487.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [166] Z. Dong, Y. Lin, S. Xu, L. Chang, X. Zhao, X. Mei, X. "], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [166] Z. Dong, Y. Lin, S. Xu, L. Chang, X. Zhao, X. Mei, X. "], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 61, "page": 25, "raw_label": "reference_content", "text": "[166] Z. Dong, Y. Lin, S. Xu, L. Chang, X. Zhao, X. Mei, X. Gao, Mater. Design 2023, 225, 111487.", "bbox": [610, 1228, 1095, 1265], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[166]", "number": 166, "kind": "reference", "normalized_text": "[166] Z. Dong, Y. Lin, S. Xu, L. Chang, X. Zhao, X. Mei, X. Gao, Mater. Design 2023, 225, 111487."}, "layout_signature": {"width": 485, "width_bucket": 475, "height": 37, "left": 610, "top": 1228, "right": 1095, "bottom": 1265, "x_center": 852.5, "x_center_bucket": 850, "y_center": 1246.5, "x_ratio": 0.7158, "y_ratio": 0.7965, "width_ratio": 0.4072, "height_ratio": 0.0236, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 36}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_127", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 25, "block_id": 62, "raw_label": "reference_content", "raw_order": 60, "bbox": [610, 1267, 1096, 1305], "text": "[167] V. Rao, Yu-Ru V. Shih, H. Kang, H. Kabra, S. Varghese, Front. Bioeng. Biotechnol. 2015, 3, 185.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [167] V. Rao, Yu-Ru V. Shih, H. Kang, H. Kabra, S. Varghese,"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [167] V. Rao, Yu-Ru V. Shih, H. Kang, H. Kabra, S. Varghese,"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 62, "page": 25, "raw_label": "reference_content", "text": "[167] V. Rao, Yu-Ru V. Shih, H. Kang, H. Kabra, S. Varghese, Front. Bioeng. Biotechnol. 2015, 3, 185.", "bbox": [610, 1267, 1096, 1305], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[167]", "number": 167, "kind": "reference", "normalized_text": "[167] V. Rao, Yu-Ru V. Shih, H. Kang, H. Kabra, S. Varghese, Front. Bioeng. Biotechnol. 2015, 3, 185."}, "layout_signature": {"width": 486, "width_bucket": 475, "height": 38, "left": 610, "top": 1267, "right": 1096, "bottom": 1305, "x_center": 853.0, "x_center_bucket": 850, "y_center": 1286.0, "x_ratio": 0.7162, "y_ratio": 0.8217, "width_ratio": 0.4081, "height_ratio": 0.0243, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 9}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_127", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 25, "block_id": 63, "raw_label": "reference_content", "raw_order": 61, "bbox": [611, 1308, 1096, 1363], "text": "[168] Y. Kang, A. I. Georgiou, R. J. Macfarlane, M. E. Klontzas, M. Heliotis, E. Tsiridis, A. Mantalaris, J. Tissue Eng. Regener. Med. 2017, 11, 1929.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [168] Y. Kang, A. I. Georgiou, R. J. Macfarlane, M. E. Klont"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [168] Y. Kang, A. I. Georgiou, R. J. Macfarlane, M. E. Klont"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 63, "page": 25, "raw_label": "reference_content", "text": "[168] Y. Kang, A. I. Georgiou, R. J. Macfarlane, M. E. Klontzas, M. Heliotis, E. Tsiridis, A. Mantalaris, J. Tissue Eng. Regener. Med. 2017, 11, 1929.", "bbox": [611, 1308, 1096, 1363], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[168]", "number": 168, "kind": "reference", "normalized_text": "[168] Y. Kang, A. I. Georgiou, R. J. Macfarlane, M. E. Klontzas, M. Heliotis, E. Tsiridis, A. Mantalaris, J. Tissue Eng. Regener. Med. 2017, 11, 1929."}, "layout_signature": {"width": 485, "width_bucket": 475, "height": 55, "left": 611, "top": 1308, "right": 1096, "bottom": 1363, "x_center": 853.5, "x_center_bucket": 850, "y_center": 1335.5, "x_ratio": 0.7166, "y_ratio": 0.8534, "width_ratio": 0.4072, "height_ratio": 0.0351, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 27}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_127", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 25, "block_id": 64, "raw_label": "reference_content", "raw_order": 62, "bbox": [611, 1367, 922, 1385], "text": "[169] X. Lou, Stem cell Rev. Rep. 2015, 11, 645.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [169] X. Lou, Stem cell Rev. Rep. 2015, 11, 645."], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [169] X. Lou, Stem cell Rev. Rep. 2015, 11, 645."], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 64, "page": 25, "raw_label": "reference_content", "text": "[169] X. Lou, Stem cell Rev. Rep. 2015, 11, 645.", "bbox": [611, 1367, 922, 1385], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[169]", "number": 169, "kind": "reference", "normalized_text": "[169] X. Lou, Stem cell Rev. Rep. 2015, 11, 645."}, "layout_signature": {"width": 311, "width_bucket": 300, "height": 18, "left": 611, "top": 1367, "right": 922, "bottom": 1385, "x_center": 766.5, "x_center_bucket": 775, "y_center": 1376.0, "x_ratio": 0.6436, "y_ratio": 0.8792, "width_ratio": 0.2611, "height_ratio": 0.0115, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 8}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_127", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 25, "block_id": 65, "raw_label": "reference_content", "raw_order": 63, "bbox": [610, 1388, 1097, 1424], "text": "[170] M. Tang, W. Chen, M. D. Weir, W. Thein-Han, H. H. K. Xu, Acta Biomater. 2012, 8, 3436.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [170] M. Tang, W. Chen, M. D. Weir, W. Thein-Han, H. H. K. X"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [170] M. Tang, W. Chen, M. D. Weir, W. Thein-Han, H. H. K. X"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 65, "page": 25, "raw_label": "reference_content", "text": "[170] M. Tang, W. Chen, M. D. Weir, W. Thein-Han, H. H. K. Xu, Acta Biomater. 2012, 8, 3436.", "bbox": [610, 1388, 1097, 1424], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[170]", "number": 170, "kind": "reference", "normalized_text": "[170] M. Tang, W. Chen, M. D. Weir, W. Thein-Han, H. H. K. Xu, Acta Biomater. 2012, 8, 3436."}, "layout_signature": {"width": 487, "width_bucket": 475, "height": 36, "left": 610, "top": 1388, "right": 1097, "bottom": 1424, "x_center": 853.5, "x_center_bucket": 850, "y_center": 1406.0, "x_ratio": 0.7166, "y_ratio": 0.8984, "width_ratio": 0.4089, "height_ratio": 0.023, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 9}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_127", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 25, "block_id": 66, "raw_label": "footer", "raw_order": null, "bbox": [99, 1488, 288, 1504], "text": "Small Methods 2024, 8, 2301283", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["footer label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["footer label"], "span_metadata": [{"size": 6.973800182342529, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 66, "page": 25, "raw_label": "footer", "text": "Small Methods 2024, 8, 2301283", "bbox": [99, 1488, 288, 1504], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "Small Methods 2024, 8, 2301283"}, "layout_signature": {"width": 189, "width_bucket": 200, "height": 16, "left": 99, "top": 1488, "right": 288, "bottom": 1504, "x_center": 193.5, "x_center_bucket": 200, "y_center": 1496.0, "x_ratio": 0.1625, "y_ratio": 0.9559, "width_ratio": 0.1587, "height_ratio": 0.0102, "line_count": 1}, "span_signature": {"font_size": 6.97, "font_size_median": 6.97, "font_size_bucket": 7.0, "font_family_norm": "ScalaSansPro-Italic", "bold": true, "italic": true, "span_count": 5}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_125", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 25, "block_id": 67, "raw_label": "footer", "raw_order": null, "bbox": [527, 1485, 668, 1507], "text": "2301283 (25 of 27)", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.9, "evidence": ["footer label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["footer label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaSansPro-Bold", "flags": 20, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 67, "page": 25, "raw_label": "footer", "text": "2301283 (25 of 27)", "bbox": [527, 1485, 668, 1507], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_dot", "raw_marker": "2301283", "number": 2301283, "kind": "reference", "normalized_text": "2301283 (25 of 27)"}, "layout_signature": {"width": 141, "width_bucket": 150, "height": 22, "left": 527, "top": 1485, "right": 668, "bottom": 1507, "x_center": 597.5, "x_center_bucket": 600, "y_center": 1496.0, "x_ratio": 0.5017, "y_ratio": 0.9559, "width_ratio": 0.1184, "height_ratio": 0.0141, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaSansPro-Bold", "bold": true, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_family_anchor", "reading_band_id": "band_126", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "hard", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 25, "block_id": 68, "raw_label": "footer", "raw_order": null, "bbox": [938, 1487, 1095, 1505], "text": "© 2024 Wiley-VCH GmbH", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["footer label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["footer label"], "span_metadata": [{"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 68, "page": 25, "raw_label": "footer", "text": "© 2024 Wiley-VCH GmbH", "bbox": [938, 1487, 1095, 1505], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "© 2024 Wiley-VCH GmbH"}, "layout_signature": {"width": 157, "width_bucket": 150, "height": 18, "left": 938, "top": 1487, "right": 1095, "bottom": 1505, "x_center": 1016.5, "x_center_bucket": 1025, "y_center": 1496.0, "x_ratio": 0.8535, "y_ratio": 0.9559, "width_ratio": 0.1318, "height_ratio": 0.0115, "line_count": 1}, "span_signature": {"font_size": 6.97, "font_size_median": 6.97, "font_size_bucket": 7.0, "font_family_norm": "ScalaSansPro-Regular", "bold": false, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_128", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 25, "block_id": 69, "raw_label": "aside_text", "raw_order": null, "bbox": [1155, 33, 1171, 1536], "text": "2369608, 2024, 8, Downloaded from https://onlinelibrary.wiley.com/doi/10.1002/smd.202301283 by Shandong University Library, Wiley Online Library on [18/02/2026]. See the Terms and Conditions (https://onlinelibrary.wiley.com/terms-and-conditions) on Wiley Online Library for rules of use; OA articles are governed by the applicable Creative Commons License.", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.95, "evidence": ["margin-band narrow/tall geometry; treated as noise"], "seed_role": "noise", "seed_confidence": 0.95, "seed_evidence": ["margin-band narrow/tall geometry; treated as noise"], "span_metadata": [{"size": 5.03000020980835, "font": "Times-Roman", "flags": 4, "color": 0, "dir": [0.0, 1.0], "wmode": 0}], "raw_observation": {"block_id": 69, "page": 25, "raw_label": "aside_text", "text": "2369608, 2024, 8, Downloaded from https://onlinelibrary.wiley.com/doi/10.1002/smd.202301283 by Shandong University Library, Wiley Online Library on [18/02/2026]. See the Terms and Conditions (https://onlinelibrary.wiley.com/terms-and-conditions) on Wiley Online Library for rules of use; OA articles are governed by the applicable Creative Commons License.", "bbox": [1155, 33, 1171, 1536], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "2369608, 2024, 8, Downloaded from https://onlinelibrary.wiley.com/doi/10.1002/smd.202301283 by Shandong University Library, Wiley Online Library on [18/02/2026]. See the Terms and Conditions (https://onlinelibrary.wiley.com/terms-and-conditions) on Wiley Online Library for rules of use; OA articles are governed by the applicable Creative Commons License."}, "layout_signature": {"width": 16, "width_bucket": 25, "height": 1503, "left": 1155, "top": 33, "right": 1171, "bottom": 1536, "x_center": 1163.0, "x_center_bucket": 1175, "y_center": 784.5, "x_ratio": 0.9765, "y_ratio": 0.5013, "width_ratio": 0.0134, "height_ratio": 0.9604, "line_count": 1}, "span_signature": {"font_size": 5.03, "font_size_median": 5.03, "font_size_bucket": 5.0, "font_family_norm": "Times-Roman", "bold": false, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_128", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 26, "block_id": 0, "raw_label": "header", "raw_order": null, "bbox": [92, 46, 317, 114], "text": "ADVANCED\nSCIENCE NEWS\nwww.advancedsciencenews.co", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["header label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["header label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaSansPro-Bold", "flags": 20, "color": 255, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 0, "page": 26, "raw_label": "header", "text": "ADVANCED\nSCIENCE NEWS\nwww.advancedsciencenews.co", "bbox": [92, 46, 317, 114], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "ADVANCED\nSCIENCE NEWS\nwww.advancedsciencenews.co"}, "layout_signature": {"width": 225, "width_bucket": 225, "height": 68, "left": 92, "top": 46, "right": 317, "bottom": 114, "x_center": 204.5, "x_center_bucket": 200, "y_center": 80.0, "x_ratio": 0.1717, "y_ratio": 0.0511, "width_ratio": 0.1889, "height_ratio": 0.0435, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaSansPro-Bold", "bold": true, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 26, "block_id": 1, "raw_label": "header_image", "raw_order": null, "bbox": [998, 36, 1089, 96], "text": "", "page_width": 1191, "page_height": 1565, "role": "unknown_structural", "role_confidence": 0.2, "evidence": ["unrecognized label 'header_image'"], "seed_role": "unknown_structural", "seed_confidence": 0.2, "seed_evidence": ["unrecognized label 'header_image'"], "span_metadata": null, "raw_observation": {"block_id": 1, "page": 26, "raw_label": "header_image", "text": "", "bbox": [998, 36, 1089, 96], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "empty", "raw_marker": null, "number": null, "kind": null, "normalized_text": ""}, "layout_signature": {"width": 91, "width_bucket": 100, "height": 60, "left": 998, "top": 36, "right": 1089, "bottom": 96, "x_center": 1043.5, "x_center_bucket": 1050, "y_center": 66.0, "x_ratio": 0.8762, "y_ratio": 0.0422, "width_ratio": 0.0764, "height_ratio": 0.0383, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": true, "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_142", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["non-structural role accepted"]}
+{"paper_id": "2HEUD5P9", "page": 26, "block_id": 2, "raw_label": "header", "raw_order": null, "bbox": [897, 99, 1089, 115], "text": "www.small-methods.com", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["header label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["header label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaSansPro-Bold", "flags": 20, "color": 255, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 2, "page": 26, "raw_label": "header", "text": "www.small-methods.com", "bbox": [897, 99, 1089, 115], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "www.small-methods.com"}, "layout_signature": {"width": 192, "width_bucket": 200, "height": 16, "left": 897, "top": 99, "right": 1089, "bottom": 115, "x_center": 993.0, "x_center_bucket": 1000, "y_center": 107.0, "x_ratio": 0.8338, "y_ratio": 0.0684, "width_ratio": 0.1612, "height_ratio": 0.0102, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaSansPro-Bold", "bold": true, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_142", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 26, "block_id": 3, "raw_label": "reference_content", "raw_order": 1, "bbox": [93, 151, 578, 189], "text": "[171] K. Rutledge, Q. Cheng, M. Pryzhkova, G. M. Harris, E. Jabbarzadeh, Tissue Eng. Part C, Methods 2014, 20, 865.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [171] K. Rutledge, Q. Cheng, M. Pryzhkova, G. M. Harris, E. "], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [171] K. Rutledge, Q. Cheng, M. Pryzhkova, G. M. Harris, E. "], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 3, "page": 26, "raw_label": "reference_content", "text": "[171] K. Rutledge, Q. Cheng, M. Pryzhkova, G. M. Harris, E. Jabbarzadeh, Tissue Eng. Part C, Methods 2014, 20, 865.", "bbox": [93, 151, 578, 189], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[171]", "number": 171, "kind": "reference", "normalized_text": "[171] K. Rutledge, Q. Cheng, M. Pryzhkova, G. M. Harris, E. Jabbarzadeh, Tissue Eng. Part C, Methods 2014, 20, 865."}, "layout_signature": {"width": 485, "width_bucket": 475, "height": 38, "left": 93, "top": 151, "right": 578, "bottom": 189, "x_center": 335.5, "x_center_bucket": 325, "y_center": 170.0, "x_ratio": 0.2817, "y_ratio": 0.1086, "width_ratio": 0.4072, "height_ratio": 0.0243, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 8}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_139", "display_cluster_candidate_id": "disp_27_0", "layout_region": "display_zone", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 26, "block_id": 4, "raw_label": "reference_content", "raw_order": 2, "bbox": [95, 191, 579, 268], "text": "[172] F. D'angelo, I. Armentano, I. Cacciotti, R. Tiribuzi, M. Quattrocelli, C. Del Gaudio, E. Fortunati, E. Saino, A. Caraffa, G. G. Cerulli, L. Visai, J. M. Kenny, M. Sampaolesi, A. Bianco, S. Martino, A. Orlacchio, Biomacromolecules 2012, 13, 1350.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [172] F. D'angelo, I. Armentano, I. Cacciotti, R. Tiribuzi, "], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [172] F. D'angelo, I. Armentano, I. Cacciotti, R. Tiribuzi, "], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 4, "page": 26, "raw_label": "reference_content", "text": "[172] F. D'angelo, I. Armentano, I. Cacciotti, R. Tiribuzi, M. Quattrocelli, C. Del Gaudio, E. Fortunati, E. Saino, A. Caraffa, G. G. Cerulli, L. Visai, J. M. Kenny, M. Sampaolesi, A. Bianco, S. Martino, A. Orlacchio, Biomacromolecules 2012, 13, 1350.", "bbox": [95, 191, 579, 268], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[172]", "number": 172, "kind": "reference", "normalized_text": "[172] F. D'angelo, I. Armentano, I. Cacciotti, R. Tiribuzi, M. Quattrocelli, C. Del Gaudio, E. Fortunati, E. Saino, A. Caraffa, G. G. Cerulli, L. Visai, J. M. Kenny, M. Sampaolesi, A. Bianco, S. Martino, A. Orlacchio, Biomacromolecules 2012, 13, 1350."}, "layout_signature": {"width": 484, "width_bucket": 475, "height": 77, "left": 95, "top": 191, "right": 579, "bottom": 268, "x_center": 337.0, "x_center_bucket": 325, "y_center": 229.5, "x_ratio": 0.283, "y_ratio": 0.1466, "width_ratio": 0.4064, "height_ratio": 0.0492, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 30}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_140", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 26, "block_id": 5, "raw_label": "reference_content", "raw_order": 3, "bbox": [95, 271, 579, 328], "text": "[173] M. M. Hasani-Sadrabadi, P. Sarrion, S. Pouraghaei, Y. Chau, S. Ansari, S. Li, T. Aghaloo, A. Moshaverinia, Sci. Transl. Med. 2020, 12, eaay6853.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [173] M. M. Hasani-Sadrabadi, P. Sarrion, S. Pouraghaei, Y. "], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [173] M. M. Hasani-Sadrabadi, P. Sarrion, S. Pouraghaei, Y. "], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 5, "page": 26, "raw_label": "reference_content", "text": "[173] M. M. Hasani-Sadrabadi, P. Sarrion, S. Pouraghaei, Y. Chau, S. Ansari, S. Li, T. Aghaloo, A. Moshaverinia, Sci. Transl. Med. 2020, 12, eaay6853.", "bbox": [95, 271, 579, 328], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[173]", "number": 173, "kind": "reference", "normalized_text": "[173] M. M. Hasani-Sadrabadi, P. Sarrion, S. Pouraghaei, Y. Chau, S. Ansari, S. Li, T. Aghaloo, A. Moshaverinia, Sci. Transl. Med. 2020, 12, eaay6853."}, "layout_signature": {"width": 484, "width_bucket": 475, "height": 57, "left": 95, "top": 271, "right": 579, "bottom": 328, "x_center": 337.0, "x_center_bucket": 325, "y_center": 299.5, "x_ratio": 0.283, "y_ratio": 0.1914, "width_ratio": 0.4064, "height_ratio": 0.0364, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 45}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_139", "display_cluster_candidate_id": "disp_27_0", "layout_region": "display_zone", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 26, "block_id": 6, "raw_label": "reference_content", "raw_order": 4, "bbox": [95, 332, 578, 389], "text": "[174] T. Masaoka, T. Yoshii, M. Yuasa, T. Yamada, T. Taniyama, I. Torigoe, K. Shinomiya, A. Okawa, S. Morita, S. Sotome, Open Biomed. Eng. J. 2016, 10, 2.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [174] T. Masaoka, T. Yoshii, M. Yuasa, T. Yamada, T. Taniyam"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [174] T. Masaoka, T. Yoshii, M. Yuasa, T. Yamada, T. Taniyam"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 6, "page": 26, "raw_label": "reference_content", "text": "[174] T. Masaoka, T. Yoshii, M. Yuasa, T. Yamada, T. Taniyama, I. Torigoe, K. Shinomiya, A. Okawa, S. Morita, S. Sotome, Open Biomed. Eng. J. 2016, 10, 2.", "bbox": [95, 332, 578, 389], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[174]", "number": 174, "kind": "reference", "normalized_text": "[174] T. Masaoka, T. Yoshii, M. Yuasa, T. Yamada, T. Taniyama, I. Torigoe, K. Shinomiya, A. Okawa, S. Morita, S. Sotome, Open Biomed. Eng. J. 2016, 10, 2."}, "layout_signature": {"width": 483, "width_bucket": 475, "height": 57, "left": 95, "top": 332, "right": 578, "bottom": 389, "x_center": 336.5, "x_center_bucket": 325, "y_center": 360.5, "x_ratio": 0.2825, "y_ratio": 0.2304, "width_ratio": 0.4055, "height_ratio": 0.0364, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 10}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_140", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 26, "block_id": 7, "raw_label": "reference_content", "raw_order": 5, "bbox": [94, 391, 578, 410], "text": "[175] Y. He, Y. Dong, X. Chen, R. Lin, Chin. Med. J. (Engl.) 2014, 127, 322.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [175] Y. He, Y. Dong, X. Chen, R. Lin, Chin. Med. J. (Engl.)"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [175] Y. He, Y. Dong, X. Chen, R. Lin, Chin. Med. J. (Engl.)"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 7, "page": 26, "raw_label": "reference_content", "text": "[175] Y. He, Y. Dong, X. Chen, R. Lin, Chin. Med. J. (Engl.) 2014, 127, 322.", "bbox": [94, 391, 578, 410], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[175]", "number": 175, "kind": "reference", "normalized_text": "[175] Y. He, Y. Dong, X. Chen, R. Lin, Chin. Med. J. (Engl.) 2014, 127, 322."}, "layout_signature": {"width": 484, "width_bucket": 475, "height": 19, "left": 94, "top": 391, "right": 578, "bottom": 410, "x_center": 336.0, "x_center_bucket": 325, "y_center": 400.5, "x_ratio": 0.2821, "y_ratio": 0.2559, "width_ratio": 0.4064, "height_ratio": 0.0121, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 8}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_139", "display_cluster_candidate_id": "disp_27_0", "layout_region": "display_zone", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 26, "block_id": 8, "raw_label": "reference_content", "raw_order": 6, "bbox": [95, 413, 578, 469], "text": "[176] L. M. S. Castro-Raucci, M. S. Francischini, L. N. Teixeira, E. P. Ferraz, H. B. Lopes, P. T. De Oliveira, M. Q. Hassan, A. L. Rosa, M. M. Beloti, J. Cell. Biochem. 2016, 117, 1718.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [176] L. M. S. Castro-Raucci, M. S. Francischini, L. N. Teix"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [176] L. M. S. Castro-Raucci, M. S. Francischini, L. N. Teix"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 8, "page": 26, "raw_label": "reference_content", "text": "[176] L. M. S. Castro-Raucci, M. S. Francischini, L. N. Teixeira, E. P. Ferraz, H. B. Lopes, P. T. De Oliveira, M. Q. Hassan, A. L. Rosa, M. M. Beloti, J. Cell. Biochem. 2016, 117, 1718.", "bbox": [95, 413, 578, 469], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[176]", "number": 176, "kind": "reference", "normalized_text": "[176] L. M. S. Castro-Raucci, M. S. Francischini, L. N. Teixeira, E. P. Ferraz, H. B. Lopes, P. T. De Oliveira, M. Q. Hassan, A. L. Rosa, M. M. Beloti, J. Cell. Biochem. 2016, 117, 1718."}, "layout_signature": {"width": 483, "width_bucket": 475, "height": 56, "left": 95, "top": 413, "right": 578, "bottom": 469, "x_center": 336.5, "x_center_bucket": 325, "y_center": 441.0, "x_ratio": 0.2825, "y_ratio": 0.2818, "width_ratio": 0.4055, "height_ratio": 0.0358, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 9}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_140", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 26, "block_id": 9, "raw_label": "reference_content", "raw_order": 7, "bbox": [94, 470, 578, 508], "text": "[177] L. Cheng, Z. Chen, Z. Cai, J. Zhao, M. Lu, J. Liang, F. Wang, J. Qi, W. Cui, L. Deng, Small 2020, 16, 2005433.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [177] L. Cheng, Z. Chen, Z. Cai, J. Zhao, M. Lu, J. Liang, F"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [177] L. Cheng, Z. Chen, Z. Cai, J. Zhao, M. Lu, J. Liang, F"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 9, "page": 26, "raw_label": "reference_content", "text": "[177] L. Cheng, Z. Chen, Z. Cai, J. Zhao, M. Lu, J. Liang, F. Wang, J. Qi, W. Cui, L. Deng, Small 2020, 16, 2005433.", "bbox": [94, 470, 578, 508], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[177]", "number": 177, "kind": "reference", "normalized_text": "[177] L. Cheng, Z. Chen, Z. Cai, J. Zhao, M. Lu, J. Liang, F. Wang, J. Qi, W. Cui, L. Deng, Small 2020, 16, 2005433."}, "layout_signature": {"width": 484, "width_bucket": 475, "height": 38, "left": 94, "top": 470, "right": 578, "bottom": 508, "x_center": 336.0, "x_center_bucket": 325, "y_center": 489.0, "x_ratio": 0.2821, "y_ratio": 0.3125, "width_ratio": 0.4064, "height_ratio": 0.0243, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 9}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_138", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 26, "block_id": 10, "raw_label": "reference_content", "raw_order": 8, "bbox": [95, 510, 578, 547], "text": "[178] R. Xue, Y. Qian, L. Li, G. Yao, Li Yang, Y. Sun, Stem Cell. Res. Ther. 2017, 8, 148.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [178] R. Xue, Y. Qian, L. Li, G. Yao, Li Yang, Y. Sun, Stem "], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [178] R. Xue, Y. Qian, L. Li, G. Yao, Li Yang, Y. Sun, Stem "], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 10, "page": 26, "raw_label": "reference_content", "text": "[178] R. Xue, Y. Qian, L. Li, G. Yao, Li Yang, Y. Sun, Stem Cell. Res. Ther. 2017, 8, 148.", "bbox": [95, 510, 578, 547], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[178]", "number": 178, "kind": "reference", "normalized_text": "[178] R. Xue, Y. Qian, L. Li, G. Yao, Li Yang, Y. Sun, Stem Cell. Res. Ther. 2017, 8, 148."}, "layout_signature": {"width": 483, "width_bucket": 475, "height": 37, "left": 95, "top": 510, "right": 578, "bottom": 547, "x_center": 336.5, "x_center_bucket": 325, "y_center": 528.5, "x_ratio": 0.2825, "y_ratio": 0.3377, "width_ratio": 0.4055, "height_ratio": 0.0236, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 37}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_141", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "hard", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 26, "block_id": 11, "raw_label": "reference_content", "raw_order": 9, "bbox": [605, 151, 1088, 189], "text": "[179] S. Midha, S. Chameettachal, E. Dey, S. Ghosh, ACS Biomater. Sci. Eng. 2017, 3, 1062.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [179] S. Midha, S. Chameettachal, E. Dey, S. Ghosh, ACS Biom"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [179] S. Midha, S. Chameettachal, E. Dey, S. Ghosh, ACS Biom"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 11, "page": 26, "raw_label": "reference_content", "text": "[179] S. Midha, S. Chameettachal, E. Dey, S. Ghosh, ACS Biomater. Sci. Eng. 2017, 3, 1062.", "bbox": [605, 151, 1088, 189], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[179]", "number": 179, "kind": "reference", "normalized_text": "[179] S. Midha, S. Chameettachal, E. Dey, S. Ghosh, ACS Biomater. Sci. Eng. 2017, 3, 1062."}, "layout_signature": {"width": 483, "width_bucket": 475, "height": 38, "left": 605, "top": 151, "right": 1088, "bottom": 189, "x_center": 846.5, "x_center_bucket": 850, "y_center": 170.0, "x_ratio": 0.7107, "y_ratio": 0.1086, "width_ratio": 0.4055, "height_ratio": 0.0243, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 28}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_142", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 26, "block_id": 12, "raw_label": "reference_content", "raw_order": 10, "bbox": [606, 191, 1089, 230], "text": "[180] S. Y. Choi, M. S. Song, P. D. Ryu, A. T. Lam, S. W. Joo, S. Y. Lee, Int. J. Nanomed. 2015, 10, 4383.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [180] S. Y. Choi, M. S. Song, P. D. Ryu, A. T. Lam, S. W. Jo"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [180] S. Y. Choi, M. S. Song, P. D. Ryu, A. T. Lam, S. W. Jo"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 12, "page": 26, "raw_label": "reference_content", "text": "[180] S. Y. Choi, M. S. Song, P. D. Ryu, A. T. Lam, S. W. Joo, S. Y. Lee, Int. J. Nanomed. 2015, 10, 4383.", "bbox": [606, 191, 1089, 230], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[180]", "number": 180, "kind": "reference", "normalized_text": "[180] S. Y. Choi, M. S. Song, P. D. Ryu, A. T. Lam, S. W. Joo, S. Y. Lee, Int. J. Nanomed. 2015, 10, 4383."}, "layout_signature": {"width": 483, "width_bucket": 475, "height": 39, "left": 606, "top": 191, "right": 1089, "bottom": 230, "x_center": 847.5, "x_center_bucket": 850, "y_center": 210.5, "x_ratio": 0.7116, "y_ratio": 0.1345, "width_ratio": 0.4055, "height_ratio": 0.0249, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 9}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_142", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 26, "block_id": 13, "raw_label": "reference_content", "raw_order": 11, "bbox": [606, 231, 1088, 269], "text": "[181] V. Deregowski, E. Gazzerro, L. Priest, S. Rydziel, E. Canalis, J. Biol. Chem. 2006, 281, 6203.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [181] V. Deregowski, E. Gazzerro, L. Priest, S. Rydziel, E. "], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [181] V. Deregowski, E. Gazzerro, L. Priest, S. Rydziel, E. "], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 13, "page": 26, "raw_label": "reference_content", "text": "[181] V. Deregowski, E. Gazzerro, L. Priest, S. Rydziel, E. Canalis, J. Biol. Chem. 2006, 281, 6203.", "bbox": [606, 231, 1088, 269], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[181]", "number": 181, "kind": "reference", "normalized_text": "[181] V. Deregowski, E. Gazzerro, L. Priest, S. Rydziel, E. Canalis, J. Biol. Chem. 2006, 281, 6203."}, "layout_signature": {"width": 482, "width_bucket": 475, "height": 38, "left": 606, "top": 231, "right": 1088, "bottom": 269, "x_center": 847.0, "x_center_bucket": 850, "y_center": 250.0, "x_ratio": 0.7112, "y_ratio": 0.1597, "width_ratio": 0.4047, "height_ratio": 0.0243, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 9}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_136", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 26, "block_id": 14, "raw_label": "reference_content", "raw_order": 12, "bbox": [606, 272, 1089, 327], "text": "[182] So-Ra Jung, No-J Song, D. K. Yang, Y.-J. Cho, B.-J. Kim, J.-W. Hong, Ui J Yun, D.-G. Jo, Y. M. Lee, S. Y. Choi, K. W. Park, Nutr. Res. 2013, 33, 162.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [182] So-Ra Jung, No-J Song, D. K. Yang, Y.-J. Cho, B.-J. Ki"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [182] So-Ra Jung, No-J Song, D. K. Yang, Y.-J. Cho, B.-J. Ki"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 14, "page": 26, "raw_label": "reference_content", "text": "[182] So-Ra Jung, No-J Song, D. K. Yang, Y.-J. Cho, B.-J. Kim, J.-W. Hong, Ui J Yun, D.-G. Jo, Y. M. Lee, S. Y. Choi, K. W. Park, Nutr. Res. 2013, 33, 162.", "bbox": [606, 272, 1089, 327], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[182]", "number": 182, "kind": "reference", "normalized_text": "[182] So-Ra Jung, No-J Song, D. K. Yang, Y.-J. Cho, B.-J. Kim, J.-W. Hong, Ui J Yun, D.-G. Jo, Y. M. Lee, S. Y. Choi, K. W. Park, Nutr. Res. 2013, 33, 162."}, "layout_signature": {"width": 483, "width_bucket": 475, "height": 55, "left": 606, "top": 272, "right": 1089, "bottom": 327, "x_center": 847.5, "x_center_bucket": 850, "y_center": 299.5, "x_ratio": 0.7116, "y_ratio": 0.1914, "width_ratio": 0.4055, "height_ratio": 0.0351, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 9}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_136", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 26, "block_id": 15, "raw_label": "reference_content", "raw_order": 13, "bbox": [606, 331, 1089, 369], "text": "[183] X. Guo, H. Jiang, X. Zong, Le Du, J. Zhao, D. Zhang, G. Song, X. Jin, J. Biomed. Mater. Res., Part A 2020, 108, 1035.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [183] X. Guo, H. Jiang, X. Zong, Le Du, J. Zhao, D. Zhang, G"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [183] X. Guo, H. Jiang, X. Zong, Le Du, J. Zhao, D. Zhang, G"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 15, "page": 26, "raw_label": "reference_content", "text": "[183] X. Guo, H. Jiang, X. Zong, Le Du, J. Zhao, D. Zhang, G. Song, X. Jin, J. Biomed. Mater. Res., Part A 2020, 108, 1035.", "bbox": [606, 331, 1089, 369], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[183]", "number": 183, "kind": "reference", "normalized_text": "[183] X. Guo, H. Jiang, X. Zong, Le Du, J. Zhao, D. Zhang, G. Song, X. Jin, J. Biomed. Mater. Res., Part A 2020, 108, 1035."}, "layout_signature": {"width": 483, "width_bucket": 475, "height": 38, "left": 606, "top": 331, "right": 1089, "bottom": 369, "x_center": 847.5, "x_center_bucket": 850, "y_center": 350.0, "x_ratio": 0.7116, "y_ratio": 0.2236, "width_ratio": 0.4055, "height_ratio": 0.0243, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 8}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_136", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 26, "block_id": 16, "raw_label": "reference_content", "raw_order": 14, "bbox": [606, 370, 1090, 409], "text": "[184] L. Xia, Z. Yin, L. Mao, X. Wang, J. Liu, X. Jiang, Z. Zhang, K. Lin, J. Chang, B. Fang, Sci. Rep. 2016, 6, 22005.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [184] L. Xia, Z. Yin, L. Mao, X. Wang, J. Liu, X. Jiang, Z. "], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [184] L. Xia, Z. Yin, L. Mao, X. Wang, J. Liu, X. Jiang, Z. "], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 16, "page": 26, "raw_label": "reference_content", "text": "[184] L. Xia, Z. Yin, L. Mao, X. Wang, J. Liu, X. Jiang, Z. Zhang, K. Lin, J. Chang, B. Fang, Sci. Rep. 2016, 6, 22005.", "bbox": [606, 370, 1090, 409], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[184]", "number": 184, "kind": "reference", "normalized_text": "[184] L. Xia, Z. Yin, L. Mao, X. Wang, J. Liu, X. Jiang, Z. Zhang, K. Lin, J. Chang, B. Fang, Sci. Rep. 2016, 6, 22005."}, "layout_signature": {"width": 484, "width_bucket": 475, "height": 39, "left": 606, "top": 370, "right": 1090, "bottom": 409, "x_center": 848.0, "x_center_bucket": 850, "y_center": 389.5, "x_ratio": 0.712, "y_ratio": 0.2489, "width_ratio": 0.4064, "height_ratio": 0.0249, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 9}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_136", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 26, "block_id": 17, "raw_label": "reference_content", "raw_order": 15, "bbox": [606, 411, 1089, 446], "text": "[185] W. Gong, Y. Dong, S. Wang, X. Gao, X. Chen, RSC Adv. 2017, 7, 13760.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [185] W. Gong, Y. Dong, S. Wang, X. Gao, X. Chen, RSC Adv. 2"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [185] W. Gong, Y. Dong, S. Wang, X. Gao, X. Chen, RSC Adv. 2"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 17, "page": 26, "raw_label": "reference_content", "text": "[185] W. Gong, Y. Dong, S. Wang, X. Gao, X. Chen, RSC Adv. 2017, 7, 13760.", "bbox": [606, 411, 1089, 446], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[185]", "number": 185, "kind": "reference", "normalized_text": "[185] W. Gong, Y. Dong, S. Wang, X. Gao, X. Chen, RSC Adv. 2017, 7, 13760."}, "layout_signature": {"width": 483, "width_bucket": 475, "height": 35, "left": 606, "top": 411, "right": 1089, "bottom": 446, "x_center": 847.5, "x_center_bucket": 850, "y_center": 428.5, "x_ratio": 0.7116, "y_ratio": 0.2738, "width_ratio": 0.4055, "height_ratio": 0.0224, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 32}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_136", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 26, "block_id": 18, "raw_label": "reference_content", "raw_order": 16, "bbox": [606, 450, 1088, 487], "text": "[186] M. Li, X. Chu, D. Wang, L. Jian, L. Liu, M. Yao, D. Zhang, Y. Zheng, X. Liu, Yu Zhang, F. Peng, Biomaterials 2022, 282, 121408.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [186] M. Li, X. Chu, D. Wang, L. Jian, L. Liu, M. Yao, D. Zh"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [186] M. Li, X. Chu, D. Wang, L. Jian, L. Liu, M. Yao, D. Zh"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 18, "page": 26, "raw_label": "reference_content", "text": "[186] M. Li, X. Chu, D. Wang, L. Jian, L. Liu, M. Yao, D. Zhang, Y. Zheng, X. Liu, Yu Zhang, F. Peng, Biomaterials 2022, 282, 121408.", "bbox": [606, 450, 1088, 487], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[186]", "number": 186, "kind": "reference", "normalized_text": "[186] M. Li, X. Chu, D. Wang, L. Jian, L. Liu, M. Yao, D. Zhang, Y. Zheng, X. Liu, Yu Zhang, F. Peng, Biomaterials 2022, 282, 121408."}, "layout_signature": {"width": 482, "width_bucket": 475, "height": 37, "left": 606, "top": 450, "right": 1088, "bottom": 487, "x_center": 847.0, "x_center_bucket": 850, "y_center": 468.5, "x_ratio": 0.7112, "y_ratio": 0.2994, "width_ratio": 0.4047, "height_ratio": 0.0236, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 9}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_136", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 26, "block_id": 19, "raw_label": "reference_content", "raw_order": 17, "bbox": [605, 490, 1036, 509], "text": "[187] C. Wang, K. Lin, J. Chang, J. Sun, Biomaterials 2013, 34, 64.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [187] C. Wang, K. Lin, J. Chang, J. Sun, Biomaterials 2013, "], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [187] C. Wang, K. Lin, J. Chang, J. Sun, Biomaterials 2013, "], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 19, "page": 26, "raw_label": "reference_content", "text": "[187] C. Wang, K. Lin, J. Chang, J. Sun, Biomaterials 2013, 34, 64.", "bbox": [605, 490, 1036, 509], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[187]", "number": 187, "kind": "reference", "normalized_text": "[187] C. Wang, K. Lin, J. Chang, J. Sun, Biomaterials 2013, 34, 64."}, "layout_signature": {"width": 431, "width_bucket": 425, "height": 19, "left": 605, "top": 490, "right": 1036, "bottom": 509, "x_center": 820.5, "x_center_bucket": 825, "y_center": 499.5, "x_ratio": 0.6889, "y_ratio": 0.3192, "width_ratio": 0.3619, "height_ratio": 0.0121, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 8}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_136", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 26, "block_id": 20, "raw_label": "reference_content", "raw_order": 18, "bbox": [606, 511, 1088, 548], "text": "[188] C. Liu, Q. Yu, Z. Yuan, Q. Guo, X. Liao, F. Han, T. Feng, G. Liu, R. Zhao, Z. Zhu, H. Mao, C. Zhu, B. Li, Bioact. Mater. 2023, 25, 445.", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.85, "evidence": ["reference content label: [188] C. Liu, Q. Yu, Z. Yuan, Q. Guo, X. Liao, F. Han, T. Fe"], "seed_role": "reference_item", "seed_confidence": 0.85, "seed_evidence": ["reference content label: [188] C. Liu, Q. Yu, Z. Yuan, Q. Guo, X. Liao, F. Han, T. Fe"], "span_metadata": [{"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 7.970099925994873, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 20, "page": 26, "raw_label": "reference_content", "text": "[188] C. Liu, Q. Yu, Z. Yuan, Q. Guo, X. Liao, F. Han, T. Feng, G. Liu, R. Zhao, Z. Zhu, H. Mao, C. Zhu, B. Li, Bioact. Mater. 2023, 25, 445.", "bbox": [606, 511, 1088, 548], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_bracket", "raw_marker": "[188]", "number": 188, "kind": "reference", "normalized_text": "[188] C. Liu, Q. Yu, Z. Yuan, Q. Guo, X. Liao, F. Han, T. Feng, G. Liu, R. Zhao, Z. Zhu, H. Mao, C. Zhu, B. Li, Bioact. Mater. 2023, 25, 445."}, "layout_signature": {"width": 482, "width_bucket": 475, "height": 37, "left": 606, "top": 511, "right": 1088, "bottom": 548, "x_center": 847.0, "x_center_bucket": 850, "y_center": 529.5, "x_ratio": 0.7112, "y_ratio": 0.3383, "width_ratio": 0.4047, "height_ratio": 0.0236, "line_count": 1}, "span_signature": {"font_size": 7.97, "font_size_median": 7.97, "font_size_bucket": 8.0, "font_family_norm": "ScalaSansPro-Regular", "bold": true, "italic": true, "span_count": 41}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_marker", "reading_band_id": "band_136", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "weak", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 26, "block_id": 21, "raw_label": "image", "raw_order": null, "bbox": [115, 600, 314, 855], "text": "", "page_width": 1191, "page_height": 1565, "role": "author_bio_asset", "role_confidence": 0.85, "evidence": ["media label: image"], "seed_role": "media_asset", "seed_confidence": 0.85, "seed_evidence": ["media label: image"], "span_metadata": null, "raw_observation": {"block_id": 21, "page": 26, "raw_label": "image", "text": "", "bbox": [115, 600, 314, 855], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "empty", "raw_marker": null, "number": null, "kind": null, "normalized_text": ""}, "layout_signature": {"width": 199, "width_bucket": 200, "height": 255, "left": 115, "top": 600, "right": 314, "bottom": 855, "x_center": 214.5, "x_center_bucket": 225, "y_center": 727.5, "x_ratio": 0.1801, "y_ratio": 0.4649, "width_ratio": 0.1671, "height_ratio": 0.1629, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_133", "display_cluster_candidate_id": "disp_26_0", "layout_region": "display_zone", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"], "asset_family_hint": "figure_like", "asset_family_confidence": 0.7, "asset_family_evidence": ["raw_label:image"], "_object_owner_family": "author_bio", "_excluded_from_figure_inventory": true}
+{"paper_id": "2HEUD5P9", "page": 26, "block_id": 22, "raw_label": "vision_footnote", "raw_order": null, "bbox": [327, 597, 1070, 684], "text": "Yuxin Bai is now a postdoctoral fellow in Professor Rongrong Zhu's group at Tongji University, School of Life Science and Technology. Under the supervision of Professor Rongrong Zhu, he obtained his Ph.D. degree from Tongji University, China, in 2023. Currently, his research interests focus on biomaterials for the regulation of stem cells fate.", "page_width": 1191, "page_height": 1565, "role": "backmatter_body", "role_confidence": 0.7, "evidence": ["vision_footnote label: Yuxin Bai is now a postdoctoral fellow in Professor Rongrong"], "seed_role": "footnote", "seed_confidence": 0.7, "seed_evidence": ["vision_footnote label: Yuxin Bai is now a postdoctoral fellow in Professor Rongrong"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaSansPro-Bold", "flags": 20, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaSansPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaSansPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaSansPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaSansPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 22, "page": 26, "raw_label": "vision_footnote", "text": "Yuxin Bai is now a postdoctoral fellow in Professor Rongrong Zhu's group at Tongji University, School of Life Science and Technology. Under the supervision of Professor Rongrong Zhu, he obtained his Ph.D. degree from Tongji University, China, in 2023. Currently, his research interests focus on biomaterials for the regulation of stem cells fate.", "bbox": [327, 597, 1070, 684], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "Yuxin Bai is now a postdoctoral fellow in Professor Rongrong Zhu's group at Tongji University, School of Life Science and Technology. Under the supervision of Professor Rongrong Zhu, he obtained his Ph.D. degree from Tongji University, China, in 2023. Currently, his research interests focus on biomaterials for the regulation of stem cells fate."}, "layout_signature": {"width": 743, "width_bucket": 750, "height": 87, "left": 327, "top": 597, "right": 1070, "bottom": 684, "x_center": 698.5, "x_center_bucket": 700, "y_center": 640.5, "x_ratio": 0.5865, "y_ratio": 0.4093, "width_ratio": 0.6238, "height_ratio": 0.0556, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaSansPro-Bold", "bold": true, "italic": true, "span_count": 5}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "", "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_134", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.0, "decision": "body", "evidence": []}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"], "_object_owner_family": "author_bio", "_excluded_from_figure_inventory": true}
+{"paper_id": "2HEUD5P9", "page": 26, "block_id": 23, "raw_label": "image", "raw_order": null, "bbox": [114, 890, 314, 1144], "text": "", "page_width": 1191, "page_height": 1565, "role": "author_bio_asset", "role_confidence": 0.85, "evidence": ["media label: image"], "seed_role": "media_asset", "seed_confidence": 0.85, "seed_evidence": ["media label: image"], "span_metadata": null, "raw_observation": {"block_id": 23, "page": 26, "raw_label": "image", "text": "", "bbox": [114, 890, 314, 1144], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "empty", "raw_marker": null, "number": null, "kind": null, "normalized_text": ""}, "layout_signature": {"width": 200, "width_bucket": 200, "height": 254, "left": 114, "top": 890, "right": 314, "bottom": 1144, "x_center": 214.0, "x_center_bucket": 225, "y_center": 1017.0, "x_ratio": 0.1797, "y_ratio": 0.6498, "width_ratio": 0.1679, "height_ratio": 0.1623, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_133", "display_cluster_candidate_id": "disp_26_0", "layout_region": "display_zone", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"], "asset_family_hint": "figure_like", "asset_family_confidence": 0.7, "asset_family_evidence": ["raw_label:image"], "_object_owner_family": "author_bio", "_excluded_from_figure_inventory": true}
+{"paper_id": "2HEUD5P9", "page": 26, "block_id": 24, "raw_label": "vision_footnote", "raw_order": null, "bbox": [326, 887, 1060, 976], "text": "Zhaojie Wang is a postdoctoral fellow in Professor Rongrong Zhu's group at Tongji University, School of Life Science and Technology. She obtained her Ph.D. degree from Tongji University, China, in 2019. Currently, her research interests focus on the application of nanomaterials in tissue regeneration and repair.", "page_width": 1191, "page_height": 1565, "role": "backmatter_body", "role_confidence": 0.7, "evidence": ["vision_footnote label: Zhaojie Wang is a postdoctoral fellow in Professor Rongrong "], "seed_role": "footnote", "seed_confidence": 0.7, "seed_evidence": ["vision_footnote label: Zhaojie Wang is a postdoctoral fellow in Professor Rongrong "], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaSansPro-Bold", "flags": 20, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaSansPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaSansPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaSansPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaSansPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 24, "page": 26, "raw_label": "vision_footnote", "text": "Zhaojie Wang is a postdoctoral fellow in Professor Rongrong Zhu's group at Tongji University, School of Life Science and Technology. She obtained her Ph.D. degree from Tongji University, China, in 2019. Currently, her research interests focus on the application of nanomaterials in tissue regeneration and repair.", "bbox": [326, 887, 1060, 976], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "Zhaojie Wang is a postdoctoral fellow in Professor Rongrong Zhu's group at Tongji University, School of Life Science and Technology. She obtained her Ph.D. degree from Tongji University, China, in 2019. Currently, her research interests focus on the application of nanomaterials in tissue regeneration and repair."}, "layout_signature": {"width": 734, "width_bucket": 725, "height": 89, "left": 326, "top": 887, "right": 1060, "bottom": 976, "x_center": 693.0, "x_center_bucket": 700, "y_center": 931.5, "x_ratio": 0.5819, "y_ratio": 0.5952, "width_ratio": 0.6163, "height_ratio": 0.0569, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaSansPro-Bold", "bold": true, "italic": true, "span_count": 5}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "", "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_134", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.0, "decision": "body", "evidence": []}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"], "_object_owner_family": "author_bio", "_excluded_from_figure_inventory": true}
+{"paper_id": "2HEUD5P9", "page": 26, "block_id": 25, "raw_label": "footer", "raw_order": null, "bbox": [94, 1488, 282, 1504], "text": "Small Methods 2024, 8, 2301283", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["footer label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["footer label"], "span_metadata": [{"size": 6.973800182342529, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 25, "page": 26, "raw_label": "footer", "text": "Small Methods 2024, 8, 2301283", "bbox": [94, 1488, 282, 1504], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "Small Methods 2024, 8, 2301283"}, "layout_signature": {"width": 188, "width_bucket": 200, "height": 16, "left": 94, "top": 1488, "right": 282, "bottom": 1504, "x_center": 188.0, "x_center_bucket": 200, "y_center": 1496.0, "x_ratio": 0.1579, "y_ratio": 0.9559, "width_ratio": 0.1579, "height_ratio": 0.0102, "line_count": 1}, "span_signature": {"font_size": 6.97, "font_size_median": 6.97, "font_size_bucket": 7.0, "font_family_norm": "ScalaSansPro-Italic", "bold": true, "italic": true, "span_count": 5}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_131", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 26, "block_id": 26, "raw_label": "number", "raw_order": null, "bbox": [521, 1485, 662, 1507], "text": "2301283 (26 of 27)", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.9, "evidence": ["page number label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["page number label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaSansPro-Bold", "flags": 20, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 26, "page": 26, "raw_label": "number", "text": "2301283 (26 of 27)", "bbox": [521, 1485, 662, 1507], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_dot", "raw_marker": "2301283", "number": 2301283, "kind": "reference", "normalized_text": "2301283 (26 of 27)"}, "layout_signature": {"width": 141, "width_bucket": 150, "height": 22, "left": 521, "top": 1485, "right": 662, "bottom": 1507, "x_center": 591.5, "x_center_bucket": 600, "y_center": 1496.0, "x_ratio": 0.4966, "y_ratio": 0.9559, "width_ratio": 0.1184, "height_ratio": 0.0141, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaSansPro-Bold", "bold": true, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_family_anchor", "reading_band_id": "band_135", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "hard", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 26, "block_id": 27, "raw_label": "footer", "raw_order": null, "bbox": [932, 1488, 1089, 1505], "text": "© 2024 Wiley-VCH GmbH", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["footer label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["footer label"], "span_metadata": [{"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 27, "page": 26, "raw_label": "footer", "text": "© 2024 Wiley-VCH GmbH", "bbox": [932, 1488, 1089, 1505], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "© 2024 Wiley-VCH GmbH"}, "layout_signature": {"width": 157, "width_bucket": 150, "height": 17, "left": 932, "top": 1488, "right": 1089, "bottom": 1505, "x_center": 1010.5, "x_center_bucket": 1000, "y_center": 1496.5, "x_ratio": 0.8484, "y_ratio": 0.9562, "width_ratio": 0.1318, "height_ratio": 0.0109, "line_count": 1}, "span_signature": {"font_size": 6.97, "font_size_median": 6.97, "font_size_bucket": 7.0, "font_family_norm": "ScalaSansPro-Regular", "bold": false, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_137", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 26, "block_id": 28, "raw_label": "aside_text", "raw_order": null, "bbox": [1155, 33, 1171, 1536], "text": "2369608, 2024, 8, Downloaded from https://onlinelibrary.wiley.com/doi/10.1002/smd.202301283 by Shandong University Library, Wiley Online Library on [18/02/2026]. See the Terms and Conditions (https://onlinelibrary.wiley.com/terms-and-conditions) on Wiley Online Library for rules of use; OA articles are governed by the applicable Creative Commons License.", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.95, "evidence": ["margin-band narrow/tall geometry; treated as noise"], "seed_role": "noise", "seed_confidence": 0.95, "seed_evidence": ["margin-band narrow/tall geometry; treated as noise"], "span_metadata": [{"size": 5.03000020980835, "font": "Times-Roman", "flags": 4, "color": 0, "dir": [0.0, 1.0], "wmode": 0}], "raw_observation": {"block_id": 28, "page": 26, "raw_label": "aside_text", "text": "2369608, 2024, 8, Downloaded from https://onlinelibrary.wiley.com/doi/10.1002/smd.202301283 by Shandong University Library, Wiley Online Library on [18/02/2026]. See the Terms and Conditions (https://onlinelibrary.wiley.com/terms-and-conditions) on Wiley Online Library for rules of use; OA articles are governed by the applicable Creative Commons License.", "bbox": [1155, 33, 1171, 1536], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "2369608, 2024, 8, Downloaded from https://onlinelibrary.wiley.com/doi/10.1002/smd.202301283 by Shandong University Library, Wiley Online Library on [18/02/2026]. See the Terms and Conditions (https://onlinelibrary.wiley.com/terms-and-conditions) on Wiley Online Library for rules of use; OA articles are governed by the applicable Creative Commons License."}, "layout_signature": {"width": 16, "width_bucket": 25, "height": 1503, "left": 1155, "top": 33, "right": 1171, "bottom": 1536, "x_center": 1163.0, "x_center_bucket": 1175, "y_center": 784.5, "x_ratio": 0.9765, "y_ratio": 0.5013, "width_ratio": 0.0134, "height_ratio": 0.9604, "line_count": 1}, "span_signature": {"font_size": 5.03, "font_size_median": 5.03, "font_size_bucket": 5.0, "font_family_norm": "Times-Roman", "bold": false, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_137", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 27, "block_id": 0, "raw_label": "header", "raw_order": null, "bbox": [98, 46, 345, 117], "text": "ADVANCED\nSCIENCE NEWS\nwww.advancedsciencenews.com", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["header label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["header label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaSansPro-Bold", "flags": 20, "color": 255, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 0, "page": 27, "raw_label": "header", "text": "ADVANCED\nSCIENCE NEWS\nwww.advancedsciencenews.com", "bbox": [98, 46, 345, 117], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "ADVANCED\nSCIENCE NEWS\nwww.advancedsciencenews.com"}, "layout_signature": {"width": 247, "width_bucket": 250, "height": 71, "left": 98, "top": 46, "right": 345, "bottom": 117, "x_center": 221.5, "x_center_bucket": 225, "y_center": 81.5, "x_ratio": 0.186, "y_ratio": 0.0521, "width_ratio": 0.2074, "height_ratio": 0.0454, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaSansPro-Bold", "bold": true, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 27, "block_id": 1, "raw_label": "header", "raw_order": null, "bbox": [1001, 35, 1096, 115], "text": "small methods\nmethods.com", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["header label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["header label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaSansPro-Bold", "flags": 20, "color": 255, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 1, "page": 27, "raw_label": "header", "text": "small methods\nmethods.com", "bbox": [1001, 35, 1096, 115], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "small methods\nmethods.com"}, "layout_signature": {"width": 95, "width_bucket": 100, "height": 80, "left": 1001, "top": 35, "right": 1096, "bottom": 115, "x_center": 1048.5, "x_center_bucket": 1050, "y_center": 75.0, "x_ratio": 0.8804, "y_ratio": 0.0479, "width_ratio": 0.0798, "height_ratio": 0.0511, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaSansPro-Bold", "bold": true, "italic": true, "span_count": 1}, "_in_visual_container": true, "_container_bbox": [1005.7522789906125, 37.836628863963085, 1084.0337389451988, 91.04600210547972], "_container_text": "small methods\nmethods.com", "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_142", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.6, "decision": "structured_insert_candidate", "evidence": ["visual_container", "narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 27, "block_id": 2, "raw_label": "header", "raw_order": null, "bbox": [903, 97, 1096, 116], "text": "www.small-methods.com", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["header label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["header label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaSansPro-Bold", "flags": 20, "color": 255, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 2, "page": 27, "raw_label": "header", "text": "www.small-methods.com", "bbox": [903, 97, 1096, 116], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "www.small-methods.com"}, "layout_signature": {"width": 193, "width_bucket": 200, "height": 19, "left": 903, "top": 97, "right": 1096, "bottom": 116, "x_center": 999.5, "x_center_bucket": 1000, "y_center": 106.5, "x_ratio": 0.8392, "y_ratio": 0.0681, "width_ratio": 0.162, "height_ratio": 0.0121, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaSansPro-Bold", "bold": true, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_142", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 27, "block_id": 3, "raw_label": "image", "raw_order": null, "bbox": [120, 172, 320, 428], "text": "", "page_width": 1191, "page_height": 1565, "role": "author_bio_asset", "role_confidence": 0.85, "evidence": ["media label: image"], "seed_role": "media_asset", "seed_confidence": 0.85, "seed_evidence": ["media label: image"], "span_metadata": null, "raw_observation": {"block_id": 3, "page": 27, "raw_label": "image", "text": "", "bbox": [120, 172, 320, 428], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "empty", "raw_marker": null, "number": null, "kind": null, "normalized_text": ""}, "layout_signature": {"width": 200, "width_bucket": 200, "height": 256, "left": 120, "top": 172, "right": 320, "bottom": 428, "x_center": 220.0, "x_center_bucket": 225, "y_center": 300.0, "x_ratio": 0.1847, "y_ratio": 0.1917, "width_ratio": 0.1679, "height_ratio": 0.1636, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_139", "display_cluster_candidate_id": "disp_27_0", "layout_region": "display_zone", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"], "asset_family_hint": "figure_like", "asset_family_confidence": 0.7, "asset_family_evidence": ["raw_label:image"], "_object_owner_family": "author_bio", "_excluded_from_figure_inventory": true}
+{"paper_id": "2HEUD5P9", "page": 27, "block_id": 4, "raw_label": "text", "raw_order": 1, "bbox": [333, 168, 1064, 282], "text": "Shengguang Chen is a clinical doctor at Gongli Hospital of Shanghai Pudong New Area. He has been engaged in clinical research on endocrine and metabolic diseases. He received his Ph.D. degree in medical from Tongji University. Currently, his research interests mainly focus on the diagnosis and treatment of metabolic diseases, especially bone metabolic diseases, including osteoporosis, hyperparathyroidism, osteomalacia, osteogenesis imperfecta, osteoarthritis, etc.", "page_width": 1191, "page_height": 1565, "role": "body_paragraph", "role_confidence": 0.6, "evidence": ["default body_paragraph for text label"], "seed_role": "body_paragraph", "seed_confidence": 0.6, "seed_evidence": ["default body_paragraph for text label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaSansPro-Bold", "flags": 20, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaSansPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaSansPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaSansPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaSansPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaSansPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 4, "page": 27, "raw_label": "text", "text": "Shengguang Chen is a clinical doctor at Gongli Hospital of Shanghai Pudong New Area. He has been engaged in clinical research on endocrine and metabolic diseases. He received his Ph.D. degree in medical from Tongji University. Currently, his research interests mainly focus on the diagnosis and treatment of metabolic diseases, especially bone metabolic diseases, including osteoporosis, hyperparathyroidism, osteomalacia, osteogenesis imperfecta, osteoarthritis, etc.", "bbox": [333, 168, 1064, 282], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "Shengguang Chen is a clinical doctor at Gongli Hospital of Shanghai Pudong New Area. He has been engaged in clinical research on endocrine and metabolic diseases. He received his Ph.D. degree in medical from Tongji University. Currently, his research interests mainly focus on the diagnosis and treatment of metabolic diseases, especially bone metabolic diseases, including osteoporosis, hyperparathyroidism, osteomalacia, osteogenesis imperfecta, osteoarthritis, etc."}, "layout_signature": {"width": 731, "width_bucket": 725, "height": 114, "left": 333, "top": 168, "right": 1064, "bottom": 282, "x_center": 698.5, "x_center_bucket": 700, "y_center": 225.0, "x_ratio": 0.5865, "y_ratio": 0.1438, "width_ratio": 0.6138, "height_ratio": 0.0728, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaSansPro-Bold", "bold": true, "italic": true, "span_count": 6}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_140", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "zone": "body_zone", "insert_score": {"score": 0.0, "decision": "body", "evidence": []}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 27, "block_id": 5, "raw_label": "image", "raw_order": null, "bbox": [120, 464, 321, 721], "text": "", "page_width": 1191, "page_height": 1565, "role": "author_bio_asset", "role_confidence": 0.85, "evidence": ["media label: image"], "seed_role": "media_asset", "seed_confidence": 0.85, "seed_evidence": ["media label: image"], "span_metadata": null, "raw_observation": {"block_id": 5, "page": 27, "raw_label": "image", "text": "", "bbox": [120, 464, 321, 721], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "empty", "raw_marker": null, "number": null, "kind": null, "normalized_text": ""}, "layout_signature": {"width": 201, "width_bucket": 200, "height": 257, "left": 120, "top": 464, "right": 321, "bottom": 721, "x_center": 220.5, "x_center_bucket": 225, "y_center": 592.5, "x_ratio": 0.1851, "y_ratio": 0.3786, "width_ratio": 0.1688, "height_ratio": 0.1642, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_139", "display_cluster_candidate_id": "disp_27_0", "layout_region": "display_zone", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"], "asset_family_hint": "figure_like", "asset_family_confidence": 0.7, "asset_family_evidence": ["raw_label:image"], "_object_owner_family": "author_bio", "_excluded_from_figure_inventory": true}
+{"paper_id": "2HEUD5P9", "page": 27, "block_id": 6, "raw_label": "text", "raw_order": 2, "bbox": [332, 460, 1062, 597], "text": "Bei Ma is a professor at Tongji Hospital affiliated to Tongji University. She obtained her Ph.D. at Second Military Medical University, China, in 2008. She did her post-doctoral work at Geoffrey Burnstock's laboratory at University College of London. She is a fellow of Chinese Association for Physiological Science and a fellow of Chinese Neuroscience Society. Currently, her research focus on the underlying physiological and pathological mechanisms of nerve damage and repair after spinal cord injury.", "page_width": 1191, "page_height": 1565, "role": "backmatter_body", "role_confidence": 0.6, "evidence": ["default body_paragraph for text label"], "seed_role": "body_paragraph", "seed_confidence": 0.6, "seed_evidence": ["default body_paragraph for text label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaSansPro-Bold", "flags": 20, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaSansPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaSansPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaSansPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaSansPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaSansPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaSansPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 6, "page": 27, "raw_label": "text", "text": "Bei Ma is a professor at Tongji Hospital affiliated to Tongji University. She obtained her Ph.D. at Second Military Medical University, China, in 2008. She did her post-doctoral work at Geoffrey Burnstock's laboratory at University College of London. She is a fellow of Chinese Association for Physiological Science and a fellow of Chinese Neuroscience Society. Currently, her research focus on the underlying physiological and pathological mechanisms of nerve damage and repair after spinal cord injury.", "bbox": [332, 460, 1062, 597], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "Bei Ma is a professor at Tongji Hospital affiliated to Tongji University. She obtained her Ph.D. at Second Military Medical University, China, in 2008. She did her post-doctoral work at Geoffrey Burnstock's laboratory at University College of London. She is a fellow of Chinese Association for Physiological Science and a fellow of Chinese Neuroscience Society. Currently, her research focus on the underlying physiological and pathological mechanisms of nerve damage and repair after spinal cord injury."}, "layout_signature": {"width": 730, "width_bucket": 725, "height": 137, "left": 332, "top": 460, "right": 1062, "bottom": 597, "x_center": 697.0, "x_center_bucket": 700, "y_center": 528.5, "x_ratio": 0.5852, "y_ratio": 0.3377, "width_ratio": 0.6129, "height_ratio": 0.0875, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaSansPro-Bold", "bold": true, "italic": true, "span_count": 7}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "", "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_140", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.0, "decision": "body", "evidence": []}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"], "_object_owner_family": "author_bio", "_excluded_from_figure_inventory": true}
+{"paper_id": "2HEUD5P9", "page": 27, "block_id": 7, "raw_label": "image", "raw_order": null, "bbox": [121, 756, 321, 1011], "text": "", "page_width": 1191, "page_height": 1565, "role": "author_bio_asset", "role_confidence": 0.85, "evidence": ["media label: image"], "seed_role": "media_asset", "seed_confidence": 0.85, "seed_evidence": ["media label: image"], "span_metadata": null, "raw_observation": {"block_id": 7, "page": 27, "raw_label": "image", "text": "", "bbox": [121, 756, 321, 1011], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "empty", "raw_marker": null, "number": null, "kind": null, "normalized_text": ""}, "layout_signature": {"width": 200, "width_bucket": 200, "height": 255, "left": 121, "top": 756, "right": 321, "bottom": 1011, "x_center": 221.0, "x_center_bucket": 225, "y_center": 883.5, "x_ratio": 0.1856, "y_ratio": 0.5645, "width_ratio": 0.1679, "height_ratio": 0.1629, "line_count": 1}, "span_signature": {"font_size": null, "font_size_median": null, "font_size_bucket": null, "font_family_norm": null, "bold": false, "italic": false, "span_count": 0}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_139", "display_cluster_candidate_id": "disp_27_0", "layout_region": "display_zone", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"], "asset_family_hint": "figure_like", "asset_family_confidence": 0.7, "asset_family_evidence": ["raw_label:image"], "_object_owner_family": "author_bio", "_excluded_from_figure_inventory": true}
+{"paper_id": "2HEUD5P9", "page": 27, "block_id": 8, "raw_label": "text", "raw_order": 3, "bbox": [332, 753, 1076, 911], "text": "Rongrong Zhu is a professor at Tongji University, affiliated Tongji hospital and Spinal Cord Injury Research Institute. She focused on the field \"Regenerative Medicine and Nanomaterials\" to regulate the microenvironment of injury site and promote the tissue regeneration through the design, optimization, synthesis of nanomaterials. She obtained her Ph.D. at Tongjii University, China, in 2007. She went on postdoctoral research at Stony Brook University in the United States in 2009. She is a member of neuroprotection group in Neuro-regeneration and Repair Committee of Chinese Research Hospitals Society, also a director of Shanghai Society for Biochemistry and Molecular Biology.", "page_width": 1191, "page_height": 1565, "role": "backmatter_body", "role_confidence": 0.6, "evidence": ["default body_paragraph for text label"], "seed_role": "body_paragraph", "seed_confidence": 0.6, "seed_evidence": ["default body_paragraph for text label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaSansPro-Bold", "flags": 20, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaSansPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaSansPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaSansPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaSansPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaSansPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaSansPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}, {"size": 8.966400146484375, "font": "ScalaSansPro-Regular", "flags": 4, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 8, "page": 27, "raw_label": "text", "text": "Rongrong Zhu is a professor at Tongji University, affiliated Tongji hospital and Spinal Cord Injury Research Institute. She focused on the field \"Regenerative Medicine and Nanomaterials\" to regulate the microenvironment of injury site and promote the tissue regeneration through the design, optimization, synthesis of nanomaterials. She obtained her Ph.D. at Tongjii University, China, in 2007. She went on postdoctoral research at Stony Brook University in the United States in 2009. She is a member of neuroprotection group in Neuro-regeneration and Repair Committee of Chinese Research Hospitals Society, also a director of Shanghai Society for Biochemistry and Molecular Biology.", "bbox": [332, 753, 1076, 911], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "Rongrong Zhu is a professor at Tongji University, affiliated Tongji hospital and Spinal Cord Injury Research Institute. She focused on the field \"Regenerative Medicine and Nanomaterials\" to regulate the microenvironment of injury site and promote the tissue regeneration through the design, optimization, synthesis of nanomaterials. She obtained her Ph.D. at Tongjii University, China, in 2007. She went on postdoctoral research at Stony Brook University in the United States in 2009. She is a member of neuroprotection group in Neuro-regeneration and Repair Committee of Chinese Research Hospitals Society, also a director of Shanghai Society for Biochemistry and Molecular Biology."}, "layout_signature": {"width": 744, "width_bucket": 750, "height": 158, "left": 332, "top": 753, "right": 1076, "bottom": 911, "x_center": 704.0, "x_center_bucket": 700, "y_center": 832.0, "x_ratio": 0.5911, "y_ratio": 0.5316, "width_ratio": 0.6247, "height_ratio": 0.101, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaSansPro-Bold", "bold": true, "italic": true, "span_count": 8}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "", "style_family": "unknown_like", "style_family_authority": "fallback", "reading_band_id": "band_140", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.0, "decision": "body", "evidence": []}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"], "_object_owner_family": "author_bio", "_excluded_from_figure_inventory": true}
+{"paper_id": "2HEUD5P9", "page": 27, "block_id": 9, "raw_label": "footer", "raw_order": null, "bbox": [99, 1487, 289, 1505], "text": "Small Methods 2024, 8, 2301283", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["footer label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["footer label"], "span_metadata": [{"size": 6.973800182342529, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Bold", "flags": 20, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Italic", "flags": 6, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}, {"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 9, "page": 27, "raw_label": "footer", "text": "Small Methods 2024, 8, 2301283", "bbox": [99, 1487, 289, 1505], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "Small Methods 2024, 8, 2301283"}, "layout_signature": {"width": 190, "width_bucket": 200, "height": 18, "left": 99, "top": 1487, "right": 289, "bottom": 1505, "x_center": 194.0, "x_center_bucket": 200, "y_center": 1496.0, "x_ratio": 0.1629, "y_ratio": 0.9559, "width_ratio": 0.1595, "height_ratio": 0.0115, "line_count": 1}, "span_signature": {"font_size": 6.97, "font_size_median": 6.97, "font_size_bucket": 7.0, "font_family_norm": "ScalaSansPro-Italic", "bold": true, "italic": true, "span_count": 5}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_138", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 27, "block_id": 10, "raw_label": "number", "raw_order": null, "bbox": [527, 1484, 668, 1508], "text": "2301283 (27 of 27)", "page_width": 1191, "page_height": 1565, "role": "reference_item", "role_confidence": 0.9, "evidence": ["page number label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["page number label"], "span_metadata": [{"size": 8.966400146484375, "font": "ScalaSansPro-Bold", "flags": 20, "color": 0, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 10, "page": 27, "raw_label": "number", "text": "2301283 (27 of 27)", "bbox": [527, 1484, 668, 1508], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "reference_numeric_dot", "raw_marker": "2301283", "number": 2301283, "kind": "reference", "normalized_text": "2301283 (27 of 27)"}, "layout_signature": {"width": 141, "width_bucket": 150, "height": 24, "left": 527, "top": 1484, "right": 668, "bottom": 1508, "x_center": 597.5, "x_center_bucket": 600, "y_center": 1496.0, "x_ratio": 0.5017, "y_ratio": 0.9559, "width_ratio": 0.1184, "height_ratio": 0.0153, "line_count": 1}, "span_signature": {"font_size": 8.97, "font_size_median": 8.97, "font_size_bucket": 9.0, "font_family_norm": "ScalaSansPro-Bold", "bold": true, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": true, "index_default": true, "zone": "reference_zone", "style_family": "reference_like", "style_family_authority": "reference_family_anchor", "reading_band_id": "band_141", "display_cluster_candidate_id": "", "layout_region": "reference_candidate", "boundary_before": "hard", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "reference_zone_fallback", "role_evidence": ["reference item accepted (pre-gate resolution, empty zone)"]}
+{"paper_id": "2HEUD5P9", "page": 27, "block_id": 11, "raw_label": "footer", "raw_order": null, "bbox": [938, 1487, 1095, 1506], "text": "© 2024 Wiley-VCH GmbH", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.9, "evidence": ["footer label"], "seed_role": "noise", "seed_confidence": 0.9, "seed_evidence": ["footer label"], "span_metadata": [{"size": 6.973800182342529, "font": "ScalaSansPro-Regular", "flags": 4, "color": 2301728, "dir": [1.0, 0.0], "wmode": 0}], "raw_observation": {"block_id": 11, "page": 27, "raw_label": "footer", "text": "© 2024 Wiley-VCH GmbH", "bbox": [938, 1487, 1095, 1506], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "© 2024 Wiley-VCH GmbH"}, "layout_signature": {"width": 157, "width_bucket": 150, "height": 19, "left": 938, "top": 1487, "right": 1095, "bottom": 1506, "x_center": 1016.5, "x_center_bucket": 1025, "y_center": 1496.5, "x_ratio": 0.8535, "y_ratio": 0.9562, "width_ratio": 0.1318, "height_ratio": 0.0121, "line_count": 1}, "span_signature": {"font_size": 6.97, "font_size_median": 6.97, "font_size_bucket": 7.0, "font_family_norm": "ScalaSansPro-Regular", "bold": false, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_142", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
+{"paper_id": "2HEUD5P9", "page": 27, "block_id": 12, "raw_label": "aside_text", "raw_order": null, "bbox": [1155, 31, 1171, 1536], "text": "2369606, 2024, 8, Downloaded from https://onlinelibrary.wiley.com/doi/10.1002/smld.202301283 by Shandong University Library, Wiley Online Library on [18/02/2026]. See the Terms and Conditions (https://onlinelibrary.wiley.com/terms-and-conditions) on Wiley Online Library for rules of use; OA articles are governed by the applicable Creative Commons License.", "page_width": 1191, "page_height": 1565, "role": "noise", "role_confidence": 0.95, "evidence": ["margin-band narrow/tall geometry; treated as noise"], "seed_role": "noise", "seed_confidence": 0.95, "seed_evidence": ["margin-band narrow/tall geometry; treated as noise"], "span_metadata": [{"size": 5.03000020980835, "font": "Times-Roman", "flags": 4, "color": 0, "dir": [0.0, 1.0], "wmode": 0}], "raw_observation": {"block_id": 12, "page": 27, "raw_label": "aside_text", "text": "2369606, 2024, 8, Downloaded from https://onlinelibrary.wiley.com/doi/10.1002/smld.202301283 by Shandong University Library, Wiley Online Library on [18/02/2026]. See the Terms and Conditions (https://onlinelibrary.wiley.com/terms-and-conditions) on Wiley Online Library for rules of use; OA articles are governed by the applicable Creative Commons License.", "bbox": [1155, 31, 1171, 1536], "page_width": 1191, "page_height": 1565}, "marker_signature": {"type": "none", "raw_marker": null, "number": null, "kind": "generic_text", "normalized_text": "2369606, 2024, 8, Downloaded from https://onlinelibrary.wiley.com/doi/10.1002/smld.202301283 by Shandong University Library, Wiley Online Library on [18/02/2026]. See the Terms and Conditions (https://onlinelibrary.wiley.com/terms-and-conditions) on Wiley Online Library for rules of use; OA articles are governed by the applicable Creative Commons License."}, "layout_signature": {"width": 16, "width_bucket": 25, "height": 1505, "left": 1155, "top": 31, "right": 1171, "bottom": 1536, "x_center": 1163.0, "x_center_bucket": 1175, "y_center": 783.5, "x_ratio": 0.9765, "y_ratio": 0.5006, "width_ratio": 0.0134, "height_ratio": 0.9617, "line_count": 1}, "span_signature": {"font_size": 5.03, "font_size_median": 5.03, "font_size_bucket": 5.0, "font_family_norm": "Times-Roman", "bold": false, "italic": true, "span_count": 1}, "_in_visual_container": null, "_container_bbox": null, "_container_text": null, "_text_source": null, "_ocr_raw_status": null, "_ocr_raw_error_type": null, "render_default": false, "index_default": false, "zone": "", "style_family": "body_like", "style_family_authority": "body_zone_with_anchor", "reading_band_id": "band_142", "display_cluster_candidate_id": "", "layout_region": "body_flow", "boundary_before": "none", "boundary_after": "none", "bridge_eligible": false, "insert_score": {"score": 0.15, "decision": "body", "evidence": ["narrow_width"]}, "role_verification_status": "ACCEPT", "role_source": "non_structural_normalized_role", "role_evidence": ["pre-gate normalized non-structural role preserved"]}
diff --git a/tests/test_ocr_figure_vnext_real_papers.py b/tests/test_ocr_figure_vnext_real_papers.py
new file mode 100644
index 00000000..c90af066
--- /dev/null
+++ b/tests/test_ocr_figure_vnext_real_papers.py
@@ -0,0 +1,14 @@
+from pathlib import Path
+
+from scripts.dev.compare_figure_inventory_legacy_vs_vnext import compare_blocks_file
+
+
+def test_real_paper_same_page_milestone_reports_diff_shape():
+ blocks_path = Path("tests/fixtures/ocr_vnext_real_papers/2HEUD5P9/blocks.structured.jsonl")
+ diff = compare_blocks_file(blocks_path)
+
+ assert diff["paper"] == "2HEUD5P9"
+ assert "legacy_matched_count" in diff
+ assert "vnext_matched_count" in diff
+ assert "legacy_consumed_block_ids" in diff
+ assert "vnext_consumed_block_ids" in diff